MCID: DDN006
MIFTS: 42

Duodenitis malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Duodenitis

Aliases & Descriptions for Duodenitis:

Name: Duodenitis 12 52 42 14 69
Hemorrhagic Duodenitis 12 69
Acute Enteritis of the Mouse Intestinal Tract 69

Classifications:



External Ids:

Disease Ontology 12 DOID:8643
ICD10 33 K29.8
ICD9CM 35 535.6
MeSH 42 D004382
NCIt 47 C94409
SNOMED-CT 64 155715004 72007001
UMLS 69 C0013298

Summaries for Duodenitis

MalaCards based summary : Duodenitis, also known as hemorrhagic duodenitis, is related to duodenal atresia and duodenal ulcer. An important gene associated with Duodenitis is GAST (Gastrin), and among its related pathways/superpathways are Downstream signaling events of B Cell Receptor (BCR) and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Ranitidine and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, colon and testes.

Wikipedia : 71 Duodenitis is inflammation of the duodenum. It may persist acutely or... more...

Related Diseases for Duodenitis

Diseases related to Duodenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 484)
id Related Disease Score Top Affiliating Genes
1 duodenal atresia 12.2
2 duodenal ulcer 12.2
3 duodenal obstruction 12.0
4 duodenal gastrinoma 12.0
5 duodenal disease 12.0
6 duodenal somatostatinoma 11.9
7 chronic duodenal ileus 11.9
8 feingold syndrome 11.9
9 tremor, nystagmus, and duodenal ulcer 11.8
10 duodenal carcinoid syndrome 11.8
11 pancreatic lipomatosis duodenal stenosis 11.8
12 duodenal ulcer due to antral g-cell hyperfunction 11.7
13 duodenal atresia tetralogy of fallot 11.7
14 duodenum cancer 11.6
15 peptic ulcer disease 11.2
16 superior mesenteric artery syndrome 11.1
17 adenomatous polyposis coli 11.0
18 chronic erosive gastritis 10.9
19 ciliary dyskinesia, primary, 31 10.8
20 mitchell-riley syndrome 10.7
21 pancreatic lipase deficiency 10.7
22 multiple endocrine neoplasia 1 10.7
23 feingold syndrome 2 10.7
24 immunodeficiency 12 10.7
25 pancreas, annular 10.7
26 duodenum adenoma 10.7
27 ladd syndrome 10.7
28 neuhauser daly magnelli syndrome 10.7
29 gastritis 10.7
30 pancreatitis 10.4
31 gastroduodenitis 10.4
32 atrophic gastritis 10.3
33 paranasal sinus cancer, adult 10.2 GAST INS
34 esophagitis 10.2
35 schneiderian carcinoma 10.1 CD79A GAST
36 familial adenomatous polyposis 10.1
37 acute pyelonephritis 10.1 GAST INS
38 acute eustachian salpingitis 10.1 GAST S100A8
39 acute kidney tubular necrosis 10.1 CD79A GAST
40 hyperlipoproteinemia type iii 10.1 CD79A INS
41 maturity-onset diabetes of the young, type 13 10.1 GAST INS
42 keloids 10.1 GAST INS
43 secondary syphilis 10.1 ATP4A GAST
44 mucositis 10.1
45 dyspepsia 10.1
46 brain edema 10.1 ATP4A GAST
47 gastrinoma 10.1
48 somatostatinoma 10.1
49 adenoma 10.1
50 liver rhabdomyosarcoma 10.1 ATP4A GAST

Comorbidity relations with Duodenitis via Phenotypic Disease Network (PDN): (show all 16)


Active Peptic Ulcer Disease Acute Cystitis
Acute Pancreatitis Atrophic Gastritis
Bronchitis Chronic Kidney Failure
Chronic Myocardial Ischemia Deficiency Anemia
Esophageal Disease Esophagitis
Heart Disease Hypertension, Essential
Intermediate Coronary Syndrome Iron Deficiency Anemia
Ischemic Heart Disease Paralytic Ileus

Graphical network of the top 20 diseases related to Duodenitis:



Diseases related to Duodenitis

Symptoms & Phenotypes for Duodenitis

Drugs & Therapeutics for Duodenitis

Drugs for Duodenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ranitidine Approved Phase 4 66357-59-3, 66357-35-5 3001055
2
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
3
Proton pump inhibitors Phase 4,Phase 3
4 Gastrointestinal Agents Phase 4,Phase 3
5 Antacids Phase 4,Phase 3
6 Anti-Ulcer Agents Phase 4,Phase 3
7 Ranitidine bismuth citrate Phase 4
8
Dexlansoprazole Phase 4 138530-94-6, 103577-45-3 9578005
9
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
10
Ofloxacin Approved Phase 3 82419-36-1 4583
11
Doxycycline Approved, Investigational, Vet_approved Phase 3 564-25-0 54671203
12
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
13
Nitazoxanide Approved, Investigational, Vet_approved Phase 3 55981-09-4 41684
14 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
15 Cytochrome P-450 Enzyme Inhibitors Phase 3
16 Topoisomerase Inhibitors Phase 3
17 Anti-Bacterial Agents Phase 3
18 Anti-Infective Agents Phase 3
19 Antimalarials Phase 3
20 Renal Agents Phase 3
21 Antiparasitic Agents Phase 3
22 Antiprotozoal Agents Phase 3

Interventional clinical trials:


id Name Status NCT ID Phase
1 Is a Reporting System for Gastritis or Duodenitis (Modified Lanza Scale) Reproducible? Completed NCT00852150 Phase 4
2 Lansoprazole Preventing Gastroduodenal Stress Ulcerations Terminated NCT00220909 Phase 4
3 A Two Week Nitazoxanidebased Quadruple Regimen Recruiting NCT02621359 Phase 3
4 Effectiveness of Biofeedback-Assisted Relaxation Training in Children With Eosinophilic Duodenitis Completed NCT00124501

Search NIH Clinical Center for Duodenitis

Cochrane evidence based reviews: duodenitis

Genetic Tests for Duodenitis

Anatomical Context for Duodenitis

MalaCards organs/tissues related to Duodenitis:

39
Pancreas, Colon, Testes, Liver, T Cells, Kidney, Small Intestine

Publications for Duodenitis

Articles related to Duodenitis:

(show top 50) (show all 2915)
id Title Authors Year
1
Duodenal gastrointestinal stromal tumor presenting as pancreatic head mass - a case report. ( 28523328 )
2017
2
The Role of Duodenal Inflammation in Functional Dyspepsia. ( 27811629 )
2017
3
Acute kidney injury following vomiting and diarrhea after endoscopy in a duodenal gastrinoma patient. ( 28070096 )
2017
4
Detection of an Infant's Duodenal Atresia by Milk Scan. ( 28060781 )
2017
5
Allelic frequencies of the hs1.2 enhancer within the immunoglobulin heavy chain region in Dayton, Ohio patients screened for celiac disease with duodenal biopsy. ( 28473300 )
2017
6
Duodenitis-Proximal Jejunitis in Horses After Experimental Administration of Clostridium difficile Toxins. ( 27906466 )
2017
7
Dosimetric parameters correlate with duodenal histopathologic damage after stereotactic body radiotherapy for pancreatic cancer: Secondary analysis of a prospective clinical trial. ( 28089484 )
2017
8
BRUNNER GLAND ADENOMA MASQUERADING AS DUODENAL GASTROINTESTINAL STROMAL TUMOR WITH INTUSSUSCEPTION: CASE REPORT. ( 28489176 )
2017
9
Closure of duodenal ulcer perforation using a novel endoloop device with a single-channel gastroscope after failed laparoscopic repair. ( 28068696 )
2017
10
Spontaneous Intramural Duodenal Hematoma: Pancreatitis, Obstructive Jaundice, and Upper Intestinal Obstruction. ( 27891286 )
2016
11
Ultrasound follow-up in a patient with intestinal obstruction due to post-traumatic intramural duodenal hematoma. ( 27194436 )
2016
12
Duodenal Recurrence of Fibrolamellar Carcinoma 12 Years After Partial Hepatectomy and Adjuvant Chemotherapy. ( 27921059 )
2016
13
Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa. ( 27830096 )
2016
14
'Rare' manifestation of 'rare' disease: sarcoidosis presenting as pancreatitis, duodenal ulcer and severe acute kidney injury. ( 27506671 )
2016
15
Hypergastrinemia and a duodenal ulcer caused by gastric duplication. ( 27464496 )
2016
16
Temporary placement of a covered duodenal stent can avoid riskier anterograde biliary drainage when ERCP for obstructive jaundice fails due to duodenal invasion. ( 27324333 )
2016
17
Peritonitis Following Duodenal Ulcer Perforation in a Newborn: A Case Report. ( 28050434 )
2016
18
A life-threatening duodenal ulcer hemorrhage due to previously unknown primary hyperparathyroidism. ( 27616071 )
2016
19
Serendipity in Refractory Celiac Disease: Full Recovery of Duodenal Villi and Clinical Symptoms after Fecal Microbiota Transfer. ( 27689204 )
2016
20
A Case of Lung Squamous Cell Carcinoma With Duodenal Metastasis on FDG PET/CT. ( 27055139 )
2016
21
PERFORATED DUODENAL ULCER ASSOCIATED WITH SITUS INVERSUS AND DEXTROCARDIA. ( 27323596 )
2016
22
Duodenal siderosis: a rare clinical finding in a patient with duodenal inflammation. ( 27366043 )
2016
23
Temporary duodenal stenting as a bridge to ERCP for inaccessible papilla due to duodenal obstruction: a retrospective study. ( 27652301 )
2016
24
Duodenal Ulcer Induced by Hem-o-Lok clip after Reduced Port Laparoscopic Cholecystectomy. ( 27014759 )
2016
25
Genome Sequence of Kocuria palustris Strain CD07_3 Isolated from the Duodenal Mucosa of a Celiac Disease Patient. ( 27125478 )
2016
26
Preduodenal Portal Vein Associated with Duodenal Obstruction of other Etiology: A Case Series. ( 27896162 )
2016
27
Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease. ( 26153762 )
2016
28
Duodeno-duodenostomy or duodeno-jejunostomy for duodenal atresia: is one repair better than the other? ( 27858187 )
2016
29
Feasibility of Cold Snare Polypectomy for Multiple Duodenal Adenomas in Patients with Familial Adenomatous Polyposis: A Pilot Study. ( 27126203 )
2016
30
Maturity onset diabetes of the young 5 accompanied by duodenal cysts. ( 26676964 )
2016
31
Successful Conservative Treatment of a Cholecystoduodenal Fistula Caused by a Cytomegalovirus-associated Duodenal Ulcer. ( 27629956 )
2016
32
Frequency and Features of Duodenal Adenomas in Patients WithA MUTYH-Associated Polyposis. ( 26905905 )
2016
33
Congenital Duodenal Obstruction in Neonates: Over 13 Years' Experience from a Single Centre. ( 27896158 )
2016
34
Helicobacter pylori Strains from Duodenal Ulcer Patients Exhibit Mixed babA/B Genotypes with Low Levels of BabA Adhesin and Lewis b Binding. ( 27318698 )
2016
35
Modeling the cost-effectiveness of ilaprazole versus omeprazole for the treatment of newly diagnosed duodenal ulcer patients in China. ( 27223846 )
2016
36
Long QT Syndrome and Duodenal Ampullary Adenoma: A New Association. ( 27921062 )
2016
37
Coexisting urogenital anomaly and duodenal atresia in two atypical Holt-Oram syndrome. ( 27695215 )
2016
38
Can supplementation of phytoestrogens/insoluble fibers help the management of duodenal polyps in familial adenomatous polyposis? ( 27207660 )
2016
39
Detection of Minute Duodenal Follicular Lymphoma Lesions Using Magnifying Endoscopy. ( 27094839 )
2016
40
Discordant lymphoma of duodenal EBV-positive peripheral T-cell lymphoma not otherwise specified and ileal diffuse large B-cell lymphoma. ( 27169448 )
2016
41
Total duodenal necrosis with retroperitoneal perforation in an adolescent with jejunal intussusception. ( 27206647 )
2016
42
Pancreas-sparing total duodenectomy for Spigelman stage IV duodenal polyposis associated with familial adenomatous polyposis: experience of 10 cases at a single institution. ( 27655252 )
2016
43
Celiac disease: is it really possible to overcome duodenal biopsy? ( 27163902 )
2016
44
How to treat a neonate with duodenal atresia and intrapancreatic choledochocele causing persistent hyperbilirubinemia: A case report. ( 26701845 )
2016
45
Simultaneous occurrence of intussusception and duodenal haematoma in a patient with Glanzmann's thrombasthenia. ( 28051053 )
2016
46
Duodenal atresia with apple-peel configuration of the ileum and absent superior mesenteric artery. ( 27596226 )
2016
47
Ethnic Variations in Duodenal Villous Atrophy Consistent with Celiac Disease in the United States. ( 27155557 )
2016
48
Association of Duodenal Atresia, Malrotation, and Atrial Septal Defect in a Down-Syndrome Patient. ( 27170921 )
2016
49
The Selective Arterial Calcium Injection Test is a Valid Diagnostic Method for Invisible Gastrinoma with Duodenal Ulcer Stenosis: A Case Report. ( 27348901 )
2016
50
Pyopneumothorax and peritonitis due to perforated duodenal ulcer and associated pleuroperitoneal communication. ( 27372035 )
2016

Variations for Duodenitis

Expression for Duodenitis

Search GEO for disease gene expression data for Duodenitis.

Pathways for Duodenitis

Pathways related to Duodenitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.77 CD79A INS MALT1
2 11.14 CD79A INS
3 9.32 ATP4A GAST

GO Terms for Duodenitis

Cellular components related to Duodenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 secretory granule lumen GO:0034774 8.96 INS S100A8
2 extracellular space GO:0005615 8.92 ATP4A GAST INS S100A8

Biological processes related to Duodenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 wound healing GO:0042060 9.26 INS S100A8
2 positive regulation of cell growth GO:0030307 9.16 INS S100A8
3 B cell activation GO:0042113 8.96 CD79A MALT1
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 8.8 INS MALT1 S100A8

Molecular functions related to Duodenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.96 GAST INS
2 protease binding GO:0002020 8.62 INS MALT1

Sources for Duodenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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