MCID: DYS015
MIFTS: 40

Dysentery malady

Summaries for Dysentery

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in severe diarrhea with passage of mucus and blood.

MalaCards: Dysentery, also known as infectious diarrhea, is related to shigellosis and amebiasis. An important gene associated with Dysentery is PEAR1 (platelet endothelial aggregation receptor 1), and among its related pathways is HIF-1 signaling pathway. The drugs ciprofloxacin and scopolamine and the compounds mizoribine and polyvinyl alcohol have been mentioned in the context of this disorder. Related mouse phenotype cellular.

Wikipedia:64 Dysentery (formerly known as Flux or the bloody flux) is an inflammatory disorder of the intestine,... more...

Aliases & Classifications for Dysentery

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 45Novoseek, 57SNOMED-CT, 27ICD9CM, 35MeSH
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Aliases & Descriptions:

dysentery 8 10 61
infectious diarrhea 8 45


Related Diseases for Dysentery

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Dysentery via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 73)
idRelated DiseaseScoreTop Affiliating Genes
1shigellosis30.6QTRT1, CD79A
2amebiasis30.4CD79A, MYO1B
3arthritis29.8PHB2, VIPR1
4cholera10.3
5n syndrome10.3
6typhoid fever10.2
7protozoal dysentery10.2
8campylobacteriosis10.2
9irritable bowel syndrome10.2
10treponema infection10.2
11acute diarrhea10.1
12ulcerative colitis10.1
13paratyphoid fever10.1
14hemolytic-uremic syndrome10.1
15lactose intolerance10.0
16clostridium difficile10.0
17phlebotomus fever10.0CCDC130
18herpes zoster10.0TMPO
19acquired immunodeficiency syndrome10.0WARS
20multiple sclerosis10.0TMPO
21severe acute respiratory syndrome10.0SENP6
22diarrhea10.0CD79A
23polycythemia vera10.0IFNA2
24gastroenteritis10.0CD79A
25pancreatic cancer10.0IGF1
26schistosomiasis10.0CD79A
27pneumonia10.0CD79A
28dermatitis10.0CD79A
29sinusitis10.0CD79A
30cerebral primitive neuroectodermal tumor10.0ENO2
31hypothyroidism10.0TMPO, IGF1
32bronchitis10.0CD79A
33pheochromocytoma10.0ENO2, VIPR1
34wilson disease10.0TF
35protein-losing enteropathy10.0TF
36adenocarcinoma10.0VIPR1, ENO2
37rheumatoid arthritis10.0CD79A, TMPO
38urethritis10.0CD79A, PHB2
39inflammatory bowel disease10.0CD79A
40neuropathy10.0CD79A
41arthropathy10.0TF, PHB2
42membranoproliferative glomerulonephritis10.0CD79A, IFNA2
43leukopenia10.0CD79A, TMPO, IFNA2
44protein-energy malnutrition10.0TF, IGF1
45siderosis10.0TF
46nephrotic syndrome10.0TF, CD79A
47liver cirrhosis10.0TF, IFNA2, VIPR1
48hepatitis10.0IFNA2, VIPR1, TF
49lipoid nephrosis10.0CD79A, TF
50hepatitis c10.0IFNA2, VIPR1, TF

Graphical network of the top 20 diseases related to Dysentery:



Diseases related to dysentery

Clinical Features for Dysentery

Drugs & Therapeutics for Dysentery

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Dysentery

Drug clinical trials:

Search ClinicalTrials for Dysentery

Search NIH Clinical Center for Dysentery

Search CenterWatch for Dysentery

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Dysentery

Anatomical Context for Dysentery

Animal Models for Dysentery or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Dysentery:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.9PELO, TMPO, ENO2, CD79A, QTRT1, IGF1

Publications for Dysentery

Sources:
51PubMed
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Articles related to Dysentery:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
Applied mixed generalized additive model to assess the effect of temperature on the incidence of bacillary dysentery and its forecast. (23637978)
2013
2
Comparison of atypical Brachyspira spp. clinical isolates and classic strains in a mouse model of swine dysentery. (22770518)
2012
3
Solar disinfection of drinking water in the prevention of dysentery in South African children aged under 5 years: the role of participant motivation. (20977257)
2010
4
Dyspnea and dysentery: a case report of pleuropulmonary amebiasis. (20175253)
2010
5
Child dysentery in the Limpopo Valley: a cohort study of water, sanitation and hygiene risk factors. (19240352)
2009
6
Crusaders' dysentery. (18718438)
2008
7
Molecular characterization of HE, M, and E genes of winter dysentery bovine coronavirus circulated in Korea during 2002-2003. (16604443)
2006
8
Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery. (16890598)
2006
9
Investigating bacillary dysentery: the role of laboratory, technique and people. (16600682)
2006
10
Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilli in vivo and in vitro. (15587409)
2004
11
Differences in lymphocyte subpopulations and cell counts before and after experimentally induced swine dysentery. (15017281)
2004
12
Experimental swine dysentery: comparison between infection models. (15017282)
2004
13
Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates. (10805255)
2000
14
Treatment of bacillary dysentery in Vietnamese children: two doses of ofloxacin versus 5-days nalidixic acid. (10975012)
2000
15
Absorption of macronutrients and nitrogen balance in children with dysentery fed an amylase-treated energy-dense porridge. (9475307)
1997
16
Zinc supplementation reduces the incidence of persistent diarrhea and dysentery among low socioeconomic children in India. (8632217)
1996
17
Comparison of ELISA and selective culture in the diagnosis of swine dysentery in Thailand. (8730676)
1996
18
Antigenic and biological comparisons of bovine coronaviruses derived from neonatal calf diarrhea and winter dysentery of adult cattle. (7646362)
1995
19
Antimicrobial susceptibilities of Shigella dysenteriae type 1 isolated in Zimbabwe--implications for the management of dysentery. (7788685)
1995
20
Infection, diarrhea, and dysentery caused by Shigella species and Campylobacter jejuni among Guatemalan rural children. (8177630)
1994
21
Value of microscopy in the diagnosis of dysentery associated with invasive Entamoeba histolytica. (8163695)
1994
22
Immunoepidemiology of intestinal helminthic infections. 3. Mucosal macrophages and cytokine production in the colon of children with Trichuris trichiura dysentery. (7974659)
1994
23
Exacerbated onset of dysentery in swine vaccinated with inactivated adjuvanted Serpulina hyodysenteriae. (8141499)
1994
24
Developmental levels and nutritional status of children with the Trichuris dysentery syndrome. (7505495)
1993
25
Histopathology and immunohistochemistry of the caecum in children with the Trichuris dysentery syndrome. (2013619)
1991
26
A review of evidence implicating bovine coronavirus in the etiology of winter dysentery in cows: an enigma resolved? (2170075)
1990
27
Prevention of diarrhoea and dysentery by hand washing. (2603190)
1989
28
Winter dysentery in adult dairy cattle. (2557701)
1989
29
Coronavirus-associated diarrhea (winter dysentery) in adult cattle. (17423442)
1989
30
The research on the acupuncture treatment of acute bacillary dysentery. (22557609)
1988
31
Dysentery associated with invasive E. coli 028ac in an adult: a case report. (3319510)
1987
32
Outbreak of Shigella sonnei dysentery on a long stay psychogeriatric ward. (2888815)
1987
33
Treatment of bacillary dysentery: a comparison between enoxacin and nalidixic acid. (3301783)
1987
34
Genetic determinants of virulence in Shigella and dysenteric strains of Escherichia coli: their involvement in the pathogenesis of dysentery. (2414072)
1985
35
Bacillary dysentery. (6386299)
1984
36
Swine dysentery: the influence of dietary selenium on clinical and pathological effects of Treponema hyodysenteriae infection. (6464915)
1984
37
Aspects of the dysentery evolution in the territory surveilled by the Sanitary-Antiepidemic Center of B Municipality--Laboratory No 2 (Administrative District 2 and 3) after the introduction of the dysentery vaccination. (6400309)
1984
38
Epidemic dysentery caused by the Shiga bacillus in a southern Indian village. (6389664)
1984
39
Epidemic of dysentery in West Bengal: clinicians' enigma. (6150220)
1984
40
Outbreak of Shigella sonnei dysentery on a geriatric assessment ward. (6205062)
1984
41
Further contributions towards the ethnobotany of madhya pradesh 2: plants used against diarrhoea and dysentery. (22556976)
1983
42
Outbreak of Shigella dysentery in Eastern Zaire, 1980-1982. (6344814)
1983
43
Eradication of swine dysentery from closed pig herds. (7292933)
1981
44
Association of cockroaches with an outbreak of dysentery. (7029807)
1981
45
Effects of aflatoxin consumption on the clinical course of swine dysentery. (7271036)
1981
46
Shigella toxin(s): description and role in diarrhea and dysentery. (7048347)
1981
47
Amoebic dysentery complicating an abdominal aortic aneurysmectomy. (7210134)
1980
48
An evaluation of the API ZYM system as a means of classifying spirochaetes associated with swine dysentery. (473537)
1979
49
Sensitivity in vitro to dimetridazole of treponemes associated with swine dysentery. (433115)
1979
50
An interesting case of chronic amoebic dysentery with abdominal tuberculosis. (14903941)
1952

Genetic Variations for Dysentery

Expression for genes affiliated with Dysentery

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dysentery

Search GEO for disease gene expression data for Dysentery.

Pathways for genes affiliated with Dysentery

Sources:
30KEGG
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Pathways related to Dysentery according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7ENO2, IGF1, TF

Compounds for genes affiliated with Dysentery

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 29IUPHAR, 24HMDB
See all sources

Compounds related to Dysentery according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1mizoribine4510.4IFNA2, CD79A
2polyvinyl alcohol4510.4IFNA2, IGF1
3nandrolone decanoate45 1111.3IGF1, TF
4gamma globulin4510.2IFNA2, CD79A
5starch4510.2IGF1, TF, IFNA2
6betacarotene4510.1IFNA2, TF, CD79A
7vitamin b124510.1CD79A, IGF1, TF
8megestrol acetate4510.0IGF1, IFNA2
9polyethylene glycol4510.0CD79A, TF, IFNA2
10ribavirin45 50 1112.0VIPR1, IFNA2, TF
11octreotide45 60 29 1113.0IFNA2, IGF1, ENO2
12thyroxine45 2411.0IFNA2, TF, IGF1, CD79A
13alpha tocopherol459.9IFNA2, TF, IGF1
14prednisolone45 29 1111.8CD79A, TF, IFNA2
15acth459.8TMPO, ENO2, IGF1, IFNA2
16galactose459.8CD79A, GALM, IFNA2
17indomethacin45 60 29 1112.7IFNA2, CD79A, ENO2, TMPO
18tuberculin459.6CD79A, ENO2
19anticodon459.6WARS, QTRT1
20dopamine45 29 11 2412.6ENO2, CD79A, IGF1, TF, IFNA2
21estrogen459.0ENO2, CD79A, IGF1, PHB2, TF, IFNA2
22alanine458.9ENO2, CD79A, TF, WARS, IFNA2, VIPR1
23glucose458.4VIPR1, IFNA2, GALM, UGGT1, IGF1, ENO2

GO Terms for genes affiliated with Dysentery

Products for genes affiliated with Dysentery

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Sources for Dysentery

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet