MCID: DYS005
MIFTS: 36

Dyslexia malady

Summaries for Dyslexia

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Sources:
8Disease Ontology, 43NINDS, 63Wikipedia, 32MalaCards
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NINDS:43 Dyslexia is a brain-based type of learning disability that specifically impairs a person's ability to read. These individuals typically read at levels significantly lower than expected despite having normal intelligence. Although the disorder varies from person to person, common characteristics among people with dyslexia are difficulty with phonological processing (the manipulation of sounds), spelling, and/or rapid visual-verbal responding. In individuals with adult onset of dyslexia, it usually occurs as a result of brain injury or in the context of dementia; this contrasts with individuals with dyslexia who simply were never identified as children or adolescents.

MalaCards: Dyslexia is related to dyslexia 2 and dysgraphia. An important gene associated with Dyslexia is DYX1C1 (dyslexia susceptibility 1 candidate 1). Affiliated tissues include brain, testes and eye.

Disease Ontology:8 A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.

Wikipedia:63 Dyslexia, or developmental reading disorder, is characterized by difficulty with learning to read... more...

Aliases & Classifications for Dyslexia

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Sources:
8Disease Ontology, 43NINDS, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

dyslexia 8 43 10 60


External Ids:

Disease Ontology8 DOID:4428
MeSH34 D004410

Related Diseases for Dyslexia

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dyslexia:



Diseases related to dyslexia

Clinical Features for Dyslexia

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Drugs & Therapeutics for Dyslexia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Dyslexia

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Genetic Tests for Dyslexia

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Anatomical Context for Dyslexia

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Sources:
32MalaCards
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MalaCards organs/tissues related to Dyslexia:

32
Brain, Testes, Eye, Cerebellum, Cortex, Breast, Thalamus

Animal Models for Dyslexia or affiliated genes

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Publications for Dyslexia

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Sources:
50PubMed
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Articles related to Dyslexia:

(show top 50)    (show all 585)
idTitleAuthorsYear
1
Neuronal correlates of mental rotation performance in children with developmental dyslexia. (24089017)
2014
2
Evidence for cerebellar dysfunction in Chinese children with developmental dyslexia: an fMRI study. (23227882)
2013
3
Implicit sequence learning in dyslexia: a within-sequence comparison of first- and higher-order information. (22996058)
2013
4
Characterizing the morphosyntactic processing deficit and its relationship to phonology in developmental dyslexia. (23628368)
2013
5
The effect of different stimulus attributes on the attentional performance of children with attention deficit/hyperactivity disorder and dyslexia. (24029807)
2013
6
Sight Word and Phonics Training in Children With Dyslexia. (24085229)
2013
7
The role of morphology in reading in Spanish-speaking children with dyslexia. (23866248)
2013
8
Preschool language profiles of children at family risk of dyslexia: continuities with specific language impairment. (23772651)
2013
9
An assessment of gene-by-environment interactions in developmental dyslexia-related phenotypes. (23176554)
2013
10
Altered Neuronal Response During Rapid Auditory Processing and Its Relation to Phonological Processing in Prereading Children at Familial Risk for Dyslexia. (23599167)
2013
11
A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults. (23423138)
2013
12
IQ of Four-Year-Olds Who Go On to Develop Dyslexia. (23492905)
2013
13
Dyslexia. (23622168)
2013
14
Neural evidence of the allophonic mode of speech perception in adults with dyslexia. (23403261)
2013
15
Eye-movement study during visual search in Chinese children with developmental dyslexia. (24238519)
2013
16
Impaired short-term memory for order in adults with dyslexia. (23644228)
2013
17
A teacher with progressive headache, dyslexia, dysgraphia and seizure. (24250931)
2013
18
Analysis of genetic variants of dyslexia candidate genes KIAA0319 and DCDC2 in Indian population. (23677054)
2013
19
Basic auditory processing deficits in dyslexia: systematic review of the behavioral and event-related potential/ field evidence. (22323280)
2013
20
Line bisection error predicts the presence and severity of neglect dyslexia in paragraph reading. (23142349)
2013
21
Molecular genetics of dyslexia: an overview. (24133036)
2013
22
Subtypes of developmental dyslexia: testing the predictions of the dual-route and connectionist frameworks. (23010562)
2013
23
Intervention for a multi-character processing deficit in a Greek-speaking child with surface dyslexia. (24107243)
2013
24
Past-tense morphology and phonological deficits in children with dyslexia and children with language impairment. (22714029)
2013
25
Lack of association between genetic polymorphisms in ROBO1, MRPL19/C2ORF3 and THEM2 with developmental dyslexia. (23954868)
2013
26
Why do adults with dyslexia have poor global motion sensitivity? (24376414)
2013
27
Family-based genome-wide copy number scan identifies five new genes of dyslexia involved in dendritic spinal plasticity. (23677055)
2013
28
Low-level deficits in beat perception: neither necessary nor sufficient for explaining developmental dyslexia in a consistent orthography. (22695074)
2012
29
Spherical harmonic analysis of cortical complexity in autism and dyslexia. (22545198)
2012
30
Is "hit and run" a single word? The processing of irreversible binomials in neglect dyslexia. (22347199)
2012
31
Sensitivity to lexical stress in dyslexia: a case of cognitive not perceptual stress. (22589197)
2012
32
Acquired dyslexia in three writing systems: study of a Portuguese-Japanese bilingual aphasic patient. (22713387)
2012
33
Allophonic mode of speech perception in Dutch children at risk for dyslexia: a longitudinal study. (22522205)
2012
34
DCDC2 genetic variants and susceptibility to developmental dyslexia. (21881542)
2012
35
Abrupt and ramped flicker-defined form shows evidence for a large magnocellular impairment in dyslexia. (22609580)
2012
36
Neural dissociation of phonological and visual attention span disorders in developmental dyslexia: FMRI evidence from two case reports. (22285025)
2012
37
Acquired dyslexia and dysgraphia across scripts. (22713382)
2012
38
Reading for sound with dyslexia: evidence for early orthographic and late phonological integration deficits. (21316349)
2011
39
Early predictors of dyslexia in Chinese children: familial history of dyslexia, language delay, and cognitive profiles. (20735514)
2011
40
Cognitive-linguistic performances of multilingual university students suspected of dyslexia. (21500321)
2011
41
Spelling deficits in dyslexia: evaluation of an orthographic spelling training. (20352378)
2010
42
Visual spatial attention and speech segmentation are both impaired in preschoolers at familial risk for developmental dyslexia. (20680993)
2010
43
Abnormal pattern of cortical speech feature discrimination in 6-year-old children at risk for dyslexia. (20381471)
2010
44
Computer-assisted instruction to prevent early reading difficulties in students at risk for dyslexia: Outcomes from two instructional approaches. (20052566)
2010
45
Implicit phonological and semantic processing in children with developmental dyslexia: evidence from event-related potentials. (20430041)
2010
46
Do deep dyslexia, dysphasia and dysgraphia share a common phonological impairment? (17227679)
2007
47
Patterns of peripheral paralexia: pure alexia and the forgotten visual dyslexia? (17131595)
2006
48
Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia. (17033633)
2006
49
No evidence for association and linkage disequilibrium between dyslexia and markers of four dopamine-related genes. (14505070)
2003
50
Dissociation between reading and written spelling in two Italian children: dyslexia without dysgraphia? (4058715)
1985

Genetic Variations for Dyslexia

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Expression for genes affiliated with Dyslexia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dyslexia

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Pathways for genes affiliated with Dyslexia

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Compounds for genes affiliated with Dyslexia

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GO Terms for genes affiliated with Dyslexia

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Sources:
16Gene Ontology
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Biological processes related to Dyslexia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:00176410.3KIAA0319, DCDC2, DYX1C1

Products for genes affiliated with Dyslexia

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Sources for Dyslexia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet