MCID: DYS070
MIFTS: 26

Dysalbuminemic Hyperthyroxinemia malady

Summaries for Dysalbuminemic Hyperthyroxinemia

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46OMIM, 32MalaCards
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MalaCards: Dysalbuminemic Hyperthyroxinemia is related to hyperthyroxinemia and thyroiditis. An important gene associated with Dysalbuminemic Hyperthyroxinemia is ALB (albumin), and among its related pathways is FOXA2 and FOXA3 transcription factor networks. The compounds kebuzone and tolmetin glucuronide have been mentioned in the context of this disorder. Affiliated tissues include thyroid.

Description from OMIM:46 103600

Aliases & Classifications for Dysalbuminemic Hyperthyroxinemia

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20GeneTests, 46OMIM, 60UMLS
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Aliases & Descriptions:

dysalbuminemic hyperthyroxinemia 20 46 60


Related Diseases for Dysalbuminemic Hyperthyroxinemia

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17GeneCards, 18GeneDecks
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Diseases related to Dysalbuminemic Hyperthyroxinemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 46)
idRelated DiseaseScoreTop Affiliating Genes
1hyperthyroxinemia31.6OXA1L, ALB, SERPINA7, TTR
2thyroiditis30.9SERPINA7
3hypothyroidism30.5TTR, SERPINA7
4thyrotoxicosis30.3SERPINA7
5goiter30.3SERPINA7
6congenital hypothyroidism30.3SERPINA7
7hepatitis30.3SERPINA7, TTR
8multinodular goiter10.2
9familial hypercholesterolemia10.2
10familial hyperlipidemia10.2
11acquired immunodeficiency syndrome10.0ALB
12protein-losing enteropathy10.0ALB
13nephrotic syndrome10.0ALB
14arthritis10.0ALB
15hepatic encephalopathy10.0ALB
16malaria10.0ALB
17hyperthyroidism10.0SERPINA7
18euthyroid sick syndrome10.0SERPINA7
19graves' disease10.0SERPINA7
20pituitary adenoma10.0SERPINA7
21peritonitis10.0ALB
22metabolic acidosis10.0ALB
23hypercalcemia10.0ALB
24rheumatoid arthritis10.0OXA1L
25dental caries10.0OXA1L
26nutritional deficiency disease10.0ALB, TTR
27myocardial infarction10.0OXA1L
28protein-energy malnutrition10.0ALB, TTR
29autonomic neuropathy10.0TTR, ALB
30polyneuropathy10.0SERPINA7, TTR
31galactosemia10.0TTR, ALB
32primary hyperoxaluria10.0ALB, TTR
33asthma10.0OXA1L
34uremia10.0ALB, OXA1L
35hyperhomocysteinemia10.0TTR, ALB
36diabetes mellitus10.0OXA1L, ALB
37hepatitis b10.0OXA1L, ALB
38brain edema10.0ALB, OXA1L
39deficiency anemia10.0SERPINA7, TTR, ALB
40diabetic nephropathy10.0ALB, OXA1L
41tetanus10.0ALB, OXA1L
42type 1 diabetes10.0SERPINA7, ALB
43hepatocellular carcinoma10.0SERPINA7, OXA1L, ALB
44chronic kidney failure10.0SERPINA7, OXA1L, ALB, TTR
45sepsis10.0TTR, SERPINA7, ALB, OXA1L
46liver cirrhosis10.0TTR, ALB, SERPINA7, OXA1L

Graphical network of the top 20 diseases related to Dysalbuminemic Hyperthyroxinemia:



Diseases related to dysalbuminemic hyperthyroxinemia

Clinical Features for Dysalbuminemic Hyperthyroxinemia

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46OMIM
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Clinical features from OMIM:

103600

Drugs & Therapeutics for Dysalbuminemic Hyperthyroxinemia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Dysalbuminemic Hyperthyroxinemia

Drug clinical trials:

Search ClinicalTrials for Dysalbuminemic Hyperthyroxinemia

Search NIH Clinical Center for Dysalbuminemic Hyperthyroxinemia

Search CenterWatch for Dysalbuminemic Hyperthyroxinemia

Genetic Tests for Dysalbuminemic Hyperthyroxinemia

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20GeneTests
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Genetic tests related to Dysalbuminemic Hyperthyroxinemia:

id Genetic test Affiliating Genes
1 Dysalbuminemic Hyperthyroxinemia20 ALB

Anatomical Context for Dysalbuminemic Hyperthyroxinemia

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32MalaCards
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MalaCards organs/tissues related to Dysalbuminemic Hyperthyroxinemia:

32
Thyroid

Animal Models for Dysalbuminemic Hyperthyroxinemia or affiliated genes

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Publications for Dysalbuminemic Hyperthyroxinemia

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Genetic Variations for Dysalbuminemic Hyperthyroxinemia

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Expression for genes affiliated with Dysalbuminemic Hyperthyroxinemia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dysalbuminemic Hyperthyroxinemia

Search GEO for disease gene expression data for Dysalbuminemic Hyperthyroxinemia.

Pathways for genes affiliated with Dysalbuminemic Hyperthyroxinemia

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37NCBI BioSystems Database
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Pathways related to Dysalbuminemic Hyperthyroxinemia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1ALB, TTR

Compounds for genes affiliated with Dysalbuminemic Hyperthyroxinemia

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Sources:
44Novoseek, 11DrugBank, 59Tocris Bioscience, 49PharmGKB, 28IUPHAR, 24HMDB
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Compounds related to Dysalbuminemic Hyperthyroxinemia according to GeneCards/GeneDecks:

(show top 50)    (show all 94)
idCompoundScoreTop Affiliating Genes
1kebuzone449.9ALB, OXA1L
2tolmetin glucuronide449.9OXA1L, ALB
3azapropazone44 1110.8ALB, OXA1L
4sodium octanoate449.8ALB, OXA1L
5pirprofen449.8ALB, OXA1L
6dansylsarcosine449.8OXA1L, ALB
7rhsa449.8ALB, OXA1L
8acetyldigitoxin44 1110.8ALB, OXA1L
9hhpa449.8OXA1L, ALB
10dansylamide44 1110.8ALB, OXA1L
11eprex449.8OXA1L, ALB
12(s)-ketoprofen449.8OXA1L, ALB
13polyvinylpyrrolidone449.8ALB, OXA1L
14sulfisoxazole44 59 49 1112.8ALB, OXA1L
15fenoprofen28 44 1111.8ALB, OXA1L
16oxyphenbutazone44 1110.8OXA1L, ALB
17cyclosarin449.8OXA1L, ALB
18polyvinyl alcohol449.8OXA1L, ALB
19indoxyl sulfate449.8OXA1L, ALB
20n(epsilon)-(carboxymethyl)lysine449.8ALB, OXA1L
21tolmetin44 1110.7OXA1L, ALB
22cefoperazone44 1110.7ALB, OXA1L
23tween 80449.7OXA1L, ALB
24aopp449.7ALB, OXA1L
25decanoic acid44 28 1111.7OXA1L, ALB
26octanoate449.7ALB, OXA1L
27suprofen44 1110.6ALB, OXA1L
28hydroxyethyl starch449.6OXA1L, ALB
29idpn449.6ALB, TTR
30phenylbutazone44 1110.5ALB, OXA1L
318-anilino-1-naphthalenesulfonic acid449.4TTR, OXA1L
32enflurane44 1110.3OXA1L, ALB
33deae449.3OXA1L, TTR
34furosemide44 49 59 28 11 2414.2ALB, SERPINA7, OXA1L
35phenytoin44 49 28 1112.2OXA1L, SERPINA7, ALB
36chloroform449.1OXA1L, TTR
37flurbiprofen44 28 49 1112.0ALB, TTR, OXA1L
38glutaraldehyde449.0ALB, TTR, OXA1L
39Levothyroxine119.0TTR, ALB, SERPINA7
40Liotrix119.0ALB, TTR, SERPINA7
41Liothyronine11 249.9TTR, SERPINA7, ALB
42diclofenac44 28 49 1111.9TTR, SERPINA7, ALB
43urea44 11 2410.8ALB, TTR, SERPINA7
44pcbs448.7TTR, SERPINA7
45vitamin a44 11 2410.6TTR, SERPINA7, ALB
46aspirin44 49 28 2411.5TTR, SERPINA7, OXA1L
47diflunisal44 119.4TTR, OXA1L, SERPINA7, ALB
48salicylic acid44 289.4SERPINA7, OXA1L, TTR, ALB
49sodium dodecylsulfate448.4SERPINA7, OXA1L, TTR, ALB
50thyroxine44 249.4TTR, SERPINA7, ALB, OXA1L

GO Terms for genes affiliated with Dysalbuminemic Hyperthyroxinemia

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16Gene Ontology
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Cellular components related to Dysalbuminemic Hyperthyroxinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5ALB, SERPINA7, TTR
2protein complexGO:0432348.3ALB, TTR, OXA1L

Molecular functions related to Dysalbuminemic Hyperthyroxinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone bindingGO:0425629.0SERPINA7, TTR

Products for genes affiliated with Dysalbuminemic Hyperthyroxinemia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dysalbuminemic Hyperthyroxinemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet