MCID: DYS011
MIFTS: 23

Dyskinesia of Esophagus malady

Gastrointestinal category

Summaries for Dyskinesia of Esophagus

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Dyskinesia of Esophagus, also known as esophageal motility disorders, is related to achalasia and eosinophilic esophagitis. An important gene associated with Dyskinesia of Esophagus is ATP4A (ATPase, H+/K+ exchanging, alpha polypeptide), and among its related pathways are SLC-mediated transmembrane transport and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds pantoprazole and Adenosine triphosphate have been mentioned in the context of this disorder.

Aliases & Classifications for Dyskinesia of Esophagus

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH, 27ICD9CM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal


Aliases & Descriptions:

dyskinesia of esophagus 8 10
esophageal motility disorders 45 61
esophageal motility disorder 8
oesophageal motor disorder 8
dyskinesia of oesophagus 8
oesophageal dysmotility 8
esophageal dysmotility 8


External Ids:

Disease Ontology8 DOID:9192
MeSH35 D015154
ICD9CM27 530.5
ICD1025 K22.4

Related Diseases for Dyskinesia of Esophagus

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Dyskinesia of Esophagus:



Diseases related to dyskinesia of esophagus

Clinical Features for Dyskinesia of Esophagus

Drugs & Therapeutics for Dyskinesia of Esophagus

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Dyskinesia of Esophagus

Drug clinical trials:

Search ClinicalTrials for Dyskinesia of Esophagus

Search NIH Clinical Center for Dyskinesia of Esophagus

Search CenterWatch for Dyskinesia of Esophagus

Genetic Tests for Dyskinesia of Esophagus

Anatomical Context for Dyskinesia of Esophagus

Animal Models for Dyskinesia of Esophagus or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Dyskinesia of Esophagus

Genetic Variations for Dyskinesia of Esophagus

Expression for genes affiliated with Dyskinesia of Esophagus

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Dyskinesia of Esophagus

Search GEO for disease gene expression data for Dyskinesia of Esophagus.

Pathways for genes affiliated with Dyskinesia of Esophagus

Sources:
54Reactome, 30KEGG
See all sources

Pathways related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1ATP4A, ATP12A
2
Hide members
9.1ATP4A, ATP12A
3
Hide members
9.1ATP4A, ATP12A

Compounds for genes affiliated with Dyskinesia of Esophagus

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 24HMDB, 29IUPHAR
See all sources

Compounds related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pantoprazole45 50 11 2412.1ATP4A, ATP12A
2Adenosine triphosphate11 2410.1ATP4A, ATP12A
3potassium45 11 2411.0ATP4A, ATP12A
4adp45 29 2410.8ATP4A, ATP12A

GO Terms for genes affiliated with Dyskinesia of Esophagus

Sources:
16Gene Ontology
See all sources

Biological processes related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transmembrane transportGO:0550859.1ATP4A, ATP12A
2ATP biosynthetic processGO:0067549.0ATP4A, ATP12A
3ion transmembrane transportGO:0342208.8ATP4A, ATP12A

Molecular functions related to Dyskinesia of Esophagus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hydrogen:potassium-exchanging ATPase activityGO:0089009.1ATP4A, ATP12A

Products for genes affiliated with Dyskinesia of Esophagus

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dyskinesia of Esophagus

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet