MCID: DYS009
MIFTS: 37

Dysthymic Disorder malady

Categories: Mental diseases

Aliases & Classifications for Dysthymic Disorder

Aliases & Descriptions for Dysthymic Disorder:

Name: Dysthymic Disorder 12 42 14 69
Dysthymia 12 52

Classifications:



External Ids:

Disease Ontology 12 DOID:12139
ICD10 33 F34.1
ICD9CM 35 300.4
MeSH 42 D019263
NCIt 47 C34562
SNOMED-CT 64 192384008 78667006
UMLS 69 C0013415

Summaries for Dysthymic Disorder

Disease Ontology : 12 A mood disorder that involves the presence of a low mood almost daily over a span of at least two years.

MalaCards based summary : Dysthymic Disorder, also known as dysthymia, is related to personality disorder and antisocial personality disorder. An important gene associated with Dysthymic Disorder is HTR2A (5-Hydroxytryptamine Receptor 2A), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Serotonergic synapse. The drugs Methyltestosterone and Testosterone have been mentioned in the context of this disorder. Affiliated tissues include brain.

Wikipedia : 71 Dysthymia, also known as persistent depressive disorder (PDD), is a mood disorder consisting of the same... more...

Related Diseases for Dysthymic Disorder

Diseases related to Dysthymic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
id Related Disease Score Top Affiliating Genes
1 personality disorder 30.0 HTR2A HTR7 MAOA SLC6A4
2 antisocial personality disorder 10.2 HTR2A PIR
3 indeterminate leprosy 10.2 HTR2A HTR7
4 anxiety disorder 10.1
5 nephronophthisis 13 10.1 HTR2A SLC6A4
6 splenic abscess 10.1 HTR2A SLC6A4
7 allergic hypersensitivity disease 10.1 HTR2A HTR7
8 euthyroid sick syndrome 10.1 HTR2A SLC6A4
9 vascular cancer 10.1 HTR2A HTR7
10 ornithosis 10.1 MAOA SLC6A4
11 waardenburg's syndrome 10.1 HTR2A SLC6A4
12 colorectal adenocarcinoma 10.1 MAOA SLC6A4
13 attention deficit-hyperactivity disorder 10.1
14 schizoid personality disorder 10.1 PIR SLC6A4
15 strongyloidiasis 10.1 MAOA SLC6A4
16 chronic eosinophilic pneumonia 10.1 MAOA SLC6A4
17 pyromania 10.0 HTR2A MAOA SLC6A4
18 intrahepatic gall duct cancer 10.0 HTR2A MAOA SLC6A4
19 hypoglycemic coma 10.0 HTR2A MAOA SLC6A4
20 multiple personality disorder 10.0 HTR2A MAOA SLC6A4
21 cytomegalic congenital adrenal hypoplasia 10.0 HTR2A MAOA SLC6A4
22 hepatitis b reinfection following liver transplantation 10.0 HTR2A MAOA SLC6A4
23 postencephalitic parkinson disease 10.0 HTR2A MAOA SLC6A4
24 cecal benign neoplasm 10.0 HTR2A MAOA SLC6A4
25 hematocele of tunica vaginalis testis 10.0 HTR7 SLC6A4
26 hereditary multiple exostoses 10.0 HTR2A MAOA SLC6A4
27 lichen disease 10.0 HTR2A MAOA SLC6A4
28 fechtner syndrome 10.0 HTR2A MAOA SLC6A4
29 mastitis 10.0 HTR7 PIR
30 hepatitis d 10.0 HTR2A MAOA SLC6A4
31 retinoblastoma 10.0 HTR2A MAOA SLC6A4
32 benign epilepsy with centrotemporal spikes 10.0 HTR2A MAOA SLC6A4
33 deafness, autosomal recessive 20 10.0 HTR7 SLC6A4
34 adult brainstem astrocytoma 10.0 MAOA PIR SLC6A4
35 primary angle-closure glaucoma 10.0 HTR2A SLC6A4
36 kidney pelvis papillary carcinoma 10.0 MAOA PIR SLC6A4
37 atrial fibrillation, familial, 10 10.0 HTR2A MAOA SLC6A4
38 carotid stenosis 10.0 MAOA SLC6A4
39 generalized anxiety disorder 10.0
40 dry eye syndrome 10.0 HTR2A HTR7 SLC6A4
41 luxation of globe 10.0 HTR7 SLC6A4
42 renpenning syndrome 10.0 HTR7 MAOA SLC6A4
43 bartter disease 9.9 HTR2A HTR7 SLC6A4
44 ellis-van creveld syndrome 9.9 HTR2A MAOA SLC6A4
45 obsessive-compulsive disorder 9.9
46 tuberculous peritonitis 9.9 HTR7 SLC6A4
47 microcephaly 13, primary, autosomal recessive 9.8 HTR2A HTR7 MAOA SLC6A4
48 alzheimer disease 17 9.8 GATA3 HTR2A HTR7 SLC6A4
49 conjunctival pigmentation 9.8 GATA3 HTR7 MAOA SLC6A4
50 tinea pedis 9.8 GATA3 HTR7 MAOA SLC6A4

Comorbidity relations with Dysthymic Disorder via Phenotypic Disease Network (PDN): (show top 50) (show all 53)


Active Peptic Ulcer Disease Acute Cystitis
Adjustment Disorder Anxiety Disorder
Atrophic Gastritis Atypical Depressive Disorder
Avoidant Personality Disorder Benign Essential Hypertension
Borderline Personality Disorder Bronchitis
Chronic Myocardial Ischemia Chronic Pulmonary Heart Disease
Conversion Disorder Deficiency Anemia
Delusional Disorder Dependent Personality Disorder
Dyskinesia of Esophagus Esophagitis
Familial Atrial Fibrillation Generalized Anxiety Disorder
Generalized Atherosclerosis Heart Disease
Histrionic Personality Disorder Hypertension, Essential
Hypochondriasis Hypothyroidism
Intermediate Coronary Syndrome Iron Deficiency Anemia
Irritable Bowel Syndrome Ischemic Heart Disease
Mitral Valve Disease Mood Disorder
Narcissistic Personality Disorder Obsessive-Compulsive Disorder
Obsessive-Compulsive Personality Disorder Opiate Dependence
Oral Candidiasis Orthostatic Intolerance
Osteoarthritis Osteoporosis
Paralytic Ileus Parkinson Disease, Late-Onset
Peripheral Vascular Disease Personality Disorder
Post-Traumatic Stress Disorder Postinflammatory Pulmonary Fibrosis
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Social Phobia

Graphical network of the top 20 diseases related to Dysthymic Disorder:



Diseases related to Dysthymic Disorder

Symptoms & Phenotypes for Dysthymic Disorder

Drugs & Therapeutics for Dysthymic Disorder

Drugs for Dysthymic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyltestosterone Approved Phase 4 58-18-4 6010
2
Testosterone Approved, Investigational Phase 4 58-22-0 6013
3
Citalopram Approved Phase 4,Phase 2,Phase 3 59729-33-8 2771
4
Sertraline Approved Phase 4,Phase 2,Phase 3 79617-96-2 68617
5
Norepinephrine Approved Phase 4,Phase 2,Phase 3 51-41-2 439260
6
Bupropion Approved Phase 4,Phase 2,Phase 3 34841-39-9, 34911-55-2 444
7
Dopamine Approved Phase 4,Phase 2,Phase 3 51-61-6, 62-31-7 681
8
Fluoxetine Approved, Vet_approved Phase 4,Phase 2,Phase 3 54910-89-3 3386
9
Armodafinil Approved, Investigational Phase 4 112111-43-0
10
Modafinil Approved, Investigational Phase 4 68693-11-8 4236
11
Imipramine Approved Phase 4 50-49-7 3696
12
Paroxetine Approved, Investigational Phase 4,Phase 2 61869-08-7 43815
13
Donepezil Approved Phase 4 120014-06-4 3152
14 Anabolic Agents Phase 4
15 Androgens Phase 4
16 Antineoplastic Agents, Hormonal Phase 4
17 Hormone Antagonists Phase 4
18 Hormones Phase 4
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
20 Testosterone 17 beta-cypionate Phase 4
21
Testosterone enanthate Phase 4 315-37-7 9416
22 Testosterone undecanoate Phase 4
23 Antidepressive Agents Phase 4,Phase 2,Phase 3,Phase 1
24 Antidepressive Agents, Second-Generation Phase 4,Phase 2,Phase 3
25 Antiparkinson Agents Phase 4,Phase 2
26 Autonomic Agents Phase 4,Phase 2,Phase 1
27 Cholinergic Agents Phase 4,Phase 2,Phase 1
28 Cholinergic Antagonists Phase 4,Phase 2
29 Muscarinic Antagonists Phase 4,Phase 2
30 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1
31 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2,Phase 3
32 Parasympatholytics Phase 4,Phase 2
33 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1
34 Psychotropic Drugs Phase 4,Phase 2,Phase 3,Phase 1
35
Serotonin Phase 4,Phase 2,Phase 3 50-67-9 5202
36 Serotonin Agents Phase 4,Phase 2,Phase 3
37 Serotonin Uptake Inhibitors Phase 4,Phase 2,Phase 3
38 Desvenlafaxine Succinate Phase 4 386750-22-7
39 Serotonin and Noradrenaline Reuptake Inhibitors Phase 4,Phase 2,Phase 3
40 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 2,Phase 3
41 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
42 Dopamine Agents Phase 4,Phase 2,Phase 3
43 Dopamine Uptake Inhibitors Phase 4,Phase 2,Phase 3
44 Analgesics Phase 4
45 Duloxetine Hydrochloride Phase 4
46 Central Nervous System Stimulants Phase 4,Phase 1,Phase 2
47 Cytochrome P-450 CYP3A Inducers Phase 4
48 Wakefulness-Promoting Agents Phase 4
49 Venlafaxine Hydrochloride Phase 4,Phase 2,Phase 3
50 Adrenergic Agents Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 78)
id Name Status NCT ID Phase
1 Testosterone Replacement in Middle-Aged Hypogonadal Men With Dysthymia: Parallel Group, Double Blind Randomized Trial Unknown status NCT00260390 Phase 4
2 Medications for the Treatment of Dysthymic Disorder and Double Depression Unknown status NCT00234312 Phase 4
3 Desvenlafaxine vs. Placebo Treatment of Chronic Depression Unknown status NCT01537068 Phase 4
4 Wellbutrin XL for Dysthymic Disorder Completed NCT00225251 Phase 4
5 Escitalopram in the Treatment of Dysthymic Disorder, Double Blind Completed NCT00220701 Phase 4
6 Duloxetine Treatment in Elderly With Dysthymia Completed NCT01852383 Phase 4
7 Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression Completed NCT00518986 Phase 4
8 Duloxetine for Chronic Depression: a Double-blind Study Completed NCT00360724 Phase 4
9 Project to Improve Symptoms and Mood in People With Spinal Cord Injury Completed NCT00592384 Phase 4
10 Treatment of Depression Following Multiple Brain Tests Completed NCT00296777 Phase 4
11 Dichotic Listening as a Predictor of Medication Response in Depression Completed NCT00296725 Phase 4
12 Are Two Antidepressants a Good Initial Treatment for Depression? Completed NCT00296712 Phase 4
13 Dichotic Listening as a Predictor of Medication Response in Depression Completed NCT00404755 Phase 4
14 Efficacy Study Measuring The Impact Of Treatment With Viagra On The Depressive Symptoms Of Men With Erectile Dysfunction Completed NCT00159809 Phase 4
15 Paroxetine - Controlled Release in the Treatment of Irritable Bowel Syndrome (IBS) Completed NCT00610909 Phase 4
16 A Pilot Study Assessing Duloxetine's Efficacy in Atypical Depression Completed NCT00296699 Phase 4
17 Combination Treatment Study for Memory Impairment and Depression Completed NCT01658228 Phase 4
18 Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults Recruiting NCT01973283 Phase 4
19 Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders Active, not recruiting NCT00182533 Phase 4
20 Switching to Duloxetine to Ameliorate SSRI-Induced Sexual Dysfunction Terminated NCT00398632 Phase 4
21 A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults Withdrawn NCT01942187 Phase 4
22 Treating Depression Among Low-Income Patients With Cancer Unknown status NCT00565110 Phase 2, Phase 3
23 A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal Behavior Completed NCT01447602 Phase 3
24 A Stepped Care Model of Adolescent Depression Treatment in Primary Care Completed NCT01443715 Phase 2, Phase 3
25 Treatment of Adolescent Suicide Attempters (TASA) Completed NCT00080158 Phase 2, Phase 3
26 Safety and Tolerability of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder Completed NCT00707980 Phase 3
27 A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND} Recruiting NCT02358343 Phase 3
28 Effects of Therapist Behavior on the Treatment of Depressed Adolescents Unknown status NCT00073359 Phase 1, Phase 2
29 A Study of Omega-3 as a Treatment for Major Depression Unknown status NCT00238758 Phase 2
30 The Efficacy of Parent Involvement in the Treatment of Adolescent Depression Completed NCT00883519 Phase 1, Phase 2
31 New Approaches to Cocaine Abuse Medications (A) - 6 Completed NCT00000271 Phase 2
32 Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms Completed NCT01189812 Phase 2
33 Computerized Information-Processing Bias Retraining in Depressed Adolescents Completed NCT01147913 Phase 2
34 A Safety, Efficacy and Tolerability Study of SEP-225289 Completed NCT00584974 Phase 2
35 Group Interpersonal Psychotherapy for Depressed Adolescents in School-based Clinics Completed NCT00270244 Phase 2
36 Group Therapy for Women Prisoners With Comorbid Substance Use and Depression Completed NCT00606996 Phase 2
37 Bringing What Works to Youth in Corrections: A Trauma Intervention Completed NCT01560728 Phase 1, Phase 2
38 Smoking Cessation for Depressed Smokers Active, not recruiting NCT00494728 Phase 1, Phase 2
39 eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients Enrolling by invitation NCT02458690 Phase 2
40 Interpersonal Psychotherapy for Depressed Adolescents and Parents Completed NCT00619411 Phase 1
41 Motivational Interviewing to Improve Medication Adherence Among Hispanic Adults With Depression Completed NCT00356304 Phase 1
42 tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease Recruiting NCT02813629 Phase 1
43 Mindfulness Based Cognitive Therapy for Chronic Pain and Comorbid Unipolar Depression Unknown status NCT01473615
44 Desvenlafaxine Monotherapy in Dysthymia Completed NCT01948895
45 Duloxetine for the Treatment of Dysthymia Completed NCT00185575
46 Cognitive Behavioral Therapy (REBT/CBT) Evaluation for Dysthymia in the Practice of Clinical Social Work at Primary Care Completed NCT02112708
47 Enhanced Collaborative Depression Treatment in Primary Care: The RESPECT-D-E Trial Completed NCT01583400
48 Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused Intervention Completed NCT01542957
49 Cognitive Behavioral Therapy for Early-Onset Depression Completed NCT00096642
50 Improving Depression Care for Elders: Coordinating Center Completed NCT01561105

Search NIH Clinical Center for Dysthymic Disorder

Cochrane evidence based reviews: dysthymic disorder

Genetic Tests for Dysthymic Disorder

Anatomical Context for Dysthymic Disorder

MalaCards organs/tissues related to Dysthymic Disorder:

39
Brain

Publications for Dysthymic Disorder

Articles related to Dysthymic Disorder:

(show top 50) (show all 115)
id Title Authors Year
1
Changes in cytokine and chemokine expression distinguish dysthymic disorder from major depression and healthy controls. ( 27992767 )
2017
2
Cognitive Vulnerability in Patients with Generalized Anxiety Disorder, Dysthymic Disorder and Normal Individuals. ( 27045393 )
2016
3
Assessment of Quality of Life (QOL) in Obsessive Compulsive Disorder (OCD) and Dysthymic Disorder (DD): A Comparative Study. ( 26155540 )
2015
4
Relationship of quality of life with disability grade in obsessive compulsive disorder and dysthymic disorder. ( 25191009 )
2014
5
An open treatment trial of duloxetine in elderly patients with dysthymic disorder. ( 25177490 )
2014
6
Frontoparietal function in young people with dysthymic disorder (DSM-5: Persistent depressive disorder) during spatial working memory. ( 24709020 )
2014
7
Add-on deep transcranial magnetic stimulation (dTMS) in patients with dysthymic disorder comorbid with alcohol use disorder: A comparison with standard treatment. ( 25140585 )
2014
8
The re-labelling of dysthymic disorder to persistent depressive disorder in DSM-5: old wine in new bottles? ( 24270481 )
2014
9
Dysthymic disorder in the elderly population. ( 24152873 )
2014
10
Paroxetine in the treatment of dysthymic disorder without co-morbidities: A double-blind, placebo-controlled, flexible-dose study. ( 23466114 )
2013
11
Efficacy of add-on deep transcranial magnetic stimulation in comorbid alcohol dependence and dysthymic disorder: three case reports. ( 23724355 )
2013
12
Controlled randomized clinical trial of spirituality integrated psychotherapy, cognitive-behavioral therapy and medication intervention on depressive symptoms and dysfunctional attitudes in patients with dysthymic disorder. ( 24516853 )
2013
13
An examination of generalized anxiety disorder and dysthymic disorder by latent class analysis. ( 24020863 )
2013
14
L-acetylcarnitine in dysthymic disorder in elderly patients: a double-blind, multicenter, controlled randomized study vs. fluoxetine. ( 23428336 )
2013
15
Are there temperament differences between major depression and dysthymic disorder in adolescent clinical outpatients? ( 21839431 )
2012
16
Are there meaningful differences between major depressive disorder, dysthymic disorder, and their subthreshold variants? ( 22922240 )
2012
17
The categorisation of dysthymic disorder: can its constituents be meaningfully apportioned? ( 22835850 )
2012
18
Antidepressants for major depressive disorder and dysthymic disorder in patients with comorbid alcohol use disorders: a meta-analysis of placebo-controlled randomized trials. ( 21536001 )
2011
19
Treatment of major depressive disorder and dysthymic disorder with antidepressants in patients with comorbid opiate use disorders enrolled in methadone maintenance therapy: a meta-analysis. ( 21869696 )
2011
20
Four cases of dysthymic disorder and general malaise successfully treated with traditional herbal (kampo) medicines: kamiuntanto. ( 21614161 )
2010
21
The epidemiology of chronic major depressive disorder and dysthymic disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. ( 21190638 )
2010
22
Trajectories of recovery of social and physical functioning in major depression, dysthymic disorder and double depression: a 3-year follow-up. ( 19945171 )
2010
23
The impact of comorbid dysthymic disorder on outcome in personality disorders. ( 20728000 )
2010
24
Impairment in psychosocial functioning associated with dysthymic disorder in the NESARC study. ( 20471093 )
2010
25
Escitalopram versus placebo in the treatment of dysthymic disorder. ( 21811192 )
2010
26
Plasma levels of brain-derived neurotrophic factor and interleukin-6 in patients with dysthymic disorder: comparison with age- and sex-matched major depressed patients and healthy controls. ( 21312291 )
2010
27
The association of visuospatial working memory with dysthymic disorder in pre-pubertal children. ( 19607749 )
2010
28
Do major depressive disorder and dysthymic disorder confer differential risk for suicide? ( 18842304 )
2009
29
The three-year naturalistic course of major depressive disorder, dysthymic disorder and double depression. ( 19042028 )
2009
30
Dysthymic disorder: forlorn and overlooked? ( 19724735 )
2009
31
The effects of dysthymic disorder on health-related quality of life and disability days in persons with comorbid medical conditions in the general population. ( 19270471 )
2009
32
Comparison of prototypic cases of depressive personality disorder and dysthymic disorder. ( 18825775 )
2008
33
Dysthymic disorder and double depression: prediction of 10-year course trajectories and outcomes. ( 17466334 )
2008
34
Plasma testosterone and dehydroepiandrosterone sulfate in male and female patients with dysthymic disorder. ( 17182106 )
2007
35
Ten-year prospective follow-up study of the naturalistic course of dysthymic disorder and double depression. ( 16648329 )
2006
36
Attention deficit hyperactivity disorder, combined type, dysthymic disorder and anxiety disorders: differential patterns of neurodevelopmental deficits. ( 16876876 )
2006
37
Comparison of psychosocial correlates in primary school age children with attention deficit/ hyperactivity disorder- combined type, with and without dysthymic disorder. ( 16755402 )
2006
38
Randomized, double-blind, placebo-controlled trial of fluoxetine treatment for elderly patients with dysthymic disorder. ( 15653941 )
2005
39
Mental health service use by patients with dysthymic disorder: treatment use and dropout in a 7 1/2-year naturalistic follow-up study. ( 16175754 )
2005
40
Dysthymic disorder contributes to oppositional defiant behaviour in children with Attention Deficit Hyperactivity Disorder, combined type (ADHD-CT). ( 15935256 )
2005
41
Longitudinal comparison of depressive personality disorder and dysthymic disorder. ( 16175753 )
2005
42
Characteristics of internalizing and externalizing disorders in medication-naive, clinically referred children with attention deficit hyperactivity disorder, combined type and dysthymic disorder. ( 15860023 )
2005
43
A growth curve analysis of the course of dysthymic disorder: the effects of chronic stress and moderation by adverse parent-child relationships and family history. ( 15612848 )
2004
44
An open treatment trial of venlafaxine for elderly patients with dysthymic disorder. ( 15533993 )
2004
45
Citalopram in the treatment of dysthymic disorder. ( 15107656 )
2004
46
Trait and state aspects of harm avoidance and its implication for treatment in major depressive disorder, dysthymic disorder, and depressive personality disorder. ( 15149288 )
2004
47
Psychopathology in the adolescent and young adult offspring of parents with dysthymic disorder and major depressive disorder. ( 15091300 )
2004
48
Late onset dysthymic disorder and major depression differ from early onset dysthymic disorder and major depression in elderly outpatients. ( 15013252 )
2004
49
Which anxiety disorders may differentiate attention deficit hyperactivity disorder, combined type with dysthymic disorder from attention deficit hyperactivity disorder, combined type alone? ( 14511084 )
2003
50
Phenomenology and comorbidity of dysthymic disorder in 100 consecutively referred children and adolescents: beyond DSM-IV. ( 12655907 )
2003

Variations for Dysthymic Disorder

Expression for Dysthymic Disorder

Search GEO for disease gene expression data for Dysthymic Disorder.

Pathways for Dysthymic Disorder

GO Terms for Dysthymic Disorder

Biological processes related to Dysthymic Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.43 GATA3 HTR2A SLC6A4
2 memory GO:0007613 9.32 HTR2A SLC6A4
3 phosphatidylinositol 3-kinase signaling GO:0014065 9.16 GATA3 HTR2A
4 smooth muscle contraction GO:0006939 8.96 HTR2A HTR7
5 vasoconstriction GO:0042310 8.62 HTR7 SLC6A4

Molecular functions related to Dysthymic Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 G-protein coupled serotonin receptor activity GO:0004993 9.16 HTR2A HTR7
2 neurotransmitter receptor activity GO:0030594 8.96 HTR2A HTR7
3 serotonin binding GO:0051378 8.62 HTR2A HTR7

Sources for Dysthymic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....