MCID: EHR002
MIFTS: 43

Ehrlichiosis malady

Categories: Rare diseases, Infectious diseases, Blood diseases

Aliases & Classifications for Ehrlichiosis

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 2CDC, 27ICD10, 29ICD9CM, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Ehrlichiosis:

Name: Ehrlichiosis 10 45 47 12 51 36 65
Human Ehrlichiosis 10 45 2 65
 
He 45

Characteristics:

Orphanet epidemiological data:

51
ehrlichiosis:
Prevalence: 1-9/1000000 (United States); Age of onset: All ages

Classifications:



External Ids:

Disease Ontology10 DOID:10242
ICD1027 A77.4, A77.40
ICD9CM29 082.4, 082.40
MeSH36 D016873
SNOMED-CT59 77361002
Orphanet51 1902
ICD10 via Orphanet28 A48.8
MESH via Orphanet37 D016873
UMLS via Orphanet66 C0085399
UMLS65 C0085399, C0343771

Summaries for Ehrlichiosis

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Disease Ontology:10 A primary bacterial infectious disease that results in infection located in leukocyte, has material basis in Ehrlichia chaffeensis or Anaplasma phagocytophilum, which are transmitted by lone start stick and transmitted by black-legged tick respectively. The infection has symptom headache, has symptom muscle aches, has symptom fatigue and has symptom rash.

MalaCards based summary: Ehrlichiosis, also known as human ehrlichiosis, is related to human monocytic ehrlichiosis and human granulocytic anaplasmosis, and has symptoms including headache, muscle aches and fatigue. An important gene associated with Ehrlichiosis is SELPLG (Selectin P Ligand), and among its related pathways are Legionellosis and Insulin receptor recycling. Affiliated tissues include leukocyte, monocytes and breast, and related mouse phenotypes are renal/urinary system and hematopoietic system.

Wikipedia:68 Ehrlichiosis is a tickborne bacterial infection, caused by bacteria of the family Anaplasmataceae,... more...

Related Diseases for Ehrlichiosis

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Graphical network of the top 20 diseases related to Ehrlichiosis:



Diseases related to ehrlichiosis

Symptoms for Ehrlichiosis

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Symptoms:

 10
  • headache
  • muscle aches
  • fatigue
  • rash

Drugs & Therapeutics for Ehrlichiosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Ehrlichiosis


Cochrane evidence based reviews: ehrlichiosis

Genetic Tests for Ehrlichiosis

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Anatomical Context for Ehrlichiosis

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MalaCards organs/tissues related to Ehrlichiosis:

33
Monocytes, Breast, Prostate, Endothelial, Testes, Liver, Heart

FMA organs/tissues related to Ehrlichiosis:

16
Leukocyte

Animal Models for Ehrlichiosis or affiliated genes

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MGI Mouse Phenotypes related to Ehrlichiosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.5ANK1, CASP3, CD40LG, CYBB, SELPLG
2MP:00053977.7ANK1, CASP3, CD40LG, CYBB, FUT7, SELPLG
3MP:00053877.4ANK1, CASP3, CD40LG, CYBB, FUT7, SELPLG

Publications for Ehrlichiosis

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Articles related to Ehrlichiosis:

(show top 50)    (show all 538)
idTitleAuthorsYear
1
Comparison of the acute phase protein and antioxidant responses in dogs vaccinated against canine monocytic ehrlichiosis and naive-challenged dogs. (25888870)
2015
2
Comparative Evaluation of the Vector Competence of Four South American Populations of the Rhipicephalus sanguineus Group for the Bacterium Ehrlichia canis, the Agent of Canine Monocytic Ehrlichiosis. (26414283)
2015
3
Sinus Bradycardia: Can We Blame Ehrlichiosis? (25232718)
2014
4
Prevalence of borreliosis, anaplasmosis, ehrlichiosis and Dirofilaria immitis in dogs and vectors in Voronezh Reserve (Russia). (24054985)
2013
5
Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis. (24144475)
2013
6
Social-ecological factors determine spatial variation in human incidence of tick-borne ehrlichiosis. (24280291)
2013
7
Serum acute phase proteins as clinical phase indicators and outcome predictors in naturally occurring canine monocytic ehrlichiosis. (21564293)
2011
8
Effect of desmopressin on immune-mediated haemorrhagic disorders due to canine monocytic ehrlichiosis: a preliminary study. (21108506)
2010
9
Clinical, serological, and molecular evidence of ehrlichiosis and anaplasmosis in dogs in Tunisia. (19018569)
2009
10
The importance of early treatment with doxycycline in human ehrlichiosis. (18344803)
2008
11
Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis. (17562770)
2007
12
Two cases of human granulocytic ehrlichiosis in Sardinia, Italy confirmed by PCR. (17114774)
2006
13
Surveys on seroprevalence of canine monocytic ehrlichiosis among dogs living in the Ivory Coast and Gabon and evaluation of a quick commercial test kit dot-ELISA. (17114755)
2006
14
Bone marrow mastocytosis in dogs with myelosuppressive monocytic ehrlichiosis (Ehrlichia canis): a retrospective study. (16967415)
2006
15
Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis. (14742542)
2004
16
Overproduction of TNF-alpha by CD8+ type 1 cells and down-regulation of IFN-gamma production by CD4+ Th1 cells contribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichiosis. (14734762)
2004
17
Hepatic pathology in human monocytic ehrlichiosis. Ehrlichia chaffeensis infection. (12817434)
2003
18
Comparison of patients fulfilling criteria for confirmed and probable human granulocytic ehrlichiosis. (12860648)
2003
19
Evaluation of cytology in the diagnosis of acute canine monocytic ehrlichiosis (Ehrlichia canis): a comparison between five methods. (12458168)
2003
20
Epidemiological, clinical and laboratory distinction between human granulocytic ehrlichiosis and the initial phase of tick-borne encephalitis. (12422617)
2002
21
Ehrlichiosis in Ixodes ricinus and wild mammals. (12141732)
2002
22
Granulocytic ehrlichiosis in Swedish dogs and horses. (12141731)
2002
23
Serologic evidence of ehrlichiosis among humans and wild animals in The Netherlands. (11915850)
2002
24
Tissue diagnosis of Ehrlichia chaffeensis in patients with fatal ehrlichiosis by use of immunohistochemistry, in situ hybridization, and polymerase chain reaction. (11716122)
2001
25
Molecular typing of the etiologic agent of human granulocytic ehrlichiosis. (11526190)
2001
26
Serologic evidence of human monocytic and granulocytic ehrlichiosis in Israel. (10827125)
2000
27
Human granulocytic ehrlichiosis agent infection in a pony vaccinated with a Borrelia burgdorferi recombinant OspA vaccine and challenged by exposure to naturally infected ticks. (10618280)
2000
28
A simian model of human granulocytic ehrlichiosis. (10403332)
1999
29
Ehrlichia chaffeensis and E. sennetsu, but not the human granulocytic ehrlichiosis agent, colocalize with transferrin receptor and up-regulate transferrin receptor mRNA by activating iron-responsive protein 1. (10225882)
1999
30
Human granulocytic ehrlichiosis in Northern California: two case descriptions with genetic analysis of the Ehrlichiae. (10476747)
1999
31
Recurrent human granulocytic ehrlichiosis and Lyme disease. (10383360)
1999
32
Cell cycle effects and induction of apoptosis caused by infection of HL-60 cells with human granulocytic ehrlichiosis pathogen measured by flow and laser scanning cytometry. (9725558)
1998
33
Immunoserologic evidence of Human Granulocytic Ehrlichiosis in Danish patients with Lyme neuroborreliosis. (9730306)
1998
34
Serologic evidence of a natural infection of white-tailed deer with the agent of human granulocytic ehrlichiosis in Wisconsin and Maryland. (9801331)
1998
35
Granulocytic ehrlichiosis: an emerging or rediscovered tick-borne disease? (9879965)
1998
36
Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course. (9650986)
1998
37
Heat shock protein 70 of the agent of human granulocytic ehrlichiosis binds to Borrelia burgdorferi antibodies. (9455892)
1998
38
Detection of the agent of human granulocytic ehrlichiosis (HGE) in UK ticks using polymerase chain reaction. (10030718)
1998
39
Serological evidence of human granulocytic ehrlichiosis in Switzerland. (9665305)
1998
40
Lyme disease and human granulocytic ehrlichiosis. (9322603)
1997
41
Characterization of an immunoreactive protein from the agent of human granulocytic ehrlichiosis. (9114402)
1997
42
Human ehrlichiosis--Maryland, 1994. (8926996)
1996
43
A human case of monocytic ehrlichiosis with adult respiratory distress syndrome in northern California. (8764635)
1996
44
Geographic, clinical, serologic, and molecular evidence of granulocytic ehrlichiosis, a likely zoonotic disease, in Minnesota and Wisconsin dogs. (8748270)
1996
45
Human ehrlichiosis in the United States. (8714253)
1996
46
Apoptosis of gamma/delta T cells in human ehrlichiosis. (8623774)
1996
47
Human ehrlichiosis. (7591456)
1995
48
Ehrlichiosis in Belgium. (7475691)
1995
49
Human ehrlichiosis in a liver transplant recipient. (7482752)
1995
50
From the Centers for Disease Control and Prevention. Human granulocytic ehrlichiosis--New York, 1995. (7674488)
1995

Variations for Ehrlichiosis

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Expression for genes affiliated with Ehrlichiosis

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Search GEO for disease gene expression data for Ehrlichiosis.

Pathways for genes affiliated with Ehrlichiosis

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GO Terms for genes affiliated with Ehrlichiosis

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Cellular components related to Ehrlichiosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basolateral plasma membraneGO:00163239.8ANK1, TFRC

Biological processes related to Ehrlichiosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intrinsic apoptotic signaling pathwayGO:00971939.6APOPT1, CASP3

Sources for Ehrlichiosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet