MCID: DYS004
MIFTS: 28

Dyscalculia malady

Neuronal diseases category

Summaries for Dyscalculia

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A learning disability involving a math disability can cause such difficulties as learning math concepts (such as quantity, place value, and time), difficulty memorizing math facts, difficulty organizing numbers, and understanding how problems are organized on the page.

MalaCards: Dyscalculia, also known as developmental arithmetic disorder, is related to dyslexia and learning disability. An important gene associated with Dyscalculia is GYLTL1B (glycosyltransferase-like 1B), and among its related pathways is Platelet activation, signaling and aggregation. Affiliated tissues include brain, eye and parietal lobe.

Wikipedia:63 Dyscalculia is difficulty in learning or comprehending arithmetic, such as difficulty in understanding... more...

Aliases & Classifications for Dyscalculia

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

dyscalculia 8 10
developmental arithmetic disorder 60
disorder of arithmetical skills 8
mathematics disorder 8


External Ids:

Disease Ontology8 DOID:12568
ICD1025 F81.2

Related Diseases for Dyscalculia

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Dyscalculia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1dyslexia10.4
2learning disability10.3
3alzheimer's disease10.2
4gerstmann syndrome10.1
5cerebritis10.0
6dysgraphia10.0
7turner syndrome10.0
8developmental disabilities10.0

Graphical network of diseases related to Dyscalculia:



Diseases related to dyscalculia

Clinical Features for Dyscalculia

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Drugs & Therapeutics for Dyscalculia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Dyscalculia

Drug clinical trials:

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Search NIH Clinical Center for Dyscalculia

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Genetic Tests for Dyscalculia

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Anatomical Context for Dyscalculia

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Sources:
32MalaCards
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MalaCards organs/tissues related to Dyscalculia:

32
Brain, Eye, Parietal lobe

Animal Models for Dyscalculia or affiliated genes

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Publications for Dyscalculia

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Sources:
50PubMed
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Articles related to Dyscalculia:

(show top 50)    (show all 117)
idTitleAuthorsYear
1
Developmental dyscalculia is related to visuo-spatial memory and inhibition impairment. (23890692)
2013
2
Mathematical difficulties in nonverbal learning disability or co-morbid dyscalculia and dyslexia. (23971493)
2013
3
Developmental dyscalculia. (23622170)
2013
4
Do subitizing deficits in developmental dyscalculia involve pattern recognition weakness? (23278925)
2013
5
The link between logic, mathematics and imagination: evidence from children with developmental dyscalculia and mathematically gifted children. (23786472)
2013
6
Residual number processing in dyscalculia. (24266008)
2013
7
Parietal variant Alzheimer's disease presenting with dyscalculia. (22710700)
2013
8
The frequency of dyscalculia among primary school children. (23793282)
2013
9
Dyscalculia: Number games. (23302840)
2013
10
A case study of arithmetic facts dyscalculia caused by a hypersensitivity-to-interference in memory. (22321390)
2013
11
Operational momentum effect in children with and without developmental dyscalculia. (24273526)
2013
12
"You can nurse with dyscalculia--but know your limitations". (23035379)
2012
13
Does attentional training improve numerical processing in developmental dyscalculia? (22081984)
2012
14
Symbolic and non symbolic numerical representation in adults with and without developmental dyscalculia. (23190433)
2012
15
Time-Resolved and Spatio-Temporal Analysis of Complex Cognitive Processes and their Role in Disorders like Developmental Dyscalculia. (22368322)
2012
16
The diagnosis and management of dyscalculia. (23227129)
2012
17
Mental number line training in children with developmental dyscalculia. (21295145)
2011
18
The "where" and "what" in developmental dyscalculia. (21955112)
2011
19
Processing ordinality and quantity: the case of developmental dyscalculia. (21935374)
2011
20
Relationships between number and space processing in adults with and without dyscalculia. (21802651)
2011
21
Foundational numerical capacities and the origins of dyscalculia. (20971676)
2010
22
Mathematics anxiety in children with developmental dyscalculia. (20633269)
2010
23
Attention, automaticity, and developmental dyscalculia. (19586217)
2009
24
Dysfunctional neural network of spatial working memory contributes to developmental dyscalculia. (19540861)
2009
25
Neuroanatomical correlates of developmental dyscalculia: combined evidence from morphometry and tractography. (20046827)
2009
26
Dyscalculia: neuroscience and education. (21258625)
2008
27
Emotional and behavioral characteristics over a six-year period in youths with persistent and nonpersistent dyscalculia. (18434292)
2008
28
Core information processing deficits in developmental dyscalculia and low numeracy. (18801122)
2008
29
Virtual dyscalculia induced by parietal-lobe TMS impairs automatic magnitude processing. (17379521)
2007
30
Dyscalculia. (18029243)
2007
31
Impaired parietal magnitude processing in developmental dyscalculia. (18088583)
2007
32
Number development and developmental dyscalculia. (17979867)
2007
33
Memory abilities in children with subtypes of dyscalculia. (17083294)
2006
34
Principles underlying the design of "The Number Race", an adaptive computer game for remediation of dyscalculia. (16734905)
2006
35
ADHD and dyscalculia: Evidence for independent familial transmission. (15727331)
2005
36
Developmental dyscalculia: a prospective six-year follow-up. (15707235)
2005
37
The role of semantic and symbolic representations in arithmetic processing: insights from simulated dyscalculia in a connectionist model. (15174483)
2004
38
Functional and structural alterations of the intraparietal sulcus in a developmental dyscalculia of genetic origin. (14622587)
2003
39
Acalculia and dyscalculia. (12539968)
2002
40
A systematic procedure for identifying and classifying children with dyscalculia among primary school children in India. (12067188)
2002
41
More evidence for the role of the central executive in retrieving arithmetic facts - a case study of severe developmental dyscalculia. (11992213)
2002
42
Dyslexia Dysorthography Dyscalculia: Review of the scientific data (21348173)
2000
43
Understanding dissociations in dyscalculia: a brain imaging study of the impact of number size on the cerebral networks for exact and approximate calculation. (11050024)
2000
44
Dyscalculia in the early stages of Alzheimer's disease. (10100960)
1999
45
Profound developmental dyscalculia: evidence for a cardinal/ordinal skills acquisition device. (9356161)
1997
46
Remediation of arabic numeral processing in a case of developmental dyscalculia. (22106861)
1996
47
Developmental dyscalculia behavioral and attentional aspects: a research note. (8847384)
1995
48
Dyslexia and dyscalculia in children--risks, early precursors, bottlenecks and cognitive mechanisms. (8079640)
1994
49
Theory-based assessment of acquired dyscalculia. (1799455)
1991
50
Developmental dyscalculia. (4174924)
1968

Genetic Variations for Dyscalculia

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Expression for genes affiliated with Dyscalculia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyscalculia

Search GEO for disease gene expression data for Dyscalculia.

Pathways for genes affiliated with Dyscalculia

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Sources:
53Reactome
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Pathways related to Dyscalculia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.2ADRA2A, SLC7A11

Compounds for genes affiliated with Dyscalculia

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GO Terms for genes affiliated with Dyscalculia

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Sources:
16Gene Ontology
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Biological processes related to Dyscalculia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ion transportGO:0068119.0SLC7A11, GLRA2

Products for genes affiliated with Dyscalculia

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Sources for Dyscalculia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet