MCID: ECL001
MIFTS: 57

Eclampsia

Categories: Rare diseases, Reproductive diseases, Cardiovascular diseases

Aliases & Classifications for Eclampsia

MalaCards integrated aliases for Eclampsia:

Name: Eclampsia 12 49 28 51 41 14 69
Eclampsia in Puerperium 12 69
Eclampsia, Postpartum 12
Postpartum Eclampsia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13593
ICD10 32 O15 O15.9 O15.2
MeSH 41 D004461
NCIt 46 C87167

Summaries for Eclampsia

Disease Ontology : 12 A pre-eclampsia characterized by the presence of seizures.

MalaCards based summary : Eclampsia, also known as eclampsia in puerperium, is related to preeclampsia/eclampsia 1 and severe pre-eclampsia, and has symptoms including seizures An important gene associated with Eclampsia is STOX1 (Storkhead Box 1), and among its related pathways/superpathways are VEGF binds to VEGFR leading to receptor dimerization and Warfarin Pathway, Pharmacodynamics. The drugs Methyldopa and Calcium Carbonate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, placenta and testes, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 72 Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is a... more...

Related Diseases for Eclampsia

Diseases in the Eclampsia family:

Pre-Eclampsia Severe Pre-Eclampsia

Diseases related to Eclampsia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 236)
# Related Disease Score Top Affiliating Genes
1 preeclampsia/eclampsia 1 34.1 EPHX1 PEE1
2 severe pre-eclampsia 32.9 ALB HLA-G LGALS13 PGF SERPINC1
3 placental insufficiency 30.5 F2 FLT1 PGF
4 hellp syndrome 29.9 EDN1 ENG F2 FLT1 LGALS13 MTHFR
5 microvascular complications of diabetes 5 29.7 ALB FLT1 PGF
6 hepatorenal syndrome 29.3 ALB EDN1 F2
7 thrombophilia 29.2 F2 MTHFR SERPINC1 THBD
8 antithrombin iii deficiency 29.1 F2 MTHFR SERPINC1
9 central retinal vein occlusion 29.1 F2 MTHFR SERPINC1
10 pulmonary edema 29.1 EDN1 F2 SERPINC1
11 portal vein thrombosis 29.1 F2 MTHFR SERPINC1
12 antiphospholipid syndrome 29.1 F2 MTHFR SERPINC1 THBD
13 retinal vein occlusion 29.1 F2 MTHFR SERPINC1
14 pre-eclampsia 28.8 C19orf33 CORIN EDN1 ENG EPHX1 F2
15 purpura 28.8 F2 SERPINC1 THBD
16 vascular disease 28.7 EDN1 MTHFR SERPINC1 THBD
17 placental abruption 28.6 ENG F2 FLT1 MTHFR PGF SERPINC1
18 thrombosis 28.6 F2 MTHFR SERPINC1 THBD
19 heart disease 28.2 ALB EDN1 F2 MTHFR SERPINC1
20 myocardial infarction 27.2 ALB EDN1 ENG F2 MTHFR PGF
21 preeclampsia/eclampsia 5 12.4
22 preeclampsia/eclampsia 4 12.3
23 mild pre-eclampsia 12.3
24 preeclampsia/eclampsia 2 11.9
25 preeclampsia/eclampsia 3 11.9
26 gestational diabetes 11.3
27 chorea gravidarum 10.9
28 glomeruloid hemangioma 10.5 ENG FLT1
29 twin-to-twin transfusion syndrome 10.5 ENG FLT1 PGF
30 endotheliitis 10.5
31 pregnancy loss, recurrent 1 10.4 HLA-G MTHFR
32 mesenteric vascular occlusion 10.4 F2 MTHFR
33 antipyrine metabolism 10.4 ALB F2
34 non-a-e hepatitis 10.4 ALB F2
35 livedoid vasculopathy 10.4 F2 MTHFR
36 ischemic neuropathy 10.3 F2 MTHFR
37 retinal vascular disease 10.3 ALB FLT1 MTHFR
38 abdominal tuberculosis 10.3 ALB F2
39 aging 10.2
40 parametritis 10.2 F2 OXT
41 uterine anomalies 10.2 MTHFR OXT PGF
42 kwashiorkor 10.2 ALB F2
43 encephalopathy 10.1
44 hypoxia 10.1
45 cerebritis 10.1
46 cortical blindness 10.1
47 hepatic tuberculosis 10.1 ALB F2
48 retinitis 10.1
49 diabetic angiopathy 10.0 EDN1 MTHFR THBD
50 bilirubin metabolic disorder 10.0 ALB F2 OXT

Graphical network of the top 20 diseases related to Eclampsia:



Diseases related to Eclampsia

Symptoms & Phenotypes for Eclampsia

UMLS symptoms related to Eclampsia:


seizures

MGI Mouse Phenotypes related to Eclampsia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.02 CORIN EDN1 ENG F2 FLT1 NOSTRIN
2 growth/size/body region MP:0005378 9.9 PGF TAC3 THBD CORIN EDN1 ENG
3 digestive/alimentary MP:0005381 9.86 OXT TAC3 THBD ALB EDN1 ENG
4 homeostasis/metabolism MP:0005376 9.83 ALB CORIN EDN1 ENG EPHX1 F2
5 integument MP:0010771 9.23 CORIN ENG F2 INHBB MTHFR OXT

Drugs & Therapeutics for Eclampsia

Drugs for Eclampsia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 357)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyldopa Approved Phase 4,Phase 2,Phase 1 555-30-6 38853
2
Calcium Carbonate Approved, Investigational Phase 4 471-34-1
3
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
4
Metformin Approved Phase 4,Phase 3 657-24-9 4091 14219
5
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
6
Dalteparin Approved Phase 4,Phase 2,Phase 3 9005-49-6
7
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 46507594 772
8
Bupivacaine Approved, Investigational Phase 4,Phase 3 38396-39-3, 2180-92-9 2474
9
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
10
Ephedrine Approved Phase 4,Phase 3 299-42-3 9294
11
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
12
Phenylephrine Approved Phase 4 59-42-7 6041
13
Pseudoephedrine Approved Phase 4,Phase 3 90-82-4 7028
14
Labetalol Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 36894-69-6 3869
15
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7487-88-9 24083
16
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
17
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
18
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
19
Captopril Approved Phase 4 62571-86-2 44093
20
Clonidine Approved Phase 4,Phase 1,Phase 2 4205-90-7 2803
21
Insulin Aspart Approved Phase 4,Phase 3 116094-23-6 16132418
22
Insulin Lispro Approved Phase 4 133107-64-9
23
Nifedipine Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 21829-25-4 4485
24
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
25
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
26
Thrombin Approved, Investigational Phase 4
27
Azithromycin Approved Phase 4,Phase 3 83905-01-5 53477736 447043 55185
28
Benzocaine Approved, Investigational Phase 4,Phase 3 1994-09-7, 94-09-7 2337
29
Desogestrel Approved Phase 4 54024-22-5 40973
30
Etonogestrel Approved, Investigational Phase 4 54048-10-1 6917715 40976
31
Amlodipine Approved Phase 4 88150-42-9 2162
32
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
33
leucovorin Approved, Nutraceutical Phase 4,Phase 3 58-05-9 143 6006
34
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2 67-97-0 10883523 5280795 6221
35
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2 50-14-6 5280793
36
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 1406-16-2
37 tannic acid Approved, Nutraceutical Phase 4,Phase 3
38 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Adrenergic Agonists Phase 4,Phase 2,Phase 3,Phase 1
41 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Phase 3,Phase 1
42 Adrenergic alpha-Agonists Phase 4,Phase 2,Phase 3,Phase 1
43 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
44 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
45 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Sympatholytics Phase 4,Phase 2,Phase 1,Early Phase 1
47 Bone Density Conservation Agents Phase 4,Phase 3,Phase 1,Phase 2
48 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
49 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
50 Analgesics, Opioid Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 448)

# Name Status NCT ID Phase Drugs
1 Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape) Unknown status NCT01361425 Phase 4 methildopa;placebo
2 Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia Unknown status NCT00117546 Phase 4 alpha methyldopa
3 Low Dose Calcium to Prevent Preeclampsia Unknown status NCT02338687 Phase 4
4 Remifentanil for General Anesthesia in Preeclamptics Unknown status NCT00567957 Phase 4 Remifentanil;Saline
5 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
6 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers Completed NCT01729468 Phase 4 Aspirin;Placebo
7 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients Completed NCT01972659 Phase 4 placebo;Magnesium Sulphate;sugammadex
8 Diuretics for Postpartum High Blood Pressure in Preeclampsia Completed NCT02163655 Phase 4 FUROSEMIDE;Placebo
9 Treatment Approaches to Preeclampsia Completed NCT01030627 Phase 4
10 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia Completed NCT01352234 Phase 4 Acetylsalicylic Acid;Acetylsalicylic Acid
11 Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies Completed NCT01608347 Phase 4 LMWH+Folic acid;Folic Acid
12 Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia Completed NCT02699827 Phase 4 Levobupivacaine hydrochloride;Magnesium sulphate;Saline 0.9%
13 A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen Completed NCT02091401 Phase 4 Magnesium Sulfate
14 Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia Completed NCT01408979 Phase 4 Magnesium sulfate 12 hours;Magnesium sulfate 24 hours
15 A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia Completed NCT00403572 Phase 4
16 Hemodynamic Measurements in Women With Serious Preeclampsia Completed NCT00199810 Phase 4
17 Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure Completed NCT01761916 Phase 4 CLONIDINE;CAPTOPRIL
18 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
19 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
20 Phenylephrine Versus Ephedrine in Pre-eclampsia Recruiting NCT02025426 Phase 4 Phenylephrine;Ephedrine
21 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Recruiting NCT03164304 Phase 4 Magnesium Sulfate
22 Impact of Antichlamydial Treatment on the Rate of Preeclampsia Recruiting NCT03233880 Phase 4 Azithromycin 1gm
23 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
24 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Recruiting NCT02920593 Phase 4 Vitamin D3
25 Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy Recruiting NCT01912677 Phase 4 Nifedipine;Labetalol;Methyldopa
26 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy Active, not recruiting NCT02891174 Phase 4 Ibuprofen;Acetaminophen
27 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Active, not recruiting NCT02911701 Phase 4 Acetaminophen;Ibuprofen
28 Contraception in Women With Sickle Cell Disease Active, not recruiting NCT02594462 Phase 4 etonogestrel-releasing implant contraceptive
29 Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation Active, not recruiting NCT02353806 Phase 4 Amlodipine besylate
30 Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial Not yet recruiting NCT03318211 Phase 4 Magnesium Sulfate
31 Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients Not yet recruiting NCT03237000 Phase 4 MgSO4
32 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
33 LMWH to Prevent Preeclampsia and Fetal Growth Restriction Terminated NCT00260520 Phase 4 Dalteparin
34 Atenativ Effect on Uterine Blood Flow and Preeclampsia Withdrawn NCT02278575 Phase 4 Atenativ
35 Investigating the Novel Observation of Right-Left Difference in Uterine Artery Vascular Resistance in Pre-Eclampsia Unknown status NCT00848679 Phase 3 Epidural lidocaine;Epidural lidocaine 2%
36 Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine Unknown status NCT00409253 Phase 3 URAPIDIL (EUPRESSYL*);NICARDIPINE
37 Randomized Clinical Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. Unknown status NCT02050529 Phase 2, Phase 3 Labetalol;Hydralazine
38 Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia Unknown status NCT01382732 Phase 3 Carbetocin;Oxytocin
39 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
40 Low Dose Aspirin for the Prevention of Preeclampsia Unknown status NCT01890005 Phase 3 Aspirin;Placebo
41 PP13 and Doppler Study to Predict Preeclampsia Unknown status NCT00928213 Phase 2, Phase 3 Progesterone;Low molecular weight Heparin;No Drug
42 Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases Unknown status NCT00872365 Phase 2, Phase 3
43 Folic Acid Dosage and Malformations Reduction Unknown status NCT01244347 Phase 3 folic acid;folic acid
44 New Magnesium Sulphate Protocol for Pre-eclampsia Completed NCT01846156 Phase 3 MgSO4
45 Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction Completed NCT00197340 Phase 3 Epidural ropivacaine
46 Magnesium Sulfate in Pregnancy and Postpartum Completed NCT02317146 Phase 2, Phase 3 Magnesium Sulfate
47 Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia Completed NCT01988298 Phase 2, Phase 3 Ibuprofen;Acetaminophen
48 L-Arginine in Pre-Eclampsia Completed NCT00157521 Phase 3 L-arginine
49 Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention Completed NCT02301780 Phase 3 Aspirin;Placebo
50 Induction With Foley OR Misoprostol (INFORM) Study Completed NCT01801410 Phase 3 Misoprostol

Search NIH Clinical Center for Eclampsia

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: eclampsia

Genetic Tests for Eclampsia

Genetic tests related to Eclampsia:

# Genetic test Affiliating Genes
1 Eclampsia 28

Anatomical Context for Eclampsia

MalaCards organs/tissues related to Eclampsia:

38
Endothelial, Placenta, Testes, Kidney, Lung, Liver, Heart

Publications for Eclampsia

Articles related to Eclampsia:

(show top 50) (show all 1724)
# Title Authors Year
1
Elabela-APJ axis contributes to embryonic development and prevents pre-eclampsia in pregnancy. ( 29342224 )
2018
2
Severe tricuspid regurgitation and seizure on postpartum day 10: case report of late postpartum eclampsia. ( 29451101 )
2018
3
Re: Placental histopathology associated with pre-eclampsia: a systematic review and meta-analysis. ( 29417682 )
2018
4
Pre-Eclampsia and Eclampsia: An Update on the Pharmacological Treatment Applied in Portugal. ( 29367581 )
2018
5
Maternal cardiac output response to colloid preload and vasopressor therapy during spinal anaesthesia for caesarean section in patients with severe pre-eclampsia: a randomised, controlled trial. ( 29086911 )
2018
6
Decidual regulation of trophoblast is altered in pregnancies at risk of pre-eclampsia. ( 29437882 )
2018
7
Association between fetal fraction on cell-free DNA testing and first trimester markers for pre-eclampsia. ( 29318732 )
2018
8
Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia. ( 29304392 )
2018
9
Induction of systemic inflammation by hyaluronan and hsp70 in women with pre-eclampsia. ( 29438905 )
2018
10
A computerized algorithm to capture patient's past preeclampsia and eclampsia history from prenatal clinical notes. ( 29388496 )
2018
11
Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies. ( 29405972 )
2018
12
Pre-eclampsia affects procalcitonin production in placental tissue. ( 29427369 )
2018
13
Dexmedetomidine as a part of general anaesthesia for caesarean delivery in patients with pre-eclampsia: Efficacy and foetal outcome: a randomised double-blinded trial. ( 29432379 )
2018
14
A case of partial hydatidiform molar pregnancy with a placental diploid-triploid mosaicism associated with a euploid viable foetus complicated with severe pre-eclampsia. ( 29421928 )
2018
15
Pre-eclampsia and the risk of autism-spectrum disorder in offspring: meta-analysis. ( 29436313 )
2018
16
Study on the correlation between adipocyte fatty-acid binding protein, glucolipid metabolism, and pre-eclampsia. ( 29316087 )
2018
17
Prediction and prevention of pre-eclampsia in Asian subpopulation. ( 29442407 )
2018
18
Is it time to move towards non-invasive prenatal screening for Down syndrome and screening for pre-eclampsia? ( 29446241 )
2018
19
Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure. ( 29351212 )
2018
20
Serum amyloid A, procalcitonin, highly sensitive C reactive protein and tumor necrosis factor alpha levels and acute inflammatory response in patients with hemolysis, elevated liver enzymes, low platelet count (HELLP) and eclampsia. ( 29345041 )
2018
21
Twin gestation in a Swyer syndrome patient with superimposed pre-eclampsia. ( 29421927 )
2018
22
What are the metabolic precursors which increase the risk of pre-eclampsia and how could these be investigated further. ( 28855067 )
2017
23
Pre-eclampsia: Molecular events to biomarkers. ( 28924318 )
2017
24
Accuracy of competing risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. ( 28067011 )
2017
25
Circulating adipokines are associated with pre-eclampsia in women with type 1 diabetes. ( 28875223 )
2017
26
Shared biomarkers between female diastolic heart failure and pre-eclampsia: a systematic review and meta-analysis. ( 28451444 )
2017
27
Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion. ( 28232601 )
2017
28
Maternal bradycardia occurring prior to onset of HELLP syndrome in a woman with pre-eclampsia. ( 28501825 )
2017
29
Serious Visual (Ocular) Complications in Pre-eclampsia and Eclampsia. ( 28867885 )
2017
30
Response to: Using Carbon Monoxide Releasing Molecules in Models of Pre-Eclampsia: When Should We Be Monitoring Vascular Effects? ( 28911026 )
2017
31
Intensive Care Unit issues in eclampsia and HELLP syndrome. ( 28971026 )
2017
32
Oligohydramnios is an independent risk factor for perinatal morbidity among women with pre-eclampsia who delivered preterm. ( 29237307 )
2017
33
Re: Pre-eclampsia: an important risk factor for asymptomatic heart failure. C. Ghossein-Doha, J. van Neer, B. Wissink, N. Breetveld, L. J. de Windt, A. P. J. van Dijk, M. J. van der Vlugt, M. C. H. Janssen, W. M. Heidema, R. R. Scholten and M. E. A. Spaanderman. Ultrasound Obstet Gynecol 2017; 49: 143-149. ( 28058791 )
2017
34
Severe pre-eclampsia before 26A weeks of gestation: how should we counsel women? ( 28229528 )
2017
35
Pre-eclampsia is primarily a placental disorder: FOR: Pre-eclampsia is primarily a placental disorder. ( 28921791 )
2017
36
Evaluation of Placental mir-155-5p and Long Non-coding RNA sONE Expression in Patients with Severe Pre-eclampsia. ( 28868266 )
2017
37
A Triple Obstetric Challenge of Thoracopagus-Type Conjoined Twins, Eclampsia, and Obstructed Labor: A Case Report from Sub-Saharan Africa. ( 29359057 )
2017
38
Screening for pre-eclampsia in the first trimester: what do we still need to know before starting? ( 28850746 )
2017
39
Cardio-metabolic Risk Profile in Women with Previous History of Pre-Eclampsia. ( 29313572 )
2017
40
Hypertension: A new genetic clue to unravel the origins of pre-eclampsia. ( 28869250 )
2017
41
Elevated microRNA-520g in pre-eclampsia inhibits migration and invasion of trophoblasts. ( 28292471 )
2017
42
A study on clinicoradiological characteristics and pregnancy outcomes of reversible posterior leukoencephalopathy syndrome in preeclampsia or eclampsia. ( 28878299 )
2017
43
Isolated sixth Cranial Nerve Palsy in a Case Of Severe Pre-Eclampsia Presenting as Postpartum Diplopia. ( 28969214 )
2017
44
Validation of fullPIERS model for prediction of adverse outcomes among women with severe pre-eclampsia. ( 28475234 )
2017
45
Liver disease late in pregnancy without pre-eclampsia. ( 29364098 )
2017
46
Evaluation of the predictive value of placental vascularisation indices derived from 3-Dimensional power Doppler whole placental volume scanning for prediction of pre-eclampsia: A systematic review and meta-analysis. ( 28089506 )
2017
47
Long-term Risk of a Seizure Disorder After Eclampsia. ( 29112665 )
2017
48
The effects of sildenafil citrate on uterine angiogenic status and serum inflammatory markers in an L-NAME rat model of pre-eclampsia. ( 27940055 )
2017
49
Validation of Fetal Medicine Foundation algorithm for prediction of pre-eclampsia in the first trimester in an unselected Brazilian population. ( 28889785 )
2017
50
Determinants of magnesium sulphate use in women hospitalized at <29 weeks with severe or non-severe pre-eclampsia. ( 29272274 )
2017

Variations for Eclampsia

Expression for Eclampsia

Search GEO for disease gene expression data for Eclampsia.

Pathways for Eclampsia

Pathways related to Eclampsia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.16 FLT1 PGF
2 9.8 EPHX1 F2

GO Terms for Eclampsia

Cellular components related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALB CORIN EDN1 F2 FLT1 HLA-G
2 extracellular space GO:0005615 9.36 ALB EDN1 ENG F2 FLT1 INHBB

Biological processes related to Eclampsia according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.85 EDN1 F2 FLT1 PGF STOX1
2 response to drug GO:0042493 9.8 EDN1 ENG MTHFR PGF
3 regulation of receptor activity GO:0010469 9.77 EDN1 F2 INHBB OXT PGF
4 negative regulation of blood coagulation GO:0030195 9.48 EDN1 THBD
5 positive regulation of renal sodium excretion GO:0035815 9.43 EDN1 OXT
6 negative regulation of fibrinolysis GO:0051918 9.4 F2 THBD
7 response to transforming growth factor beta GO:0071559 9.32 EDN1 ENG
8 negative regulation of platelet activation GO:0010544 9.26 F2 THBD
9 positive regulation of prostaglandin secretion GO:0032308 9.16 EDN1 OXT
10 hemostasis GO:0007599 9.13 F2 SERPINC1 THBD
11 female pregnancy GO:0007565 9.02 CORIN OXT PGF TAC3 THBD

Molecular functions related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 EDN1 INHBB OXT

Sources for Eclampsia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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