MCID: ECT005
MIFTS: 44

Ectropion malady

Eye diseases category

Summaries for Ectropion

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66Wikipedia, 34MalaCards
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Wikipedia:66 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards: Ectropion, also known as ectropion, unspecified, is related to psoriasis and skin disease. An important gene associated with Ectropion is TGM1 (transglutaminase 1). The compounds vitamin a and lipid have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and cervix, and related mouse phenotypes are craniofacial and growth/size/body.

Aliases & Classifications for Ectropion

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9Disease Ontology, 11DISEASES, 46Novoseek, 59SNOMED-CT, 28ICD9CM, 36MeSH, 63UMLS, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

ectropion 9 11 46
ectropion, unspecified 9
unspecified ectropion 9
ectropion of eyelid 9
everted margin 9
ectropion nos 9


External Ids:

Disease Ontology9 DOID:1570
ICD9CM28 374.1, 374.10
MeSH36 D004483
ICD1026 H02.1

Related Diseases for Ectropion

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18GeneCards, 19GeneDecks
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Diseases related to Ectropion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1psoriasis29.8NF1, TGM1
2skin disease29.7TGM1, ABCA12
3cicatricial ectropion10.8
4entropion10.6
5glaucoma10.5
6congenital ectropion uveae10.4
7cervicitis10.4
8senile ectropion10.4
9barber say syndrome10.3
10facial paralysis10.2
11lagophthalmos10.2
12mechanical ectropion10.2
13burns10.2
14spastic ectropion10.2
15senile entropion10.2
16vaginitis10.2
17ichthyosis alopecia eclabion ectropion mental retardation10.2
18macrostomia10.2
19blepharo-cheilo-odontic syndrome10.2
20ichthyosis - alopecia - eclabion - ectropion - intellectual disability10.2
21neurofibromatosis10.1
22juvenile glaucoma10.1
23herpes zoster10.1
24basal cell carcinoma10.1
25hypertrichosis10.1
26ectropion inferior cleft lip and or palate10.1
27ichthyosis vulgaris10.1TGM1
28paralytic lagophthalmos10.0
29pyoderma gangrenosum10.0
30sezary's disease10.0
31keratoconjunctivitis sicca10.0
32clear cell adenocarcinoma10.0
33adenocarcinoma10.0
34corneal ulcer10.0
35keratoconjunctivitis10.0
36myasthenia gravis10.0
37papilloma10.0
38pyoderma10.0
39vaginal discharge10.0
40herpes zoster ophthalmicus10.0
41kindler syndrome10.0
42say syndrome10.0
43ichthyosis, autosomal recessive 4b10.0
44ichthyosis, congenital, autosomal recessive 110.0
45ichthyosis, congenital, autosomal recessive 210.0
46euryblepharon10.0
47isolated congenital ectropion10.0
48harlequin type ichthyosis10.0TGM1, ABCA12
49autosomal recessive congenital ichthyosis10.0ABCA12, TGM1
50congenital ichthyosiform erythroderma10.0TGM1, ABCA12

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Symptoms for Ectropion

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Drugs & Therapeutics for Ectropion

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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34MalaCards
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MalaCards organs/tissues related to Ectropion:

34
Skin, Eye, Cervix, Bone, Lung, Testes

Animal Models for Ectropion or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Ectropion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.3ABCA12, UROS, NF1
2MP:00053788.2NF1, UROS, TGM1, ABCA12
3MP:00107718.1NF1, UROS, TGM1, ABCA12

Publications for Ectropion

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53PubMed
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Articles related to Ectropion:

(show top 50)    (show all 375)
idTitleAuthorsYear
1
Eyelid ectropion caused by glasses. Mechanical centurion syndrome. (23433196)
2013
2
Topical tazarotene for the treatment of ectropion in ichthyosis. (23677086)
2013
3
A novel TGM1 splicing mutation in a collodion baby with cicatricial ectropion. (24314425)
2013
4
Cicatricial ectropion: a complication of topical 5-fluorouracil. (21872544)
2012
5
Tarsal ectropion repair and lower blepharoplasty: A case report and review of literature. (21764653)
2012
6
Involutional ectropion and entropion: clinicopathologic correlation between horizontal eyelid laxity and eyelid extracellular matrix. (21490515)
2011
7
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. (21346670)
2011
8
Congenital bilateral ectropion in lamellar ichthyosis. (21713241)
2011
9
Combined transconjunctival release and midface-lift for postblepharoplasty ectropion repair. (20479440)
2010
10
Maternal skin allograft for cicatricial ectropion in congenital icthyosis. (20090485)
2010
11
The use of fibrin tissue glue in the repair of cicatricial ectropion of the lower eyelid. (20622696)
2010
12
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. (18317150)
2008
13
Acute erythema and edematous skin reaction and ectropion following docetaxel in a patient with non-small cell lung cancer. (18828046)
2008
14
Correction of ectropion in facial paralysis. (16462363)
2006
15
A rare case of chondroid syringoma arising from the lower eyelid with ectropion. (17051093)
2006
16
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip. (16637845)
2006
17
Management of lower lid ectropion. (16918568)
2006
18
Congenital ectropion uveae and glaucoma. (16476899)
2006
19
Bilateral juvenile glaucoma with iridotrabecular dysgenesis, congenital ectropion uveae, and thickened corneal nerves. (15618973)
2005
20
The E-Z(easy) clamp--a new instrument to facilitate medial ectropion repair. (16191798)
2005
21
Surgical Pearl: Temporary suspension suture (Frost suture) to help prevent ectropion after infraorbital reconstruction. (14639392)
2003
22
RE: "Canthus-sparing ectropion repair". (12142767)
2002
23
Prevalence and associations with ectropion in an older population: the Blue Mountains Eye Study. (11446446)
2001
24
Cicatricial ectropion in progressive skin diseases. (12045921)
2001
25
Anthrax as the cause of preseptal cellulitis and cicatricial ectropion. (11284766)
2001
26
The lateral transorbital canthopexy for correction and prevention of ectropion: report of a procedure, grading system, and outcome study. (10925417)
2000
27
Cornea and iris changes in congenital ectropion uvea after trabeculotomy. (9150525)
1997
28
Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis. (8829501)
1996
29
A variant of the cerebro-oculo-facio-skeletal syndrome with congenital ectropion and a case of lamellar ichthyosis in the same family. (8026108)
1994
30
Temporary ectropion due to topical fluorouracil. (8187543)
1994
31
Age-related medial ectropion of the lower eyelid. (7818876)
1994
32
Postblepharoplasty ectropion. Prevention and management. (1892615)
1991
33
Surgical correction of entropion and ectropion in the same lid. (3336659)
1988
34
Efficacy of surgical treatment for paralytic ectropion. (3627716)
1987
35
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency. (3086578)
1986
36
The histopathology of involutional ectropion. (4038795)
1985
37
Lower eyelid ectropion following chemical face peeling. (6472784)
1984
38
Cicatricial ectropion following blepharoplasty: treatment by tissue expansion. (6525580)
1984
39
Complications of blepharoplasty. Orbital hematoma, ectropion, and scleral show. (7338009)
1981
40
The ins and outs of entropion and ectropion: part II. Congenital ectropion. (974867)
1976
41
Cicatricial ectropion. (974864)
1976
42
Modifications of lower lid ectropion procedures. (1225102)
1975
43
Cicatricial ectropion of the lower lid. (4596775)
1973
44
Ectropion and entropion. (4927650)
1970
45
Repair of ectropion using the Bick procedure. (4917172)
1970
46
A modified Kuhnt-Szymanowski procedure for ectropion and lateral canthoplasty. (5920436)
1966
47
Cicatricial ectropion. (14041231)
1962
48
Plastic repair of cicatricial ectropion by free transplantation. (14430302)
1959
49
Congenital ectropion and distichiasis; etiologic and hereditary factors: a report of cases and review of the literature. (13556836)
1957-1958
50
The Operative Treatment of Trichiasis with or without Entropion, and a Short Note on Argyll Robertson's Operation for Ectropion. (20751919)
1887

Variations for Ectropion

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Expression for genes affiliated with Ectropion

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ectropion

Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Compounds for genes affiliated with Ectropion

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46Novoseek, 25HMDB, 12DrugBank
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Compounds related to Ectropion according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1vitamin a46 25 1211.0NF1, TGM1
2lipid468.7NF1, TGM1, ABCA12

GO Terms for genes affiliated with Ectropion

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17Gene Ontology
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Biological processes related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:0314249.5TGM1, ABCA12

Products for genes affiliated with Ectropion

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ectropion

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet