MCID: DYS011
MIFTS: 24

Dyskinesia of Esophagus malady

Gastrointestinal diseases category

Summaries for Dyskinesia of Esophagus

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32MalaCards
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MalaCards: Dyskinesia of Esophagus, also known as esophageal motility disorders, is related to achalasia and esophagitis. An important gene associated with Dyskinesia of Esophagus is ATP4A (ATPase, H+/K+ exchanging, alpha polypeptide), and among its related pathways are SLC-mediated transmembrane transport and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds pantoprazole and Adenosine triphosphate have been mentioned in the context of this disorder.

Aliases & Classifications for Dyskinesia of Esophagus

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

dyskinesia of esophagus 8 10
esophageal motility disorders 44 60
esophageal motility disorder 8
oesophageal motor disorder 8
dyskinesia of oesophagus 8
oesophageal dysmotility 8
esophageal dysmotility 8


External Ids:

Disease Ontology8 DOID:9192
MeSH34 D015154
ICD9CM27 530.5
ICD1025 K22.4

Related Diseases for Dyskinesia of Esophagus

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dyskinesia of Esophagus:



Diseases related to dyskinesia of esophagus

Clinical Features for Dyskinesia of Esophagus

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Drugs & Therapeutics for Dyskinesia of Esophagus

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Dyskinesia of Esophagus

Drug clinical trials:

Search ClinicalTrials for Dyskinesia of Esophagus

Search NIH Clinical Center for Dyskinesia of Esophagus

Search CenterWatch for Dyskinesia of Esophagus

Genetic Tests for Dyskinesia of Esophagus

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Anatomical Context for Dyskinesia of Esophagus

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Animal Models for Dyskinesia of Esophagus or affiliated genes

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Publications for Dyskinesia of Esophagus

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Genetic Variations for Dyskinesia of Esophagus

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Expression for genes affiliated with Dyskinesia of Esophagus

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyskinesia of Esophagus

Search GEO for disease gene expression data for Dyskinesia of Esophagus.

Pathways for genes affiliated with Dyskinesia of Esophagus

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53Reactome, 29KEGG
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Pathways related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1ATP4A, ATP12A
2
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9.1ATP4A, ATP12A
3
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9.1ATP4A, ATP12A

Compounds for genes affiliated with Dyskinesia of Esophagus

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 28IUPHAR
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Compounds related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pantoprazole44 49 11 2412.1ATP4A, ATP12A
2Adenosine triphosphate11 2410.1ATP4A, ATP12A
3potassium44 11 2411.0ATP4A, ATP12A
4adp44 28 2410.8ATP4A, ATP12A

GO Terms for genes affiliated with Dyskinesia of Esophagus

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Sources:
16Gene Ontology
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Biological processes related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transmembrane transportGO:0550859.1ATP4A, ATP12A
2ATP biosynthetic processGO:0067549.0ATP4A, ATP12A
3ion transmembrane transportGO:0342208.8ATP4A, ATP12A

Molecular functions related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hydrogen:potassium-exchanging ATPase activityGO:0089009.1ATP4A, ATP12A

Products for genes affiliated with Dyskinesia of Esophagus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dyskinesia of Esophagus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet