MCID: ELP001
MIFTS: 32

Elephantiasis malady

Summaries for Elephantiasis

Sources:
3CDC, 64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
CDC:3 Lymphatic filariasis, considered globally as a neglected tropical disease, is a parasitic disease caused by microscopic, thread-like worms. The adult worms only live in the human lymph system. The lymph system maintains the body's fluid balance and fights infections. Lymphatic filariasis is spread from person to person by mosquitoes.

MalaCards: Elephantiasis, also known as elephantiasis nos, is related to onchocerciasis and filarial elephantiasis. An important gene associated with Elephantiasis is RNASE3 (ribonuclease, RNase A family, 3). The drug ivermectin and the compounds ozone and n-formylmethionyl-leucylphenylalanine have been mentioned in the context of this disorder.

Wikipedia:64 Elephantiasis /ˌɛlɨfənˈtaɪ.əsɨs/ EL-i-fən-TY-ə-sis is a disease that is characterized by the... more...

Aliases & Classifications for Elephantiasis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 40NCIt, 35MeSH
See all sources

Aliases & Descriptions:

elephantiasis 8 10 45 61
elephantiasis nos 8


External Ids:

Disease Ontology8 DOID:4976
NCIt40 C34569
MeSH35 D004604

Related Diseases for Elephantiasis

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Elephantiasis:



Diseases related to elephantiasis

Clinical Features for Elephantiasis

Drugs & Therapeutics for Elephantiasis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Elephantiasis

Drug clinical trials:

Search ClinicalTrials for Elephantiasis

Search NIH Clinical Center for Elephantiasis

Search CenterWatch for Elephantiasis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Elephantiasis

Anatomical Context for Elephantiasis

Animal Models for Elephantiasis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Elephantiasis

Sources:
51PubMed
See all sources

Articles related to Elephantiasis:

(show top 50)    (show all 402)
idTitleAuthorsYear
1
Elephantiasis nostras verrucosa in a patient with obesity and chronic venous insufficiency. (23432135)
2013
2
Double autologous lymph node transplantation (ALNT) at the level of the knee and inguinal region for advanced lymphoedema of the lower limb (elephantiasis). (24269710)
2013
3
Elephantiasis nostras verrucosa: swelling with verrucose appearance of lower limbs. (23064932)
2012
4
Verruciform xanthoma: localized lymphedema (elephantiasis) is an essential pathogenic factor. (21362016)
2012
5
Huge vulval elephantiasis: Anesthetic management for caesarean delivery. (21897527)
2011
6
Elephantine but not elephantiasis: Subcutaneous zygomycosis. (21553211)
2011
7
Scrotal elephantiasis secondary to hidradenitis suppurativa. (21496708)
2011
8
Elephantiasis nostras verrucosa on the abdomen of a Turkish female patient caused by morbid obesity. (20804691)
2010
9
Podoconiosis - non-filarial geochemical elephantiasis - a neglected tropical disease? (20096054)
2010
10
An integrative treatment for lower limb lymphedema (elephantiasis). (20180687)
2010
11
Elephantiasis of the external genitalia: a sequel to cutaneous tuberculosis. (20049271)
2009
12
Elephantiasis nostras verrucosa. (19753577)
2009
13
Elephantiasis neuromatosa in a patient with neurofibromatosis type 1. (18181981)
2008
14
Syphilitic elephantiasis of penis and scrotum. (18270952)
2007
15
The burden of non-filarial elephantiasis in Ethiopia. (17764710)
2007
16
Elephantiasis neuromatosa in neurofibromatis type I. MRI findings with review of the literature. (16528208)
2006
17
Podoconiosis: endemic nonfilarial elephantiasis. (15735414)
2005
18
Elephantiasis nostrum verrucosa of the abdomen: clinical results with tazarotene. (15303792)
2004
19
Congenital elephantiasis-like lymphangiomatosis of a lower limb. (12636021)
2003
20
Reactivity to bacterial, fungal, and parasite antigens in patients with lymphedema and elephantiasis. (12135288)
2002
21
Stewart-Treves syndrome in a patient with elephantiasis. (10426930)
1999
22
Adverse reactions following diethylcarbamazine (DEC) intake in 'endemic normals', microfilaraemics and elephantiasis patients. (10492800)
1999
23
Elephantiasis in Pawe settlement area: podoconiosis or bancroftian filariasis? (10214438)
1997
24
Elephantiasis nostras: a case report. (8568126)
1996
25
Computed tomography of elephantiasis neuromatosa. (2910937)
1989
26
Non-filarial elephantiasis in Nyambene range: a geochemical disease. (3743481)
1986
27
Lymphedema and elephantiasis in basidiobolomycosis. (7144812)
1982
28
Elephantiasis nostras. (7353400)
1980
29
The relationship between endemic elephantiasis of the lower legs and the local soils and climate. (4439458)
1974
30
Non-filarial elephantiasis in Ethiopia. Analytical study of inorganic material in lymph nodes. (4339966)
1972
31
A possible genetic factor in non-filarial elephantiasis of the lower legs. (4670473)
1972
32
Elephantiasis nostras streptogenes. (5797977)
1969
33
HISTAMINE CONTENT OF SKIN AFFECTED WITH FILARIAL ELEPHANTIASIS. (14154282)
1964
34
Elephantiasis nostra and elephantiasis tropica: a comparative study. (13877174)
1962
35
The surgical management of elephantiasis of the lower extremities. (13928122)
1962
36
Elephantiasis nostra and elephantiasis tropica. A comparative study. (13877173)
1960
37
Elephantiasis nostra and elephantiasis tropica: a comparative study. (13691391)
1960
38
Neurofibromatosis; a case report of elephantiasis neuromatosa of the right lower extremity, with invasion of the popliteal artery. (13354124)
1956
39
Genital elephantiasis corrected by a plastic procedure. (13233557)
1955
40
Elephantiasis nostra verrucosa; lymphostatic verrucosis. (14360799)
1955
41
Treatment of elephantiasis with cortisone in French Oceania; a preliminary report. (13259018)
1955
42
Elephantiasis nostras; report of a case. (13268541)
1955
43
ELEPHANTIASIS nostras. (13036197)
1953
44
Ptosis with elephantiasis and ectropion. (15425615)
1950
45
The surgical treatment of elephantiasis. (18139103)
1949
46
Syphilid with elephantiasis? (18098646)
1948
47
Microfilarial granulomas, elephantiasis and adenosis of the breast. (20267709)
1947
48
A case of elephantiasis treated by primary skin-grafting. (20283936)
1946
49
THE SURGICAL TREATMENT OF GENITAL ELEPHANTIASIS IN THE MALE. (17866376)
1930
50
"Congenital Elephantiasis" of the Arm. (19975490)
1911

Genetic Variations for Elephantiasis

Expression for genes affiliated with Elephantiasis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Elephantiasis

Search GEO for disease gene expression data for Elephantiasis.

Pathways for genes affiliated with Elephantiasis

Compounds for genes affiliated with Elephantiasis

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB
See all sources

Compounds related to Elephantiasis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1ozone459.7ELN, RNASE3
2n-formylmethionyl-leucylphenylalanine459.6RNASE3, NCF2
3theophylline45 29 11 2412.4ELN, RNASE3
4h2o2459.3ELN, RNASE3, NCF2

GO Terms for genes affiliated with Elephantiasis

Products for genes affiliated with Elephantiasis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Elephantiasis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet