Aliases & Classifications for Ectropion

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Aliases & Descriptions for Ectropion:

Name: Ectropion 11 13 25 48 37
Ectropion of Eyelid 11
 
Everted Margin 11

Classifications:



External Ids:

Disease Ontology11 DOID:1570
ICD9CM30 374.1, 374.10
MeSH37 D004483

Summaries for Ectropion

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Wikipedia:69 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards based summary: Ectropion, also known as ectropion of eyelid, is related to neu-laxova syndrome1 and ichthyosis, autosomal recessive 4b. An important gene associated with Ectropion is ABCA12 (ATP Binding Cassette Subfamily A Member 12), and among its related pathways are Glycine, serine and threonine metabolism and Amino acid synthesis and interconversion (transamination). Affiliated tissues include skin, eye and cervix, and related mouse phenotypes are craniofacial and homeostasis/metabolism.

Related Diseases for Ectropion

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Diseases related to Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 138)
idRelated DiseaseScoreTop Affiliating Genes
1neu-laxova syndrome130.4PHGDH, PSAT1
2ichthyosis, autosomal recessive 4b29.9ABCA12, TGM1
3cicatricial ectropion12.1
4congenital ectropion uveae12.1
5senile ectropion12.1
6mechanical ectropion12.1
7spastic ectropion12.1
8ichthyosis with alopecia, eclabium, ectropion, and mental retardation11.9
9ichthyosis alopecia eclabion ectropion mental retardation11.8
10isolated congenital ectropion11.8
11barber-say syndrome11.7
12blepharocheilodontic syndrome11.5
13mandibulofacial dysostosis with macroblepharon and macrostomia10.9
14jones hersh yusk syndrome10.9
15euryblepharon10.4
16entropion10.4
17cervicitis10.2
18neutral lipid storage disease10.1PHGDH, PSAT1
19infertility10.1NF1, PHGDH
20burns10.0
21ptosis10.0
22lagophthalmos10.0
23facial paralysis10.0
24autism x-linked 410.0MBTPS2, SAT1
25ulerythema ophryogenesis10.0MBTPS2, SAT1
26ocular motility disease10.0ABCA12, TGM1
27juvenile spinal muscular atrophy9.9MBTPS2, SAT1
28senile entropion9.9
29vaginitis9.9
30intracranial hypertension9.9MBTPS2, SAT1
31uterine ligament clear cell adenocarcinoma9.9ABCA12, TGM1
32distichiasis9.9
33juvenile glaucoma9.9
34basal cell carcinoma9.9
35hypertrichosis9.9
36pyoderma9.9
37herpes zoster9.9
38pyoderma gangrenosum9.9
39neurofibromatosis9.9
40periostitis9.9
41ichthyosis vulgaris9.8ABCA12, TGM1
42ichthyosis, congenital, autosomal recessive 4a9.8
43ichthyosis, congenital, autosomal recessive 69.8
44ichthyosis, congenital, autosomal recessive 109.8
45neu-laxova syndrome 29.8
46ichthyosis, congenital, autosomal recessive 89.8
47ichthyosis, congenital, autosomal recessive 119.8
48ichthyosis, congenital, autosomal recessive 79.8
49ichthyosis, congenital, autosomal recessive 19.8
50ichthyosis, congenital, autosomal recessive 99.8

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Symptoms for Ectropion

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Drugs & Therapeutics for Ectropion

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Drugs for Ectropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
FluorouracilPhase 0172851-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen

Interventional clinical trials:

idNameStatusNCT IDPhase
1Hyaluronic Acid Gels for Lower Lid RetractionWithdrawnNCT01838252Phase 4
2PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic SurgeryWithdrawnNCT02761083Phase 4
3Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine CutaneousNot yet recruitingNCT01222000Phase 3
4Comparison Between Two Surgical Methods for Eyelid Ectropion: Tarsal Strip Alone Versus Tarsal Strip With Punctoplasty (Three Snips With or Without Diamond-shaped Resection)CompletedNCT02893813
5Lacrimal Drainage Resistance StudyCompletedNCT01766232
6Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface SurgeriesNot yet recruitingNCT02638610
75-fluorouracil Versus Placebo in Periocular Full Thickness Skin GraftsNot yet recruitingNCT02705352Phase 0

Search NIH Clinical Center for Ectropion


Cochrane evidence based reviews: ectropion

Genetic Tests for Ectropion

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Genetic tests related to Ectropion:

id Genetic test Affiliating Genes
1 Ectropion25

Anatomical Context for Ectropion

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MalaCards organs/tissues related to Ectropion:

34
Skin, Eye, Cervix, Testes, Lung, Bone

Animal Models for Ectropion or affiliated genes

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MGI Mouse Phenotypes related to Ectropion:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.1ABCA12, NF1, PSAT1, TWIST2
2MP:00053767.2ABCA12, NF1, PHGDH, PSAT1, SAT1, TGM1
3MP:00053786.9ABCA12, NF1, PHGDH, PSAT1, SAT1, TGM1

Publications for Ectropion

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Articles related to Ectropion:

(show top 50)    (show all 426)
idTitleAuthorsYear
1
Misdiagnosed Periocular Pyoderma Gangrenosum Requiring Ectropion Repair With Development of Second Lesion of Pyoderma Gangrenosum at Graft Site. (26934168)
2016
2
Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures. (25025386)
2014
3
Inverting Sutures With Systemic Retinoids and Lubrication Can Correct Ectropion in Ichthyosis. (25216196)
2014
4
Free transplantation of autogenous palmaris longus tendon in the repair of cicatricial ectropion of lower eyelid. (24693868)
2014
5
Re: "inverting sutures for tarsal ectropion (the leicester modified suture technique)". (24614559)
2014
6
Eyelid ectropion caused by glasses. Mechanical centurion syndrome. (23433196)
2013
7
Topical tazarotene for the treatment of ectropion in ichthyosis. (23677086)
2013
8
Tarsal ectropion repair and lower blepharoplasty: A case report and review of literature. (21764653)
2012
9
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. (21346670)
2011
10
Combined transconjunctival release and midface-lift for postblepharoplasty ectropion repair. (20479440)
2010
11
Maternal skin allograft for cicatricial ectropion in congenital icthyosis. (20090485)
2010
12
The use of fibrin tissue glue in the repair of cicatricial ectropion of the lower eyelid. (20622696)
2010
13
Kindler syndrome causing severe cicatricial ectropion. (20592640)
2010
14
The histopathology of involutional ectropion and entropion. (20029486)
2009
15
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. (18317150)
2008
16
Acute erythema and edematous skin reaction and ectropion following docetaxel in a patient with non-small cell lung cancer. (18828046)
2008
17
Management of difficult pediatric facial burns: reconstruction of burn-related lower eyelid ectropion and perioral contractures. (18650718)
2008
18
Resolution of pityriasis rubra pilaris-induced cicatricial ectropion with systemic low-dose methotrexate. (17386290)
2007
19
Correction of ectropion in facial paralysis. (16462363)
2006
20
A rare case of chondroid syringoma arising from the lower eyelid with ectropion. (17051093)
2006
21
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip. (16637845)
2006
22
Congenital ectropion uveae and glaucoma. (16476899)
2006
23
Bilateral juvenile glaucoma with iridotrabecular dysgenesis, congenital ectropion uveae, and thickened corneal nerves. (15618973)
2005
24
The E-Z(easy) clamp--a new instrument to facilitate medial ectropion repair. (16191798)
2005
25
Surgical management of cicatricial ectropion following scarring dermatopathies in two dogs. (16178849)
2005
26
Surgical Pearl: Temporary suspension suture (Frost suture) to help prevent ectropion after infraorbital reconstruction. (14639392)
2003
27
RE: "Canthus-sparing ectropion repair". (12142767)
2002
28
Prevalence and associations with ectropion in an older population: the Blue Mountains Eye Study. (11446446)
2001
29
Cicatricial ectropion in progressive skin diseases. (12045921)
2001
30
Anthrax as the cause of preseptal cellulitis and cicatricial ectropion. (11284766)
2001
31
The lateral transorbital canthopexy for correction and prevention of ectropion: report of a procedure, grading system, and outcome study. (10925417)
2000
32
Iopidine allergy causing lower eyelid ectropion progressing to cicatricial entropion. (10636681)
1999
33
Cornea and iris changes in congenital ectropion uvea after trabeculotomy. (9150525)
1997
34
Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis. (8829501)
1996
35
Temporary ectropion due to topical fluorouracil. (8187543)
1994
36
Age-related medial ectropion of the lower eyelid. (7818876)
1994
37
Correction of ectropion of the lower lid by upper eyelid skin transposition. (2052910)
1991
38
Lamellar ichthyosis and congenital ectropion. (2256850)
1990
39
The prevention and treatment of lower lid ectropion following blepharoplasty. (2349302)
1990
40
Lower eyelid ectropion following chemical face peeling. (6472784)
1984
41
Cicatricial ectropion and lacrimal obstruction associated with the sclerodermoid variant of porphyria cutanea tarda. (7211997)
1981
42
Repair of entropion and ectropion. (361598)
1978
43
The use of the "lateral canthal sling" in ectropion repair. (890590)
1977
44
Cicatricial ectropion of the lower lid. (4596775)
1973
45
Repair of ectropion using the Bick procedure. (4917172)
1970
46
A modified Kuhnt-Szymanowski procedure for ectropion and lateral canthoplasty. (5920436)
1966
47
Plastic repair of cicatricial ectropion by free transplantation. (14430302)
1959
48
Congenital ectropion and distichiasis; etiologic and hereditary factors: a report of cases and review of the literature. (13556836)
1957-1958
49
Cicatricial ectropion; its plastic repair. (14950424)
1952
50
The Operative Treatment of Trichiasis with or without Entropion, and a Short Note on Argyll Robertson's Operation for Ectropion. (20751919)
1887

Variations for Ectropion

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Expression for genes affiliated with Ectropion

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Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Pathways related to Ectropion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3PHGDH, PSAT1
2
Show member pathways
9.3PHGDH, PSAT1

GO Terms for genes affiliated with Ectropion

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Biological processes related to Ectropion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:00314249.9ABCA12, TGM1
2keratinocyte differentiationGO:00302169.8ABCA12, TGM1
3L-serine biosynthetic processGO:00065649.8PHGDH, PSAT1
4spinal cord developmentGO:00215109.4NF1, PHGDH
5neural tube developmentGO:00219159.3NF1, PHGDH

Sources for Ectropion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet