Aliases & Classifications for Ectopic Thymus

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Aliases & Descriptions for Ectopic Thymus:

Name: Ectopic Thymus 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:6307
NCIt42 C27804
UMLS65 C1333375

Summaries for Ectopic Thymus

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Wikipedia:68 Ectopic thymus is a condition where thymus tissue is found in an abnormal location. more...

MalaCards based summary: Ectopic Thymus is related to paroxysmal nocturnal hemoglobinuria and ureter transitional cell carcinoma. An important gene associated with Ectopic Thymus is TFAP2A (Transcription Factor AP-2 Alpha), and among its related pathways are Hormone ligand-binding receptors and Thyroxine (Thyroid Hormone) Production. Affiliated tissues include thymus, t cells and bone, and related mouse phenotypes are normal and endocrine/exocrine gland.

Related Diseases for Ectopic Thymus

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Diseases related to Ectopic Thymus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 129)
idRelated DiseaseScoreTop Affiliating Genes
1paroxysmal nocturnal hemoglobinuria10.5CALCA, SYP
2ureter transitional cell carcinoma10.5CHGA, SYP
3gallbladder small cell carcinoma10.5CHGA, SYP
4dental pulp disease10.5FOXN1, OMG, TFAP2A
5pediculus humanus capitis infestation10.5CHGA, SYP
6childhood malignant hemangiopericytoma10.5CHGA, SYP
7oxyphilic adenoma10.5CHGA, SYP
8perineural angioma10.5CHGA, SYP
9middle cerebral artery infarction10.5CHGA, SYP
10anovulation10.5NKX2-1, SYP
11thoracic benign neoplasm10.5CHGA, SYP
12bleeding diathesis due to integrin alpha2-beta1 deficiency10.5BCL2, CD5
13urinary system disease10.5CHGA, SYP
14urethra adenocarcinoma10.4CHGA, SYP
15fallopian tube serous papilloma10.4NKX2-1, SYP
16parathyroid adenoma10.4CALCA, CHGA
17hepatorenal syndrome10.4CD5, CR2
18pituitary apoplexy10.4CD4, CD8A
19hyperhomocysteinemia10.4CD4, CD8A
20malignant cornea melanoma10.4CD4, CD8A
21acute cystitis10.4CD4, CD8A
22graphite pneumoconiosis10.4CHGA, SYP
23inflammatory breast carcinoma10.4CR2, NKX2-1
24perivascular epithelioid cell tumor10.4NKX2-1, TSHR
25lung abscess10.4CD4, CR2
26wheat allergy10.4CHGA, SYP
27scabies10.4CALCA, CHGA, SYP
28pancreatic cystadenoma10.4CHGA, SYP
29cd3epsilon deficiency10.4CD4, CD8A
30lung occult small cell carcinoma10.4CALCA, CHGA, SYP
31mycotic corneal ulcer10.4CD4, CD8A
32fallopian tube papillary adenocarcinoma10.4CALB2, CD5
33parenchymatous neurosyphilis10.4CALCA, NKX2-1, TSHR
34monkeypox10.4CD4, CD8A
35pinheiro freire-maia miranda syndrome10.4CHGA, SYP
36subungual glomus tumor10.4BCL2, DNTT
37eunuchism10.4CALCA, NKX2-1, TSHR
38peritoneal serous adenocarcinoma10.4CHGA, NKX2-1, SYP
39mediastinal osteogenic sarcoma10.3CALCA, NKX2-1, TSHR
40toxic maculopathy10.3CD4, CD8A
41coronin-1a deficiency10.3CD4, CD8A
42ureter leiomyoma10.3CHGA, NKX2-1, SYP
43cervical large cell neuroendocrine carcinoma10.3CHGA, NKX2-1, SYP
44pancreatic solid pseudopapillary carcinoma10.3CHGA, SYP
45melas syndrome10.3CHGA, NKX2-1, SYP
46corneal ectasia10.3CALCA, CHGA
47steroid inherited metabolic disorder10.3CALCA, CHGA, SYP
48thymus large cell carcinoma10.3CHGA, NKX2-1, SYP
49anal margin basal cell carcinoma10.3BCL2, DNTT
50papillary follicular thyroid adenocarcinoma10.3CHGA, NKX2-1, SYP

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to ectopic thymus

Symptoms for Ectopic Thymus

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Drugs & Therapeutics for Ectopic Thymus

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Drugs for Ectopic Thymus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Octreotideapproved, investigationalPhase 1, Phase 219883150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
 
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Ocphyl
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide acetate
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatin
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
2RadiopharmaceuticalsPhase 1, Phase 2362
3Fluorodeoxyglucose F18Phase 1, Phase 2356
4DihydroxyphenylalaninePhase 1, Phase 2123

Interventional clinical trials:

idNameStatusNCT IDPhase
1New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing SyndromeRecruitingNCT00001849Phase 1, Phase 2

Search NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

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Anatomical Context for Ectopic Thymus

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MalaCards organs/tissues related to Ectopic Thymus:

33
Thymus, T cells, Bone, Lung, Monocytes, Thalamus, Endothelial

Animal Models for Ectopic Thymus or affiliated genes

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MGI Mouse Phenotypes related to Ectopic Thymus:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028737.8CALB2, CD4, CD5, CD8A, DNTT, FOXN1
2MP:00053797.2ANPEP, BCL2, CD4, CD7, CD8A, CHGA
3MP:00053976.2ANPEP, BCL2, CD4, CD5, CD7, CD8A
4MP:00053875.9ANPEP, BCL2, CD4, CD5, CD7, CD8A

Publications for Ectopic Thymus

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Articles related to Ectopic Thymus:

(show all 35)
idTitleAuthorsYear
1
Newborn screening and diagnosis of mucopolysaccharidoses: application of tandem mass spectrometry. (25620850)
2014
2
Role of anatomical right hepatic trisectionectomy for perihilar cholangiocarcinoma. (24399779)
2014
3
Oral tacrolimus for pediatric steroid-resistant ulcerative colitis. (23582736)
2014
4
FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. (23960073)
2013
5
The epidemiology of polymyalgia rheumatica in primary care: a research protocol. (22703582)
2012
6
Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases. (22081483)
2012
7
A randomized, controlled clinical trial: the effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial. (22126115)
2011
8
Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress. (19879959)
2010
9
AGT*M235T polymorphism in acute ischemic cardiac dysfunction: the gisca project. (20549134)
2010
10
Invasive tubular carcinoma of the breast frequently is clonally related to flat epithelial atypia and low-grade ductal carcinoma in situ. (19675453)
2009
11
Excitatory and anti-oscillatory actions of nitric oxide in thalamus. (18535092)
2008
12
Inhibition of syndecan-1 expression and function in oral cancer cells. (19020713)
2008
13
Resistin- and Obesity-associated metabolic diseases. (17952831)
2007
14
Structure of human MIP-3alpha chemokine. (16820679)
2006
15
Tyrosine nitration on p65: a novel mechanism to rapidly inactivate nuclear factor-kappaB. (15657065)
2005
16
Alpha- and beta-tubulin expression in rectal cancer development. (16101133)
2005
17
Acute encephalitis, a poliomyelitis-like syndrome and neurological sequelae in a hamster model for flavivirus infections. (12946018)
2003
18
Subsite mapping of human salivary alpha-amylase and the mutant Y151M. (12782315)
2003
19
Analysis of a viridans group strain reveals a case of bacteremia due to lancefield group G alpha-hemolytic Streptococcus dysgalactiae subsp equisimilis in a patient with pyomyositis and reactive arthritis. (12574255)
2003
20
Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). (11756157)
2002
21
Complete inhibition of in vivo glioma growth by oncostatin M. (11238743)
2001
22
Asymmetric hydrogenation of enamides with Rh-BisP and Rh-miniPHOS catalysts. scope, limitations, and mechanism. (11457389)
2001
23
Portal vein thrombosis associated to prothrombin G20210A mutation and protein C deficiency. (10898280)
2000
24
Pseudomonas folliculitis from a spa pool in an immunocompromised patient. (10091900)
1999
25
Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms. (10565827)
1999
26
Soluble mannan and beta-glucan inhibit the uptake of Malassezia furfur by human monocytic cell line, THP-1. (9718212)
1998
27
CpG motif in DNA from immune complexes of SLE patients augments expression of intercellular adhesion molecule-1 on endothelial cells]. (8990929)
1996
28
Elevated serum CK-MB and CK-BB isoenzymes in a patient with small cell lung cancer: a case report. (7780887)
1995
29
Gastrinoma of the common bile duct: immunohistochemical and ultrastructural study of a case. (7665823)
1995
30
Surgical resection in patients with nonseminomatous germ cell tumor who fail to normalize serum tumor markers after chemotherapy. (7506856)
1994
31
Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities. (7852852)
1994
32
Preclinical studies for adoptive immunotherapy in bone marrow transplantation. Generation of anti-CD3 activated cytotoxic T cells from normal donors and autologous bone marrow transplant candidates. (8356589)
1993
33
Serial IgG and IgM serum levels after infusion of different Ig-preparations (IgG or IgM-enriched) in preterm infants. (8298714)
1993
34
Serum interleukin-6 and fever at diagnosis in children with acute leukemia. (8498648)
1993
35
A DBL-homologous region of the yeast CLS4/CDC24 gene product is important for Ca(2+)-modulated bud assembly. (1755844)
1991

Variations for Ectopic Thymus

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Expression for genes affiliated with Ectopic Thymus

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Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for genes affiliated with Ectopic Thymus

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GO Terms for genes affiliated with Ectopic Thymus

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Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1lymphocyte homeostasisGO:000226010.3BCL2, FOXN1
2T cell lineage commitmentGO:000236010.3BCL2, FOXN1
3negative regulation of reactive oxygen species metabolic processGO:200037810.2BCL2, TFAP2A
4activation of adenylate cyclase activityGO:000719010.0CALCA, TSHR
5organ morphogenesisGO:00098879.9BCL2, FOXN1, NKX2-1
6negative regulation of ossificationGO:00302799.8BCL2, CALCA
7defense response to Gram-negative bacteriumGO:00508299.7CALCA, CD4, CHGA
8T cell activationGO:00421108.7CD4, CD7, CD8A

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.8CD4, CD8A

Sources for Ectopic Thymus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet