MCID: DYS015
MIFTS: 45

Dysentery malady

Summaries for Dysentery

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in severe diarrhea with passage of mucus and blood.

MalaCards: Dysentery, also known as infectious diarrhea, is related to diarrhea and shigellosis. An important gene associated with Dysentery is PEAR1 (platelet endothelial aggregation receptor 1), and among its related pathways is HIF-1 signaling pathway. The drugs ciprofloxacin and scopolamine and the compounds mizoribine and polyvinyl alcohol have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and liver, and related mouse phenotype cellular.

Wikipedia:63 Dysentery (formerly known as Flux or the bloody flux) is an inflammatory disorder of the intestine,... more...

Aliases & Classifications for Dysentery

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8Disease Ontology, 10DISEASES, 60UMLS, 44Novoseek, 56SNOMED-CT, 27ICD9CM, 34MeSH
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Aliases & Descriptions:

dysentery 8 10 60
infectious diarrhea 8 44


Related Diseases for Dysentery

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17GeneCards, 18GeneDecks
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Diseases related to Dysentery via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 75)
idRelated DiseaseScoreTop Affiliating Genes
1diarrhea30.8CD79A
2shigellosis30.5CD79A, QTRT1
3amebiasis30.4MYO1B, CD79A
4gastroenteritis30.2CD79A
5pneumonia30.2CD79A
6inflammatory bowel disease30.0CD79A
7arthritis29.8VIPR1, PHB2
8dermatitis29.8CD79A
9neuropathy29.8CD79A
10cholera10.2
11typhoid fever10.2
12protozoal dysentery10.1
13campylobacteriosis10.1
14irritable bowel syndrome10.1
15acute diarrhea10.0
16ulcerative colitis10.0
17paratyphoid fever10.0
18hemolytic-uremic syndrome10.0
19phlebotomus fever10.0CCDC130
20herpes zoster10.0TMPO
21acquired immunodeficiency syndrome10.0WARS
22multiple sclerosis10.0TMPO
23severe acute respiratory syndrome10.0SENP6
24polycythemia vera10.0IFNA2
25pancreatic cancer10.0IGF1
26schistosomiasis10.0CD79A
27sinusitis10.0CD79A
28lactose intolerance10.0
29cerebral primitive neuroectodermal tumor10.0ENO2
30hypothyroidism10.0TMPO, IGF1
31bronchitis10.0CD79A
32pheochromocytoma10.0VIPR1, ENO2
33wilson disease10.0TF
34protein-losing enteropathy10.0TF
35adenocarcinoma10.0ENO2, VIPR1
36rheumatoid arthritis10.0TMPO, CD79A
37urethritis10.0CD79A, PHB2
38arthropathy10.0TF, PHB2
39membranoproliferative glomerulonephritis10.0CD79A, IFNA2
40leukopenia10.0TMPO, CD79A, IFNA2
41protein-energy malnutrition10.0IGF1, TF
42siderosis10.0TF
43nephrotic syndrome10.0TF, CD79A
44liver cirrhosis10.0TF, IFNA2, VIPR1
45hepatitis10.0TF, IFNA2, VIPR1
46lipoid nephrosis10.0CD79A, TF
47hepatitis c10.0TF, IFNA2, VIPR1
48galactosemia10.0CD79A, IGF1, TF
49primary hyperoxaluria10.0TF, IGF1, CD79A
50diabetes mellitus10.0TF, IGF1, CD79A

Graphical network of the top 20 diseases related to Dysentery:



Diseases related to dysentery

Clinical Features for Dysentery

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Drugs & Therapeutics for Dysentery

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Dysentery

Search NIH Clinical Center for Dysentery

Search CenterWatch for Dysentery

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Dysentery

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Anatomical Context for Dysentery

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32MalaCards
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MalaCards organs/tissues related to Dysentery:

32
Colon, Testes, Liver, Bone, Bone marrow, Breast, Small intestine

Animal Models for Dysentery or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Dysentery:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.9PELO, TMPO, ENO2, CD79A, QTRT1, IGF1

Publications for Dysentery

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50PubMed
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Articles related to Dysentery:

(show top 50)    (show all 499)
idTitleAuthorsYear
1
Amoebic dysentery. (23991750)
2013
2
Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with "Brachyspira hampsonii" strain 30446. (23460829)
2013
3
Antibiotics for the treatment of dysentery in children. (20348130)
2010
4
Trichuris dysentery syndrome with eosinophilic leukemoid reaction mimicking inflammatory bowel disease. (19242090)
2009
5
Immunological alterations during the clinical and recovery phases of experimental swine dysentery. (16772410)
2006
6
Amoebic dysentery. (16973041)
2006
7
Trend and disease burden of bacillary dysentery in China (1991-2000). (16878230)
2006
8
Reflections on my studies of the effects of sulphonamide drugs in bacillary dysentery in Egypt, 1943-1944. (16893944)
2006
9
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. (16275786)
2005
10
Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis. (15247174)
2004
11
Clinical dysentery in hospitalized children. (12120936)
2002
12
A new biological agent for treatment of Shiga toxigenic Escherichia coli infections and dysentery in humans. (10700227)
2000
13
Contribution to the ethnobotanical, phytochemical and pharmacological studies of traditionally used medicinal plants in the treatment of dysentery and diarrhoea in Lomela area, Democratic Republic of Congo (DRC). (10940578)
2000
14
Detection and isolation of coronavirus from feces of three herds of feedlot cattle during outbreaks of winter dysentery-like disease. (11043691)
2000
15
Isolation, oxygen sensitivity, and virulence of NADH oxidase mutants of the anaerobic spirochete Brachyspira (Serpulina) hyodysenteriae, etiologic agent of swine dysentery. (10543819)
1999
16
Growth and development four years after treatment for the Trichuris dysentery syndrome. (9894824)
1998
17
A household survey of dysentery in Burundi: implications for the current pandemic in sub-Saharan Africa. (9141750)
1997
18
Epidemic shigella dysentery in children in northern KwaZulu-Natal. (9063314)
1997
19
Utility of a polymerase chain reaction diagnostic system in a study of the epidemiology of shigellosis among dysentery patients, family contacts, and well controls living in a shigellosis-endemic area. (9333160)
1997
20
Etiology of bloody diarrhea in Bolivian children: implications for empiric therapy. Bolivian Dysentery Study Group. (9180200)
1997
21
Medical practitioners' knowledge of dysentery treatment in Bangladesh. (8696198)
1996
22
'Catch-up' growth velocities after treatment for Trichuris dysentery syndrome. (8594685)
1995
23
Detection of bovine coronavirus and type A rotavirus in neonatal calf diarrhea and winter dysentery of cattle in Quebec: evaluation of three diagnostic methods. (8055431)
1994
24
Ulcerative colitis developing after amoebic dysentery in a haemophiliac patient with AIDS. (1568665)
1992
25
Mortality associated with acute watery diarrhea, dysentery and persistent diarrhea in rural North India. (12286021)
1992
26
A cytotoxic haemolysin from Treponema hyodysenteriae--a probable virulence determinant in swine dysentery. (1990146)
1991
27
Acute glomerulonephritis due to Shigella flexneri dysentery with demonstration of a virulence protein of Shigella in circulating immune complexes. (2405072)
1990
28
Fatal dysentery in rural Bangladesh. (2229985)
1990
29
General considerations in the management of typhoid fever and dysentery. (2694338)
1989
30
Diagnosis and management of dysentery by community health workers. (2900931)
1988
31
Epidemic shiga bacillary dysentery in Rangoon, Burma, 1984/85. (2861376)
1985
32
Treatment of severe bacillary dysentery with trimethoprim alone. (3890282)
1985
33
Recent dysentery and gastroenteritis outbreak in some areas of Hooghly Distt. (West Bengal). (3835186)
1985
34
Epidemic bacillary dysentery in West Bengal, India, 1984. (6145892)
1984
35
A dysentery epidemic in New Guinea and its mortality. (11617438)
1984
36
Epidemic Shiga bacillus dysentery in Central Africa. (6391226)
1984
37
Dysentery caused by Balantidium coli--report of two cases. (6884287)
1983
38
A report of reactive arthritis following dysentery in 1743. (7247979)
1981
39
Immune processes in the course of infection with dysentery bacilli. IV. Transfer of immunity by means of fractions isolated from sera of mice immunized with dysentery bacilli. (7004396)
1980
40
Comparison of selective culture and serologic agglutination of Treponema hyodysenteriae for diagnosis of swine dysentery. (7361391)
1980
41
Comparison of selective culture and serologic agglutination of Treponema hyodysenteriae for diagnosis of swine dysentery. (516340)
1979
42
Use of oral vaccines in attempts to prevent swine dysentery. (260870)
1979
43
Fifty years ago. Paper published in the December issue 1925. A review of a recent epidemic of bacillary dysentery with special reference to a new therapy: a paper read before the Uganda branch of the British Medical Association, March 1925. (391538)
1979
44
Clinico-therapeutic aspects of acute bacillary dysentery in children (a hospital study). (711265)
1978
45
Swine dysentery: studies of gnotobiotic pigs inoculated with Treponema hyodysenteriae, Bacteroides vulgatus, and Fusobacterium necrophorum. (624669)
1978
46
In vitro antitreponemal activities of carbadox, virginiamycin, olaquindox, and tylosin as indices of their effectiveness for preventing swine dysentery. (418551)
1978
47
Immune processes induced by dysentery bacilli in mice. (373684)
1978
48
Efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs. (879561)
1977
49
A study of swine dysentery by immunofluorescence and histology. (335630)
1977
50
The use of dimetridazole in the sow herd for swine dysentery control: a preliminary field report. (599531)
1977

Genetic Variations for Dysentery

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Expression for genes affiliated with Dysentery

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dysentery

Search GEO for disease gene expression data for Dysentery.

Pathways for genes affiliated with Dysentery

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29KEGG
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Pathways related to Dysentery according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7ENO2, IGF1, TF

Compounds for genes affiliated with Dysentery

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44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 28IUPHAR, 24HMDB
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Compounds related to Dysentery according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1mizoribine4410.4IFNA2, CD79A
2polyvinyl alcohol4410.4IFNA2, IGF1
3nandrolone decanoate44 1111.3IGF1, TF
4gamma globulin4410.2IFNA2, CD79A
5starch4410.2IGF1, TF, IFNA2
6betacarotene4410.1IFNA2, TF, CD79A
7vitamin b124410.1CD79A, IGF1, TF
8megestrol acetate4410.0IGF1, IFNA2
9polyethylene glycol4410.0CD79A, TF, IFNA2
10ribavirin44 49 1112.0VIPR1, IFNA2, TF
11octreotide44 59 28 1113.0IFNA2, IGF1, ENO2
12thyroxine44 2411.0IFNA2, TF, IGF1, CD79A
13alpha tocopherol449.9IFNA2, TF, IGF1
14prednisolone44 28 1111.8CD79A, TF, IFNA2
15acth449.8TMPO, ENO2, IGF1, IFNA2
16galactose449.8CD79A, GALM, IFNA2
17indomethacin44 59 28 1112.7IFNA2, CD79A, ENO2, TMPO
18tuberculin449.6CD79A, ENO2
19anticodon449.6WARS, QTRT1
20dopamine44 28 11 2412.6ENO2, CD79A, IGF1, TF, IFNA2
21estrogen449.0ENO2, CD79A, IGF1, PHB2, TF, IFNA2
22alanine448.9ENO2, CD79A, TF, WARS, IFNA2, VIPR1
23glucose448.4VIPR1, IFNA2, GALM, UGGT1, IGF1, ENO2

GO Terms for genes affiliated with Dysentery

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Products for genes affiliated with Dysentery

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Sources for Dysentery

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet