MCID: ECZ002
MIFTS: 52

Eczema Herpeticum malady

Infectious diseases, Eye diseases, Skin diseases categories

Summaries for Eczema Herpeticum

About this section


Disease Ontology:10 A herpes simplex that results in infection located in skin, effected by preexisting dermatosis, has material basis in human herpesvirus 1 or human herpesvirus 2. the infection has symptom watery blisters, has symptom fever, and has symptom swelling of the lymph nodes.

MalaCards based summary: Eczema Herpeticum, also known as herpes simplex dermatitis of eyelid, is related to dermatitis and atopic dermatitis, and has symptoms including watery blisters, fever and swelling of the lymph nodes. An important gene associated with Eczema Herpeticum is KLK12 (kallikrein-related peptidase 12), and among its related pathways are Immune response IFN alpha beta signaling pathway and MSP-RON Signaling. The compounds polymyxin b and citrulline have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and lymph node, and related mouse phenotypes are immune system and hematopoietic system.

Wikipedia:65 Eczema herpeticum is a rare but severe disseminated infection that generally occurs at sites of skin... more...

Aliases & Classifications for Eczema Herpeticum

About this section
Sources:
10Disease Ontology, 12DISEASES, 45Novoseek, 62UMLS, 29ICD9CM, 57SNOMED-CT, 27ICD10
See all sources

Eczema Herpeticum, Aliases & Descriptions:

Name: Eczema Herpeticum 10 12 45 62
Herpes Simplex Dermatitis of Eyelid 10 62
Herpes Simplex Eyelid Dermatitis 10 62
 
Herpes Simplex Dermatitis 10 62
Herpes Simplex Virus Eyelid Dermatitis 10
Herpes Simplex Virus Dermatitis 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Eye diseases, Skin diseases


External Ids:

Disease Ontology10 DOID:9123
ICD9CM29 054.41
ICD1027 B00.0

Related Diseases for Eczema Herpeticum

About this section

Graphical network of the top 20 diseases related to Eczema Herpeticum:



Diseases related to eczema herpeticum

Symptoms for Eczema Herpeticum

About this section


Symptoms:

 10
  • watery blisters
  • fever
  • swelling of the lymph nodes

Drugs & Therapeutics for Eczema Herpeticum

About this section

Drug clinical trials:

Search ClinicalTrials for Eczema Herpeticum

Search NIH Clinical Center for Eczema Herpeticum

Genetic Tests for Eczema Herpeticum

About this section

Anatomical Context for Eczema Herpeticum

About this section

MalaCards organs/tissues related to Eczema Herpeticum:

33
Skin, Lymph node, T cells, Bone marrow, Bone, Colon, Breast

FMA organs/tissues related to Eczema Herpeticum:

16
Skin

Animal Models for Eczema Herpeticum or affiliated genes

About this section

MGI Mouse Phenotypes related to Eczema Herpeticum:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.5FLG, IRF2, TSLP, IFNG, IL7R, CAMP
2MP:00053977.2CAMP, IGHE, FLG, IRF2, TSLP, IFNG

Publications for Eczema Herpeticum

About this section

Articles related to Eczema Herpeticum:

(show top 50)    (show all 123)
idTitleAuthorsYear
1
A corneal dendritic lesion with a skin eruption: eczema herpeticum, an important differential diagnosis. (25636633)
2015
2
Eczema Herpeticum in a Wrestler. (24714395)
2014
3
Pathological role of regulatory T cells in the initiation and maintenance of eczema herpeticum lesions. (24379126)
2014
4
Atopic dermatitis complicated by eczema herpeticum is associated with HLA B7 and reduced interferon-I^-producing CD8+ T cells. (23600999)
2013
5
Eczema herpeticum with herpetic folliculitis after bone marrow transplant under prophylactic acyclovir: are patients with underlying dermatologic disorders at higher risk? (23387866)
2013
6
What is your diagnosis? The diagnosis: Kaposi varicelliform eruption (Eczema herpeticum). (22908727)
2012
7
Eczema herpeticum complicating topical 5-Fluorouracil therapy. (23010835)
2012
8
Eczema herpeticum. (22433376)
2012
9
Eczema herpeticum in children: clinical features and factors predictive of hospitalization. (22575249)
2012
10
Eczema herpeticum: a medical emergency. (23242894)
2012
11
The clinical spectrum and therapeutic challenge of eczema herpeticum. (21261703)
2011
12
Delayed acyclovir and outcomes of children hospitalized with eczema herpeticum. (22084327)
2011
13
Atopic dermo-respiratory syndrome is a correlate of eczema herpeticum. (21255038)
2011
14
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. (21510509)
2011
15
Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization. (21211653)
2011
16
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. (20466416)
2010
17
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. (19541356)
2009
18
Fatal outcome due to bacterial superinfection of eczema herpeticum in a patient with mycosis fungoides. (18713601)
2008
19
Molecular pathogenesis and clinical implications of eczema herpeticum. (18620613)
2008
20
Eczema herpeticum complicating Parthenium dermatitis. (16036117)
2005
21
High frequency of detection of herpes simplex virus DNA in the oral cavity of patients with eczema herpeticum. (15316162)
2004
22
Eczema herpeticum: a dermatologic emergency. (12430518)
2002
23
Photo quiz. Eczema herpeticum. (11398758)
2001
24
Eczema herpeticum during treatment of atopic dermatitis with 0.1% tacrolimus ointment. (11096198)
2000
25
Detection of Herpes simplex virus DNA in non-herpetic areas of patients with eczema herpeticum. (10773695)
2000
26
Microbiology of infected eczema herpeticum. (9555806)
1998
27
Eczema herpeticum in association with familial benign chronic pemphigus. (8432925)
1993
28
Eczema herpeticum induced by sun exposure. (1634302)
1992
29
Eczema herpeticum occurring in autografted skin. (2061459)
1991
30
A rapidly progressive papulovesicular eruption. Eczema herpeticum/Kaposi's varicelliform eruption. (2684026)
1989
31
Severe eczema herpeticum is associated with prolonged depression of cell-mediated immunity to herpes simplex virus. (2545414)
1989
32
Death from eczema herpeticum in a child with severe eczema, mental retardation and cataracts. (2704016)
1989
33
Eczema herpeticum. Clinical and laboratory features. (2835199)
1988
34
Increasing incidence of eczema herpeticum: analysis of seventy-five cases. (3204177)
1988
35
Treatment of eczema herpeticum with oral acyclovir. (3044093)
1988
36
Eczema herpeticum in three siblings: clinical features and acyclovir treatment. (3546436)
1986
37
Eczema herpeticum treated with oral acyclovir. (3771849)
1986
38
Acyclovir therapy for eczema herpeticum in infants. (4051523)
1985
39
Is eczema herpeticum associated with the use of hot tubs? (4011510)
1985
40
Eczema herpeticum of the child. An unusual manifestation of herpes simplex virus infection. (2996817)
1985
41
Treatment of eczema herpeticum with systemic acyclovir. (3977349)
1985
42
A case of femoral neuropathy associated with eczema herpeticum. (55494)
1976
43
Editorial: Methylene blue for eczema herpeticum. (1173927)
1975
44
Eczema herpeticum. Treatment with methylene blue and light. (170870)
1975
45
Eczema vaccinatum and eczema herpeticum in Darier disease. (4121405)
1973
46
Visceral involvement by herpes simplex virus in eczema herpeticum. (4300208)
1968
47
ECZEMA HERPETICUM AS COMPLICATION OF DARIER'S DISEASE. (14295511)
1965
48
RECURRENT ECZEMA HERPETICUM. WIDESPREAD CUTANEOUS HERPES SIMPLEX IN ATOPIC PATIENT WITHOUT ACTIVE ATOPIC DERMATITIS. (14164964)
1964
49
Kaposi's varicelliform eruption (eczema herpeticum) treated with prednisone. (13567719)
1958
50
Treatment of eczema herpeticum with gamma globulin. (13468788)
1957

Variations for Eczema Herpeticum

About this section

Expression for genes affiliated with Eczema Herpeticum

About this section

Search GEO for disease gene expression data for Eczema Herpeticum.

Pathways for genes affiliated with Eczema Herpeticum

About this section

Compounds for genes affiliated with Eczema Herpeticum

About this section

Compounds related to Eczema Herpeticum according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1polymyxin b459.9IFNG, CAMP
2citrulline45 2610.9IFNG, FLG
3rolipram45 61 3011.8IFNG, CAMP
4salbutamol45 51 30 26 1313.8IGHE, CAMP
5pgd2459.7IGHE, CAMP
6budesonide45 51 1311.6IGHE, IFNG
7calcitriol45 61 26 1312.6CAMP, IFNG, FLG
8fluticasone propionate45 51 61 1312.6IGHE, IFNG
9ionomycin459.5CAMP, IL7R, IFNG
10pentoxifylline45 1310.5CAMP, IFNG
112,5-oligoadenylate459.5OAS2, IRF2, IFNG
12l-nmma459.4IFNG, IGHE
13tarc459.4IGHE, TSLP, IFNG
14ivig459.3IGHE, IFNG
15infliximab45 51 1311.3IGHE, FLG, IFNG
16pge1459.2CAMP, IGHE
17histamine45 30 2611.2CAMP, IFNG, IGHE
18actinomycin d459.1CAMP, IFNG, IGHE
19heparin45 30 26 1312.1CAMP, IL7R, IGHE
20nitric oxide45 26 1311.1CAMP, IFNG, IRF2, FLG
21allergens459.0IFNG, TSLP, FLG, IGHE
22tyrosine458.9CAMP, IL7R, TSLP, IRF2, FLG
23retinoic acid45 269.5IGHE, FLG, IRF2, IFNG, CAMP

GO Terms for genes affiliated with Eczema Herpeticum

About this section

Biological processes related to Eczema Herpeticum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1type I interferon signaling pathwayGO:00603379.7IRF2, OAS2
2establishment of skin barrierGO:00614369.5FLG, FLG2
3interferon-gamma-mediated signaling pathwayGO:00603339.2IFNG, IRF2, OAS2
4cytokine-mediated signaling pathwayGO:00192218.9OAS2, IRF2, IFNG

Molecular functions related to Eczema Herpeticum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1antigen bindingGO:00038239.4IL7R, IGHE

Products for genes affiliated with Eczema Herpeticum

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Eczema Herpeticum

About this section
4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet