MCID: ENM002
MIFTS: 27

Enamel Erosion malady

Category: Oral diseases

Aliases & Classifications for Enamel Erosion

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Aliases & Descriptions for Enamel Erosion:

Name: Enamel Erosion 11 13

Classifications:



External Ids:

Disease Ontology11 DOID:2497
ICD9CM32 521.31

Summaries for Enamel Erosion

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MalaCards based summary: Enamel Erosion is related to polyneuropathy in collagen vascular disease and boutonneuse fever. An important gene associated with Enamel Erosion is GPI (Glucose-6-Phosphate Isomerase), and among its related pathways are BRCA1 Pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway. Affiliated tissues include testes.

Related Diseases for Enamel Erosion

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Graphical network of diseases related to Enamel Erosion:



Diseases related to enamel erosion

Symptoms & Phenotypes for Enamel Erosion

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Drugs & Therapeutics for Enamel Erosion

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Drugs for Enamel Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1sodium fluorideapprovedPhase 3, Phase 21937681-49-4
2Anti-Infective AgentsPhase 3, Phase 221402
3Anti-Infective Agents, LocalPhase 3, Phase 21785
4Protective AgentsPhase 3, Phase 27190
5FluorophosphatePhase 358
6ListerinePhase 3, Phase 2193
7Cariostatic AgentsPhase 3, Phase 2318
8FluoridesPhase 3, Phase 2438
9
Mepivacaineapproved, vet_approved5896-88-84062
Synonyms:
(+-)-1-Methyl-2',6'-pipecoloxylidide
1-METHYL-2',6'-PIPECOLOXYLIDIDE
1-methyl-2',6'-pipecoloxylidide
1722-62-9 (mono-hydrochloride)
22801-44-1
34811-66-0
5-22-01-00223 (Beilstein Handbook Reference)
96-88-8
AC-15503
AC1L1HBV
Arestocaine HCL
BRD-A03216249-003-02-9
BRN 0211230
BSPBio_003297
C07528
CHEBI:6759
CHEMBL1087
CID4062
Carbocaine
Carboplyin Dental
Carboplyin Dental (TN)
D(-)-Mepivacaine
D-mepivacaine
D08181
DB00961
DL-Mepivacaine
DivK1c_006970
EINECS 202-543-0
I01-1864
Isocaine HCL
KBio1_001914
KBio2_001960
KBio2_004528
KBio2_007096
 
KBio3_002517
KBioGR_001092
KBioSS_001960
LS-109848
LS-109849
Mepivacaina
Mepivacaina [INN-Spanish]
Mepivacaine (INN)
Mepivacaine HCL
Mepivacaine [INN:BAN]
Mepivacaine hydrochloride
Mepivacainum
Mepivacainum [INN-Latin]
Mepivicaine
MolPort-005-935-383
N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide
N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide
N-Methyl-2-pipecolic acid, 2,6-dimethylanilide
N-Methyl-2-pipecolic acid, 2,6-xylidide
N-Methylhexahydro-2-picolinic acid, 2,6-dimethylanilide
NCGC00089774-02
Polocaine-Mpf
S-Ropivacaine Mesylate
SPBio_001811
Scandicain
Scandicaine
Scandicane
SpecPlus_000874
Spectrum2_001656
Spectrum3_001629
Spectrum4_000596
Spectrum5_001354
Spectrum_001480
UNII-B6E06QE59J
mepivacaine
10Fluorides, Topical52
11Caseins104
12Olaflur6
13Calcium, Dietary5525
14Anesthetics9001

Interventional clinical trials:

(show all 13)
idNameStatusNCT IDPhase
1Effect of Fluoride in a Dentifrice on Remineralization of Erosive LesionsCompletedNCT01641237Phase 3
2Pilot Study Utilising an Impression Technique to Capture in Vivo Images of TeethCompletedNCT02676219Phase 3
3Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental ErosionCompletedNCT01128972Phase 2
4Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ ModelCompletedNCT00752089Phase 2
5Preliminary Clinical Study of Ultrasound to Measure Enamel ThicknessCompletedNCT01622920Phase 1
6In Vivo Investigation of Initial Stages of Enamel ErosionCompletedNCT02533466
7Impact of Milk on Erosion/Abrasion of Enamel and Dentin - an in Situ StudyCompletedNCT01566357
8Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental ErosionCompletedNCT01657903
9Evaluation of a Low-fluoride Anticaries ToothpasteCompletedNCT01094210
10Clinical Comparison of Two Resin Composites on Diastema Closure and Reshaping at Four YearsCompletedNCT02893735
11Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ StudyRecruitingNCT02780973
12Gastro-oesophageal Reflux in Oligosymptomatic Patients With Dental ErosionRecruitingNCT02087345
13NCCL Direct Composite Restoration Performance With Self-Etch and Multimode AdhesivesActive, not recruitingNCT02698371

Search NIH Clinical Center for Enamel Erosion

Genetic Tests for Enamel Erosion

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Anatomical Context for Enamel Erosion

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MalaCards organs/tissues related to Enamel Erosion:

36
Testes

Publications for Enamel Erosion

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Articles related to Enamel Erosion:

(show top 50)    (show all 135)
idTitleAuthorsYear
1
A simple, sensitive and non-destructive technique for characterizing bovine dental enamel erosion: attenuated total reflection Fourier transform infrared spectroscopy. (27025266)
2016
2
Toothpastes and enamel erosion/abrasion- impact of active ingredients and the particulate fraction. (27650640)
2016
3
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. (26964595)
2016
4
Analysis of the Early Stages and Evolution of Dental Enamel Erosion. (27224566)
2016
5
Influence of Calcium Phosphate and Apatite Containing Products on Enamel Erosion. (27430013)
2016
6
In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion. (27020912)
2016
7
A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release. (27121129)
2016
8
In vitro effect of calcium-containing prescription-strength fluoride toothpastes on bovine enamel erosion under hyposalivation-simulating conditions. (25864237)
2015
9
Enamel erosion and mechanical tooth wear in medieval Icelanders. (26358010)
2015
10
Effect of sodium fluoride and stannous chloride associated with Nd:YAG laser irradiation on the progression of enamel erosion. (26227298)
2015
11
Protective effect of casein phosphopeptide-amorphous calcium phosphate on enamel erosion: Atomic force microscopy studies. (25917931)
2015
12
Effect of home-bleaching gels modified by calcium and/or fluoride and the application of nano-hydroxyapatite paste on in vitro enamel erosion susceptibility. (26083582)
2015
13
Sequence of stannous and sodium fluoride solutions to prevent enamel erosion. (26454222)
2015
14
Combined Tin-Containing Fluoride Solution and CO2 Laser Treatment Reduces Enamel Erosion in vitro. (26418736)
2015
15
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. (26092765)
2015
16
In Vitro Effects of Resin Infiltration on Enamel Erosion Inhibition. (25587972)
2015
17
Protective effect of fluoride varnish and fluoride gel on enamel erosion: roughness, SEM-EDS, and A/-EDXRF studies. (25626779)
2015
18
Effect of self-assembling peptide P11 -4 on enamel erosion: AFM and SEM studies. (26435410)
2015
19
COa88 laser emission modes to control enamel erosion. (25988247)
2015
20
Benefits of a dentifrice containing 8% arginine, calcium carbonate, and sodium monofluorophosphate on enamel erosion. (24933796)
2014
21
Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: in vitro study. (24581857)
2014
22
Calcium lactate pre-rinse increased fluoride protection against enamel erosion in a randomized controlled in situ trial. (24582799)
2014
23
Three-dimensional profilometric assessment of early enamel erosion simulating gastric regurgitation. (24995810)
2014
24
A method for monitoring enamel erosion using laser irradiated surfaces and optical coherence tomography. (25147133)
2014
25
Fluoride varnishes containing calcium glycerophosphate: fluoride uptake and the effect on in vitro enamel erosion. (25416637)
2014
26
Enamel erosion--advanced mineralisation technology. Guest foreword. (24993849)
2014
27
Enamel erosion and prevention efficacy characterized by confocal laser scanning microscope. (24706542)
2014
28
Combined effect of a fluoride-, stannous- and chitosan-containing toothpaste and stannous-containing rinse on the prevention of initial enamel erosion-abrasion. (24440712)
2014
29
The CPP-ACP relieved enamel erosion from a carbonated soft beverage: an in vitro AFM and XRD study. (24581849)
2014
30
Measuring initial enamel erosion with quantitative light-induced fluorescence and optical coherence tomography: an in vitro validation study. (24481141)
2014
31
Er:YAG laser irradiation to control the progression of enamel erosion: an in situ study. (24985348)
2014
32
The effect of saliva substitutes on enamel erosion in vitro. (24705070)
2014
33
Potential of CO2 lasers (10.6 A/m) associated with fluorides in inhibiting human enamel erosion. (25337934)
2014
34
Sodium fluoride and casein phosphopeptide-amorphous calcium phosphate cream plus sodium fluoride efficacy in preventing enamel erosion in a simulated oral environment study model. (25307910)
2014
35
In vitro assessment of artificial saliva formulations on initial enamel erosion remineralization. (24269764)
2014
36
Protective effect of CO2 laser (10.6 I1m) and fluoride on enamel erosion in vitro. (22370619)
2013
37
Measuring enamel erosion: a comparative study of contact profilometry, non-contact profilometry and confocal laser scanning microscopy. (24209832)
2013
38
Effect of pretreatment with an Er:YAG laser and fluoride on the prevention of dental enamel erosion. (24149579)
2013
39
Preventive effect of different toothpastes on enamel erosion: AFM and SEM studies. (24374971)
2013
40
Effect of fluoride varnish supplemented with sodium trimetaphosphate on enamel erosion and abrasion. (24640433)
2013
41
The effects of smoothies on enamel erosion: an in situ study. (23909804)
2013
42
Inhibition of enamel erosion by stannous and fluoride containing rinsing solutions. (23519818)
2013
43
Effect of fluoride varnish supplemented with sodium trimetaphosphate on enamel erosion and abrasion: an in situ/ex vivo study. (24095984)
2013
44
In vitro effect of calcium nanophosphate and high-concentrated fluoride agents on enamel erosion: an AFM study. (23782170)
2013
45
Enamel erosion depths measured on impressions by a white light interferometer. (22724578)
2013
46
Protective effect of calcium nanophosphate and CPP-ACP agents on enamel erosion. (24346043)
2013
47
Effect of acidic solution viscosity on enamel erosion. (23315475)
2013
48
Effect of a common diet and regular beverage on enamel erosion in various temperatures: an in-vitro study. (24910648)
2013
49
The effects of fruit smoothies on enamel erosion. (24072423)
2013
50
Inhibition of enamel erosion by stannous fluoride containing rinsing solutions. (23781557)
2013

Variations for Enamel Erosion

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Expression for genes affiliated with Enamel Erosion

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Search GEO for disease gene expression data for Enamel Erosion.

Pathways for genes affiliated with Enamel Erosion

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Pathways related to Enamel Erosion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3SMARCA2, SMARCA4
2
Show member pathways
9.3SMARCA2, SMARCA4

GO Terms for genes affiliated with Enamel Erosion

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Cellular components related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nBAF complexGO:00715659.7SMARCA2, SMARCA4
2npBAF complexGO:00715649.6SMARCA2, SMARCA4
3SWI/SNF complexGO:00165149.3SMARCA2, SMARCA4

Biological processes related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to cadmium ionGO:004668610.1GPI, MTF1
2chromatin remodelingGO:000633810.1SMARCA2, SMARCA4
3negative regulation of cell growthGO:003030810.0SMARCA2, SMARCA4
4positive regulation of transcription, DNA-templatedGO:00458939.5MTF1, SMARCA2, SMARCA4
5regulation of transcription from RNA polymerase II promoterGO:00063579.4MTF1, SMARCA2, SMARCA4
6spermatid developmentGO:00072869.3SMARCA2, SMARCA4

Molecular functions related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1DNA-dependent ATPase activityGO:000809410.0SMARCA2, SMARCA4
2helicase activityGO:00043869.9SMARCA2, SMARCA4
3RNA polymerase II transcription coactivator activityGO:00011059.9SMARCA2, SMARCA4
4transcription coactivator activityGO:00037138.9MTF1, SMARCA2, SMARCA4

Sources for Enamel Erosion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet