MCID: ECT003
MIFTS: 27

Ectopic Thymus

Categories: Immune diseases

Aliases & Classifications for Ectopic Thymus

MalaCards integrated aliases for Ectopic Thymus:

Name: Ectopic Thymus 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:6307
NCIt 46 C27804
UMLS 69 C1333375

Summaries for Ectopic Thymus

MalaCards based summary : Ectopic Thymus is related to cervicitis and thyroiditis. An important gene associated with Ectopic Thymus is TFAP2A (Transcription Factor AP-2 Alpha), and among its related pathways/superpathways are Apoptosis and Autophagy and Corticotropin-releasing hormone signaling pathway. Affiliated tissues include thymus and thyroid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 72 Ectopic thymus is a condition where thymus tissue is found in an abnormal... more...

Related Diseases for Ectopic Thymus

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to Ectopic Thymus

Symptoms & Phenotypes for Ectopic Thymus

GenomeRNAi Phenotypes related to Ectopic Thymus according to GeneCards Suite gene sharing:

25 (show all 21)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-106 9.66 BCL2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.66 BCL2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.66 BCL2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.66 TFAP2A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.66 TFAP2A
6 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.66 BCL2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.66 TFAP2A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.66 BCL2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-182 9.66 TFAP2A
10 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.66 BCL2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.66 BCL2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.66 TFAP2A
13 Increased shRNA abundance (Z-score > 2) GR00366-A-210 9.66 BCL2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.66 TFAP2A
15 Increased shRNA abundance (Z-score > 2) GR00366-A-37 9.66 BCL2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.66 TFAP2A
17 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.66 TFAP2A
18 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.66 BCL2 TFAP2A
19 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.66 BCL2
20 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.66 BCL2
21 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.66 BCL2

MGI Mouse Phenotypes related to Ectopic Thymus:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.46 BCL2 CD5 FOXN1 TFAP2A
2 hearing/vestibular/ear MP:0005377 9.43 BCL2 FOXN1 TFAP2A
3 normal MP:0002873 9.26 CD5 FOXN1 OMG TFAP2A
4 pigmentation MP:0001186 8.8 BCL2 FOXN1 TFAP2A

Drugs & Therapeutics for Ectopic Thymus

Search Clinical Trials , NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

Anatomical Context for Ectopic Thymus

MalaCards organs/tissues related to Ectopic Thymus:

38
Thymus, Thyroid

Publications for Ectopic Thymus

Articles related to Ectopic Thymus:

(show all 37)
# Title Authors Year
1
Intrathyroidal ectopic thymus in children: a sonographic survey. ( 28440352 )
2017
2
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. ( 26269296 )
2015
3
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. ( 23354892 )
2013
4
Active ectopic thymus predicts poor outcome after thymectomy in class III myasthenia gravis. ( 22177829 )
2012
5
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. ( 23248863 )
2012
6
Sonographic appearance of intrathyroid ectopic thymus in children. ( 22362225 )
2012
7
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. ( 23106675 )
2012
8
Radiology quiz case 2. Ectopic thymus. ( 21339410 )
2011
9
Clinical management of cervical ectopic thymus in children. ( 21843706 )
2011
10
Ectopic thymus presenting as neck mass in a neonate: a case report. ( 21654604 )
2011
11
Cervical ectopic thymus masquerading as metastatic thyroid papillary carcinoma. ( 20614729 )
2010
12
Vascularized tissue engineering mouse chamber model supports thymopoiesis of ectopic thymus tissue grafts. ( 19715386 )
2010
13
Cervical ectopic thymus. ( 19177048 )
2009
14
Cervical ectopic thymus in a 9-month-old girl: diagnostic difficulties. ( 19641469 )
2009
15
Clear cell carcinoma originating from ectopic thymus. ( 19440827 )
2009
16
Solid cervical ectopic thymus in an infant. ( 19573646 )
2009
17
Inspiratory stridor and dysphagia in two newborn infants caused by ectopic thymus tissue. ( 19104836 )
2009
18
Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex. ( 19265501 )
2009
19
Case of right-neck tumor that appears to be ectopic thymus. ( 27277227 )
2009
20
Ectopic thymus presenting as a right-side cervical mass in an infant. ( 18839165 )
2009
21
Cervical ectopic thymus presenting as a painless neck mass in a child. ( 17966246 )
2007
22
Cervical ectopic thymus in an infant. ( 16397725 )
2006
23
Images in pathology: micronodular epithelial hyperplasia in ectopic thymus. ( 16501838 )
2006
24
Ectopic thymus presenting as a subglottic mass: diagnostic and management dilemmas. ( 15763300 )
2005
25
Cervical ectopic thymus: a case report and review of the literature. ( 12363426 )
2002
26
Ectopic thymus presenting as neck mass. ( 12508495 )
2002
27
The analogy in cell immunophenotype and parameters of cell cycle of ectopic thymus, normal thymus, and some acute lymphoblastic leukemia of T-phenotype. ( 12458329 )
2002
28
Adult ectopic thymus adjacent to thyroid and parathyroid. ( 11371249 )
2001
29
Ectopic thymus presenting as a submandibular swelling. ( 11474464 )
2001
30
Ectopic thymus presenting as a solid submandibular neck mass in an infant: case report and review of literature. ( 10519705 )
1999
31
Ectopic thymus presenting as a neck swelling in a newborn. ( 17341962 )
1998
32
Malignant thymoma in an ectopic thymus: CT appearance. ( 1885808 )
1991
33
Bilateral ectopic thymus gland tissue associated with the cleft lip and palate. ( 2748765 )
1989
34
Ectopic thymus in the neck; a case report and review of the literature. ( 3676587 )
1987
35
Ectopic thymus: presenting as neck mass. ( 6726580 )
1984
36
Radiologic seminar CCVII: ectopic thymus. ( 7431388 )
1980
37
Ectopic thymus of the neck--report of three examples in children. ( 1161677 )
1975

Variations for Ectopic Thymus

Expression for Ectopic Thymus

Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for Ectopic Thymus

Pathways related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.22 BCL2 TFAP2A
2 10.59 BCL2 TFAP2A

GO Terms for Ectopic Thymus

Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.54 BCL2 CD5 FOXN1
2 axonogenesis GO:0007409 9.48 BCL2 OMG
3 animal organ morphogenesis GO:0009887 9.46 BCL2 FOXN1
4 kidney development GO:0001822 9.43 BCL2 TFAP2A
5 hemopoiesis GO:0030097 9.4 BCL2 FOXN1
6 thymus development GO:0048538 9.32 BCL2 FOXN1
7 T cell homeostasis GO:0043029 9.26 BCL2 FOXN1
8 negative regulation of reactive oxygen species metabolic process GO:2000378 9.16 BCL2 TFAP2A
9 lymphocyte homeostasis GO:0002260 8.96 BCL2 FOXN1
10 T cell lineage commitment GO:0002360 8.62 BCL2 FOXN1

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 8.8 BCL2 FOXN1 TFAP2A

Sources for Ectopic Thymus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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