Encephalopathy, Neonatal Severe malady

MalaCards: Encephalopathy, Neonatal Severe, also known as encephalopathies, is related to hepatic encephalopathy and hepatitis. An important gene associated with Encephalopathy, Neonatal Severe is MECP2 (methyl CpG binding protein 2 (Rett syndrome)).

OMIM: 300673

encephalopathy, neonatal severe 33 encephalopathies 43

Diseases related to encephalopathy, neonatal severe by text searches and GeneDecks gene sharing:

(show top 50)    (show all 185)

id	Related Disease	Score	Top Affiliating Genes
1	hepatic encephalopathy	10.3
2	hepatitis	10.2
3	ethylmalonic encephalopathy	8.9
4	glycine encephalopathy	8.7
5	mitochondrial neurogastrointestinal encephalopathy disease	8.6
6	bovine spongiform encephalopathy	8.5
7	prion disease	8.3
8	familial encephalopathy with neuroserpin inclusion bodies	8.2
9	wernicke encephalopathy	7.9
10	infantile epileptic encephalopathy	7.8
11	influenza	7.8
12	hypertensive encephalopathy	7.7
13	cerebritis	7.5
14	toxic encephalopathy	7.5
15	brain disease	7.4
16	wernicke-korsakoff syndrome	7.3
17	aicardi-goutieres syndrome	7.1
18	early myoclonic encephalopathy	7.1
19	leigh disease	7.1
20	mecp2-related severe neonatal encephalopathy	7.1
21	scrapie	7.1
22	ohtahara syndrome	7.0
23	melas syndrome	6.8
24	west syndrome	6.8
25	gerstmann-straussler-scheinker disease	6.8
26	hemorrhagic shock and encephalopathy syndrome	6.8
27	alcoholism	6.5
28	epileptic encephalopathy lennox-gastaut type	6.5
29	epileptic encephalopathy, early infantile, 4	6.5
30	microcephaly, seizures, and developmental delay	6.2
31	thyroiditis	6.2
32	biotinidase deficiency	6.2
33	creutzfeldt-jakob syndrome	6.2
34	encephalopathy (familial infantile)	6.2
35	epileptic encephalopathy, early infantile, 3	6.2
36	epileptic encephalopathy, early infantile, 1	6.2
37	immunodeficiency	6.2
38	kernicterus	6.2
39	lactic acidosis	6.2
40	liver cirrhosis	6.2
41	glucose transporter type 1 deficiency syndrome	5.9
42	kuru encephalopathy	5.9
43	cerebral beriberi	5.9
44	lethal encephalopathy due to defective mitochondrial peroxisomal fission	5.9
45	cardiomyopathy	5.9
46	myoclonic encephalopathy of infants	5.9
47	dementia	5.9
48	encephalitis	5.9
49	pontocerebellar hypoplasia type 6	5.9
50	encephalopathy intracranial calcification growth hormone deficiency microcephaly retinal degeneration	5.9

Clinical features from OMIM: 300673

Approved drugs:

Drug clinical trials:

Genes related to encephalopathy, neonatal severe according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	MECP2	methyl CpG binding protein 2 (Rett syndrome)	11.0	Disorders