MCID: DYS015
MIFTS: 40

Dysentery malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Dysentery

Aliases & Descriptions for Dysentery:

Name: Dysentery 12 42 14 69
Infectious Diarrhea 12 52

Classifications:



Summaries for Dysentery

Disease Ontology : 12 An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in severe diarrhea with passage of mucus and blood.

MalaCards based summary : Dysentery, also known as infectious diarrhea, is related to typhoid fever and megacolon, and has symptoms including diarrhea An important gene associated with Dysentery is TF (Transferrin). The drugs Loperamide and Omeprazole have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and liver.

Wikipedia : 71 Dysentery is a type of gastroenteritis that results in diarrhea with blood. Other symptoms may include... more...

Related Diseases for Dysentery

Diseases related to Dysentery via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
id Related Disease Score Top Affiliating Genes
1 typhoid fever 29.5 ALB CD40LG CD79A
2 megacolon 29.3 CD40LG CD79A IFNA2
3 protozoal dysentery 12.0
4 amebiasis 11.9
5 shigellosis 11.4
6 campylobacteriosis 11.0
7 balantidiasis 10.8
8 phaeochromocytoma 10.3 ALB TTR
9 ehlers-danlos syndrome, periodontal type 1 10.3 ALB TTR
10 shoulder impingement syndrome 10.3 ALB CRP
11 acro coxo mesomelic dysplasia 10.3 CRP HP
12 atopic dermatitis 6 10.3 ALB CD79A
13 chronic myelomonocytic leukemia 10.3 HP TTR
14 schneiderian carcinoma 10.3 ALB CD79A
15 hemoglobin c disease 10.3 CRP HP TF
16 female infertility of uterine origin 10.3 ALB TF TTR
17 sutton disease 2 10.3 LTF TF
18 bile duct mucoepidermoid carcinoma 10.2 ALB CRP TF
19 cataract 10.2 ALB CRP TTR
20 erythema infectiosum 10.2 ALB CRP TTR
21 rosette-forming glioneuronal tumor of fourth ventricule 10.2 LTF TF
22 pigmentation disease 10.2 ALB HP TF
23 acute female pelvic peritonitis 10.2 CD79A TTR
24 aortic valve prolapse 10.2 ALB HP TTR
25 diarrhea 10.2
26 toxic optic neuropathy 10.2 CD79A IL1A
27 anogenital venereal wart 10.2 ALB CRP TTR
28 malignant hyperthermia susceptibility 1 10.2 ALB CD79A TF
29 body dysmorphic disorder 10.2 ALB CRP TTR
30 capillary leak syndrome 10.2 ALB CRP
31 retinal arterial macroaneurysm with supravalvular pulmonic stenosis 10.2 ALB CRP TF TTR
32 blind hypotensive eye 10.2 CRP LTF TF
33 uterine ligament clear cell adenocarcinoma 10.2 ALB CD79A CRP
34 paranasal sinus sarcoma 10.2 ALB CD79A TTR
35 central nervous system leiomyoma 10.2 ALB CRP TF TTR
36 neuronal ceroid-lipofuscinoses 10.2 ALB CRP HP TF
37 chronic myocardial ischemia 10.1 ALB CRP TF TTR
38 ciliary discoordination, due to random ciliary orientation 10.1 ALB CD79A IL1A
39 villonodular synovitis 10.1 CRP ENO2
40 focal epithelial hyperplasia 10.1 ALB HP TF TTR
41 swine influenza 10.1 CRP IL1A
42 bile duct adenocarcinoma 10.1 ALB CD40LG
43 paragonimiasis 10.1 ALB HP LTF
44 estrogen excess 10.1 ALB CD40LG
45 familial nephrotic syndrome 10.1 ALB CD79A CRP TF
46 infertility due to extratesticular cause 10.1 ALB CD79A LTF
47 freiberg's disease 10.1 ALB CD40LG
48 histiocytosis 10.1 CD79A CRP IL1A
49 male genital organ stricture 10.1 ALB CD79A TF TTR
50 bladder sarcoma 10.1 ALB CD79A TF TTR

Comorbidity relations with Dysentery via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Dysentery:



Diseases related to Dysentery

Symptoms & Phenotypes for Dysentery

UMLS symptoms related to Dysentery:


diarrhea

Drugs & Therapeutics for Dysentery

Drugs for Dysentery (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 120)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Loperamide Approved Phase 4,Phase 3 53179-11-6 3955
2
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
3
Azithromycin Approved Phase 4 83905-01-5 55185 53477736 447043
4
Piperazine Approved, Vet_approved Phase 4 110-85-0 4837
5
Mebendazole Approved, Vet_approved Phase 4 31431-39-7 4030
6
Rifaximin Approved, Investigational Phase 4,Phase 2,Phase 3 80621-81-4 6436173
7
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
8 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
9 Anti-Infective Agents Phase 4,Phase 2,Phase 3
10 Antiparasitic Agents Phase 4,Phase 3,Phase 2
11 rifamycin SV Phase 4,Phase 2,Phase 3
12
Proton pump inhibitors Phase 4
13 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
14 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 2,Phase 3
15 Antacids Phase 4,Phase 1
16 Anthelmintics Phase 4
17 Piperazine citrate Phase 4
18 Antidiarrheals Phase 4,Phase 3
19 Anti-Ulcer Agents Phase 4,Phase 1
20 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3
21 Rifamycins Phase 4,Phase 2,Phase 3
22 Antimitotic Agents Phase 4
23 Clavulanic Acid Phase 4
24 Amoxicillin-Potassium Clavulanate Combination Phase 4
25 beta-Lactamase Inhibitors Phase 4
26 Antitubercular Agents Phase 4
27 Acidophilus Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2
28 Citrate Nutraceutical Phase 4
29
Citric Acid Nutraceutical, Vet_approved Phase 4 77-92-9 311
30 Cola Nutraceutical Phase 4
31
Ciprofloxacin Approved, Investigational Phase 3,Phase 2 85721-33-1 2764
32
Zinc Approved Phase 3,Phase 2 7440-66-6 32051 23994
33
Iron Approved Phase 3,Phase 2 7439-89-6 23925
34
Prednisolone Approved, Vet_approved Phase 3,Phase 2 50-24-8 5755
35
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2 83-43-2 6741
36
Nitazoxanide Approved, Investigational, Vet_approved Phase 3,Phase 2 55981-09-4 41684
37 Zinc sulfate Approved Phase 3 7733-02-0
38
Irinotecan Approved, Investigational Phase 3 97682-44-5, 100286-90-6 60838
39
Lactulose Approved Phase 2, Phase 3 4618-18-2 11333
40
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
41
leucovorin Approved, Nutraceutical Phase 3 58-05-9 54575, 6560146 143
42
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
43 Cytochrome P-450 CYP1A2 Inhibitors Phase 3,Phase 2
44 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 2
45 Topoisomerase Inhibitors Phase 3,Phase 2
46 Prednisolone acetate Phase 3,Phase 2
47 glucocorticoids Phase 3,Phase 2
48 Neuroprotective Agents Phase 3,Phase 2
49 Hematinics Phase 3
50 Dermatologic Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 93)
id Name Status NCT ID Phase
1 New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Diarrhea Management– Surveillance Study for Adverse Effects Completed NCT00490932 Phase 4
2 Effects of Gastric Acid on Colonic Microbiome Completed NCT01901276 Phase 4
3 Azithromycin, With or Without Loperamide, to Treat Travelers' Diarrhea Completed NCT00359970 Phase 4
4 Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea Completed NCT00292344 Phase 4
5 Study to Evaluate Efficacy and Safety of a Double Treatment Plan Using a Combination of Mebendazole and Quinfamide for Treating Intestinal Helminthiasis and Amebiasis in the Mexican Population Completed NCT02385058 Phase 4
6 Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial Recruiting NCT02871908 Phase 4
7 Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children Not yet recruiting NCT02765217 Phase 4
8 Improving Bowel Habits of Elderly With Probiotics and Non-probiotics Not yet recruiting NCT02949882 Phase 4
9 Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea Terminated NCT01972932 Phase 4
10 Probiotics and the Prevention of Traveler's Diarrhea Terminated NCT01005849 Phase 4
11 Single Daily Dose Rifaximin for the Treatment of Travelers' Diarrhea Withdrawn NCT00875875 Phase 4
12 Randomized Controlled Field Trial of a Probiotics to Assess Its Role in Preventig Diarrhoea Unknown status NCT00534170 Phase 3
13 Efficacy of Rifaximin in Preventing Campylobacteriosis Completed NCT02280044 Phase 2, Phase 3
14 Rifamycin SV-MMX® Tablets Versus Ciprofloxacin Capsules in Acute Traveller's Diarrhoea Completed NCT01208922 Phase 3
15 Safety, Immunogenicity and Efficacy of Shigella Conjugate Vaccines in 1-4 Year Olds in Israel Completed NCT00368316 Phase 3
16 Impact of Sprinkles on Infectious Morbidity When Moderate to Severe Pediatric Malnutrition Is Highly Prevalent Completed NCT00530374 Phase 3
17 Community Trial of Zinc Supplementation on Preschool Child Mortality and Morbidity in Southern Nepal Completed NCT00109551 Phase 3
18 Fermented Milk and Fermented Rice on the Appearance of Respiratory and Gastrointestinal Symptoms Completed NCT01909128 Phase 3
19 Vitamin A Supplementation in Newborns Study Completed NCT00114868 Phase 3
20 Zinc Supplementation in Shigella Patients Completed NCT00321126 Phase 3
21 Study of Nitazoxanide in the Treatment of Amebiasis in Children Completed NCT00366730 Phase 3
22 Study of Nitazoxanide in the Treatment of Amebiasis in Adults and Adolescents Completed NCT00366236 Phase 3
23 Study to Evaluate Safety and Efficacy of Rifamycin SV Multi-Matrix System (MMX) for the Treatment of Traveler's Diarrhea (TD) Completed NCT01142089 Phase 3
24 Travelers' Diarrhea (TD) Vaccine Pivotal Efficacy Study Completed NCT00993681 Phase 3
25 Rifaximin for Prevention of Travellers' Diarrhea Completed NCT00742469 Phase 3
26 Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults Completed NCT00737412 Phase 3
27 Prevention of Travelers' Diarrhea in Subjects Traveling Outside the U.S. Completed NCT00328380 Phase 3
28 Nitazoxanide Plus Lactulose Versus Lactulose Alone Treatment of Hepatic Encephalopathy Recruiting NCT02464124 Phase 2, Phase 3
29 Prevention of Irinotecan Induced Diarrhea by Probiotics Recruiting NCT02819960 Phase 3
30 A Study Comparing Two Rifaximin Tablets in Patients With Travelers' Diarrhea. Recruiting NCT02920242 Phase 3
31 Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial Not yet recruiting NCT02473341 Phase 3
32 Clinical Trial of CBS-2004 (Bimuno)® in Prevention of Travelers' Diarrhea Not yet recruiting NCT02736539 Phase 3
33 A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Difficile-associated Diarrhea Terminated NCT00466635 Phase 3
34 A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin in the Treatment of Plague in Humans Unknown status NCT01243437 Phase 2
35 Probiotics for Infectious Diarrhea in Children in South India Completed NCT01130792 Phase 1, Phase 2
36 Isoleucine Added ORS in Children With Diarrhoea Completed NCT01034228 Phase 2
37 Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of Protection Completed NCT00485134 Phase 1, Phase 2
38 Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate Completed NCT01080716 Phase 1, Phase 2
39 Effect of Irvingia Gabonensis Administration on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity Completed NCT02354339 Phase 2
40 A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults Completed NCT02676895 Phase 2
41 Therapeutic Induction of Endogenous Antibiotics Completed NCT00800930 Phase 2
42 Healthy Adult Volunteer Study for Two Doses of a Shigella Vaccine Completed NCT00210288 Phase 2
43 Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis. Completed NCT02265328 Phase 2
44 Traveler's Diarrhea (TD) Vaccine Asia Efficacy Study Completed NCT01040325 Phase 2
45 Traveler's Diarrhea (TD) Automated Process Completed NCT00751777 Phase 2
46 Rifaximin Versus Placebo in the Prevention of Travelers' Diarrhea Completed NCT00098384 Phase 2
47 A Study of the Absorption of GT267-004 in Patients With Clostridium Difficile-Associated Diarrhea Completed NCT00382304 Phase 2
48 A Study of GT160-246 Versus Vancomycin in Patients With Clostridium Difficile-Associated Diarrhea Completed NCT00034294 Phase 2
49 Safety, Immunogenicity and Efficacy Study of Inactivated Whole Cell Shigella Flexneri 2a Vaccine With and Without dmLT in Adults Recruiting NCT03038243 Phase 2
50 Auranofin Trial for GI Protozoa Recruiting NCT02736968 Phase 2

Search NIH Clinical Center for Dysentery

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: dysentery

Genetic Tests for Dysentery

Anatomical Context for Dysentery

MalaCards organs/tissues related to Dysentery:

39
Colon, Testes, Liver, Neutrophil, Bone, Breast, Small Intestine

Publications for Dysentery

Articles related to Dysentery:

(show top 50) (show all 545)
id Title Authors Year
1
Identification of weather variables sensitive to dysentery in disease-affected county of China. ( 27742060 )
2017
2
Neither plague nor malaria, but dysentery as a cause of death for St. Louis. ( 26759133 )
2016
3
The Use of an Autoregressive Integrated Moving Average Model for Prediction of the Incidence of Dysentery in Jiangsu, China. ( 27106828 )
2016
4
Swine Dysentery: Etiopathogenesis and Diagnosis of a Reemerging Disease. ( 27288432 )
2016
5
Anisakiasis Causing Acute Dysentery in Malaysia. ( 27325803 )
2016
6
Comparison of Brachyspira hyodysenteriae Isolates Recovered from Pigs in Apparently Healthy Multiplier Herds with Isolates from Herds with Swine Dysentery. ( 27489956 )
2016
7
Lethality of First Contact Dysentery Epidemics on Pacific Islands. ( 27185765 )
2016
8
Quantifying the Impact of Floods on Bacillary Dysentery in Dalian City, China, From 2004 to 2010. ( 27229186 )
2016
9
Quantitative analysis of burden of bacillary dysentery associated with floods in Hunan, China. ( 26780145 )
2016
10
Association between flood and the morbidity of bacillary dysentery in Zibo City, China: a symmetric bidirectional case-crossover study. ( 27121465 )
2016
11
The changing epidemiology of bacillary dysentery and characteristics of antimicrobial resistance of Shigella isolated in China from 2004-2014. ( 27863468 )
2016
12
Association between meteorological factors and bacillary dysentery incidence in Chaoyang city, China: an ecological study. ( 27940632 )
2016
13
Daily temperature change in relation to the risk of childhood bacillary dysentery among different age groups and sexes in a temperate city in China. ( 26655018 )
2016
14
Distributed lag effects and vulnerable groups of floods on bacillary dysentery in Huaihua, China. ( 27427387 )
2016
15
Efficacy of Synbiotics for Treatment of Bacillary Dysentery in Children: A Double-Blind, Randomized, Placebo-Controlled Study. ( 28042600 )
2016
16
Patterns of Bacillary Dysentery in China, 2005-2010. ( 26828503 )
2016
17
An Investigation into the Etiological Agents of Swine Dysentery in Australian Pig Herds. ( 27907102 )
2016
18
Spatio-Temporal Pattern and Socio-Economic Factors of Bacillary Dysentery at County Level in Sichuan Province, China. ( 26469274 )
2015
19
The Rising Dominance of Shigella sonnei: An Intercontinental Shift in the Etiology of Bacillary Dysentery. ( 26068698 )
2015
20
Nonlinear and threshold of the association between meteorological factors and bacillary dysentery in Beijing, China. ( 26027678 )
2015
21
PREDICTING CLINICALLY DIAGNOSED DYSENTERY INCIDENCE OBTAINED FROM MONTHLY CASE REPORTING BASED ON METEOROLOGICAL VARIABLES IN DALIAN, LIAONING PROVINCE, CHINA, 2005-2011 USING A DEVELOPED MODEL. ( 26513932 )
2015
22
Analysis of Risk and Burden of Dysentery Associated with Floods from 2004 to 2010 in Nanning, China. ( 26416103 )
2015
23
High mean water vapour pressure promotes the transmission of bacillary dysentery. ( 25946209 )
2015
24
The association between diurnal temperature range and childhood bacillary dysentery. ( 26045331 )
2015
25
Burden of major diarrheagenic protozoan parasitic co-infection among amoebic dysentery cases from North East India: a case report. ( 26099490 )
2015
26
Sequence types and pleuromutilin susceptibility of Brachyspira hyodysenteriae isolates from Italian pigs with swine dysentery: 2003-2012. ( 25486860 )
2015
27
Trichuris dysentery syndrome: Do we learn enough from case studies? ( 26695216 )
2015
28
Meteorological variables and bacillary dysentery cases in Changsha City, China. ( 24591435 )
2014
29
Effects of the floods on dysentery in north central region of Henan Province, China from 2004 to 2009. ( 24955987 )
2014
30
Misdiagnosed amoebic colitis leading to severe dysentery and necrotizing colitis--report of a case and review of the literature. ( 24450838 )
2014
31
Dysentery in World War 1: Shigella a century on. ( 25441185 )
2014
32
Spatial-temporal pattern and risk factor analysis of bacillary dysentery in the Beijing-Tianjin-Tangshan urban region of China. ( 25257255 )
2014
33
Effect of zinc chelate and valnemulin for the treatment of swine dysentery in an experimental challenge study. ( 24287025 )
2014
34
Aetiology and clinical features of dysentery in children aged <5 years in rural Bangladesh. ( 23561052 )
2014
35
Discrimination of Entamoeba Spp. in children with dysentery. ( 25120897 )
2014
36
Shewanella dysentery in a patient with underlying malignancy. ( 25934962 )
2014
37
Bacillary dysentery from World War 1 and NCTC1, the first bacterial isolate in the National Collection. ( 25441203 )
2014
38
Genomic analysis of the emergence of 20th century epidemic dysentery. ( 24886041 )
2014
39
Should school-age children not attending school and adults aged 20-44 years be considered high-risk group for bacillary dysentery infection in Guangzhou, China? A review of 4,775 bacillary dysentery cases. ( 24879009 )
2014
40
Socio-economic factors of bacillary dysentery based on spatial correlation analysis in Guangxi Province, China. ( 25036182 )
2014
41
The extant World War 1 dysentery bacillus NCTC1: a genomic analysis. ( 25441199 )
2014
42
Temperature and atmospheric pressure may be considered as predictors for the occurrence of bacillary dysentery in Guangzhou, Southern China. ( 25075491 )
2014
43
Comparison of Lesion Severity, Distribution, and Colonic Mucin Expression in Pigs With Acute Swine Dysentery Following Oral Inoculation With "Brachyspira hampsonii" or Brachyspira hyodysenteriae. ( 24577722 )
2014
44
Isolation and development of bioluminescent reporter phages for bacterial dysentery. ( 25252629 )
2014
45
Spatiotemporal pattern of bacillary dysentery in China from 1990 to 2009: what is the driver behind? ( 25093593 )
2014
46
Impacts of floods on dysentery in Xinxiang city, China, during 2004-2010: a time-series Poisson analysis. ( 25098726 )
2014
47
Application of a novel grey self-memory coupling model to forecast the incidence rates of two notifiable diseases in China: dysentery and gonorrhea. ( 25546054 )
2014
48
Amoebic dysentery. ( 23991750 )
2013
49
Correlation analysis for the attack of bacillary dysentery and meteorological factors based on the Chinese medicine theory of Yunqi and the medical-meteorological forecast model. ( 22903445 )
2013
50
Swine dysentery: aetiology, pathogenicity, determinants of transmission and the fight against the disease. ( 23665849 )
2013

Variations for Dysentery

Expression for Dysentery

Search GEO for disease gene expression data for Dysentery.

Pathways for Dysentery

GO Terms for Dysentery

Cellular components related to Dysentery according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.76 ALB CRP ENO2 HP LTF PHB2
2 extracellular region GO:0005576 9.65 ALB CD40LG CRP HP IFNA2 IL1A
3 extracellular space GO:0005615 9.36 ALB CD40LG CRP ENO2 HP IFNA2

Biological processes related to Dysentery according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.62 CD40LG CRP IFNA2 IL1A
2 cellular protein metabolic process GO:0044267 9.46 ALB LTF TF TTR
3 B cell differentiation GO:0030183 9.43 CD40LG CD79A IFNA2
4 retina homeostasis GO:0001895 9.13 ALB LTF TF
5 B cell proliferation GO:0042100 8.8 CD40LG CD79A IFNA2

Molecular functions related to Dysentery according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.44 ALB CD40LG CD79A CRP ENO2 HP

Sources for Dysentery

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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