Aliases & Classifications for Enchondroma

Aliases & Descriptions for Enchondroma:

Name: Enchondroma 50 69

Classifications:



Summaries for Enchondroma

MalaCards based summary : Enchondroma is related to enchondromatosis, multiple, ollier type and multiple enchondromatosis, maffucci type, and has symptoms including pain An important gene associated with Enchondroma is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic), and among its related pathways/superpathways are Carbon metabolism and Glutathione metabolism. Affiliated tissues include bone, bone marrow and skin.

Wikipedia : 71 An enchondroma is a cartilage cyst found in the bone marrow. Typically, enchondroma is discovered on an... more...

Related Diseases for Enchondroma

Diseases related to Enchondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
id Related Disease Score Top Affiliating Genes
1 enchondromatosis, multiple, ollier type 11.3
2 multiple enchondromatosis, maffucci type 11.2
3 chondroma 11.2
4 metachondromatosis 11.1
5 cervicofacial fibrochondroma 10.8
6 chondrosarcoma 10.4
7 optic disk drusen 10.1 IDH1 IDH2
8 acrocallosal syndrome 10.1 IDH1 IDH2
9 neurilemmoma 10.1 IDH1 IDH2
10 testis refractory cancer 10.1 IDH1 IDH2
11 cystinosis, nephropathic 10.1 IDH1 IDH2
12 small cell osteogenic sarcoma 10.1 IDH1 IDH2
13 glycogen storage disease type 0 10.0 IDH1 IDH2
14 angioma hereditary neurocutaneous 10.0 IDH1 IDH2
15 neuropathy, ataxia, and retinitis pigmentosa 10.0 IDH1 IDH2
16 breast papillomatosis 10.0 IDH1 IDH2
17 spinal cord astrocytoma 10.0 IDH1 IDH2
18 prosopagnosia 10.0 IDH1 IDH2
19 cystic lymphangioma 10.0 IDH1 IDH2
20 agammaglobulinemia 8, autosomal dominant 10.0 IDH1 IDH2
21 gummatous syphilis 10.0 IDH1 IDH2
22 amyloid tumor 10.0 IDH1 IDH2
23 t-cell adult acute lymphocytic leukemia 10.0 IDH1 IDH2
24 allergic hypersensitivity disease 10.0 IDH1 IDH2
25 vascular cancer 10.0 IDH1 IDH2
26 asynchronous multifocal osteogenic sarcoma 10.0 IDH1 IDH2
27 macrosomia with microphthalmia, lethal 10.0 IDH1 IDH2
28 osteochondroma 10.0
29 basophilic carcinoma 10.0 IDH1 IDH2
30 systemic lupus erythematosus 2 9.9 IDH1 IDH2
31 gastroesophageal junction adenocarcinoma 9.9 IDH1 IDH2
32 glucosephosphate isomerase deficiency 9.9 IDH1 IDH2
33 adult oligodendroglioma 9.9 IDH1 IDH2
34 periostitis 9.8
35 basilar artery insufficiency 9.8 IDH1 IDH2
36 histiocytoma 9.8
37 fibrous histiocytoma 9.8
38 aneurysm 9.8
39 cervicitis 9.8
40 fibrodysplasia ossificans progressiva 9.6
41 chondroblastoma 9.6
42 breast cancer 9.6
43 fibrosarcoma 9.6
44 pituitary adenoma 9.6
45 aneurysmal bone cysts 9.6
46 camurati-engelmann disease 9.6
47 spindle cell hemangioma 9.6
48 periosteal chondrosarcoma 9.6
49 adenoma 9.6
50 hemangioma 9.6

Graphical network of the top 20 diseases related to Enchondroma:



Diseases related to Enchondroma

Symptoms & Phenotypes for Enchondroma

UMLS symptoms related to Enchondroma:


pain

Drugs & Therapeutics for Enchondroma

Interventional clinical trials:


id Name Status NCT ID Phase
1 Low Grade Chondrosarcoma Versus Enchondroma Completed NCT02996747

Search NIH Clinical Center for Enchondroma

Genetic Tests for Enchondroma

Anatomical Context for Enchondroma

MalaCards organs/tissues related to Enchondroma:

39
Bone, Bone Marrow, Skin, Breast, Thyroid, Pituitary

Publications for Enchondroma

Articles related to Enchondroma:

(show top 50) (show all 218)
id Title Authors Year
1
Treatment of hand enchondroma with injectable calcium phosphate cement: a series of eight cases. ( 27942915 )
2017
2
Pathological Avulsion Fracture of the Flexor Digitorum Profundus after Enchondroma-Case Report. ( 27625544 )
2016
3
Primary intra-osseous myoepithelioma of phalanx mimicking an enchondroma. ( 27524490 )
2016
4
Multiple enchondromas and skin angiomas: Maffucci syndrome. ( 27037214 )
2016
5
Recurrence of Enchondroma in a Middle Finger after Curettage and Back-filling with Calcium Phosphate Bone Cement: a Case Report. ( 27492208 )
2016
6
Radiologic follow-up of untreated enchondroma and atypical cartilaginous tumors in the long bones. ( 27696436 )
2016
7
Enchondroma of the Hand: Evaluation and Management. ( 27454024 )
2016
8
Expression of insulin-like growth factor D8I mRNA binding protein 3 (IMP3) in enchondroma and chondrosarcoma. ( 26948096 )
2016
9
Enchondroma versus Chondrosarcoma in Long Bones of Appendicular Skeleton: Clinical and Radiological Criteria-A Follow-Up. ( 27034667 )
2016
10
Predicting Fracture Risk for Enchondroma of the Hand. ( 27390564 )
2016
11
Enchondroma in the distal phalanx of the finger: An observational study of 34 cases in a single institution. ( 27661057 )
2016
12
Use of MicroRNA biomarkers to distinguish enchondroma from low-grade chondrosarcoma. ( 27267924 )
2016
13
Enchondroma of the Distal Phalanx. ( 26129760 )
2015
14
The surgical management of hand enchondroma without postcurettage void augmentation: authors' experience and a systematic review. ( 26330779 )
2015
15
Atypical Localization of Enchondroma in the Calcaneus. ( 25867903 )
2015
16
Arthroscopic treatment for femoral neck enchondroma: case report. ( 27011868 )
2015
17
Nonoperative Management of Multiple Hand Enchondromas in Ollier Disease With Progressive Ossification. ( 26372762 )
2015
18
Enchondroma of the scaphoid: a case report. ( 26327970 )
2015
19
A Rare Occurrence of Enchondroma in Neck of Femur in an Adult Female: A Case Report. ( 26816956 )
2015
20
Enchondroma of the Skull Base in a Case of Ollier's Syndrome. ( 26351491 )
2015
21
Enchondroma of the cervical spine in young woman: A rare case report. ( 26425170 )
2015
22
Enchondroma of clivus: appearance on 18F-FDG PET-CT in contrast with MRI. ( 25489953 )
2015
23
Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up. ( 25767429 )
2015
24
Recurrent Metacarpal Enchondroma Treated With Strut Allograft: 14-year Follow-up. ( 26186330 )
2015
25
Local review of treatment of hand enchondroma (artificial bone substitute versus autologous bone graft) in a tertiary referral centre: 13 years' experience. ( 25810024 )
2015
26
Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma? ( 26220916 )
2015
27
Giant cell reparative granuloma of the hallux following enchondroma. ( 26985281 )
2015
28
Avulsion of flexor digitorum profundus secondary to enchondroma of the distal phalanx. Case report and literature review. ( 26204827 )
2015
29
Current management of hand enchondroma: a review. ( 25609298 )
2015
30
Atypical Localization of Enchondroma in the Calcaneus. ( 26146974 )
2015
31
Osseous tumor of the hand: finger enchondroma. ( 25671055 )
2015
32
Endoscopic curettage and bone grafting of the enchondroma of the proximal phalanx of the great toe. ( 25937415 )
2015
33
Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma. ( 25755173 )
2015
34
A case of myelopathy because of enchondromas from Maffucci syndrome with successful surgical treatment. ( 25777744 )
2015
35
Enchondroma of the Foot. ( 26024560 )
2015
36
Treatment of a fractured juxta-articular enchondroma of the middle phalanx with a Suzuki external fixator: a case report. ( 25706150 )
2015
37
Vascular pattern in enchondroma and chondrosarcoma: clinical and immunohistologic study. ( 24897071 )
2014
38
Regression of an enchondroma: a case report and proposed etiology. ( 25331356 )
2014
39
Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up. ( 24645839 )
2014
40
A rare cartilaginous tumor in the phalangeal bone: enchondroma protuberans. ( 24901933 )
2014
41
Pannus tissue mimicking enchondroma. ( 24488852 )
2014
42
Finger enchondroma treated with bone substituents - a case presentation. ( 25408730 )
2014
43
Enchondroma of the nasal septum due to Ollier disease: A case report and review of the literature. ( 24890303 )
2014
44
Chondrosarcoma arising in an enchondroma of the metacarpal bone - a case report. ( 24783111 )
2014
45
Hypertrophic nonunion humerus mimicking an enchondroma. ( 25525539 )
2014
46
Chest wall secondary chondrosarcoma arising from enchondroma in a young Asian female. ( 25460449 )
2014
47
MR differentiation of low-grade chondrosarcoma from enchondroma. ( 23041161 )
2013
48
Re: MR differentiation of low-grade chondrosarcoma from enchondroma. ( 23916243 )
2013
49
Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation. ( 23146901 )
2013
50
Extensive curettage using a high-speed burr versus dehydrated alcohol instillation for the treatment of enchondroma of the hand. ( 24369364 )
2013

Variations for Enchondroma

Expression for Enchondroma

Search GEO for disease gene expression data for Enchondroma.

Pathways for Enchondroma

GO Terms for Enchondroma

Cellular components related to Enchondroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.62 IDH1 IDH2

Biological processes related to Enchondroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.26 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.16 IDH1 IDH2
3 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
4 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Enchondroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 magnesium ion binding GO:0000287 9.32 IDH1 IDH2
2 NAD binding GO:0051287 9.26 IDH1 IDH2
3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
4 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH1 IDH2
5 isocitrate dehydrogenase activity GO:0004448 8.62 IDH1 IDH2

Sources for Enchondroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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