Aliases & Classifications for Dysgerminoma

About this section
Sources:
10DISEASES, 44Novoseek, 61UMLS
See all sources

Aliases & Descriptions for Dysgerminoma:

Name: Dysgerminoma 10 44 61


Summaries for Dysgerminoma

About this section
Wikipedia:64 A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary. more...

MalaCards based summary: Dysgerminoma is related to gonadoblastoma and hermaphroditism. An important gene associated with Dysgerminoma is PTHLH (parathyroid hormone-like hormone), and among its related pathways are G alpha (s) signalling events and Peptide hormone metabolism. The compounds ag-1296 and clodronate have been mentioned in the context of this disorder. Affiliated tissues include ovary, lymph node and lung, and related mouse phenotypes are tumorigenesis and homeostasis/metabolism.

Related Diseases for Dysgerminoma

About this section

Diseases related to Dysgerminoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1gonadoblastoma31.4KIT, SRY
2hermaphroditism30.8SRY
3turner syndrome30.5SRY, CGA
4teratoma30.2AFP, KIT, CGA
5androgen insensitivity30.1SRY, CGA
6endodermal sinus tumor30.1INHA, AFP
7seminoma30.0CGA, KIT, AFP, INHA
8sertoli-leydig cell tumor29.9INHA, AFP
9choriocarcinoma29.9CGA, AFP, INHA
10leydig cell tumor29.8INHA, PTHLH, CGA
11wilms tumor29.6SRY, INHA
12germinoma29.5CGA, KIT, AFP, INHA
13adenocarcinoma29.3INHA, AFP, PTHLH
14down syndrome29.2INHA, AFP, SRY, CGA
15gonadal dysgenesis10.6
16hypercalcemia10.4
17swyer syndrome10.4
18testicular disease10.4SRY
19dysgerminoma of ovary10.4
20epithelioid trophoblastic tumor10.4INHA
21sertoli cell tumor10.4INHA
22pediatric ovarian dysgerminoma10.3
23ovarian gonadoblastoma10.3
24ataxia-telangiectasia10.3
25ataxia10.3
26oligohydramnios10.3AFP
27pineal dysgerminoma10.2
28hyperprolactinemia10.2PTHLH, CGA
29luteoma10.2CGA, SRY
30frasier syndrome10.2
31neuronitis10.2
32encephalitis10.2
33endometrial stromal sarcoma10.2INHA, KIT
34prolactinoma10.1CGA, PTHLH
35placental site trophoblastic tumor10.1INHA, CGA
36hypospadias10.1CGA, SRY
37trophoblastic neoplasm10.1CGA, INHA
38cryptorchidism10.1CGA, SRY
39male infertility10.1CGA, SRY
40islet cell tumor10.1AFP, PTHLH
41abrikosov's tumor10.1CGA, INHA
42gestational trophoblastic neoplasm10.1INHA, CGA
43leiomyosarcoma10.1KIT, INHA
44hematologic cancer10.1PTHLH, KIT
45klinefelter's syndrome10.1INHA, CGA
46neurilemmoma10.1INHA, KIT
47azoospermia10.1SRY, CGA
48testicular teratoma10.1AFP, CGA
49ovarian mixed germ cell neoplasm10.1AFP, CGA
50precocious puberty10.1

Graphical network of the top 20 diseases related to Dysgerminoma:



Diseases related to dysgerminoma

Symptoms for Dysgerminoma

About this section

Drugs & Therapeutics for Dysgerminoma

About this section

Drug clinical trials:

Search ClinicalTrials for Dysgerminoma

Search NIH Clinical Center for Dysgerminoma

Genetic Tests for Dysgerminoma

About this section

Anatomical Context for Dysgerminoma

About this section

MalaCards organs/tissues related to Dysgerminoma:

31
Ovary, Lymph node, Lung, Breast, Uterus, Brain, Pancreas, Thyroid, Skin, Placenta, Testes, Cervix, Myeloid, T cells

Animal Models for Dysgerminoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Dysgerminoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6KIT, AFP, INHA
2MP:00053767.5INHA, AFP, PTHLH, KIT, CGA
3MP:00107687.3INHA, AFP, PTHLH, SRY, KIT
4MP:00053797.2CGA, KIT, SRY, PTHLH, AFP, INHA
5MP:00053897.1INHA, AFP, PTHLH, SRY, KIT, CGA

Publications for Dysgerminoma

About this section

Articles related to Dysgerminoma:

(show top 50)    (show all 401)
idTitleAuthorsYear
1
Anti-Ma-associated encephalitis due to dysgerminoma in a woman with Swyer syndrome. (24711536)
2014
2
Microscopic dysgerminoma associated with anti-Ma2 paraneoplastic encephalitis in a patient with gonadal dysgenesis. (23518911)
2013
3
Bilateral poorly differentiated Sertoli-Leydig ovarian tumor associated with dysgerminoma: case report. (24601056)
2013
4
Ovarian dysgerminoma in an adolescent: a case report. (24377208)
2013
5
Novel mutation of the sex-determining region on the Y chromosome in a 46,XY female patient with monolateral dysgerminoma: a case report. (22889418)
2013
6
Ovarian Gonadoblastoma with Dysgerminoma in a Young Girl with 46, XX Karyotype: A Case Report. (24179931)
2013
7
Bilateral dysgerminoma in a patient with a previous diagnosis of Swyer syndrome. (22176344)
2012
8
Ovarian dysgerminoma in two sisters. (23012179)
2008
9
46 XY pure gonadal dysgenesis with gonadoblastoma and dysgerminoma. (19472738)
2008
10
Medical image. A prepubescent mass. Swyer syndrome with a bilateral dysgerminoma. (18392069)
2008
11
Chromosome 12p abnormalities in dysgerminoma of the ovary: a FISH analysis. (16554737)
2006
12
Gonadoblastoma with contralateral dysgerminoma in a young female--a case report. (16933739)
2006
13
Familial ovarian dysgerminomas (Swyer syndrome) in females associated with 46 XY-karyotype. (12012620)
2002
14
Dysgerminoma associated with hypercalcemia: A case report. (11431795)
2001
15
Pregnancy in a woman with a Y chromosome after removal of an ovarian dysgerminoma. (11104633)
2000
16
Advanced stage of dysgerminoma in testicular feminisation: is radical surgery necessary? (10925918)
2000
17
An unusual case of urinary incontinence, ataxia-telangiectasia, and metastatic dysgerminoma: case report and review of the literature. (9301718)
1997
18
Gonadoblastoma with dysgerminoma in one ovary and gonadoblastoma with dysgerminoma and yolk sac tumor in the contralateral ovary in a girl with 46XX karyotype. (7789879)
1995
19
Accumulation of gamma/delta T cells in human dysgerminoma and seminoma: roles in autologous tumor killing and granuloma formation. (7622197)
1995
20
Ovarian dysgerminoma: color Doppler ultrasonographic findings and comparison with CT and MR imaging findings. (8551550)
1995
21
The association of ovarian dysgerminoma and gonadoblastoma in a phenotypic female with 46 XY karyotype. (8005142)
1994
22
Gonadoblastoma and dysgerminoma associated with 46,XY pure gonadal dysgenesis--a case report. (8305146)
1993
23
Dysgerminoma of the ovary. An immunohistochemical study of tumor-infiltrating lymphoreticular cells and tumor cells. (8453580)
1993
24
Characterization of the inflammatory infiltrate in ovarian dysgerminoma: an immunocytochemical study. (1607150)
1992
25
Fine-needle aspiration biopsy of seminoma and dysgerminoma: cytologic, histologic, and electron microscopic correlations. (2159868)
1990
26
Dysgerminoma: a study of 13 cases from the Connecticut Tumor Registry. (2743762)
1989
27
Neuron-specific enolase as a serum marker for immature teratoma and dysgerminoma. (2910781)
1989
28
Experimental endocrinotherapy with tamoxifen of human ovarian dysgerminoma transplanted into nude mice. (3429992)
1987
29
Human chorionic gonadotrophin producing ovarian dysgerminoma. (3665890)
1987
30
Urinary retention secondary to ovarian dysgerminoma in a girl. (4012986)
1985
31
Pure dysgerminoma of the ovary with elevated serum human chorionic gonadotropin: diagnostic and therapeutic considerations. (2579008)
1985
32
Conservative treatment of ovarian dysgerminoma with subsequent pregnancy. (6704293)
1984
33
Dysgerminoma with syncytiotrophoblastic giant cells presenting as a hydatidiform mole. (6745734)
1984
34
Association of dermatomyositis and dysgerminoma in a 16-year-old patient. (6838683)
1983
35
Gonadoblastoma and dysgerminoma with ataxia-telangiectasia. (990441)
1976
36
Bilateral gonadoblastoma with dysgerminoma. A case report. (5057796)
1972
37
Essential hypernatremia, absence of thirst, hypopituitarism, and hypothalamic destruction due to a dysgerminoma. (4679411)
1972
38
Bilateral metachronous dysgerminoma with a 15-year interval. (5574081)
1971
39
Hormone studies of an ovarian dysgerminoma. (5129555)
1971
40
Ovarian dysgerminoma. A survey and 12 cases. (5658174)
1968
41
Late results of treatment of ovarian dysgerminoma in the material of the Institute of Oncology in the years 1947-1959. (6006207)
1966
42
DYSGERMINOMA OF THE OVARY: A CLINICAL REPORT OF 20 CASES. (14248209)
1964
43
A case of retroperitoneal metastasis of dysgerminoma ovarii. (14010609)
1962
44
Dysgerminoma ovarii. (13069746)
1953
45
Dysgerminoma treated with nitrogen mustard. (14894566)
1952
46
Ovarian dysgerminoma. (18864048)
1948
47
Fertility and dysgerminoma ovarii. (18877067)
1948
48
Dysgerminoma ovarii. (20247858)
1947
49
Dysgerminoma of the ovary. (20288041)
1947
50
A Case of Ovarian Dysgerminoma. (19992879)
1944

Variations for Dysgerminoma

About this section

Expression for genes affiliated with Dysgerminoma

About this section
Search GEO for disease gene expression data for Dysgerminoma.

Pathways for genes affiliated with Dysgerminoma

About this section

Pathways related to Dysgerminoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CGA, PTHLH
2
Show member pathways
9.3CGA, INHA
39.1CGA, AFP

Compounds for genes affiliated with Dysgerminoma

About this section

Compounds related to Dysgerminoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idCompoundScoreTop Affiliating Genes
1ag-12964410.0PTHLH, KIT
2clodronate44 50 1111.9PTHLH, CGA
3cloprostenol44 2810.7INHA, CGA
43beta-hydroxysteroid449.6CGA, INHA
5oestriol449.6AFP, CGA
6dbc-amp449.5PTHLH, CGA
7hematoxylin449.5INHA, KIT
8clomiphene citrate449.5AFP, CGA
9ifosfamide44 1110.5CGA, AFP
10ccl444 2810.4PTHLH, AFP
11diethylstilbestrol44 28 1111.4CGA, AFP
12dihydrotestosterone44 28 24 1112.4PTHLH, SRY, CGA
13agarose449.3INHA, SRY, KIT
14forskolin44 50 1111.3PTHLH, INHA, CGA
15cycloheximide449.2KIT, CGA, PTHLH
16vincristine44 50 1111.2KIT, AFP, PTHLH
17irinotecan44 50 1111.2AFP, KIT
18vinblastine44 50 1111.2CGA, AFP
19valine449.2AFP, PTHLH, KIT
20bleomycin44 1110.1CGA, PTHLH, AFP
21paclitaxel44 50 1111.1KIT, AFP, PTHLH
22glycogen44 2410.1PTHLH, KIT, AFP
23thyroxine44 2410.1CGA, PTHLH, AFP
24cyclophosphamide44 50 1111.1PTHLH, CGA, AFP
25cyclic amp44 2410.1INHA, CGA, PTHLH
26vitamin d449.1AFP, PTHLH, CGA
27thymidine44 2410.1KIT, AFP, PTHLH
28methotrexate50 44 1111.0KIT, CGA, AFP
29silver449.0SRY, AFP
30androstenedione44 2410.0CGA, INHA
31doxorubicin44 50 1111.0AFP, KIT, CGA
32cisplatin44 50 60 1112.0PTHLH, CGA, AFP
33creatinine449.0PTHLH, CGA, AFP
34heparin44 28 24 1111.9PTHLH, CGA, AFP
35hydrogen44 249.9AFP, INHA, PTHLH
36aspartate448.9AFP, KIT, CGA
37ribonucleic acid448.9INHA, CGA, PTHLH, KIT
38actinomycin d448.7AFP, PTHLH, KIT, CGA
39lactate448.7AFP, PTHLH, CGA, KIT
40vegf448.7CGA, KIT, PTHLH, AFP
41oligonucleotide448.4KIT, SRY, AFP, INHA
42serine448.2SRY, PTHLH, AFP, KIT, CGA
43paraffin448.1PTHLH, CGA, KIT, AFP, INHA
44progesterone44 28 60 24 1112.1KIT, INHA, AFP, PTHLH, CGA
45estrogen448.1INHA, AFP, KIT, CGA, PTHLH
46tyrosine448.1AFP, PTHLH, SRY, KIT, INHA
47estradiol44 24 1110.0INHA, AFP, CGA, SRY, PTHLH
48alanine448.0INHA, SRY, PTHLH, CGA, AFP
49testosterone44 60 24 1110.6PTHLH, SRY, KIT, CGA, INHA, AFP
50steroid447.6SRY, PTHLH, AFP, CGA, KIT, INHA

GO Terms for genes affiliated with Dysgerminoma

About this section

Biological processes related to Dysgerminoma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1erythrocyte differentiationGO:00302189.5KIT, INHA
2ovarian follicle developmentGO:00015419.5KIT, INHA
3positive regulation of cell migrationGO:00303359.5CGA, KIT
4male gonad developmentGO:00085849.4KIT, INHA
5regulation of cell proliferationGO:00421279.3KIT, INHA
6positive regulation of cell proliferationGO:00082849.2PTHLH, KIT, CGA
7skeletal system developmentGO:00015019.1PTHLH, INHA
8cell-cell signalingGO:00072679.1CGA, PTHLH, INHA

Molecular functions related to Dysgerminoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.9CGA, PTHLH, INHA

Sources for Dysgerminoma

About this section
2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet