EAF
MCID: EF001
MIFTS: 18

Eaf (EAF) malady

Summaries for Eaf

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32MalaCards
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MalaCards: Eaf, also known as sinonasal eosinophilic angiocentric fibrosis, is related to lacrimal duct obstruction and kimura disease. An important gene associated with Eaf is CD22 (CD22 molecule).

Aliases & Classifications for Eaf

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

eaf 42
sinonasal eosinophilic angiocentric fibrosis 42
disorder characterized by eosinophilia 60
eosinophilic angiocentric fibrosis 42


Related Diseases for Eaf

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17GeneCards, 18GeneDecks
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Diseases related to Eaf via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1lacrimal duct obstruction10.2
2kimura disease10.1
3loeffler endocarditis10.1
4hepatocellular fibrolamellar carcinoma10.1
5eosinophilia10.1
6eosinophilic cryptitis10.1
7familial eosinophilia10.1
8leopard syndrome10.0
9asthma10.0
10mastitis10.0
11deafness onychodystrophy osteodystrophy and mental retardation syndrome10.0

Graphical network of diseases related to Eaf:



Diseases related to eaf

Clinical Features for Eaf

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Drugs & Therapeutics for Eaf

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Eaf

Search CenterWatch for Eaf

Genetic Tests for Eaf

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Anatomical Context for Eaf

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Animal Models for Eaf or affiliated genes

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Publications for Eaf

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Genetic Variations for Eaf

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Expression for genes affiliated with Eaf

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Eaf

Search GEO for disease gene expression data for Eaf.

Pathways for genes affiliated with Eaf

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Compounds for genes affiliated with Eaf

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GO Terms for genes affiliated with Eaf

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Sources:
16Gene Ontology
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Cellular components related to Eaf according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ELL-EAF complexGO:03278310.1EAF2, EAF1
2NuA4 histone acetyltransferase complexGO:0352679.8MEAF6, ING3
3nucleusGO:0056348.8VPS72, TFPT, PHF12, MEAF6, AIRE, H2AFZ

Biological processes related to Eaf according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1histone H4-K16 acetylationGO:04398410.1MSL3, MEAF6
2regulation of DNA-dependent transcription, elongationGO:03278410.0TCEA1, TCEA2
3histone H2A acetylationGO:0439689.8ING3, MEAF6
4transcription, DNA-dependentGO:0063519.3EAF1, VPS72, TFPT, MEAF6, AIRE, ING3

Molecular functions related to Eaf according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1DNA bindingGO:0036779.4VPS72, TFPT, H2AFZ, TCEA2, TCEA1, MSL3
2protein bindingGO:0055158.4VPS72, TFPT, PHF12, MEAF6, AIRE, CD22

Products for genes affiliated with Eaf

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Eaf

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet