MCID: ECC004
MIFTS: 33

Eccrine Porocarcinoma malady

Categories: Rare diseases, Skin diseases, Cancer diseases

Aliases & Classifications for Eccrine Porocarcinoma

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Aliases & Descriptions for Eccrine Porocarcinoma:

Name: Eccrine Porocarcinoma 11 48 50 39 13 68
Eccrine Porocarcinoma of Skin 11 48
 
Malignant Eccrine Poroma 11 48
Porocarcinoma 11 48

Classifications:



External Ids:

Disease Ontology11 DOID:7566
MeSH39 D057090
NCIt45 C5560

Summaries for Eccrine Porocarcinoma

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NIH Rare Diseases:48 Eccrine porocarcinoma is a rare type of skin cancer that may occur by chance or may develop from a benign (non-cancerous) skin tumor. They affect the eccrine sweat glands, which are the major sweat glands of the body. Eccrine porocarcinoma usually are found in adults older than 60 and appear as a single red elevated solid mass (nodule) or a thickened or elevated lesion (plaque). They are found anywhere on the body, but occur most commonly on the lower limbs, head, and upper limbs. Most people with an eccrine porocarcinoma do not have symptoms; however some individuals may notice bleeding from the tumor or itching. Factors that may increase the risk to develop an eccrine porocarcinoma include family history, suppression of the immune system, and exposure to ultraviolet light or radiation. Treatment usually involves surgery to remove the tumor. Last updated: 12/13/2016

MalaCards based summary: Eccrine Porocarcinoma, also known as eccrine porocarcinoma of skin, is related to vulvar eccrine porocarcinoma and hypotonia. An important gene associated with Eccrine Porocarcinoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways is Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include skin, lymph node and colon.

Wikipedia:71 A malignant acrospiroma (also known as hidradenocarcinoma, and \"Spiradenocarcinoma\") is a sweat gland... more...

Related Diseases for Eccrine Porocarcinoma

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Diseases related to Eccrine Porocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1vulvar eccrine porocarcinoma12.2
2hypotonia10.4S100B, VIM
3exstrophy-epispadias complex10.4S100B, VIM
4absence of fingerprints congenital milia10.4S100B, VIM
5fraxf syndrome10.4S100B, VIM
6pulmonary venoocclusive disease10.4S100B, VIM
7malignant adenofibroma10.4S100B, VIM
8pineal parenchymal tumor of intermediate differenciation10.3S100B, VIM
9epithelioid cell melanoma10.3S100B, VIM
10ebola hemorrhagic fever10.3KRT1, KRT10
11ichthyosis histrix, curth-macklin type10.3KRT1, KRT10
12bradyopsia10.3KRT1, KRT10
13pauciarticular onset juvenile idiopathic arthritis10.3S100B, VIM
14osteopetrosis and infantile neuroaxonal dystrophy10.3S100B, VIM
15brachydactyly type a310.3KRT1, KRT10
162q33.1 microdeletion syndrome10.3MUC1, VIM
17hemoglobin d disease10.3KRT1, KRT10
18telangiectasia, hereditary hemorrhagic, type 210.3KRT1, KRT10
19emerinopathy10.3S100B, VIM
20novak syndrome10.3S100B, VIM
21distal monosomy 7q3610.3MUC1, VIM
22transitional meningioma10.3MUC1, VIM
23monophasic synovial sarcoma10.2MUC1, VIM
24congenital structural myopathy10.2MUC1, VIM
25skin sarcoma10.2MUC1, VIM
26extracranial neuroblastoma10.2MUC1, VIM
27pineoblastoma10.2MUC1, VIM
28benign mesenchymoma10.2MUC1, VIM
29ovarian surface papilloma10.2MUC1, VIM
30ovarian cystadenocarcinoma10.2MUC1, VIM
31logopenic progressive aphasia10.2MUC1, S100B
32intermediate dend syndrome10.2MUC1, S100B
33lyme disease - neurological complications10.2MUC1, S100B
34relapsing epidemic typhus10.2MUC1, S100B
35colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas10.2KRT1, KRT10
36parachordoma10.2MUC1, VIM
37vascular hemostatic disease10.2MUC1, VIM
38angora hair nevus10.2MUC1, VIM
39pituitary deficiency due to rathke's pouch cysts10.2MUC1, S100B
40short-rib thoracic dysplasia 1210.2MUC1, VIM
41subacute leukemia10.2MUC1, S100B
42pseudoglandular variant testicular seminoma10.2MUC1, S100B
43external ear disease10.2MUC1, S100B
44serous cystadenocarcinoma10.2MUC1, VIM
45primary syphilis10.2MUC1, VIM
46penis verrucous carcinoma10.1MUC1, S100B
47breast papillary carcinoma10.1MUC1, S100B
48bowen's disease10.1
49pediatric meningioma10.1MUC1, VIM
50neutrophil immunodeficiency syndrome10.1S100B, VIM

Graphical network of the top 20 diseases related to Eccrine Porocarcinoma:



Diseases related to eccrine porocarcinoma

Symptoms & Phenotypes for Eccrine Porocarcinoma

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Drugs & Therapeutics for Eccrine Porocarcinoma

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Drugs for Eccrine Porocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
nivolumabapprovedPhase 2326946414-94-4
Synonyms:
BMS-936558
 
MDX-1106
ONO-4538
nivolumab
2ImmunoglobulinsPhase 26045
3Antibodies, MonoclonalPhase 23795
4AntibodiesPhase 26045

Interventional clinical trials:

idNameStatusNCT IDPhase
1Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin CancersNot yet recruitingNCT02978625Phase 2

Search NIH Clinical Center for Eccrine Porocarcinoma


Cochrane evidence based reviews: eccrine porocarcinoma

Genetic Tests for Eccrine Porocarcinoma

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Anatomical Context for Eccrine Porocarcinoma

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MalaCards organs/tissues related to Eccrine Porocarcinoma:

36
Skin, Lymph node, Colon, Lung

Publications for Eccrine Porocarcinoma

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Articles related to Eccrine Porocarcinoma:

(show top 50)    (show all 136)
idTitleAuthorsYear
1
Dermoscopic and reflectance confocal microscopic presentation of relapsing eccrine porocarcinoma. (28087039)
2017
2
Eccrine Porocarcinoma Presenting as a Hand Cyst. (27593487)
2016
3
Eccrine Porocarcinoma of the Scalp: A Rare Case Report with Review of Literature. (26894080)
2016
4
Metastatic Eccrine Porocarcinoma: A Rare Case of Successful Treatment. (27721767)
2016
5
Eccrine porocarcinoma of the vulva: a case report and review of the literature. (27832810)
2016
6
Eccrine Porocarcinoma presenting as an abdominal wall mass in a patient with ulcerative colitis-A rare case report. (27085107)
2016
7
Eccrine porocarcinoma: A wolf in sheep's clothing. (25803156)
2015
8
Metastatic eccrine porocarcinoma successfully treated with carboplatin and epirubicin chemotherapy. (26073009)
2015
9
Eccrine Porocarcinoma of Scalp: a Rare Case Report. (26516328)
2015
10
In-transit metastasis of advanced eccrine porocarcinoma. (26234455)
2015
11
Eccrine porocarcinoma shares dermoscopic characteristics with eccrine poroma: A report of three cases and review of the published work. (26333057)
2015
12
Eccrine porocarcinoma: epidemiologic and histopathologic characteristics. (25515648)
2015
13
Eccrine Porocarcinoma Treated by Mohs Micrographic Surgery: Over 6-Year Follow-up of 12 Cases and Literature Review. (25984905)
2015
14
Eccrine porocarcinoma of the thumb in a patient with chronic exposure to benzene glue. (26078532)
2015
15
Response to taxane-based chemotherapy in metastatic eccrine porocarcinoma with extensive cutaneous involvement. (26837980)
2015
16
Eccrine porocarcinoma mimicking a venous leg ulcer. (26400442)
2015
17
Eccrine porocarcinoma with extensive cutaneous metastases. (26566927)
2015
18
A Case of Recurrent Eccrine Porocarcinoma with Regional Lymph Nodal Metastasis, Arising on a Bowen's Disease Patch. (25972690)
2015
19
Treatment of eccrine porocarcinoma with Mohs micrographic surgery: a cases series and literature review. (26205087)
2015
20
Mohs micrographic surgery for eccrine porocarcinoma: an update and review of the literature. (25742554)
2015
21
Intralesional Photodynamic Therapy for Eccrine Porocarcinoma. (26079590)
2015
22
Eccrine Porocarcinoma of the Eyelid in a Non-Caucasian Patient. (24841732)
2014
23
A Rare Case of Eccrine Porocarcinoma of the Eyelid. (24576261)
2014
24
Successful Treatment of Eccrine Porocarcinoma Metastasized to a Cervical Lymph Node with CyberKnife Radiosurgery. (25076888)
2014
25
Eccrine porocarcinoma: a report of 2 cases and review of the literature. (24505584)
2014
26
Eccrine poroma and eccrine porocarcinoma in linear epidermal nevus. (24803063)
2014
27
Zosteriform Metastases of Eccrine Porocarcinoma Mimicking Eruptive Seborrheic Keratoses. (24909550)
2014
28
Rapidly growing eccrine porocarcinoma of the face in a pregnant woman. (24621740)
2014
29
A case of eccrine porocarcinoma: usefulness of immunostain for s-100 protein in the diagnoses of recurrent and metastatic dedifferentiated lesions. (24003279)
2013
30
Eccrine porocarcinoma: clinical and pathological report of eight cases. (24403888)
2013
31
FDG PET/CT in Malignant Eccrine Porocarcinoma Arising in a Pre-existing Poroma. (23917787)
2013
32
Metastatic eccrine porocarcinoma. (24087778)
2013
33
Successful management of metastatic eccrine porocarcinoma. (24282649)
2013
34
Treatment of multiple bilateral primary eccrine porocarcinoma with topical diphencyprone: a case report. (23773127)
2013
35
Eccrine porocarcinoma: cytologic diagnosis by fine needle aspiration biopsy (FNAB). (24016659)
2013
36
Eccrine porocarcinoma: a case report. (24551693)
2013
37
Eccrine porocarcinoma with carcinomatous lymphangitis in a patient with history of arsenic exposure: a case report. (22108500)
2012
38
Case report of eccrine porocarcinoma in situ associated with eccrine poroma on the forehead. (22150617)
2012
39
Eccrine porocarcinoma arising within an area of Bowen disease. (21973218)
2012
40
Metastatic eccrine porocarcinoma after Mohs micrographic surgery: a case report. (22689795)
2012
41
Eccrine porocarcinoma of the lower extremity: a case report and review of literature. (21859481)
2011
42
Eccrine porocarcinoma of scalp: an uncommon tumor at an unusual site. (22693407)
2011
43
Primary eccrine porocarcinoma of the finger with transit forearm and axillary metastasis. (21042176)
2011
44
Eccrine porocarcinoma of the external ear. (21853429)
2011
45
Eccrine porocarcinoma of the vulva: a case report and review of literature. (21131825)
2011
46
Eccrine porocarcinoma presenting with unusual clinical manifestations: a case report and review of the literature. (22028580)
2011
47
Factors in the surgical management of primary eccrine porocarcinoma: prognostic histological factors can guide the surgical procedure. (21711331)
2011
48
Metastatic eccrine porocarcinoma: report of a case and review of the literature. (21410982)
2011
49
Dermoscopic features of eccrine porocarcinoma arising from hidroacanthoma simplex. (20976127)
2010
50
A case of clear cell eccrine porocarcinoma. (20711273)
2010

Variations for Eccrine Porocarcinoma

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Expression for genes affiliated with Eccrine Porocarcinoma

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Search GEO for disease gene expression data for Eccrine Porocarcinoma.

Pathways for genes affiliated with Eccrine Porocarcinoma

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Pathways related to Eccrine Porocarcinoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5S100B, VIM

GO Terms for genes affiliated with Eccrine Porocarcinoma

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Cellular components related to Eccrine Porocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058828.7KRT10, KRT15, VIM

Biological processes related to Eccrine Porocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1astrocyte differentiationGO:00487089.3S100B, STAT3

Molecular functions related to Eccrine Porocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.2KRT15, VIM

Sources for Eccrine Porocarcinoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet