MCID: END030
MIFTS: 51

End Stage Renal Failure

Categories: Nephrological diseases

Aliases & Classifications for End Stage Renal Failure

MalaCards integrated aliases for End Stage Renal Failure:

Name: End Stage Renal Failure 38 12 14
Chronic Kidney Disease Stage 5 69
End Stage Renal Disease 12
Kidney Failure, Chronic 69

Classifications:



External Ids:

Disease Ontology 12 DOID:783

Summaries for End Stage Renal Failure

MalaCards based summary : End Stage Renal Failure, also known as chronic kidney disease stage 5, is related to nephrotic syndrome, type 4 and pyelonephritis, and has symptoms including cloudy (hemodialysis) (peritoneal) dialysis effluent An important gene associated with End Stage Renal Failure is UMOD (Uromodulin), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Adipogenesis. The drugs Capsaicin and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and bone, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 72 Chronic kidney disease (CKD) is progressive loss in kidney function over a period of months or years.... more...

Related Diseases for End Stage Renal Failure

Diseases related to End Stage Renal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 340)
id Related Disease Score Top Affiliating Genes
1 nephrotic syndrome, type 4 32.6 NPHS1 NPHS2 WT1
2 pyelonephritis 30.5 ACE CRP TNF
3 polyarteritis nodosa 30.4 ALB CRP TNF
4 poems syndrome 30.3 CRP EPO TF
5 hemolytic-uremic syndrome 29.8 ALB TGFB1 TNF
6 goodpasture syndrome 29.7 CD79A CRP IL6 TNF
7 peripheral artery disease 29.6 ACE AGT ALB CRP IL6 TNF
8 cystinosis 29.6 ACE AGT ALB ANKS6 CRP UMOD
9 lymphoma 29.5 ACE ALB CD79A IL6 TNF
10 xanthogranulomatous pyelonephritis 28.6 ACE AGT ALB CRP CST3 IL6
11 glomerulosclerosis, focal segmental, 4 11.8
12 microvascular complications of diabetes 1 11.6
13 microvascular complications of diabetes 2 11.6
14 microvascular complications of diabetes 3 11.6
15 frasier syndrome 11.2
16 alport syndrome 11.2
17 glomerulopathy with fibronectin deposits 2 11.1
18 nephrotic syndrome, type 1 11.1
19 coenzyme q10 deficiency, primary, 6 11.0
20 nephronophthisis 20 11.0
21 medullary cystic kidney disease 2 11.0
22 nephronophthisis 11.0
23 autosomal dominant medullary cystic kidney disease with hyperuricemia 11.0
24 medullary cystic kidney disease 1 11.0
25 autosomal dominant medullary cystic kidney disease without hyperuricemia 11.0
26 nephrotic syndrome, type 2 11.0
27 nephronophthisis-like nephropathy 1 11.0
28 renal hypoplasia 11.0 NPHS1 NPHS2
29 renal dysplasia 10.9 NPHS1 WT1
30 hematuria, benign familial 10.9
31 nephronophthisis 15 10.9
32 nephrotic syndrome, type 6 10.9
33 nephrotic syndrome, type 11 10.9
34 nephrotic syndrome, type 5, with or without ocular abnormalities 10.9
35 mesangial proliferative glomerulonephritis 10.9
36 hyperuricemic nephropathy, familial juvenile 1 10.9
37 nephrocalcinosis 10.9
38 nephrotic syndrome, type 12 10.9
39 nephrotic syndrome 15 10.9
40 nephronophthisis 9 10.9
41 hemolytic uremic syndrome, atypical 1 10.9
42 nephrotic syndrome, type 13 10.9
43 glomerulopathy with fibronectin deposits 1 10.9
44 nephronophthisis 16 10.9
45 nephrotic syndrome, type 3 10.9
46 vitamin b12-responsive methylmalonic acidemia 10.9
47 congenital pulmonary alveolar proteinosis 10.9 NPHS1 NPHS2 WT1
48 female stress incontinence 10.9 NPHS1 NPHS2 WT1
49 hyperferritinemia-cataract syndrome 10.9 NPHS1 NPHS2 WT1
50 sarcocystosis 10.8 ALB NPHS1 NPHS2

Graphical network of the top 20 diseases related to End Stage Renal Failure:



Diseases related to End Stage Renal Failure

Symptoms & Phenotypes for End Stage Renal Failure

UMLS symptoms related to End Stage Renal Failure:


cloudy (hemodialysis) (peritoneal) dialysis effluent

MGI Mouse Phenotypes related to End Stage Renal Failure:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.38 CST3 EPO IL6 MYH9 NPHS1 NPHS2
2 cardiovascular system MP:0005385 10.35 COL4A5 CRP CST3 EPO IL6 MYH9
3 growth/size/body region MP:0005378 10.27 ACE AGT ANKS6 IL6 MYH9 NPHS2
4 hematopoietic system MP:0005397 10.21 TNF WT1 ACE CD79A COL4A5 EPO
5 immune system MP:0005387 10.21 ACE AGT CD79A COL4A5 CRP EPO
6 mortality/aging MP:0010768 10.19 WT1 ACE AGT ALB ANKS6 COL4A5
7 adipose tissue MP:0005375 10.1 PKD1 TGFB1 TNF UMOD ACE AGT
8 liver/biliary system MP:0005370 10.06 ACE AGT ALB ANKS6 CD79A EPO
9 muscle MP:0005369 9.81 TGFB1 TNF WT1 AGT ALB CST3
10 neoplasm MP:0002006 9.61 ACE ALB CD79A CST3 IL6 PKD1
11 renal/urinary system MP:0005367 9.44 ACE AGT ALB CD79A COL4A5 IL6

Drugs & Therapeutics for End Stage Renal Failure

Drugs for End Stage Renal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 736)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capsaicin Approved Phase 4 404-86-4 1548943
2
Simvastatin Approved Phase 4 79902-63-9 54454
3
Nitric Oxide Approved Phase 4,Phase 1,Phase 2 10102-43-9 145068
4
Peginterferon alfa-2b Approved Phase 4,Phase 1 99210-65-8, 215647-85-1
5
Ribavirin Approved Phase 4,Phase 3,Phase 1,Phase 2 36791-04-5 37542
6
Digoxin Approved Phase 4 20830-75-5 30322 2724385
7
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
8
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 616-91-1 12035
9
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2 274693-27-5 9871419
10
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
11
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
12
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
13
alemtuzumab Approved, Investigational Phase 4,Phase 1,Phase 2 216503-57-0
14
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
15
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 104987-11-3 445643 439492
16
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
17
Spironolactone Approved Phase 4,Phase 3,Phase 2 1952-01-7, 52-01-7 5833
18
Icodextrin Approved, Investigational Phase 4,Phase 3,Phase 2 337376-15-5
19
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
20
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
21
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
22
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
23
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
24
Alendronate Approved Phase 4 121268-17-5, 66376-36-1 2088
25
Febuxostat Approved Phase 4,Phase 2,Phase 3 144060-53-7 134018
26
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
27
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 1 54-31-9 3440
28
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3 58-93-5 3639
29
Ezetimibe Approved Phase 4 163222-33-1 150311
30
Amlodipine Approved Phase 4,Phase 3,Phase 2 88150-42-9 2162
31
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1 159351-69-6 6442177
32
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
33
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 53123-88-9 5284616 6436030 46835353
34
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
35
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 83-43-2 6741
36
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 128794-94-5 5281078
37
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 24280-93-1 446541
38
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-24-8 5755
39
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
40
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
41
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
42
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
43
Zinc Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
44
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1 7439-89-6 23925
45
Losartan Approved Phase 4,Phase 3 114798-26-4 3961
46
Calcium acetate Approved Phase 4,Phase 3 62-54-4
47
Sevelamer Approved Phase 4,Phase 3,Phase 2 52757-95-6, 152751-57-0 3085017
48
Epoprostenol Approved Phase 4,Phase 2,Phase 3 61849-14-7, 35121-78-9 5280427 5282411
49
Candesartan Approved Phase 4,Phase 3 139481-59-7 2541
50
rituximab Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 174722-31-7 10201696

Interventional clinical trials:

(show top 50) (show all 1835)

id Name Status NCT ID Phase Drugs
1 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4 QUTENZA
2 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
3 Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis Unknown status NCT00291863 Phase 4 Simvastatin
4 Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients Unknown status NCT02590081 Phase 4 Dextrose 5%;normal saline
5 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
6 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
7 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
8 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4 aspirin;Placebo
9 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4 N-acetylcysteine
10 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4 Clopidogrel first;Ticagrelor first
11 NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED Unknown status NCT00501475 Phase 4 NAC Bicarbonate
12 Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients Unknown status NCT00532597 Phase 4
13 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4 Propofol;Dexmedetomidine
14 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation Unknown status NCT00807144 Phase 4 Tacrolimus (Kidney transplant maintenance immunosuppression);Kidney transplant maintenance immunosuppression
15 Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis Unknown status NCT00155363 Phase 4
16 Body Composition Monitor in Hemodialysis Patients Unknown status NCT01103167 Phase 4
17 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4 Oxycodone
18 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4 aliskiren
19 Hypervolemia in ESRD Patients in Zonguldak (Prospective Study) Unknown status NCT01468363 Phase 4
20 Cardiovascular Protective Effect of Spironolactone in Hemodialysis Unknown status NCT00277693 Phase 4 Spironolactone (drug)
21 Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR Unknown status NCT01093547 Phase 4
22 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
23 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
24 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
25 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula Unknown status NCT00993746 Phase 4 Bupivacaine plus lidocaine;Bupivacaine 30 ml
26 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
27 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
28 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
29 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
30 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
31 Alendronate for Vascular Calcification in Peritoneal Dialysis Patients? Unknown status NCT00299572 Phase 4 alendronate (Fosamax)
32 The Effect of Uric Acid Lowering in Type 1 Diabetes Unknown status NCT02344602 Phase 4 Febuxostat
33 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
34 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4 Calcitriol;Placebo
35 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4 intravenous NAC;Placebo
36 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4 Hydrochlorothiazide and furosemide
37 The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Unknown status NCT00247507 Phase 4 acetylcysteine
38 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4 atrorvastatin 10mg;simvastatin 40mg
39 Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy Unknown status NCT00861731 Phase 4 simvastatin;EZE/simvastatin;EZE/simvastatin
40 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
41 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Unknown status NCT00761098 Phase 4 Standard Care;Experimental
42 Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients Unknown status NCT01503671 Phase 4 Atorvastatin
43 Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure Completed NCT00124969 Phase 4 Amlodipine;Placebo
44 Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease Completed NCT01974817 Phase 4
45 Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5 Completed NCT02392208 Phase 4 Telavancin
46 Parathyroidectomy in Endstage Renal Disease Completed NCT00745719 Phase 4
47 Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure Completed NCT00391287 Phase 4
48 Evaluating Aranesp® for the Treatment of Anemia in African-American Subjects With Chronic Renal Failure (CRF) Receiving Hemodialysis Completed NCT00111995 Phase 4 Aranesp®
49 Oxidative Stress and Hemodialysis Access Failure Completed NCT00410449 Phase 4 Alpha tocopherol
50 A Study in Children With Growth Failure Due to Chronic Renal Insufficiency (CRI) or End Stage Renal Disease (ESRD) Completed NCT00097617 Phase 4

Search NIH Clinical Center for End Stage Renal Failure

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for End Stage Renal Failure

Anatomical Context for End Stage Renal Failure

MalaCards organs/tissues related to End Stage Renal Failure:

39
Kidney, Heart, Bone, Endothelial, Liver, Testes, Bone Marrow

Publications for End Stage Renal Failure

Articles related to End Stage Renal Failure:

(show top 50) (show all 594)
id Title Authors Year
1
End-stage renal failure due to transthyretin amyloidosis after liver transplantation: outcomes in 19 registry cases. ( 28434351 )
2017
2
Importance of RIFLE (Risk, Injury, Failure, Loss, and End-Stage Renal Failure) and AKIN (Acute Kidney Injury Network) in Hemodialysis Initiation and Intensive Care Unit Mortality. ( 28761207 )
2017
3
Peritonitis outcomes in patients with HIV and end-stage renal failure on peritoneal dialysis: a prospective cohort study. ( 28158991 )
2017
4
Re: The Survival Benefit of Kidney Transplantation in the Setting of Combined Peripheral Arterial Disease and End-Stage Renal Failure. ( 28208552 )
2017
5
Haploidentical hematopoietic bone marrow transplantation followed by living kidney transplantation from the same donor in a sickle cell disease patient with end-stage renal failure. ( 28160086 )
2017
6
Acute thyroiditis: An under-recognized complication of parathyroidectomy in end-stage renal failure patients with secondary hyperparathyroidism. ( 28621009 )
2017
7
A pilot study of ultrasound evaluation of gastric emptying in patients with end-stage renal failure: a comparison with healthy controls. ( 28332186 )
2017
8
Atrial Fibrillation and End Stage Renal Failure in Patients Receiving Dialysis: Balancing the Risks and Benefits of Stroke Prevention. ( 28457737 )
2017
9
Role of Procalcitonin in Differential Diagnosis of Pneumonia and Pulmonary Congestion Associated With End-Stage Renal Failure. ( 27805517 )
2016
10
Nocturnal blood pressure non-dipping is not associated with increased left ventricular mass index in hypertensive children without end-stage renal failure. ( 27344339 )
2016
11
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure. ( 27090781 )
2016
12
Metastatic pulmonary calcification in end-stage renal failure. ( 27486208 )
2016
13
Impact of HCV Infection on Diabetes Patients for the Risk of End-Stage Renal Failure. ( 26817874 )
2016
14
Comparison of clinical and laboratory parameters in patients with end-stage renal failure in the outcome of chronic glomerulonephritis and patients with end-stage renal failure in the outcome of other diseases. ( 28214807 )
2016
15
Non-traumatic lower limb amputation in patients with end-stage renal failure on dialysis: an Australian perspective. ( 27277135 )
2016
16
Reversal of end-stage renal failure using direct-acting antiviral agents for chronic hepatitis C. ( 27581262 )
2016
17
Emergency cardiac double valve surgery in active infective endocarditis due to Acinetobacter baumannii with aortic root abscess in a patient with dialysis-dependent end-stage renal failure: a rare case report. ( 27915239 )
2016
18
Crystalline cardiomyopathy due to secondary oxalosis after short-bowel syndrome and end-stage renal failure. ( 27008641 )
2016
19
CONTINUOUS AMBULATORY PERITONEAL DIALYSIS IN PATIENTS WITH HIV AND END-STAGE RENAL FAILURE. ( 27935535 )
2016
20
Angioplasty of forearm arteries as a finger salvage procedure for patient with end-stage renal failure. ( 27143949 )
2016
21
The survival benefit of kidney transplantation in the setting of combined peripheral arterial disease and end-stage renal failure. ( 26914805 )
2016
22
Fever with intradialytic pelvic pain: a case of iliopsoas abscess complicated with Methicillin-sensitive Staphylococcus Aureus bacteraemia in an end stage renal failure patient. ( 27326946 )
2016
23
Defining myocardial tissue abnormalities in end-stage renal failure with cardiac magnetic resonance imaging using native T1 mapping. ( 27503805 )
2016
24
Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure. ( 27279510 )
2016
25
Unusual cause of hypercalcaemia in end stage renal failure patients. ( 27866377 )
2016
26
Mineral and bone disorders, morbidity and mortality in end-stage renal failure patients on chronic dialysis. ( 27004031 )
2016
27
Prevalence and Risk Factors of Lower Limb Amputation in Patients with End-Stage Renal Failure on Dialysis: A Systematic Review. ( 27529033 )
2016
28
Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. ( 26942000 )
2016
29
Sequential molecularly targeted drug therapy including axitinib for a patient with end-stage renal failure and metastatic renal cell carcinoma. ( 26306562 )
2015
30
Predictor of cardiovascular risks in end stage renal failure patients on maintenance dialysis. ( 26870086 )
2015
31
Role of renin-angiotensin system inhibitors in retardation of progression of end-stage renal failure: a retrospective study. ( 26519376 )
2015
32
Penile lesion in end-stage renal failure - cancer or otherwise?: Calcific uremic arteriolopathy presenting with a penile lesion. ( 26085872 )
2015
33
Low Infection Rates in Total Knee Arthroplasty in End Stage Renal Failure Patients. ( 26282498 )
2015
34
Rupture of an infectious pseudoaneurysm of the aortic arch in an end-stage renal failure patient with chronic hemodialysis. ( 26042414 )
2015
35
Intravenous ceftaroline 200 mg administered every 8 h is safe and adequate for meticillin-resistant Staphylococcus aureus bloodstream infections in end-stage renal failure patients on haemodialysis: a case study. ( 26607339 )
2015
36
Palliative care for a mentally incompetent end stage renal failure patient: why is it important? ( 25838954 )
2015
37
Aetiology of Paediatric End-stage Renal Failure in Jordan: A Multicentre Study. ( 26684161 )
2015
38
Pharmacokinetics and pharmacodynamics of pegloticase in patients with end-stage renal failure receiving hemodialysis. ( 25816806 )
2015
39
Use of Erythropoietin-Stimulating Agents (ESA) in Patients With End-Stage Renal Failure Decided to Forego Dialysis: Palliative Perspective. ( 26718957 )
2015
40
Baroreflex activation therapy in patients with end-stage renal failure: proof of concept. ( 26335429 )
2015
41
Calcific uraemic arteriolopathy in a patient with end-stage renal failure and chronic plaque psoriasis: could TNF-I+ inhibition help ameliorate disease progression? ( 25688703 )
2015
42
Causes of end stage renal failure among haemodialysis patients in Khartoum State/Sudan. ( 26419536 )
2015
43
The Association between Human Leukocyte Antigens and Hypertensive End-Stage Renal Failure among Yemeni Patients. ( 26052458 )
2015
44
Varicella encephalitis and pneumonia in a patient with end stage renal failure. ( 24555522 )
2014
45
Clinical Outcomes After Infrainguinal Bypass Grafting for Critical Limb Ischaemia in Patients with Dialysis-dependent End-stage Renal Failure. ( 25281532 )
2014
46
Palliative care for patients with malignancy and end-stage renal failure on peritoneal dialysis. ( 25125871 )
2014
47
Does Off-pump Coronary Artery Bypass Confer any Advantage in Patients with End-stage Renal Failure? A Systematic Review and Meta-analysis. ( 25153358 )
2014
48
Functional characterization of late outgrowth endothelial progenitor cells in patients with end-stage renal failure. ( 24471420 )
2014
49
Fatal End Stage Renal Failure Aggravated by Recurrent Uterine Fibroids. ( 25781304 )
2014
50
Cutaneous abnormalities in patients with end stage renal failure on chronic hemodialysis. A study of 458 patients. ( 25621088 )
2014

Variations for End Stage Renal Failure

Expression for End Stage Renal Failure

Search GEO for disease gene expression data for End Stage Renal Failure.

Pathways for End Stage Renal Failure

GO Terms for End Stage Renal Failure

Cellular components related to End Stage Renal Failure according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 ACE AGT ALB CRP CST3 EPO
2 blood microparticle GO:0072562 9.67 AGT ALB TF TGFB1
3 endoplasmic reticulum lumen GO:0005788 9.55 ALB COL4A5 CST3 IL6 TF
4 extracellular region GO:0005576 9.44 ACE AGT ALB COL4A5 CRP CST3
5 slit diaphragm GO:0036057 9.32 NPHS1 NPHS2
6 extracellular exosome GO:0070062 10 ACE AGT ALB CRP CST3 MYH9

Biological processes related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 28)
id Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.93 AGT IL6 TGFB1 TNF
2 cellular protein metabolic process GO:0044267 9.92 ALB CST3 IL6 TF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.89 EPO IL6 TGFB1 TNF
4 aging GO:0007568 9.88 AGT EPO IL6 TGFB1
5 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.81 IL6 TGFB1 TNF
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.8 AGT IL6 TGFB1 TNF
7 response to nutrient levels GO:0031667 9.77 CST3 IL6 PTH
8 negative regulation of fat cell differentiation GO:0045599 9.73 IL6 TGFB1 TNF
9 positive regulation of nitric oxide biosynthetic process GO:0045429 9.7 AGT IL6 TNF
10 positive regulation of DNA replication GO:0045740 9.69 CST3 EPO IL6
11 angiotensin maturation GO:0002003 9.64 ACE AGT
12 neutrophil mediated immunity GO:0002446 9.62 ACE IL6
13 kidney development GO:0001822 9.62 ACE AGT PKD1 WT1
14 glomerular basement membrane development GO:0032836 9.61 NPHS1 WT1
15 response to salt stress GO:0009651 9.61 EPO TNF
16 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.58 ACE AGT
17 excretion GO:0007588 9.58 NPHS1 NPHS2 UMOD
18 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.57 IL6 TNF
19 positive regulation of cell proliferation in bone marrow GO:0071864 9.55 IL6 PTH
20 acute-phase response GO:0006953 9.54 CRP EPO IL6
21 metanephric ascending thin limb development GO:0072218 9.48 PKD1 UMOD
22 negative regulation of extracellular matrix disassembly GO:0010716 9.46 CST3 TGFB1
23 positive regulation of mononuclear cell migration GO:0071677 9.43 TGFB1 TNF
24 mononuclear cell proliferation GO:0032943 9.26 ACE TGFB1
25 regulation of renal output by angiotensin GO:0002019 9.16 ACE AGT
26 positive regulation of superoxide anion generation GO:0032930 9.13 AGT CRP TGFB1
27 negative regulation of lipid storage GO:0010888 8.8 CRP IL6 TNF
28 positive regulation of transcription, DNA-templated GO:0045893 10.01 AGT EPO IL6 TGFB1 TNF WT1

Sources for End Stage Renal Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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