Aliases & Classifications for Ectopic Thymus

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Aliases & Descriptions for Ectopic Thymus:

Name: Ectopic Thymus 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:6307
NCIt43 C27804

Summaries for Ectopic Thymus

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Wikipedia:69 Ectopic thymus is a condition where thymus tissue is found in an abnormal location. more...

MalaCards based summary: Ectopic Thymus is related to cervicitis and thyroiditis. An important gene associated with Ectopic Thymus is TFAP2A (Transcription Factor AP-2 Alpha), and among its related pathways are Apoptosis and Autophagy and Corticotropin-releasing hormone. Affiliated tissues include thymus and thyroid, and related mouse phenotypes are hearing/vestibular/ear and pigmentation.

Related Diseases for Ectopic Thymus

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Diseases related to Ectopic Thymus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis10.3
2thyroiditis10.0
3branchiooculofacial syndrome9.8
4hemangioma9.8
5leukemia9.8
6myasthenia gravis9.8
7lymphoblastic leukemia9.8
8papillary carcinoma9.8
9thymoma9.8
10cavernous hemangioma9.8
11cleft lip9.8
12dysphagia9.8
13stenosis of lacrimal sac9.5BCL2, SYP
14adult teratoma9.2BCL2, SYP
15testicular granulosa cell tumor8.4BCL2, FOXN1, OMG, TFAP2A
16clivus chondroid chordoma8.0BCL2, FOXN1, OMG, SYP, TFAP2A

Graphical network of diseases related to Ectopic Thymus:



Diseases related to ectopic thymus

Symptoms for Ectopic Thymus

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Drugs & Therapeutics for Ectopic Thymus

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Drugs for Ectopic Thymus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
OctreotidePhase 1, Phase 220683150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate

Interventional clinical trials:

idNameStatusNCT IDPhase
1New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing SyndromeRecruitingNCT00001849Phase 1, Phase 2

Search NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

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Anatomical Context for Ectopic Thymus

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MalaCards organs/tissues related to Ectopic Thymus:

34
Thymus, Thyroid

Animal Models for Ectopic Thymus or affiliated genes

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MGI Mouse Phenotypes related to Ectopic Thymus:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.2BCL2, FOXN1, TFAP2A
2MP:00011869.2BCL2, FOXN1, TFAP2A
3MP:00028738.5FOXN1, OMG, SYP, TFAP2A

Publications for Ectopic Thymus

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Articles related to Ectopic Thymus:

(show all 36)
idTitleAuthorsYear
1
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. (26269296)
2015
2
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. (23354892)
2013
3
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. (23106675)
2012
4
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. (23248863)
2012
5
Active ectopic thymus predicts poor outcome after thymectomy in class III myasthenia gravis. (22177829)
2012
6
Sonographic appearance of intrathyroid ectopic thymus in children. (22362225)
2012
7
Ectopic thymus presenting as neck mass in a neonate: a case report. (21654604)
2011
8
Radiology quiz case 2. Ectopic thymus. (21339410)
2011
9
Clinical management of cervical ectopic thymus in children. (21843706)
2011
10
Vascularized tissue engineering mouse chamber model supports thymopoiesis of ectopic thymus tissue grafts. (19715386)
2010
11
Cervical ectopic thymus masquerading as metastatic thyroid papillary carcinoma. (20614729)
2010
12
Ectopic thymus presenting as a right-side cervical mass in an infant. (18839165)
2009
13
Inspiratory stridor and dysphagia in two newborn infants caused by ectopic thymus tissue. (19104836)
2009
14
Case of right-neck tumor that appears to be ectopic thymus. (27277227)
2009
15
Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex. (19265501)
2009
16
Cervical ectopic thymus in a 9-month-old girl: diagnostic difficulties. (19641469)
2009
17
Clear cell carcinoma originating from ectopic thymus. (19440827)
2009
18
Cervical ectopic thymus. (19177048)
2009
19
Solid cervical ectopic thymus in an infant. (19573646)
2009
20
Cervical ectopic thymus presenting as a painless neck mass in a child. (17966246)
2007
21
Images in pathology: micronodular epithelial hyperplasia in ectopic thymus. (16501838)
2006
22
Cervical ectopic thymus in an infant. (16397725)
2006
23
Ectopic thymus presenting as a subglottic mass: diagnostic and management dilemmas. (15763300)
2005
24
The analogy in cell immunophenotype and parameters of cell cycle of ectopic thymus, normal thymus, and some acute lymphoblastic leukemia of T-phenotype. (12458329)
2002
25
Cervical ectopic thymus: a case report and review of the literature. (12363426)
2002
26
Ectopic thymus presenting as neck mass. (12508495)
2002
27
Adult ectopic thymus adjacent to thyroid and parathyroid. (11371249)
2001
28
Ectopic thymus presenting as a submandibular swelling. (11474464)
2001
29
Ectopic thymus presenting as a solid submandibular neck mass in an infant: case report and review of literature. (10519705)
1999
30
Ectopic thymus presenting as a neck swelling in a newborn. (17341962)
1998
31
Malignant thymoma in an ectopic thymus: CT appearance. (1885808)
1991
32
Bilateral ectopic thymus gland tissue associated with the cleft lip and palate. (2748765)
1989
33
Ectopic thymus in the neck; a case report and review of the literature. (3676587)
1987
34
Ectopic thymus: presenting as neck mass. (6726580)
1984
35
Radiologic seminar CCVII: ectopic thymus. (7431388)
1980
36
Ectopic thymus of the neck--report of three examples in children. (1161677)
1975

Variations for Ectopic Thymus

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Expression for genes affiliated with Ectopic Thymus

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Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for genes affiliated with Ectopic Thymus

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Pathways related to Ectopic Thymus according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2BCL2, TFAP2A
29.2BCL2, TFAP2A

GO Terms for genes affiliated with Ectopic Thymus

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Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1T cell lineage commitmentGO:00023609.7BCL2, FOXN1
2lymphocyte homeostasisGO:00022609.6BCL2, FOXN1
3negative regulation of reactive oxygen species metabolic processGO:20003789.6BCL2, TFAP2A
4T cell homeostasisGO:00430299.6BCL2, FOXN1
5cellular response to organic substanceGO:00713109.5BCL2, SYP
6thymus developmentGO:00485389.5BCL2, FOXN1
7kidney developmentGO:00018229.5BCL2, TFAP2A
8animal organ morphogenesisGO:00098879.4BCL2, FOXN1
9hemopoiesisGO:00300979.4BCL2, FOXN1
10regulation of gene expressionGO:00104689.1BCL2, FOXN1
11axonogenesisGO:00074099.0BCL2, OMG

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009819.7FOXN1, TFAP2A
2sequence-specific DNA bindingGO:00435658.7BCL2, FOXN1, TFAP2A

Sources for Ectopic Thymus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet