MCID: END016
MIFTS: 36

Endocervicitis malady

Summaries for Endocervicitis

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Endocervicitis, also known as endocervicitis unspecified, is related to adenocarcinoma and adenocarcinoma in situ. An important gene associated with Endocervicitis is MYC (v-myc avian myelocytomatosis viral oncogene homolog). The compounds estrogen and butyrate have been mentioned in the context of this disorder. Related mouse phenotypes are endocrine/exocrine gland and digestive/alimentary.

Aliases & Classifications for Endocervicitis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 40NCIt, 57SNOMED-CT
See all sources

Aliases & Descriptions:

endocervicitis 8 10 61
endocervicitis unspecified 8


External Ids:

Disease Ontology8 DOID:5757
NCIt40 C26762

Related Diseases for Endocervicitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Endocervicitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 126)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma31.3CDKN2A, CDX2, KRT5, KRT7, KRT20, MSLN
2adenocarcinoma in situ30.4CDKN2A
3neuroendocrine carcinoma30.1NKX2-1, CDX2, KRT7, KRT20, CEACAM5
4adenoma30.1CEACAM7, CEACAM5, PAX2, KRT20, KRT7, CALB2
5papillary carcinoma29.8CALB2, NKX2-1, KRT7, KRT20
6colorectal cancer29.8MYC, MUC6, MUC5AC, CDKN2A, CDX2, KRT5
7squamous cell carcinoma29.8CALB2, NKX2-1, MYC, MUC6, MUC5AC, CDKN2A
8endocervical carcinoma10.5
9mucinous adenocarcinoma10.4
10cervical intraepithelial neoplasia10.3
11trachoma10.1
12endocervical type cervical adenomyoma10.1
13endocervical type cervical mucinous adenocarcinoma10.1
14peutz-jeghers syndrome10.1
15peutz–jeghers syndrome10.1
16ovarian endometriosis10.1
17neurofibrosarcoma10.1
18ovarian mucinous adenocarcinoma10.1
19gonorrhea10.1
20infertility10.1
21endometrial mucinous adenocarcinoma10.1
22lobular neoplasia10.1
23cystadenoma10.0KRT7
24esophagitis10.0CDX2
25adenomatoid tumor10.0CALB2
26meningioma10.0CALB2
27stomach cancer10.0CDX2
28inverted papilloma10.0KRT20
29secretory meningioma10.0KRT7
30teratoma10.0KRT7, NKX2-1
31cystadenocarcinoma10.0MUC5AC, CEACAM5
32angiosarcoma10.0CALB2
33herpes simplex10.0CDX2
34bladder carcinoma10.0CDKN2A, KRT20
35malignant pleural mesothelioma10.0MSLN, CALB2
36endometriosis10.0CALB2
37bladder adenocarcinoma10.0CDX2, KRT7, KRT20
38synovial sarcoma10.0KRT7
39mucinous cystadenocarcinoma10.0CEACAM7, KRT20, KRT7
40cutaneous paget's disease10.0CEACAM7, KRT20, KRT7
41chordoma10.0KRT5, KRT7
42renal clear cell carcinoma10.0KRT7, CALB2
43thymic carcinoma10.0CALB2, NKX2-1, KRT7
44cervical squamous cell carcinoma10.0CDKN2A, CEACAM5
45biliary papillomatosis10.0MUC6
46thymus cancer10.0NKX2-1, KRT7
47signet ring cell adenocarcinoma10.0KRT7, KRT20, CEACAM5
48gastritis10.0MUC6, MUC5AC, CDX2, DEFA5, TFF2
49gallbladder cancer10.0CEACAM5, CDX2
50papilloma10.0KRT20, KRT5, CDKN2A

Graphical network of the top 20 diseases related to Endocervicitis:



Diseases related to endocervicitis

Clinical Features for Endocervicitis

Drugs & Therapeutics for Endocervicitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Endocervicitis

Drug clinical trials:

Search ClinicalTrials for Endocervicitis

Search NIH Clinical Center for Endocervicitis

Search CenterWatch for Endocervicitis

Genetic Tests for Endocervicitis

Anatomical Context for Endocervicitis

Animal Models for Endocervicitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Endocervicitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537910.2PAX2, CDX2, CDKN2A, MYC, TFF2, PDX1
2MP:00053819.8KRT5, PDX1, TFF2, NKX2-1, MYC, MUC5AC

Publications for Endocervicitis

Sources:
51PubMed
See all sources

Articles related to Endocervicitis:

(show all 23)
idTitleAuthorsYear
1
The prevalence of human papilloma virus DNA in women with mucopurulent endocervicitis. (12013119)
2002
2
Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. (10870778)
2000
3
Cytomegalovirus endocervicitis diagnosed by cervical smear. (1663024)
1991
4
Clinical predictors of Chlamydia trachomatis endocervicitis in adolescent women. Looking for the right combination. (2589276)
1989
5
Cytomegalovirus inclusion body endocervicitis: significance of CMV inclusions in endocervical biopsies. (6272103)
1981
6
Clinical response of patients with gonococcal endocervicitis and endometritis-salpingitis-peritonitis to doxycycline. (411373)
1977
7
Cul-de-sac isolates from patients with endometritis-salpingitis-peritonitis and gonococcal endocervicitis. (822716)
1976
8
Colposcopic aspects of endocervicitis. (4838313)
1974
9
New treatment of endocervicitis]. (5631984)
1967
10
Clinical viewpoint on the management of cervicitis and endocervicitis. (13758777)
1961
11
Histomorphology of cervicitis and endocervicitis. (13753272)
1961
12
Interrelationship: cervicitis-endocervicitis and cervical carcinoma. (13713695)
1961
13
Endocervicitis its role in infertility: treatment with aureomycin. (13068425)
1953
14
Oral terramycin therapy of chronic endocervicitis in infertile women. (12980154)
1952
15
Management of chronic endocervicitis in infertility. (18113709)
1949
16
A nonsurgical method of therapy for chronic endocervicitis. (20272318)
1947
17
The present status of endocervicitis. (20281182)
1947
18
Endocervicitis. (18742962)
1934
19
NONGONORRHEAL ENDOCERVICITIS AND VAGINITIS. (18741878)
1931
20
ENDOCERVICITIS-ITS ETIOLOGY, PATHOLOGY, AND TREATMENT. (18741716)
1931
21
TREATMENT OF CHRONIC ENDOCERVICITIS. (20774977)
1929
22
A CONSERVATIVE TREATMENT FOR CHRONIC ENDOCERVICITIS. (20316622)
1927
23
ELECTROTHERMOCAUTERY TREATMENT OF LEUKORRHEA DUE TO ENDOCERVICITIS. (18739169)
1923

Genetic Variations for Endocervicitis

Expression for genes affiliated with Endocervicitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Endocervicitis

Search GEO for disease gene expression data for Endocervicitis.

Pathways for genes affiliated with Endocervicitis

Compounds for genes affiliated with Endocervicitis

Sources:
45Novoseek, 24HMDB, 60Tocris Bioscience, 11DrugBank, 50PharmGKB, 29IUPHAR
See all sources

Compounds related to Endocervicitis according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1estrogen4510.7CEACAM7, CALB2
2butyrate4510.7CEACAM7, CDX2, CALB2
3tachyplesin i4510.6CDKN2A, MYC
45fluorouracil4510.5MUC6, MUC5AC, CDKN2A, CEACAM7, CEACAM5
55-aza-2deoxycytidine4510.5MYC, CDKN2A, CDX2, KRT7
6hyaluronic acid45 2411.5CALB2, MYC, KRT20, MSLN, CEACAM5
7mucicarmine4510.5CALB2, NKX2-1, KRT7, KRT20, CEACAM7, CEACAM5
8ribonucleic acid4510.5NKX2-1, MYC, MUC5AC, KRT20, CEACAM5
9thymidine45 2411.5CALB2, PDX1, MYC, CDX2, CEACAM7, CEACAM5
10neomycin4510.5PDX1, CDKN2A, CEACAM5
11threonine4510.4PDX1, NKX2-1, MYC, MUC5AC, CDKN2A, KRT5
12retinoid4510.4KRT7, KRT5, MUC5AC, MYC
13oligonucleotide4510.4PDX1, NKX2-1, MYC, MUC6, MUC5AC, CDKN2A
14b 7234510.4CEACAM5, CEACAM7, MSLN, KRT20, KRT7, NKX2-1
15hematoxylin4510.4CALB2, NKX2-1, MUC5AC, CDKN2A, KRT7, KRT20
16vegf4510.4PDX1, MYC, CDKN2A, KRT7, KRT20, MSLN
17n acetylcysteine4510.4CDKN2A, MUC5AC, MYC, PDX1
18testosterone45 60 11 2413.4CALB2, MUC5AC, CDKN2A, KRT5, KRT7, KRT20
19retinoic acid45 2411.4KLK7, PDX1, NKX2-1, MYC, MUC5AC, CDKN2A
20steroid4510.4CALB2, NKX2-1, MUC5AC, CDKN2A, CDX2, CEACAM5
21silver4510.4CALB2, CDKN2A, CEACAM5
22serine4510.3KLK7, PDX1, NKX2-1, MYC, MUC5AC, CDKN2A
23n-acetylglucosamine4510.3CEACAM5, KRT7, MUC5AC
24paraffin4510.3CALB2, NKX2-1, MYC, CEACAM5, KRT20, KRT7
25doxorubicin45 50 1112.3CEACAM5, KRT20, CDKN2A, MYC
26tyrosine4510.3CALB2, NKX2-1, MYC, MUC5AC, CDX2, KRT5
27progesterone45 60 29 11 2414.2CALB2, NKX2-1, MUC6, MUC5AC, CDKN2A, CDX2
28calcium45 50 11 2413.2KLK7, CALB2, PDX1, TFF2, MUC6, MUC5AC
29polysaccharide4510.1MUC6, MUC5AC, KRT7, CEACAM5
30cytosine45 2411.0CEACAM5, CDKN2A, PDX1

GO Terms for genes affiliated with Endocervicitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Endocervicitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1anchored to membraneGO:03122510.3CEACAM5, CEACAM7, MSLN
2Golgi lumenGO:00579610.2MUC5AC, MUC6, DEFA5
3intermediate filamentGO:00588210.0KRT20, KRT7, KRT5

Biological processes related to Endocervicitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1stem cell differentiationGO:04886310.4PAX2, PDX1
2negative regulation of transcription from RNA polymerase II promoterGO:00012210.0PAX2, CDX2, MYC, NKX2-1, PDX1

Products for genes affiliated with Endocervicitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Endocervicitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet