MCID: ENC036
MIFTS: 23

Encephalopathy, Acute, Infection-Induced, 4 malady

Categories: Genetic diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Encephalopathy, Acute, Infection-Induced, 4

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Aliases & Descriptions for Encephalopathy, Acute, Infection-Induced, 4:

Name: Encephalopathy, Acute, Infection-Induced, 4 51 69
Encephalopathy, Acute, Infection-Induced, Susceptibility to, 4 51
Acute Necrotizing Encephalopathy of Childhood 53
Isolated Acute Necrotizing Encephalopathy 53
Encephalopathy Acute Infection-Induced 4 69
 
Encephalitis, Viral 38
Isolated Ane 53
Iiae4 69
Anec 53

Characteristics:

Orphanet epidemiological data:

53
acute necrotizing encephalopathy of childhood:
Inheritance: Not applicable; Age of onset: Childhood

HPO:

63
encephalopathy, acute, infection-induced, 4:
Inheritance: autosomal dominant inheritance, autosomal recessive inheritance

Classifications:



External Ids:

OMIM51 614212
Orphanet53 ORPHA263524
ICD10 via Orphanet30 G31.8
MedGen36 C3280160
MeSH38 D018792
ICD1029 A86, A85.8

Summaries for Encephalopathy, Acute, Infection-Induced, 4

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OMIM:51 Acute encephalopathy is a severe neurologic complication of an infection that usually occurs in children. It is... (614212) more...

MalaCards based summary: Encephalopathy, Acute, Infection-Induced, 4, also known as encephalopathy, acute, infection-induced, susceptibility to, 4, is related to viral encephalitis and infection-induced acute encephalopathy 4, susceptibility, and has symptoms including seizures, coma and encephalopathy. An important gene associated with Encephalopathy, Acute, Infection-Induced, 4 is CPT2 (Carnitine Palmitoyltransferase 2). Affiliated tissues include brain.

UniProtKB/Swiss-Prot:69 Encephalopathy, acute, infection-induced, 4: A severe neurologic complication of an infection. It manifests within days in otherwise healthy children after common viral infections, without evidence of viral infection of the brain or inflammatory cell infiltration. In affected children, high-grade fever is accompanied within 12 to 48 hours by febrile convulsions, often leading to coma, multiple-organ failure, brain edema, and high morbidity and mortality. The infections are usually viral, particularly influenza, although other viruses and even mycoplasma have been found to cause the disorder.

Related Diseases for Encephalopathy, Acute, Infection-Induced, 4

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Diseases related to Encephalopathy, Acute, Infection-Induced, 4 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1viral encephalitis11.5
2infection-induced acute encephalopathy 4, susceptibility11.4
3herpes simplex encephalitis 110.9
4question mark ears, isolated10.4
5encephalitis10.2
6japanese encephalitis9.9
7st. louis encephalitis9.9
8meningitis and encephalitis9.8
9encephalopathy9.8
10myelitis9.6
11venezuelan equine encephalitis9.6
12transverse myelitis9.6
13acute transverse myelitis9.6
14paralytic poliomyelitis9.2
15herpes simplex9.2
16candida glabrata9.2

Graphical network of diseases related to Encephalopathy, Acute, Infection-Induced, 4:



Diseases related to encephalopathy, acute, infection-induced, 4

Symptoms for Encephalopathy, Acute, Infection-Induced, 4

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Symptoms by clinical synopsis from OMIM:

614212

Clinical features from OMIM:

614212

Human phenotypes related to Encephalopathy, Acute, Infection-Induced, 4:

 63
id Description HPO Frequency HPO Source Accession
1 seizures63 HP:0001250
2 coma63 HP:0001259
3 encephalopathy63 HP:0001298
4 cerebral edema63 HP:0002181

Drugs & Therapeutics for Encephalopathy, Acute, Infection-Induced, 4

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Encephalopathy, Acute, Infection-Induced, 4


Cochrane evidence based reviews: encephalitis, viral

Genetic Tests for Encephalopathy, Acute, Infection-Induced, 4

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Anatomical Context for Encephalopathy, Acute, Infection-Induced, 4

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MalaCards organs/tissues related to Encephalopathy, Acute, Infection-Induced, 4:

35
Brain

Animal Models for Encephalopathy, Acute, Infection-Induced, 4 or affiliated genes

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Publications for Encephalopathy, Acute, Infection-Induced, 4

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Variations for Encephalopathy, Acute, Infection-Induced, 4

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Expression for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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Search GEO for disease gene expression data for Encephalopathy, Acute, Infection-Induced, 4.

Pathways for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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GO Terms for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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Cellular components related to Encephalopathy, Acute, Infection-Induced, 4 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00057399.1CPT2, RANBP2

Sources for Encephalopathy, Acute, Infection-Induced, 4

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet