Aliases & Classifications for Ectropion

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Aliases & Descriptions for Ectropion:

Name: Ectropion 10 47 12 36
Ectropion of Eyelid 10
 
Everted Margin 10

Classifications:



External Ids:

Disease Ontology10 DOID:1570
ICD9CM29 374.1, 374.10
MeSH36 D004483
UMLS65 C0013592

Summaries for Ectropion

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Wikipedia:68 Ectropion is a medical condition in which the lower eyelid turns outwards. It is one of the notable... more...

MalaCards based summary: Ectropion, also known as ectropion of eyelid, is related to neu-laxova syndrome1 and ichthyosis, autosomal recessive 4b. An important gene associated with Ectropion is TGM1 (Transglutaminase 1), and among its related pathways are Glycine, serine and threonine metabolism and Amino acid synthesis and interconversion (transamination). Affiliated tissues include skin, heart and breast, and related mouse phenotypes are liver/biliary system and craniofacial.

Related Diseases for Ectropion

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Diseases related to Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 140)
idRelated DiseaseScoreTop Affiliating Genes
1neu-laxova syndrome130.6PHGDH, PSAT1
2ichthyosis, autosomal recessive 4b30.2ABCA12, TGM1
3spastic ectropion28.5ABCA12, DNAAF3, MBTPS2, NF1, PHGDH, PSAT1
4cicatricial ectropion12.1
5congenital ectropion uveae12.1
6senile ectropion12.1
7mechanical ectropion12.1
8ectropion inferior cleft lip and or palate11.9
9ichthyosis alopecia eclabion ectropion mental retardation11.8
10ichthyosis-alopecia-eclabion-ectropion-intellectual disability syndrome11.8
11isolated congenital ectropion11.8
12barber-say syndrome11.7
13blepharo-cheilo-odontic syndrome11.0
14jones hersh yusk syndrome10.9
15mandibulofacial dysostosis-macroblepharon-macrostomia syndrome10.9
16euryblepharon10.4
17philophthalmiasis10.4PHGDH, PSAT1
18entropion10.4
19psph deficiency10.3PHGDH, PSAT1
20charcot-marie-tooth disease, x-linked dominant, 610.3MBTPS2, SAT1
21keratosis palmoplantaris adenocarcinoma of the colon10.3MBTPS2, SAT1
22bronchopneumonia10.2MBTPS2, SAT1
23hypertensive encephalopathy10.2MBTPS2, SAT1
24cervicitis10.2
25diabetic polyneuropathy10.2ABCA12, TGM1
26fallopian tube clear cell adenocarcinoma10.1ABCA12, TGM1
27otosclerosis 410.1MBTPS2, SAT1
28ichthyosis vulgaris10.1ABCA12, TGM1
29clear cell meningioma10.1MBTPS2, SAT1
30burns10.0
31lagophthalmos10.0
32facial paralysis10.0
33ptosis10.0
34ichthyosis, cyclic, with epidermolytic hyperkeratosis9.9ABCA12, TGM1
35endocrine gland cancer9.9ABCA12, TGM1
36senile entropion9.9
37vaginitis9.9
38acute necrotizing encephalitis9.9NF1, PHGDH
39juvenile glaucoma9.9
40basal cell carcinoma9.9
41hypertrichosis9.9
42pyoderma9.9
43herpes zoster9.9
44pyoderma gangrenosum9.9
45neurofibromatosis9.9
46periostitis9.9
47brca1 and brca2 hereditary breast and ovarian cancer9.8ABCA12, TGM1
48ichthyosis, congenital, autosomal recessive 4a9.8
49ichthyosis, congenital, autosomal recessive 69.8
50ichthyosis, congenital, autosomal recessive 109.8

Graphical network of the top 20 diseases related to Ectropion:



Diseases related to ectropion

Symptoms for Ectropion

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Drugs & Therapeutics for Ectropion

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Drugs for Ectropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Immunologic FactorsPhase 4, Phase 018483
2EmollientsPhase 3121
3Dermatologic AgentsPhase 34555
4
FluorouracilapprovedPhase 0168451-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
5Immunosuppressive AgentsPhase 010422
6AntimetabolitesPhase 09454
7Antimetabolites, AntineoplasticPhase 05770

Interventional clinical trials:

idNameStatusNCT IDPhase
1PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic SurgeryNot yet recruitingNCT02761083Phase 4
2Hyaluronic Acid Gels for Lower Lid RetractionWithdrawnNCT01838252Phase 4
3Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine CutaneousNot yet recruitingNCT01222000Phase 3
4Lacrimal Drainage Resistance StudyCompletedNCT01766232
5Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface SurgeriesNot yet recruitingNCT02638610
65-fluorouracil Versus Placebo in Periocular Full Thickness Skin GraftsNot yet recruitingNCT02705352Phase 0

Search NIH Clinical Center for Ectropion


Cochrane evidence based reviews: ectropion

Genetic Tests for Ectropion

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Anatomical Context for Ectropion

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MalaCards organs/tissues related to Ectropion:

33
Skin, Heart, Breast, Lung, Prostate, T cells, Endothelial

Animal Models for Ectropion or affiliated genes

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MGI Mouse Phenotypes related to Ectropion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4DNAAF3, NF1, SAT1, TWIST2
2MP:00053828.2ABCA12, NF1, PSAT1, TWIST2
3MP:00053847.3ABCA12, DNAAF3, NF1, PHGDH, SAT1, TWIST2
4MP:00053786.6ABCA12, DNAAF3, NF1, PHGDH, PSAT1, SAT1

Publications for Ectropion

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Articles related to Ectropion:

(show top 50)    (show all 426)
idTitleAuthorsYear
1
Misdiagnosed Periocular Pyoderma Gangrenosum Requiring Ectropion Repair With Development of Second Lesion of Pyoderma Gangrenosum at Graft Site. (26934168)
2016
2
Surgical Management of Cicatricial Ectropion in Pityriasis Rubra Pilaris. (25794020)
2015
3
Re: "Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures". (25945875)
2015
4
Lower lid ectropion in hypohidrotic ectodermal dysplasia. (25802783)
2015
5
Caruncular Fixation in Medial Canthal Tendon Repair: The Minimally Invasive Purse String Suture for Tendinous Laxity and Medial Ectropion. (24911533)
2014
6
Age-matched, case-controlled comparison of clinical indicators for development of entropion and ectropion. (24734167)
2014
7
Lower eyelid involutional ectropion repair with lateral tarsal strip and internal retractor reattachment with full-thickness eyelid sutures. (25025386)
2014
8
Inverting Sutures With Systemic Retinoids and Lubrication Can Correct Ectropion in Ichthyosis. (25216196)
2014
9
Eyelid ectropion caused by glasses. Mechanical centurion syndrome. (23433196)
2013
10
Topical tazarotene for the treatment of ectropion in ichthyosis. (23677086)
2013
11
Cicatricial ectropion: a complication of topical 5-fluorouracil. (21872544)
2012
12
Tarsal ectropion repair and lower blepharoplasty: A case report and review of literature. (21764653)
2012
13
Involutional ectropion and entropion: clinicopathologic correlation between horizontal eyelid laxity and eyelid extracellular matrix. (21490515)
2011
14
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. (21346670)
2011
15
Congenital bilateral ectropion in lamellar ichthyosis. (21713241)
2011
16
Combined transconjunctival release and midface-lift for postblepharoplasty ectropion repair. (20479440)
2010
17
Maternal skin allograft for cicatricial ectropion in congenital icthyosis. (20090485)
2010
18
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. (18317150)
2008
19
Correction of ectropion in facial paralysis. (16462363)
2006
20
A rare case of chondroid syringoma arising from the lower eyelid with ectropion. (17051093)
2006
21
Correction of involutional lower eyelid medial ectropion with transconjunctival approach retractor plication and lateral tarsal strip. (16637845)
2006
22
Bilateral juvenile glaucoma with iridotrabecular dysgenesis, congenital ectropion uveae, and thickened corneal nerves. (15618973)
2005
23
Surgical Pearl: Temporary suspension suture (Frost suture) to help prevent ectropion after infraorbital reconstruction. (14639392)
2003
24
RE: "Canthus-sparing ectropion repair". (12142767)
2002
25
Prevalence and associations with ectropion in an older population: the Blue Mountains Eye Study. (11446446)
2001
26
Cicatricial ectropion in progressive skin diseases. (12045921)
2001
27
The lateral transorbital canthopexy for correction and prevention of ectropion: report of a procedure, grading system, and outcome study. (10925417)
2000
28
Cornea and iris changes in congenital ectropion uvea after trabeculotomy. (9150525)
1997
29
Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis. (8829501)
1996
30
A variant of the cerebro-oculo-facio-skeletal syndrome with congenital ectropion and a case of lamellar ichthyosis in the same family. (8026108)
1994
31
Temporary ectropion due to topical fluorouracil. (8187543)
1994
32
Age-related medial ectropion of the lower eyelid. (7818876)
1994
33
Surgical correction of entropion and ectropion in the same lid. (3336659)
1988
34
Efficacy of surgical treatment for paralytic ectropion. (3627716)
1987
35
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency. (3086578)
1986
36
Lower eyelid ectropion following chemical face peeling. (6472784)
1984
37
Cicatricial ectropion following blepharoplasty: treatment by tissue expansion. (6525580)
1984
38
Complications of blepharoplasty. Orbital hematoma, ectropion, and scleral show. (7338009)
1981
39
The ins and outs of entropion and ectropion: part II. Congenital ectropion. (974867)
1976
40
Cicatricial ectropion. (974864)
1976
41
Paralytic ectropion. (974869)
1976
42
Modifications of lower lid ectropion procedures. (1225102)
1975
43
Ectropion and entropion. (4927650)
1970
44
Repair of ectropion using the Bick procedure. (4917172)
1970
45
A modified Kuhnt-Szymanowski procedure for ectropion and lateral canthoplasty. (5920436)
1966
46
Cicatricial ectropion. (14041231)
1962
47
Plastic repair of cicatricial ectropion by free transplantation. (14430302)
1959
48
The Operative Treatment of Trichiasis with or without Entropion, and a Short Note on Argyll Robertson's Operation for Ectropion. (20751919)
1887
49
50

Variations for Ectropion

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Expression for genes affiliated with Ectropion

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Search GEO for disease gene expression data for Ectropion.

Pathways for genes affiliated with Ectropion

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Pathways related to Ectropion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6PHGDH, PSAT1
2
Show member pathways
9.6PHGDH, PSAT1

GO Terms for genes affiliated with Ectropion

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Biological processes related to Ectropion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratinocyte differentiationGO:003021610.0ABCA12, TGM1
2spinal cord developmentGO:00215109.8NF1, PHGDH
3neural tube developmentGO:00219159.6NF1, PHGDH
4regulation of gene expressionGO:00104689.3NF1, PHGDH

Sources for Ectropion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet