MCID: ECT005
MIFTS: 39

Ectropion malady

Eye category

Summaries for Ectropion

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards: Ectropion, also known as ectropion, unspecified, is related to alopecia and congenital ichthyosiform erythroderma. An important gene associated with Ectropion is TGM1 (transglutaminase 1). The compound heme have been mentioned in the context of this disorder. Related mouse phenotypes are liver/biliary system and integument.

Aliases & Classifications for Ectropion

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 27ICD9CM, 57SNOMED-CT, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye


Aliases & Descriptions:

ectropion 8 10 45
ectropion, unspecified 8
unspecified ectropion 8
ectropion of eyelid 8
everted margin 8
ectropion nos 8


External Ids:

Disease Ontology8 DOID:1570
ICD9CM27 374.1, 374.10
MeSH35 D004483
ICD1025 H02.1

Related Diseases for Ectropion

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Ectropion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 124)
idRelated DiseaseScoreTop Affiliating Genes
1alopecia29.7MBTPS2
2congenital ichthyosiform erythroderma29.7CYP4F22, ABHD5, ABCA12, TGM1
3cicatricial ectropion10.8
4senile ectropion10.5
5glaucoma, congenital10.4
6congenital ectropion uveae10.4
7mechanical ectropion10.3
8senile entropion10.2
9barber say syndrome10.2
10ichthyosis alopecia eclabion ectropion mental retardation10.2
11spastic ectropion10.1
12macrostomia10.1
13blepharo-cheilo-odontic syndrome10.1
14ichthyosis - alopecia - eclabion - ectropion - intellectual deficit10.1
15neurofibromatosis10.1
16juvenile glaucoma10.1
17paralytic lagophthalmos10.1
18herpes zoster10.1
19basal cell carcinoma10.1
20ectropion inferior cleft lip and or palate10.1
21keratoconjunctivitis sicca10.0
22clear cell adenocarcinoma10.0
23cervical clear cell adenocarcinoma10.0
24pyoderma gangrenosum10.0
25sezary's disease10.0
26n syndrome10.0
27adenocarcinoma10.0
28vaginal discharge10.0
29kindler syndrome10.0
30herpes zoster ophthalmicus10.0
31ichthyosis, autosomal recessive 4b10.0
32ichthyosis, congenital, autosomal recessive 110.0
33ichthyosis, congenital, autosomal recessive 210.0
34isolated congenital ectropion10.0
35ichthyosis vulgaris10.0TGM1
36keratosis follicularis spinulosa decalvans10.0SAT1
37keratosis follicularis10.0MBTPS2, SAT1
38harlequin type ichthyosis10.0TGM1, ABCA12
39lagophthalmos10.0LAX1, MBD5
40neutral lipid storage disease10.0AADAC, ABHD5
41autosomal recessive congenital ichthyosis10.0TGM1, ABCA12, CYP4F22
42burns9.8
43cicatricial entropion9.8
44cicatricial lagophthalmos9.8
45eye carcinoma9.8
46porphyria cutanea tarda9.8
47cutis laxa9.8
48trachoma9.8
49buphthalmos9.8
50cellulitis9.8

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Clinical Features for Ectropion

Drugs & Therapeutics for Ectropion

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Ectropion

Genetic Tests for Ectropion

Anatomical Context for Ectropion

Animal Models for Ectropion or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Ectropion

Sources:
51PubMed
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Articles related to Ectropion:

(show top 50)    (show all 380)
idTitleAuthorsYear
1
Eyelid ectropion caused by glasses. Mechanical centurion syndrome. (23433196)
2013
2
Topical tazarotene for the treatment of ectropion in ichthyosis. (23677086)
2013
3
Ectropion and entropion in sub-Saharan Africa: how do we differ? (24309406)
2013
4
Marked bilateral lower eyelid ectropion in cutis laxa: a paraneoplastic process in multiple myeloma. (22551370)
2012
5
Photo quiz. Verrucous lesions and ectropion in an immunocompetent individual. (23091045)
2012
6
A split forehead flap for the treatment of resistant bilateral upper and lower eyelid ectropion postburn injury. (22461952)
2012
7
Combined transconjunctival release and midface-lift for postblepharoplasty ectropion repair. (20479440)
2010
8
Entropion-ectropion: the influence of axial globe projection on lower eyelid malposition. (19273913)
2009
9
Comment on 'minimising the risk of ectropion when full thickness skin grafting lower eyelids' Lau et al J Plast Reconstr Aesthet Surg 2008;61:1562-4. (19231310)
2009
10
Management of difficult pediatric facial burns: reconstruction of burn-related lower eyelid ectropion and perioral contractures. (18650718)
2008
11
Some historical remarks on the conservative treatment of facial paralysis--comment on 'Temporary ectropion therapy by adhesive taping: a case study'. (19019248)
2008
12
Correction of entropion and ectropion. (18453763)
2008
13
Three different consecutive manifestations of morphoeic BCC in the same patient: presenting first as ectropion, then entropion, and finally medial canthal dystopia with epicanthus inversus. (18569825)
2008
14
Use of a suture anchor for correction of ectropion in facial paralysis. (16462360)
2006
15
Corneal topography in involutional ectropion of the lower eyelid: preoperative and postoperative evaluation. (15829800)
2005
16
RE: "Canthus-sparing ectropion repair". (12142767)
2002
17
Anthrax as the cause of preseptal cellulitis and cicatricial ectropion. (11284766)
2001
18
Ectropion secondary to bolus injection of 5-fluorouracil. (11243427)
2001
19
Canthus-sparing ectropion repair. (11388380)
2001
20
Role of the lower lid retractors in involutional ectropion repair. (12045919)
2001
21
Composition of cervical smears in patients with and without a cervical ectropion. (7629284)
1995
22
Histochemical staining of orbicularis oculi muscle in ectropion and entropion. (7958041)
1994
23
Treatment of the paradoxic inversion of the lashes in ectropion. (1390425)
1992
24
Ectropion following entropion surgery: an unhappy patient and physician. (1554652)
1992
25
Correction of ectropion of the lower lid by upper eyelid skin transposition. (2052910)
1991
26
Medical ectropion repair. A new procedure. (2487218)
1989
27
Lamellar ichthyosis (collodian baby) with severe bilateral ectropion. (3255705)
1988
28
History of surgery for involutional ectropion. (3331928)
1986
29
Congenital ectropion uveae and glaucoma. (4015878)
1985
30
Cicatricial ectropion due to essential skin shrinkage: treatment with rotational upper-lid pedicle flaps. (6652570)
1983
31
Radical correction of senile entropion and ectropion. (6338536)
1983
32
Lateral tarsal strip procedure for the correction of paralytic ectropion. (7070179)
1982
33
Ectropion. (7123618)
1982
34
The use of preputial skin to replace conjunctiva and to correct ectropion. (7044459)
1982
35
Ectropion after blepharoplasty prevention and treatment. (24173840)
1978
36
Entropion and ectropion of the eyelids. (729343)
1978
37
Cicatricial ectropion secondary to 5-fluorouracil therapy. (840160)
1977
38
The ins and outs of entropion and ectropion. Clinical assessment and choice of surgical procedure. (974859)
1976
39
Modifications of lower lid ectropion procedures. (1225102)
1975
40
Ectropion and entropion. (4927650)
1970
41
Exfoliative cytology of ectopy, ectropion and epidemization. (13686040)
1961
42
Plastic repair of cicatricial ectropion by free transplantation. (14430302)
1959
43
V-Z procedure for the correction of senile ectropion. (13840478)
1959
44
Ectropion left upper eyelid corrected by skin graft; hair graft to left brow and correction of left monocular convergent strabismus. (18145663)
1949
45
Congenital ectropion of pigment border of iris. (18935337)
1948
46
Plastic Operation for Severe Cicatricial Ectropion. (19989273)
1933
47
THE PATHOLOGY OF CERVICAL ECTROPION (CERVICAL EROSION). (20317682)
1930
48
Longitudinal Section of the Cervix of an Infant showing Ectropion of the Cervical Mucosa. (19973210)
1908
49
A NOTE on a METHOD of OPERATING for ECTROPION of the LOWER EYELID. (20757881)
1898
50
The Operative Treatment of Trichiasis with or without Entropion, and a Short Note on Argyll Robertson's Operation for Ectropion. (20751919)
1887

Genetic Variations for Ectropion

Expression for genes affiliated with Ectropion

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ectropion

Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

Compounds for genes affiliated with Ectropion

Sources:
29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Ectropion according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1heme29 11 2411.5CYP4V2, CYP4F22, UROS

GO Terms for genes affiliated with Ectropion

Sources:
16Gene Ontology
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Biological processes related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratinizationGO:0314249.7TGM1, ABCA12
2positive regulation of triglyceride catabolic processGO:0108989.6AADAC, ABHD5

Molecular functions related to Ectropion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1monooxygenase activityGO:0044979.8CYP4V2, CYP4F22
2oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenGO:0167059.7CYP4V2, CYP4F22
3triglyceride lipase activityGO:0048069.6AADAC, ABHD5

Products for genes affiliated with Ectropion

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ectropion

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet