MCID: ECT005
MIFTS: 45

Ectropion malady

Eye diseases category

Summaries for Ectropion

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63Wikipedia, 32MalaCards
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Wikipedia:63 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards: Ectropion, also known as ectropion, unspecified, is related to lagophthalmos and alopecia. An important gene associated with Ectropion is TGM1 (transglutaminase 1). The compound heme have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and cervix, and related mouse phenotypes are liver/biliary system and integument.

Aliases & Classifications for Ectropion

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 56SNOMED-CT, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

ectropion 8 10 44
ectropion, unspecified 8
unspecified ectropion 8
ectropion of eyelid 8
everted margin 8
ectropion nos 8


External Ids:

Disease Ontology8 DOID:1570
ICD9CM27 374.1, 374.10
MeSH34 D004483
ICD1025 H02.1

Related Diseases for Ectropion

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17GeneCards, 18GeneDecks
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Diseases related to Ectropion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 142)
idRelated DiseaseScoreTop Affiliating Genes
1lagophthalmos30.3MBD5, LAX1
2alopecia29.7MBTPS2
3congenital ichthyosiform erythroderma29.7TGM1, ABCA12, ABHD5, CYP4F22
4cicatricial ectropion10.7
5entropion10.6
6glaucoma10.4
7senile ectropion10.4
8cervicitis10.4
9mechanical ectropion10.3
10senile entropion10.2
11facial paralysis10.2
12barber say syndrome10.2
13burns10.1
14spastic ectropion10.1
15vaginitis10.1
16ichthyosis alopecia eclabion ectropion mental retardation10.1
17blepharo-cheilo-odontic syndrome10.1
18ichthyosis - alopecia - eclabion - ectropion - intellectual deficit10.1
19neurofibromatosis10.0
20juvenile glaucoma10.0
21paralytic lagophthalmos10.0
22herpes zoster10.0
23basal cell carcinoma10.0
24hypertrichosis10.0
25ectropion inferior cleft lip and or palate10.0
26congenital ectropion uveae10.0
27ichthyosis vulgaris10.0TGM1
28keratosis follicularis spinulosa decalvans10.0SAT1
29keratosis follicularis10.0MBTPS2, SAT1
30harlequin type ichthyosis10.0ABCA12, TGM1
31neutral lipid storage disease10.0ABHD5, AADAC
32autosomal recessive congenital ichthyosis10.0ABCA12, CYP4F22, TGM1
33keratoconjunctivitis sicca10.0
34clear cell adenocarcinoma10.0
35cervical clear cell adenocarcinoma10.0
36pyoderma gangrenosum10.0
37sezary's disease10.0
38adenocarcinoma10.0
39cervical adenocarcinoma10.0
40corneal ulcer10.0
41keratoconjunctivitis10.0
42myasthenia gravis10.0
43papilloma10.0
44pyoderma10.0
45vaginal discharge10.0
46ichthyosis, autosomal recessive 4b10.0
47ichthyosis, congenital, autosomal recessive 110.0
48ichthyosis, congenital, autosomal recessive 210.0
49isolated congenital ectropion10.0
50cicatricial entropion9.8

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Clinical Features for Ectropion

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Drugs & Therapeutics for Ectropion

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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32MalaCards
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MalaCards organs/tissues related to Ectropion:

32
Skin, Eye, Cervix, Bone, Lung, Testes

Animal Models for Ectropion or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Ectropion:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.0ABHD5, NF1, UROS, MBD5, SAT1
2MP:00107717.2TGM1, MBD5, UROS, NF1, ABHD5, ABCA12
3MP:00053786.7SAT1, MBD5, UROS, NF1, ABHD5, ABCA12
4MP:00053766.5SAT1, MBD5, UROS, NF1, ABHD5, ABCA12

Publications for Ectropion

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50PubMed
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Articles related to Ectropion:

(show top 50)    (show all 380)
idTitleAuthorsYear
1
Congenital ectropion uveae presenting as acute glaucoma in a 3-year-old child. (23397121)
2013
2
The effectiveness of a simultaneous medial spindle procedure for involutional punctal ectropion with lid laxity in patients who require endonasal dacryocystorhinostomy instead of external dacryocystorhinostomy to prevent pump failure. (23851759)
2013
3
Conjunctival bleeding after ectropion repair due to paraneoplastic primary fibrinolysis. (21743371)
2012
4
Congenital ectropion uvea and mechanisms of glaucoma in neurofibromatosis type 1: new insights. (22480745)
2012
5
Giant mass conjunctival rhinosporidiosis causing severe mechanical ectropion. (23360029)
2012
6
Ectropion. (20590414)
2010
7
Suspension suture canthopexy: a minimally invasive procedure for correcting mild to moderate ectropion. (19958433)
2009
8
Repair of cicatricial ectropion in a harlequin baby. (19683196)
2009
9
Acute erythema and edematous skin reaction and ectropion following docetaxel in a patient with non-small cell lung cancer. (18828046)
2008
10
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip. (16637845)
2006
11
Surgical management of cicatricial ectropion following scarring dermatopathies in two dogs. (16178849)
2005
12
Use of a suture anchor for correction of ectropion in facial paralysis. (15622256)
2005
13
Effectiveness and persistence of a topical treatment for cervical ectropion with deoxyribonucleic acid. (16170291)
2005
14
Surgical Pearl: Temporary suspension suture (Frost suture) to help prevent ectropion after infraorbital reconstruction. (14639392)
2003
15
Laser conjunctivoplasty: a new technique for correction of mild medial ectropion. (12868029)
2003
16
Progression of congenital ectropion uveae. (14557203)
2003
17
Rotation mattress suture: a powerful adjunct for ectropion correction. (14506429)
2003
18
Causes of involutional ectropion and entropion--age-related tarsal changes are the key. (10749160)
2000
19
Late-onset unilateral primary developmental glaucoma associated with iridotrabecular dysgenesis, congenital ectropion uveae and thickened corneal nerves: a new neural crest syndrome? (10929982)
1999
20
Paralytic ectropion: a complication of malar implant surgery. (9558664)
1998
21
Congenital iris ectropion associated with ocular albinism, foveal hypoplasia, and keratoconjunctivitis sicca. (10532783)
1997
22
Temporary ectropion due to topical fluorouracil. (8187543)
1994
23
Island flap anoplasty for anal canal stenosis and mucosal ectropion. (8116980)
1994
24
Treatment of paralytic ectropion with composite chondrocutaneous graft. (7857053)
1994
25
Ectropion caused by eyeglasses. (1575239)
1992
26
Postblepharoplasty ectropion. Prevention and management. (1892615)
1991
27
Medial palpebral tendon repair for medial ectropion of the lower eyelid. (1781834)
1991
28
Surgical correction of lower-eyelid tarsal ectropion by reinsertion of the retractors. (2003808)
1991
29
Medial palpebral tendon repair for medial ectropion of the lower eyelid. (2268597)
1990
30
Island flap anoplasty for the treatment of anal stricture and mucosal ectropion. (2361425)
1990
31
Carbon dioxide laser repair of medial ectropion. (3141859)
1988
32
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency. (3086578)
1986
33
The triangular island skin flap for treatment of anal ectropion. (6690262)
1984
34
Cicatricial ectropion secondary to herpes zoster. (6358990)
1983
35
McCord procedure for ectropion repair. (6342584)
1983
36
Surgical correction of ectropion in lamellar ichthyosis. (7051939)
1982
37
Complications of blepharoplasty. Orbital hematoma, ectropion, and scleral show. (7338009)
1981
38
A rare case of severe bilateral ectropion from scleroderma. (7015386)
1981
39
Combined Z-plasty and horizontal shortening procedure for ectropion. (6989255)
1980
40
Cutaneous surgery in the infraocular area and ectropion avoidance. (344001)
1978
41
Ectropion in an adolescent female: a case report. (966294)
1976
42
Repair of cicatricial ectropion by horizontal shortening and pedicle flap. (1097979)
1975
43
Cicatricial ectropion of the lower lid. (4596775)
1973
44
Method of correction of tarsal ectropion. (4936228)
1971
45
Persistent congenital ectropion of all four eyelids with megaloblepharon. (4236972)
1969
46
Cicatricial ectropion. (14041231)
1962
47
Cicatricial ectropion caused by cutaneous blastomycosis. (13507786)
1958
48
Lid abscess (Ghangan) as a cause of cicatricial ectropion and lagophthalmos. (13545316)
1958
49
CONGENITAL ECTROPION ASSOCIATED WITH BILATERAL PTOSIS-CASE REPORT. (18170058)
1944
50
Extensive Lupus of the Face of a Young Girl with Microstoma, Ectropion, and Early Malignant X-ray Papilloma. (19986338)
1928

Genetic Variations for Ectropion

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Expression for genes affiliated with Ectropion

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ectropion

Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Compounds for genes affiliated with Ectropion

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28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Ectropion according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1heme28 11 2411.5CYP4V2, CYP4F22, UROS

GO Terms for genes affiliated with Ectropion

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16Gene Ontology
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Biological processes related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:0314249.7TGM1, ABCA12
2positive regulation of triglyceride catabolic processGO:0108989.6AADAC, ABHD5

Molecular functions related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1monooxygenase activityGO:0044979.8CYP4V2, CYP4F22
2oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenGO:0167059.7CYP4V2, CYP4F22
3triglyceride lipase activityGO:0048069.6AADAC, ABHD5

Products for genes affiliated with Ectropion

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ectropion

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet