Aliases & Classifications for Ectropion

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Aliases & Descriptions for Ectropion:

Name: Ectropion 10 47 12 36
Ectropion of Eyelid 10
 
Everted Margin 10

Classifications:



External Ids:

Disease Ontology10 DOID:1570
ICD9CM29 374.1, 374.10
MeSH36 D004483
UMLS65 C0013592

Summaries for Ectropion

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Wikipedia:68 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards based summary: Ectropion, also known as ectropion of eyelid, is related to neu-laxova syndrome1 and ichthyosis, autosomal recessive 4b. An important gene associated with Ectropion is TGM1 (Transglutaminase 1), and among its related pathways are Glycine, serine and threonine metabolism and Amino acid synthesis and interconversion (transamination). Affiliated tissues include skin, breast and lung, and related mouse phenotypes are liver/biliary system and craniofacial.

Related Diseases for Ectropion

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Diseases related to Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 352)
idRelated DiseaseScoreTop Affiliating Genes
1neu-laxova syndrome131.0PHGDH, PSAT1
2ichthyosis, autosomal recessive 4b30.7ABCA12, TGM1
3spastic ectropion30.4ABCA12, DNAAF3, MBTPS2, NF1, PHGDH, PSAT1
4congenital ectropion uveae12.4
5senile ectropion12.3
6cicatricial ectropion12.3
7mechanical ectropion12.3
8ectropion inferior cleft lip and or palate12.3
9ichthyosis alopecia eclabion ectropion mental retardation12.2
10ichthyosis-alopecia-eclabion-ectropion-intellectual disability syndrome12.2
11isolated congenital ectropion12.2
12barber-say syndrome11.9
13blepharo-cheilo-odontic syndrome11.4
14jones hersh yusk syndrome11.2
15mandibulofacial dysostosis-macroblepharon-macrostomia syndrome11.2
16euryblepharon10.4
17philophthalmiasis10.3PHGDH, PSAT1
18leukemia10.3
19thyroiditis10.3
20lung cancer10.2
21ichthyosis, congenital, autosomal recessive 4a10.2
22ichthyosis, congenital, autosomal recessive 610.2
23ichthyosis, congenital, autosomal recessive 1010.2
24neu-laxova syndrome 210.2
25ichthyosis, congenital, autosomal recessive 810.2
26ichthyosis, congenital, autosomal recessive 1110.2
27ichthyosis, congenital, autosomal recessive 710.2
28ichthyosis, congenital, autosomal recessive 110.2
29ichthyosis, congenital, autosomal recessive 910.2
30ichthyosis, congenital, autosomal recessive 210.2
31ichthyosis, congenital, autosomal recessive 310.2
32ichthyosis, congenital, autosomal recessive 510.2
33keratosis follicularis spinulosa decalvans, x-linked10.2
34congenital ichthyosiform erythroderma10.2
35sezary's disease10.2
36psph deficiency10.2PHGDH, PSAT1
37lymphoma10.2
38cerebritis10.2
39endotheliitis10.2
40charcot-marie-tooth disease, x-linked dominant, 610.2MBTPS2, SAT1
41keratosis palmoplantaris adenocarcinoma of the colon10.2MBTPS2, SAT1
42bronchopneumonia10.2MBTPS2, SAT1
43arthritis10.1
44prostatitis10.1
45melanoma10.1
46neuronitis10.1
47hypertensive encephalopathy10.1MBTPS2, SAT1
48diabetic polyneuropathy10.1ABCA12, TGM1
49rheumatoid arthritis10.1
50hepatocellular carcinoma10.1

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Symptoms for Ectropion

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Drugs & Therapeutics for Ectropion

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Drugs for Ectropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Immunologic FactorsPhase 4, Phase 018483
2EmollientsPhase 3121
3Dermatologic AgentsPhase 34555
4
FluorouracilapprovedPhase 0168451-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
5Immunosuppressive AgentsPhase 010422
6AntimetabolitesPhase 09454
7Antimetabolites, AntineoplasticPhase 05770

Interventional clinical trials:

idNameStatusNCT IDPhase
1PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic SurgeryNot yet recruitingNCT02761083Phase 4
2Hyaluronic Acid Gels for Lower Lid RetractionWithdrawnNCT01838252Phase 4
3Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine CutaneousNot yet recruitingNCT01222000Phase 3
4Lacrimal Drainage Resistance StudyCompletedNCT01766232
5Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface SurgeriesNot yet recruitingNCT02638610
65-fluorouracil Versus Placebo in Periocular Full Thickness Skin GraftsNot yet recruitingNCT02705352Phase 0

Search NIH Clinical Center for Ectropion


Cochrane evidence based reviews: ectropion

Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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MalaCards organs/tissues related to Ectropion:

33
Skin, Breast, Lung, T cells, Liver, Heart, Neutrophil

Animal Models for Ectropion or affiliated genes

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MGI Mouse Phenotypes related to Ectropion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4DNAAF3, NF1, SAT1, TWIST2
2MP:00053828.2ABCA12, NF1, PSAT1, TWIST2
3MP:00053847.3ABCA12, DNAAF3, NF1, PHGDH, SAT1, TWIST2
4MP:00053786.6ABCA12, DNAAF3, NF1, PHGDH, PSAT1, SAT1

Publications for Ectropion

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Articles related to Ectropion:

(show top 50)    (show all 418)
idTitleAuthorsYear
1
Sedation using 5% lidocaine patches, midazolam and propofol in a combative, obese adolescent with severe autistic disorder undergoing brain magnetic resonance imaging: a case report. (25558344)
2014
2
Tumour necrosis factor receptor-75 and risk of COPD exacerbation in the azithromycin trial. (24136332)
2014
3
External auditory canal paraganglioma: an atypical presentation. (23020887)
2012
4
The ASB2I^ Ubiquitin-interacting motif is involved in its monoubiquitination. (22382022)
2012
5
Periodontal disease and type 2 diabetes mellitus: is the HMGB1-RAGE axis the missing link? (22800803)
2012
6
Risky alcohol use in adolescence: the role of genetics (DRD2, SLC6A4) and coping motives. (21244440)
2011
7
A novel KIF5B-ALK variant in nonsmall cell lung cancer. (21656749)
2011
8
Giant cell tumor of the pes anserine bursa (extra-articular pigmented villonodular bursitis): a case report and review of the literature. (21687595)
2011
9
The evolution of island gigantism and body size variation in tortoises and turtles. (21270022)
2011
10
Serum zinc levels are low in children with simple febrile seizures compared with those in children with epileptic seizures and controls. (22041469)
2011
11
Disseminated cutaneous, laryngeal, nasopharyngeal, and recurrent obstructive nasal rhinosporidiosis in an immunocompetent adult: a case report and review of literature. (21342167)
2011
12
The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. (19442735)
2009
13
Limbic encephalitis associated with systemic lupus erythematosus. (19850655)
2009
14
Biosynthesis, processing, and secretion of glial cell line-derived neurotrophic factor in astroglial cells. (19005738)
2009
15
Urinary calreticulin in the diagnosis of bladder urothelial carcinoma. (19389084)
2009
16
Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma. (19464431)
2009
17
Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. (18398104)
2008
18
Thrombin mediates the extraintestinal thrombosis associated with experimental colitis. (18772359)
2008
19
Analysis of alpha-fetoprotein mRNA level on the tumor cell hematogenous spread of patients with hepatocellular carcinoma undergoing orthotopic liver transplantation. (17275497)
2007
20
Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure. (16952784)
2006
21
Overexpression of ABIN-2, a negative regulator of NF-kappaB, delays liver regeneration in the ABIN-2 transgenic mice. (16480954)
2006
22
Expression of leptin receptor and suppressor of cytokine signaling-3 genes in adenohypophysis of normal-fed and fasted cows. (16100569)
2005
23
Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs. (15380029)
2004
24
Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. (15180991)
2004
25
Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer. (12668617)
2003
26
Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. (11858820)
2002
27
Role of tyrosine kinase signaling in estrogen-induced LDL receptor gene expression in HepG2 cells. (11880239)
2002
28
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung. (11235022)
2001
29
Pathogenesis of single right coronary artery and pulmonic stenosis in English Bulldogs. (11300591)
2001
30
Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes. (11297555)
2001
31
Cartilage and bone containing benign mesenchymoma of the thigh and popliteal fossa. (10894384)
2000
32
Akt-dependent antiapoptotic action of insulin is sensitive to farnesyltransferase inhibitor. (11027130)
2000
33
Cytotoxic T lymphocyte antigen 4 (CTLA-4) dimorphism in patients with systemic lupus erythematosus. (10609073)
1999
34
Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. (9747616)
1998
35
14-3-3 proteins in neuronal development and function. (9626666)
1998
36
Paediatric dermatology. Impetigo. (9735496)
1998
37
Long-term outcomes of therapeutic pelvic lymphadenectomy for stage I endometrial adenocarcinoma. (9740684)
1998
38
Determination of tumor-related factors of influence on the uptake of the monoclonal antibody 323/A3 in experimental human ovarian cancer. (9139849)
1997
39
Interleukin-6 stimulates neutrophil production of platelet-activating factor. (8613706)
1996
40
Genetic influence on the shaping of the human T-cell receptor repertoire: quantitative assessment by competitive polymerase chain reaction. (8711431)
1996
41
The differential release of eosinophil granule proteins. Studies on patients with acute bacterial and viral infections. (7584682)
1995
42
The Vannini-Rizzoli orthosis: a unique case of thoracic outlet syndrome. (8466429)
1993
43
Relapsing polychondritis. (3522446)
1986
44
Farmer's lung disease in Vermont. (375344)
1979
45
Drug-induced lupus erythematosus with in vivo lupus erythematosus cells in pleural fluid. (77754)
1978
46
Ocular cicatricial pemphigoid associated with practolol therapy. (773404)
1976
47
Surgical treatment of hereditary pancreatitis: report of a case. (4714086)
1973
48
An interesting case of partial anodontia. (18918912)
1947
49
50

Variations for Ectropion

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Expression for genes affiliated with Ectropion

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Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Pathways related to Ectropion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6PHGDH, PSAT1
2
Show member pathways
9.6PHGDH, PSAT1

GO Terms for genes affiliated with Ectropion

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Biological processes related to Ectropion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratinocyte differentiationGO:003021610.0ABCA12, TGM1
2spinal cord developmentGO:00215109.8NF1, PHGDH
3neural tube developmentGO:00219159.6NF1, PHGDH
4regulation of gene expressionGO:00104689.3NF1, PHGDH

Sources for Ectropion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet