MCID: DYS005
MIFTS: 36

Dyslexia malady

Summaries for Dyslexia

About this section
Sources:
8Disease Ontology, 43NINDS, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NINDS:43 Dyslexia is a brain-based type of learning disability that specifically impairs a person's ability to read. These individuals typically read at levels significantly lower than expected despite having normal intelligence. Although the disorder varies from person to person, common characteristics among people with dyslexia are difficulty with phonological processing (the manipulation of sounds), spelling, and/or rapid visual-verbal responding. In individuals with adult onset of dyslexia, it usually occurs as a result of brain injury or in the context of dementia; this contrasts with individuals with dyslexia who simply were never identified as children or adolescents.

MalaCards: Dyslexia is related to dyslexia 2 and dysgraphia. An important gene associated with Dyslexia is DYX1C1 (dyslexia susceptibility 1 candidate 1). Affiliated tissues include brain, testes and eye.

Disease Ontology:8 A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.

Wikipedia:63 Dyslexia, or developmental reading disorder, is characterized by difficulty with learning to read... more...

Aliases & Classifications for Dyslexia

About this section
Sources:
8Disease Ontology, 43NINDS, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
See all sources

Aliases & Descriptions:

dyslexia 8 43 10 60


External Ids:

Disease Ontology8 DOID:4428
MeSH34 D004410

Related Diseases for Dyslexia

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Dyslexia:



Diseases related to dyslexia

Clinical Features for Dyslexia

About this section

Drugs & Therapeutics for Dyslexia

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Dyslexia

Drug clinical trials:

Search ClinicalTrials for Dyslexia

Search NIH Clinical Center for Dyslexia

Search CenterWatch for Dyslexia

Genetic Tests for Dyslexia

About this section

Anatomical Context for Dyslexia

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Dyslexia:

32
Brain, Testes, Eye, Cortex, Cerebellum, Breast, Thalamus

Animal Models for Dyslexia or affiliated genes

About this section

Publications for Dyslexia

About this section
Sources:
50PubMed
See all sources

Articles related to Dyslexia:

(show top 50)    (show all 585)
idTitleAuthorsYear
1
Auditory processing in children with dyslexia: electrophysiological and behavior evaluation. (24408169)
2013
2
Predictors of developmental dyslexia in European orthographies with varying complexity. (23227813)
2013
3
Mathematical difficulties in nonverbal learning disability or co-morbid dyscalculia and dyslexia. (23971493)
2013
4
I can read it in your eyes: what eye movements tell us about visuo-attentional processes in developmental dyslexia. (23041659)
2013
5
Social priming of dyslexia and reduction of the Stroop effect: What component of the Stroop effect is actually reduced? (24387881)
2013
6
Impaired auditory sampling in dyslexia: further evidence from combined fMRI and EEG. (23950742)
2013
7
Syntactic comprehension in reading and listening: a study with French children with dyslexia. (22711663)
2013
8
Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial. (24206099)
2013
9
Enhanced recognition memory after incidental encoding in children with developmental dyslexia. (23717524)
2013
10
A lab-controlled simulation of a letter-speech sound binding deficit in dyslexia. (23708733)
2013
11
Brain hemisphericity and developmental dyslexia. (23475004)
2013
12
Cognitive subtypes of dyslexia are characterized by distinct patterns of grey matter volume. (23775490)
2013
13
Is the impaired N170 print tuning specific to developmental dyslexia? A matched reading-level study with poor readers and dyslexics. (24148146)
2013
14
Position of neocortical neurons transfected at different gestational ages with shRNA targeted against candidate dyslexia susceptibility genes. (23724130)
2013
15
Dense-map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36. (23190410)
2013
16
Reduced phase locking to slow amplitude modulation in adults with dyslexia: an MEG study. (22001790)
2012
17
Dyslexia, authorial identity, and approaches to learning and writing: a mixed methods study. (22583092)
2012
18
Genetic variant in KIAA0319, but not in DYX1C1, is associated with risk of dyslexia: an integrated meta-analysis. (23065966)
2012
19
Validity of a protocol for adult self-report of dyslexia and related difficulties. (22271419)
2012
20
The multiple-lemma representation of Italian compound nouns: a single case study of deep dyslexia. (22300880)
2012
21
When 'slime' becomes 'smile': developmental letter position dyslexia in English. (22820637)
2012
22
Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure. (22683091)
2012
23
The Influence of Pathologies upon Sensory Perception and Sensory Coordination in Children with Developmental Dyslexia and Learning Disorders: A Unified Theory of Developmental Dyslexia. (22454821)
2012
24
Progressive aphasia presenting with deep dyslexia and dysgraphia. (22465163)
2012
25
The development of print tuning in children with dyslexia: evidence from longitudinal ERP data supported by fMRI. (21040695)
2011
26
How many functional brains in developmental dyslexia? When the history of language delay makes the difference. (21697712)
2011
27
Specifying theories of developmental dyslexia: a diffusion model analysis of word recognition. (22010894)
2011
28
The effect of syntax on reading in neglect dyslexia. (21679719)
2011
29
Slow perceptual processing at the core of developmental dyslexia: a parameter-based assessment of visual attention. (21903119)
2011
30
Rate- and accuracy-disabled subtype profiles among adults with dyslexia in the Hebrew orthography. (21978011)
2011
31
Evidence for a specific cross-modal association deficit in dyslexia: an electrophysiological study of letter-speech sound processing. (21676085)
2011
32
Do reading processes differ in transparent versus opaque orthographies? A study of acquired dyslexia in Welsh/English bilinguals. (22813069)
2011
33
Reduced attentional capacity, but normal processing speed and shifting of attention in developmental dyslexia: evidence from a serial task. (20655514)
2011
34
Lexical tone awareness among Chinese children with developmental dyslexia. (21092370)
2011
35
Another joint statement regarding learning disabilities, dyslexia, and vision--a rebuttal. (20728412)
2010
36
Temporal order judgment in dyslexia--task difficulty or temporal processing deficiency? (20412813)
2010
37
Coherence motion perception in developmental dyslexia: a meta-analysis of behavioral studies. (20957687)
2010
38
Is the 'naming' deficit in dyslexia a misnomer? (20413113)
2010
39
Neglect dyslexia: a review of the neuropsychological literature. (20714712)
2010
40
Rats, dyslexia, and the magnocellular system. (20138264)
2010
41
A test of the cerebellar hypothesis of dyslexia in adequate and inadequate responders to reading intervention. (20298639)
2010
42
Sentence comprehension in young adults with developmental dyslexia. (19911285)
2009
43
No evidence for association between dyslexia and DYX1C1 functional variants in a group of children and adolescents from Southern Italy. (16280601)
2005
44
Putative functional alleles of DYX1C1 are not associated with dyslexia susceptibility in a large sample of sibling pairs from the UK. (15520411)
2004
45
Maternal antibody-mediated dyslexia? Evidence for a pathogenic serum factor in a mother of two dyslexic children shown by transfer to mice using behavioural studies and magnetic resonance spectroscopy. (12225907)
2002
46
Dyslexia Dysorthography Dyscalculia: Review of the scientific data (21348173)
2000
47
Phonological dyslexia and phonological dysgraphia following left and right hemispherectomy. (8822737)
1996
48
Developmental surface dyslexia and dysgraphia: an orthographic processing impairment. (1565802)
1992
49
Defining dyslexia as a developmental language disorder. (24233471)
1989
50
DEVELOPMENTAL APHASIA: Also known as Congenital Word-blindness and sometimes referred to as Alexia or Dyslexia. (18170488)
1948

Genetic Variations for Dyslexia

About this section

Expression for genes affiliated with Dyslexia

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Dyslexia

Search GEO for disease gene expression data for Dyslexia.

Pathways for genes affiliated with Dyslexia

About this section

Compounds for genes affiliated with Dyslexia

About this section

GO Terms for genes affiliated with Dyslexia

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Dyslexia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:00176410.3KIAA0319, DCDC2, DYX1C1

Products for genes affiliated with Dyslexia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dyslexia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet