MCID: DYS015
MIFTS: 49

Dysentery malady

Gastrointestinal diseases category
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Summaries for Dysentery

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in severe diarrhea with passage of mucus and blood.

MalaCards: Dysentery, also known as infectious diarrhea, is related to deficiency anemia and diarrhea. An important gene associated with Dysentery is TMPO (thymopoietin), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Hemostasis. The drugs ciprofloxacin and scopolamine and the compounds mizoribine and gamma globulin have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and liver, and related mouse phenotype cellular.

Wikipedia:65 Dysentery is diarrhea which contains blood. Other symptoms may include fever, abdominal pain, and rectal... more...

Aliases & Classifications for Dysentery

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 35MeSH, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

dysentery 8 10 62
infectious diarrhea 8 45


Related Diseases for Dysentery

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17GeneCards, 18GeneDecks
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Diseases related to Dysentery via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1deficiency anemia29.8CD79A, IFNA2, TMPO, TF
2diarrhea10.6
3shigellosis10.4
4amebiasis10.3
5cholera10.3
6gastroenteritis10.2
7irritable bowel syndrome10.2
8campylobacteriosis10.2
9protozoal dysentery10.2
10pneumonia10.2
11blindness10.2
12ulcerative colitis10.1
13paratyphoid fever10.1
14hemolytic-uremic syndrome10.1
15typhoid fever10.1
16inflammatory bowel disease10.1
17mumps10.1CD79A
18purpura10.1CD79A
19bronchitis10.1CD79A
20protein-losing enteropathy10.1TF
21siderosis10.1TF
22urethritis10.0PHB2, CD79A
23hepatitis b10.0TMPO, IFNA2
24viral hepatitis10.0IFNA2, TMPO
25ankylosing spondylitis10.0CD79A, PHB2
26membranoproliferative glomerulonephritis10.0CD79A, IFNA2
27cryoglobulinemia10.0IFNA2, CD79A
28hypothyroidism10.0IGF1, TMPO
29polyneuropathy10.0CD79A, IFNA2
30carcinoid syndrome10.0ENO2, IFNA2
31transitional cell carcinoma10.0IFNA2, ENO2
32arthropathy10.0PHB2, TF
33vasculitis10.0CD79A, IFNA2
34eosinophilia10.0CD79A, IFNA2
35lactose intolerance10.0
36protein-energy malnutrition10.0IGF1, TF
37congenital stationary night blindness, type 1f10.0IFNA2, TF
38hemolytic anemia10.0TF, IFNA2
39uremia10.0IGF1, TF
40lipoid nephrosis10.0CD79A, TF
41hypogonadism10.0IGF1, TF
42hepatitis10.0IFNA2, TF
43leukopenia10.0TMPO, IFNA2, CD79A
44type 1 diabetes mellitus10.0CD79A, TMPO, IGF1
45diphtheria10.0TF, CD79A
46myelodysplastic syndromes10.0TMPO, TF
47nephrotic syndrome10.0CD79A, TF
48congenital heart disease10.0IGF1, CD79A
49hepatitis c10.0IFNA2, TF
50myeloma10.0IGF1, IFNA2, CD79A

Graphical network of the top 20 diseases related to Dysentery:



Diseases related to dysentery

Symptoms for Dysentery

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Drugs & Therapeutics for Dysentery

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Dysentery

Search NIH Clinical Center for Dysentery

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Dysentery

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Anatomical Context for Dysentery

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33MalaCards
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MalaCards organs/tissues related to Dysentery:

33
Colon, Testes, Liver, Bone marrow, Bone, Small intestine, Breast

Animal Models for Dysentery or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Dysentery:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.7CD79A, PHB2, ENO2, TMPO, IGF1

Publications for Dysentery

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Sources:
52PubMed
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Articles related to Dysentery:

(show top 50)    (show all 494)
idTitleAuthorsYear
1
Plants used for treatment of dysentery and diarrhoea by the Bhoxa community of district Dehradun, Uttarakhand, India. (24432368)
2013
2
Correlation analysis for the attack of bacillary dysentery and meteorological factors based on the Chinese medicine theory of Yunqi and the medical-meteorological forecast model. (22903445)
2013
3
Comment on "Randomized intervention study of solar disinfection of drinking water in the prevention of dysentery in Kenyan children aged under 5 years". (22300543)
2012
4
Severe chronic iron deficiency anaemia secondary to Trichuris dysentery syndrome - a case report. (23202608)
2012
5
Child dysentery in the Limpopo Valley: a cohort study of water, sanitation and hygiene risk factors. (19240352)
2009
6
Application of real time PCR for diagnosis of Swine Dysentery. (19346708)
2009
7
Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilli in vivo and in vitro. (15587409)
2004
8
Coleridge's choleras: cholera morbus, Asiatic cholera, and dysentery in early nineteenth-century England. (12955962)
2003
9
Clinical dysentery in hospitalized children. (12120936)
2002
10
Fifty years of dysentery research at the PAccs University. (11791353)
2001
11
A household survey of dysentery in Burundi: implications for the current pandemic in sub-Saharan Africa. (9141750)
1997
12
The influence of breast feeding on the occurrence of dysentery, persistent diarrhoea and malnutrition among Nigerian children with diarrhoea. (9133818)
1997
13
Efficiency of EPI cluster sampling for assessing diarrhoea and dysentery prevalence. (9447775)
1997
14
Infection and cross-protection studies of winter dysentery and calf diarrhea bovine coronavirus strains in colostrum-deprived and gnotobiotic calves. (8720237)
1996
15
Medical practitioners' knowledge of dysentery treatment in Bangladesh. (8696198)
1996
16
Azithromycin prophylaxis prevents epidemic dysentery. (8758091)
1996
17
Dual flaA1 flaB1 mutant of Serpulina hyodysenteriae expressing periplasmic flagella is severely attenuated in a murine model of swine dysentery. (8926083)
1996
18
An outbreak of dysentery in Zambia. (8685797)
1996
19
The effects of health services utilization on the recovery from dysentery. (8820619)
1996
20
Infection, diarrhea, and dysentery caused by Shigella species and Campylobacter jejuni among Guatemalan rural children. (8177630)
1994
21
You're the flight surgeon: a case of amoebic dysentery. (7872923)
1994
22
Shigella-specific IgA in saliva of children with bacillary dysentery. (1547024)
1992
23
Diarrhoea, dysentery, and food poisoning. (1392948)
1992
24
Dysentery surveillance. (1669852)
1991
25
Dysentery surveillance. (1669861)
1991
26
Prevention of diarrhoea and dysentery by hand washing. (2603190)
1989
27
The research on the acupuncture treatment of acute bacillary dysentery. (22557609)
1988
28
Winter dysentery in adult dairy cattle: detection of coronavirus in the faeces. (2848350)
1988
29
Studies on the efficacy of Getroxel against Treponema hyodysenteriae and its role in the control of swine dysentery. (3447462)
1987
30
Outbreak of dysentery due to Shigella flexneri type 2a. (3333777)
1987
31
Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9). (3535233)
1986
32
Comparison of minimum inhibitory concentration of water soluble extracts of eugenia jambolana lam. (Fam. Myrtaceae) barks of different ages on dysentery and diarrhoea forming micro - organisms. (22557509)
1985
33
Bacillary dysentery. (6386299)
1984
34
Further contributions towards the ethnobotany of madhya pradesh 2: plants used against diarrhoea and dysentery. (22556976)
1983
35
Dysentery form gastroenteritis in infancy. (6275330)
1981
36
Comparison of lincomycin and carbadox for treatment and control of swine dysentery. (7254186)
1981
37
Eradication of swine dysentery from closed pig herds. (7292933)
1981
38
Pathogenesis and lesions of swine dysentery induced by artificial methods in early weaned pigs. (7008329)
1980
39
Carbadox vs lincomycin in swine dysentery control. (7354759)
1980
40
Immune processes in the course of infection with dysentery bacilli. IV. Transfer of immunity by means of fractions isolated from sera of mice immunized with dysentery bacilli. (7004396)
1980
41
Comparison of selective culture and serologic agglutination of Treponema hyodysenteriae for diagnosis of swine dysentery. (516340)
1979
42
Pathological observation on experimental swine dysentery. (522890)
1979
43
Importance of colicinogeny for the course of acute bacillary dysentery. (44941)
1979
44
Masquerading colitis. Infectious dysentery superimposed on chronic inflammatory bowel disease. (271742)
1978
45
The enigma of winter dysentery. (568536)
1978
46
Clinico-therapeutic aspects of acute bacillary dysentery in children (a hospital study). (730279)
1978
47
Influence of diet on experimental swine dysentery. 2. Effects of a vitamin E and selenium deficient diet supplemented with 3% cod liver oil, vitamin E or selenium. (655023)
1978
48
Invasive amebiasis. I. Amebic dysentery and its complications. (195178)
1977
49
Efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs. (879561)
1977
50
Diagnosis of swine dysentery using an absorbed fluorescent antiserum. (335634)
1977

Variations for Dysentery

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Expression for genes affiliated with Dysentery

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dysentery

Search GEO for disease gene expression data for Dysentery.

Pathways for genes affiliated with Dysentery

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50PathCards, 55Reactome, 30KEGG
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Pathways related to Dysentery according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3IGF1, TF
2
Show member pathways
8.9IFNA2, IGF1, TF
38.8ENO2, IGF1, TF

Compounds for genes affiliated with Dysentery

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45Novoseek, 24HMDB, 11DrugBank, 3BitterDB, 51PharmGKB, 29IUPHAR, 61Tocris Bioscience
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Compounds related to Dysentery according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1mizoribine4510.0IFNA2, CD79A
2gamma globulin4510.0CD79A, IFNA2
3inosine45 2410.9IFNA2, TMPO
4isotretinoin45 1110.9IFNA2, CD79A
5dapsone45 3 51 1112.9IFNA2, CD79A
6tuberculin459.9ENO2, CD79A
7polyvinyl alcohol459.9IGF1, IFNA2
8penicillin459.9TF, CD79A
9megestrol acetate459.8IFNA2, IGF1
10cortisone45 2410.8IGF1, TMPO
11con a459.8CD79A, IFNA2
12cellulose acetate459.7CD79A, ENO2
13nandrolone decanoate45 1110.7TF, IGF1
14glutaraldehyde459.7TF, CD79A
15ifosfamide45 1110.7IFNA2, TF
16alginate459.5CD79A, IGF1
17betacarotene459.5TF, IFNA2, CD79A
18polyethylene glycol459.5CD79A, IFNA2, TF
19prednisolone45 29 1111.5CD79A, IFNA2, TF
20agar459.5CD79A, IFNA2, TF
21epinephrine45 24 1111.4CD79A, IFNA2, TF
22ascorbic acid45 2410.4CD79A, IFNA2, TF
23valproate459.4CD79A, IGF1
24sialic acid459.4CD79A, ENO2, TF
25starch459.4TF, IGF1, IFNA2
26octreotide45 61 29 1112.4ENO2, IFNA2, IGF1
27methotrexate51 45 1111.4CD79A, ENO2, TF
28histamine45 29 2411.3TF, IFNA2, CD79A
29alpha tocopherol459.3TF, IGF1, IFNA2
30vitamin b12459.3CD79A, IGF1, TF
31etoposide45 51 61 1112.3IGF1, IFNA2, ENO2
32ribonucleic acid459.3ENO2, IFNA2, IGF1
33norepinephrine45 24 1111.2CD79A, ENO2, TF
34tamoxifen45 51 29 1112.2IFNA2, IGF1, TF
35ibmx45 61 2911.2TF, IGF1, ENO2
36indomethacin45 29 61 1112.2TMPO, IFNA2, ENO2, CD79A
37cyclosporin a45 29 6111.1TF, TMPO, CD79A
38aspartate459.1ENO2, IFNA2, TMPO, TF
39paraffin459.0CD79A, ENO2, TF
40acth459.0ENO2, IFNA2, TMPO, IGF1
41alanine458.9CD79A, ENO2, IFNA2, TF
42thyroxine45 249.9TF, IGF1, IFNA2, CD79A
43glucose458.9IGF1, TMPO, IFNA2, ENO2
44retinoic acid45 249.8IGF1, IFNA2, ENO2, CD79A
45creatinine458.8TF, IGF1, ENO2, CD79A
46iron45 249.7ENO2, IFNA2, TF
47glutamine458.7ENO2, IGF1, TF
48dopamine45 29 24 1111.4TF, IGF1, IFNA2, ENO2, CD79A
49vegf458.4CD79A, ENO2, IFNA2, IGF1, TF
50estrogen457.6CD79A, PHB2, ENO2, IFNA2, IGF1, TF

GO Terms for genes affiliated with Dysentery

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16Gene Ontology
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Cellular components related to Dysentery according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.4ENO2, IFNA2, IGF1, TF

Biological processes related to Dysentery according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet degranulationGO:0025769.3IGF1, TF
2blood coagulationGO:0075968.6IFNA2, IGF1, TF

Products for genes affiliated with Dysentery

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Sources for Dysentery

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet