ESS
MCID: END031
MIFTS: 50

Endometrial Stromal Sarcoma (ESS) malady

Categories: Rare diseases, Reproductive diseases, Cancer diseases

Aliases & Classifications for Endometrial Stromal Sarcoma

Aliases & Descriptions for Endometrial Stromal Sarcoma:

Name: Endometrial Stromal Sarcoma 12 50 56 14 69
Ess 12 50
Endometrial Stromal Sarcoma, High Grade 12
Undifferentiated Endometrial Sarcoma 12
Stromal Sarcoma of the Corpus Uteri 56
Undifferentiated Stromal Sarcoma 69
Sarcoma, Endometrial Stromal 42
Sarcoma Endometrial Stromal 52

Classifications:



External Ids:

Disease Ontology 12 DOID:4226
MeSH 42 D018203
NCIt 47 C8973
SNOMED-CT 64 699356008 70555003
Orphanet 56 ORPHA213711
MESH via Orphanet 43 D018203
UMLS via Orphanet 70 C0206630
ICD10 via Orphanet 34 C54.1
UMLS 69 C0206630

Summaries for Endometrial Stromal Sarcoma

NIH Rare Diseases : 50 endometrial stromal sarcoma is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the uterus. endometrial stromal sarcoma, specifically, develops in the supporting connective tissue (stroma) of the uterus. signs and symptoms of the condition include abnormal uterine bleeding (i.e. bleeding that is not part of menstrual periods or bleeding after menopause); abdominal pain and/or distension; and frequent urination. the exact underlying cause of endometrial stromal sarcoma is currently unknown. most cases occur sporadically in people with no family history of the condition. treatment varies based on the severity of the condition but may include surgery, radiation therapy, chemotherapy, and/or hormone therapy. last updated: 2/15/2016

MalaCards based summary : Endometrial Stromal Sarcoma, also known as ess, is related to myoma and intestinal obstruction. An important gene associated with Endometrial Stromal Sarcoma is SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit), and among its related pathways/superpathways are Integrated Breast Cancer Pathway and Striated Muscle Contraction. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include uterus, smooth muscle and lung, and related phenotypes are cardiovascular system and cellular

Wikipedia : 71 Endometrial stromal sarcoma is a malignant subtype of endometrial stromal tumor arising from the stroma... more...

Related Diseases for Endometrial Stromal Sarcoma

Diseases related to Endometrial Stromal Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
id Related Disease Score Top Affiliating Genes
1 myoma 30.5 ACTC1 DES VIM
2 intestinal obstruction 30.2 ACTC1 DES VIM
3 uterine corpus endometrial stromal sarcoma 12.1
4 cervical endometrial stromal sarcoma 12.1
5 vaginal endometrial stromal sarcoma 12.1
6 empty sella syndrome 11.5
7 endometrial stromal nodule 11.4
8 sarcoma 11.1
9 euthyroid sick syndrome 10.8
10 endometriosis 10.5
11 bartholin's gland benign neoplasm 10.4 ESR1 PGR
12 lymphomatous thyroiditis 10.4 DES PGR VIM
13 lymphomatoid papulosis 10.4 ACTC1 VIM
14 her2-receptor negative breast cancer 10.4 CYP19A1 ESR1 PGR
15 adult endodermal sinus tumor 10.4 DES PGR VIM
16 osteogenesis imperfecta 10.4 CYP19A1 ESR1 PGR
17 inflammatory linear verrucous epidermal nevus 10.4 DES VIM
18 small intestinal vasoactive intestinal peptide producing tumor 10.4 DES ESR1 MME
19 oral erosive lichen 10.4 ACTC1 DES
20 acute thyroiditis 10.4 CYP19A1 ESR1 PGR
21 cardiovascular organ benign neoplasm 10.4 ESR1 PGR
22 bladder adenocarcinoma 10.4 ESR1 PGR VIM
23 osteomyelitis 10.4 ACTC1 DES VIM
24 congenital myasthenic syndrome 10.4 ACTC1 DES VIM
25 perinatal jaundice due to hepatocellular damage 10.4 CYP19A1 ESR1 PGR
26 spleen angiosarcoma 10.4 ACTC1 DES VIM
27 malignant dermis tumor 10.4 ACTC1 DES VIM
28 urethral cancer 10.4 ACTC1 DES VIM
29 deafness, autosomal recessive 74 10.4 CYP19A1 ESR1 PGR
30 bronchus adenoma 10.4 ESR1 PGR
31 chest wall parachordoma 10.4 ACTC1 VIM
32 glioma 10.4 ESR1 PGR
33 vulvar squamous papilloma 10.4 DES ESR1 VIM
34 atypical lipomatous tumor 10.4 ESR1 KIT PGR
35 carbon monoxide-induced parkinsonism 10.4 ACTC1 DES KIT
36 male urethral cancer 10.4 ACTC1 DES VIM
37 esophagus sarcoma 10.4 CYP19A1 ESR1 PGR
38 jewett-marshall bladder cancer 10.4 DES PGR VIM
39 aortitis 10.4 PGR TP53
40 mediastinum liposarcoma 10.4 ACTC1 DES VIM
41 dyslexia 10.4 ACTC1 DES VIM
42 vulva basal cell carcinoma 10.4 ESR1 KIT PGR
43 middle ear adenocarcinoma 10.4 ESR1 KIT PGR
44 t-cell adult acute lymphocytic leukemia 10.4 ESR1 MME PGR
45 capillary disease 10.4 CYP19A1 ESR1 PGR
46 lung clear cell carcinoma 10.4 ESR1 MME PGR
47 appendix leiomyoma 10.4 ESR1 MB PGR
48 haverhill fever 10.4 CYP19A1 ESR1 PGR
49 omodysplasia 2 10.4 ACTC1 DES VIM
50 pericardium leiomyoma 10.4 ACTC1 PGR TP53

Graphical network of the top 20 diseases related to Endometrial Stromal Sarcoma:



Diseases related to Endometrial Stromal Sarcoma

Symptoms & Phenotypes for Endometrial Stromal Sarcoma

MGI Mouse Phenotypes related to Endometrial Stromal Sarcoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.25 INHA KIT MB PGR TP53 VIM
2 cellular MP:0005384 10.18 ACTC1 CCND1 CYP19A1 DES ESR1 KIT
3 homeostasis/metabolism MP:0005376 10.13 ACTC1 CCND1 CYP19A1 DES ESR1 INHA
4 mortality/aging MP:0010768 10.07 ACTC1 BCOR CCND1 DES ESR1 INHA
5 embryo MP:0005380 9.97 KIT MB PGR SUZ12 TP53 VIM
6 muscle MP:0005369 9.85 ACTC1 CYP19A1 DES ESR1 KIT MB
7 neoplasm MP:0002006 9.5 CCND1 ESR1 INHA KIT PGR SUZ12
8 reproductive system MP:0005389 9.28 CCND1 CYP19A1 ESR1 INHA KIT PGR

Drugs & Therapeutics for Endometrial Stromal Sarcoma

Drugs for Endometrial Stromal Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 117)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
2
Ifosfamide Approved Phase 3 3778-73-2 3690
3
Lenograstim Approved Phase 3 135968-09-1
4
Mechlorethamine Approved Phase 3 51-75-2 4033
5
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
6
Cyproheptadine Approved Phase 3 129-03-3 2913
7
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
8
Dehydroepiandrosterone Approved, Nutraceutical Phase 3 53-43-0 9860744
9
Doxil Approved June 1999 Phase 3,Phase 2 31703
10 Alkylating Agents Phase 3,Phase 2
11 Antineoplastic Agents, Alkylating Phase 3,Phase 2
12 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
13 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
14 Isophosphamide mustard Phase 3
15 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
16 Adjuvants, Anesthesia Phase 3
17 Analgesics Phase 3
18 Analgesics, Opioid Phase 3
19 Anesthetics Phase 3
20 Anesthetics, General Phase 3
21 Anesthetics, Intravenous Phase 3
22 Central Nervous System Depressants Phase 3
23 Liver Extracts Phase 3,Phase 1
24 Narcotics Phase 3
25 pancreatic polypeptide Phase 3
26 Peripheral Nervous System Agents Phase 3,Phase 2
27 Gastrointestinal Agents Phase 3,Phase 2
28 Adjuvants, Immunologic Phase 3
29 Anti-Allergic Agents Phase 3
30 Antipruritics Phase 3
31 Dermatologic Agents Phase 3
32 Histamine Antagonists Phase 3
33 Histamine H1 Antagonists Phase 3
34
Histamine Phosphate Phase 3 51-74-1 65513
35 Neurotransmitter Agents Phase 3
36
Serotonin Phase 3 50-67-9 5202
37 Serotonin Agents Phase 3
38 Serotonin Antagonists Phase 3
39 Cola Nutraceutical Phase 3,Phase 1
40 DHEA (Dehydroepiandrosterone) Nutraceutical Phase 3
41
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
42
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
43
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
44
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754 657311
45
Mifepristone Approved, Investigational Phase 2 84371-65-3 55245
46
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
47
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
48
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
49
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
50
Metformin Approved Phase 2 657-24-9 14219 4091

Interventional clinical trials:

(show all 47)
id Name Status NCT ID Phase
1 Radiation Therapy or No Further Treatment Following Surgery in Treating Patients With Cancer of the Uterus Completed NCT00002459 Phase 3
2 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3
3 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3
4 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
5 Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms Active, not recruiting NCT01376349 Phase 3
6 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3
7 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2
8 Nutritional Supplements in Improving Quality of Life During First-Line Chemotherapy in Patients With Metastatic Gynecological Cancer Unknown status NCT00905658 Phase 2
9 Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492 Completed NCT02150213 Phase 2
10 Mifepristone for Patients With Endometrial Cancer and LGESS Completed NCT00505739 Phase 2
11 Chemotherapy in Treating Patients With Sarcoma of the Uterus Completed NCT00005643 Phase 2
12 AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00659360 Phase 2
13 Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract Completed NCT00003334 Phase 2
14 Thalidomide in Treating Patients With Gynecologic Sarcomas Completed NCT00006005 Phase 2
15 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2
16 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2
17 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2
18 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2
19 Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer Completed NCT01210222 Phase 2
20 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2
21 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2
22 Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer Completed NCT00381888 Phase 2
23 Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies Completed NCT01079832 Phase 2
24 Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer Recruiting NCT01764802 Phase 2
25 Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer Recruiting NCT02874430 Phase 2
26 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
27 A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma Not yet recruiting NCT02982486 Phase 2
28 Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery Completed NCT00842452 Phase 1
29 Docetaxel in Treating Patients With Refractory or Recurrent Advanced Gynecologic Cancer Completed NCT00287885 Phase 1
30 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) Completed NCT00031681 Phase 1
31 Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer Completed NCT01652794 Phase 1
32 Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00408655 Phase 1
33 PV701 in Treating Patients With Advanced or Recurrent Peritoneal Cancer Completed NCT00055705 Phase 1
34 Chemotherapy Plus Radiation Therapy in Treating Patients With Unresectable, Residual, or Recurrent Colorectal Cancer Completed NCT00003704 Phase 1
35 Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor Completed NCT00161187 Phase 1
36 Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00083213 Phase 1
37 Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00082823 Phase 1
38 Capecitabine and Radiation Therapy in Treating Patients With Locally Advanced Cervical Cancer or Other Pelvic Cancer Withdrawn NCT00118300 Phase 1
39 Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer Unknown status NCT00601406
40 Collecting Tumor Samples From Patients With Gynecological Tumors Completed NCT00897442
41 Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer Completed NCT00295945
42 Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer Completed NCT01216813
43 Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer Completed NCT01764789
44 Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients Completed NCT00253383
45 Observational Study on Endometrial Stromal Tumors Recruiting NCT02829437
46 Specimen and Data Study for Ovarian Cancer Early Detection and Prevention Recruiting NCT00005095
47 Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors Withdrawn NCT00499291

Search NIH Clinical Center for Endometrial Stromal Sarcoma

Cochrane evidence based reviews: sarcoma, endometrial stromal

Genetic Tests for Endometrial Stromal Sarcoma

Anatomical Context for Endometrial Stromal Sarcoma

MalaCards organs/tissues related to Endometrial Stromal Sarcoma:

39
Uterus, Smooth Muscle, Lung, Colon, Ovary, Breast, Lymph Node

Publications for Endometrial Stromal Sarcoma

Articles related to Endometrial Stromal Sarcoma:

(show top 50) (show all 474)
id Title Authors Year
1
Low-grade endometrial stromal sarcoma with extensive sex cord differentiation, heterologous elements, and complex atypical hyperplasia: Case report and review of literature. ( 28054022 )
2017
2
Intravenous low-grade endometrial stromal sarcoma with intracardiac extension: A CASE OF inaccurate tumor location on contrast-enhanced computed tomography. ( 26893856 )
2016
3
Low-Grade Endometrial Stromal Sarcoma with Intravenous and Intracardiac Extension: A Multidisciplinary Approach. ( 27239357 )
2016
4
Cytogenetic and Molecular Profile of Endometrial Stromal Sarcoma. ( 27219024 )
2016
5
Endometrial stromal sarcoma: An aggressive uterine malignancy. ( 27761197 )
2016
6
The application of next generation-sequencing-based molecular diagnostics in endometrial stromal sarcoma. ( 26990025 )
2016
7
Letrozole as second-line hormonal treatment for recurrent low-grade endometrial stromal sarcoma: A case report and review of the literature. ( 27895740 )
2016
8
Endobronchial metastasised endometrial stromal sarcoma. ( 26643114 )
2016
9
Endometrial Stromal Sarcoma Arising in Colorectal Endometriosis. ( 27801759 )
2016
10
An Unusual Case of YWHAE-NUTM2A/B Endometrial Stromal Sarcoma With Confinement to the Endometrium and Lack of High-Grade Morphology. ( 27171540 )
2016
11
Uterine leiomyosarcoma and endometrial stromal sarcoma have unique miRNA signatures. ( 26768834 )
2016
12
Fertility-sparing surgery for patients with low-grade endometrial stromal sarcoma. ( 27736798 )
2016
13
Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma. ( 27127168 )
2016
14
Prolonged response to exemestane following multiple surgical resections and hormonal therapies in a patient with recurrent endometrial stromal sarcoma. ( 26937477 )
2016
15
Uterine sarcoma Part II-Uterine endometrial stromal sarcoma: The TAG systematic review. ( 27590366 )
2016
16
A case of advanced-stage endometrial stromal sarcoma of the ovary arising from endometriosis. ( 27462602 )
2016
17
Novel High-grade Endometrial Stromal Sarcoma: A Morphologic Mimicker of Myxoid Leiomyosarcoma. ( 27631520 )
2016
18
Endometrioid adenocarcinoma associated with endometrial stromal sarcoma: A rare, often unrecognized collision tumor. ( 26425710 )
2015
19
Delayed osseous metastasis from low-grade endometrial stromal sarcoma: Uncommon occurrence deserving recognition. ( 26171849 )
2015
20
Long-Term Outcome of Aromatase Inhibitor Therapy With Letrozole in Patients With Advanced Low-Grade Endometrial Stromal Sarcoma. ( 26495759 )
2015
21
Endometrial Stromal Sarcoma with Intravenous and Cardiac Extension. ( 26375498 )
2015
22
Long-term treatment of residual or recurrent low-grade endometrial stromal sarcoma with aromatase inhibitors: A report of two cases and a review of the literature. ( 26722331 )
2015
23
Osteosarcoma arising from metastatic low grade endometrial stromal sarcoma. ( 25474520 )
2015
24
Vulvar extrauterine endometrial stromal sarcoma: A case report and literature review. ( 25585306 )
2015
25
Immunohistochemical panel to differentiate endometrial stromal sarcoma, uterine leiomyosarcoma and leiomyoma: something old and something new. ( 25991737 )
2015
26
Low-grade Endometrial Stromal Sarcoma Primarily Arising in the Vagina: A Case Report. ( 26592071 )
2015
27
Recurrent cerebral infarction synchronous with menorrhagia caused by endometrial stromal sarcoma. ( 26432578 )
2015
28
Ultrasonographic findings of low-grade endometrial stromal sarcoma of the uterus with a focus on cystic degeneration. ( 26537303 )
2015
29
Genomic landscape of endometrial stromal sarcoma of uterus. ( 26429873 )
2015
30
Long-term survival in low-grade endometrial stromal sarcoma with childbirth and multidisciplinary treatment: a case report. ( 26481040 )
2015
31
Effects of Morcellation of Uterine Smooth Muscle Tumor of Uncertain Malignant Potential and Endometrial Stromal Sarcoma: Case Series and Recommendations for Clinical Practice. ( 25596464 )
2015
32
Two-stage resection of a disseminated mixed endometrial stromal sarcoma and smooth muscle tumor with intravascular and intracardiac extension. ( 26701002 )
2015
33
Atypical paracaval recurrence of uterine endometrial stromal sarcoma: a case report. ( 26026102 )
2015
34
Endometrial stromal sarcoma with endometrioid adenocarcinoma of the uterus: a case report. ( 26191224 )
2015
35
Fertility-sparing treatment of low-grade endometrial stromal sarcoma. ( 26131171 )
2015
36
Influence of different treatment modalities on survival of patients with low-grade endometrial stromal sarcoma: A retrospective cohort study. ( 26449652 )
2015
37
Endometrial stromal sarcoma: a rare entity. ( 25772965 )
2015
38
Endometrial stromal sarcoma arising in colorectal endometriosis: a case report and review of the literature. ( 25648532 )
2015
39
Fibromyxoid variant of endometrial stromal sarcoma with atypical bizarre nuclei. ( 26045860 )
2015
40
Prognostic factors, treatment and outcome in a Turkish population with endometrial stromal sarcoma. ( 25735377 )
2015
41
Heart and Lung Metastases From Endometrial Stromal Sarcoma in a Forty-Two-Year-Old Woman. ( 26436070 )
2015
42
Fertility-sparing management of low-grade endometrial stromal sarcoma: analysis of an institutional series and review of the literature. ( 26476800 )
2015
43
Spontaneous Pneumothoraces due to Metastatic Endometrial Stromal Sarcoma in an HIV-infected Woman. ( 26397026 )
2015
44
Low grade endometrial stromal sarcoma: a case report. ( 25648534 )
2015
45
A Case of Metastatic Low-Grade Endometrial Stromal Sarcoma Treated with Letrozole after Ovarian Ablation by Radiotherapy. ( 25715770 )
2015
46
High grade endometrial stromal sarcoma on thinprep. ( 26174064 )
2015
47
Complete remission achieved by oophorectomy for recurrent endometrial stromal sarcoma after laparoscopic morcellation. ( 26076082 )
2015
48
Endometrial stromal sarcoma presenting as large bleeding left upper quadrant mass. ( 26605285 )
2015
49
Cyclin D1 Does Not Distinguish YWHAE-NUTM2 High-grade Endometrial Stromal Sarcoma From Undifferentiated Endometrial Carcinoma. ( 25871469 )
2015
50
Endometrial Stromal Sarcoma Metastatic from the Uterus to the Inferior Vena Cava and Right Atrium. ( 26664311 )
2015

Variations for Endometrial Stromal Sarcoma

Expression for Endometrial Stromal Sarcoma

Search GEO for disease gene expression data for Endometrial Stromal Sarcoma.

Pathways for Endometrial Stromal Sarcoma

Pathways related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.81 CCND1 CYP19A1 ESR1 TP53
2 11.44 ACTC1 DES VIM
3 11.36 CCND1 ESR1 YWHAE
4 11.06 ESR1 TP53 YWHAE
5 10.66 BCOR ESR1 YWHAE
6 10.3 CYP19A1 INHA PGR
7 9.76 CYP19A1 ESR1

GO Terms for Endometrial Stromal Sarcoma

Biological processes related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription from RNA polymerase II promoter GO:0000122 9.43 BCOR CCND1 ESR1 JAZF1 SUZ12 TP53
2 replicative senescence GO:0090399 9.32 MME TP53
3 mitotic G1 DNA damage checkpoint GO:0031571 9.26 CCND1 TP53
4 positive regulation of phospholipase C activity GO:0010863 9.16 ESR1 KIT
5 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Molecular functions related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.35 CCND1 ESR1 PGR TP53 YWHAE
2 histone deacetylase binding GO:0042826 8.92 BCOR CCND1 TP53 YWHAE

Sources for Endometrial Stromal Sarcoma

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16 ExPASy
18 FMA
28 GO
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33 ICD10
34 ICD10 via Orphanet
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