Aliases & Classifications for Ectropion

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 36MeSH, 29ICD9CM, 65UMLS, 59SNOMED-CT, 27ICD10
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Aliases & Descriptions for Ectropion:

Name: Ectropion 10 47 12 36
Ectropion of Eyelid 10
 
Everted Margin 10


Classifications:



External Ids:

Disease Ontology10 DOID:1570
MeSH36 D004483
ICD9CM29 374.10, 374.1
ICD1027 H02.1

Summaries for Ectropion

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Wikipedia:68 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards based summary: Ectropion, also known as ectropion of eyelid, is related to ichthyosis, autosomal recessive 4b and ichthyosis alopecia eclabion ectropion mental retardation. An important gene associated with Ectropion is TGM1 (Transglutaminase 1), and among its related pathways are Glycine, serine and threonine metabolism and Amino acid synthesis and interconversion (transamination). Affiliated tissues include skin, eye and cervix, and related mouse phenotypes are craniofacial and mortality/aging.

Related Diseases for Ectropion

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Diseases related to Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 172)
idRelated DiseaseScoreTop Affiliating Genes
1ichthyosis, autosomal recessive 4b30.4ABCA12, TGM1
2ichthyosis alopecia eclabion ectropion mental retardation30.4ABCA12, TGM1
3neu-laxova syndrome130.3PHGDH, PSAT1
4cicatricial ectropion10.8
5entropion10.7
6ichthyosis10.6
7congenital ectropion uveae10.5
8senile ectropion10.5
9cervicitis10.5
10barber-say syndrome10.4
11burns10.3
12mechanical ectropion10.3
13facial paralysis10.3
14lagophthalmos10.3
15spastic ectropion10.2
16ptosis10.2
17senile entropion10.2
18ectropion inferior cleft lip and or palate10.2
19ichthyosis - alopecia - eclabion - ectropion - intellectual disability10.2
20rheumatic congestive heart failure10.1PHGDH, PSAT1
21juvenile glaucoma10.1
22herpes zoster10.1
23neurofibromatosis10.1
24basal cell carcinoma10.1
25hypertrichosis10.1
26vaginitis10.1
27blepharo-cheilo-odontic syndrome10.1
28isolated congenital ectropion10.1
29severe pre-eclampsia10.1PHGDH, PSAT1
30charcot-marie-tooth disease, x-linked dominant, 610.1MBTPS2, SAT1
31keratosis palmoplantaris adenocarcinoma of the colon10.1MBTPS2, SAT1
32corneal deposit10.1MBTPS2, SAT1
33ichthyosis, congenital, autosomal recessive 4a10.0
34ichthyosis, congenital, autosomal recessive 610.0
35ichthyosis, congenital, autosomal recessive 110.0
36ichthyosis, congenital, autosomal recessive 210.0
37ichthyosis, congenital, autosomal recessive 310.0
38neurofibromatosis, type 110.0
39pityriasis rubra pilaris10.0
40kindler syndrome10.0
41keratosis follicularis spinulosa decalvans, x-linked10.0
42miller syndrome10.0
43myasthenia gravis10.0
44congenital ichthyosiform erythroderma10.0
45keratoconjunctivitis sicca10.0
46paralytic lagophthalmos10.0
47sezary's disease10.0
48pyoderma gangrenosum10.0
49crest syndrome10.0
50corneal ulcer10.0

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Symptoms for Ectropion

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Drugs & Therapeutics for Ectropion

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Drugs for Ectropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1EmollientsPhase 3113

Interventional clinical trials:

idNameStatusNCT IDPhase
1Hyaluronic Acid Gels for Lower Lid RetractionWithdrawnNCT01838252Phase 4
2Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine CutaneousNot yet recruitingNCT01222000Phase 3
3Lacrimal Drainage Resistance StudyCompletedNCT01766232
4Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface SurgeriesNot yet recruitingNCT02638610

Search NIH Clinical Center for Ectropion


Cochrane evidence based reviews: Ectropion

Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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MalaCards organs/tissues related to Ectropion:

33
Skin, Eye, Cervix, Testes, Lung, Bone

Animal Models for Ectropion or affiliated genes

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MGI Mouse Phenotypes related to Ectropion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0ABCA12, NF1, PHGDH, PSAT1
2MP:00107687.8ABCA12, FERMT1, NF1, PHGDH, PSAT1, TGM1
3MP:00053767.5ABCA12, FERMT1, NF1, PHGDH, SAT1, TGM1
4MP:00053786.9ABCA12, FERMT1, NF1, PHGDH, PSAT1, SAT1

Publications for Ectropion

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Articles related to Ectropion:

(show top 50)    (show all 414)
idTitleAuthorsYear
1
Surgical Management of Cicatricial Ectropion in Pityriasis Rubra Pilaris. (25794020)
2015
2
Re: "Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures". (25945875)
2015
3
Lower lid ectropion in hypohidrotic ectodermal dysplasia. (25802783)
2015
4
Caruncular Fixation in Medial Canthal Tendon Repair: The Minimally Invasive Purse String Suture for Tendinous Laxity and Medial Ectropion. (24911533)
2014
5
Age-matched, case-controlled comparison of clinical indicators for development of entropion and ectropion. (24734167)
2014
6
Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures. (25025386)
2014
7
Inverting Sutures With Systemic Retinoids and Lubrication Can Correct Ectropion in Ichthyosis. (25216196)
2014
8
Eyelid ectropion caused by glasses. Mechanical centurion syndrome. (23433196)
2013
9
Topical tazarotene for the treatment of ectropion in ichthyosis. (23677086)
2013
10
Cicatricial ectropion: a complication of topical 5-fluorouracil. (21872544)
2012
11
Tarsal ectropion repair and lower blepharoplasty: A case report and review of literature. (21764653)
2012
12
Involutional ectropion and entropion: clinicopathologic correlation between horizontal eyelid laxity and eyelid extracellular matrix. (21490515)
2011
13
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. (21346670)
2011
14
Congenital bilateral ectropion in lamellar ichthyosis. (21713241)
2011
15
Combined transconjunctival release and midface-lift for postblepharoplasty ectropion repair. (20479440)
2010
16
Maternal skin allograft for cicatricial ectropion in congenital icthyosis. (20090485)
2010
17
The use of fibrin tissue glue in the repair of cicatricial ectropion of the lower eyelid. (20622696)
2010
18
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. (18317150)
2008
19
Correction of ectropion in facial paralysis. (16462363)
2006
20
A rare case of chondroid syringoma arising from the lower eyelid with ectropion. (17051093)
2006
21
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip. (16637845)
2006
22
Management of lower lid ectropion. (16918568)
2006
23
Congenital ectropion uveae and glaucoma. (16476899)
2006
24
Bilateral juvenile glaucoma with iridotrabecular dysgenesis, congenital ectropion uveae, and thickened corneal nerves. (15618973)
2005
25
Surgical Pearl: Temporary suspension suture (Frost suture) to help prevent ectropion after infraorbital reconstruction. (14639392)
2003
26
RE: "Canthus-sparing ectropion repair". (12142767)
2002
27
Prevalence and associations with ectropion in an older population: the Blue Mountains Eye Study. (11446446)
2001
28
Cicatricial ectropion in progressive skin diseases. (12045921)
2001
29
The lateral transorbital canthopexy for correction and prevention of ectropion: report of a procedure, grading system, and outcome study. (10925417)
2000
30
Cornea and iris changes in congenital ectropion uvea after trabeculotomy. (9150525)
1997
31
Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis. (8829501)
1996
32
A variant of the cerebro-oculo-facio-skeletal syndrome with congenital ectropion and a case of lamellar ichthyosis in the same family. (8026108)
1994
33
Temporary ectropion due to topical fluorouracil. (8187543)
1994
34
Age-related medial ectropion of the lower eyelid. (7818876)
1994
35
Surgical correction of entropion and ectropion in the same lid. (3336659)
1988
36
Efficacy of surgical treatment for paralytic ectropion. (3627716)
1987
37
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency. (3086578)
1986
38
Lower eyelid ectropion following chemical face peeling. (6472784)
1984
39
Cicatricial ectropion following blepharoplasty: treatment by tissue expansion. (6525580)
1984
40
Complications of blepharoplasty. Orbital hematoma, ectropion, and scleral show. (7338009)
1981
41
The ins and outs of entropion and ectropion: part II. Congenital ectropion. (974867)
1976
42
Cicatricial ectropion. (974864)
1976
43
Paralytic ectropion. (974869)
1976
44
Modifications of lower lid ectropion procedures. (1225102)
1975
45
Ectropion and entropion. (4927650)
1970
46
Repair of ectropion using the Bick procedure. (4917172)
1970
47
A modified Kuhnt-Szymanowski procedure for ectropion and lateral canthoplasty. (5920436)
1966
48
Cicatricial ectropion. (14041231)
1962
49
Plastic repair of cicatricial ectropion by free transplantation. (14430302)
1959
50
The Operative Treatment of Trichiasis with or without Entropion, and a Short Note on Argyll Robertson's Operation for Ectropion. (20751919)
1887

Variations for Ectropion

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Expression for genes affiliated with Ectropion

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Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Pathways related to Ectropion according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5PHGDH, PSAT1
2
Show member pathways
9.5PHGDH, PSAT1

GO Terms for genes affiliated with Ectropion

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Cellular components related to Ectropion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058297.4ABCA12, FERMT1, NF1, PHGDH, PSAT1, SAT1

Biological processes related to Ectropion according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:003142410.2ABCA12, TGM1
2neural tube developmentGO:002191510.2NF1, PHGDH
3spinal cord developmentGO:002151010.1NF1, PHGDH
4cellular amino acid biosynthetic processGO:000865210.1PHGDH, PSAT1
5L-serine biosynthetic processGO:000656410.1PHGDH, PSAT1
6keratinocyte differentiationGO:003021610.0ABCA12, TGM1
7cellular nitrogen compound metabolic processGO:00346418.7PHGDH, PSAT1, SAT1
8metabolic processGO:00081528.3ABCA12, PHGDH, PSAT1, SAT1

Sources for Ectropion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet