MCID: DYS015
MIFTS: 45

Dysentery malady

Summaries for Dysentery

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in severe diarrhea with passage of mucus and blood.

MalaCards: Dysentery, also known as infectious diarrhea, is related to diarrhea and shigellosis. An important gene associated with Dysentery is PEAR1 (platelet endothelial aggregation receptor 1), and among its related pathways is HIF-1 signaling pathway. The drugs ciprofloxacin and scopolamine and the compounds mizoribine and polyvinyl alcohol have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and liver, and related mouse phenotype cellular.

Wikipedia:63 Dysentery (formerly known as Flux or the bloody flux) is an inflammatory disorder of the intestine,... more...

Aliases & Classifications for Dysentery

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH
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Aliases & Descriptions:

dysentery 8 10 60
infectious diarrhea 8 44


Related Diseases for Dysentery

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17GeneCards, 18GeneDecks
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Diseases related to Dysentery via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 75)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea30.8CD79A
2shigellosis30.5CD79A, QTRT1
3amebiasis30.4MYO1B, CD79A
4gastroenteritis30.2CD79A
5pneumonia30.2CD79A
6inflammatory bowel disease30.0CD79A
7arthritis29.8VIPR1, PHB2
8dermatitis29.8CD79A
9neuropathy29.8CD79A
10cholera10.2
11typhoid fever10.2
12protozoal dysentery10.1
13campylobacteriosis10.1
14irritable bowel syndrome10.1
15acute diarrhea10.0
16ulcerative colitis10.0
17paratyphoid fever10.0
18hemolytic-uremic syndrome10.0
19phlebotomus fever10.0CCDC130
20herpes zoster10.0TMPO
21acquired immunodeficiency syndrome10.0WARS
22multiple sclerosis10.0TMPO
23severe acute respiratory syndrome10.0SENP6
24polycythemia vera10.0IFNA2
25pancreatic cancer10.0IGF1
26schistosomiasis10.0CD79A
27sinusitis10.0CD79A
28lactose intolerance10.0
29cerebral primitive neuroectodermal tumor10.0ENO2
30hypothyroidism10.0TMPO, IGF1
31bronchitis10.0CD79A
32pheochromocytoma10.0VIPR1, ENO2
33wilson disease10.0TF
34protein-losing enteropathy10.0TF
35adenocarcinoma10.0ENO2, VIPR1
36rheumatoid arthritis10.0TMPO, CD79A
37urethritis10.0CD79A, PHB2
38arthropathy10.0TF, PHB2
39membranoproliferative glomerulonephritis10.0CD79A, IFNA2
40leukopenia10.0TMPO, CD79A, IFNA2
41protein-energy malnutrition10.0IGF1, TF
42siderosis10.0TF
43nephrotic syndrome10.0TF, CD79A
44liver cirrhosis10.0TF, IFNA2, VIPR1
45hepatitis10.0TF, IFNA2, VIPR1
46lipoid nephrosis10.0CD79A, TF
47hepatitis c10.0TF, IFNA2, VIPR1
48galactosemia10.0CD79A, IGF1, TF
49primary hyperoxaluria10.0TF, IGF1, CD79A
50diabetes mellitus10.0TF, IGF1, CD79A

Graphical network of the top 20 diseases related to Dysentery:



Diseases related to dysentery

Clinical Features for Dysentery

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Drugs & Therapeutics for Dysentery

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Dysentery

Drug clinical trials:

Search ClinicalTrials for Dysentery

Search NIH Clinical Center for Dysentery

Search CenterWatch for Dysentery

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Dysentery

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Anatomical Context for Dysentery

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32MalaCards
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MalaCards organs/tissues related to Dysentery:

32
Colon, Testes, Liver, Bone marrow, Bone, Small intestine, Breast

Animal Models for Dysentery or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Dysentery:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.9PELO, TMPO, ENO2, CD79A, QTRT1, IGF1

Publications for Dysentery

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50PubMed
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Articles related to Dysentery:

(show top 50)    (show all 499)
idTitleAuthorsYear
1
Applied mixed generalized additive model to assess the effect of temperature on the incidence of bacillary dysentery and its forecast. (23637978)
2013
2
Identifying high-risk areas of bacillary dysentery and associated meteorological factors in Wuhan, China. (24257434)
2013
3
Amoebic dysentery. (21477391)
2011
4
Dyspnea and dysentery: a case report of pleuropulmonary amebiasis. (20175253)
2010
5
Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery. (16890598)
2006
6
Now the second wave: that includes cholera, typhoid fever, dysentery, and other diseases. (15696709)
2005
7
Experimental swine dysentery: comparison between infection models. (15017282)
2004
8
Bilateral pneumonia associated with Shigella sonnei dysentery. (14650419)
2003
9
Field study of bovine coronavirus vaccine enriched with hemagglutinating antigen for winter dysentery in dairy cows. (12418784)
2002
10
Trichuris Dysentery Syndrome: evidence that it may be underdiagnosed in Kelantan. (11503297)
2001
11
Fifty years of dysentery research at the PAccs University. (11791353)
2001
12
Experimental reproduction of winter dysentery in lactating cows using BCV -- comparison with BCV infection in milk-fed calves. (11376958)
2001
13
Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates. (10805255)
2000
14
Evaluation of cow-level risk factors for the development of winter dysentery in dairy cattle. (9706202)
1998
15
Infection and cross-protection studies of winter dysentery and calf diarrhea bovine coronavirus strains in colostrum-deprived and gnotobiotic calves. (8720237)
1996
16
Guidelines for the diagnosis and treatment of dysentery. (8713252)
1995
17
Antimicrobial susceptibilities of Shigella dysenteriae type 1 isolated in Zimbabwe--implications for the management of dysentery. (7788685)
1995
18
Decreased food intake in children with severe dysentery due to Shigella dysenteriae 1 infection. (1425537)
1992
19
Virulent Serpulina hyodysenteriae from a pig in a herd free of clinical swine dysentery. (1441137)
1992
20
Epidemiologic aspects of shigellosis and other causes of dysentery in Thailand. (2047642)
1991
21
Histopathology and immunohistochemistry of the caecum in children with the Trichuris dysentery syndrome. (2013619)
1991
22
Dysentery and Streptococcus pyogenes. (2644361)
1989
23
Indicators of spontaneous and stimulated nitroblue tetrazole test of polymorphous-nuclear leucocytes in acute dysentery patients. (2681402)
1989
24
Coronavirus-associated diarrhea (winter dysentery) in adult cattle. (17423442)
1989
25
Characterization of the agent of swine dysentery based on deoxyribonucleic acid homology. (3394447)
1988
26
Studies on the efficacy of Getroxel against Treponema hyodysenteriae and its role in the control of swine dysentery. (3447462)
1987
27
Acute balantidial dysentery associated with cholera: a case report. (3505854)
1987
28
A double blind trial between metronidazole and secnidazole in acute amebic dysentery in children (preliminary report). (3517763)
1986
29
Comparison of norfloxacin and nalidixic acid for treatment of dysentery caused by Shigella dysenteriae type 1 in adults. (3524434)
1986
30
Dysentery caused by Escherichia coli (S102-9) in calves: natural and experimental disease. (2984830)
1985
31
An epidemic of bacillary dysentery at Raipur. (3891837)
1985
32
Aspects of the dysentery evolution in the territory surveilled by the Sanitary-Antiepidemic Center of B Municipality--Laboratory No 2 (Administrative District 2 and 3) after the introduction of the dysentery vaccination. (6400309)
1984
33
Improvement of production and control methods of live dysentery vaccine Vadizen (Shigella flexneri 2a T32-Istrati). (6400311)
1984
34
Epidemic dysentery caused by the Shiga bacillus in a southern Indian village. (6389664)
1984
35
Prophylaxis of bacillary dysentery by liver vaccine Vadizen (Sh. flexneri T32-Istrati) in children collectivities in IS County. (6400307)
1984
36
Outbreak of Shigella dysentery in Eastern Zaire, 1980-1982. (6344814)
1983
37
Swine dysentery: to isolate or to fluoresce? (6340330)
1983
38
Clinical trial of ampicillin v. trimethoprim-sulphamethoxazole in the treatment of Shigella dysentery. (6757458)
1982
39
Dysentery form gastroenteritis in infancy. (6275330)
1981
40
Comparison of lincomycin and carbadox for treatment and control of swine dysentery. (7254186)
1981
41
Shedding of Treponema hyodysenteriae, transmission of disease, and agglutinin response to pigs convalescent from swine dysentery. (7271009)
1981
42
Effects of aflatoxin consumption on the clinical course of swine dysentery. (7271036)
1981
43
Swine dysentery: a scanning electron microscopic investigation. (7304363)
1981
44
Amoebic dysentery complicating an abdominal aortic aneurysmectomy. (7210134)
1980
45
Bacillary dysentery due to multidrug resistant Sh. dysenteriae type 1. (6991403)
1980
46
An antibody assay in Shiga dysentery by microtiter passive haemagglutination using human erythrocytes and chromium chloride as a coupling reagent. (7380483)
1980
47
Dysentery dialog. (503043)
1979
48
Swine dysentery. (492138)
1979
49
Sensitivity in vitro to dimetridazole of treponemes associated with swine dysentery. (433115)
1979
50
Influence of diet on experimental swine dysentery. 2. Effects of a vitamin E and selenium deficient diet supplemented with 3% cod liver oil, vitamin E or selenium. (655023)
1978

Genetic Variations for Dysentery

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Expression for genes affiliated with Dysentery

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dysentery

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Pathways for genes affiliated with Dysentery

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29KEGG
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Pathways related to Dysentery according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7ENO2, IGF1, TF

Compounds for genes affiliated with Dysentery

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44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 28IUPHAR, 24HMDB
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Compounds related to Dysentery according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1mizoribine4410.4IFNA2, CD79A
2polyvinyl alcohol4410.4IFNA2, IGF1
3nandrolone decanoate44 1111.3IGF1, TF
4gamma globulin4410.2IFNA2, CD79A
5starch4410.2IGF1, TF, IFNA2
6betacarotene4410.1IFNA2, TF, CD79A
7vitamin b124410.1CD79A, IGF1, TF
8megestrol acetate4410.0IGF1, IFNA2
9polyethylene glycol4410.0CD79A, TF, IFNA2
10ribavirin44 49 1112.0VIPR1, IFNA2, TF
11octreotide44 59 28 1113.0IFNA2, IGF1, ENO2
12thyroxine44 2411.0IFNA2, TF, IGF1, CD79A
13alpha tocopherol449.9IFNA2, TF, IGF1
14prednisolone44 28 1111.8CD79A, TF, IFNA2
15acth449.8TMPO, ENO2, IGF1, IFNA2
16galactose449.8CD79A, GALM, IFNA2
17indomethacin44 59 28 1112.7IFNA2, CD79A, ENO2, TMPO
18tuberculin449.6CD79A, ENO2
19anticodon449.6WARS, QTRT1
20dopamine44 28 11 2412.6ENO2, CD79A, IGF1, TF, IFNA2
21estrogen449.0ENO2, CD79A, IGF1, PHB2, TF, IFNA2
22alanine448.9ENO2, CD79A, TF, WARS, IFNA2, VIPR1
23glucose448.4VIPR1, IFNA2, GALM, UGGT1, IGF1, ENO2

GO Terms for genes affiliated with Dysentery

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Products for genes affiliated with Dysentery

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Sources for Dysentery

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet