MCID: DYS005
MIFTS: 36

Dyslexia malady

Summaries for Dyslexia

Sources:
8Disease Ontology, 44NINDS, 64Wikipedia, 33MalaCards
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NINDS:44 Dyslexia is a brain-based type of learning disability that specifically impairs a person's ability to read. These individuals typically read at levels significantly lower than expected despite having normal intelligence. Although the disorder varies from person to person, common characteristics among people with dyslexia are difficulty with phonological processing (the manipulation of sounds), spelling, and/or rapid visual-verbal responding. In individuals with adult onset of dyslexia, it usually occurs as a result of brain injury or in the context of dementia; this contrasts with individuals with dyslexia who simply were never identified as children or adolescents.

MalaCards: Dyslexia is related to dyslexia 2 and dysgraphia. An important gene associated with Dyslexia is DYX1C1 (dyslexia susceptibility 1 candidate 1). Affiliated tissues include whole blood, brain and cortex.

Disease Ontology:8 A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.

Wikipedia:64 Dyslexia is characterized by difficulty with learning to read fluently and with accurate comprehension... more...

Aliases & Classifications for Dyslexia

Sources:
8Disease Ontology, 44NINDS, 10DISEASES, 61UMLS, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

dyslexia 8 44 10 61


External Ids:

Disease Ontology8 DOID:4428
MeSH35 D004410

Related Diseases for Dyslexia

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dyslexia:



Diseases related to dyslexia

Clinical Features for Dyslexia

Drugs & Therapeutics for Dyslexia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Dyslexia

Search CenterWatch for Dyslexia

Genetic Tests for Dyslexia

Anatomical Context for Dyslexia

Sources:
33MalaCards
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MalaCards organs/tissues related to Dyslexia:

33
Whole blood, Brain, Cortex, Cerebellum, Breast, Prefrontal cortex, Thalamus

Animal Models for Dyslexia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Dyslexia

Sources:
51PubMed
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Articles related to Dyslexia:

(show top 50)    (show all 585)
idTitleAuthorsYear
1
An investigation into the origin of anatomical differences in dyslexia. (24431448)
2014
2
Left hemiparalexia of Chinese characters: neglect dyslexia or disruption of pathway of visual word form processing? (23299955)
2014
3
Project DyAdd: Implicit learning in adult dyslexia and ADHD. (24162872)
2013
4
Non-adjacent dependency learning in infants at familial risk of dyslexia. (23217289)
2013
5
Diagnostic profiles of children with developmental dyslexia in a transparent orthography. (24076984)
2013
6
Abnormal visual motion processing is not a cause of dyslexia. (23746630)
2013
7
Dissociation in Optokinetic Stimulation Sensitivity between Omission and Substitution Reading Errors in Neglect Dyslexia. (24062678)
2013
8
Do students with dyslexia have a different personality profile as measured with the big five? (23691229)
2013
9
Transcranial direct current stimulation: a remediation tool for the treatment of childhood congenital dyslexia? (23626530)
2013
10
Gray and white matter distribution in dyslexia: a VBM study of superior temporal gyrus asymmetry. (24098565)
2013
11
Intact but less accessible phonetic representations in adults with dyslexia. (24311693)
2013
12
Saccadic alterations in severe developmental dyslexia. (23819080)
2013
13
Understanding the mental lexicon through neglect dyslexia: a study on compound noun reading. (22519604)
2013
14
A tractography study in dyslexia: neuroanatomic correlates of orthographic, phonological and speech processing. (22327793)
2012
15
A comparison of phonological processing skills of children with mild to moderate sensorineural hearing loss and children with dyslexia. (22978204)
2012
16
Dissociation between online and offline learning in developmental dyslexia. (22221291)
2012
17
Evidence for a deficit in orthographic structure processing in Chinese developmental dyslexia: an event-related potential study. (22750287)
2012
18
An interaction-dominant perspective on reading fluency and dyslexia. (22460607)
2012
19
Neural evidence of allophonic perception in children at risk for dyslexia. (22569214)
2012
20
Progressive dyslexia: evidence from Hungarian and English. (22713383)
2012
21
Sound can improve visual search in developmental dyslexia. (22064932)
2012
22
Dissociation between the procedural learning of letter names and motor sequences in developmental dyslexia. (22750119)
2012
23
Rise time and formant transition duration in the discrimination of speech sounds: the Ba-Wa distinction in developmental dyslexia. (21159086)
2011
24
The cost-effectiveness of an intensive treatment protocol for severe dyslexia in children. (21793122)
2011
25
The effects of embryonic knockdown of the candidate dyslexia susceptibility gene homologue Dyx1c1 on the distribution of GABAergic neurons in the cerebral cortex. (21070838)
2011
26
Is developmental dyslexia modality specific? A visual-auditory comparison of Italian dyslexics. (21382386)
2011
27
Visual temporal processing in dyslexia and the magnocellular deficit theory: the need for speed? (21823808)
2011
28
Altered low-I^ sampling in auditory cortex accounts for the three main facets of dyslexia. (22196341)
2011
29
Electrophysiological evidence for impaired attentional engagement with phonologically acceptable misspellings in developmental dyslexia. (21734903)
2011
30
Dyslexia and practice in the attentional blink: evidence of slower task learning in dyslexia. (20409539)
2011
31
Dyslexia. (21240117)
2011
32
Reading compounds in neglect dyslexia: the headedness effect. (21810435)
2011
33
Psychosocial experiences associated with confirmed and self-identified dyslexia: a participant-driven concept map of adult perspectives. (20574060)
2011
34
Behavioral performances in participants with phonological dyslexia and different patterns on the N170 component. (21094575)
2011
35
Pleiotropic effects of DCDC2 and DYX1C1 genes on language and mathematics traits in nuclear families of developmental dyslexia. (21046216)
2011
36
Learning disabilities, dyslexia, and vision: The role of the pediatric ophthalmologist. (21596289)
2011
37
Nursing success in the face of dyslexia. (21488543)
2011
38
Hearing abilities in children with dyslexia and attention deficit hyperactivity disorder. (20339804)
2010
39
Identification of candidate genes for dyslexia susceptibility on chromosome 18. (21060895)
2010
40
Teacher attitudes toward dyslexia: effects on teacher expectations and the academic achievement of students with dyslexia. (20445201)
2010
41
A common variant associated with dyslexia reduces expression of the KIAA0319 gene. (19325871)
2009
42
A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia. (17309879)
2007
43
Patterns of developmental dyscalculia with or without dyslexia. (17999343)
2007
44
No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia. (15477871)
2005
45
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. (15717286)
2005
46
A dominant gene for developmental dyslexia on chromosome 3. (11584043)
2001
47
Dyslexia: oral and written language disorder. A new look at old links. (10473999)
2000
48
Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15. (10638372)
1999
49
Urine patterns, peptide levels and IgA/IgG antibodies to food proteins in children with dyslexia. (9689235)
1997
50
Anosognosia for hemiplegia, neglect dyslexia, and drawing neglect: clinical findings and theoretical considerations. (9375168)
1996

Genetic Variations for Dyslexia

Expression for genes affiliated with Dyslexia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyslexia

Search GEO for disease gene expression data for Dyslexia.

Pathways for genes affiliated with Dyslexia

Compounds for genes affiliated with Dyslexia

GO Terms for genes affiliated with Dyslexia

Sources:
16Gene Ontology
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Biological processes related to Dyslexia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:00176410.3KIAA0319, DCDC2, DYX1C1

Products for genes affiliated with Dyslexia

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Sources for Dyslexia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet