MCID: ENC004
MIFTS: 63

Encephalitis malady

Categories: Neuronal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Encephalitis

Summaries for Encephalitis

MedlinePlus : 41 encephalitis is an inflammation of the brain. usually the cause is a viral infection, but bacteria can also cause it. it can be mild or severe. most cases are mild. you may have flu-like symptoms. with a mild case, you may just need rest, plenty of fluids, and a pain reliever. severe cases need immediate treatment. symptoms of severe cases include severe headache sudden fever drowsiness vomiting confusion seizures in babies, additional symptoms may include constant crying, poor feeding, body stiffness, and bulging in the soft spots of the skull. severe cases may require a stay in the hospital. treatments include oral and intravenous (iv) medicines to reduce inflammation and treat infection. patients with breathing difficulties may need artificial respiration. some people may need physical, speech, and occupational therapy once the illness is under control. nih: national institute of neurological disorders and stroke

MalaCards based summary : Encephalitis is related to status epilepticus and hepatitis c virus, and has symptoms including back pain, headache and pain. An important gene associated with Encephalitis is CD209 (CD209 Molecule), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Azithromycin and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Disease Ontology : 12 A brain disease that is characterized as an acute inflammation of the brain with flu-like symptoms.

NINDS : 51 Meningitis is an infection of the meninges, the membranes that surround the brain and spinal cord. Encephalitis is inflammation of the brain itself. Causes of encephalitis and meningitis include viruses, bacteria, fungus, and parasites. Anyone can get encephalitis or meningitis.Inflammation from encephalitis and meningitis produce a wide range of symptoms.  Symptoms of encephalitis include sudden fever, headache, vomiting, heightened sensitivity to light, stiff neck and back, confusion and impaired judgment, drowsiness, weak muscles, a clumsy and unsteady gait, and irritability. In more severe cases, people may have problems with speech or hearing, vision problems, and hallucinations. Symptoms that might require emergency treatment include loss of consciousness, seizures, muscle weakness, or sudden severe dementia.

Wikipedia : 71 Encephalitis is a sudden onset inflammation of the brain. Encephalitis with meningitis is known as... more...

Related Diseases for Encephalitis

Diseases in the Encephalitis family:

Viral Encephalitis Autoimmune Encephalitis

Diseases related to Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 525)
id Related Disease Score Top Affiliating Genes
1 status epilepticus 30.2 CCL2 CCL5 CXCL10 IL1B
2 hepatitis c virus 28.8 CCR5 CD209 CLEC4M DDX58 IRF3 RSAD2
3 japanese encephalitis 12.4
4 tick-borne encephalitis 12.4
5 la crosse encephalitis 12.3
6 st. louis encephalitis 12.3
7 herpes simplex encephalitis 12.2
8 limbic encephalitis 12.2
9 eastern equine encephalitis 12.2
10 viral encephalitis 12.2
11 murray valley encephalitis 12.2
12 rasmussen encephalitis 12.2
13 granulomatous amebic encephalitis 12.1
14 west nile encephalitis 12.1
15 autoimmune encephalitis 12.1
16 hashimoto's encephalitis 12.1
17 venezuelan equine encephalitis 12.1
18 hhv-6 encephalitis 12.1
19 powassan encephalitis 12.1
20 meningitis and encephalitis 12.1
21 western equine encephalitis 12.0
22 herpes simplex encephalitis 1 12.0
23 bickerstaff brainstem encephalitis 12.0
24 herpes simplex encephalitis 2 12.0
25 herpes simplex encephalitis 3 11.9
26 von economo's disease 11.9
27 herpes simplex encephalitis 7 11.9
28 post-vaccinal encephalitis 11.8
29 kunjin encephalitis 11.8
30 acute necrotizing encephalitis 11.8
31 acute hemorrhagic encephalitis 11.8
32 rasmussen subacute encephalitis 11.8
33 nipah virus encephalitis 11.7
34 non-herpetic acute limbic encephalitis 11.7
35 rheumatic encephalitis 11.7
36 mycoplasma encephalitis 11.7
37 posttransplant acute limbic encephalitis 11.7
38 acute disseminated encephalomyelitis 11.7
39 limbic encephalitis with dpp6 antibodies 11.7
40 limbic encephalitis with nmda receptor antibodies 11.6
41 classic paraneoplastic limbic encephalitis 11.6
42 syphilitic encephalitis 11.6
43 limbic encephalitis with lgi1 antibodies 11.6
44 limbic encephalitis with ncmags antibodies 11.6
45 west nile virus 11.6
46 limbic encephalitis with caspr2 antibodies 11.6
47 panencephalitis, subacute sclerosing 11.5
48 meningitis 11.3
49 febrile infection-related epilepsy syndrome 11.3
50 meningoencephalitis 11.3

Graphical network of the top 20 diseases related to Encephalitis:



Diseases related to Encephalitis

Symptoms & Phenotypes for Encephalitis

UMLS symptoms related to Encephalitis:


back pain, headache, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness

MGI Mouse Phenotypes related to Encephalitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.21 CCL5 CCR5 CLEC4G CLEC4M CXCL10 DDX58
2 homeostasis/metabolism MP:0005376 10.2 TICAM1 TLR3 TRAF3 TREX1 UNC93B1 CCR5
3 immune system MP:0005387 10.16 TICAM1 TLR3 TRAF3 TREX1 UNC93B1 CCL2
4 cardiovascular system MP:0005385 10.06 CCR5 CXCL10 GFAP IL1B RPSA SCRIB
5 mortality/aging MP:0010768 9.77 CCR5 CLEC4M CXCL10 DDX58 GFAP IL1B
6 liver/biliary system MP:0005370 9.7 CLEC4G DDX58 TICAM1 TRAF3 TREX1 UNC93B1
7 neoplasm MP:0002006 9.1 CCR5 DDX58 IL1B SCRIB TICAM1 TLR3

Drugs & Therapeutics for Encephalitis

Drugs for Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 212)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 1 83905-01-5 55185 53477736 447043
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3
Ethanol Approved Phase 4 64-17-5 702
4
Formaldehyde Approved, Vet_approved Phase 4,Phase 3 50-00-0 712
5
Minocycline Approved, Investigational Phase 4,Phase 1 10118-90-8 5281021
6
Sulfadiazine Approved, Vet_approved Phase 4,Phase 2 68-35-9 5215
7
Sulfamethoxazole Approved Phase 4 723-46-6 5329
8
Pyrimethamine Approved, Vet_approved Phase 4,Phase 2,Phase 1 58-14-0 4993
9
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
10
Natalizumab Approved, Investigational Phase 4 189261-10-7
11
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
12
Dimenhydrinate Approved Phase 4 523-87-5 441281
13
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
14
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
15
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 1 58-05-9 54575, 6560146 143
16
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 1 59-30-3 6037
17 glucocorticoids Phase 4,Phase 3
18 Hormone Antagonists Phase 4,Phase 3,Phase 2
19 Hormones Phase 4,Phase 3,Phase 2
20 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
21 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
22 Immunoglobulins Phase 4,Phase 2,Phase 3,Phase 1
23 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
25 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
26 Antibodies Phase 4,Phase 2,Phase 3,Phase 1
27 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
28
Lactitol Phase 4,Phase 3,Phase 2 585-86-4 3871
29 Folic Acid Antagonists Phase 4,Phase 2,Phase 1
30 Gastrointestinal Agents Phase 4,Phase 3,Phase 1
31 Heptavalent Pneumococcal Conjugate Vaccine Phase 4,Phase 3
32 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4
33 Disinfectants Phase 4,Phase 3
34 Vitamin B Complex Phase 4,Phase 2,Phase 1
35 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2
36 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Antimalarials Phase 4,Phase 3,Phase 2,Phase 1
38 Antibiotics, Antitubercular Phase 4,Phase 3
39 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
40 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Epoetin alfa Phase 4 113427-24-0
42 Hematinics Phase 4
43 Peripheral Nervous System Agents Phase 4,Phase 3
44 Vasoconstrictor Agents Phase 4
45 Epinephryl borate Phase 4
46 Antiemetics Phase 4,Phase 3
47 Racepinephrine Phase 4
48 Autonomic Agents Phase 4,Phase 3
49 Prednisolone acetate Phase 4
50 Neuromuscular Blocking Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 269)
id Name Status NCT ID Phase
1 Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Unknown status NCT01954810 Phase 4
2 Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine Unknown status NCT01398540 Phase 4
3 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4
4 A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2 Completed NCT01656200 Phase 4
5 Long-term Immunogenicity and Safety of Fourth Administration of Boryung Cell-Culture Japanese Encephalitis Vaccineinj Completed NCT02532569 Phase 4
6 Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAX Completed NCT02526550 Phase 4
7 Immunogenicity of Co-administration of Measles and Japanese Encephalitis Vaccines Completed NCT02643433 Phase 4
8 TBE Antibody Persistence and Booster Vaccination Study in Children and Adolescents (Follow-up to Study 209) Completed NCT00161967 Phase 4
9 Study to Evaluate Long Term Immunogenicity up to 10 Years After the First Booster Immunization With Tick Borne Encephalitis Vaccine in Adults Who Received 1 of 3 Different Primary Vaccination Schedules Completed NCT01562444 Phase 4
10 6-year Antibody Check After Third Vaccination Against Japanese Encephalitis Completed NCT02039440 Phase 4
11 An Extension Study to Determine the Persistence of Tick-borne Encephalitis (TBE)-Specific Antibody Responses Among Children and Adolescents Previously Immunized Against TBE Completed NCT01106482 Phase 4
12 Long-term Immunogenicity After Receipt of JE Vaccine and Antibody Response and Safety to a Booster Dose Completed NCT02514746 Phase 4
13 TBE Antibody Persistence and Booster Vaccination Study in Adults (Follow-up to Study 223) Completed NCT00503529 Phase 4
14 This is a Study to Assess the Safety and Immunogenicity of Ixiaro® (IC51) in an Elderly Population Completed NCT01158599 Phase 4
15 Treatment of Cerebral Toxoplasmosis in HIV/AIDS Completed NCT00367081 Phase 4
16 Immunogenicity and Safety Study of a Rapid Immunization Schedule With FSME-IMMUN 0.5 mL in Healthy Adults Aged 16 - 65 Years Completed NCT00161954 Phase 4
17 Cervicovaginal Immune Responses to 3 Deltoid or Thigh Intramuscular (IM) TicoVac Completed NCT01710189 Phase 4
18 Post-licensure Safety Study of IMOJEV® in Thailand Completed NCT01981967 Phase 4
19 Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination Completed NCT00804219 Phase 4
20 Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults Completed NCT00311493 Phase 4
21 Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children Completed NCT00311441 Phase 4
22 Lot-to-lot Consistency Trial of JE Live Attenuated SA 14-14-2 Vaccine Completed NCT01567865 Phase 4
23 TBE Seropersistence up to 10 Years After First Booster in Adults Completed NCT01582698 Phase 4
24 Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children Completed NCT00163618 Phase 4
25 Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225) Completed NCT00163540 Phase 4
26 Safety and Long-term Evaluation (up to 5 Years) of First Booster Immunization With Novartis' TBE Vaccine for Adults in Adolescents and Adults Completed NCT00387634 Phase 4
27 Influence of Persistent CMV-infection on Immune Senescence Completed NCT00461695 Phase 4
28 Evaluation of Long-Term Immunogenicity in Children and Adolescents Boosted With a New Pediatric TBE Vaccine After Five Years Completed NCT00452621 Phase 4
29 Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years Completed NCT00161785 Phase 4
30 Immunogenicity of SA 14-14-2 JE Vaccine Completed NCT01635816 Phase 4
31 Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE Vaccine Completed NCT01815073 Phase 4
32 Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events Completed NCT01417949 Phase 4
33 Study of Evaluating Safety and Immunogenicity of 23-Valent Pneumococcal Polysaccharide Vaccine With Influenza Vaccine in Children and Adults Completed NCT02062281 Phase 4
34 Minocycline to Treat Childhood Regressive Autism Completed NCT00409747 Phase 4
35 Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age Completed NCT01985997 Phase 4
36 Kaiser Permanente HIV Cohort Study Completed NCT01339403 Phase 4
37 Effect of Erythropoietin in Refractory Autoimmune Encephalitis Patients Recruiting NCT03004209 Phase 4
38 Postmarketing Surveillance Study for IMOJEV® in Republic of Korea Recruiting NCT02933710 Phase 4
39 Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella Vaccine Recruiting NCT02880865 Phase 4
40 SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies Recruiting NCT02951559 Phase 4
41 TBE Vaccination in Allergic Patients Recruiting NCT02511535 Phase 4
42 Tick-Borne Encephalitis (TBE) Seropersistence After First Booster in Children, Adolescents and Young Adults (Follow-Up to Study 700401) Active, not recruiting NCT00894686 Phase 4
43 Safety and Effectiveness of Switching Relapsing MS Patients Treated With Natalizumab at Risk for PML to Teriflunomide Active, not recruiting NCT01970410 Phase 4
44 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
45 Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS) Terminated NCT01211665 Phase 4
46 Efficacy of Tacrolimus and I.V.-Immunoglobulins in Rasmussen Encephalitis Unknown status NCT00545493 Phase 2, Phase 3
47 Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR Unknown status NCT00938379 Phase 3
48 Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in Toddlers Completed NCT01396512 Phase 3
49 A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers Completed NCT01092507 Phase 3
50 Long-term Follow-up of Immunogenicity of a Single Dose of Japanese Encephalitis Chimeric Virus Vaccine in Toddlers Completed NCT01001988 Phase 3

Search NIH Clinical Center for Encephalitis

Cochrane evidence based reviews: encephalitis

Genetic Tests for Encephalitis

Genetic tests related to Encephalitis:

id Genetic test Affiliating Genes
1 Encephalitis 29

Anatomical Context for Encephalitis

MalaCards organs/tissues related to Encephalitis:

39
Brain, T Cells, Testes, Spinal Cord, Lung, Temporal Lobe, B Cells

Publications for Encephalitis

Articles related to Encephalitis:

(show top 50) (show all 5536)
id Title Authors Year
1
Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Risk of Neuroleptic Malignant Syndrome. ( 27836566 )
2017
2
Relapsing Polychondritis Presented with Encephalitis Followed by Brain Atrophy. ( 28243168 )
2017
3
Ablation of Programmed -1 Ribosomal Frameshifting in Venezuelan Equine Encephalitis Virus Results in Attenuated Neuropathogenicity. ( 27852852 )
2017
4
Teratoma-associated NMDAr encephalitis: management considerations. ( 28012265 )
2017
5
Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa. ( 28402771 )
2017
6
Introducing a cleavable signal peptide enhances the packaging efficiency of lentiviral vectors pseudotyped with Japanese encephalitis virus envelope proteins. ( 27993624 )
2017
7
Antisense Oligonucleotides Targeting Raf-1 Block Japanese Encephalitis Virus In Vitro and In Vivo. ( 28051352 )
2017
8
Altered mitochondrial dynamics as a consequence of Venezuelan Equine Encephalitis Virus infection. ( 28075229 )
2017
9
Immunogenicity of a Live Attenuated Chimeric Japanese Encephalitis Vaccine as a Booster Dose After Primary Vaccination With Live Attenuated SA14-14-2 Vaccine: A Phase IV Study in Thai Children. ( 27846060 )
2017
10
Human Tick-Borne Encephalitis, the Netherlands. ( 27938522 )
2017
11
European Aedes albopictus and Culex pipiens are Competent Vectors for Japanese Encephalitis Virus. ( 28085881 )
2017
12
How Zoophilic Japanese Encephalitis Vector Mosquitoes Feed on Humans. ( 28082626 )
2017
13
Pure word deafness due to herpes simplex encephalitis. ( 28017194 )
2017
14
Toxicity of ar-curcumene and epi-I^-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors. ( 27918946 )
2017
15
Anti-N-methyl-D-aspartate receptor(NMDAR) antibody encephalitis presents in atypical types and coexists with neuromyelitis optica spectrum disorder or neurosyphilis. ( 28056870 )
2017
16
Dual infection with Japanese encephalitis and dengue fever: Issues with diagnosis. ( 28084252 )
2017
17
Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis. ( 28045967 )
2017
18
Anesthesia management of cesarean section in parturient with anti-N-methyl-D-aspartate receptor encephalitis: a case report. ( 28070654 )
2017
19
Deep sequencing analysis of tick-borne encephalitis virus from questing ticks at natural foci reveals similarities between quasispecies pools of the virus. ( 28073402 )
2017
20
Mx Is Not Responsible for the Antiviral Activity of Interferon-I+ against Japanese Encephalitis Virus. ( 28075421 )
2017
21
Seasonality of Viral Encephalitis and Associated Environmental Risk Factors in Son La and Thai Binh Provinces in Vietnam from 2004 to 2013. ( 27799646 )
2017
22
COMPARISON BETWEEN PROTON MAGNETIC RESONANCE SPECTROSCOPY FINDINGS IN DOGS WITH TICK-BORNE ENCEPHALITIS AND CLINICALLY NORMAL DOGS. ( 27714889 )
2017
23
Travel-Related Tick-Borne Encephalitis, Israel, 2006-2014. ( 27779467 )
2017
24
Progressive hearing loss and cerebellar ataxia in anti-Ma2-associated autoimmune encephalitis. ( 28099568 )
2017
25
Emergence of new-onset psychotic disorder following recovery from LGI1 antibody-associated limbic encephalitis. ( 28363946 )
2017
26
Epstein-Barr Virus-associated Lymphoproliferative Disorder with Encephalitis Following Anti-thymocyte Globulin for Aplastic Anemia Resolved with Rituximab Therapy: A Case Report and Literature Review. ( 28321074 )
2017
27
Post-licensure, phase IV, safety study of a live attenuated Japanese encephalitis recombinant vaccine in children in Thailand. ( 27903416 )
2017
28
GRP78 is an important host-factor for Japanese encephalitis virus entry and replication in mammalian cells. ( 28053106 )
2017
29
Characteristics in limbic encephalitis with anti-adenylate kinase 5 autoantibodies. ( 28062719 )
2017
30
Interactions of human microglia cells with Japanese encephalitis virus. ( 28088249 )
2017
31
Tick-borne encephalitis virus neutralization by high dose intravenous immunoglobulin. ( 27884572 )
2017
32
Absence of system xc(-) on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis. ( 28086920 )
2017
33
Herpes Simplex Encephalitis Complicated by Cerebral Hemorrhage during Acyclovir Therapy. ( 28090058 )
2017
34
Demyelinating polyneuropathy in a case of anti-LGI1 encephalitis. ( 28073143 )
2017
35
Cyclic patterns in the central European tick-borne encephalitis incidence series. ( 27772539 )
2017
36
Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: systematic review and meta-analysis. ( 28090819 )
2017
37
Scrub Typhus Leading to Acute Encephalitis Syndrome, Assam, India. ( 27875108 )
2017
38
Diagnostic dilemma-dengue or Japanese encephalitis? ( 28084251 )
2017
39
Inhibition of Japanese encephalitis virus (JEV) replication by specific RNA aptamer against JEV methyltransferase. ( 27986564 )
2017
40
Herpes Simplex Encephalitis. ( 28076016 )
2017
41
Rasmussen Encephalitis. ( 28042372 )
2017
42
Incidence and mortality of herpes simplex encephalitis in Denmark: A nationwide registry-based cohort study. ( 27717782 )
2017
43
The long-term neuropsychological features of basal ganglia encephalitis. ( 28084620 )
2017
44
Do we need to measure specific antibodies in patients with limbic encephalitis? ( 28062718 )
2017
45
Thiosemicarbazones and Phthalyl-Thiazoles compounds exert antiviral activity against yellow fever virus and Saint Louis encephalitis virus. ( 28068627 )
2017
46
MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1. ( 26819305 )
2016
47
Rasmussen encephalitis tissue transfer program. ( 27286752 )
2016
48
The major histocompatibility complex and antibody-mediated limbic encephalitis. ( 28026032 )
2016
49
Editorial: Limbic Encephalitis: Autoimmune Impact on Inhibitory GABAergic Neuronal Pathways in Temporal Lobe Epilepsy. ( 27014186 )
2016
50
Interleukin-6 Blockade as Rescue Therapy in Autoimmune Encephalitis. ( 27530677 )
2016

Variations for Encephalitis

Expression for Encephalitis

Search GEO for disease gene expression data for Encephalitis.

Pathways for Encephalitis

Pathways related to Encephalitis according to GeneCards Suite gene sharing:

(show all 25)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.92 CCL2 CCL5 CCR5 CD209 CXCL10 DDX58
2
Show member pathways
13.31 CCL2 CCL5 CCR5 CXCL10 CXCL9 IL1B
3
Show member pathways
13.27 CCL2 CCL5 CCR5 CXCL10 DDX58 IL1B
4
Show member pathways
12.84 CCL2 CCL5 CD209 IL1B IRF3 TICAM1
5
Show member pathways
12.77 CCL2 CCL5 CCR5 CXCL10 CXCL9
6
Show member pathways
12.63 CCL2 CCL5 CXCL10 CXCL9 DDX58 IL1B
7
Show member pathways
12.55 CCL5 CXCL10 DDX58 IL1B IRF3 TRAF3
8
Show member pathways
12.35 DDX58 IRF3 TICAM1 TLR3 TREX1
9
Show member pathways
12.22 CCL2 CXCL10 IL1B TRAF3
10 12.19 CCR5 IRF3 SCRIB TRAF3
11
Show member pathways
12.15 IRF3 TICAM1 TLR3 TRAF3
12 12.15 CCL2 CCL5 CXCL10 DDX58 IL1B IRF3
13
Show member pathways
12.09 CCL2 CCL5 CD209 CLEC4M CXCL10 DDX58
14 11.97 DDX58 IRF3 TICAM1 TLR3 TRAF3
15 11.93 CCL2 CXCL10 GFAP IL1B
16
Show member pathways
11.92 CCL2 CCL5 CCR5 CXCL10 CXCL9
17 11.8 DDX58 IL1B TICAM1 TRAF3
18 11.75 CCL2 CCL5 CXCL10 IL1B TRAF3
19 11.74 CCL2 CCL5 IL1B
20 11.66 IL1B IRF3 TICAM1
21 11.55 CCL2 CCL5 IL1B
22 11.34 CCL2 CCL5 CCR5 CXCL10 IL1B
23 11.3 CXCL10 CXCL9 IL1B
24 11.12 CCL2 CCL5 CXCL10 CXCL9 IL1B
25 10.82 CCL2 IL1B

GO Terms for Encephalitis

Cellular components related to Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.8 CCL2 CCL5 CCR5 CD209 CLEC4M DDX58
2 external side of plasma membrane GO:0009897 8.92 CCR5 CD209 CXCL10 CXCL9

Biological processes related to Encephalitis according to GeneCards Suite gene sharing:

(show top 50) (show all 57)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.97 CCL2 CCL5 CCR5 CXCL10 CXCL9 IL1B
2 innate immune response GO:0045087 9.97 CD209 CLEC4M DDX58 IRF3 RSAD2 TICAM1
3 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.95 IL1B IRF3 TICAM1 TLR3
4 chemotaxis GO:0006935 9.95 CCL2 CCL5 CCR5 CXCL10 CXCL9
5 response to lipopolysaccharide GO:0032496 9.93 CCL2 CXCL10 CXCL9 IL1B IRF3 TICAM1
6 cellular response to lipopolysaccharide GO:0071222 9.92 CCL2 CCR5 CXCL10 IRF3 TICAM1
7 response to virus GO:0009615 9.89 CCL5 CXCL10 DDX58 RSAD2 TLR3
8 cellular response to organic cyclic compound GO:0071407 9.88 CCL2 CCL5 IL1B
9 viral entry into host cell GO:0046718 9.88 CD209 CLEC4G CLEC4M RPSA
10 cellular response to drug GO:0035690 9.87 CCL2 IL1B TLR3
11 cell chemotaxis GO:0060326 9.87 CCL2 CCL5 CXCL10
12 neutrophil chemotaxis GO:0030593 9.86 CCL2 CCL5 IL1B
13 cellular response to interferon-gamma GO:0071346 9.86 CCL2 CCL5 TLR3
14 positive regulation of type I interferon production GO:0032481 9.85 IRF3 TICAM1 TLR3
15 positive regulation of tumor necrosis factor production GO:0032760 9.82 CCL2 TICAM1 TLR3
16 toll-like receptor signaling pathway GO:0002224 9.81 TLR3 TRAF3 UNC93B1
17 positive regulation of interleukin-6 production GO:0032755 9.81 DDX58 IL1B TICAM1 TLR3
18 immune system process GO:0002376 9.81 CD209 CLEC4M DDX58 IRF3 RSAD2 TICAM1
19 negative regulation of type I interferon production GO:0032480 9.8 DDX58 IRF3 TRAF3
20 protein kinase B signaling GO:0043491 9.8 CCL2 CCL5 IL1B
21 chemokine-mediated signaling pathway GO:0070098 9.8 CCL2 CCL5 CCR5 CXCL10 CXCL9
22 response to exogenous dsRNA GO:0043330 9.78 DDX58 IRF3 TICAM1 TLR3
23 positive regulation of interferon-beta production GO:0032728 9.77 DDX58 IRF3 TLR3
24 positive regulation of interleukin-8 production GO:0032757 9.77 DDX58 IL1B TLR3
25 leukocyte cell-cell adhesion GO:0007159 9.76 CCL5 CD209 CLEC4M
26 positive regulation of monocyte chemotaxis GO:0090026 9.74 CCL2 CCL5 CXCL10
27 viral genome replication GO:0019079 9.73 CCL2 CD209 CLEC4M
28 TRIF-dependent toll-like receptor signaling pathway GO:0035666 9.73 IRF3 TICAM1 TLR3 TRAF3
29 regulation of type I interferon production GO:0032479 9.72 IRF3 TREX1
30 dendritic cell chemotaxis GO:0002407 9.72 CCL5 CCR5
31 necroptotic process GO:0070266 9.72 TICAM1 TLR3
32 positive regulation of macrophage chemotaxis GO:0010759 9.72 CCL2 CCL5
33 macrophage chemotaxis GO:0048246 9.71 CCL2 CCL5
34 positive regulation of T cell migration GO:2000406 9.71 CCL5 CXCL10
35 MyD88-independent toll-like receptor signaling pathway GO:0002756 9.71 TICAM1 TLR3
36 positive regulation of interferon-alpha production GO:0032727 9.71 DDX58 IRF3
37 positive regulation of chemokine biosynthetic process GO:0045080 9.71 IL1B TICAM1 TLR3
38 positive regulation of cAMP-mediated signaling GO:0043950 9.7 CXCL10 CXCL9
39 T cell chemotaxis GO:0010818 9.7 CXCL10 CXCL9
40 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.7 DDX58 IL1B
41 toll-like receptor 3 signaling pathway GO:0034138 9.68 TLR3 UNC93B1
42 negative regulation of MyD88-independent toll-like receptor signaling pathway GO:0034128 9.68 TICAM1 TLR3
43 modulation by virus of host morphology or physiology GO:0019048 9.68 CD209 CLEC4M
44 positive regulation of interferon-beta biosynthetic process GO:0045359 9.67 TICAM1 TLR3
45 positive regulation of cAMP metabolic process GO:0030816 9.67 CXCL10 CXCL9
46 cellular response to dsRNA GO:0071359 9.66 IRF3 TLR3
47 astrocyte cell migration GO:0043615 9.66 CCL2 SCRIB
48 cell-cell recognition GO:0009988 9.65 CD209 CLEC4M
49 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 CCL2 CCL5 IL1B IRF3 TICAM1
50 detection of virus GO:0009597 9.64 DDX58 TLR3

Molecular functions related to Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.55 CCL2 CCL5 CXCL10 CXCL9 IL1B
2 mannose binding GO:0005537 9.37 CD209 CLEC4M
3 virion binding GO:0046790 9.32 CD209 CLEC4M
4 CXCR3 chemokine receptor binding GO:0048248 9.26 CXCL10 CXCL9
5 chemokine activity GO:0008009 9.26 CCL2 CCL5 CXCL10 CXCL9
6 virus receptor activity GO:0001618 9.02 CCR5 CD209 CLEC4G CLEC4M RPSA

Sources for Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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