Aliases & Classifications for Ectopic Thymus

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Aliases & Descriptions for Ectopic Thymus:

Name: Ectopic Thymus 10 12 65


Classifications:



External Ids:

Disease Ontology10 DOID:6307
NCIt42 C27804

Summaries for Ectopic Thymus

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Wikipedia:68 Ectopic thymus is a condition where thymus tissue is found in an abnormal location. more...

MalaCards based summary: Ectopic Thymus is related to thymoma and cavernous hemangioma. An important gene associated with Ectopic Thymus is TFAP2A (Transcription Factor AP-2 Alpha (Activating Enhancer Binding Protein 2 Alpha)), and among its related pathways are Thyroxine (Thyroid Hormone) Production and Hormone ligand-binding receptors. Affiliated tissues include thymus and thyroid, and related mouse phenotypes are normal and hematopoietic system.

Related Diseases for Ectopic Thymus

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Diseases related to Ectopic Thymus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1thymoma30.4CALCA, CD5, NKX2-1, SYP
2cavernous hemangioma30.3CD99, CHGA, SYP
3cervicitis10.6
4thyroiditis10.3
5endometrial stromal sarcoma10.3CHGA, SYP
6flat retinoschisis10.3CHGA, SYP
7thymus squamous cell carcinoma10.3FOXN1, SYP, TFAP2A
8ureter small cell carcinoma10.3CHGA, SYP
9third-degree atrioventricular block10.3CHGA, SYP
10solar retinopathy10.3CD4, CD8A
11urachus cancer10.3CD4, CD8A
12auditory system disease10.3CHGA, SYP
13paroxysmal nocturnal hemoglobinuria10.3CALCA, SYP
14cervix squamous papilloma10.3CD4, CD8A
15bladder leiomyoma10.3CD4, CD8A
16spinocerebellar ataxia10.3BCL2, CD5
17gallbladder endocrine tumor10.3CHGA, SYP
18bleeding diathesis due to integrin alpha2-beta1 deficiency10.3BCL2, CD5
19small cell neuroendocrine carcinoma10.3CD4, CR2
20peritoneum cancer10.3CHGA, SYP
21cutaneous ganglioneuroma10.3CD4, CD8A
22cervical incompetence10.3CHGA, SYP
23selective iga deficiency disease10.2CALCA, CHGA, SYP
24good syndrome10.2CD4, CD8A
25fallopian tube serous papilloma10.2NKX2-1, SYP
26waldeyer's ring cancer10.2CALCA, CHGA
27pulmonary valve disease10.2CALCA, CHGA, SYP
28eumycotic mycetoma10.2CALCA, NKX2-1, TSHR
29branchiooculofacial syndrome10.2
30carcinoid tumor childhood10.2CALCA, CHGA, SYP
31small cell lung cancer, childhood10.2CHGA, NKX2-1, SYP
32hemangiopericytoma10.2CHGA, NKX2-1, SYP
33ophthalmia neonatorum10.2CHGA, SYP
34lethal midline granuloma10.2CD4, CD5, CD8A
35food allergy10.2CALCA, NKX2-1, TSHR
36vulvar sebaceous carcinoma10.2CHGA, NKX2-1, SYP
37pulmonary embolism10.2CHGA, NKX2-1, SYP
38aggressive digital papillary adenocarcinoma10.2CALB2, CD5
39scoliosis10.2CHGA, NKX2-1, SYP
40ureteral disease10.2CHGA, NKX2-1, SYP
41epithelioid trophoblastic tumor10.2CD4, CD8A
42oral hairy leukoplakia10.2CHGA, NKX2-1, SYP
43thymus gland disease10.2CD4, CD5, CD8A
44anthrax disease10.2CD4, CD5, CD8A
45coronin-1a deficiency10.2CD4, CD5, CD8A
46lung combined type small cell carcinoma10.2CHGA, NKX2-1, SYP
47joint disorders10.2CALCA, CHGA, SYP
48pulmonary neuroendocrine tumor10.2CHGA, NKX2-1, SYP
49micropapillomatosis labialis10.2BCL2, DNTT
50silent myocardial infarction10.2CHGA, NKX2-1, SYP

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to ectopic thymus

Symptoms for Ectopic Thymus

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Drugs & Therapeutics for Ectopic Thymus

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Drugs for Ectopic Thymus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Octreotideapproved, investigationalPhase 1, Phase 219183150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
 
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Ocphyl
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide acetate
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatin
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
2RadiopharmaceuticalsPhase 1, Phase 2345
3Fluorodeoxyglucose F18Phase 1, Phase 2340
4DihydroxyphenylalaninePhase 1, Phase 2112

Interventional clinical trials:

idNameStatusNCT IDPhase
1New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing SyndromeRecruitingNCT00001849Phase 1, Phase 2

Search NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

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Anatomical Context for Ectopic Thymus

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MalaCards organs/tissues related to Ectopic Thymus:

33
Thymus, Thyroid

Animal Models for Ectopic Thymus or affiliated genes

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MGI Mouse Phenotypes related to Ectopic Thymus:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.1CALB2, CALCA, CD4, CD5, CD8A, DNTT
2MP:00053976.3ANPEP, BCL2, CD4, CD5, CD7, CD8A
3MP:00053876.0ANPEP, BCL2, CD4, CD5, CD7, CD8A

Publications for Ectopic Thymus

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Articles related to Ectopic Thymus:

(show all 35)
idTitleAuthorsYear
1
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. (26269296)
2015
2
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. (23354892)
2013
3
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. (23106675)
2012
4
Active ectopic thymus predicts poor outcome after thymectomy in class III myasthenia gravis. (22177829)
2012
5
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. (23248863)
2012
6
Sonographic appearance of intrathyroid ectopic thymus in children. (22362225)
2012
7
Ectopic thymus presenting as neck mass in a neonate: a case report. (21654604)
2011
8
Radiology quiz case 2. Ectopic thymus. (21339410)
2011
9
Clinical management of cervical ectopic thymus in children. (21843706)
2011
10
Vascularized tissue engineering mouse chamber model supports thymopoiesis of ectopic thymus tissue grafts. (19715386)
2010
11
Cervical ectopic thymus masquerading as metastatic thyroid papillary carcinoma. (20614729)
2010
12
Ectopic thymus presenting as a right-side cervical mass in an infant. (18839165)
2009
13
Inspiratory stridor and dysphagia in two newborn infants caused by ectopic thymus tissue. (19104836)
2009
14
Cervical ectopic thymus. (19177048)
2009
15
Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex. (19265501)
2009
16
Cervical ectopic thymus in a 9-month-old girl: diagnostic difficulties. (19641469)
2009
17
Solid cervical ectopic thymus in an infant. (19573646)
2009
18
Clear cell carcinoma originating from ectopic thymus. (19440827)
2009
19
Cervical ectopic thymus presenting as a painless neck mass in a child. (17966246)
2007
20
Images in pathology: micronodular epithelial hyperplasia in ectopic thymus. (16501838)
2006
21
Cervical ectopic thymus in an infant. (16397725)
2006
22
Ectopic thymus presenting as a subglottic mass: diagnostic and management dilemmas. (15763300)
2005
23
Cervical ectopic thymus: a case report and review of the literature. (12363426)
2002
24
Ectopic thymus presenting as neck mass. (12508495)
2002
25
The analogy in cell immunophenotype and parameters of cell cycle of ectopic thymus, normal thymus, and some acute lymphoblastic leukemia of T-phenotype. (12458329)
2002
26
Adult ectopic thymus adjacent to thyroid and parathyroid. (11371249)
2001
27
Ectopic thymus presenting as a submandibular swelling. (11474464)
2001
28
Ectopic thymus presenting as a solid submandibular neck mass in an infant: case report and review of literature. (10519705)
1999
29
Ectopic thymus presenting as a neck swelling in a newborn. (17341962)
1998
30
Malignant thymoma in an ectopic thymus: CT appearance. (1885808)
1991
31
Bilateral ectopic thymus gland tissue associated with the cleft lip and palate. (2748765)
1989
32
Ectopic thymus in the neck; a case report and review of the literature. (3676587)
1987
33
Ectopic thymus: presenting as neck mass. (6726580)
1984
34
Radiologic seminar CCVII: ectopic thymus. (7431388)
1980
35
Ectopic thymus of the neck--report of three examples in children. (1161677)
1975

Variations for Ectopic Thymus

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Expression for genes affiliated with Ectopic Thymus

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Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for genes affiliated with Ectopic Thymus

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Pathways related to Ectopic Thymus according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9CHGA, TSHR
29.9CHGA, TSHR
39.4ANPEP, BCL2, CD4
49.1ANPEP, CALCA, NKX2-1, SYP, TFAP2A
58.8CD4, CD8A, CD99, SPN
67.7ANPEP, CD4, CD5, CD7, CD8A, CR2

GO Terms for genes affiliated with Ectopic Thymus

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Cellular components related to Ectopic Thymus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:004210110.2CD4, CD8A
2terminal boutonGO:00431959.5CALB2, CALCA, SYP
3external side of plasma membraneGO:00098978.5ANPEP, CD4, CD5, CD8A, CR2, SPN

Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1T cell lineage commitmentGO:000236010.5BCL2, FOXN1
2lymphocyte homeostasisGO:000226010.5BCL2, FOXN1
3negative regulation of calcium ion transport into cytosolGO:001052310.3BCL2, CALCA
4defense response to Gram-negative bacteriumGO:005082910.1CALCA, CD4, CHGA
5B cell differentiationGO:003018310.0BCL2, CR2, TSHR
6T cell costimulationGO:00312959.9CD4, CD5, SPN
7viral entry into host cellGO:00467189.7ANPEP, CD4, CR2
8T cell activationGO:00421109.1CD4, CD7, CD8A
9immune responseGO:00069558.1CD4, CD7, CD8A, CR2, SPN

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transmembrane signaling receptor activityGO:00048889.4CD4, CD5, CR2, SPN
2virus receptor activityGO:00016189.1ANPEP, CD4, CR2
3receptor activityGO:00048728.4ANPEP, CD4, CD5, CD7, CR2

Sources for Ectopic Thymus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet