MCID: ECH003
MIFTS: 49

Echinococcosis malady

Categories: Rare diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Echinococcosis

About this section

Aliases & Descriptions for Echinococcosis:

Name: Echinococcosis 10 12 36 2 65
Hydatidosis 10 45
Echinococcosis, Unspecified, of Liver 10
Liver Echinococcus Unspecified 10
Echinococcosis, Pulmonary 65
Pulmonary Echinococcosis 10
 
Echinococcosis, Hepatic 65
Echinococcosis of Liver 10
Hepatic Echinococcosis 10
Echinococcal Disease 10
Hydatid Disease 10
Hydatids 47

Classifications:



External Ids:

Disease Ontology10 DOID:1496
ICD1027 B67, B67.90, B67.8
ICD9CM29 122
MeSH36 D004443
NCIt42 C84682
UMLS65 C0013502, C0013504, C0013505

Summaries for Echinococcosis

About this section
Disease Ontology:10 A parasitic helminthiasis infectious disease that involves parasitic infection of humans and domestic animals caused by the larval stages of tapeworms of the genus Echinococcus in the liver, lungs, spleen, brain, heart and kidneys.

MalaCards based summary: Echinococcosis, also known as hydatidosis, is related to crohn's disease and pityriasis rosea. An important gene associated with Echinococcosis is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Cell adhesion molecules (CAMs) and Pertussis. The drug albendazole has been mentioned in the context of this disorder. Affiliated tissues include liver, lung and brain.

CDC:2 Echinococcosis is a parasitic disease caused by infection with tiny tapeworms of the genus Echinocococcus. Echinococcosis is classified as either cystic echinococcosis or alveolar echinococcosis.

Wikipedia:68 Echinococcosis, also called hydatid disease, hydatidosis, or echinococcal disease, is a parasitic... more...

Related Diseases for Echinococcosis

About this section

Diseases related to Echinococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 762)
idRelated DiseaseScoreTop Affiliating Genes
1crohn's disease30.2IL6, TNF
2pityriasis rosea30.2CD8A, HLA-DRB1
3bronchiolitis30.2HLA-B, IL6
4mycosis fungoides30.1HLA-B, IL10, TNF
5neutropenia30.1HLA-DRB1, IL17A, IL6
6meningitis30.1IL10, TLR2, TNF
7cryptosporidiosis30.0HLA-B, HLA-DRB1, TNF
8artery disease30.0HLA-B, HLA-DRB1, TNF
9sarcocystosis29.9HLA-B, IL10, IL6
10hypopharynx cancer29.8HLA-DRB1, IL6, TNF
11keratomalacia29.8HLA-DRB1, IL6, TNF
12periodontal disease29.6IL6, TLR2, TNF
13hemolytic anemia29.6HLA-B, IL10, IL6, TNF
14placental abruption29.6HLA-B, IL10, IL6, TNF
15methylmalonic acidemia29.6HLA-B, IL10, IL6, TNF
16bronchopulmonary dysplasia29.5IL10, IL17A, IL6, TNF
17obesity29.4IL10, IL17A, IL6, TLR2, TNF
18lateral sclerosis29.3HLA-DRB1, IL10, IL6, TLR2, TNF
19neurogenic bladder29.3IL10, IL6, TLR2, TNF
20rheumatoid arthritis29.1HLA-B, HLA-DRB1, IL10, IL17A, IL6, TLR2
21malaria28.7CD8A, HLA-B, HLA-DRB1, IL10, IL17A, IL6
22alveolar echinococcosis12.7
23cystic echinococcosis12.7
24polycystic echinococcosis12.5
25cardiac hydatid cysts with intracavitary expansion12.3
26postinfectious encephalomyelitis10.5HLA-B, HLA-DRB1
27idiopathic juxtafoveal retinal telangiectasia10.5HLA-B, HLA-DRB1
28psoriasis10.5HLA-B, HLA-DRB1
29intermediate uveitis10.5HLA-B, HLA-DRB1
30maculopapular lupus rash10.5HLA-DRB1, IL10
31congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome10.5HLA-DRB1, TNF
32dioctophymiasis10.4IL10, MT-CO1
33punctate palmoplantar keratoderma type 210.4IL10, TNF
34autoimmune polyglandular syndrome type 210.4HLA-DRB1, TNF
35best1 retinopathy10.4HLA-DRB1, TNF
36primary progressive freezing gait10.4IL10, TNF
37non-distal monosomy 10q10.4HLA-DRB1, TNF
38androgen insensitivity syndrome, mild10.4HLA-DRB1, TNF
39kearns-sayre syndrome10.4IL10, TNF
40finnish upper limb-onset distal myopathy10.4HLA-DRB1, IL17A
41acneiform dermatitis10.4HLA-B, TNF
42ureterocele10.4CD8A, TNF
43metanephric adenoma10.4HLA-B, HLA-DRB1
44multifocal lymphangioendotheliomatosis with thrombocytopenia10.4IL10, TNF
45alternating exotropia10.4IL10, TNF
46rhizomelic dysplasia patterson lowry type10.4HLA-DRB1, TNF
47glomangiomatosis10.4IL10, IL6
48catamenial pneumothorax10.4IL10, IL6
49hepatitis10.4
50multicentric osteolysis nephropathy10.3IL10, IL6

Graphical network of the top 20 diseases related to Echinococcosis:



Diseases related to echinococcosis

Symptoms for Echinococcosis

About this section

Drugs & Therapeutics for Echinococcosis

About this section

Drugs for Echinococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1BenzimidazoleexperimentalPhase 4451-17-25798
2Antiparasitic AgentsPhase 41854
3AnthelminticsPhase 4379
4Anti-Infective AgentsPhase 417220
5Liver Extracts3572

Interventional clinical trials:

idNameStatusNCT IDPhase
1Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With BenzimidazolesRecruitingNCT00658294Phase 4
2Laparoscopic Versus Open Surgery for the Management of Cystic Echinococcosis of the LiverCompletedNCT01643018
3Long-term Results of Comprehensive AE ManagementCompletedNCT02509884
4Epi Cystic Hydatid Disease PeruCompletedNCT00138346
5The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the LiverCompletedNCT01785212
6Parasitic Infections of the Gastrointestinal TractRecruitingNCT00001162

Search NIH Clinical Center for Echinococcosis

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: echinococcosis

Genetic Tests for Echinococcosis

About this section

Anatomical Context for Echinococcosis

About this section

MalaCards organs/tissues related to Echinococcosis:

33
Liver, Lung, Brain, Kidney, Heart, Spleen, Breast

Animal Models for Echinococcosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Echinococcosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Echinococcosis

About this section

Articles related to Echinococcosis:

(show top 50)    (show all 1042)
idTitleAuthorsYear
1
The Author's Response: Impact of Implementation of an Automated Liquid Culture System on the Diagnosis of Tuberculous Pleurisy. (27099883)
2015
2
Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme. (25366363)
2014
3
Adiponectin receptor 1 (ADIPOR1) rs1342387 polymorphism and risk of cancer: a meta-analysis. (25292021)
2014
4
Follow-up of serum KL-6 lung fibrosis biomarker levels in 173 patients with systemic sclerosis. (24773853)
2014
5
Orthostatic blood pressure dysregulation and polymorphisms of I^-adrenergic receptor genes in hypertensive patients. (24552127)
2014
6
SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia: independent prognostic impact in CMML. (23558523)
2013
7
Epidemiologic features and risk factors of Crimean-Congo hemorrhagic fever in Samsun province, Turkey. (23208513)
2013
8
Association of the ACE-II genotype with the risk of nephrotic syndrome in Pakistani children. (22033511)
2012
9
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease. (23251365)
2012
10
Osteochondroma with metaphyseal abnormalities after total body irradiation followed by stem cell transplantation. (22246151)
2012
11
Phase II study of sequential gemcitabine followed by docetaxel for recurrent Ewing sarcoma, osteosarcoma, or unresectable or locally recurrent chondrosarcoma: results of Sarcoma Alliance for Research Through Collaboration Study 003. (22363068)
2012
12
Performance of plasma fractionated free metanephrines by enzyme immunoassay in the diagnosis of pheochromocytoma and paraganglioma. (21742610)
2011
13
The effects of Robotic-Assisted Locomotor training on spasticity and volitional control. (22275643)
2011
14
Xanthoma disseminatum: effective therapy with 2-chlorodeoxyadenosine in a case series. (21173305)
2011
15
Critical role of G(alpha)12 and G(alpha)13 for human small cell lung cancer cell proliferation in vitro and tumor growth in vivo. (20160064)
2010
16
Strategies to maximize expression of rightly processed human interferon alpha2b in Pichia pastoris. (20159042)
2010
17
Effect of gene dosage on single-cell hippocampal electrophysiology in a murine model of SSADH deficiency (gamma-hydroxybutyric aciduria). (20363598)
2010
18
Hermansky-Pudlak syndrome. (20214008)
2009
19
The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. (19368795)
2009
20
Resistin up-regulates fractalkine expression in human endothelial cells: lack of additive effect with TNF-alpha. (19351602)
2009
21
Functional reconstitution of the human serotonin receptor 5-HT(6) using synthetic transmembrane peptides. (19836355)
2009
22
Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie (1886). (18683056)
2009
23
Immunohistochemical marker for Na+ CP type Valpha (C-20) and heterozygous nonsense SCN5A mutation W822X in a sudden cardiac death induced by mild anaphylactic reaction. (19318916)
2009
24
Development of lentiviral gene therapy for Wiskott Aldrich syndrome. (18194074)
2008
25
Effect of integrin alpha2beta1 on invasion and migration of neuroblastoma cells]. (18554474)
2008
26
Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo. (17565319)
2007
27
Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations. (17885617)
2007
28
PEG10 is a c-MYC target gene in cancer cells. (16423995)
2006
29
Laparoscopic environmental changes during surgery enhance the invasive potential of tumours. (15897689)
2005
30
A two-photon FRAP analysis of the cytoskeleton dynamics in the microvilli of intestinal cells. (15596489)
2005
31
Involvement of MAPK pathway in hypoxia-induced up-regulation of urokinase plasminogen activator receptor in a human prostatic cancer cell line, PC3MLN4. (15031672)
2004
32
Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily. (12945048)
2003
33
Surfactant protein D and KL-6 as serologic indicators of Pneumocystis carinii pneumonia in a child with acute lymphoblastic leukemia. (11321887)
2001
34
Cerebral atrophy related to corticotherapy in systemic lupus erythematosus (SLE). (11529629)
2001
35
Complementary and alternative therapies for the common cold. (11174218)
2001
36
Effective light-induced hydroxylamine reactions occur with C13 = C14 nonisomerizable bacteriorhodopsin pigments. (9649399)
1998
37
Maxillary hypoplasia with unsuspected choanal atresia. (9365973)
1997
38
Metronidazole and suramin combination in the treatment of arsenical refractory Rhodesian sleeping sickness--a case study. (8882195)
1996
39
Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells. (8643682)
1996
40
Cytokines in human lung fibrosis. (8678788)
1996
41
Precocious puberty in a case with probable Angelman syndrome. (7943614)
1994
42
Comparison of efficacy, secondary failure rate, and complications of sulfonylureas. (7833494)
1994
43
Hepoxilins. (8224734)
1993
44
Cloning and functional characterization of a human A1 adenosine receptor. (1530647)
1992
45
Cerebral atrophy and neuropsychological correlates in schizophrenia. (3452986)
1987
46
Human apolipoprotein A-II: complete nucleic acid sequence of preproapo A-II. (6090207)
1984
47
Leads from the MMWR. Infant botulism--Massachusetts. (6716572)
1984
48
Giant keratoacanthoma of the ear. (595076)
1977
49
Factors influenced on prognosis of reconstructive surgery for peripheral arterial occlusion: comparative study between arteriosclerosis obliterans and thromboangiitis obliterans. (599159)
1977
50

Variations for Echinococcosis

About this section

Expression for genes affiliated with Echinococcosis

About this section
Search GEO for disease gene expression data for Echinococcosis.

Pathways for genes affiliated with Echinococcosis

About this section

Pathways related to Echinococcosis according to GeneCards Suite gene sharing:

(show all 26)
idSuper pathwaysScoreTop Affiliating Genes
19.6CD8A, HLA-B, HLA-DRB1
29.3IL10, IL6, TNF
39.3IL10, IL6, TNF
49.3IL10, IL6, TNF
5
Show member pathways
9.1IL17A, IL6, TLR2
6
Show member pathways
9.1IL17A, IL6, TLR2
79.1IL6, TLR2, TNF
89.1CD8A, IL10, IL17A, TNF
99.1HLA-B, HLA-DRB1, IL6, TNF
109.0HLA-DRB1, IL10, IL6, TNF
11
Show member pathways
9.0IL6, MT-ATP6, MT-CO1, TNF
129.0CD8A, IL10, IL6, TNF
139.0CD8A, IL10, IL6, TNF
149.0CD8A, HLA-DRB1, IL6, TNF
15
Show member pathways
9.0HLA-DRB1, IL10, TLR2, TNF
16
Show member pathways
9.0IL10, IL17A, IL6, TNF
178.8IL10, IL6, TLR2, TNF
188.8IL10, IL6, TLR2, TNF
198.8IL10, IL6, TLR2, TNF
20
Show member pathways
8.7HLA-B, IL10, IL17A, IL6, TNF
21
Show member pathways
8.6HLA-B, IL10, IL17A, IL6, TNF
22
Show member pathways
8.5HLA-B, HLA-DRB1, IL6, TLR2, TNF
238.5HLA-DRB1, IL10, IL6, TLR2, TNF
24
Show member pathways
8.4IL10, IL17A, IL6, TLR2, TNF
258.4HLA-DRB1, IL17A, IL6, TLR2, TNF
26
Show member pathways
7.5CD8A, HLA-B, HLA-DRB1, IL10, IL17A, IL6

GO Terms for genes affiliated with Echinococcosis

About this section

Biological processes related to Echinococcosis according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1receptor biosynthetic processGO:003280010.4IL10, TNF
2negative regulation of cytokine secretion involved in immune responseGO:000274010.4IL10, TNF
3antigen processing and presentationGO:001988210.3HLA-B, HLA-DRB1
4defense response to protozoanGO:004283210.3IL10, IL6
5negative regulation of growth of symbiont in hostGO:004413010.2IL10, TNF
6epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.2IL6, TNF
7negative regulation of interleukin-6 productionGO:003271510.2IL10, TNF
8positive regulation of chemokine productionGO:003272210.1TLR2, TNF
9negative regulation of lipid storageGO:001088810.0IL6, TNF
10cellular response to hepatocyte growth factor stimulusGO:003572910.0IL10, IL6
11positive regulation of osteoclast differentiationGO:004567210.0IL17A, TNF
12response to glucocorticoidGO:00513849.7IL10, IL6, TNF
13T cell activationGO:00421109.7CD8A, IL6
14positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.7IL10, IL6, TNF
15agingGO:00075689.6IL10, IL6, MT-CO1
16defense response to Gram-positive bacteriumGO:00508309.5IL6, TLR2, TNF
17immune responseGO:00069557.8HLA-DRB1, IL10, IL17A, IL6, TLR2, TNF

Sources for Echinococcosis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet