MCID: DYS004
MIFTS: 27

Dyscalculia malady

Neuronal category

Summaries for Dyscalculia

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A learning disability involving a math disability can cause such difficulties as learning math concepts (such as quantity, place value, and time), difficulty memorizing math facts, difficulty organizing numbers, and understanding how problems are organized on the page.

MalaCards: Dyscalculia, also known as developmental arithmetic disorder, is related to dyslexia and gerstmann syndrome. An important gene associated with Dyscalculia is GYLTL1B (glycosyltransferase-like 1B), and among its related pathways is Platelet activation, signaling and aggregation. Affiliated tissues include brain, parietal lobe and temporal lobe.

Wikipedia:64 Dyscalculia is difficulty in learning or comprehending arithmetic, such as difficulty in understanding... more...

Aliases & Classifications for Dyscalculia

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

dyscalculia 8 10
developmental arithmetic disorder 61
disorder of arithmetical skills 8
mathematics disorder 8


External Ids:

Disease Ontology8 DOID:12568
ICD1025 F81.2

Related Diseases for Dyscalculia

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Dyscalculia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1dyslexia10.5
2gerstmann syndrome10.1
3alzheimer's disease10.0
4dysgraphia10.0
5turner syndrome10.0
6char syndrome10.0
7memory impairment10.0

Graphical network of diseases related to Dyscalculia:



Diseases related to dyscalculia

Clinical Features for Dyscalculia

Drugs & Therapeutics for Dyscalculia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Dyscalculia

Drug clinical trials:

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Search NIH Clinical Center for Dyscalculia

Search CenterWatch for Dyscalculia

Genetic Tests for Dyscalculia

Anatomical Context for Dyscalculia

Sources:
33MalaCards
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MalaCards organs/tissues related to Dyscalculia:

33
Brain, Parietal lobe, Temporal lobe

Animal Models for Dyscalculia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Dyscalculia

Sources:
51PubMed
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Articles related to Dyscalculia:

(show top 50)    (show all 117)
idTitleAuthorsYear
1
Developmental dyscalculia is related to visuo-spatial memory and inhibition impairment. (23890692)
2013
2
Dyscalculia from a developmental and differential perspective. (23970870)
2013
3
Do subitizing deficits in developmental dyscalculia involve pattern recognition weakness? (23278925)
2013
4
Residual number processing in dyscalculia. (24266008)
2013
5
A case study of arithmetic facts dyscalculia caused by a hypersensitivity-to-interference in memory. (22321390)
2013
6
Symbolic and non symbolic numerical representation in adults with and without developmental dyscalculia. (23190433)
2012
7
Time-Resolved and Spatio-Temporal Analysis of Complex Cognitive Processes and their Role in Disorders like Developmental Dyscalculia. (22368322)
2012
8
Dyscalculia: awareness and student support. (23035381)
2012
9
Cognitive inhibition in students with and without dyslexia and dyscalculia. (22522204)
2012
10
The diagnosis and management of dyscalculia. (23227129)
2012
11
Inhibitory ability of children with developmental dyscalculia. (21336738)
2011
12
Dyscalculia: from brain to education. (21617068)
2011
13
The "where" and "what" in developmental dyscalculia. (21955112)
2011
14
Developmental Changes in the Profiles of Dyscalculia: An Explanation Based on a Double Exact-and-Approximate Number Representation Model. (22203797)
2011
15
Impaired acuity of the approximate number system underlies mathematical learning disability (dyscalculia). (21679173)
2011
16
Time processing in dyscalculia. (22194731)
2011
17
Attentional networks in developmental dyscalculia. (20157427)
2010
18
Developmental trajectory of number acuity reveals a severe impairment in developmental dyscalculia. (20381023)
2010
19
Symbolic and nonsymbolic number comparison in children with and without dyscalculia. (20149355)
2010
20
Developmental dyscalculia: compensatory mechanisms in left intraparietal regions in response to nonsymbolic magnitudes. (19653919)
2009
21
Dysfunctional neural network of spatial working memory contributes to developmental dyscalculia. (19540861)
2009
22
Neuroanatomical correlates of developmental dyscalculia: combined evidence from morphometry and tractography. (20046827)
2009
23
Dyscalculia: neuroscience and education. (21258625)
2008
24
Emotional and behavioral characteristics over a six-year period in youths with persistent and nonpersistent dyscalculia. (18434292)
2008
25
Core information processing deficits in developmental dyscalculia and low numeracy. (18801122)
2008
26
Are dyslexia and dyscalculia associated with Rolandic epilepsy? A short report on ten Italian patients. (18077230)
2007
27
Virtual dyscalculia induced by parietal-lobe TMS impairs automatic magnitude processing. (17379521)
2007
28
Number development and developmental dyscalculia. (17979867)
2007
29
Memory abilities in children with subtypes of dyscalculia. (17083294)
2006
30
Principles underlying the design of "The Number Race", an adaptive computer game for remediation of dyscalculia. (16734905)
2006
31
ADHD and dyscalculia: Evidence for independent familial transmission. (15727331)
2005
32
Automatic activation of internal magnitudes: a study of developmental dyscalculia. (16187882)
2005
33
The role of semantic and symbolic representations in arithmetic processing: insights from simulated dyscalculia in a connectionist model. (15174483)
2004
34
Functional and structural alterations of the intraparietal sulcus in a developmental dyscalculia of genetic origin. (14622587)
2003
35
A systematic procedure for identifying and classifying children with dyscalculia among primary school children in India. (12067188)
2002
36
More evidence for the role of the central executive in retrieving arithmetic facts - a case study of severe developmental dyscalculia. (11992213)
2002
37
Developmental dyscalculia. (11516606)
2001
38
Attentional function as measured by a Continuous Performance Task in children with dyscalculia. (11718231)
2001
39
Regional metabolism: associations with dyscalculia in Alzheimer's disease. (9854970)
1998
40
Profound developmental dyscalculia: evidence for a cardinal/ordinal skills acquisition device. (9356161)
1997
41
Remediation of arabic numeral processing in a case of developmental dyscalculia. (22106861)
1996
42
Dyscalculia and dyslexia after right hemisphere injury in infancy. (8599565)
1996
43
Developmental dyscalculia behavioral and attentional aspects: a research note. (8847384)
1995
44
Developmental dyscalculia and brain laterality. (7555012)
1995
45
Developmental dyscalculia in children: review of the literature and clinical validation. (7521556)
1994
46
Children with developmental dyscalculia. (1592200)
1992
47
Perceptual-motor and attentional correlates of developmental dyscalculia. (2774508)
1989
48
Developmental dyscalculia. (2464456)
1988
49
Developmental dyscalculia. (4174924)
1968
50
Dyscalculia. (13694482)
1961

Genetic Variations for Dyscalculia

Expression for genes affiliated with Dyscalculia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyscalculia

Search GEO for disease gene expression data for Dyscalculia.

Pathways for genes affiliated with Dyscalculia

Sources:
54Reactome
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Pathways related to Dyscalculia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.2ADRA2A, SLC7A11

Compounds for genes affiliated with Dyscalculia

GO Terms for genes affiliated with Dyscalculia

Sources:
16Gene Ontology
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Biological processes related to Dyscalculia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ion transportGO:0068119.0SLC7A11, GLRA2

Products for genes affiliated with Dyscalculia

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Sources for Dyscalculia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet