MCID: DYS070
MIFTS: 21

Dysalbuminemic Hyperthyroxinemia

Categories: Genetic diseases

Aliases & Classifications for Dysalbuminemic Hyperthyroxinemia

MalaCards integrated aliases for Dysalbuminemic Hyperthyroxinemia:

Name: Dysalbuminemic Hyperthyroxinemia 24 69

Classifications:



Summaries for Dysalbuminemic Hyperthyroxinemia

MalaCards based summary : Dysalbuminemic Hyperthyroxinemia is related to hyperthyroxinemia, familial dysalbuminemic and hyperthyroxinemia. An important gene associated with Dysalbuminemic Hyperthyroxinemia is ALB (Albumin), and among its related pathways/superpathways are Insulin secretion and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include thyroid and testes.

Related Diseases for Dysalbuminemic Hyperthyroxinemia

Diseases in the Dysalbuminemic Hyperthyroxinemia family:

Hyperthyroxinemia, Familial Dysalbuminemic

Diseases related to Dysalbuminemic Hyperthyroxinemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
id Related Disease Score Top Affiliating Genes
1 hyperthyroxinemia, familial dysalbuminemic 11.9
2 hyperthyroxinemia 10.9
3 thyroiditis 10.4
4 midface dysplasia 10.2 ALB TTR
5 hypothyroidism 10.1
6 cataract 10.1 ALB TTR
7 male genital organ stricture 10.1 ALB TTR
8 female infertility of uterine origin 10.1 ALB TTR
9 speech and communication disorders 10.1 ALB TTR
10 milker's nodule 10.1 ALB TTR
11 motion sickness 10.1 ALB TTR
12 hemopericardium 10.1 ALB TTR
13 spastic entropion 10.0 ALB TTR
14 bladder sarcoma 10.0 ALB TTR
15 congenital nonspherocytic hemolytic anemia 10.0 ALB SERPINA7
16 thyroid hormone resistance 10.0
17 hepatitis 10.0
18 congenital hypothyroidism 10.0
19 multinodular goiter 10.0
20 goiter 10.0
21 infertility 10.0 ALB TTR
22 sleep disorder 10.0 ALB TTR
23 mediastinum leiomyoma 9.9 ALB TTR
24 paranasal sinus sarcoma 9.9 ALB TTR
25 kozlowski brown hardwick syndrome 9.8 ALB OXA1L
26 survival motor neuron spinal muscular atrophy 9.8 ALB TTR
27 chronic myelomonocytic leukemia 9.8 ALB TTR
28 anogenital venereal wart 9.7 ALB TTR
29 hemoglobinopathy 9.5 ALB SERPINA7 TTR
30 prostate carcinoma in situ 9.5 ALB TTR
31 microcephaly 8, primary, autosomal recessive 9.3 ALB OXA1L TTR
32 early-onset severe reducing body myopathy, x-linked 8.7 ALB OXA1L SERPINA7 TTR

Graphical network of the top 20 diseases related to Dysalbuminemic Hyperthyroxinemia:



Diseases related to Dysalbuminemic Hyperthyroxinemia

Symptoms & Phenotypes for Dysalbuminemic Hyperthyroxinemia

Drugs & Therapeutics for Dysalbuminemic Hyperthyroxinemia

Search Clinical Trials , NIH Clinical Center for Dysalbuminemic Hyperthyroxinemia

Genetic Tests for Dysalbuminemic Hyperthyroxinemia

Genetic tests related to Dysalbuminemic Hyperthyroxinemia:

id Genetic test Affiliating Genes
1 Dysalbuminemic Hyperthyroxinemia 24 ALB

Anatomical Context for Dysalbuminemic Hyperthyroxinemia

MalaCards organs/tissues related to Dysalbuminemic Hyperthyroxinemia:

39
Thyroid, Testes

Publications for Dysalbuminemic Hyperthyroxinemia

Articles related to Dysalbuminemic Hyperthyroxinemia:

(show top 50) (show all 59)
id Title Authors Year
1
Familial Dysalbuminemic Hyperthyroxinemia that was Inappropriately Treated with Thiamazole Due to Pseudo-thyrotoxic Symptoms. ( 28781323 )
2017
2
SEVEN FAMILIAL DYSALBUMINEMIC HYPERTHYROXINEMIA CASES IN THREE UNRELATED JAPANESE FAMILIES AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ANALYSIS OF THE THYROXINE BINDING PROFILE. ( 28816534 )
2017
3
First Report of Familial Dysalbuminemic Hyperthyroxinemia With an ALB Variant. ( 27834068 )
2017
4
A case of familial dysalbuminemic hyperthyroxinemia (FDH) in Japan: FDH as a possible differential diagnosis of syndrome of inappropriate secretion of thyroid-stimulating hormone (SITSH). ( 27904073 )
2016
5
Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia. ( 26777880 )
2016
6
Familial Dysalbuminemic Hyperthyroxinemia in a Japanese Man Caused by a Point Albumin Gene Mutation (R218P). ( 27081329 )
2016
7
A novel mutation in the Albumin gene (R218S) causing familial dysalbuminemic hyperthyroxinemia in a family of Bangladeshi extraction. ( 24494774 )
2014
8
Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading. ( 25153218 )
2014
9
A novel albumin gene mutation (R222I) in familial dysalbuminemic hyperthyroxinemia. ( 24646103 )
2014
10
Spuriously high free thyroxine values in familial dysalbuminemic hyperthyroxinemia. ( 21149501 )
2011
11
Familial dysalbuminemic hyperthyroxinemia: a persistent diagnostic challenge. ( 19282355 )
2009
12
Artifactually elevated serum-free thyroxine levels measured by equilibrium dialysis in a pregnant woman with familial dysalbuminemic hyperthyroxinemia. ( 15068631 )
2004
13
Structural basis of albumin-thyroxine interactions and familial dysalbuminemic hyperthyroxinemia. ( 12743361 )
2003
14
Familial dysalbuminemic hyperthyroxinemia: a rare example of albumin polymorphism and its rapid molecular diagnosis. ( 12099390 )
2002
15
Congenital hypothyroidism in a child with unsuspected familial dysalbuminemic hyperthyroxinemia caused by a mutation (R218H) in the human albumin gene. ( 11743520 )
2001
16
Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine. ( 10946882 )
2000
17
A point mutation in the albumin gene in a Chinese patient with familial dysalbuminemic hyperthyroxinemia. ( 10526251 )
1999
18
Structural investigations of a new familial dysalbuminemic hyperthyroxinemia genotype. ( 10430791 )
1999
19
A novel missense mutation in codon 218 of the albumin gene in a distinct phenotype of familial dysalbuminemic hyperthyroxinemia in a Japanese kindred. ( 9329347 )
1997
20
Mutations in a specific human serum albumin thyroxine binding site define the structural basis of familial dysalbuminemic hyperthyroxinemia. ( 8702585 )
1996
21
Inhibition of serum protein binding of thyroxine in a hypothyroid patient with familial dysalbuminemic hyperthyroxinemia. ( 8929830 )
1996
22
Familial dysalbuminemic hyperthyroxinemia and thyroid hormone autoantibodies: interference in current free thyroid hormone assays. ( 8964572 )
1996
23
Identification of a human serum albumin species associated with familial dysalbuminemic hyperthyroxinemia. ( 7852505 )
1995
24
Familial dysalbuminemic hyperthyroxinemia in pregnancy. ( 8548059 )
1995
25
Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred. ( 7829599 )
1995
26
Familial dysalbuminemic hyperthyroxinemia: cumulative experience in 29 consecutive patients. ( 15251607 )
1995
27
An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families. ( 8048949 )
1994
28
Postpartum thyroiditis and familial dysalbuminemic hyperthyroxinemia. ( 8288714 )
1994
29
Fluorescence investigations of albumin from patients with familial dysalbuminemic hyperthyroxinemia. ( 8475173 )
1993
30
Free thyroxine measured by the Ciba Corning ACS-180 on samples from patients with familial dysalbuminemic hyperthyroxinemia. ( 8353971 )
1993
31
The effects of danazol on a patient with familial dysalbuminemic hyperthyroxinemia. ( 8422721 )
1993
32
Prevalence of familial dysalbuminemic hyperthyroxinemia in serum samples received for thyroid testing. ( 1868606 )
1991
33
Familial dysalbuminemic hyperthyroxinemia associated with multinodular goiter and elevated radioiodine uptake. A case report. ( 1769174 )
1991
34
Diagnosis of familial dysalbuminemic hyperthyroxinemia and investigation of the nature of the variant albumin. ( 2135643 )
1990
35
Elevated thyroxine and free thyroxine in euthyroid patients: familial dysalbuminemic hyperthyroxinemia. ( 2109350 )
1990
36
Can the type of variant albumin in familial dysalbuminemic hyperthyroxinemia be determined by measuring iodothyronines in serum? ( 2253589 )
1990
37
Studies on the nature of iodothyronine binding in familial dysalbuminemic hyperthyroxinemia. ( 2370303 )
1990
38
Thyroxin binding by human serum albumin after denaturation of the thyroxin-binding globulin in familial dysalbuminemic hyperthyroxinemia. ( 3129213 )
1988
39
Coexistence of familial dysalbuminemic hyperthyroxinemia with familial hypercholesterolemia and multiple lipoprotein type hyperlipidemia. ( 3407659 )
1988
40
Familial dysalbuminemic hyperthyroxinemia in a Hispanic family. ( 3341680 )
1988
41
Free thyroxin in familial dysalbuminemic hyperthyroxinemia, as measured by five assays. ( 3349617 )
1988
42
Normal cellular uptake of thyroxine from serum of patients with familial dysalbuminemic hyperthyroxinemia or elevated thyroxine-binding globulin. ( 3142912 )
1988
43
A four generation study of familial dysalbuminemic hyperthyroxinemia: diagnosis in the presence of an acquired excess of thyroxine-binding globulin. ( 3110251 )
1987
44
Role of serum carrier proteins in the peripheral metabolism and tissue distribution of thyroid hormones in familial dysalbuminemic hyperthyroxinemia and congenital elevation of thyroxine-binding globulin. ( 3112186 )
1987
45
Familial dysalbuminemic hyperthyroxinemia associated with primary thyroid disease. ( 3812513 )
1987
46
Familial dysalbuminemic hyperthyroxinemia. ( 3111180 )
1987
47
Prevalence of familial dysalbuminemic hyperthyroxinemia in Hispanics. ( 3662294 )
1987
48
Modulation of thyroid parameters by exogenous thyroxine in familial dysalbuminemic hyperthyroxinemia. ( 3081779 )
1986
49
Sex hormone-binding protein in hyperthyroxinemic patients: a discriminator for thyroid status in thyroid hormone resistance and familial dysalbuminemic hyperthyroxinemia. ( 3084540 )
1986
50
Hepatic bioavailability of thyroxine and testosterone in familial dysalbuminemic hyperthyroxinemia. ( 4031018 )
1985

Variations for Dysalbuminemic Hyperthyroxinemia

Expression for Dysalbuminemic Hyperthyroxinemia

Search GEO for disease gene expression data for Dysalbuminemic Hyperthyroxinemia.

Pathways for Dysalbuminemic Hyperthyroxinemia

Pathways related to Dysalbuminemic Hyperthyroxinemia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.2 ALB SERPINA7 TTR
2 10.6 ALB TTR

GO Terms for Dysalbuminemic Hyperthyroxinemia

Cellular components related to Dysalbuminemic Hyperthyroxinemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein complex GO:0043234 8.8 ALB OXA1L TTR

Biological processes related to Dysalbuminemic Hyperthyroxinemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.96 ALB TTR
2 thyroid hormone transport GO:0070327 8.62 SERPINA7 TTR

Sources for Dysalbuminemic Hyperthyroxinemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....