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MCID: END030
MIFTS: 55

End Stage Renal Failure malady

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for End Stage Renal Failure

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Aliases & Descriptions for End Stage Renal Failure:

Name: End Stage Renal Failure 38 12 14
End Stage Renal Disease 12 14
Chronic Kidney Disease Stage 5 69
Kidney Failure, Chronic 69

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:783
ICD10 33 N18.5
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Summaries for End Stage Renal Failure

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MalaCards based summary : End Stage Renal Failure, also known as end stage renal disease, is related to tuberculosis and pyelonephritis, and has symptoms including cloudy (hemodialysis) (peritoneal) dialysis effluent An important gene associated with End Stage Renal Failure is ALB (Albumin), and among its related pathways/superpathways are Folate Metabolism and Dilated cardiomyopathy. The drugs Capsaicin and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and bone, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 71 Chronic kidney disease (CKD), also known as chronic renal disease, is progressive loss in kidney... more...

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Related Diseases for End Stage Renal Failure

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Diseases related to End Stage Renal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 322)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 30.4 ACE IL6 TNF
2 pyelonephritis 30.0 ACE CRP TNF
3 peripheral artery disease 30.0 ACE TGFB1 TNF
4 poems syndrome 29.9 CRP EPO TF
5 goodpasture syndrome 29.5 CD79A CRP IL6 TNF
6 xanthogranulomatous pyelonephritis 28.8 ACE AGTR1 APOB CRP CST3 IL6
7 glomerulosclerosis, focal segmental, 4 11.8
8 microvascular complications of diabetes 3 11.6
9 microvascular complications of diabetes 1 11.6
10 microvascular complications of diabetes 2 11.6
11 alport syndrome 11.2
12 frasier syndrome 11.2
13 nephrotic syndrome, type 1 11.2
14 medullary cystic kidney disease 1 11.1
15 nephrotic syndrome, type 2 11.1
16 nephronophthisis-like nephropathy 1 11.1
17 glomerulopathy with fibronectin deposits 2 11.1
18 autosomal dominant medullary cystic kidney disease with hyperuricemia 11.1
19 coenzyme q10 deficiency, primary, 6 11.1
20 autosomal dominant medullary cystic kidney disease without hyperuricemia 11.1
21 nephronophthisis 11.1
22 medullary cystic kidney disease 2 11.1
23 nephrotic syndrome, type 5, with or without ocular abnormalities 10.9
24 nephronophthisis 9 10.9
25 nephrotic syndrome type 11 10.9
26 nephrotic syndrome type 12 10.9
27 nephrotic syndrome type 13 10.9
28 nephronophthisis 16 10.9
29 glomerulopathy with fibronectin deposits 1 10.9
30 nephrotic syndrome, type 3 10.9
31 hemolytic uremic syndrome, atypical 1 10.9
32 nephrotic syndrome, type 4 10.9
33 nephronophthisis 15 10.9
34 nephrotic syndrome, type 6 10.9
35 hematuria, benign familial 10.9
36 nephronophthisis 20 10.9
37 nephrocalcinosis 10.9
38 hyperuricemic nephropathy, familial juvenile 1 10.9
39 congenital dyserythropoietic anemia 10.4 ALB TNF
40 peritonitis 10.4
41 shoulder impingement syndrome 10.3 ALB CRP IL6
42 vitamin a embryopathy 10.3 EPO IL6
43 penile cancer, childhood 10.3 ACE AGT
44 cataract 10.3 ALB CRP TNF
45 atopic dermatitis 6 10.3 ALB CD79A
46 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 IL6 TNF
47 secretory diarrhea myopathy and deafness 10.3 ACE CRP IL6
48 unilateral multicystic dysplastic kidney 10.3 CRP IL6 TNF
49 hypertropia 10.3 ALB CRP TNF
50 swine influenza 10.3 CRP IL6 TNF

Graphical network of the top 20 diseases related to End Stage Renal Failure:



Diseases related to End Stage Renal Failure
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Symptoms & Phenotypes for End Stage Renal Failure

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UMLS symptoms related to End Stage Renal Failure:


cloudy (hemodialysis) (peritoneal) dialysis effluent

MGI Mouse Phenotypes related to End Stage Renal Failure:

44 (show all 14)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.46 ACE AGT AGTR1 ALB APOB CD79A
2 cardiovascular system MP:0005385 10.43 APOB COL4A5 CRP CST3 EPO IL6
3 growth/size/body region MP:0005378 10.34 ACE AGT AGTR1 APOB IL6 LEP
4 immune system MP:0005387 10.34 EPO IL6 LEP MYH9 PKD1 PTH
5 mortality/aging MP:0010768 10.3 ACE AGT AGTR1 ALB APOB COL4A5
6 hematopoietic system MP:0005397 10.29 PTH TF TGFB1 TNF ACE AGTR1
7 cellular MP:0005384 10.25 ALB APOB CD79A EPO IL6 LEP
8 adipose tissue MP:0005375 10.24 TNF UMOD ACE AGT AGTR1 COL4A5
9 liver/biliary system MP:0005370 10.14 ACE AGT ALB APOB CD79A EPO
10 muscle MP:0005369 10.02 AGT ALB APOB CST3 EPO IL6
11 neoplasm MP:0002006 9.91 ACE ALB CD79A CST3 IL6 LEP
12 nervous system MP:0003631 9.9 TNF APOB CD79A CST3 IL6 LEP
13 renal/urinary system MP:0005367 9.77 ACE AGT AGTR1 ALB CD79A COL4A5
14 reproductive system MP:0005389 9.28 ACE AGT APOB CST3 IL6 LEP
Sources

Drugs & Therapeutics for End Stage Renal Failure

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Drugs for End Stage Renal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 923)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capsaicin Approved Phase 4 404-86-4 1548943
2
Simvastatin Approved Phase 4 79902-63-9 54454
3
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Phase 2 10102-43-9 145068
4
Peginterferon alfa-2b Approved Phase 4,Phase 1 99210-65-8, 215647-85-1
5
Ribavirin Approved Phase 4,Phase 3,Phase 2,Phase 1 36791-04-5 37542
6
Digoxin Approved Phase 4 20830-75-5 30322 2724385
7
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
8
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
9
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
10
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
12
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
13
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
14
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 616-91-1 12035
15
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2 274693-27-5 9871419
16
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
17
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
18
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
19
alemtuzumab Approved, Investigational Phase 4,Phase 1,Phase 2 216503-57-0
20
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
21
Spironolactone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1952-01-7, 52-01-7 5833
22
Icodextrin Approved, Investigational Phase 4,Phase 3,Phase 2 337376-15-5
23
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
24
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
25
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
26
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
27
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
28
Alendronate Approved Phase 4 121268-17-5, 66376-36-1 2088
29
Febuxostat Approved Phase 4,Phase 2,Phase 3 144060-53-7 134018
30
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
31
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 1 54-31-9 3440
32
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Early Phase 1 58-93-5 3639
33
Ezetimibe Approved Phase 4 163222-33-1 150311
34
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
35
Baclofen Approved Phase 4 1134-47-0 2284
36
Daclizumab Approved, Investigational Phase 4,Phase 2 152923-56-3
37
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 128794-94-5 5281078
38
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 24280-93-1 446541
39
Procaine Approved, Investigational, Vet_approved Phase 4 59-46-1 4914
40
Amlodipine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 88150-42-9 2162
41
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
42
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 83-43-2 6741
43
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-24-8 5755
44
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
45
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
46
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
47
Insulin Aspart Approved Phase 4 116094-23-6 16132418
48
Zinc Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
49
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1 7439-89-6 23925
50
Losartan Approved Phase 4,Phase 3,Phase 2,Early Phase 1 114798-26-4 3961

Interventional clinical trials:

(show top 50) (show all 2216)
id Name Status NCT ID Phase
1 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4
2 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
3 Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis Unknown status NCT00291863 Phase 4
4 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
5 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4
6 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4
7 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4
8 Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal Failure Unknown status NCT00716573 Phase 4
9 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4
10 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4
11 NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED Unknown status NCT00501475 Phase 4
12 Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients Unknown status NCT00532597 Phase 4
13 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4
14 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation Unknown status NCT00807144 Phase 4
15 Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis Unknown status NCT00155363 Phase 4
16 Body Composition Monitor in Hemodialysis Patients Unknown status NCT01103167 Phase 4
17 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4
18 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4
19 Hypervolemia in ESRD Patients in Zonguldak (Prospective Study) Unknown status NCT01468363 Phase 4
20 Cardiovascular Protective Effect of Spironolactone in Hemodialysis Unknown status NCT00277693 Phase 4
21 Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR Unknown status NCT01093547 Phase 4
22 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
23 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
24 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4
25 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula Unknown status NCT00993746 Phase 4
26 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
27 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
28 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
29 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4
30 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4
31 Alendronate for Vascular Calcification in Peritoneal Dialysis Patients? Unknown status NCT00299572 Phase 4
32 The Effect of Uric Acid Lowering in Type 1 Diabetes Unknown status NCT02344602 Phase 4
33 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
34 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4
35 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4
36 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4
37 The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Unknown status NCT00247507 Phase 4
38 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4
39 Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy Unknown status NCT00861731 Phase 4
40 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4
41 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Unknown status NCT00761098 Phase 4
42 Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients Unknown status NCT02355873 Phase 4
43 Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy Unknown status NCT01386255 Phase 4
44 Fibrosis in Renal Allografts Unknown status NCT00493194 Phase 4
45 Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP Unknown status NCT00584350 Phase 4
46 Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal Unknown status NCT00896012 Phase 4
47 Quadripolar Leads for the Management of Heart Failure Patients in the Middle East Unknown status NCT02195843 Phase 4
48 Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure Completed NCT00124969 Phase 4
49 Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease Completed NCT01974817 Phase 4
50 Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5 Completed NCT02392208 Phase 4

Search NIH Clinical Center for End Stage Renal Failure

Inferred drug relations via UMLS 69 / NDF-RT 48 :
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Genetic Tests for End Stage Renal Failure

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Anatomical Context for End Stage Renal Failure

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MalaCards organs/tissues related to End Stage Renal Failure:

39
Kidney, Heart, Bone, Liver, T Cells, Pancreas, Endothelial
Sources

Publications for End Stage Renal Failure

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Articles related to End Stage Renal Failure:

(show top 50) (show all 585)
id Title Authors Year
1
Angioplasty of forearm arteries as a finger salvage procedure for patient with end-stage renal failure. ( 27143949 )
2016
2
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure. ( 27090781 )
2016
3
Fever with intradialytic pelvic pain: a case of iliopsoas abscess complicated with Methicillin-sensitive Staphylococcus Aureus bacteraemia in an end stage renal failure patient. ( 27326946 )
2016
4
Role of Procalcitonin in Differential Diagnosis of Pneumonia and Pulmonary Congestion Associated With End-Stage Renal Failure. ( 27805517 )
2016
5
Impact of HCV Infection on Diabetes Patients for the Risk of End-Stage Renal Failure. ( 26817874 )
2016
6
Unusual cause of hypercalcaemia in end stage renal failure patients. ( 27866377 )
2016
7
Defining myocardial tissue abnormalities in end-stage renal failure with cardiac magnetic resonance imaging using native T1 mapping. ( 27503805 )
2016
8
Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. ( 26942000 )
2016
9
CONTINUOUS AMBULATORY PERITONEAL DIALYSIS IN PATIENTS WITH HIV AND END-STAGE RENAL FAILURE. ( 27935535 )
2016
10
Mineral and bone disorders, morbidity and mortality in end-stage renal failure patients on chronic dialysis. ( 27004031 )
2016
11
Emergency cardiac double valve surgery in active infective endocarditis due to Acinetobacter baumannii with aortic root abscess in a patient with dialysis-dependent end-stage renal failure: a rare case report. ( 27915239 )
2016
12
Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure. ( 27279510 )
2016
13
Prevalence and Risk Factors of Lower Limb Amputation in Patients with End-Stage Renal Failure on Dialysis: A Systematic Review. ( 27529033 )
2016
14
Nocturnal blood pressure non-dipping is not associated with increased left ventricular mass index in hypertensive children without end-stage renal failure. ( 27344339 )
2016
15
Non-traumatic lower limb amputation in patients with end-stage renal failure on dialysis: an Australian perspective. ( 27277135 )
2016
16
Reversal of end-stage renal failure using direct-acting antiviral agents for chronic hepatitis C. ( 27581262 )
2016
17
The survival benefit of kidney transplantation in the setting of combined peripheral arterial disease and end-stage renal failure. ( 26914805 )
2016
18
Metastatic pulmonary calcification in end-stage renal failure. ( 27486208 )
2016
19
Crystalline cardiomyopathy due to secondary oxalosis after short-bowel syndrome and end-stage renal failure. ( 27008641 )
2016
20
Aetiology of Paediatric End-stage Renal Failure in Jordan: A Multicentre Study. ( 26684161 )
2015
21
Predictor of cardiovascular risks in end stage renal failure patients on maintenance dialysis. ( 26870086 )
2015
22
Baroreflex activation therapy in patients with end-stage renal failure: proof of concept. ( 26335429 )
2015
23
Causes of end stage renal failure among haemodialysis patients in Khartoum State/Sudan. ( 26419536 )
2015
24
Rupture of an infectious pseudoaneurysm of the aortic arch in an end-stage renal failure patient with chronic hemodialysis. ( 26042414 )
2015
25
Use of Erythropoietin-Stimulating Agents (ESA) in Patients With End-Stage Renal Failure Decided to Forego Dialysis: Palliative Perspective. ( 26718957 )
2015
26
Pharmacokinetics and pharmacodynamics of pegloticase in patients with end-stage renal failure receiving hemodialysis. ( 25816806 )
2015
27
Role of renin-angiotensin system inhibitors in retardation of progression of end-stage renal failure: a retrospective study. ( 26519376 )
2015
28
Sequential molecularly targeted drug therapy including axitinib for a patient with end-stage renal failure and metastatic renal cell carcinoma. ( 26306562 )
2015
29
Intravenous ceftaroline 200 mg administered every 8 h is safe and adequate for meticillin-resistant Staphylococcus aureus bloodstream infections in end-stage renal failure patients on haemodialysis: a case study. ( 26607339 )
2015
30
The Association between Human Leukocyte Antigens and Hypertensive End-Stage Renal Failure among Yemeni Patients. ( 26052458 )
2015
31
Calcific uraemic arteriolopathy in a patient with end-stage renal failure and chronic plaque psoriasis: could TNF-I+ inhibition help ameliorate disease progression? ( 25688703 )
2015
32
Penile lesion in end-stage renal failure - cancer or otherwise?: Calcific uremic arteriolopathy presenting with a penile lesion. ( 26085872 )
2015
33
Low Infection Rates in Total Knee Arthroplasty in End Stage Renal Failure Patients. ( 26282498 )
2015
34
Palliative care for a mentally incompetent end stage renal failure patient: why is it important? ( 25838954 )
2015
35
Epidemiology of patients in England and Wales with autosomal dominant polycystic kidney disease and end-stage renal failure. ( 24737444 )
2014
36
Evaluation of plasma concentrations of homocysteine, IL-6, TNF-alpha, hs-CRP, and total antioxidant capacity in patients with end-stage renal failure. ( 25530051 )
2014
37
Inhomogeneous Longitudinal Cardiac Rotation and Impaired Left Ventricular Longitudinal Strain in Children and Young Adults with End-Stage Renal Failure Undergoing Hemodialysis. ( 25441704 )
2014
38
Clinical Outcomes After Infrainguinal Bypass Grafting for Critical Limb Ischaemia in Patients with Dialysis-dependent End-stage Renal Failure. ( 25281532 )
2014
39
Cutaneous abnormalities in patients with end stage renal failure on chronic hemodialysis. A study of 458 patients. ( 25621088 )
2014
40
Does Off-pump Coronary Artery Bypass Confer any Advantage in Patients with End-stage Renal Failure? A Systematic Review and Meta-analysis. ( 25153358 )
2014
41
Bilateral renal cortical necrosis with end-stage renal failure following envenoming by Proatheris superciliaris: a case report. ( 24709757 )
2014
42
Bortezomib improves outcome after SCT in multiple myeloma patients with end-stage renal failure. ( 25089594 )
2014
43
Interferon alpha on NZM2328.Lc1R27: enhancing autoimmunity and immune complex-mediated glomerulonephritis without end stage renal failure. ( 24981059 )
2014
44
Gabapentin-induced myoclonus in an elderly with end-stage renal failure. ( 25103080 )
2014
45
Varicella encephalitis and pneumonia in a patient with end stage renal failure. ( 24555522 )
2014
46
Palliative care for patients with malignancy and end-stage renal failure on peritoneal dialysis. ( 25125871 )
2014
47
Functional characterization of late outgrowth endothelial progenitor cells in patients with end-stage renal failure. ( 24471420 )
2014
48
Nonattenuated Polymyxin B Used for the Treatment of Extreme-Drug Resistant Acinetobacter baumannii-Related Infections in Patients with Preexisting End Stage Renal Failure. ( 24995135 )
2014
49
Fatal End Stage Renal Failure Aggravated by Recurrent Uterine Fibroids. ( 25781304 )
2014
50
Retrospective analysis of factors predicting end-stage renal failure or death in patients with microscopic polyangiitis with mainly renal involvement. ( 24363101 )
2013
Sources

Variations for End Stage Renal Failure

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Expression for End Stage Renal Failure

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Search GEO for disease gene expression data for End Stage Renal Failure.
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Pathways for End Stage Renal Failure

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Pathways related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1
Folate Metabolism 1
Show member pathways
 12.16 ALB APOB CRP IL6 TNF
2
Dilated cardiomyopathy 37
Show member pathways
 12.11 ACE IL6 TGFB1 TNF
3
Spinal Cord Injury 1
11.9 IL6 LEP TGFB1 TNF
4
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 61
11.88 CD79A EPO IL6 TNF
5
Amoebiasis 37
11.76 COL4A5 IL6 TGFB1 TNF
6
Dendritic Cells Developmental Lineage Pathway 61
11.67 IL6 TGFB1 TNF
7
Adipogenesis 1
11.67 AGT IL6 LEP TGFB1 TNF
8
IgA-Producing B Cells in the Intestine 61
11.63 IL6 TGFB1 TNF
9
Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics 58
Show member pathways
 11.61 ACE AGT AGTR1 TGFB1
10
Jak/STAT Signaling Pathway 61
11.6 AGTR1 EPO IL6
11
HIF-1-alpha transcription factor network 1
11.58 EPO LEP TF
12
Renin secretion 37
11.57 ACE AGT AGTR1
13
Lung fibrosis 1
11.55 IL6 TGFB1 TNF
14
Primary Focal Segmental Glomerulosclerosis FSGS 1
11.49 COL4A5 MYH9 NPHS2 TGFB1
15
Malaria 37
11.42 IL6 TGFB1 TNF
16
amb2 Integrin signaling 1
11.4 APOB IL6 TNF
17
Transcription_Role of VDR in regulation of genes involved in osteoporosis 21
11.37 IL6 PTH TNF
18
AGE-RAGE signaling pathway in diabetic complications 37
11.35 AGTR1 COL4A5 IL6 TGFB1 TNF
19
Differentiation Pathway 1
11.24 EPO IL6 TF TGFB1
20
Cytokines and Inflammatory Response 1
11.15 IL6 TGFB1 TNF
21
Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers 61
11 CD79A IL6 LEP PTH TGFB1
22
Transcription factor regulation in adipogenesis 1
10.98 IL6 LEP TNF
23
Overview of nanoparticle effects 1
10.82 CRP IL6 TNF
Sources

GO Terms for End Stage Renal Failure

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Cellular components related to End Stage Renal Failure according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 ACE AGT ALB APOB CRP CST3
2 endoplasmic reticulum lumen GO:0005788 9.63 ALB APOB COL4A5 CST3 IL6 TF
3 blood microparticle GO:0072562 9.62 AGT ALB TF TGFB1
4 extracellular region GO:0005576 9.5 ACE AGT ALB APOB COL4A5 CRP
5 extracellular exosome GO:0070062 10 ACE AGT ALB APOB CRP CST3

Biological processes related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 49)
id Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.99 APOB MYH9 TGFB1 TNF
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.98 EPO IL6 TGFB1 TNF
3 aging GO:0007568 9.97 AGT EPO IL6 TGFB1
4 response to hypoxia GO:0001666 9.97 CST3 EPO LEP TGFB1
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.91 AGT IL6 TGFB1 TNF
6 regulation of cell proliferation GO:0042127 9.89 AGT AGTR1 IL6 TGFB1 TNF
7 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.87 IL6 TGFB1 TNF
8 defense response to Gram-positive bacterium GO:0050830 9.87 CRP IL6 TNF
9 regulation of blood pressure GO:0008217 9.86 ACE AGT LEP
10 kidney development GO:0001822 9.85 ACE AGT AGTR1 PKD1
11 cellular protein metabolic process GO:0044267 9.85 ALB APOB CST3 IL6 TF
12 response to estradiol GO:0032355 9.84 APOB CST3 LEP TGFB1
13 negative regulation of fat cell differentiation GO:0045599 9.82 IL6 TGFB1 TNF
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.82 AGT IL6 TNF
15 positive regulation of DNA replication GO:0045740 9.81 CST3 EPO IL6
16 acute-phase response GO:0006953 9.77 CRP EPO IL6
17 positive regulation of reactive oxygen species metabolic process GO:2000379 9.74 AGT AGTR1 LEP
18 positive regulation of cytokine production GO:0001819 9.73 AGT LEP TNF
19 positive regulation of protein kinase B signaling GO:0051897 9.73 IL6 LEP TGFB1 TNF
20 angiotensin maturation GO:0002003 9.71 ACE AGT
21 negative regulation of glucose import GO:0046325 9.7 LEP TNF
22 response to carbohydrate GO:0009743 9.7 APOB CST3
23 neutrophil mediated immunity GO:0002446 9.7 ACE IL6
24 regulation of blood vessel diameter GO:0097746 9.68 ACE AGTR1
25 positive regulation of cholesterol esterification GO:0010873 9.68 AGT AGTR1
26 response to salt stress GO:0009651 9.68 EPO TNF
27 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.67 IL6 TNF
28 positive regulation of NAD(P)H oxidase activity GO:0033864 9.65 AGT AGTR1
29 positive regulation of cell proliferation in bone marrow GO:0071864 9.65 IL6 PTH
30 regulation of vasoconstriction GO:0019229 9.65 ACE AGT AGTR1
31 renin-angiotensin regulation of aldosterone production GO:0002018 9.63 AGT AGTR1
32 regulation of renal sodium excretion GO:0035813 9.63 AGT AGTR1
33 negative regulation of extracellular matrix disassembly GO:0010716 9.62 CST3 TGFB1
34 positive regulation of mononuclear cell migration GO:0071677 9.62 TGFB1 TNF
35 metanephric ascending thin limb development GO:0072218 9.61 PKD1 UMOD
36 positive regulation of STAT protein import into nucleus GO:2000366 9.59 IL6 LEP
37 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.58 AGT AGTR1
38 positive regulation of cellular protein metabolic process GO:0032270 9.58 AGT AGTR1 TGFB1
39 response to nutrient levels GO:0031667 9.56 CST3 IL6 LEP PTH
40 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.54 AGT AGTR1 APOB
41 regulation of renal output by angiotensin GO:0002019 9.52 ACE AGT
42 mononuclear cell proliferation GO:0032943 9.51 ACE TGFB1
43 low-density lipoprotein particle remodeling GO:0034374 9.5 AGT AGTR1 APOB
44 positive regulation of superoxide anion generation GO:0032930 9.33 AGT CRP TGFB1
45 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.13 ACE AGT AGTR1
46 negative regulation of lipid storage GO:0010888 8.92 CRP IL6 LEP TNF
47 post-translational protein modification GO:0043687 10.06 ALB APOB CST3 IL6 TF
48 positive regulation of gene expression GO:0010628 10.06 APOB CRP IL6 TGFB1 TNF
49 positive regulation of cell proliferation GO:0008284 10.05 AGT CST3 EPO IL6 LEP TGFB1

Molecular functions related to End Stage Renal Failure according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.46 AGT IL6 LEP TGFB1
2 peptide hormone receptor binding GO:0051428 9.26 LEP PTH
3 hormone activity GO:0005179 9.26 AGT EPO LEP PTH
4 bradykinin receptor binding GO:0031711 8.62 ACE AGTR1
Sources

Sources for End Stage Renal Failure

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
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42 MeSH
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44 MGI
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48 NDF-RT
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55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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