MCID: DDN006
MIFTS: 48

Duodenitis malady

Gastrointestinal diseases category

Aliases & Classifications for Duodenitis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 27ICD9CM, 33MeSH, 25ICD10
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Duodenitis, Aliases & Descriptions:

Name: Duodenitis 9 11 43 60
Hemorrhagic Duodenitis 9 60
 
Acute Enteritis of the Mouse Intestinal Tract 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology9 DOID:8643
ICD9CM27 535.6
SNOMED-CT55 72007001, 155715004
MeSH33 D004382
ICD1025 K29.8

Summaries for Duodenitis

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Wikipedia:63 Duodenitis is inflammation of the duodenum. It may persist acutely or chronically. more...

MalaCards based summary: Duodenitis, also known as hemorrhagic duodenitis, is related to duodenal ulcer and gastritis. An important gene associated with Duodenitis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are Selected targets of GCR alpha and Insulin receptor recycling. The compounds calcium gluconate and i-app have been mentioned in the context of this disorder. Affiliated tissues include pancreas, colon and testes, and related mouse phenotypes are immune system and digestive/alimentary.

Related Diseases for Duodenitis

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Diseases related to Duodenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 497)
idRelated DiseaseScoreTop Affiliating Genes
1duodenal ulcer32.2S100A8, GAST
2gastritis31.4GAST, S100A8
3gastric ulcer31.0GAST, S100A8
4gastric outlet obstruction30.9ATP4A, GAST, ATP12A
5dyspepsia30.8GAST, ATP4A, ATP12A
6gastrinoma30.8ATP4A, GAST, ATP12A
7adenoma30.6S100A8, GAST, INS
8atrophic gastritis30.6S100A8, GAST
9hiatus hernia30.5ATP4A, ATP12A
10insulinoma30.4INS, GAST
11bile reflux30.2ATP4A, ATP12A
12irritable bowel syndrome30.1ATP12A, ATP4A
13hypoglycemia30.1INS, GAST
14esophagitis30.1GAST, ATP4A, S100A8, ATP12A, IL5
15peptic ulcer disease30.0S100A8, GAST, ATP4A, ATP12A
16gastric adenocarcinoma30.0S100A8, GAST
17hyperinsulinemic hypoglycemia30.0GAST, INS
18diarrhea29.9ATP12A, GAST, INS, ATP4A
19gastroesophageal reflux29.8GAST, ATP12A, ATP4A, S100A8
20laryngitis29.8ATP12A, ATP4A
21stomach cancer29.8GAST, ATP4A, ATP12A
22esophageal cancer29.7ATP12A, ATP4A
23achalasia29.6ATP4A, GAST, ATP12A
24asthma29.0S100A8, IL5, ATP12A, ATP4A
25duodenal obstruction11.1
26duodenal atresia10.9
27pancreatitis10.9
28annular pancreas10.6
29somatostatinoma10.6
30duodenal somatostatinoma10.6
31aneurysm10.5
32duodenal gastrinoma10.5
33acute pancreatitis10.5
34adenocarcinoma10.5
35aortic aneurysm10.5
36ileus10.5
37gastrointestinal stromal tumor10.4
38celiac disease10.4
39pancreatic cancer10.4
40abdominal aortic aneurysm10.4
41zollinger-ellison syndrome10.4
42situs inversus10.4
43gastroduodenitis10.4
44duodenal disease10.4
45blindness10.4
46chronic duodenal ileus10.4
47superior mesenteric artery syndrome10.4
48feingold syndrome10.3
49hepatitis10.3
50giardiasis10.3

Graphical network of the top 20 diseases related to Duodenitis:



Diseases related to duodenitis

Symptoms for Duodenitis

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Drugs & Therapeutics for Duodenitis

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Drug clinical trials:

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Search NIH Clinical Center for Duodenitis

Genetic Tests for Duodenitis

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Anatomical Context for Duodenitis

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MalaCards organs/tissues related to Duodenitis:

31
Pancreas, Colon, Testes, Liver, Small intestine, T cells, Kidney, Lung, Lymph node, Thyroid, Breast, Heart, Bone, Myeloid, B cells, Endothelial, Pancreatic islet, Neutrophil, Bone marrow, Skin, Ovary, Spleen, Smooth muscle, Monocytes, Pituitary

Animal Models for Duodenitis or affiliated genes

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MGI Mouse Phenotypes related to Duodenitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.3GAST, IL5, INS, ATP4A
2MP:00053817.6GAST, IL5, INS, ATP12A, ATP4A
3MP:00053767.4ATP4A, ATP12A, INS, IL5, GAST

Publications for Duodenitis

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Articles related to Duodenitis:

(show top 50)    (show all 2681)
idTitleAuthorsYear
1
Thyroid storm precipitated by duodenal ulcer perforation. (25838951)
2015
2
Closure of a perforated duodenal ulcer by over-the-scope clip. (25028271)
2014
3
Acute segmentary ulcerative duodenitis induced by Streptococcus pyogenes mimicking inflammatory bowel disease. (23994254)
2013
4
Proximal duodenal obstruction--Bouveret's syndrome revisited. (23945924)
2013
5
Endoscopic submucosal dissection of a duodenal neuroendocrine tumor. (24368076)
2013
6
Acute mesenteric ischemia and duodenal ulcer perforation: a unique double pathology. (23110681)
2012
7
Association of genetic polymorphisms in IL17A and IL17F with gastro-duodenal diseases. (23012664)
2012
8
Duodenal gastrinoma with multiple gastric neuroendocrine tumors secondary to chronic Helicobacter pylori gastritis. (22588069)
2012
9
Isolated Russell body duodenitis. (21234686)
2011
10
Superior mesenteric artery syndrome: risk factor for duodenal involvement in Henoch-SchAPnlein purpura. (21129122)
2011
11
Atherosclerosis and acetylsalicylic acid are independent risk factors for hemorrhage in patients with gastric or duodenal ulcer. (21220246)
2011
12
An unusual case of ulcerative duodenitis. (21722640)
2011
13
Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch. (20492663)
2010
14
Hemorrhagic gastritis and duodenitis following celiac plexus neurolysis. (19935986)
2009
15
Bleeding duodenal ulcer with a right upper quadrant mass. (18268056)
2008
16
Interleukin-1beta gene polymorphism as a predictor of eradication treatment efficacy in gastric and duodenal ulcer associated with Helicobacter pylori]. (19145908)
2008
17
Toll-like receptor (TLR2, TLR4 and TLR5) gene polymorphisms and Helicobacter pylori infection in children with and without duodenal ulcer. (18809506)
2008
18
High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model. (17868414)
2007
19
Unexpected superimposition of nutcracker effect in various conditions: is it an unrecognized confounding factor? Comment on: Henoch-Schonlein purpura presenting duodenal involvement similar to superior mesenteric artery syndrome in a girl. (Eur J Pediatr. 2006 Sep 29; [Epub ahead of print]). (17180389)
2007
20
Duodenal switch operation for pathologic transpyloric duodenogastric reflux. (17245178)
2007
21
Pyloric obstruction, duodenal dilatation, and extrahepatic cholestasis: a neonatal triad suggesting multiple intestinal atresias. (17011287)
2006
22
Duodenal and gastric Dieulafoy's lesions in a patient with type 2A von Willebrand's disease. (15729257)
2005
23
A long-term survival case with multiple liver metastases from duodenal gastrointestinal stromal tumor that was drastically reduced by the treatment with imatinib]. (16315926)
2005
24
Duodeno-jejunal anastomosis with trans anastomotic nasojejunal tube for congenital duodenal obstruction. (15951892)
2005
25
Decreased epithelial cytokine responses in the duodenal mucosa of Helicobacter pylori-infected duodenal ulcer patients. (12522049)
2003
26
Embolization of a duodenal arteriovenous malformation in hereditary hemorrhagic telangiectasia: case report and review of the literature. (14631462)
2003
27
Different effect of antiulcer agents on rat cysteamine-induced duodenal ulcer after sialoadenectomy, but not gastrectomy. (14512101)
2003
28
Jejunoileal bypass changes the duodenal cholecystokinin and somatostatin cell density. (12935359)
2003
29
The sixth decision regarding perforated duodenal ulcer. (12500837)
2002
30
Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas. (11744604)
2002
31
14C urea breath test does not predict density of Helicobacter pylori in duodenal ulcer disease. (11558321)
2001
32
Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humans. (10764704)
2000
33
Intraductal secretin test is as useful as duodenal secretin test in assessing exocrine pancreatic function. (9073129)
1997
34
Presence of the cagA gene in the majority of Helicobacter pylori strains is independent of whether the individual has duodenal ulcer or asymptomatic gastritis. (9398887)
1996
35
Helicobacter pylori and duodenal ulcer: evidence for a histamine pathways-involving link. (8931414)
1996
36
Human giardiasis. A morphometric study of duodenal biopsy specimens in relation to the trophozoite count in the duodenal aspirate. (8080358)
1994
37
Paroxysmal nocturnal hemoglobinuria associated with venous thrombosis and papillary endothelial hyperplasia presenting as ulcerated duodenal mass. (8060237)
1994
38
Effect of duodenal switch procedure on gastric acid production, intragastric pH, gastric emptying, and gastrointestinal hormones. (1733373)
1992
39
Patients with duodenitis have gastric secretory and motor functions like those of duodenal ulcer patients: results of a short-term treatment with ranitidine. (2066545)
1991
40
Ceruloplasmin activity in blood serum in stomach and duodenal ulcers]. (1966196)
1990
41
Outcome of ulcer-associated duodenitis after short-term medical treatment. (4006645)
1985
42
Morphological aspects of duodenitis. (6962534)
1982
43
Value of serial sonography in the in utero detection of duodenal atresia. (7070738)
1982
44
Duodenal diaphragm associated with superior mesenteric artery syndrome. (7457748)
1981
45
Duodenal obstruction in the newborn. (5980964)
1966
46
A five-to ten-year follow-up study of the Billroth I and Billroth II (polya) operations for duodenal, gastric and gastrojejunal ulcer and gastroenterostomy with vagotomy in the treatment of duodenal ulcer. (13480410)
1957
47
Chronic duodenal ileus. (13185184)
1954
48
Duodenal obstruction in infants and children. (13079414)
1953
49
Complete duodenal obstruction in the newborn. (21020171)
1946
50
THE PRE- AND POSTOPERATIVE EMPLOYMENT OF A BRASSTIPPED GASTRODUODENAL TUBE AS AN AID IN THE SURGICAL TREATMENT OF DUODENAL OBSTRUCTION IN THE NEWBORN. (17858187)
1943

Variations for Duodenitis

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Expression for genes affiliated with Duodenitis

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Search GEO for disease gene expression data for Duodenitis.

Pathways for genes affiliated with Duodenitis

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Compounds for genes affiliated with Duodenitis

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Compounds related to Duodenitis according to GeneCards Suite gene sharing:

(show all 34)
idCompoundScoreTop Affiliating Genes
1calcium gluconate439.9INS, GAST
2i-app439.9GAST, INS
3methacholine43 49 1211.8IL5, GAST
44-ipp599.8IL5, S100A8
5git 27599.8IL5, S100A8
6starch439.8GAST, INS
7nicotinamide43 1210.8GAST, INS
8pirfenidone43 5910.8S100A8, IL5
9erythromycin43 2 49 1212.8GAST, IL5
10as 10143 5910.8S100A8, IL5
11octreotide43 59 28 1212.7INS, GAST
12amoxicillin43 49 1211.7S100A8, GAST
13c-peptide439.7GAST, INS
14metronidazole43 1210.7GAST, S100A8
15allergens439.6S100A8, IL5
16isoproterenol43 1210.5GAST, IL5
17esomeprazole43 49 1211.5ATP4A, GAST
18rabeprazole43 49 24 1212.5GAST, ATP4A
19hydrocortisone43 2 59 1212.5GAST, IL5, INS
20thyroxine43 2410.5GAST, IL5, INS
21lansoprazole43 49 24 1212.5ATP4A, GAST
22thalidomide43 49 59 1212.3S100A8, IL5
23tetracycline43 1210.3GAST, S100A8
24clarithromycin43 1210.3IL5, S100A8, GAST
25histamine43 28 2411.2IL5, S100A8, GAST
26testosterone43 59 24 1212.2INS, IL5, GAST
27creatinine439.1GAST, S100A8, INS
28pantoprazole43 49 24 1212.0GAST, ATP12A, ATP4A
29omeprazole43 49 28 24 1212.9GAST, S100A8, ATP4A
30dexamethasone43 49 28 1211.8INS, IL5, S100A8, GAST
31glutamate438.8INS, IL5, S100A8, GAST
32serine438.7INS, IL5, S100A8, GAST
33tyrosine438.6INS, IL5, S100A8, GAST
34alanine438.6INS, S100A8, GAST

GO Terms for genes affiliated with Duodenitis

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Cellular components related to Duodenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.5GAST, S100A8, IL5, INS
2extracellular spaceGO:00056157.9S100A8, IL5, INS, ATP4A

Biological processes related to Duodenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1wound healingGO:00420609.4S100A8, INS
2positive regulation of NF-kappaB transcription factor activityGO:00510929.4S100A8, INS
3positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.3IL5, INS
4positive regulation of cell growthGO:00303079.3INS, S100A8
5ATP biosynthetic processGO:00067549.2ATP12A, ATP4A

Molecular functions related to Duodenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.5GAST, INS
2hydrogen:potassium-exchanging ATPase activityGO:00089008.8ATP12A, ATP4A

Products for genes affiliated with Duodenitis

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Sources for Duodenitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet