MCID: END039
MIFTS: 43

Endodermal Sinus Tumor

Categories: Cancer diseases, Liver diseases, Fetal diseases

Aliases & Classifications for Endodermal Sinus Tumor

MalaCards integrated aliases for Endodermal Sinus Tumor:

Name: Endodermal Sinus Tumor 12 42 14
Yolk Sac Tumor 12 52 69
Infantile Embryonal Carcinoma 12
Hepatoid Yolk Sac Tumour 12
Yolk Sac Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1911
MeSH 42 D018240
NCIt 47 C3011
SNOMED-CT 64 404081005 74409009
UMLS 69 C0014145

Summaries for Endodermal Sinus Tumor

Disease Ontology : 12 A germ cell cancer that has material basis in cells that line the yolk sac of the embryo.

MalaCards based summary : Endodermal Sinus Tumor, also known as yolk sac tumor, is related to hemolytic-uremic syndrome and mature teratoma. An important gene associated with Endodermal Sinus Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and FOXA1 transcription factor network. The drugs Bleomycin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and reproductive system

Wikipedia : 72 Endodermal sinus tumor (EST), also known as yolk sac tumor (YST), is a member of the germ cell tumor... more...

Related Diseases for Endodermal Sinus Tumor

Diseases in the Endodermal Sinus Tumor family:

Adult Endodermal Sinus Tumor

Diseases related to Endodermal Sinus Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 114)
id Related Disease Score Top Affiliating Genes
1 hemolytic-uremic syndrome 30.3 AFP ALB SERPINA1
2 mature teratoma 30.2 AFP SALL4
3 childhood endodermal sinus tumor 12.4
4 adult endodermal sinus tumor 12.3
5 ovarian endodermal sinus tumor 12.3
6 mediastinal endodermal sinus tumors 12.2
7 childhood ovarian endodermal sinus tumor 12.0
8 central nervous system endodermal sinus tumor 12.0
9 yolk sac tumor of central nervous system 11.3
10 testicular germ cell tumor 11.2
11 testicular yolk sac tumor 11.0
12 giant adenofibroma of the breast 10.7 AFP CGB3
13 clear cell variant infiltrating bladder urothelial carcinoma 10.7 AFP SERPINA1
14 polymyositis 10.7 AFP SERPINA1
15 luminal breast carcinoma 10.7 AFP ALB
16 duane retraction syndrome 10.7 AFP ALB
17 polysyndactyly with cardiac malformation 10.6 ALB SERPINA1
18 angelucci's syndrome 10.6 AFP ALB
19 idiopathic peripheral autonomic neuropathy 10.6 ALB SERPINA1
20 sphenoid sinus squamous cell carcinoma 10.6 AFP KLK3
21 mediastinum synovial sarcoma 10.6 AFP SERPINA1
22 cerebellar vermis medulloblastoma 10.6 AFP KLK3
23 uterine corpus epithelioid leiomyoma 10.6 AFP KLK3
24 vulvar sarcoma 10.6 ALB SERPINA1
25 acrofacial dysostosis 10.6 ALB SERPINA1
26 acute gonococcal cervicitis 10.6 ALB SERPINA1
27 urethral villous adenoma 10.6 AFP KLK3
28 inner ear cancer 10.6 AFP VIM
29 articulation disorder 10.6 AFP ALB
30 toxic myocarditis 10.6 ALB CGB3
31 childhood pleomorphic rhabdomyosarcoma 10.5 AFP VIM
32 mediastinum teratoma 10.5 AFP CHGA
33 capillary hemangioma 10.5 AFP ALB
34 pineal gland cancer 10.5 AFP CHGA
35 aflatoxins-related hepatocellular carcinoma 10.5 AFP VIM
36 ovarian serous cystadenocarcinoma 10.5 AFP CHGA
37 pigmented villonodular synovitis 10.5 AFP CHGA
38 signet ring cell intrahepatic cholangiocarcinoma 10.5 CHGA SERPINA1
39 aryepiglottic fold cancer 10.5 AFP ALB
40 allergic bronchopulmonary aspergillosis 10.5 ALB KLK3
41 pulmonary vein leiomyosarcoma 10.4 CHGA KLK3
42 anal fistula 10.4 AFP SERPINA1
43 mediastinal mesenchymal tumor 10.4 AFP ALPP
44 bagassosis 10.4 AFP CGB3 KLK3
45 noninfectious dermatoses of eyelid 10.4 AFP ALB SERPINA1
46 breast adenomyoepithelial adenosis 10.4 CHGA KLK3
47 pancreatic agenesis 10.4 CHGA KLK3
48 tuberculum sellae meningioma 10.4 AFP ALB SERPINA1
49 microcystic meningioma 10.4 SERPINA1 VIM
50 epilepsy with generalized tonic-clonic seizures 10.3 CGB3 CHGA

Graphical network of the top 20 diseases related to Endodermal Sinus Tumor:



Diseases related to Endodermal Sinus Tumor

Symptoms & Phenotypes for Endodermal Sinus Tumor

GenomeRNAi Phenotypes related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.72 GATA6 VIM
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.72 AFP GATA6
3 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.72 AFP
4 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.72 VIM
5 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.72 GATA6
6 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.72 VIM
7 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.72 GATA6 VIM
8 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.72 VIM
9 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.72 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-192 9.72 AFP
11 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.72 VIM AFP GATA6
12 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.72 VIM
13 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.72 GATA6
14 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.72 GATA6
15 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.72 AFP GATA6 VIM
16 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.72 GATA6
17 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.72 GATA6 VIM

MGI Mouse Phenotypes related to Endodermal Sinus Tumor:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.1 AFP CHGA GATA6 SALL4 TIMP1 VIM

Drugs & Therapeutics for Endodermal Sinus Tumor

Drugs for Endodermal Sinus Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 146)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved Phase 2, Phase 3 11056-06-7 5360373
2
Cisplatin Approved Phase 2, Phase 3, Phase 1 15663-27-1 84093 441203 2767
3
Etoposide Approved Phase 2, Phase 3, Phase 1 33419-42-0 36462
4
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
5
Paclitaxel Approved, Vet_approved Phase 2, Phase 3, Phase 1 33069-62-4 36314
6
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
7
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
8
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 5310940 9887054 43805 6857599
9
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
10
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
11
Palivizumab Approved, Investigational Phase 3 188039-54-5
12
Ribavirin Approved Phase 3 36791-04-5 37542
13
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
14
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
15
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
16
Captopril Approved Phase 3 62571-86-2 44093
17
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
18
Fluconazole Approved Phase 3 86386-73-4 3365
19
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
20
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
21
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
22
Ondansetron Approved Phase 3 99614-02-5 4595
23
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
24
Promethazine Approved Phase 3 60-87-7 4927
25
Vinblastine Approved Phase 3 865-21-4 13342 241903
26 Albumin-Bound Paclitaxel Phase 2, Phase 3, Phase 1
27 Anti-Bacterial Agents Phase 2, Phase 3, Phase 1
28 Antibiotics, Antitubercular Phase 2, Phase 3
29 Antimitotic Agents Phase 2, Phase 3, Phase 1
30 Antineoplastic Agents, Phytogenic Phase 2, Phase 3, Phase 1
31 Etoposide phosphate Phase 2, Phase 3, Phase 1
32 Topoisomerase Inhibitors Phase 2, Phase 3, Phase 1
33 Alkylating Agents Phase 3,Phase 1,Phase 2
34 Isophosphamide mustard Phase 3,Phase 1,Phase 2
35 Anti-Infective Agents Phase 3,Phase 1,Phase 2
36 Antimetabolites Phase 3,Phase 1,Phase 2
37 Antiviral Agents Phase 3,Phase 1,Phase 2
38 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
39 BB 1101 Phase 3,Phase 1,Phase 2
40 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
41 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
42 Antibodies Phase 3,Phase 1
43 Antibodies, Monoclonal Phase 3,Phase 1
44 Immunoglobulins Phase 3,Phase 1
45 Antifungal Agents Phase 3
46 Antiparasitic Agents Phase 3
47 Antiprotozoal Agents Phase 3
48 Echinocandins Phase 3
49 Liposomal amphotericin B Phase 3
50 Angiotensin-Converting Enzyme Inhibitors Phase 3

Interventional clinical trials:

(show top 50) (show all 58)

id Name Status NCT ID Phase Drugs
1 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
4 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
5 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
7 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
9 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
10 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
11 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
12 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
13 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
14 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3 cisplatin;etoposide
15 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
16 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
17 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
18 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
19 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
20 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
21 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
22 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
23 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
24 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
25 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
26 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
27 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
28 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
29 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
30 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
31 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
32 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
33 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
34 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
35 MEN-10755 in Treating Patients With Solid Tumors Completed NCT00003982 Phase 1 sabarubicin
36 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
37 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
38 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
39 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
40 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
41 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
42 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
43 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1 lapatinib;paclitaxel
44 Biological Therapy in Treating Patients With Metastatic Cancer Completed NCT00004604 Phase 1
45 Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma Completed NCT01273090 Phase 1 imetelstat sodium
46 PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
47 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors Completed NCT00003141 Phase 1 carboplatin;cisplatin;cyclophosphamide;etoposide;thiotepa;vincristine sulfate
48 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
49 Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors Terminated NCT00238173 Phase 1 acetylcysteine;carboplatin;cyclophosphamide;etoposide phosphate;mannitol;sodium thiosulfate
50 Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Completed NCT00060021

Search NIH Clinical Center for Endodermal Sinus Tumor

Cochrane evidence based reviews: endodermal sinus tumor

Genetic Tests for Endodermal Sinus Tumor

Anatomical Context for Endodermal Sinus Tumor

MalaCards organs/tissues related to Endodermal Sinus Tumor:

39
Ovary, Bone, Brain, Bone Marrow, Spinal Cord, Pineal, Liver

Publications for Endodermal Sinus Tumor

Articles related to Endodermal Sinus Tumor:

(show top 50) (show all 255)
id Title Authors Year
1
Brief Report: A Second Primary Endodermal Sinus Tumor 9A Years after Initial Diagnosis. ( 27818263 )
2016
2
Germ Cell Tumor Targeting Chemotherapy in Gastric Adenocarcinoma with an Endodermal Sinus Tumor Component: A Case Report. ( 27351795 )
2016
3
Retroperitoneal Endodermal Sinus Tumor Patient with Palliative Care Needs. ( 26962288 )
2016
4
Sinonasal yolk sac (Endodermal sinus) tumor in an adult female--A case report and review of the literature. ( 26095665 )
2015
5
Primary cerebellar endodermal sinus tumor: A case report. ( 25202397 )
2014
6
Treatment of ovarian endodermal sinus tumor to preserve fertility. ( 23351423 )
2013
7
Primary endodermal sinus tumor in the posterior cranial fossa: clinical analysis of 7 cases. ( 24382224 )
2013
8
Endodermal sinus tumor of vagina in infants. ( 23888222 )
2013
9
Endodermal sinus tumor of vagina posing a diagnostic challenge and managed by chemotherapy and novel posterior sagittal surgical approach: Lessons learned. ( 24118204 )
2013
10
Metrorrhagia in a child with an endodermal sinus tumor of the vagina A case report. ( 23103591 )
2012
11
Endodermal sinus tumor of testis with acute intestinal obstruction: A rare presentation. ( 22279365 )
2012
12
Endodermal sinus tumor of the vagina in a child. ( 24293886 )
2012
13
Endodermal sinus tumor of the ovary in an 86A year old woman. ( 24371620 )
2012
14
Endodermal Sinus Tumor Presented With Ascites: A Case Report. ( 27785191 )
2012
15
The clinical features and treatment of endodermal sinus tumor of vagina. ( 22819272 )
2012
16
Conservative treatment and long-term follow up of endodermal sinus tumor of the vagina. ( 22178761 )
2012
17
Primary vulvar endodermal sinus tumor: a case report and review of the literature. ( 21696509 )
2011
18
Management of recurrent endodermal sinus tumor of the ovary associated with pregnancy. ( 21600636 )
2011
19
Type 2 sacrococcygeal teratoma endodermal sinus tumor. ( 22124518 )
2011
20
Mediastinal endodermal sinus tumor associated with fatal hemophagocytic syndrome. ( 21982889 )
2011
21
Retroperitoneal extragonadal endodermal sinus tumor with bilateral diffuse classic testicular microlithiasis. ( 21098858 )
2010
22
Ruptured ovarian endodermal sinus tumor diagnosed during pregnancy: case report and review of the literature. ( 21058449 )
2010
23
Endodermal sinus tumor: a rare cause of calcified peritoneal implants. ( 19602468 )
2009
24
Endodermal sinus tumor of the vagina in children: a report of two cases. ( 19679975 )
2009
25
A case of ovarian endodermal sinus tumor diagnosed during pregnancy. ( 18672645 )
2008
26
Endodermal sinus tumor of the paranasal sinuses. ( 17902152 )
2008
27
Outcome and reproductive function after cumulative high-dose combination chemotherapy with bleomycin, etoposide and cisplatin (BEP) for patients with ovarian endodermal sinus tumor. ( 18656249 )
2008
28
Primary orbital endodermal sinus tumor (yolk sac tumor). ( 18835732 )
2008
29
Adjuvant chemotherapy in a pregnant woman with endodermal sinus tumor of the ovary. ( 17267887 )
2007
30
Endodermal sinus tumor of the vagina. ( 16200632 )
2007
31
Epidural metastases from endodermal sinus tumor arising from benign sacral teratoma. Case report and review of the literature. ( 17941495 )
2007
32
Isolated orbital endodermal sinus tumor. ( 18030121 )
2007
33
Ultrasound and magnetic resonance images of endodermal sinus tumor. ( 18063508 )
2007
34
Primary endodermal sinus tumor of the vulva in a 52-year-old woman with long-term survival: a case report. ( 18179148 )
2007
35
Endodermal sinus tumor diagnosed in pregnancy: a case report. ( 17635618 )
2007
36
Gastric adenocarcinoma with features of endodermal sinus tumor. ( 17729401 )
2007
37
A case of endodermal sinus tumor associated with the first pregnancy and successful management of the second pregnancy: a case report and review of the literature. ( 17479685 )
2007
38
Primary endodermal sinus tumor of the cerebellar hemisphere: a case report with review of the literature. ( 16314958 )
2006
39
Endodermal sinus tumor of the infant vagina treated exclusively with chemotherapy. ( 17114968 )
2006
40
Integrated 18F-fluorodeoxyglucose positron emission tomography and computerized tomography in endodermal sinus tumor. ( 16884385 )
2006
41
Successful treatment of an endodermal sinus tumor of the vagina by chemotherapy alone: a rare case of an infant diagnosed by pathological examination of discharged tumor fragment. ( 16928651 )
2006
42
Primary yolk sac tumor (endodermal sinus tumor) of the vulva: case report and review of the literature. ( 17009634 )
2006
43
Disseminated peritoneal tuberculosis mimicking advanced-stage endodermal sinus tumor: a case report. ( 16515609 )
2006
44
Endodermal sinus tumor of the ovary: the Hacettepe University experience. ( 16026921 )
2005
45
Endodermal sinus tumor of the omentum: case report. ( 16457159 )
2005
46
Vaginal endodermal sinus tumor. ( 16186686 )
2005
47
Endodermal sinus tumor of the parotid gland in a child. ( 15255038 )
2004
48
Hemolytic uremic syndrome presenting after treatment of endodermal sinus tumor. ( 15516446 )
2004
49
Endodermal sinus tumor of the vulva: successfully treated with high-dose chemotherapy. ( 15361214 )
2004
50
Primary prostatic endodermal sinus tumor (yolk sac tumor) combined with a small focal seminoma. ( 12657943 )
2003

Variations for Endodermal Sinus Tumor

Expression for Endodermal Sinus Tumor

Search GEO for disease gene expression data for Endodermal Sinus Tumor.

Pathways for Endodermal Sinus Tumor

Pathways related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.15 AFP ALB ALPP SERPINA1 VIM
2
Show member pathways
10.82 KLK3 SERPINA1
3 10.6 AFP ALB

GO Terms for Endodermal Sinus Tumor

Cellular components related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.73 AFP ALB CHGA KLK3 SERPINA1 TIMP1
2 extracellular region GO:0005576 9.7 AFP ALB CGB3 CHGA KLK3 SERPINA1
3 endoplasmic reticulum lumen GO:0005788 9.26 AFP ALB SERPINA1 TIMP1
4 platelet alpha granule lumen GO:0031093 8.8 ALB SERPINA1 TIMP1

Biological processes related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.33 ALB SERPINA1 TIMP1
2 post-translational protein modification GO:0043687 9.26 AFP ALB SERPINA1 TIMP1
3 cellular protein metabolic process GO:0044267 9.1 AFP ALB GATA6 KLK3 SERPINA1 TIMP1

Sources for Endodermal Sinus Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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