MCID: ENC036
MIFTS: 28

Encephalopathy, Acute, Infection-Induced, 4 malady

Categories: Genetic diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Encephalopathy, Acute, Infection-Induced, 4

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Aliases & Descriptions for Encephalopathy, Acute, Infection-Induced, 4:

Name: Encephalopathy, Acute, Infection-Induced, 4 50 68
Encephalopathy Acute Infection-Induced 4 68 25
Encephalopathy, Acute, Infection-Induced, Susceptibility to, 4 50
Encephalopathy, Acute, Infection-Induced, 4, Susceptibility to 12
Acute Necrotizing Encephalopathy of Childhood 52
 
Isolated Acute Necrotizing Encephalopathy 52
Encephalitis, Viral 37
Isolated Ane 52
Iiae4 68
Anec 52

Characteristics:

Orphanet epidemiological data:

52
acute necrotizing encephalopathy of childhood:
Inheritance: Not applicable; Age of onset: Childhood

HPO:

62
encephalopathy, acute, infection-induced, 4:
Inheritance: autosomal dominant inheritance, autosomal recessive inheritance


Classifications:



External Ids:

OMIM50 614212
Orphanet52 ORPHA263524
ICD10 via Orphanet29 G31.8
MedGen35 C3280160
MeSH37 D018792
ICD1028 A86, A85.8

Summaries for Encephalopathy, Acute, Infection-Induced, 4

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OMIM:50 Acute encephalopathy is a severe neurologic complication of an infection that usually occurs in children. It is... (614212) more...

MalaCards based summary: Encephalopathy, Acute, Infection-Induced, 4, also known as encephalopathy acute infection-induced 4, is related to encephalitis and st. louis encephalitis, and has symptoms including seizures, coma and encephalopathy. An important gene associated with Encephalopathy, Acute, Infection-Induced, 4 is CPT2 (Carnitine Palmitoyltransferase 2). Affiliated tissues include brain.

UniProtKB/Swiss-Prot:68 Encephalopathy, acute, infection-induced, 4: A severe neurologic complication of an infection. It manifests within days in otherwise healthy children after common viral infections, without evidence of viral infection of the brain or inflammatory cell infiltration. In affected children, high-grade fever is accompanied within 12 to 48 hours by febrile convulsions, often leading to coma, multiple-organ failure, brain edema, and high morbidity and mortality. The infections are usually viral, particularly influenza, although other viruses and even mycoplasma have been found to cause the disorder.

Related Diseases for Encephalopathy, Acute, Infection-Induced, 4

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Diseases related to Encephalopathy, Acute, Infection-Induced, 4 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1encephalitis10.3
2st. louis encephalitis10.0
3herpes simplex encephalitis 110.0
4japanese encephalitis10.0
5meningitis and encephalitis9.9
6encephalopathy9.9
7viral meningitis9.8
8myelitis9.7
9venezuelan equine encephalitis9.7
10transverse myelitis9.7
11acute transverse myelitis9.7
12question mark ears, isolated9.5
13encephalopathy, acute, infection-induced, 49.5CPT2, RANBP2
14paralytic poliomyelitis9.2
15vaginitis9.2
16herpes simplex9.2
17candida glabrata9.2

Graphical network of diseases related to Encephalopathy, Acute, Infection-Induced, 4:



Diseases related to encephalopathy, acute, infection-induced, 4

Symptoms for Encephalopathy, Acute, Infection-Induced, 4

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Symptoms by clinical synopsis from OMIM:

614212

Clinical features from OMIM:

614212

HPO human phenotypes related to Encephalopathy, Acute, Infection-Induced, 4:

id Description Frequency HPO Source Accession
1 seizures HP:0001250
2 coma HP:0001259
3 encephalopathy HP:0001298
4 cerebral edema HP:0002181

Drugs & Therapeutics for Encephalopathy, Acute, Infection-Induced, 4

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Encephalopathy, Acute, Infection-Induced, 4


Cochrane evidence based reviews: encephalitis, viral

Genetic Tests for Encephalopathy, Acute, Infection-Induced, 4

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Genetic tests related to Encephalopathy, Acute, Infection-Induced, 4:

id Genetic test Affiliating Genes
1 Encephalopathy, Acute, Infection-Induced, 4, Susceptibility to25

Anatomical Context for Encephalopathy, Acute, Infection-Induced, 4

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MalaCards organs/tissues related to Encephalopathy, Acute, Infection-Induced, 4:

34
Brain

Animal Models for Encephalopathy, Acute, Infection-Induced, 4 or affiliated genes

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Publications for Encephalopathy, Acute, Infection-Induced, 4

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Variations for Encephalopathy, Acute, Infection-Induced, 4

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Expression for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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Search GEO for disease gene expression data for Encephalopathy, Acute, Infection-Induced, 4.

Pathways for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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GO Terms for genes affiliated with Encephalopathy, Acute, Infection-Induced, 4

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Cellular components related to Encephalopathy, Acute, Infection-Induced, 4 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00057399.1CPT2, RANBP2

Sources for Encephalopathy, Acute, Infection-Induced, 4

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet