MCID: DYS011
MIFTS: 27

Dyskinesia of Esophagus malady

Gastrointestinal diseases category

Summaries for Dyskinesia of Esophagus

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34MalaCards
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MalaCards: Dyskinesia of Esophagus, also known as esophageal motility disorders, is related to esophagitis and achalasia. An important gene associated with Dyskinesia of Esophagus is ATP4A (ATPase, H+/K+ exchanging, alpha polypeptide), and among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds pantoprazole and Phosphate have been mentioned in the context of this disorder. Related mouse phenotype digestive/alimentary.

Aliases & Classifications for Dyskinesia of Esophagus

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

dyskinesia of esophagus 9 11
esophageal motility disorders 46 63
esophageal motility disorder 9
oesophageal motor disorder 9
dyskinesia of oesophagus 9
oesophageal dysmotility 9
esophageal dysmotility 9


External Ids:

Disease Ontology9 DOID:9192
ICD9CM28 530.5
MeSH36 D015154
ICD1026 K22.4

Related Diseases for Dyskinesia of Esophagus

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Dyskinesia of Esophagus:



Diseases related to dyskinesia of esophagus

Symptoms for Dyskinesia of Esophagus

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Drugs & Therapeutics for Dyskinesia of Esophagus

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Dyskinesia of Esophagus

Drug clinical trials:

Search ClinicalTrials for Dyskinesia of Esophagus

Search NIH Clinical Center for Dyskinesia of Esophagus

Search CenterWatch for Dyskinesia of Esophagus

Genetic Tests for Dyskinesia of Esophagus

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Anatomical Context for Dyskinesia of Esophagus

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Animal Models for Dyskinesia of Esophagus or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Dyskinesia of Esophagus:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.1ATP12A, ATP4A

Publications for Dyskinesia of Esophagus

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Variations for Dyskinesia of Esophagus

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Expression for genes affiliated with Dyskinesia of Esophagus

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyskinesia of Esophagus

Search GEO for disease gene expression data for Dyskinesia of Esophagus.

Pathways for genes affiliated with Dyskinesia of Esophagus

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Sources:
51PathCards, 56Reactome, 31KEGG, 39NCBI BioSystems Database
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Pathways related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1ATP12A, ATP4A
2
Show member pathways
9.1ATP12A, ATP4A
3
Show member pathways
9.1ATP12A, ATP4A
4
Show member pathways
calcium transport I39
9.1ATP12A, ATP4A

Compounds for genes affiliated with Dyskinesia of Esophagus

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Sources:
46Novoseek, 52PharmGKB, 25HMDB, 12DrugBank, 30IUPHAR
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Compounds related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pantoprazole46 52 25 1212.2ATP12A, ATP4A
2Phosphate259.2ATP12A, ATP4A
3potassium46 25 1211.1ATP12A, ATP4A
4Adenosine triphosphate25 1210.1ATP12A, ATP4A
5Water259.0ATP4A, ATP12A
6adp46 30 2510.8ATP12A, ATP4A

GO Terms for genes affiliated with Dyskinesia of Esophagus

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Sources:
17Gene Ontology
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Biological processes related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transmembrane transportGO:0550859.1ATP12A, ATP4A
2ATP biosynthetic processGO:0067549.0ATP12A, ATP4A
3ion transmembrane transportGO:0342208.8ATP12A, ATP4A

Molecular functions related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hydrogen:potassium-exchanging ATPase activityGO:0089009.1ATP12A, ATP4A

Products for genes affiliated with Dyskinesia of Esophagus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dyskinesia of Esophagus

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet