MCID: END051
MIFTS: 24

Endolymphatic Sac Tumor malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Endolymphatic Sac Tumor

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Aliases & Descriptions for Endolymphatic Sac Tumor:

Name: Endolymphatic Sac Tumor 45 65
 
Elst 45


Classifications:



Summaries for Endolymphatic Sac Tumor

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Wikipedia:68 An endolymphatic sac tumor is a very uncommon papillary epithelial neoplasm arising within the... more...

MalaCards based summary: Endolymphatic Sac Tumor, also known as elst, is related to kidney disease and von hippel-lindau syndrome. An important gene associated with Endolymphatic Sac Tumor is KRT8 (Keratin 8, Type II), and among its related pathways are EGFR1 Signaling Pathway and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include bone, and related mouse phenotype renal/urinary system.

Related Diseases for Endolymphatic Sac Tumor

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Graphical network of the top 20 diseases related to Endolymphatic Sac Tumor:



Diseases related to endolymphatic sac tumor

Symptoms for Endolymphatic Sac Tumor

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Drugs & Therapeutics for Endolymphatic Sac Tumor

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac TumorsCompletedNCT00001668
2Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) PatientsRecruitingNCT02420067

Search NIH Clinical Center for Endolymphatic Sac Tumor

Genetic Tests for Endolymphatic Sac Tumor

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Anatomical Context for Endolymphatic Sac Tumor

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MalaCards organs/tissues related to Endolymphatic Sac Tumor:

33
Bone

Animal Models for Endolymphatic Sac Tumor or affiliated genes

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MGI Mouse Phenotypes related to Endolymphatic Sac Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.5AVPR2, KRT7, VHL

Publications for Endolymphatic Sac Tumor

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Articles related to Endolymphatic Sac Tumor:

(show top 50)    (show all 75)
idTitleAuthorsYear
1
Characterization of endolymphatic sac tumors and von Hippel-Lindau disease in the international ELST registry. (25867206)
2015
2
An endolymphatic sac tumor with imaging features of aneurysmal bone cysts: differential diagnostic considerations. (24881035)
2014
3
Sporadic endolymphatic sac tumor--a diagnostic and therapeutic challenge. (24966979)
2014
4
Endolymphatic sac tumor with von Hippel-Lindau disease: report of a case with atypical pathology of endolymphatic sac tumor. (24966975)
2014
5
Cerebrospinal fluid cytology of an endolymphatic sac tumor. (25354959)
2014
6
Surgical resection of endolymphatic sac tumors in von Hippel-Lindau disease: findings, results, and indications. (23070752)
2013
7
Papillary endolymphatic sac tumor: Catastrophic presentation in a child. (24060358)
2013
8
von Hippel-Lindau disease: deafness due to a non-MRI-visible endolymphatic sac tumor despite targeted screening. (24003980)
2013
9
Surgical treatment of endolymphatic sac tumor. (22201305)
2012
10
Diagnostic value of EAAT-1 and Kir7.1 for distinguishing endolymphatic sac tumors from choroid plexus tumors. (22706862)
2012
11
Papillary endolymphatic sac tumor: a case report. (22953101)
2012
12
Endolymphatic sac tumor and angiomatous lesions of the nasal and pharyngeal mucosa as a first manifestation of von Hippel-Lindau disease. (22777797)
2012
13
Conservative management of endolymphatic sac tumors in von Hippel-Lindau disease: case report. (21103895)
2011
14
Gamma knife treatment of an endolymphatic sac tumor: unique features of a case and review of the literature. (21891944)
2011
15
Flap reconstruction and hyperbaric oxygen therapy in the management of temporal bone osteoradionecrosis in an endolymphatic sac tumor: case report. (23984214)
2011
16
Endolymphatic sac tumor with overexpression of V2 receptor mRNA and inner ear hydrops. (21574774)
2011
17
Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): sine qua non radiology-pathology and the University of Texas MD Anderson Cancer Center experience. (21167761)
2011
18
Endolymphatic sac tumor presenting with MAcniA"re's disease. (20493370)
2010
19
Endolymphatic sac tumors in von Hippel-Lindau disease: report of three cases. (20351605)
2010
20
Endolymphatic sac tumor of cerebellopontine angle. (19670571)
2009
21
Endolymphatic sac tumor and von Hippel-Lindau disease in a single family. (20069227)
2009
22
Giant intracranial endolymphatic sac tumor (ELST). Case presentation and histogenetic considerations. (18273509)
2008
23
Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene. (18423895)
2008
24
Surgery for endolymphatic sac tumor: whether and when to keep hearing? (19086306)
2008
25
Endolymphatic sac tumor: a report of 3 cases and discussion of management. (17315832)
2007
26
Cochlear implantation in a bilateral endolymphatic sac tumor patient. A case report. (17825433)
2007
27
Endolymphatic sac tumor of temporal bone. (16883752)
2006
28
Endolymphatic sac tumor located around semicircular canals. (16466878)
2006
29
Endolymphatic sac tumor metastatic to the spine. Case report. (16122027)
2005
30
Coexpression of erythropoietin and its receptor in endolymphatic sac tumors. (16175858)
2005
31
Differential grading of endolymphatic sac tumor extension by virtue of von Hippel-Lindau disease status. (15354010)
2004
32
Endolymphatic sac tumors in von Hippel-Lindau disease. (15035284)
2004
33
Endolymphatic sac tumor in a 4-year-old boy. (15354011)
2004
34
Endolymphatic sac tumor in von Hippel-Lindau disease. (14501465)
2003
35
Pathologic quiz case: a woman with right facial nerve paralysis. Endolymphatic sac tumor associated with von Hippel-Lindau disease. (14521446)
2003
36
Endolymphatic sac tumor: staged endovascular-neurosurgical approach. (12739230)
2003
37
Endolymphatic sac tumor (low-grade papillary adenocarcinoma) of the temporal bone. (14710902)
2003
38
Endolymphatic sac tumor: unique features of two cases and review of the literature. (12382133)
2002
39
Cytology of endolymphatic sac tumor. (11557790)
2001
40
Endolymphatic sac tumor: a case report. (11489369)
2001
41
Endolymphatic sac tumor associated with a von Hippel-Lindau disease patient: an immunohistochemical study. (11455007)
2001
42
Mutation of von Hippel-Lindau tumor suppressor gene in a sporadic endolymphatic sac tumor. (11727270)
2001
43
VHL gene inactivation in an endolymphatic sac tumor associated with von Hippel-Lindau disease. (10932304)
2000
44
Central nervous system hemangioblastomas, endolymphatic sac tumors, and von Hippel-Lindau disease. (10809480)
2000
45
Endolymphatic sac tumor and von Hippel-Lindau disease: imaging features. (10954517)
2000
46
VHL gene inactivation in an endolymphatic sac tumor associated with von Hippel-Lindau disease. (10408561)
1999
47
Image interpretation session: 1998. Papillary endolymphatic sac tumor. (10722365)
1999
48
A case of endolymphatic sac tumor with long-term survival. (10746963)
1999
49
von Hippel-Lindau disease gene alterations associated with endolymphatic sac tumor. (9214679)
1997
50
Endolymphatic sac tumor: a case report and review of the literature. (9315135)
1997

Variations for Endolymphatic Sac Tumor

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Expression for genes affiliated with Endolymphatic Sac Tumor

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Search GEO for disease gene expression data for Endolymphatic Sac Tumor.

Pathways for genes affiliated with Endolymphatic Sac Tumor

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Pathways related to Endolymphatic Sac Tumor according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4KRT7, KRT8
2
Show member pathways
9.4KRT7, KRT8

GO Terms for genes affiliated with Endolymphatic Sac Tumor

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Cellular components related to Endolymphatic Sac Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.5KRT7, KRT8
2keratin filamentGO:00450959.4KRT7, KRT8
3intermediate filament cytoskeletonGO:00451119.3KRT8, VHL

Molecular functions related to Endolymphatic Sac Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.4KRT7, KRT8

Sources for Endolymphatic Sac Tumor

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet