MCID: ENM002
MIFTS: 26

Enamel Erosion malady

Category: Oral diseases

Aliases & Classifications for Enamel Erosion

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Aliases & Descriptions for Enamel Erosion:

Name: Enamel Erosion 11 13

Classifications:



External Ids:

Disease Ontology11 DOID:2497
ICD9CM32 521.31

Summaries for Enamel Erosion

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MalaCards based summary: Enamel Erosion is related to eversion of lacrimal punctum and alzheimer's disease 13. An important gene associated with Enamel Erosion is GPI (Glucose-6-Phosphate Isomerase), and among its related pathways are BRCA1 Pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway.

Related Diseases for Enamel Erosion

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Graphical network of diseases related to Enamel Erosion:



Diseases related to enamel erosion

Symptoms & Phenotypes for Enamel Erosion

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Drugs & Therapeutics for Enamel Erosion

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Drugs for Enamel Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1sodium fluorideapprovedPhase 3, Phase 22047681-49-4
2FluorophosphatePhase 360
3Anti-Infective AgentsPhase 3, Phase 222062
4ListerinePhase 3, Phase 2204
5Protective AgentsPhase 3, Phase 27443
6Anti-Infective Agents, LocalPhase 3, Phase 21880
7Cariostatic AgentsPhase 3, Phase 2333
8FluoridesPhase 3, Phase 2462
9
Salicylic acidapproved, vet_approved18969-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004
10
Mepivacaineapproved, vet_approved6596-88-84062
Synonyms:
(+-)-1-Methyl-2',6'-pipecoloxylidide
1-METHYL-2',6'-PIPECOLOXYLIDIDE
1-methyl-2',6'-pipecoloxylidide
1722-62-9 (mono-hydrochloride)
22801-44-1
34811-66-0
5-22-01-00223 (Beilstein Handbook Reference)
96-88-8
AC-15503
AC1L1HBV
Arestocaine HCL
BRD-A03216249-003-02-9
BRN 0211230
BSPBio_003297
C07528
CHEBI:6759
CHEMBL1087
CID4062
Carbocaine
Carboplyin Dental
Carboplyin Dental (TN)
D(-)-Mepivacaine
D-mepivacaine
D08181
DB00961
DL-Mepivacaine
DivK1c_006970
EINECS 202-543-0
I01-1864
Isocaine HCL
KBio1_001914
KBio2_001960
KBio2_004528
KBio2_007096
 
KBio3_002517
KBioGR_001092
KBioSS_001960
LS-109848
LS-109849
Mepivacaina
Mepivacaina [INN-Spanish]
Mepivacaine (INN)
Mepivacaine HCL
Mepivacaine [INN:BAN]
Mepivacaine hydrochloride
Mepivacainum
Mepivacainum [INN-Latin]
Mepivicaine
MolPort-005-935-383
N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide
N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide
N-Methyl-2-pipecolic acid, 2,6-dimethylanilide
N-Methyl-2-pipecolic acid, 2,6-xylidide
N-Methylhexahydro-2-picolinic acid, 2,6-dimethylanilide
NCGC00089774-02
Polocaine-Mpf
S-Ropivacaine Mesylate
SPBio_001811
Scandicain
Scandicaine
Scandicane
SpecPlus_000874
Spectrum2_001656
Spectrum3_001629
Spectrum4_000596
Spectrum5_001354
Spectrum_001480
UNII-B6E06QE59J
mepivacaine
11
Miconazoleapproved, investigational, vet_approved370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
12Caseins108
13Calcium, Dietary5713
14Olaflur6
15Fluorides, Topical54
16Dermatologic Agents5806
17Anesthetics9596
18Keratolytic Agents444
19Antifungal Agents3696

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Effect of Fluoride in a Dentifrice on Remineralization of Erosive LesionsCompletedNCT01641237Phase 3
2Pilot Study Utilising an Impression Technique to Capture in Vivo Images of TeethCompletedNCT02676219Phase 3
3Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental ErosionCompletedNCT01128972Phase 2
4Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ ModelCompletedNCT00752089Phase 2
5Preliminary Clinical Study of Ultrasound to Measure Enamel ThicknessCompletedNCT01622920Phase 1
6In Vivo Investigation of Initial Stages of Enamel ErosionCompletedNCT02533466
7Impact of Milk on Erosion/Abrasion of Enamel and Dentin - an in Situ StudyCompletedNCT01566357
8Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental ErosionCompletedNCT01657903
9Can Surface Roughness Predict Progression of Tooth Wear?CompletedNCT03178968
10Evaluation of a Low-fluoride Anticaries ToothpasteCompletedNCT01094210
11Clinical Comparison of Two Resin Composites on Diastema Closure and Reshaping at Four YearsCompletedNCT02893735
12Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ StudyRecruitingNCT02780973
13Gastro-oesophageal Reflux in Oligosymptomatic Patients With Dental ErosionRecruitingNCT02087345
14Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental ErosionActive, not recruitingNCT03112278
15NCCL Direct Composite Restoration Performance With Self-Etch and Multimode AdhesivesActive, not recruitingNCT02698371

Search NIH Clinical Center for Enamel Erosion

Genetic Tests for Enamel Erosion

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Anatomical Context for Enamel Erosion

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Publications for Enamel Erosion

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Articles related to Enamel Erosion:

(show top 50)    (show all 136)
idTitleAuthorsYear
1
Toothpastes and enamel erosion/abrasion- impact of active ingredients and the particulate fraction. (27650640)
2016
2
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. (26964595)
2016
3
A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release. (27121129)
2016
4
In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion. (27020912)
2016
5
Analysis of the Early Stages and Evolution of Dental Enamel Erosion. (27224566)
2016
6
A simple, sensitive and non-destructive technique for characterizing bovine dental enamel erosion: attenuated total reflection Fourier transform infrared spectroscopy. (27025266)
2016
7
Influence of Calcium Phosphate and Apatite Containing Products on Enamel Erosion. (27430013)
2016
8
Combined Tin-Containing Fluoride Solution and CO2 Laser Treatment Reduces Enamel Erosion in vitro. (26418736)
2015
9
In Vitro Effects of Resin Infiltration on Enamel Erosion Inhibition. (25587972)
2015
10
Protective effect of casein phosphopeptide-amorphous calcium phosphate on enamel erosion: Atomic force microscopy studies. (25917931)
2015
11
COa88 laser emission modes to control enamel erosion. (25988247)
2015
12
Sequence of stannous and sodium fluoride solutions to prevent enamel erosion. (26454222)
2015
13
Effect of home-bleaching gels modified by calcium and/or fluoride and the application of nano-hydroxyapatite paste on in vitro enamel erosion susceptibility. (26083582)
2015
14
Enamel erosion and mechanical tooth wear in medieval Icelanders. (26358010)
2015
15
Effect of sodium fluoride and stannous chloride associated with Nd:YAG laser irradiation on the progression of enamel erosion. (26227298)
2015
16
In vitro effect of calcium-containing prescription-strength fluoride toothpastes on bovine enamel erosion under hyposalivation-simulating conditions. (25864237)
2015
17
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. (26092765)
2015
18
Effect of High-Fluoride Dentifrice on Enamel Erosion Adjacent to Restorations In Vitro. (26266646)
2015
19
Protective effect of fluoride varnish and fluoride gel on enamel erosion: roughness, SEM-EDS, and A/-EDXRF studies. (25626779)
2015
20
Effect of self-assembling peptide P11 -4 on enamel erosion: AFM and SEM studies. (26435410)
2015
21
Er:YAG laser irradiation to control the progression of enamel erosion: an in situ study. (24985348)
2014
22
A method for monitoring enamel erosion using laser irradiated surfaces and optical coherence tomography. (25147133)
2014
23
Fluoride varnishes containing calcium glycerophosphate: fluoride uptake and the effect on in vitro enamel erosion. (25416637)
2014
24
Measuring initial enamel erosion with quantitative light-induced fluorescence and optical coherence tomography: an in vitro validation study. (24481141)
2014
25
Benefits of a dentifrice containing 8% arginine, calcium carbonate, and sodium monofluorophosphate on enamel erosion. (24933796)
2014
26
Calcium lactate pre-rinse increased fluoride protection against enamel erosion in a randomized controlled in situ trial. (24582799)
2014
27
Combined effect of a fluoride-, stannous- and chitosan-containing toothpaste and stannous-containing rinse on the prevention of initial enamel erosion-abrasion. (24440712)
2014
28
Three-dimensional profilometric assessment of early enamel erosion simulating gastric regurgitation. (24995810)
2014
29
The effect of saliva substitutes on enamel erosion in vitro. (24705070)
2014
30
Enamel erosion and prevention efficacy characterized by confocal laser scanning microscope. (24706542)
2014
31
Enamel erosion--advanced mineralisation technology. Guest foreword. (24993849)
2014
32
In vitro assessment of artificial saliva formulations on initial enamel erosion remineralization. (24269764)
2014
33
Sodium fluoride and casein phosphopeptide-amorphous calcium phosphate cream plus sodium fluoride efficacy in preventing enamel erosion in a simulated oral environment study model. (25307910)
2014
34
The CPP-ACP relieved enamel erosion from a carbonated soft beverage: an in vitro AFM and XRD study. (24581849)
2014
35
Potential of CO2 lasers (10.6 A/m) associated with fluorides in inhibiting human enamel erosion. (25337934)
2014
36
Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: in vitro study. (24581857)
2014
37
In vitro effect of calcium nanophosphate and high-concentrated fluoride agents on enamel erosion: an AFM study. (23782170)
2013
38
Protective effect of CO2 laser (10.6 I1m) and fluoride on enamel erosion in vitro. (22370619)
2013
39
Effect of fluoride varnish supplemented with sodium trimetaphosphate on enamel erosion and abrasion: an in situ/ex vivo study. (24095984)
2013
40
Effect of fluoride varnish supplemented with sodium trimetaphosphate on enamel erosion and abrasion. (24640433)
2013
41
Effect of acidic solution viscosity on enamel erosion. (23315475)
2013
42
Inhibition of enamel erosion by stannous and fluoride containing rinsing solutions. (23519818)
2013
43
Effect of pretreatment with an Er:YAG laser and fluoride on the prevention of dental enamel erosion. (24149579)
2013
44
Protective effect of calcium nanophosphate and CPP-ACP agents on enamel erosion. (24346043)
2013
45
Inhibition of enamel erosion by stannous fluoride containing rinsing solutions. (23781557)
2013
46
Effect of a common diet and regular beverage on enamel erosion in various temperatures: an in-vitro study. (24910648)
2013
47
Enamel erosion depths measured on impressions by a white light interferometer. (22724578)
2013
48
The effects of smoothies on enamel erosion: an in situ study. (23909804)
2013
49
Measuring enamel erosion: a comparative study of contact profilometry, non-contact profilometry and confocal laser scanning microscopy. (24209832)
2013
50
Preventive effect of different toothpastes on enamel erosion: AFM and SEM studies. (24374971)
2013

Variations for Enamel Erosion

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Expression for genes affiliated with Enamel Erosion

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Search GEO for disease gene expression data for Enamel Erosion.

Pathways for genes affiliated with Enamel Erosion

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Pathways related to Enamel Erosion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3SMARCA2, SMARCA4
2
Show member pathways
9.3SMARCA2, SMARCA4

GO Terms for genes affiliated with Enamel Erosion

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Cellular components related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nBAF complexGO:00715659.7SMARCA2, SMARCA4
2npBAF complexGO:00715649.6SMARCA2, SMARCA4
3SWI/SNF complexGO:00165149.3SMARCA2, SMARCA4

Biological processes related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to cadmium ionGO:004668610.3GPI, MTF1
2chromatin remodelingGO:000633810.1SMARCA2, SMARCA4
3negative regulation of cell growthGO:003030810.1SMARCA2, SMARCA4
4positive regulation of transcription, DNA-templatedGO:00458939.6MTF1, SMARCA2, SMARCA4
5regulation of transcription from RNA polymerase II promoterGO:00063579.5MTF1, SMARCA2, SMARCA4
6transcription from RNA polymerase II promoterGO:00063668.9MTF1, SMARCA2, SMARCA4

Molecular functions related to Enamel Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1DNA-dependent ATPase activityGO:000809410.0SMARCA2, SMARCA4
2helicase activityGO:000438610.0SMARCA2, SMARCA4
3histone bindingGO:00423939.9SMARCA2, SMARCA4
4hydrolase activity, acting on acid anhydridesGO:00168179.9SMARCA2, SMARCA4
5RNA polymerase II transcription coactivator activityGO:00011059.9SMARCA2, SMARCA4
6transcription coactivator activityGO:00037138.9MTF1, SMARCA2, SMARCA4

Sources for Enamel Erosion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet