Aliases & Classifications for Enchondroma

MalaCards integrated aliases for Enchondroma:

Name: Enchondroma 49 69

Classifications:



External Ids:

UMLS 69 C1704356

Summaries for Enchondroma

MalaCards based summary : Enchondroma is related to multiple enchondromatosis, maffucci type and enchondromatosis, multiple, ollier type, and has symptoms including pain An important gene associated with Enchondroma is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic), and among its related pathways/superpathways are Carbon metabolism and Glutathione metabolism. Affiliated tissues include bone, pituitary and thyroid.

Related Diseases for Enchondroma

Diseases related to Enchondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 multiple enchondromatosis, maffucci type 32.5 IDH1 IDH2
2 enchondromatosis, multiple, ollier type 32.5 IDH1 IDH2
3 chondrosarcoma 30.6 IDH1 IDH2
4 spindle cell hemangioma 29.6 IDH1 IDH2
5 periosteal chondrosarcoma 29.6 IDH1 IDH2
6 metachondromatosis 11.5
7 chondroma 11.3
8 cervicofacial fibrochondroma 10.9
9 spondyloenchondrodysplasia 10.9
10 osteochondroma 10.1
11 interval angle-closure glaucoma 10.0 IDH1 IDH2
12 adult oligodendroglioma 10.0 IDH1 IDH2
13 intracranial chondrosarcoma 10.0 IDH1 IDH2
14 glioma susceptibility 1 10.0 IDH1 IDH2
15 anaplastic oligodendroglioma 10.0 IDH1 IDH2
16 cytogenetically normal acute myeloid leukemia 10.0 IDH1 IDH2
17 chondroblastic osteosarcoma 10.0 IDH1 IDH2
18 intraductal papilloma 10.0 IDH1 IDH2
19 adult astrocytic tumour 10.0 IDH1 IDH2
20 fibrillary astrocytoma 10.0 IDH1 IDH2
21 undifferentiated pleomorphic sarcoma 10.0 IDH1 IDH2
22 drug-induced mental disorder 10.0 IDH1 IDH2
23 drug psychosis 10.0 IDH1 IDH2
24 diffuse infiltrative lymphocytosis syndrome 10.0 IDH1 IDH2
25 2-hydroxyglutaric aciduria 10.0 IDH1 IDH2
26 periostitis 9.9
27 breast papillary carcinoma 9.9 IDH1 IDH2
28 d-2-hydroxyglutaric aciduria 1 9.9 IDH1 IDH2
29 bile duct adenocarcinoma 9.9 IDH1 IDH2
30 intrahepatic cholangiocarcinoma 9.9 IDH1 IDH2
31 oligodendroglioma 9.9 IDH1 IDH2
32 episodic pain syndrome, familial, 1 9.9
33 cervicitis 9.9
34 histiocytoma 9.9
35 fibrous histiocytoma 9.9
36 aneurysm 9.9
37 brain cancer 9.8 IDH1 IDH2
38 essential thrombocythemia 9.8 IDH1 IDH2
39 glioma 9.8 IDH1 IDH2
40 myelofibrosis 9.7 IDH1 IDH2
41 breast cancer 9.7
42 camurati-engelmann disease 9.7
43 fibrodysplasia ossificans progressiva 9.7
44 fibromuscular dysplasia 9.7
45 aging 9.7
46 aneurysmal bone cysts 9.7
47 hemangioma 9.7
48 mastoiditis 9.7
49 paronychia 9.7
50 coccidioidomycosis 9.7

Graphical network of the top 20 diseases related to Enchondroma:



Diseases related to Enchondroma

Symptoms & Phenotypes for Enchondroma

UMLS symptoms related to Enchondroma:


pain

Drugs & Therapeutics for Enchondroma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Low Grade Chondrosarcoma Versus Enchondroma Completed NCT02996747

Search NIH Clinical Center for Enchondroma

Genetic Tests for Enchondroma

Anatomical Context for Enchondroma

MalaCards organs/tissues related to Enchondroma:

38
Bone, Pituitary, Thyroid, Skin

Publications for Enchondroma

Articles related to Enchondroma:

(show top 50) (show all 225)
# Title Authors Year
1
Large enchondroma of the thoracic spine: a rare case report and review of the literature. ( 28407736 )
2017
2
Diagnostic value of MRI-based 3D texture analysis for tissue characterisation and discrimination of low-grade chondrosarcoma from enchondroma: a pilot study. ( 28884356 )
2017
3
Risk factors for local recurrence from atypical cartilaginous tumour and enchondroma of the long bones. ( 28501961 )
2017
4
Another gouty tophus? The many faces of the enchondroma. ( 28242213 )
2017
5
Curettage Using Soft-wire for Enchondroma in the Hand: A Technical Note. ( 29051884 )
2017
6
Treatment of hand enchondroma with injectable calcium phosphate cement: a series of eight cases. ( 27942915 )
2017
7
Recurrence of Enchondroma in a Middle Finger after Curettage and Back-filling with Calcium Phosphate Bone Cement: a Case Report. ( 27492208 )
2016
8
Enchondroma of the Hand: Evaluation and Management. ( 27454024 )
2016
9
Predicting Fracture Risk for Enchondroma of the Hand. ( 27390564 )
2016
10
Metachondromatosis without Enchondromas: A Case Report and Review of the Literature. ( 29252664 )
2016
11
Enchondroma versus Chondrosarcoma in Long Bones of Appendicular Skeleton: Clinical and Radiological Criteria-A Follow-Up. ( 27034667 )
2016
12
Expression of insulin-like growth factor D8I mRNA binding protein 3 (IMP3) in enchondroma and chondrosarcoma. ( 26948096 )
2016
13
Use of MicroRNA biomarkers to distinguish enchondroma from low-grade chondrosarcoma. ( 27267924 )
2016
14
Enchondroma in the distal phalanx of the finger: An observational study of 34 cases in a single institution. ( 27661057 )
2016
15
Radiologic follow-up of untreated enchondroma and atypical cartilaginous tumors in the long bones. ( 27696436 )
2016
16
Primary intra-osseous myoepithelioma of phalanx mimicking an enchondroma. ( 27524490 )
2016
17
Multiple enchondromas and skin angiomas: Maffucci syndrome. ( 27037214 )
2016
18
Enchondroma Protuberans of the Ulna in a Pediatric Patient: A Case Report. ( 29252631 )
2016
19
Pathological Avulsion Fracture of the Flexor Digitorum Profundus after Enchondroma-Case Report. ( 27625544 )
2016
20
Atypical Localization of Enchondroma in the Calcaneus. ( 26146974 )
2015
21
Treatment of a fractured juxta-articular enchondroma of the middle phalanx with a Suzuki external fixator: a case report. ( 25706150 )
2015
22
Osseous tumor of the hand: finger enchondroma. ( 25671055 )
2015
23
Giant cell reparative granuloma of the hallux following enchondroma. ( 26985281 )
2015
24
The surgical management of hand enchondroma without postcurettage void augmentation: authors' experience and a systematic review. ( 26330779 )
2015
25
Avulsion of flexor digitorum profundus secondary to enchondroma of the distal phalanx. Case report and literature review. ( 26204827 )
2015
26
Atypical Localization of Enchondroma in the Calcaneus. ( 25867903 )
2015
27
Enchondroma of the cervical spine in young woman: A rare case report. ( 26425170 )
2015
28
Enchondroma of the Skull Base in a Case of Ollier's Syndrome. ( 26351491 )
2015
29
Endoscopic curettage and bone grafting of the enchondroma of the proximal phalanx of the great toe. ( 25937415 )
2015
30
Enchondroma of clivus: appearance on 18F-FDG PET-CT in contrast with MRI. ( 25489953 )
2015
31
Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma. ( 25755173 )
2015
32
Enchondroma of the Distal Phalanx. ( 26129760 )
2015
33
Nonoperative Management of Multiple Hand Enchondromas in Ollier Disease With Progressive Ossification. ( 26372762 )
2015
34
Recurrent Metacarpal Enchondroma Treated With Strut Allograft: 14-year Follow-up. ( 26186330 )
2015
35
Enchondroma of the scaphoid: a case report. ( 26327970 )
2015
36
Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma? ( 26220916 )
2015
37
Current management of hand enchondroma: a review. ( 25609298 )
2015
38
Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up. ( 25767429 )
2015
39
A Rare Occurrence of Enchondroma in Neck of Femur in an Adult Female: A Case Report. ( 26816956 )
2015
40
Enchondroma of the Foot. ( 26024560 )
2015
41
Arthroscopic treatment for femoral neck enchondroma: case report. ( 27011868 )
2015
42
A case of myelopathy because of enchondromas from Maffucci syndrome with successful surgical treatment. ( 25777744 )
2015
43
Local review of treatment of hand enchondroma (artificial bone substitute versus autologous bone graft) in a tertiary referral centre: 13 years' experience. ( 25810024 )
2015
44
Vascular pattern in enchondroma and chondrosarcoma: clinical and immunohistologic study. ( 24897071 )
2014
45
Chest wall secondary chondrosarcoma arising from enchondroma in a young Asian female. ( 25460449 )
2014
46
Hypertrophic nonunion humerus mimicking an enchondroma. ( 25525539 )
2014
47
Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up. ( 24645839 )
2014
48
Pannus tissue mimicking enchondroma. ( 24488852 )
2014
49
Chondrosarcoma arising in an enchondroma of the metacarpal bone - a case report. ( 24783111 )
2014
50
Finger enchondroma treated with bone substituents - a case presentation. ( 25408730 )
2014

Variations for Enchondroma

Expression for Enchondroma

Search GEO for disease gene expression data for Enchondroma.

Pathways for Enchondroma

GO Terms for Enchondroma

Cellular components related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.62 IDH1 IDH2

Biological processes related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.26 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.16 IDH1 IDH2
3 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
4 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 magnesium ion binding GO:0000287 9.32 IDH1 IDH2
2 NAD binding GO:0051287 9.26 IDH1 IDH2
3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
4 isocitrate dehydrogenase activity GO:0004448 8.96 IDH1 IDH2
5 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.62 IDH1 IDH2

Sources for Enchondroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
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47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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