MCID: END044
MIFTS: 53

Endometriosis

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Endometriosis

MalaCards integrated aliases for Endometriosis:

Name: Endometriosis 12 29 52 41 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:289
ICD10 33 N80 N80.9
ICD9CM 35 617 617.9
MeSH 42 D004715
NCIt 47 C3014
UMLS 69 C0014175

Summaries for Endometriosis

MedlinePlus : 41 the uterus, or womb, is the place where a baby grows when a woman is pregnant. endometriosis is a disease in which the kind of tissue that normally grows inside the uterus grows outside the uterus. it can grow on the ovaries, fallopian tubes, bowels, or bladder. rarely, it grows in other parts of the body. symptoms include pain, usually in the abdomen, lower back, or pelvic areas infertility heavy periods and bleeding between periods painful menstrual cramps some women have no symptoms at all. having trouble getting pregnant may be the first sign. the cause of endometriosis is not known. surgery, usually a laparoscopy, is currently the only way to be sure that you have endometriosis. your health care provider will first take your medical history, do a pelvic exam, and maybe do imaging tests. there is no cure, but treatments help with pain and infertility. they include pain medicines, hormone treatments, and surgery. nih: national institute of child health and human development

MalaCards based summary : Endometriosis is related to endometriosis of ovary and fallopian tube endometriosis, and has symptoms including pelvic pain and pain and other symptoms associated with female genital organs. An important gene associated with Endometriosis is CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1). The drugs Calcium Carbonate and Goserelin have been mentioned in the context of this disorder. Affiliated tissues include uterus, ovary and endothelial.

Disease Ontology : 12 A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.

Wikipedia : 72 Endometriosis is a condition in which the layer of tissue that normally covers the inside of the uterus,... more...

Related Diseases for Endometriosis

Diseases in the Endometriosis family:

Endometriosis 1 Rare Endometriosis

Diseases related to Endometriosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 181)
id Related Disease Score Top Affiliating Genes
1 endometriosis of ovary 12.1
2 fallopian tube endometriosis 12.0
3 endometriosis of uterus 12.0
4 rare endometriosis 11.9
5 endometriosis of intestine 11.9
6 endometriosis of pelvic peritoneum 11.9
7 endometriosis of rectovaginal septum and vagina 11.9
8 endometriosis in scar of skin 11.8
9 cervix endometriosis 11.8
10 endometriosis 1 11.8
11 catamenial pneumothorax 11.4
12 adenomyosis 11.3
13 chronic pain 11.1
14 benign multicystic peritoneal mesothelioma 10.8
15 uterine disease 10.8
16 peritonitis 10.6
17 infertility 10.5
18 endotheliitis 10.3
19 adenocarcinoma 10.3
20 sarcoma 10.2
21 pneumothorax 10.1
22 clear cell adenocarcinoma 10.1
23 endometrial stromal sarcoma 10.1
24 adenosarcoma 10.1
25 vaginitis 10.1
26 leiomyoma 10.0
27 leiomyomatosis 10.0
28 progesterone resistance 9.9
29 intestinal obstruction 9.9
30 cervicitis 9.9
31 hydronephrosis 9.9
32 ovarian clear cell carcinoma 9.9
33 intussusception 9.9
34 pelvic inflammatory disease 9.9
35 endosalpingiosis 9.8
36 salpingitis 9.8
37 adenofibroma 9.8
38 myoma 9.8
39 ovarian clear cell adenocarcinoma 9.8
40 ureteral obstruction 9.8
41 ectopic pregnancy 9.8
42 vaginal adenosarcoma 9.8
43 breast cancer 9.8
44 cystadenoma 9.8
45 endocervicitis 9.8
46 endometrial adenocarcinoma 9.7
47 uterine fibroid 9.7
48 hypoxia 9.7
49 appendicitis 9.7
50 hepatitis 9.7

Comorbidity relations with Endometriosis via Phenotypic Disease Network (PDN):


Uterine Fibroid

Graphical network of the top 20 diseases related to Endometriosis:



Diseases related to Endometriosis

Symptoms & Phenotypes for Endometriosis

UMLS symptoms related to Endometriosis:


pelvic pain, pain and other symptoms associated with female genital organs

Drugs & Therapeutics for Endometriosis

Drugs for Endometriosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 250)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Calcium Carbonate Approved Phase 4 471-34-1
2
Goserelin Approved Phase 4,Phase 3 65807-02-5 47725 5311128
3
Tibolone Approved Phase 4 5630-53-5
4
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757
5
Drospirenone Approved Phase 4,Phase 3 67392-87-4 68873
6
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2 57-63-6 5991
7
Leuprolide Approved, Investigational Phase 4,Phase 3,Phase 2 53714-56-0 3911 657181
8
Levonorgestrel Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 797-63-7, 17489-40-6 13109
9
Anastrozole Approved, Investigational Phase 4,Phase 2,Phase 1 120511-73-1 2187
10
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 57-83-0 5994
11
Ethanol Approved Phase 4 64-17-5 702
12
Desogestrel Approved Phase 4 54024-22-5 40973
13
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3 54048-10-1 40976 6917715
14
Gestodene Approved Phase 4 60282-87-3 3033968
15
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 2,Phase 1 71-58-9
16
Danazol Approved Phase 4,Phase 2 17230-88-5 28417
17
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
18
Quinagolide Approved Phase 4 97805-50-0, 87056-78-8 105105
19
Dienogest Approved Phase 4,Phase 3,Phase 2 65928-58-7
20
Nandrolone Approved, Experimental, Illicit Phase 4,Phase 3,Phase 2 434-22-0, 62-90-8 9904 229455
21
Nandrolone decanoate Approved, Illicit Phase 4,Phase 3,Phase 2 360-70-3 9677
22
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
23
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
24
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
25
Norgestrel Approved Phase 4 6533-00-2 13109
26
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
27
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
28
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
29
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 6221 10883523 5280795
30
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
31
Sage Approved, Nutraceutical Phase 4
32 tannic acid Approved, Nutraceutical Phase 4,Phase 3
33 Gallopamil Investigational Phase 4 16662-47-8
34
Resveratrol Experimental, Investigational Phase 4 501-36-0 445154
35
Enclomiphene Investigational Phase 4 15690-57-0
36 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1
37 Bone Density Conservation Agents Phase 4,Phase 2
38 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
39 Hormones Phase 4,Phase 3,Phase 2,Phase 1
40 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
41 Micronutrients Phase 4,Phase 3,Phase 2
42 Trace Elements Phase 4,Phase 3,Phase 2
43 Vitamins Phase 4,Phase 2
44 Contraceptive Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Contraceptives, Oral Phase 4,Phase 3,Phase 2,Phase 1
46 Contraceptives, Oral, Combined Phase 4,Phase 3,Phase 2
47 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2
48 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2
49 Estradiol valerate Phase 4,Phase 3,Phase 2 979-32-8
50 Estrogens Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 325)

id Name Status NCT ID Phase Drugs
1 Randomized Study of Gonadotropin-releasing-hormone Agonist (GnRH-a) or Expectant Management for Endometriosis Unknown status NCT00654524 Phase 4 gonadotropin-releasing-hormone agonist (GnRHa) - Goserelin
2 Continuous Postoperative Use of Low-Dose Combined Oral Contraceptivesfor for Endometriosis-Related Chronic Pelvic Pain Unknown status NCT00844012 Phase 4 Continuous OC (clormadinone acetate plus ethinil-estradiol - Belara®, Grunenthal, Milan, Italy);Cyclic OC (clormadinone acetate plus ethinil-estradiol)
3 Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis Unknown status NCT02031523 Phase 4 Sanjie analgesic capsule;placebo
4 Continuous Versus Cyclic Oral Contraceptives for Endometriosis Unknown status NCT02237131 Phase 4 Oral contraceptives cyclic;Oral contraceptives continuous
5 Supplementation in Adolescent Girls With Endometriosis Completed NCT02387931 Phase 4
6 Anastrazole Plus GnRH-agonist in the Treatment of Endometriosis Recurrence Completed NCT01769781 Phase 4 anastrazole;GnRH analog alone
7 The Influence of Adjuvant Medical Treatment of Peritoneal Endometriosis on the Outcome of IVF. A Prospective Randomized Analysis. Completed NCT01682642 Phase 4 Zoladex
8 Levonorgestrel-releasing Intrauterine System in Patients With Endometriosis Completed NCT02158845 Phase 4 LNG-IUS: levonorgestrel intrauterine system;GnRHa: leuprolide
9 Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF Completed NCT00621179 Phase 4 Leuprolide acetate in depot suspension;Leuprolide acetate;leuprolide acetate
10 Homeopathic Treatment of Chronic Pelvic Pain in Women With Endometriosis Completed NCT02427386 Phase 4 dynamized estrogen;placebo
11 The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis Completed NCT01581359 Phase 4 Triptorelin acetate
12 Clinical Trial the Use of Levonorgestrel-releasing Intrauterine System Versus Etonogestrel Implant in Endometriosis Completed NCT02480647 Phase 4 Levonorgestrel;Etonogestrel
13 Efficacy of Injectable Contraceptive and Oral Contraceptive Administered After Surgical Treatment of Endometriosis With Pain Completed NCT01056042 Phase 4 intramuscular depot medroxyprogesterone acetate;ethinyl estradiol 30 micrograms, gestodene 75 micrograms
14 Resveratrol for Pain Due to Endometriosis Completed NCT02475564 Phase 4 Placebo;Resveratrol
15 Danazol Treatment in Endometriosis Women Before IVF Completed NCT01779232 Phase 4 Danazol;placebo
16 Endometriosis Patients Undergoing Quinagolide Treatment Completed NCT00625950 Phase 4
17 Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis Completed NCT00286351 Phase 4 Combined treatment with Arimidex and Zoladex before IVF
18 Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women Completed NCT00735852 Phase 4 Decapeptyl SR 11.25mg
19 Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients Completed NCT02534688 Phase 4 LNG-IUS;DMPA
20 Study to Compare Peritoneal Ablation by Excision Only and Excision With the Use of an Adhesion Barrier Recruiting NCT02165917 Phase 4
21 Induction of Ovulation by Clomiphene Citrate Following Laparoscopic Surgery for Endometriosis Stage 1 and Stage 2 With and Without Suppression by Dienogest Recruiting NCT02575248 Phase 4 Dienogest 2mg;Clomiphene citrate 5 mg
22 Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery Recruiting NCT02385448 Phase 4 Dienogest;Microgynon
23 Chronic Pain Risk Associated With Menstrual Period Pain Recruiting NCT02214550 Phase 4 microgestin 1/20
24 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Recruiting NCT02812186 Phase 4 Rocuronium
25 Ulipristal for Endometriosis-related Pelvic Pain Active, not recruiting NCT02213081 Phase 4 Ulipristal
26 Estimation of Vascularization After Treatment of Deep Rectovaginal Endometriosis Node by Rectal Shaving Not yet recruiting NCT03080558 Phase 4 Indocyanine green
27 Psychological Impact of Amenorrhea in Women With Endometriosis Not yet recruiting NCT02393482 Phase 4 Estroprogestinic therapy (Etinil-estradiol/levonorgestre);Gonadotropin-releasing hormone agonist (Leuprorelin acetate);Add back therapy 1 (tibolone);Add back therapy 2 (calcium carbonate/colecalciferol)
28 Pituitary Down-regulation Before IVF for Women With Endometriosis Terminated NCT01757249 Phase 4 Combined Oral Contraceptive Pill (Microgynon 30)
29 Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions Terminated NCT01344486 Phase 4
30 Maintenance Therapy of Levonorgestrel-releasing Intrauterine System (LNG-IUS) to Prevent the Recurrence of Symptomatic Endometriosis After Conservative Surgery Unknown status NCT01125488 Phase 3 GnRH agonist (triptorelin)
31 Laparoscopy Versus Laparotomy for Colorectal Endometriosis Unknown status NCT00939861 Phase 3
32 Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg) Unknown status NCT00458458 Phase 3 Norethindrone Acetate (NA);GnRH Agonist (Lupron Depot)
33 The In Vitro Fertilization - Lipiodol Uterine Bathing Effect Study Unknown status NCT00894946 Phase 3
34 The Results of Preimplantation Genetic Diagnosis and Preimplantation Genetic Screening of Embryos Obtained From GnRH-agonist Long and GnRH-antagonist Ovarian Stimulation Protocol Unknown status NCT01636505 Phase 3 ghrh antagonist (cetrotide/orgalutran);gnrh agonist (suprefact)
35 Understanding Experimentally Induced Hot Flushes Unknown status NCT00455689 Phase 2, Phase 3 Leuprolide acetate (Lupron)
36 Phase 3 Study of Dienogest for the Treatment of Endometriosis in Chinese Patients Completed NCT01822080 Phase 3 Dienogest (Visanne, BAY86-5258);Placebo
37 Mifepristone 2.5, 5, 10 mg Versus Placebo in the Treatment of Endometriosis Completed NCT02271958 Phase 2, Phase 3 Mifepristone;PLACEBO
38 Global Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-associated Pain Completed NCT02143713 Phase 3 Elagolix
39 A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain Completed NCT01620528 Phase 3 Elagolix
40 A Global Phase 3 Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain Completed NCT01931670 Phase 3 Elagolix
41 Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain Completed NCT01760954 Phase 3 Elagolix
42 Degarelix in the Treatment of Endometriosis Recurrence Completed NCT01712763 Phase 3 degarelix;goserelin
43 Pentoxifylline and Endometriosis Completed NCT00632697 Phase 3 pentoxifylline;placebo
44 Medical Treatment of Endometriosis-Associated Pelvic Pain Completed NCT00229996 Phase 3 Oral Contraceptive;Depot-Leuprolide/Norethindrone
45 Safety and Efficacy of SH T00660AA in Treatment of Endometriosis Completed NCT00225186 Phase 3 Visanne (SH T00660AA , BAY86-5258)
46 Efficacy and Safety of SH T00660AA in Treatment of Endometriosis Completed NCT00225199 Phase 3 Visanne (BAY86-5258, SH T00660AA);Placebo
47 Comparative Study of BAY86-5300 With an Extended Flexible Regimen for Endometriosis Completed NCT01697111 Phase 3 EE20/DRSP(BAY86-5300);Placebo;Dienogest
48 The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic Endometriosis Completed NCT00455845 Phase 3
49 Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With Endometriosis Completed NCT00902746 Phase 3 NPC-01
50 Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrhea Completed NCT00212342 Phase 3 Norethisterone,Ethinylestradiol;Sugar pill

Search NIH Clinical Center for Endometriosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: endometriosis

Genetic Tests for Endometriosis

Genetic tests related to Endometriosis:

id Genetic test Affiliating Genes
1 Endometriosis 29

Anatomical Context for Endometriosis

MalaCards organs/tissues related to Endometriosis:

39
Uterus, Ovary, Endothelial, Testes, Monocytes, Smooth Muscle, Neutrophil

Publications for Endometriosis

Articles related to Endometriosis:

(show top 50) (show all 2598)
id Title Authors Year
1
Ethinylestradiol 20A I1g/drospirenone 3A mg in a flexible extended regimen for the management of endometriosis-associated pelvic pain: a randomized controlled trial. ( 28911925 )
2017
2
Aberrant endometrial DNA methylome of homeobox A10 and catechol-O-methyltransferase in endometriosis. ( 28074437 )
2017
3
Aberrant expression of epithelial leucine-rich repeat containing G protein-coupled receptor 5-positive cells in the eutopic endometrium in endometriosis and implications in deep-infiltrating endometriosis. ( 28923287 )
2017
4
The experience of illness of women with endometriosis: narratives about institutional violence. ( 28954153 )
2017
5
Use of medroxyprogesterone acetate in women with ovarian endometriosis undergoing controlled ovarian hyperstimulation for in vitro fertilization. ( 28931865 )
2017
6
Endometriosis in the setting of Muckle-Wells syndrome treated with an IL-1I^ antagonist. ( 28508753 )
2017
7
CA 125 Relatively Specific for Diagnosing Endometriosis. ( 28084702 )
2017
8
Effect of simvastatin on monocyte chemoattractant protein-1 expression in endometriosis patients: a randomized controlled trial. ( 28950844 )
2017
9
Plasma urocortin-1 as a preoperative marker of endometriosis in symptomatic women. ( 28925754 )
2017
10
Intrafollicular inflammatory cytokines but not steroid hormone concentrations are increased in naturally matured follicles of women with proven endometriosis. ( 28074436 )
2017
11
Oral and depot progestin therapy for endometriosis: towards a personalized medicine. ( 28914561 )
2017
12
Primary Amenorrhea and Endometriosis Secondary to an Unusual MA1llerian Anomaly. ( 28461177 )
2017
13
Reply: Should we also work on an international informed consent for endometriosis surgery? ( 28043943 )
2017
14
Development of abdominal wall endometriosis in a region distant from a caesarean section scar. ( 28052369 )
2017
15
Deep Infiltrating Endometriosis and Endometrial Adenocarcinoma Express High Levels of Myostatin and Its Receptors Messenger RNAs. ( 28345488 )
2017
16
Scar endometriosis: an entity not to be forgotten. ( 28065974 )
2017
17
Evaluation of Circulating Endometrial Cells as a Biomarker for Endometriosis. ( 28937041 )
2017
18
Is cytochrome P450 3A4 regulated by menstrual cycle hormones in control endometrium and endometriosis? ( 27995413 )
2017
19
KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance. ( 28754906 )
2017
20
Revisiting the wandering womb: Oxytocin in endometriosis and bipolar disorder. ( 28919554 )
2017
21
Higher prevalence of chronic endometritis in women with endometriosis: a possible etiopathogenetic link. ( 28624114 )
2017
22
Abnormal peritoneal regulation of chemokine activation-The role of IL-8 in pathogenesis of endometriosis. ( 28120482 )
2017
23
Smad3/4 Binding to Promoter II of P450arom So As to Regulate Aromatase Expression in Endometriosis. ( 27920344 )
2017
24
Baicalein reduces endometriosis by suppressing the viability of human endometrial stromal cells through the nuclear factor-I_B pathway in vitro. ( 28912852 )
2017
25
Behavioral, cognitive, and emotional coping strategies of women with endometriosis: a critical narrative review. ( 28932912 )
2017
26
Extrauterine Adenomyoma of the Liver in a 50 year old Female with Pelvic Endometriosis. ( 28442524 )
2017
27
Association between X-ray repair cross-complementing group 1(XRCC1) Arg399Gln polymorphism and endometriosis: A systematic review and meta-analysis. ( 28926725 )
2017
28
Cancer Implications for Patients with Endometriosis. ( 28049216 )
2017
29
Combined effect of vascular endothelial growth factor and its receptor polymorphisms in endometriosis: a case-control study. ( 27836223 )
2017
30
Reply to Rodolfo Montironi, Silvia Gasparrini, Antonio Lopez-Beltran, et al's Letter to the Editor re: Umberto Leone Roberti Maggiore, Simone Ferrero, Massimo Candiani, et al. Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation. Eur Urol 2017;71:790-807. Benign MA1llerian Lesions in the Urinary Bladder: Endometriosis, Endocervicosis, Endosalpingiosis, and MA1llerianosis. ( 28583309 )
2017
31
Estrogen stabilizes hypoxia-inducible factor 1I+ through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis. ( 27939762 )
2017
32
Does preoperative antimA1llerian hormone level influence postoperative pregnancy rate in women undergoing surgery for severe endometriosis? ( 28089574 )
2017
33
Mannose receptor is highly expressed by peritoneal dendritic cells in endometriosis. ( 27793384 )
2017
34
The role of the B lymphocytes in endometriosis: A systematic review. ( 28910679 )
2017
35
Ultrasound Imaging for Ovarian and Deep Infiltrating Endometriosis. ( 28076877 )
2017
36
A Case with Severe Endometriosis, Ovarian Hyperstimulation Syndrome, and Isolated Unilateral Pleural Effusion after IVF. ( 28770117 )
2017
37
Progesterone resistance in endometriosis: origins, consequences and interventions. ( 28423456 )
2017
38
Oxidative Stress Statues in Serum and Follicular Fluid of Women with Endometriosis. ( 28042542 )
2017
39
Should we also work on an international informed consent for endometriosis surgery? ( 28043944 )
2017
40
Cancer-Associated Mutations in Endometriosis without Cancer. ( 28489996 )
2017
41
Catamenial pneumothorax revealing diaphragmatic endometriosis: a case report and revue of literature. ( 28819533 )
2017
42
Association of the protein tyrosine phosphatase non-receptor 22 polymorphism (PTPN22) with endometriosis: a meta-analysis. ( 28444099 )
2017
43
Immunosuppressive macrophages induced by IDO1 promote the growth of endometrial stromal cells in endometriosis. ( 28260094 )
2017
44
The role of TGF-I^ in the pathophysiology of peritoneal endometriosis. ( 28903471 )
2017
45
Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study. ( 28915409 )
2017
46
The association between interleukin-10 (IL-10) -592C/A, -819T/C, -1082G/A promoter polymorphisms and endometriosis. ( 28004192 )
2017
47
Anisakiasis and intestinal endometriosis: under-recognized conditions in the differential diagnosis of acute abdomen. ( 28004963 )
2017
48
Conservative treatment of deep infiltrating endometriosis: review of existing options. ( 28952821 )
2017
49
Significance of Ovarian Endometriosis on the Prognosis of Ovarian Clear Cell Carcinoma. ( 28930811 )
2017
50
Management of ureteral endometriosis with hydronephrosis: Experience from a tertiary medical center. ( 28707816 )
2017

Variations for Endometriosis

Expression for Endometriosis

LifeMap Discovery
Genes differentially expressed in tissues of Endometriosis patients vs. healthy controls: 35 (show top 50) (show all 83)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1 PTGIS prostaglandin I2 (prostacyclin) synthase Uterus + 5.41 0.000
2 MYH11 myosin, heavy chain 11, smooth muscle Uterus + 4.87 0.001
3 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide Uterus + 4.81 0.000
4 CNN1 calponin 1, basic, smooth muscle Uterus + 4.71 0.000
5 TAGLN transgelin Uterus + 4.63 0.000
6 PAEP progestagen-associated endometrial protein Uterus + 4.63 0.013
7 PRELP proline/arginine-rich end leucine-rich repeat protein Uterus + 4.59 0.000
8 C7 complement component 7 Uterus + 4.54 0.003
9 ACTG2 actin, gamma 2, smooth muscle, enteric Uterus + 4.48 0.003
10 TCF21 transcription factor 21 Uterus + 4.45 0.000
11 HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) Uterus - 4.42 0.001
12 WISP2 WNT1 inducible signaling pathway protein 2 Uterus + 4.11 0.001
13 AQP1 aquaporin 1 (Colton blood group) Uterus + 4.10 0.000
14 EHF ets homologous factor Uterus - 4.10 0.000
15 FOS FBJ murine osteosarcoma viral oncogene homolog Uterus + 4.09 0.000
16 FOSB FBJ murine osteosarcoma viral oncogene homolog B Uterus + 4.07 0.000
17 SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 Uterus - 4.05 0.010
18 LMNB1 lamin B1 Uterus - 4.05 0.000
19 SLC26A4 solute carrier family 26 (anion exchanger), member 4 Uterus - 3.99 0.000
20 DPT dermatopontin Uterus + 3.98 0.000
21 DES desmin Uterus + 3.97 0.001
22 KCNMB1 potassium channel subfamily M regulatory beta subunit 1 Uterus + 3.96 0.001
23 GATA6 GATA binding protein 6 Uterus + 3.89 0.004
24 FZD7 frizzled class receptor 7 Uterus + 3.89 0.000
25 LEFTY2 left-right determination factor 2 Uterus + 3.88 0.001
26 SLC26A4 solute carrier family 26 (anion exchanger), member 4 Uterus - 3.87 0.001
27 HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) Uterus - 3.86 0.001
28 ACKR1 atypical chemokine receptor 1 (Duffy blood group) Uterus + 3.84 0.001
29 EFHC2 EF-hand domain (C-terminal) containing 2 Uterus - 3.75 0.000
30 PDLIM3 PDZ and LIM domain 3 Uterus + 3.72 0.001
31 GPC3 glypican 3 Uterus + 3.71 0.003
32 IL20RA interleukin 20 receptor, alpha Uterus - 3.70 0.000
33 MYL9 myosin, light chain 9, regulatory Uterus + 3.70 0.001
34 VNN1 vanin 1 Uterus - 3.69 0.008
35 CTSZ cathepsin Z Uterus - 3.68 0.000
36 EHF ets homologous factor Uterus - 3.67 0.000
37 LMNB1 lamin B1 Uterus - 3.61 0.000
38 CLU clusterin Uterus + 3.58 0.002
39 ACTA2 actin, alpha 2, smooth muscle, aorta Uterus + 3.57 0.000
40 TCEAL2 transcription elongation factor A (SII)-like 2 Uterus + 3.53 0.001
41 LMOD1 leiomodin 1 (smooth muscle) Uterus + 3.52 0.003
42 LMO3 LIM domain only 3 (rhombotin-like 2) Uterus + 3.51 0.002
43 TPD52 tumor protein D52 Uterus - 3.50 0.000
44 SYNPO synaptopodin Uterus + 3.48 0.001
45 KLF2 Kruppel-like factor 2 Uterus + 3.44 0.000
46 AOC3 amine oxidase, copper containing 3 Uterus + 3.44 0.003
47 KCNK3 potassium channel, two pore domain subfamily K, member 3 Uterus + 3.44 0.007
48 ZBBX zinc finger, B-box domain containing Uterus - 3.43 0.001
49 FMO1 flavin containing monooxygenase 1 Uterus + 3.43 0.000
50 ZBBX zinc finger, B-box domain containing Uterus - 3.42 0.002
Search GEO for disease gene expression data for Endometriosis.

Pathways for Endometriosis

GO Terms for Endometriosis

Sources for Endometriosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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