MCID: ECL001
MIFTS: 51

Eclampsia

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Eclampsia

MalaCards integrated aliases for Eclampsia:

Name: Eclampsia 12 50 29 52 42 14 69
Eclampsia in Puerperium 12 69
Eclampsia, Postpartum 12
Postpartum Eclampsia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13593
ICD10 33 O15 O15.9 O15.2
MeSH 42 D004461
NCIt 47 C87167
UMLS 69 C0013537

Summaries for Eclampsia

Disease Ontology : 12 A pre-eclampsia characterized by the presence of seizures.

MalaCards based summary : Eclampsia, also known as eclampsia in puerperium, is related to pyelonephritis and preeclampsia/eclampsia 1, and has symptoms including seizures An important gene associated with Eclampsia is STOX1 (Storkhead Box 1), and among its related pathways/superpathways is Warfarin Pathway, Pharmacodynamics. The drugs Methyldopa and Remifentanil have been mentioned in the context of this disorder. Affiliated tissues include endothelial, placenta and testes, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 72 Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is a... more...

Related Diseases for Eclampsia

Diseases in the Eclampsia family:

Pre-Eclampsia Severe Pre-Eclampsia

Diseases related to Eclampsia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 200)
id Related Disease Score Top Affiliating Genes
1 pyelonephritis 28.5 EDN1 F2 SERPINC1
2 preeclampsia/eclampsia 1 28.5 CORIN EDN1 ENG EPHX1 FLT1 HLA-G
3 myocardial infarction 26.7 ALB EDN1 F2 MTHFR PGF SERPINC1
4 pre-eclampsia 12.4
5 severe pre-eclampsia 12.4
6 mild pre-eclampsia 12.2
7 preeclampsia/eclampsia 5 12.1
8 preeclampsia/eclampsia 4 12.1
9 preeclampsia/eclampsia 2 11.8
10 preeclampsia/eclampsia 3 11.8
11 hellp syndrome 11.4
12 gestational diabetes 11.1
13 chorea gravidarum 10.8
14 salivary gland adenoid cystic carcinoma 10.7 ENG FLT1
15 sydenham chorea 10.7 ENG FLT1 PGF
16 non-hodgkin lymphoma, during pregnancy 10.6 ALB F2
17 porphyria 10.6 F2 MTHFR
18 lockwood feingold syndrome 10.6 F2 MTHFR
19 pregnancy loss, recurrent 1 10.5 HLA-G MTHFR
20 hidradenoma 10.5 F2 FLT1 PGF
21 vernal conjunctivitis 10.4 ALB FLT1 MTHFR
22 citrullinemia, adult-onset type ii 10.4 ALB FLT1 PGF
23 endotheliitis 10.4
24 oral cavity carcinoma in situ 10.4 ALB F2
25 pyloric stenosis 10.3 F2 OXT
26 mediastinum leiomyoma 10.3 ALB F2 MTHFR
27 breast disease 10.3 MTHFR OXT PGF
28 female infertility of uterine origin 10.2 ALB F2
29 encephalopathy 10.1
30 hypoxia 10.1
31 cerebritis 10.1
32 myopia 10.1 ALB EDN1 F2
33 cortical blindness 10.1
34 pancreatic cystadenocarcinoma 10.0 ALB F2
35 pyelitis 10.0 ALB F2 OXT
36 paranasal sinus sarcoma 10.0 ALB EDN1 F2
37 retinitis 10.0
38 pyridoxine deficiency anemia 10.0 F2 SERPINC1
39 bubonic plague 10.0 ALB EDN1 F2
40 myiasis 9.9 F2 SERPINC1
41 placental abruption 9.9
42 testicular gonadoblastoma 9.9 F2 SERPINC1
43 syncope 9.9 F2 MTHFR SERPINC1
44 superior limbic keratoconjunctivitis 9.9 F2 MTHFR SERPINC1
45 follicular adenoma 9.9 F2 MTHFR SERPINC1
46 hiv-1 9.9 F2 MTHFR SERPINC1
47 rheumatoid lung disease 9.9 F2 MTHFR SERPINC1
48 thrombophilia 9.9
49 retinal detachment 9.9
50 placental insufficiency 9.9

Graphical network of the top 20 diseases related to Eclampsia:



Diseases related to Eclampsia

Symptoms & Phenotypes for Eclampsia

UMLS symptoms related to Eclampsia:


seizures

MGI Mouse Phenotypes related to Eclampsia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.96 CORIN EDN1 ENG F2 FLT1 NOSTRIN
2 homeostasis/metabolism MP:0005376 9.83 FLT1 HLA-G INHBB MTHFR OXT PGF
3 digestive/alimentary MP:0005381 9.76 ALB EDN1 ENG F2 INHBB OXT
4 integument MP:0010771 9.23 F2 INHBB MTHFR OXT PGF THBD

Drugs & Therapeutics for Eclampsia

Drugs for Eclampsia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 351)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyldopa Approved Phase 4,Phase 2,Phase 1 555-30-6 38853
2
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
3
Selenium Approved, Vet_approved Phase 4,Phase 2,Phase 3 7782-49-2
4
Metformin Approved Phase 4,Phase 3 657-24-9 14219 4091
5
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
6
Dalteparin Approved Phase 4,Phase 2,Phase 3 9005-49-6
7
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 772 46507594
8
Zinc Approved Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
9
Ephedrine Approved Phase 4,Phase 3 299-42-3 9294
10
Oxymetazoline Approved Phase 4 1491-59-4 4636
11
Phenylephrine Approved Phase 4 59-42-7 6041
12
Pseudoephedrine Approved Phase 4,Phase 3 90-82-4 7028
13
Labetalol Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 36894-69-6 3869
14
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7487-88-9 24083
15
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
16
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
17
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
18
Levobupivacaine Approved Phase 4 27262-47-1 92253
19
Captopril Approved Phase 4 62571-86-2 44093
20
Clonidine Approved Phase 4,Phase 1,Phase 2 4205-90-7 2803
21
Insulin Aspart Approved Phase 4 116094-23-6 16132418
22
Insulin Lispro Approved Phase 4 133107-64-9
23
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
24
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
25
Nifedipine Approved Phase 4,Phase 1,Phase 2,Early Phase 1 21829-25-4 4485
26
Calcium Carbonate Approved Phase 4 471-34-1
27
Thrombin Approved Phase 4
28
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
29
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
30
Desogestrel Approved Phase 4 54024-22-5 40973
31
Etonogestrel Approved, Investigational Phase 4 54048-10-1 40976 6917715
32
Amlodipine Approved Phase 4 88150-42-9 2162
33
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1 59-30-3 6037
34
leucovorin Approved, Nutraceutical Phase 4,Phase 3 58-05-9 143 6006
35
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2 67-97-0 6221 10883523 5280795
36
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2 50-14-6 5280793
37
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 1406-16-2
38 tannic acid Approved, Nutraceutical Phase 4,Phase 3
39 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1
42 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Phase 1
43 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2,Phase 1
44 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
45 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
47 Sympatholytics Phase 4,Phase 2,Phase 1,Early Phase 1
48 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
49 Analgesics, Opioid Phase 4,Phase 3,Phase 2
50 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 425)

id Name Status NCT ID Phase Drugs
1 Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape) Unknown status NCT01361425 Phase 4 methildopa;placebo
2 Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia Unknown status NCT00117546 Phase 4 alpha methyldopa
3 Remifentanil for General Anesthesia in Preeclamptics Unknown status NCT00567957 Phase 4 Remifentanil;Saline
4 Selenium Supplementation in Pregnancy Unknown status NCT01465867 Phase 4
5 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
6 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers Completed NCT01729468 Phase 4 Aspirin;Placebo
7 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients Completed NCT01972659 Phase 4 placebo;Magnesium Sulphate;sugammadex
8 Diuretics for Postpartum High Blood Pressure in Preeclampsia Completed NCT02163655 Phase 4 FUROSEMIDE;Placebo
9 Treatment Approaches to Preeclampsia Completed NCT01030627 Phase 4
10 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia Completed NCT01352234 Phase 4 Acetylsalicylic Acid;Acetylsalicylic Acid
11 Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies Completed NCT01608347 Phase 4 LMWH+Folic acid;Folic Acid
12 Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia Completed NCT02699827 Phase 4 Levobupivacaine hydrochloride;Magnesium sulphate;Saline 0.9%
13 A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen Completed NCT02091401 Phase 4 Magnesium Sulfate
14 Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia Completed NCT01408979 Phase 4 Magnesium sulfate 12 hours;Magnesium sulfate 24 hours
15 A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia Completed NCT00403572 Phase 4
16 Hemodynamic Measurements in Women With Serious Preeclampsia Completed NCT00199810 Phase 4
17 Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure Completed NCT01761916 Phase 4 CLONIDINE;CAPTOPRIL
18 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
19 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
20 Phenylephrine Versus Ephedrine in Pre-eclampsia Recruiting NCT02025426 Phase 4 Phenylephrine;Ephedrine
21 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Recruiting NCT03164304 Phase 4 Magnesium Sulfate
22 Impact of Antichlamydial Treatment on the Rate of Preeclampsia Recruiting NCT03233880 Phase 4 Azithromycin 1gm
23 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy Recruiting NCT02891174 Phase 4 Ibuprofen;Acetaminophen
24 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Recruiting NCT02911701 Phase 4 Acetaminophen;Ibuprofen
25 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
26 Low Dose Calcium to Prevent Preeclampsia Recruiting NCT02338687 Phase 4
27 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Recruiting NCT02920593 Phase 4 Vitamin D3
28 Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy Recruiting NCT01912677 Phase 4 Nifedipine;Labetalol;Methyldopa
29 Contraception in Women With Sickle Cell Disease Active, not recruiting NCT02594462 Phase 4 etonogestrel-releasing implant contraceptive
30 Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation Active, not recruiting NCT02353806 Phase 4 Amlodipine besylate
31 Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients Not yet recruiting NCT03237000 Phase 4 MgSO4
32 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
33 LMWH to Prevent Preeclampsia and Fetal Growth Restriction Terminated NCT00260520 Phase 4 Dalteparin
34 Atenativ Effect on Uterine Blood Flow and Preeclampsia Withdrawn NCT02278575 Phase 4 Atenativ
35 Investigating the Novel Observation of Right-Left Difference in Uterine Artery Vascular Resistance in Pre-Eclampsia Unknown status NCT00848679 Phase 3 Epidural lidocaine;Epidural lidocaine 2%
36 Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine Unknown status NCT00409253 Phase 3 URAPIDIL (EUPRESSYL*);NICARDIPINE
37 Randomized Clinical Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. Unknown status NCT02050529 Phase 2, Phase 3 Labetalol;Hydralazine
38 Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia Unknown status NCT01382732 Phase 3 Carbetocin;Oxytocin
39 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
40 Low Dose Aspirin for the Prevention of Preeclampsia Unknown status NCT01890005 Phase 3 Aspirin;Placebo
41 PP13 and Doppler Study to Predict Preeclampsia Unknown status NCT00928213 Phase 2, Phase 3 Progesterone;Low molecular weight Heparin;No Drug
42 Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases Unknown status NCT00872365 Phase 2, Phase 3
43 Folic Acid Dosage and Malformations Reduction Unknown status NCT01244347 Phase 3 folic acid;folic acid
44 New Magnesium Sulphate Protocol for Pre-eclampsia Completed NCT01846156 Phase 3 MgSO4
45 Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction Completed NCT00197340 Phase 3 Epidural ropivacaine
46 Magnesium Sulfate in Pregnancy and Postpartum Completed NCT02317146 Phase 2, Phase 3 Magnesium Sulfate
47 Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia Completed NCT01988298 Phase 2, Phase 3 Ibuprofen;Acetaminophen
48 L-Arginine in Pre-Eclampsia Completed NCT00157521 Phase 3 L-arginine
49 Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention Completed NCT02301780 Phase 3 Aspirin;Placebo
50 Induction With Foley OR Misoprostol (INFORM) Study Completed NCT01801410 Phase 3 Misoprostol

Search NIH Clinical Center for Eclampsia

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: eclampsia

Genetic Tests for Eclampsia

Genetic tests related to Eclampsia:

id Genetic test Affiliating Genes
1 Eclampsia 29

Anatomical Context for Eclampsia

MalaCards organs/tissues related to Eclampsia:

39
Endothelial, Placenta, Testes, Kidney, Liver, Heart, Brain

Publications for Eclampsia

Articles related to Eclampsia:

(show top 50) (show all 1685)
id Title Authors Year
1
Pre-eclampsia: Molecular events to biomarkers. ( 28924318 )
2017
2
Pre-eclampsia is primarily a placental disorder: FOR: Pre-eclampsia is primarily a placental disorder. ( 28921791 )
2017
3
Preterm pre-eclampsia: What every neonatologist should know. ( 28917582 )
2017
4
Peripapillary retinal nerve fiber layer thickness in preeclampsia and eclampsia. ( 28942577 )
2017
5
Shared biomarkers between female diastolic heart failure and pre-eclampsia: a systematic review and meta-analysis. ( 28451444 )
2017
6
The altered PD-1/PD-L1 pathway delivers the 'one-two punch' effects to promote the Treg/Th17 imbalance in pre-eclampsia. ( 28890543 )
2017
7
Catechol-O-methyltransferase Gene Polymorphism (Val158Met) and Development of Pre-eclampsia. ( 28625321 )
2017
8
Cardiac diastolic function after recovery from pre-eclampsia. ( 28906533 )
2017
9
A randomised controlled trial of consumption of dark chocolate in pregnancy to reduce pre-eclampsia: Difficulties in recruitment, allocation and adherence. ( 28913824 )
2017
10
Levels of serum-circulating angiogenic factors within 1 week prior to delivery are closely related to conditions of pregnant women with pre-eclampsia, gestational hypertension, and/or fetal growth restriction. ( 28929598 )
2017
11
Re: Pre-eclampsia: an important risk factor for asymptomatic heart failure. C. Ghossein-Doha, J. van Neer, B. Wissink, N. Breetveld, L. J. de Windt, A. P. J. van Dijk, M. J. van der Vlugt, M. C. H. Janssen, W. M. Heidema, R. R. Scholten and M. E. A. Spaanderman. Ultrasound Obstet Gynecol 2017; 49: 143-149. ( 28058791 )
2017
12
Re: Lung and cardiac ultrasound for hemodynamic monitoring of patients with severe pre-eclampsia. J. Ambrozic, G. Brzan Simenc, K. Prokselj, N. Tulz, M. Cvijic and M. Lucovnik. Ultrasound Obstet Gynecol 2017; 49: 104-109. ( 28058788 )
2017
13
Evaluation of Placental mir-155-5p and Long Non-coding RNA sONE Expression in Patients with Severe Pre-eclampsia. ( 28868266 )
2017
14
Determinants of pre-eclampsia/Eclampsia among women attending delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: a case control study. ( 28915802 )
2017
15
Re: Serious maternal complications in relation to severe pre-eclampsia: a retrospective cohort study of the impact of hospital volume; Severe maternal morbidity requires regionalisation of obstetric critical care; Guilt, blame and litigation: can an overenthusiastic 'safety culture' cause harm?: Maternal mortality: the heavy psychological burden on centre obstetricians. ( 28670731 )
2017
16
Validation of fullPIERS model for prediction of adverse outcomes among women with severe pre-eclampsia. ( 28475234 )
2017
17
Evaluation of the predictive value of placental vascularisation indices derived from 3-Dimensional power Doppler whole placental volume scanning for prediction of pre-eclampsia: A systematic review and meta-analysis. ( 28089506 )
2017
18
Screening for pre-eclampsia in the first trimester: what do we still need to know before starting? ( 28850746 )
2017
19
Response to: Using Carbon Monoxide Releasing Molecules in Models of Pre-Eclampsia: When Should We Be Monitoring Vascular Effects? ( 28911026 )
2017
20
Maternal bradycardia occurring prior to onset of HELLP syndrome in a woman with pre-eclampsia. ( 28501825 )
2017
21
Re: Endothelial dysfunction and vascular stiffness in women with previous pregnancy complicated by early or late pre-eclampsia. R. Orabona, E. Sciatti, E. Vizzardi, I. Bonadei and A. Valcamonico. Ultrasound Obstet Gynecol 2017; 49: 116-123. ( 28058790 )
2017
22
Comment on: Maternal pre-eclampsia as a risk factor for necrotizing enterocolitis. ( 28911253 )
2017
23
Association between interleukin-4 polymorphisms and risk of pre-eclampsia in a population of Chinese pregnant women. ( 28387873 )
2017
24
Severe pre-eclampsia before 26A weeks of gestation: how should we counsel women? ( 28229528 )
2017
25
Pre-eclampsia is primarily a placental disorder: AGAINST: Pre-eclampsia: the heart matters. ( 28921798 )
2017
26
Lung and cardiac ultrasound for hemodynamic monitoring of patients with severe pre-eclampsia. ( 27736042 )
2017
27
Pre-eclampsia: Screening and aspirin therapy for prevention of pre-eclampsia. ( 28869248 )
2017
28
Treatment using tadalafil for severe pre-eclampsia with fetal growth restriction. ( 28503744 )
2017
29
Assessment of quality of care among in-patients with postpartum haemorrhage and severe pre-eclampsia at st. Francis hospital nsambya: a criteria-based audit. ( 28086822 )
2017
30
A study on clinicoradiological characteristics and pregnancy outcomes of reversible posterior leukoencephalopathy syndrome in preeclampsia or eclampsia. ( 28878299 )
2017
31
Circulating adipokines are associated with pre-eclampsia in women with type 1 diabetes. ( 28875223 )
2017
32
Hypertension: A new genetic clue to unravel the origins of pre-eclampsia. ( 28869250 )
2017
33
Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt-1)/PlGF ratio, comparison of predictive accuracy for pre-eclampsia, and relation to uterine artery Doppler and response to aspirin. ( 28851242 )
2017
34
Historical evolution of ideas on eclampsia/preeclampsia: A proposed optimistic view of preeclampsia. ( 28941881 )
2017
35
Validation of Fetal Medicine Foundation algorithm for prediction of pre-eclampsia in the first trimester in an unselected Brazilian population. ( 28889785 )
2017
36
Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia. ( 27746364 )
2017
37
Prediction of severe pre-eclampsia by a combination of sFlt-1, CT-pro ET1 and blood pressure: exploratory study. ( 28643875 )
2017
38
Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study. ( 28726273 )
2017
39
MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. ( 28700503 )
2017
40
Accuracy of competing risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. ( 28067011 )
2017
41
Introduction of management protocol for early-onset severe pre-eclampsia. ( 28150368 )
2017
42
The effects of sildenafil citrate on uterine angiogenic status and serum inflammatory markers in an L-NAME rat model of pre-eclampsia. ( 27940055 )
2017
43
Serious Visual (Ocular) Complications in Pre-eclampsia and Eclampsia. ( 28867885 )
2017
44
Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion. ( 28232601 )
2017
45
What are the metabolic precursors which increase the risk of pre-eclampsia and how could these be investigated further. ( 28855067 )
2017
46
Toward a better understanding of the oocyte donation/pre-eclampsia connection. ( 27140289 )
2016
47
Expression of the complement system's activation factors in plasma of patients with early/late-onset severe pre-eclampsia. ( 27461873 )
2016
48
Prospective assessment of neurodevelopment in children following a pregnancy complicated by severe pre-eclampsia. ( 27388354 )
2016
49
A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50. ( 27181993 )
2016
50
Maternal Circulating microRNAs and Pre-Eclampsia: Challenges for Diagnostic Potential. ( 27638415 )
2016

Variations for Eclampsia

Expression for Eclampsia

Search GEO for disease gene expression data for Eclampsia.

Pathways for Eclampsia

Pathways related to Eclampsia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 9.8 EPHX1 F2

GO Terms for Eclampsia

Cellular components related to Eclampsia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 ALB CORIN EDN1 F2 FLT1 INHBB
2 extracellular space GO:0005615 9.36 ALB EDN1 ENG F2 FLT1 INHBB

Biological processes related to Eclampsia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.85 EDN1 F2 FLT1 PGF STOX1
2 negative regulation of blood coagulation GO:0030195 9.43 EDN1 THBD
3 positive regulation of renal sodium excretion GO:0035815 9.4 EDN1 OXT
4 negative regulation of fibrinolysis GO:0051918 9.37 F2 THBD
5 response to transforming growth factor beta GO:0071559 9.32 EDN1 ENG
6 negative regulation of platelet activation GO:0010544 9.26 F2 THBD
7 positive regulation of prostaglandin secretion GO:0032308 9.16 EDN1 OXT
8 hemostasis GO:0007599 9.13 F2 SERPINC1 THBD
9 female pregnancy GO:0007565 9.02 CORIN OXT PGF TAC3 THBD

Molecular functions related to Eclampsia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 EDN1 INHBB OXT

Sources for Eclampsia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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