MCID: DYS006
MIFTS: 34

Dysembryoplastic Neuroepithelial Tumor malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Dysembryoplastic Neuroepithelial Tumor

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Aliases & Descriptions for Dysembryoplastic Neuroepithelial Tumor:

Name: Dysembryoplastic Neuroepithelial Tumor 10 45 12 51 65
Dysembryoplastic Neuroepithelial Neoplasm 10
 
Dnet 51

Characteristics:

Orphanet epidemiological data:

51
dysembryoplastic neuroepithelial tumor:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Disease Ontology10 DOID:2679
NCIt42 C9505
SNOMED-CT59 128788005
Orphanet51 251946
UMLS via Orphanet66 C1266177
UMLS65 C1266177

Summaries for Dysembryoplastic Neuroepithelial Tumor

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MalaCards based summary: Dysembryoplastic Neuroepithelial Tumor, also known as dysembryoplastic neuroepithelial neoplasm, is related to pilocytic astrocytoma and subependymal giant cell astrocytoma, and has symptoms including seizures An important gene associated with Dysembryoplastic Neuroepithelial Tumor is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic), and among its related pathways are Central carbon metabolism in cancer and Signal transduction_Erk Interactions- Inhibition of Erk. Affiliated tissues include lung, breast and bone.

Related Diseases for Dysembryoplastic Neuroepithelial Tumor

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Diseases related to Dysembryoplastic Neuroepithelial Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1pilocytic astrocytoma30.9IDH1, KIAA1549
2subependymal giant cell astrocytoma30.5IDH1, KIAA1549
3pleomorphic xanthoastrocytoma30.1IDH1, KIAA1549, SYP
4rosette-forming glioneuronal tumor of fourth ventricule11.3
5oligodendroglioma10.5
6astrocytoma10.4
7ganglioglioma10.4
8familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.3IDH1, SYP
9diencephalic astrocytomas10.3IDH1, KIAA1549
10sympathetic neurilemmoma10.3IDH1, SYP
11hypothalamic neoplasm10.2RBFOX3, SYP
12childhood infratentorial neoplasm10.2KIAA1549, SYP
13mixed ductal-endocrine carcinoma10.2RBFOX3, SYP
14adult choroid plexus cancer10.2RBFOX3, SYP
15pilomyxoid astrocytoma10.2RBFOX3, SYP
16temporal lobe epilepsy10.2
17neuronitis10.2
18glioma10.2
19lung benign neoplasm10.2RBFOX3, SYP
20colon small cell carcinoma10.2IDH1, KIAA1549
21cerebellar astrocytoma10.2RBFOX3, SYP
22melanotic neuroectodermal tumor10.2RBFOX3, SYP
23gastric papillary adenocarcinoma10.2IDH1, SYP
24papillary ependymoma10.2RBFOX3, SYP
25breast adenomyoepithelial adenosis10.1IDH1, SYP
26clear cell ependymoma10.1RBFOX3, SYP
27adult astrocytic tumour10.1IDH1, SYP
28lipoma of the rectum10.1RBFOX3, SYP
29brain stem ependymoma10.1RBFOX3, SYP
30childhood cerebral astrocytoma10.1IDH1, SYP
31atypical teratoid rhabdoid tumor10.1
32focal epilepsy10.1
33glioblastoma multiforme10.1
34chiari malformation10.1
35glioblastoma10.1
36hemimegalencephaly10.1
37neuronal migration disorders10.1
38angiocentric glioma10.1
39brachyolmia10.0IDH1, SYP
40gliosarcoma9.9IDH1, KIAA1549
41childhood oligodendroglioma9.9IDH1, SYP
42cauda equina intradural extramedullary astrocytoma9.8KIAA1549, RBFOX3, SYP
43enthesopathy9.7AKT3, MYT1
44cardiovascular organ benign neoplasm9.7KIAA1549, MYT1, SYP
45spinal cord oligodendroglioma9.4IDH1, KIAA1549, RBFOX3, SYP
46paranasal sinus disease9.3AKT3, SYP
47liver angiosarcoma7.6AKT3, GRIN1, IDH1, KIAA1549, MYT1, RBFOX3

Graphical network of the top 20 diseases related to Dysembryoplastic Neuroepithelial Tumor:



Diseases related to dysembryoplastic neuroepithelial tumor

Symptoms for Dysembryoplastic Neuroepithelial Tumor

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UMLS symptoms related to Dysembryoplastic Neuroepithelial Tumor:


seizures

Drugs & Therapeutics for Dysembryoplastic Neuroepithelial Tumor

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Molecular-Guided Therapy for Childhood CancerRecruitingNCT02162732

Search NIH Clinical Center for Dysembryoplastic Neuroepithelial Tumor

Genetic Tests for Dysembryoplastic Neuroepithelial Tumor

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Anatomical Context for Dysembryoplastic Neuroepithelial Tumor

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MalaCards organs/tissues related to Dysembryoplastic Neuroepithelial Tumor:

33
Lung, Breast, Bone, Temporal lobe, Brain, Prostate, Liver

Animal Models for Dysembryoplastic Neuroepithelial Tumor or affiliated genes

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MGI Mouse Phenotypes related to Dysembryoplastic Neuroepithelial Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Dysembryoplastic Neuroepithelial Tumor

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Articles related to Dysembryoplastic Neuroepithelial Tumor:

(show top 50)    (show all 124)
idTitleAuthorsYear
1
Atypical Teratoid Rhabdoid Tumor Diagnosis after Partial Resection of Dysembryoplastic Neuroepithelial Tumor: Case Report and Review of the Literature. (26978682)
2016
2
Remitted epilepsy with dysembryoplastic neuroepithelial tumor involving the thalamus. (27163491)
2016
3
Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor. (27181792)
2016
4
Long-term drug-resistant temporal lobe epilepsy associated with a mixed ganglioglioma and dysembryoplastic neuroepithelial tumor in an elderly patient. (27127715)
2016
5
Resection of a dysembryoplastic neuroepithelial tumor in the precentral gyrus. (26253415)
2015
6
Dysembryoplastic neuroepithelial tumor, a pure glial tumor? Immunohistochemical and morphometric studies. (23530928)
2013
7
Recurrence and histological evolution of dysembryoplastic neuroepithelial tumor: A case report and review of the literature. (24137435)
2013
8
Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression. (23442159)
2013
9
Electrocorticographic-histopathologic correlations implying epileptogenicity of dysembryoplastic neuroepithelial tumor. (24077279)
2013
10
Dysembryoplastic Neuroepithelial Tumor: A Clinical, Neuroradiological, and Pathological Study of 15 Cases. (23752069)
2013
11
Composite ganglioglioma/dysembryoplastic neuroepithelial tumor: a clinicopathologic study of 8 cases. (22221701)
2012
12
Focal epilepsy associated with dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus. (22809555)
2012
13
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma. (22990729)
2012
14
Intraventricular dysembryoplastic neuroepithelial tumor in a pediatric patient: is it the most common extracortical location for DNT? (20959995)
2011
15
Lhermitte-Duclos disease associated with dysembryoplastic neuroepithelial tumor differentiation with characteristic magnetic resonance appearance of "tiger striping". (21704939)
2011
16
F-18 FDG-PET imaging of dysembryoplastic neuroepithelial tumor-like astrocytoma. (19893407)
2009
17
Clinicopathologic features of recurrent dysembryoplastic neuroepithelial tumor and rare malignant transformation: a report of 5 cases and review of the literature. (19267228)
2009
18
Intraventricular dysembryoplastic neuroepithelial tumor-like neoplasm with disseminated spinal tumor. (19263357)
2009
19
Dysembryoplastic neuroepithelial tumor: a clinicopathological study of 32 cases. (19165515)
2009
20
Editorial. Dysembryoplastic neuroepithelial tumor. (19485726)
2009
21
Familial occurrence of dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: case report. (18797318)
2008
22
Electroencephalography-guided resection of dysembryoplastic neuroepithelial tumor: case report. (18654053)
2008
23
Gamma knife radiosurgery for epilepsy related to dysembryoplastic neuroepithelial tumor. (17063046)
2006
24
Endoscopic resection of an intraventricular dysembryoplastic neuroepithelial tumor of the septum pellucidum. (16465080)
2006
25
Frequent association of cortical dysplasia in dysembryoplastic neuroepithelial tumor treated by epilepsy surgery. (16253690)
2005
26
A nonspecific form of dysembryoplastic neuroepithelial tumor presenting with intractable epilepsy. (18095102)
2005
27
Perfusion MR imaging and proton MR spectroscopy in a case of dysembryoplastic neuroepithelial tumor. (16098271)
2005
28
Recurrent intractable seizures in children with cortical dysplasia adjacent to dysembryoplastic neuroepithelial tumor. (15921242)
2005
29
Usefulness of [11C]methionine PET in the diagnosis of dysembryoplastic neuroepithelial tumor with temporal lobe epilepsy. (14692906)
2004
30
Dysembryoplastic neuroepithelial tumor in the left lateral ventricle. (14628248)
2003
31
Dysembryoplastic neuroepithelial tumor. Features distinguishing it from oligodendroglioma on cytologic squash preparations. (12920757)
2003
32
Dysembryoplastic neuroepithelial tumor or dysembryoplastic cortical neurocytoma? (12777091)
2003
33
Malignant transformation of a dysembryoplastic neuroepithelial tumor after radiation and chemotherapy. (12913847)
2003
34
A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor? (11979088)
2002
35
Various findings in surgically treated epilepsy patients with dysembryoplastic neuroepithelial tumors in comparison with those of patients with other low-grade brain tumors and other neuronal migration disorders. (12423388)
2002
36
Dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: a lesion often misdiagnosed as glioma: report of 10 cases. (11257624)
2001
37
Bcl-2, bcl-x, and bax expression in dysembryoplastic neuroepithelial tumors. (10749285)
2000
38
Dysembryoplastic neuroepithelial tumor of the cerebellum and brainstem. Case report. (10969950)
2000
39
Dysembryoplastic neuroepithelial tumor: radiological findings (including PET, SPECT, and MRS) and surgical strategy. (10982159)
2000
40
A case of an unclassified tumor closely resembling dysembryoplastic neuroepithelial tumor with rapid growth. (10982009)
2000
41
Dysembryoplastic neuroepithelial tumor. (10087102)
1999
42
Infratentorial dysembryoplastic neuroepithelial tumor (DNT) associated with Arnold-Chiari malformation. (9832257)
1998
43
Mixed dysembryoplastic neuroepithelial tumor and ganglioglioma. (9650758)
1998
44
Dysembryoplastic neuroepithelial tumor and oligodendroglioma: the diagnostic value of magnetic resonance spectroscopy. Case report and review of the literature. (17168506)
1998
45
Dysembryoplastic neuroepithelial tumor. Case report]. (9629369)
1997
46
Neural antigens in oligodendrogliomas and dysembryoplastic neuroepithelial tumors. (9386775)
1997
47
Mesial temporal dysembryoplastic neuroepithelial tumor mimicking oligodendroglioma: a case report and review of the literature. (9041772)
1996
48
A case of dysembryoplastic neuroepithelial tumor of the parietal lobe with characteristic magnetic resonance imaging. (8677797)
1996
49
How would you treat this patient? Dysembryoplastic neuroepithelial tumor. (8677483)
1996
50
Dysembryoplastic neuroepithelial tumor: report of a case without typical glioneuronal elements. (7754749)
1995

Variations for Dysembryoplastic Neuroepithelial Tumor

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Expression for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Search GEO for disease gene expression data for Dysembryoplastic Neuroepithelial Tumor.

Pathways for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Pathways related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3AKT3, IDH1
29.2AKT3, GRIN1

GO Terms for genes affiliated with Dysembryoplastic Neuroepithelial Tumor

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Cellular components related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1synaptic vesicleGO:00080219.6GRIN1, SYP

Biological processes related to Dysembryoplastic Neuroepithelial Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to organic cyclic compoundGO:00140709.7GRIN1, IDH1

Sources for Dysembryoplastic Neuroepithelial Tumor

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet