MCID: DDN006
MIFTS: 56

Duodenitis malady

Gastrointestinal diseases category
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Summaries for Duodenitis

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Wikipedia:65 Duodenitis is inflammation of the duodenum. It may persist acutely or chronically. more...

MalaCards based summary: Duodenitis, also known as hemorrhagic duodenitis, is related to duodenal ulcer and gastritis. An important gene associated with Duodenitis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are Selected targets of GCR alpha and Insulin receptor recycling. The compounds calcium gluconate and i-app have been mentioned in the context of this disorder. Affiliated tissues include pancreas, colon and testes, and related mouse phenotypes are immune system and digestive/alimentary.

Aliases & Classifications for Duodenitis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 34MeSH, 27ICD9CM, 57SNOMED-CT, 25ICD10
See all sources

Duodenitis, Aliases & Descriptions:

Name: Duodenitis 8 10 44
Hemorrhagic Duodenitis 8 62
 
Acute Enteritis of the Mouse Intestinal Tract 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology8 DOID:8643
MeSH34 D004382
SNOMED-CT57 72007001, 155715004
ICD9CM27 535.6
ICD1025 K29.8

Related Diseases for Duodenitis

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Diseases related to Duodenitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 500)
idRelated DiseaseScoreTop Affiliating Genes
1duodenal ulcer32.2S100A8, GAST
2gastritis31.4GAST, S100A8
3gastric ulcer31.0GAST, S100A8
4gastric outlet obstruction30.9ATP4A, GAST, ATP12A
5dyspepsia30.8GAST, ATP4A, ATP12A
6gastrinoma30.8ATP4A, GAST, ATP12A
7adenoma30.6S100A8, GAST, INS
8atrophic gastritis30.6S100A8, GAST
9hiatus hernia30.5ATP4A, ATP12A
10insulinoma30.4INS, GAST
11bile reflux30.2ATP4A, ATP12A
12barrett's esophagus30.2S100A8, GAST
13esophagitis30.1GAST, ATP4A, S100A8, ATP12A, IL5
14hypoglycemia30.0INS, GAST
15irritable bowel syndrome30.0ATP12A, ATP4A
16peptic ulcer disease30.0S100A8, GAST, ATP4A, ATP12A
17hyperinsulinemic hypoglycemia30.0GAST, INS
18diarrhea29.9ATP12A, GAST, INS, ATP4A
19laryngitis29.8ATP12A, ATP4A
20stomach cancer29.8GAST, ATP4A, ATP12A
21gastric adenocarcinoma29.8S100A8, GAST
22esophageal cancer29.7ATP12A, ATP4A
23gastroesophageal reflux disease29.7GAST, ATP12A, ATP4A, S100A8
24achalasia29.6ATP4A, GAST, ATP12A
25asthma29.0S100A8, IL5, ATP12A, ATP4A
26duodenal obstruction11.1
27duodenal atresia10.9
28pancreatitis10.9
29annular pancreas10.6
30familial adenomatous polyposis10.6
31somatostatinoma10.6
32duodenal somatostatinoma10.6
33gastric cancer10.5
34aneurysm10.5
35duodenal gastrinoma10.5
36acute pancreatitis10.5
37adenocarcinoma10.5
38aortic aneurysm10.5
39ileus10.4
40celiac disease10.4
41gastrointestinal stromal tumor10.4
42abdominal aortic aneurysm10.4
43zollinger-ellison syndrome10.4
44situs inversus10.4
45gastroduodenitis10.4
46blindness10.4
47pancreatic cancer10.4
48superior mesenteric artery syndrome10.4
49duodenal disease10.4
50chronic duodenal ileus10.4

Graphical network of the top 20 diseases related to Duodenitis:



Diseases related to duodenitis

Symptoms for Duodenitis

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Drugs & Therapeutics for Duodenitis

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Drug clinical trials:

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Genetic Tests for Duodenitis

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Anatomical Context for Duodenitis

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MalaCards organs/tissues related to Duodenitis:

32
Pancreas, Colon, Testes, Liver, Small intestine, T cells, Lymph node, Lung, Kidney, Breast, Thyroid, Heart, Bone, Myeloid, B cells, Endothelial, Pancreatic islet, Neutrophil, Bone marrow, Skin, Ovary, Spleen, Smooth muscle, Monocytes, Pituitary

Animal Models for Duodenitis or affiliated genes

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MGI Mouse Phenotypes related to Duodenitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.3GAST, IL5, INS, ATP4A
2MP:00053817.6GAST, IL5, INS, ATP12A, ATP4A
3MP:00053767.4ATP4A, ATP12A, INS, IL5, GAST

Publications for Duodenitis

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Articles related to Duodenitis:

(show top 50)    (show all 2630)
idTitleAuthorsYear
1
Closure of a perforated duodenal ulcer by over-the-scope clip. (25028271)
2014
2
Acute segmentary ulcerative duodenitis induced by Streptococcus pyogenes mimicking inflammatory bowel disease. (23994254)
2013
3
Proximal duodenal obstruction--Bouveret's syndrome revisited. (23945924)
2013
4
Endoscopic submucosal dissection of a duodenal neuroendocrine tumor. (24368076)
2013
5
Acute mesenteric ischemia and duodenal ulcer perforation: a unique double pathology. (23110681)
2012
6
Association of genetic polymorphisms in IL17A and IL17F with gastro-duodenal diseases. (23012664)
2012
7
Duodenal gastrinoma with multiple gastric neuroendocrine tumors secondary to chronic Helicobacter pylori gastritis. (22588069)
2012
8
Severe duodenal involvement in familial adenomatous polyposis treated by pylorus-preserving pancreaticoduodenectomy. (22311120)
2012
9
Isolated Russell body duodenitis. (21234686)
2011
10
Superior mesenteric artery syndrome: risk factor for duodenal involvement in Henoch-SchAPnlein purpura. (21129122)
2011
11
Atherosclerosis and acetylsalicylic acid are independent risk factors for hemorrhage in patients with gastric or duodenal ulcer. (21220246)
2011
12
An unusual case of ulcerative duodenitis. (21722640)
2011
13
Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch. (20492663)
2010
14
Hemorrhagic gastritis and duodenitis following celiac plexus neurolysis. (19935986)
2009
15
Bleeding duodenal ulcer with a right upper quadrant mass. (18268056)
2008
16
Interleukin-1beta gene polymorphism as a predictor of eradication treatment efficacy in gastric and duodenal ulcer associated with Helicobacter pylori]. (19145908)
2008
17
Toll-like receptor (TLR2, TLR4 and TLR5) gene polymorphisms and Helicobacter pylori infection in children with and without duodenal ulcer. (18809506)
2008
18
High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model. (17868414)
2007
19
Unexpected superimposition of nutcracker effect in various conditions: is it an unrecognized confounding factor? Comment on: Henoch-Schonlein purpura presenting duodenal involvement similar to superior mesenteric artery syndrome in a girl. (Eur J Pediatr. 2006 Sep 29; [Epub ahead of print]). (17180389)
2007
20
Duodenal switch operation for pathologic transpyloric duodenogastric reflux. (17245178)
2007
21
Pyloric obstruction, duodenal dilatation, and extrahepatic cholestasis: a neonatal triad suggesting multiple intestinal atresias. (17011287)
2006
22
Duodenal and gastric Dieulafoy's lesions in a patient with type 2A von Willebrand's disease. (15729257)
2005
23
A long-term survival case with multiple liver metastases from duodenal gastrointestinal stromal tumor that was drastically reduced by the treatment with imatinib]. (16315926)
2005
24
Duodeno-jejunal anastomosis with trans anastomotic nasojejunal tube for congenital duodenal obstruction. (15951892)
2005
25
Decreased epithelial cytokine responses in the duodenal mucosa of Helicobacter pylori-infected duodenal ulcer patients. (12522049)
2003
26
Embolization of a duodenal arteriovenous malformation in hereditary hemorrhagic telangiectasia: case report and review of the literature. (14631462)
2003
27
Different effect of antiulcer agents on rat cysteamine-induced duodenal ulcer after sialoadenectomy, but not gastrectomy. (14512101)
2003
28
Jejunoileal bypass changes the duodenal cholecystokinin and somatostatin cell density. (12935359)
2003
29
The sixth decision regarding perforated duodenal ulcer. (12500837)
2002
30
Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas. (11744604)
2002
31
14C urea breath test does not predict density of Helicobacter pylori in duodenal ulcer disease. (11558321)
2001
32
Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humans. (10764704)
2000
33
Intraductal secretin test is as useful as duodenal secretin test in assessing exocrine pancreatic function. (9073129)
1997
34
Presence of the cagA gene in the majority of Helicobacter pylori strains is independent of whether the individual has duodenal ulcer or asymptomatic gastritis. (9398887)
1996
35
Helicobacter pylori and duodenal ulcer: evidence for a histamine pathways-involving link. (8931414)
1996
36
Human giardiasis. A morphometric study of duodenal biopsy specimens in relation to the trophozoite count in the duodenal aspirate. (8080358)
1994
37
Paroxysmal nocturnal hemoglobinuria associated with venous thrombosis and papillary endothelial hyperplasia presenting as ulcerated duodenal mass. (8060237)
1994
38
Effect of duodenal switch procedure on gastric acid production, intragastric pH, gastric emptying, and gastrointestinal hormones. (1733373)
1992
39
Patients with duodenitis have gastric secretory and motor functions like those of duodenal ulcer patients: results of a short-term treatment with ranitidine. (2066545)
1991
40
Ceruloplasmin activity in blood serum in stomach and duodenal ulcers]. (1966196)
1990
41
Outcome of ulcer-associated duodenitis after short-term medical treatment. (4006645)
1985
42
Morphological aspects of duodenitis. (6962534)
1982
43
Value of serial sonography in the in utero detection of duodenal atresia. (7070738)
1982
44
Duodenal diaphragm associated with superior mesenteric artery syndrome. (7457748)
1981
45
Duodenal obstruction in the newborn. (5980964)
1966
46
A five-to ten-year follow-up study of the Billroth I and Billroth II (polya) operations for duodenal, gastric and gastrojejunal ulcer and gastroenterostomy with vagotomy in the treatment of duodenal ulcer. (13480410)
1957
47
Chronic duodenal ileus. (13185184)
1954
48
Duodenal obstruction in infants and children. (13079414)
1953
49
Complete duodenal obstruction in the newborn. (21020171)
1946
50
THE PRE- AND POSTOPERATIVE EMPLOYMENT OF A BRASSTIPPED GASTRODUODENAL TUBE AS AN AID IN THE SURGICAL TREATMENT OF DUODENAL OBSTRUCTION IN THE NEWBORN. (17858187)
1943

Variations for Duodenitis

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Expression for genes affiliated with Duodenitis

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Expression patterns in normal tissues for genes affiliated with Duodenitis

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Pathways for genes affiliated with Duodenitis

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Compounds for genes affiliated with Duodenitis

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Compounds related to Duodenitis according to GeneCards/GeneDecks:

(show all 34)
idCompoundScoreTop Affiliating Genes
1calcium gluconate449.9INS, GAST
2i-app449.9GAST, INS
3methacholine44 50 1111.8IL5, GAST
44-ipp619.8IL5, S100A8
5git 27619.8IL5, S100A8
6starch449.8GAST, INS
7nicotinamide44 1110.8GAST, INS
8pirfenidone44 6110.8S100A8, IL5
9erythromycin44 2 50 1112.8GAST, IL5
10as 10144 6110.8S100A8, IL5
11octreotide44 61 28 1112.7INS, GAST
12amoxicillin44 50 1111.7S100A8, GAST
13c-peptide449.7GAST, INS
14metronidazole44 1110.7GAST, S100A8
15allergens449.6S100A8, IL5
16isoproterenol44 1110.5GAST, IL5
17esomeprazole44 50 1111.5ATP4A, GAST
18rabeprazole44 50 24 1112.5GAST, ATP4A
19hydrocortisone44 2 61 1112.5GAST, IL5, INS
20thyroxine44 2410.5GAST, IL5, INS
21lansoprazole44 50 24 1112.5ATP4A, GAST
22thalidomide44 50 61 1112.3S100A8, IL5
23tetracycline44 1110.3GAST, S100A8
24clarithromycin44 1110.3IL5, S100A8, GAST
25histamine44 28 2411.2IL5, S100A8, GAST
26testosterone44 61 24 1112.2INS, IL5, GAST
27creatinine449.1GAST, S100A8, INS
28pantoprazole44 50 24 1112.0GAST, ATP12A, ATP4A
29omeprazole44 50 28 24 1112.9GAST, S100A8, ATP4A
30dexamethasone44 50 28 1111.8INS, IL5, S100A8, GAST
31glutamate448.8INS, IL5, S100A8, GAST
32serine448.7INS, IL5, S100A8, GAST
33tyrosine448.6INS, IL5, S100A8, GAST
34alanine448.6INS, S100A8, GAST

GO Terms for genes affiliated with Duodenitis

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Cellular components related to Duodenitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5GAST, S100A8, IL5, INS
2extracellular spaceGO:0056157.9S100A8, IL5, INS, ATP4A

Biological processes related to Duodenitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1wound healingGO:0420609.4S100A8, INS
2positive regulation of NF-kappaB transcription factor activityGO:0510929.4S100A8, INS
3positive regulation of peptidyl-tyrosine phosphorylationGO:0507319.3IL5, INS
4positive regulation of cell growthGO:0303079.3INS, S100A8
5ATP biosynthetic processGO:0067549.2ATP12A, ATP4A

Molecular functions related to Duodenitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.5GAST, INS
2hydrogen:potassium-exchanging ATPase activityGO:0089008.8ATP12A, ATP4A

Products for genes affiliated with Duodenitis

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Sources for Duodenitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet