MCID: EMB007
MIFTS: 46

Embryonal Sarcoma malady

Categories: Rare diseases, Fetal diseases, Cancer diseases

Aliases & Classifications for Embryonal Sarcoma

Aliases & Descriptions for Embryonal Sarcoma:

Name: Embryonal Sarcoma 50
Undifferentiated Sarcoma 69

Classifications:



Summaries for Embryonal Sarcoma

MalaCards based summary : Embryonal Sarcoma, also known as undifferentiated sarcoma, is related to undifferentiated embryonal sarcoma of the liver and sarcoma, and has symptoms including fever An important gene associated with Embryonal Sarcoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Glioma and DNA Damage. The drugs Doxorubicin and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include liver, lung and kidney, and related phenotypes are Decreased influenza A/WSN/33 replication and behavior/neurological

Related Diseases for Embryonal Sarcoma

Diseases related to Embryonal Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
id Related Disease Score Top Affiliating Genes
1 undifferentiated embryonal sarcoma of the liver 12.1
2 sarcoma 10.7
3 botryoid rhabdomyosarcoma 10.3 KIT MYOD1
4 blood protein disease 10.3 CDK4 MDM2 SERPINA3
5 isolated anterior cervical hypertrichosis 10.2 SERPINA3 VIM
6 mediastinum rhabdomyosarcoma 10.2 CDK4 MYOD1 MYOG
7 rommen mueller sybert syndrome 10.2 CDK4 MDM2 TP53
8 lupus - neurological sequelae 10.2 S100B VIM
9 acute mountain sickness 10.2 MDM2 TP53
10 heart leiomyosarcoma 10.2 DES MYOG
11 brain stem angioblastoma 10.2 CDK4 MDM2 TP53
12 wolffian adnexal neoplasm 10.2 MKI67 TP53
13 inflammatory linear verrucous epidermal nevus 10.2 DES VIM
14 primary eye hypotony 10.2 CDK4 MDM2
15 interstitial lung disease 10.2 CDK4 MDM2 TP53
16 ossifying fibromyxoid tumor 10.2 CDK4 TP53 VIM
17 stickler syndrome, type i 10.2 CDK4 MDM2 TP53
18 extraocular retinoblastoma 10.2 CDK4 MDM2 TP53
19 malignant adult ependymoma 10.2 SERPINA3 TP53 VIM
20 mixed type rhabdomyosarcoma 10.2 DES MYOD1 MYOG
21 integumentary system benign neoplasm 10.2 CDK4 MDM2 TP53
22 invasive mole 10.2 KIT S100B
23 kidney sarcoma 10.2 MYOD1 MYOG S100B
24 hepatitis 10.2
25 onychocytic matricoma 10.2 S100B SERPINA3 VIM
26 episodic ataxia 10.2 CDK4 DES MDM2
27 post-surgical hypoinsulinemia 10.2 CDK4 MDM2 TP53
28 benign schwannoma 10.2 S100B VIM
29 carbon monoxide-induced parkinsonism 10.2 DES KIT
30 aneurysm of sinus of valsalva 10.2 MDM2 S100B VIM
31 malignant dermis tumor 10.1 DES SERPINA3 VIM
32 multifocal osteogenic sarcoma 10.1 CDK4 KIT MDM2 SERPINA3
33 lymphomatous thyroiditis 10.1 DES VIM
34 urethral cancer 10.1 DES SERPINA3 VIM
35 intracranial sinus thrombosis 10.1 KIT VIM
36 spindle cell rhabdomyosarcoma 10.1 DES MYOD1 MYOG
37 spastic paraplegia 1 10.1 MDM2 MKI67 TP53
38 uterine hypoplasia 10.1 KIT MKI67 VIM
39 focal epithelial hyperplasia 10.1 GPC3 MDM2 SERPINA3
40 human granulocytic anaplasmosis 10.1 KIT TP53 VIM
41 verruciform xanthoma of skin 10.1 DES MYOD1 TP53
42 lung benign neoplasm 10.1 DES MYOD1 VIM
43 vascular myelopathy 10.1 MDM2 S100B TP53
44 stomach diverticulosis 10.1 KIT S100B VIM
45 conjunctival cancer 10.1 S100B TP53 VIM
46 plasmodium ovale malaria 10.1 KIT MKI67 TP53
47 marfanoid hypermobility syndrome 10.1 DES KIT VIM
48 van regemorter pierquin vamos syndrome 10.1 DES KIT MDM2
49 ectodermal dysplasia 10.1 CDK4 MDM2 TP53
50 liver angiosarcoma 10.1 DES KIT VIM

Graphical network of the top 20 diseases related to Embryonal Sarcoma:



Diseases related to Embryonal Sarcoma

Symptoms & Phenotypes for Embryonal Sarcoma

UMLS symptoms related to Embryonal Sarcoma:


fever

GenomeRNAi Phenotypes related to Embryonal Sarcoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased influenza A/WSN/33 replication GR00195-A-1 8.92 AXIN1 CTNNB1 MDM2 MYOD1

MGI Mouse Phenotypes related to Embryonal Sarcoma:

44 (show all 19)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.32 AXIN1 CDK4 CTNNB1 DES KIT MDM2
2 cardiovascular system MP:0005385 10.27 AXIN1 CDK4 CTNNB1 DES GPC3 KIT
3 cellular MP:0005384 10.27 AXIN1 CDK4 CTNNB1 DES GPC3 KIT
4 homeostasis/metabolism MP:0005376 10.25 CDK4 CTNNB1 DES GPC3 KIT MDM2
5 mortality/aging MP:0010768 10.23 MDM2 MYOD1 MYOG PEG3 TP53 VIM
6 growth/size/body region MP:0005378 10.22 AXIN1 CDK4 CTNNB1 GPC3 KIT MDM2
7 embryo MP:0005380 10.19 AXIN1 CDK4 CTNNB1 GPC3 KIT MDM2
8 integument MP:0010771 10.1 CDK4 CTNNB1 GPC3 KIT MDM2 MYOG
9 digestive/alimentary MP:0005381 10.09 AXIN1 CDK4 CTNNB1 GPC3 KIT MDM2
10 muscle MP:0005369 10.09 CDK4 CTNNB1 DES KIT MDM2 MYOD1
11 normal MP:0002873 10.07 AXIN1 CDK4 CTNNB1 KIT MDM2 MKI67
12 craniofacial MP:0005382 10.03 AXIN1 CTNNB1 GPC3 KIT MDM2 TP53
13 limbs/digits/tail MP:0005371 9.95 AXIN1 CTNNB1 GPC3 KIT MDM2 TP53
14 neoplasm MP:0002006 9.88 CDK4 CTNNB1 KIT MDM2 MYOD1 TP53
15 reproductive system MP:0005389 9.85 KIT MDM2 MYOD1 PEG3 TP53 VIM
16 pigmentation MP:0001186 9.8 CDK4 CTNNB1 GPC3 KIT MDM2 TP53
17 renal/urinary system MP:0005367 9.8 AXIN1 CDK4 CTNNB1 GPC3 KIT MDM2
18 respiratory system MP:0005388 9.56 VIM AXIN1 CTNNB1 GPC3 KIT MYOD1
19 skeleton MP:0005390 9.23 GPC3 KIT MDM2 MYOD1 MYOG TP53

Drugs & Therapeutics for Embryonal Sarcoma

Drugs for Embryonal Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 304)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
2
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
3
Etoposide Approved Phase 3,Phase 1,Phase 2 33419-42-0 36462
4
Topotecan Approved, Investigational Phase 3,Phase 2,Phase 1 119413-54-6, 123948-87-8 60700
5
Vinorelbine Approved, Investigational Phase 3,Phase 2,Phase 1 71486-22-1 60780 44424639
6
Carboplatin Approved Phase 3,Phase 1,Phase 2 41575-94-4 10339178 498142 38904
7
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
8
Morphine Approved, Investigational Phase 3,Phase 1,Phase 2 57-27-2 5288826
9
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
10
Mechlorethamine Approved Phase 3,Phase 2,Phase 1 51-75-2 4033
11
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
12
Lenograstim Approved Phase 3,Phase 2,Phase 1 135968-09-1
13
Dactinomycin Approved Phase 3,Phase 2 50-76-0 2019 457193
14
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
15
Irinotecan Approved, Investigational Phase 3,Phase 2,Phase 1 97682-44-5, 100286-90-6 60838
16
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
17
Everolimus Approved Phase 3,Phase 2,Phase 1 159351-69-6 6442177
18 Sodium thiosulfate Approved Phase 3
19
Sirolimus Approved, Investigational Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
20
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
21
Idarubicin Approved Phase 3 58957-92-9 42890
22
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
23
Cyproheptadine Approved Phase 3 129-03-3 2913
24
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
25
Camptothecin Experimental Phase 3,Phase 2,Phase 1 7689-03-4
26 Alkylating Agents Phase 3,Phase 2,Phase 1,Early Phase 1
27 topoisomerase I inhibitors Phase 3,Phase 2,Phase 1
28 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1
29 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
30 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
31 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2,Phase 1
32 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1,Early Phase 1
33 Etoposide phosphate Phase 3,Phase 1,Phase 2
34 Immunoglobulins Phase 3,Phase 1,Phase 2
35 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Early Phase 1
36 Antibodies, Monoclonal Phase 3,Phase 1,Phase 2
37 Immunosuppressive Agents Phase 3,Phase 2,Phase 1,Early Phase 1
38 Protective Agents Phase 3,Phase 2,Phase 1
39 Isophosphamide mustard Phase 3,Phase 2,Phase 1
40 Liver Extracts Phase 3,Phase 2,Phase 1,Early Phase 1
41 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
42 Antibodies Phase 3,Phase 1,Phase 2
43 Antimitotic Agents Phase 3,Phase 2,Phase 1
44 Antirheumatic Agents Phase 3,Phase 2,Phase 1,Early Phase 1
45 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1,Early Phase 1
46 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
47 Podophyllotoxin Phase 3,Phase 2 518-28-5
48 Imatinib Mesylate Phase 2, Phase 3 123596
49 Chelating Agents Phase 3,Phase 2
50 Dermatologic Agents Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 353)
id Name Status NCT ID Phase
1 Stereotactic Body Radiotherapy for Head and Neck Tumors Active, not recruiting NCT01344356 Phase 4
2 Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma Unknown status NCT00379457 Phase 3
3 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Unknown status NCT00346164 Phase 3
4 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
5 Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Completed NCT00002995 Phase 3
6 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3
7 Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma Completed NCT00003958 Phase 3
8 Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor Completed NCT00006734 Phase 3
9 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3
10 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3
11 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3
12 An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation Completed NCT00132704 Phase 3
13 A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families Completed NCT00782145 Phase 3
14 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3
15 Trial for Localised High-risk Rhabdomyosarcoma and Rhabdomyosarcoma-like Soft Tissue Sarcoma Recruiting NCT00876031 Phase 3
16 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3
17 Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma Recruiting NCT02306161 Phase 3
18 Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma Active, not recruiting NCT00075582 Phase 3
19 Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Active, not recruiting NCT00354835 Phase 3
20 Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Active, not recruiting NCT01231906 Phase 3
21 Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer Active, not recruiting NCT01987596 Phase 3
22 Randomized Carbon Ions vs Standard Radiotherapy for Radioresistant Tumors Not yet recruiting NCT02838602 Phase 3
23 Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma Suspended NCT02567435 Phase 3
24 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3
25 Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors Terminated NCT00427583 Phase 2, Phase 3
26 Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma Unknown status NCT00245089 Phase 2
27 Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma Unknown status NCT00245141 Phase 2
28 Antineoplaston Therapy in Treating Patients With Metastatic, Recurrent, or Refractory Primitive Neuroectodermal Tumors Unknown status NCT00003515 Phase 2
29 Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors Unknown status NCT00179816 Phase 1, Phase 2
30 Dendritic Cell Vaccination for Patients With Solid Tumors Unknown status NCT01291420 Phase 1, Phase 2
31 Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients Unknown status NCT01134250 Phase 1, Phase 2
32 Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases Unknown status NCT00084695 Phase 2
33 Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma Unknown status NCT00936052 Phase 2
34 Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation Unknown status NCT00036712 Phase 2
35 Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse Unknown status NCT00180947 Phase 2
36 Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine Unknown status NCT00592748 Phase 1, Phase 2
37 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2
38 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma Completed NCT00031915 Phase 2
39 Chemotherapy in Treating Children With Recurrent or Refractory Sarcomas Completed NCT00003745 Phase 2
40 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma Completed NCT00003955 Phase 2
41 Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors Completed NCT00070109 Phase 2
42 Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma Completed NCT01055314 Phase 2
43 Ixabepilone in Treating Young Patients With Refractory Solid Tumors Completed NCT00331643 Phase 2
44 Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Completed NCT01222715 Phase 2
45 Sorafenib and Dacarbazine in Soft Tissue Sarcoma Completed NCT00837148 Phase 2
46 Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery Completed NCT00004250 Phase 2
47 Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor Completed NCT00055952 Phase 2
48 Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07) Completed NCT00330421 Phase 2
49 A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma Completed NCT00668148 Phase 2
50 Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas Completed NCT00165139 Phase 2

Search NIH Clinical Center for Embryonal Sarcoma

Genetic Tests for Embryonal Sarcoma

Anatomical Context for Embryonal Sarcoma

MalaCards organs/tissues related to Embryonal Sarcoma:

39
Liver, Lung, Kidney, Prostate, Smooth Muscle, Heart, Adrenal Gland

Publications for Embryonal Sarcoma

Articles related to Embryonal Sarcoma:

(show top 50) (show all 152)
id Title Authors Year
1
The Role of Liver Transplantation in Undifferentiated Embryonal Sarcoma of the Liver in Children. ( 27438021 )
2016
2
Characteristics and outcomes in children with undifferentiated embryonal sarcoma of the liver: A report from the National Cancer Database. ( 27781381 )
2016
3
A Case of Ruptured Adult Embryonal Sarcoma of the Liver with Excellent Outcome After Neoadjuvant Chemotherapy. ( 27714652 )
2016
4
Imaging features of undifferentiated embryonal sarcoma of the liver: a series of 15 children. ( 27562247 )
2016
5
Undifferentiated embryonal sarcoma of the liver in an adult patient. ( 27377912 )
2016
6
Undifferentiated Embryonal Sarcoma of the Liver (UESL): A Single-Center Experience and Review of the Literature. ( 26925712 )
2016
7
A single-center experience with undifferentiated embryonal sarcoma of the liver. ( 27427850 )
2016
8
Undifferentiated embryonal sarcoma of the liver in a young female: treatment with portal vein embolization and liver trisectonectomy. ( 27621753 )
2016
9
Erratum to: A Case of Ruptured Adult Embryonal Sarcoma of the Liver with Excellent Outcome After Neoadjuvant Chemotherapy. ( 27796736 )
2016
10
Undifferentiated embryonal sarcoma of the liver with an unusual presentation: case report and review of the literature. ( 27034807 )
2016
11
Adult Embryonal Sarcoma of the Liver: Management of a Massive Liver Tumor. ( 27895954 )
2016
12
Undifferentiated Embryonal Sarcoma of Liver. ( 26788276 )
2015
13
Undifferentiated embryonal sarcoma of the liver: a concise review. ( 25611111 )
2015
14
Pre-operatively misdiagnosed undifferentiated embryonal sarcoma of the liver: analysis of 16 cases. ( 26807408 )
2015
15
Repeated hepatic resections and radio-frequency ablations may improve the survival of adult undifferentiated embryonal sarcoma of the liver: report of two cases. ( 26366352 )
2015
16
Undifferentiated (embryonal) sarcoma of liver. ( 26312248 )
2015
17
Undifferentiated embryonal sarcoma in adult liver. ( 25214865 )
2014
18
A case of an undifferentiated embryonal sarcoma of the liver mimicking a liver abscess. ( 25364566 )
2014
19
Undifferentiated embryonal sarcoma of the liver mistaken for hepatic abscess in an adult. ( 25120683 )
2014
20
Primary undifferentiated embryonal sarcoma of the liver misdiagnosed as hydatid cyst in a child: a case report and review of the literature. ( 25603636 )
2014
21
Mesenchymal hamartoma or embryonal sarcoma of the liver in childhood: a difficult diagnosis before complete surgical excision. ( 25148740 )
2014
22
A Rare Case of Childhood Undifferentiated Embryonal Sarcoma of the Liver Managed Successfully. ( 26157829 )
2014
23
Undifferentiated embryonal sarcoma of liver: a multi-institutional experience with 9 cases. ( 25674229 )
2014
24
Remarkable regression of a lung recurrence from an undifferentiated embryonal sarcoma of the liver treated with a DC vaccine combined with immune cells: a case report. ( 25038546 )
2014
25
Multimodal therapy including liver transplantation for hepatic undifferentiated embryonal sarcoma. ( 24142883 )
2014
26
Diagnosis and therapy of primary undifferentiated embryonal sarcoma of the liver. ( 24762610 )
2014
27
Characterization of translocations in mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver. ( 24120702 )
2013
28
Treatment of undifferentiated embryonal sarcoma of the liver in children--single center experience. ( 24210186 )
2013
29
Undifferentiated embryonal sarcoma of the liver in a child: A case report and review of the literature. ( 23426588 )
2013
30
Management of undifferentiated embryonal sarcoma of the liver in children: a case series and management review. ( 24079623 )
2013
31
Embryonal sarcoma of the liver. ( 23864278 )
2013
32
Undifferentiated embryonal sarcoma of the liver in a middle-aged adult with systemic lupus erythematosus. ( 24073982 )
2013
33
Undifferentiated embryonal sarcoma of the liver with focal osteoid picture-a case report. ( 24054758 )
2013
34
Undifferentiated embryonal sarcoma of the liver in an adult patient: case report. ( 22798120 )
2012
35
Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. ( 21937079 )
2012
36
An undifferentiated embryonal sarcoma of the liver containing adipophilin-positive vesicles in an adult with massive sinusoidal invasion. ( 23071865 )
2012
37
Radiologic-pathologic comparison of undifferentiated embryonal sarcoma of the liver in a 61-year-old woman. ( 22421287 )
2012
38
Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: a case report and literature review. ( 22551002 )
2012
39
Embryonal sarcoma of the liver in an adult patient. ( 22690347 )
2012
40
Rare case of adult undifferentiated (embryonal) sarcoma of the liver treated with liver transplantation: excellent long-term survival. ( 25374706 )
2012
41
A long-term survival case of adult undifferentiated embryonal sarcoma of liver. ( 22540346 )
2012
42
Undifferentiated embryonal sarcoma of the liver is associated with mesenchymal hamartoma and multiple chromosomal abnormalities: a review of eleven cases. ( 20925497 )
2011
43
Undifferentiated embryonal sarcoma of liver in an adult masquerading as complicated hydatid cyst. ( 21301015 )
2011
44
Undifferentiated embryonal sarcoma of the liver presenting as a hemorrhagic cystic tumor in an adult. ( 22146632 )
2011
45
Diffuse membranous immunoreactivity of CD56 and paranuclear dot-like staining pattern of cytokeratins AE1/3, CAM5.2, and OSCAR in undifferentiated (embryonal) sarcoma of the liver. ( 19809302 )
2010
46
Primary undifferentiated embryonal sarcoma of the liver mistaken for hydatid disease. ( 20615265 )
2010
47
Undifferentiated liver embryonal sarcoma in adults: a report of four cases and literature review. ( 20872975 )
2010
48
Undifferentiated embryonal sarcoma: a case report. ( 20207789 )
2010
49
Adult primary undifferentiated embryonal sarcoma of the liver: a case report. ( 20137381 )
2010
50
A case of embryonal sarcoma of the liver. ( 21033305 )
2010

Variations for Embryonal Sarcoma

Expression for Embryonal Sarcoma

Search GEO for disease gene expression data for Embryonal Sarcoma.

Pathways for Embryonal Sarcoma

Pathways related to Embryonal Sarcoma according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.86 AXIN1 CDK4 CTNNB1 KIT MDM2 TP53
2 12.27 CDK4 MDM2 MKI67 TP53 VIM
3
Show member pathways
12.21 AXIN1 CTNNB1 KIT TP53
4 12.16 CTNNB1 GPC3 MDM2 TP53
5 12.12 AXIN1 CDK4 CTNNB1 TP53 VIM
6 12.03 AXIN1 CDK4 CTNNB1 KIT MDM2 TP53
7 11.95 CDK4 CTNNB1 MDM2 TP53
8
Show member pathways
11.91 AXIN1 CTNNB1 KIT MDM2 TP53
9 11.86 CDK4 TP53 VIM
10 11.83 CTNNB1 MDM2 TP53
11 11.73 AXIN1 CTNNB1 MDM2 TP53
12 11.7 CDK4 MDM2 TP53
13 11.62 CTNNB1 MKI67 VIM
14 11.61 CDK4 MDM2 TP53
15 11.54 AXIN1 CTNNB1 MDM2 TP53
16 11.54 DES KIT MYOD1 MYOG
17
Show member pathways
11.48 CTNNB1 MYOD1 MYOG
18 11.33 CDK4 MDM2 TP53
19 11.3 CDK4 MDM2 TP53
20 11.11 CDK4 MDM2 TP53
21 11.07 AXIN1 CDK4 CTNNB1 MDM2 TP53
22 10.85 AXIN1 CTNNB1

GO Terms for Embryonal Sarcoma

Cellular components related to Embryonal Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 nuclear body GO:0016604 9.56 MDM2 MKI67 MYOD1 TP53
2 beta-catenin destruction complex GO:0030877 9.16 AXIN1 CTNNB1
3 fascia adherens GO:0005916 8.96 CTNNB1 DES
4 transcription factor complex GO:0005667 8.92 CDK4 CTNNB1 MYOD1 MYOG

Biological processes related to Embryonal Sarcoma according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.85 AXIN1 CTNNB1 MYOD1 MYOG TP53
2 positive regulation of apoptotic process GO:0043065 9.83 CDK4 CTNNB1 S100B TP53
3 positive regulation of cell proliferation GO:0008284 9.83 CDK4 CTNNB1 KIT MDM2 S100B
4 cellular response to hypoxia GO:0071456 9.67 MDM2 S100B TP53
5 positive regulation of gene expression GO:0010628 9.65 CTNNB1 KIT MDM2 TP53 VIM
6 myoblast differentiation GO:0045445 9.55 MYOD1 MYOG
7 anterior/posterior axis specification GO:0009948 9.54 CTNNB1 GPC3
8 cellular response to growth factor stimulus GO:0071363 9.54 CTNNB1 MDM2 MYOG
9 intermediate filament organization GO:0045109 9.51 DES VIM
10 myotube differentiation GO:0014902 9.48 MYOD1 MYOG
11 positive regulation of skeletal muscle fiber development GO:0048743 9.4 MYOD1 MYOG
12 muscle cell fate commitment GO:0042693 9.32 MYOD1 MYOG
13 cellular response to actinomycin D GO:0072717 9.16 MDM2 TP53
14 positive regulation of muscle cell differentiation GO:0051149 9.13 CTNNB1 MYOD1 MYOG
15 regulation of gene expression GO:0010468 9.02 CDK4 CTNNB1 MDM2 MYOD1 PEG3

Molecular functions related to Embryonal Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 AXIN1 DES MDM2 S100B TP53 VIM
2 ubiquitin protein ligase binding GO:0031625 9.62 AXIN1 MDM2 MYOD1 TP53
3 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228 9.54 MYOD1 MYOG TP53
4 enzyme binding GO:0019899 9.35 AXIN1 CTNNB1 MDM2 MYOD1 TP53
5 I-SMAD binding GO:0070411 9.26 AXIN1 CTNNB1
6 disordered domain specific binding GO:0097718 8.8 CTNNB1 MDM2 TP53

Sources for Embryonal Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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