MCID: ECT005
MIFTS: 45

Ectropion malady

Eye diseases category

Summaries for Ectropion

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63Wikipedia, 32MalaCards
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Wikipedia:63 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards: Ectropion, also known as ectropion, unspecified, is related to lagophthalmos and alopecia. An important gene associated with Ectropion is TGM1 (transglutaminase 1). The compound heme have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and cervix, and related mouse phenotypes are liver/biliary system and integument.

Aliases & Classifications for Ectropion

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 56SNOMED-CT, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

ectropion 8 10 44
ectropion, unspecified 8
unspecified ectropion 8
ectropion of eyelid 8
everted margin 8
ectropion nos 8


External Ids:

Disease Ontology8 DOID:1570
ICD9CM27 374.1, 374.10
MeSH34 D004483
ICD1025 H02.1

Related Diseases for Ectropion

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17GeneCards, 18GeneDecks
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Diseases related to Ectropion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 142)
idRelated DiseaseScoreTop Affiliating Genes
1lagophthalmos30.3MBD5, LAX1
2alopecia29.7MBTPS2
3congenital ichthyosiform erythroderma29.7TGM1, ABCA12, ABHD5, CYP4F22
4cicatricial ectropion10.7
5entropion10.6
6glaucoma10.4
7senile ectropion10.4
8cervicitis10.4
9mechanical ectropion10.3
10senile entropion10.2
11facial paralysis10.2
12barber say syndrome10.2
13burns10.1
14spastic ectropion10.1
15vaginitis10.1
16ichthyosis alopecia eclabion ectropion mental retardation10.1
17blepharo-cheilo-odontic syndrome10.1
18ichthyosis - alopecia - eclabion - ectropion - intellectual deficit10.1
19neurofibromatosis10.0
20juvenile glaucoma10.0
21paralytic lagophthalmos10.0
22herpes zoster10.0
23basal cell carcinoma10.0
24hypertrichosis10.0
25ectropion inferior cleft lip and or palate10.0
26congenital ectropion uveae10.0
27ichthyosis vulgaris10.0TGM1
28keratosis follicularis spinulosa decalvans10.0SAT1
29keratosis follicularis10.0MBTPS2, SAT1
30harlequin type ichthyosis10.0ABCA12, TGM1
31neutral lipid storage disease10.0ABHD5, AADAC
32autosomal recessive congenital ichthyosis10.0ABCA12, CYP4F22, TGM1
33keratoconjunctivitis sicca10.0
34clear cell adenocarcinoma10.0
35cervical clear cell adenocarcinoma10.0
36pyoderma gangrenosum10.0
37sezary's disease10.0
38adenocarcinoma10.0
39cervical adenocarcinoma10.0
40corneal ulcer10.0
41keratoconjunctivitis10.0
42myasthenia gravis10.0
43papilloma10.0
44pyoderma10.0
45vaginal discharge10.0
46ichthyosis, autosomal recessive 4b10.0
47ichthyosis, congenital, autosomal recessive 110.0
48ichthyosis, congenital, autosomal recessive 210.0
49isolated congenital ectropion10.0
50cicatricial entropion9.8

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Clinical Features for Ectropion

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Drugs & Therapeutics for Ectropion

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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32MalaCards
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MalaCards organs/tissues related to Ectropion:

32
Skin, Eye, Cervix, Testes, Bone, Lung

Animal Models for Ectropion or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Ectropion:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.0ABHD5, NF1, UROS, MBD5, SAT1
2MP:00107717.2TGM1, MBD5, UROS, NF1, ABHD5, ABCA12
3MP:00053786.7SAT1, MBD5, UROS, NF1, ABHD5, ABCA12
4MP:00053766.5SAT1, MBD5, UROS, NF1, ABHD5, ABCA12

Publications for Ectropion

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50PubMed
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Articles related to Ectropion:

(show top 50)    (show all 380)
idTitleAuthorsYear
1
Use of hyaluronic acid gel in the management of cicatricial ectropion: results and complications. (24063354)
2013
2
Ectropion, entropion, trichiasis. (24172761)
2013
3
Cicatricial ectropion: a complication of topical 5-fluorouracil. (21872544)
2012
4
Tarsal ectropion repair and lower blepharoplasty: A case report and review of literature. (21764653)
2012
5
Reconstruction of lower eyelid retraction or ectropion using a paranasal flap. (22274802)
2012
6
Why does the corrective procedure of the ectropion work for repairing the entropion? (22777459)
2012
7
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. (21346670)
2011
8
A 5-year retrospective review of Asian ectropion: how does it compare to ectropion amongst non-Asians? (21468462)
2011
9
The histopathology of involutional ectropion and entropion. (20029486)
2009
10
Teaching NeuroImages: reversible ectropion in myasthenia gravis. (19841376)
2009
11
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. (18317150)
2008
12
Temporary ectropion therapy by adhesive taping: a case study. (18638420)
2008
13
Cicatricial ectropion: repair with myocutaneous flaps and canthopexy. (16970762)
2006
14
Severe cicatrical ectropion: repair with a large advancement flap and autologous fascia sling. (16876090)
2006
15
Acute idiopathic bilateral lower lid ectropion. (16921228)
2006
16
The V-Y advancement for lower eyelid defect in preventing ectropion. (16874241)
2006
17
Cicatricial ectropion due to herpes zoster ophthalmicus. (16679689)
2006
18
Non-cicatricial upper eyelid ectropion. (16113391)
2005
19
What's your diagnosis? Congenital iris ectropion syndrome associated with glaucoma. (15825741)
2005
20
Composite Z plasty for cicatricial ectropion of Tessier III cleft. (14704563)
2004
21
Cicatricial ectropion in progressive skin diseases. (12045921)
2001
22
Ectropion and entropion. (11148701)
2000
23
Orbicularis oculi myocutaneous flap in reconstruction of postburn lower eyelid ectropion. (10498368)
1999
24
Cornea and iris changes in congenital ectropion uvea after trabeculotomy. (9150525)
1997
25
Macrostomia, hypertelorism, atrophic skin, severe hypertrichosis without ectropion: milder form of Barber-Say Syndrome. (9415700)
1997
26
The management of ectropion using the tarsoconjunctival composite graft. (8554747)
1996
27
Tarsal eversion: a dramatic form of ectropion at birth. (8913635)
1996
28
Repair of anal stricture and mucosal ectropion with Y-V or pedicle flap anoplasty. (8328629)
1993
29
Reversible ectropion after long-term use of topical tretinoin on photodamaged skin. (1401316)
1992
30
Reversible lower eyelid ectropion associated with dipivefrin. (2021181)
1991
31
Pedicle flaps for cicatricial ectropion. (3248180)
1988
32
Efficacy of surgical treatment for paralytic ectropion. (3627716)
1987
33
Involutional ectropion: a review of the management. (3554087)
1987
34
The medial spindle procedure for involutional medial ectropion. (3904688)
1985
35
Treatment of cervical ectropion by cryosurgery: effect on cervical mucus characteristics. (3838091)
1985
36
Reconstruction of the horizontal palpebral aperture after failed ectropion surgery with temporal migration of punctum. (3940144)
1985
37
Is electrodiathermy coagulation (EDC) of cervical ectropion effective in the prevention of cervical carcinoma? (6723703)
1984
38
Tarsal ectropion from detachment of the lower eyelid retractors. (7072813)
1982
39
Cicatricial ectropion of the upper lid secondary to herpes zoster ophthalmicus. (6973306)
1981
40
Ectropion produced by eyeglass frames. (550804)
1979
41
Ectropion of the lower eyelid secondary to MA1ller's muscle-capsulopalpebral fascia detachment. (677207)
1978
42
The ins and outs of entropion and ectropion: part II. Congenital ectropion. (974867)
1976
43
Surgical correction of lagophthalmos, complicated by paralytic ectropion. (938787)
1976
44
Cicatricial ectropion associated with lamellar ichthyosis. (4567857)
1973
45
Surgical correction of ectropion of the anal canal. (5809977)
1969
46
A medical ectropion procedure. (5674808)
1968
47
Operative treatment of severe cicatrical ectropion. (5335241)
1967
48
A simple modification of the sling operation for paralytic ectropion. (5876291)
1965
49
THE WHEELER METHOD FOR CORRECTION OF CICATRICIAL ECTROPION. (14089393)
1964
50
Removal of orbital tumor through inferior route with Kuhnt-Szymanowski repair of ectropion. (18879666)
1948

Genetic Variations for Ectropion

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Expression for genes affiliated with Ectropion

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ectropion

Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Compounds for genes affiliated with Ectropion

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28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Ectropion according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1heme28 11 2411.5CYP4V2, CYP4F22, UROS

GO Terms for genes affiliated with Ectropion

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16Gene Ontology
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Biological processes related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:0314249.7TGM1, ABCA12
2positive regulation of triglyceride catabolic processGO:0108989.6AADAC, ABHD5

Molecular functions related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1monooxygenase activityGO:0044979.8CYP4V2, CYP4F22
2oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenGO:0167059.7CYP4V2, CYP4F22
3triglyceride lipase activityGO:0048069.6AADAC, ABHD5

Products for genes affiliated with Ectropion

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  • Antibodies
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Sources for Ectropion

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet