MCID: EF001
MIFTS: 25

Eaf malady

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Eaf

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Sources:
45NIH Rare Diseases, 51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Eaf:

Name: Eaf 45
Eosinophilic Angiocentric Fibrosis 45 51
 
Igg4-Related Eosinophilic Angiocentric Fibrosis 51
Sinonasal Eosinophilic Angiocentric Fibrosis 45

Classifications:



External Ids:

Orphanet51 449566
ICD10 via Orphanet28 J39.8

Summaries for Eaf

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MalaCards based summary: Eaf, also known as eosinophilic angiocentric fibrosis, is related to leopard syndrome and deafness onychodystrophy osteodystrophy and mental retardation syndrome. An important gene associated with Eaf is EAF1 (ELL Associated Factor 1). Affiliated tissues include breast, bone and endothelial.

Related Diseases for Eaf

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Diseases related to Eaf via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1leopard syndrome10.0
2deafness onychodystrophy osteodystrophy and mental retardation syndrome10.0
3lacrimal duct obstruction10.0
4asthma9.9
5mastitis9.9
6eagle syndrome9.5EAF1, EAF2

Graphical network of diseases related to Eaf:



Diseases related to eaf

Symptoms for Eaf

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Drugs & Therapeutics for Eaf

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Drugs for Eaf (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ApremilastPhase 158608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
2Peripheral Nervous System AgentsPhase 118510
3Antirheumatic AgentsPhase 18496
4Anti-Inflammatory Agents, Non-SteroidalPhase 13549
5Analgesics, Non-NarcoticPhase 15184
6Anti-Inflammatory AgentsPhase 18478
7AnalgesicsPhase 19358

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study to Evaluate Pharmacokinetics of Apremilast in Heatlhy Male SubjectsCompletedNCT02236988Phase 1
2Study of Ventilatory Mechanics in Patients With Sickle Cell AnemiaCompletedNCT02565849
3Exercise and PTSD in Older VeteransRecruitingNCT02295995

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Genetic Tests for Eaf

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Anatomical Context for Eaf

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MalaCards organs/tissues related to Eaf:

33
Breast, Bone, Endothelial, Myeloid, Liver, Pituitary, Temporal lobe

Animal Models for Eaf or affiliated genes

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Publications for Eaf

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Articles related to Eaf:

(show all 40)
idTitleAuthorsYear
1
Health status of male steel workers at an electric arc furnace (EAF) in Trentino, Italy. (26900394)
2016
2
A Study on Suitability of EAF Oxidizing Slag in Concrete: An Eco-Friendly and Sustainable Replacement for Natural Coarse Aggregate. (26421315)
2015
3
Hydrometallurgical extraction of zinc from CaO treated EAF dust in ammonium chloride solution. (26448494)
2015
4
CO2 sequestration using accelerated gas-solid carbonation of pre-treated EAF steel-making bag house dust. (25846002)
2015
5
Studies on Antifungal Potential, Primary Characterization and Mode of Action of a De Novo Cytoplasmic Protein (EAF) from Human Commensal Escherichia coli Against Aspergillus spp. (26235093)
2015
6
Genetic analysis of enteropathogenic Escherichia coli (EPEC) adherence factor (EAF) plasmid reveals a new deletion within the EAF probe sequence among O119 typical EPEC strains. (26438110)
2015
7
Crystallization Control for Remediation of an FetO-rich CaO-SiO2-Al2O3-MgO EAF Waste Slag. (24410350)
2014
8
Recycling of Malaysia's electric arc furnace (EAF) slag waste into heavy-duty green ceramic tile. (25242607)
2014
9
Study on simultaneous recycling of EAF dust and plastic waste containing TBBPA. (24945793)
2014
10
The efficiency of quartz addition on electric arc furnace (EAF) carbon steel slag stability. (25113518)
2014
11
Reduction behavior of zinc ferrite in EAF-dust recycling with CO gas as a reducing agent. (24921184)
2014
12
Characterisation of the sintering behaviour of Waelz slag from electric arc furnace (EAF) dust recycling for use in the clay ceramics industry. (24321287)
2014
13
Accelerated ageing of an EAF black slag by carbonation and percolation for long-term behaviour assessment. (24726964)
2014
14
Heavy metal adsorption changes of EAF steel slag after phosphorus adsorption. (22508118)
2012
15
The use of EAF dust in cement composites: assessment of environmental impact. (19097693)
2009
16
Pathology quiz case 2. Eosinophilic angiocentric fibrosis (EAF). (19620599)
2009
17
Virulence features of atypical enteropathogenic Escherichia coli identified by the eae(+) EAF-negative stx(-) genetic profile. (19442475)
2009
18
Reproducing ten years of road ageing--accelerated carbonation and leaching of EAF steel slag. (19539979)
2009
19
A novel method to enhance polychlorinated dibenzo-p-dioxins and dibenzofurans removal by adding bio-solution in EAF dust treatment plant. (17532560)
2008
20
Role of extension arm in PEG-Hb conjugates on the stability of the tetramer: non-conservative EAF maleimide thio-PEG mediated PEGylation. (19085194)
2008
21
New evidence for rejuvenation of phosphorus retention capacity in EAF steel slag. (18767686)
2008
22
Use of EAF dust as heterogeneous catalyst in Fenton oxidation of PCP contaminated wastewaters. (16621261)
2006
23
Hydrometallurgical processing of carbon steel EAF dust. (16442223)
2006
24
Combined glassification of EAF dust and incinerator fly ash. (12656228)
2003
25
Study of the presence of fluorine in the recycled fractions during carbothermal treatment of EAF dust. (12909089)
2003
26
O-serogroups, eae gene and EAF plasmid in Escherichia coli isolates from cases of bovine mastitis in Brazil. (11844619)
2002
27
Interactions of Escherichia coli strains of non-EPEC serogroups that carry eae and lack the EAF and stx gene sequences with undifferentiated and differentiated intestinal human Caco-2 cells. (11410359)
2001
28
Assessment of industrial effluent toxicity using flow-through fish egg/alevins/fry (EAF) Toxicity Test. (10094727)
1999
29
Linkage assignment of the last unmapped cattle erythrocyte antigen system, EAF. (10582299)
1999
30
High tibial osteotomy: osteotomy in minus or hemicallotasis with EAF? (8968118)
1996
31
Survey of cytotoxin production among Escherichia coli strains characterized as enteropathogenic (EPEC) by serotyping and presence of EPEC adherence factor (EAF) sequences. (7520828)
1994
32
DNA probe analysis of diarrhoeagenic Escherichia coli: detection of EAF-positive isolates of traditional enteropathogenic E. coli serotypes among Bangladeshi paediatric diarrhoea patients. (1513347)
1992
33
Effects of methanol extract of ginkgo biloba (EGb), its ethylacetate fraction (EAF) and butanol fraction (BF) on the isolated aorta. (1507615)
1992
34
The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid. (1682258)
1991
35
Production of eosinophil-activating factor (EAF) by peripheral blood mononuclear cells from asthma patients. (2613341)
1989
36
Eosinophil-activating factor (EAF) production by a human cell line (ESH 98) stimulated with tumour necrosis factor. (2450839)
1988
37
Fimbria-like adhesive factor (EAF 44) from verocytotoxigenic Escherichia coli of bovine origin. (2905510)
1988
38
A comparison of eosinophil-activating factor (EAF) with other monokines and lymphokines. (3489622)
1986
39
Fc-receptor-bearing cells in spleen of mice injected with cell-free Ehrlich ascites fluid (EAF). (6448644)
1980
40

Variations for Eaf

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Expression for genes affiliated with Eaf

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Search GEO for disease gene expression data for Eaf.

Pathways for genes affiliated with Eaf

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GO Terms for genes affiliated with Eaf

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Cellular components related to Eaf according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:00056549.1EAF1, EAF2

Sources for Eaf

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet