MCID: DYS006
MIFTS: 35

Dysembryoplastic Neuroepithelial Tumor malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Dysembryoplastic Neuroepithelial Tumor

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Aliases & Descriptions for Dysembryoplastic Neuroepithelial Tumor:

Name: Dysembryoplastic Neuroepithelial Tumor 11 46 13 52 66
Dysembryoplastic Neuroepithelial Neoplasm 11
 
Dnet 52

Characteristics:

Orphanet epidemiological data:

52
dysembryoplastic neuroepithelial tumor:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:2679
NCIt43 C9505
Orphanet52 ORPHA251946
UMLS via Orphanet67 C1266177

Summaries for Dysembryoplastic Neuroepithelial Tumor

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MalaCards based summary: Dysembryoplastic Neuroepithelial Tumor, also known as dysembryoplastic neuroepithelial neoplasm, is related to ganglioglioma and subependymal giant cell astrocytoma, and has symptoms including seizures An important gene associated with Dysembryoplastic Neuroepithelial Tumor is SYP (Synaptophysin), and among its related pathways are Nuclear signaling by ERBB4 and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include temporal lobe, brain and cerebellum.

Related Diseases for Dysembryoplastic Neuroepithelial Tumor

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Diseases related to Dysembryoplastic Neuroepithelial Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 128)
idRelated DiseaseScoreTop Affiliating Genes
1ganglioglioma31.0GFAP, IDH1
2subependymal giant cell astrocytoma30.0GFAP, S100B
3rosette-forming glioneuronal tumor of fourth ventricule11.3
4epilepsy10.6
52q33.1 microdeletion syndrome10.5MAP2, SYP
6oligodendroglioma10.5
7sm-ahnmd10.5NES, SYP
8astrocytoma10.4
9grubben de cock borghgraef syndrome10.4GFAP, SYP
10bladder flat intraepithelial lesion10.4GFAP, SYP
11lice infestation10.4GFAP, SYP
12cauda equina neoplasm10.4GFAP, SYP
13glomus tumor10.4GFAP, SYP
14vulvar benign neoplasm10.4GFAP, SYP
15hypersensitivity reaction type ii disease10.4GFAP, SYP
16brainstem intraparenchymal clear cell meningioma10.4GFAP, SYP
17benign breast phyllodes tumor10.4IDH1, SYP
18empty sella syndrome10.4GFAP, NES
19atypical choroid plexus papilloma10.4GFAP, SYP
20anaplastic oligodendroglioma10.4GFAP, NES
21pilomyxoid astrocytoma10.4GFAP, SYP
22cauda equina intradural extramedullary astrocytoma10.4GFAP, SYP
23choroid disease10.4GFAP, SYP
24vitamin metabolic disorder10.4GFAP, SYP
25pineoblastoma10.4GFAP, SYP
26cervical alveolar soft part sarcoma10.4GFAP, NES
27plexopathy10.4GFAP, SYP
28malignant granular cell esophageal tumor10.4GFAP, SYP
29malignant pineal area germ cell neoplasm10.4GFAP, SYP
30diencephalic astrocytomas10.4GFAP, SYP
31pulmonary plasma cell granuloma10.3GFAP, SYP
32o'sullivan-mcleod syndrome10.3MAP2, NES
33amyotrophic lateral sclerosis type 1410.3MAP2, SYP
34peritoneal benign neoplasm10.3GFAP, SYP
35mesenchymoma10.3GFAP, SYP
36papillary thymic adenocarcinoma10.3IDH1, SYP
37pilocytic astrocytoma10.3
38central nervous system sarcoma10.3GFAP, SYP
39cervical benign neoplasm10.3GFAP, NES
40adult central nervous system primitive neuroectodermal neoplasm10.3GFAP, SYP
41pediatric ependymoma10.3GFAP, SYP
42intrahepatic bile duct cystadenoma10.2GFAP, IDH1
43temporal lobe epilepsy10.2
44pleomorphic xanthoastrocytoma10.2
45neuronitis10.2
46glioma10.2
47cervical adenoid cystic carcinoma10.2GFAP, IDH1
48early myoclonic encephalopathy10.2GFAP, IDH1
49central nervous system vasculitis10.2GFAP, SYP
50kidney osteogenic sarcoma10.2GRIN1, MAP2

Graphical network of the top 20 diseases related to Dysembryoplastic Neuroepithelial Tumor:



Diseases related to dysembryoplastic neuroepithelial tumor

Symptoms for Dysembryoplastic Neuroepithelial Tumor

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UMLS symptoms related to Dysembryoplastic Neuroepithelial Tumor:


seizures

Drugs & Therapeutics for Dysembryoplastic Neuroepithelial Tumor

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Molecular-Guided Therapy for Childhood CancerRecruitingNCT02162732

Search NIH Clinical Center for Dysembryoplastic Neuroepithelial Tumor

Genetic Tests for Dysembryoplastic Neuroepithelial Tumor

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Anatomical Context for Dysembryoplastic Neuroepithelial Tumor

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MalaCards organs/tissues related to Dysembryoplastic Neuroepithelial Tumor:

34
Temporal lobe, Brain, Cerebellum, Caudate nucleus, Thalamus, Parietal lobe, Cortex

Animal Models for Dysembryoplastic Neuroepithelial Tumor or affiliated genes

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Publications for Dysembryoplastic Neuroepithelial Tumor

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Articles related to Dysembryoplastic Neuroepithelial Tumor:

(show top 50)    (show all 124)
idTitleAuthorsYear
1
Remitted epilepsy with dysembryoplastic neuroepithelial tumor involving the thalamus. (27163491)
2016
2
Resection of a dysembryoplastic neuroepithelial tumor in the precentral gyrus. (26253415)
2015
3
BRAF V600E mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas. (25346165)
2015
4
Mixed glioneuronal tumor: a dysembryoplastic neuroepithelial tumor with rosette-forming glioneuronal tumor component. (23163721)
2013
5
Focal epilepsy associated with dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus. (22809555)
2012
6
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma. (22990729)
2012
7
Dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: review of 2 cases with chromosome 1p/19q and IDH1 analysis. (22192702)
2012
8
Lhermitte-Duclos disease associated with dysembryoplastic neuroepithelial tumor differentiation with characteristic magnetic resonance appearance of "tiger striping". (21704939)
2011
9
A patient with a dysembryoplastic neuroepithelial tumor who underwent epilepsy surgery after initial seizure. (22777137)
2011
10
Dysembryoplastic neuroepithelial tumor and calcifying pseudoneoplasms of the neuraxis: a collision of two seizure-associated lesions. (21726506)
2011
11
Diffuse hemispheric dysembryoplastic neuroepithelial tumor: a new radiological variant associated with early-onset severe epilepsy. (21456916)
2011
12
Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients. (20043747)
2010
13
Progressive biological behavior of a dysembryoplastic neuroepithelial tumor. (21196795)
2010
14
F-18 FDG-PET imaging of dysembryoplastic neuroepithelial tumor-like astrocytoma. (19893407)
2009
15
Clinicopathologic features of recurrent dysembryoplastic neuroepithelial tumor and rare malignant transformation: a report of 5 cases and review of the literature. (19267228)
2009
16
Intraventricular dysembryoplastic neuroepithelial tumor-like neoplasm with disseminated spinal tumor. (19263357)
2009
17
Dysembryoplastic neuroepithelial tumor: a clinicopathological study of 32 cases. (19165515)
2009
18
Dysembryoplastic neuroepithelial tumor located in pericallosal and intraventricular area in a child. Case report. (19485727)
2009
19
Different pattern of expression of nestin in the non-specific form of dysembryoplastic neuroepithelial tumors compared to the simple and complex forms. (18998057)
2009
20
Surgery for epilepsy in children with dysembryoplastic neuroepithelial tumor: clinical spectrum, seizure outcome, neuroradiology, and pathology. (19066912)
2009
21
Recurrence of dysembryoplastic neuroepithelial tumor following resection. (18552517)
2008
22
Dysembryoplastic neuroepithelial tumor of the brainstem. (24256828)
2008
23
The development of ring-shaped contrast enhancement in a case of cerebellar dysembryoplastic neuroepithelial tumor: case report. (18812941)
2008
24
MR and CT Evaluation of Dysembryoplastic Neuroepithelial Tumor. A Case Report. (24257009)
2008
25
Intraventricular dysembryoplastic neuroepithelial tumor: case report. (18162864)
2007
26
Gamma knife radiosurgery for epilepsy related to dysembryoplastic neuroepithelial tumor. (17063046)
2006
27
Development of contrast enhancement after long-term observation of a dysembryoplastic neuroepithelial tumor. (16314940)
2006
28
Clinical features and epileptogenesis of dysembryoplastic neuroepithelial tumor. (16944177)
2006
29
Frequent association of cortical dysplasia in dysembryoplastic neuroepithelial tumor treated by epilepsy surgery. (16253690)
2005
30
Perfusion MR imaging and proton MR spectroscopy in a case of dysembryoplastic neuroepithelial tumor. (16098271)
2005
31
Recurrent intractable seizures in children with cortical dysplasia adjacent to dysembryoplastic neuroepithelial tumor. (15921242)
2005
32
Usefulness of [11C]methionine PET in the diagnosis of dysembryoplastic neuroepithelial tumor with temporal lobe epilepsy. (14692906)
2004
33
Dysembryoplastic neuroepithelial tumor in the left lateral ventricle. (14628248)
2003
34
Dysembryoplastic neuroepithelial tumor. Features distinguishing it from oligodendroglioma on cytologic squash preparations. (12920757)
2003
35
Dysembryoplastic neuroepithelial tumor or dysembryoplastic cortical neurocytoma? (12777091)
2003
36
Malignant transformation of a dysembryoplastic neuroepithelial tumor after radiation and chemotherapy. (12913847)
2003
37
MAP2 and nestin co-expression in dysembryoplastic neuroepithelial tumors. (12670051)
2003
38
A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor? (11979088)
2002
39
Various findings in surgically treated epilepsy patients with dysembryoplastic neuroepithelial tumors in comparison with those of patients with other low-grade brain tumors and other neuronal migration disorders. (12423388)
2002
40
Genetic differences between neurocytoma and dysembryoplastic neuroepithelial tumor and oligodendroglial tumors. (12507133)
2002
41
Dysembryoplastic neuroepithelial tumor of the midbrain tectum: a case report. (12622140)
2002
42
Dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: a lesion often misdiagnosed as glioma: report of 10 cases. (11257624)
2001
43
Dysembryoplastic neuroepithelial tumor: radiological findings (including PET, SPECT, and MRS) and surgical strategy. (10982159)
2000
44
A case of an unclassified tumor closely resembling dysembryoplastic neuroepithelial tumor with rapid growth. (10982009)
2000
45
Infratentorial dysembryoplastic neuroepithelial tumor (DNT) associated with Arnold-Chiari malformation. (9832257)
1998
46
Dysembryoplastic neuroepithelial tumor. Case report]. (9629369)
1997
47
A case of dysembryoplastic neuroepithelial tumor of the parietal lobe with characteristic magnetic resonance imaging. (8677797)
1996
48
Dysembryoplastic neuroepithelial tumor: a clinicopathologic and immunohistochemical study of 11 tumors including MIB1 immunoreactivity. (8998857)
1996
49
Radiologic appearance of the dysembryoplastic neuroepithelial tumor. (7568829)
1995
50
Dysembryoplastic neuroepithelial tumor: morphological, immunocytochemical, and deoxyribonucleic acid analyses in a pediatric series. (7753346)
1995

Variations for Dysembryoplastic Neuroepithelial Tumor

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Expression for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Search GEO for disease gene expression data for Dysembryoplastic Neuroepithelial Tumor.

Pathways for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Pathways related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5GFAP, S100B
28.0GFAP, MAP2, NES, S100B, SYP
37.7GFAP, GRIN1, MAP2, S100B, SYP

GO Terms for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Cellular components related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.7GFAP, NES
2excitatory synapseGO:00600769.4GRIN1, SYP
3terminal boutonGO:00431959.3GRIN1, SYP
4neuron projectionGO:00430058.4GRIN1, MAP2, SYP

Biological processes related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1long-term synaptic potentiationGO:00602919.6GFAP, S100B
2memoryGO:00076139.1GRIN1, S100B
3learning or memoryGO:00076119.1GRIN1, S100B
4regulation of long-term neuronal synaptic plasticityGO:00481699.0GRIN1, SYP
5regulation of neuronal synaptic plasticityGO:00481688.9GRIN1, S100B, SYP

Molecular functions related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.1GFAP, MAP2, NES
2receptor bindingGO:00051028.7GRIN1, IDH1, S100B

Sources for Dysembryoplastic Neuroepithelial Tumor

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
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26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
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44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet