Aliases & Classifications for Enophthalmos

MalaCards integrated aliases for Enophthalmos:

Name: Enophthalmos 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11175
ICD10 33 H05.4 H05.40
ICD9CM 35 376.5 376.50
MeSH 42 D015841
NCIt 47 C79552
UMLS 69 C0014306

Summaries for Enophthalmos

MalaCards based summary : Enophthalmos is related to silent sinus syndrome and horner's syndrome. An important gene associated with Enophthalmos is TFAP2A (Transcription Factor AP-2 Alpha). The drugs Bone Density Conservation Agents and Calcium, Dietary have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and breast, and related phenotype is Decreased shRNA abundance (Z-score < -2).

Wikipedia : 72 Enophthalmos is the posterior displacement of the eyeball within the orbit due to changes in the volume... more...

Related Diseases for Enophthalmos

Graphical network of the top 20 diseases related to Enophthalmos:



Diseases related to Enophthalmos

Symptoms & Phenotypes for Enophthalmos

GenomeRNAi Phenotypes related to Enophthalmos according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.17 EPB41L1 TFAP2A
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.17 TFAP2A
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.17 TFAP2A
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-55 9.17 EPB41L1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.17 EPB41L1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.17 EPB41L1

Drugs & Therapeutics for Enophthalmos

Drugs for Enophthalmos (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Bone Density Conservation Agents Phase 2
2 Calcium, Dietary Phase 2
3
Cocaine Approved, Illicit 50-36-2 5760 446220
4 Anesthetics

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Polycaprolactone / Tricalcium Phosphate (PCL/TCP) v Titanium Orbital Implant : Randomised Trial Unknown status NCT01119144 Phase 2
2 Reconstruction of the Orbit With a Bioresorbable Polycaprolactone Implant Completed NCT00233922 Phase 2
3 Use of a Low Profile Titanium Mesh in Orbital Reconstruction Completed NCT01432964

Search NIH Clinical Center for Enophthalmos

Cochrane evidence based reviews: enophthalmos

Genetic Tests for Enophthalmos

Anatomical Context for Enophthalmos

MalaCards organs/tissues related to Enophthalmos:

39
Eye, Bone, Breast, Brain

Publications for Enophthalmos

Articles related to Enophthalmos:

(show top 50) (show all 262)
id Title Authors Year
1
Differences in interpalpebral fissure measurement in patients with unilateral enophthalmos resulting from orbital wall fractures. ( 28344027 )
2017
2
Secondary Reconstruction of Posttraumatic Enophthalmos with Titanium Mesh and Buccal Fat Pad Graft: Case Report. ( 28825031 )
2017
3
Comments on "A Straightforward Method of Predicting Enophthalmos in Blowout Fractures Using Enophthalmos Estimate Line". ( 28279685 )
2017
4
Prediction of Late Enophthalmos Using Preoperative Orbital Volume and Fracture Area Measurements in Blowout Fracture. ( 28834836 )
2017
5
Enophthalmos and Hemifacial Skeletal Atrophy After Trigeminal Nerve Injury. ( 26784553 )
2016
6
Sliced Costochondral Chip Grafts in Posttraumatic Enophthalmos Correction. ( 28027179 )
2016
7
Predicting late enophthalmos: Differences between medial and inferior orbital wall fractures. ( 27769606 )
2016
8
Periorbital and Orbital Aging: Senile Enophthalmos as a Cause of Upper Eyelid Ptosis. ( 27348683 )
2016
9
Metastatic Scirrhous Breast Carcinoma to Orbit Causing Enophthalmos. ( 27342331 )
2016
10
Antral bony wall erosion, trigeminal nerve injury, and enophthalmos after root canal surgery. ( 27465790 )
2016
11
The Correlation between the Orbital Volume Ratio and Enophthalmos in Unoperated Blowout Fractures. ( 27896181 )
2016
12
Surgical correction of severe enophthalmos caused by bullet injury. ( 27723646 )
2016
13
Orbital Volume Augmentation for Enophthalmos Following Ventriculoperitoneal Shunting: A Case Study in "Silent Brain Syndrome". ( 26866332 )
2016
14
The imploding antrum: An unusual case of nontraumatic painless enophthalmos. ( 27905348 )
2016
15
Linear scleroderma en coup de sabre presenting with positional diplopia and enophthalmos. ( 27754909 )
2016
16
A Straightforward Method of Predicting Enophthalmos in Blowout Fractures Using Enophthalmos Estimate Line. ( 27542546 )
2016
17
Prediction of the development of late enophthalmos in pure blowout fractures: delayed orbital tissue atrophy plays a major role. ( 27198642 )
2016
18
Secondary Reconstruction of Residual Enophthalmos Using an Endoscope and Considering the Orbital Floor and Medial Wall Slope. ( 27244206 )
2016
19
Can customized implants correct enophthalmos and delayed diplopia in post-traumatic orbital deformities? A volumetric analysis. ( 27157630 )
2016
20
Correction of Late Posttraumatic Enophthalmos Using an Antral Balloon. ( 26080197 )
2015
21
Prostaglandin-Associated Enophthalmos: An Observer-Masked Radiological Study of Patients Treated with Prostaglandin Drops to One Eye Only. ( 26540119 )
2015
22
Enophthalmos and choroidal atrophy after intraophthalmic artery chemotherapy for retinoblastoma. ( 25439599 )
2015
23
Pulsatile enophthalmos, severe esotropia, kinked optic nerve and visual loss in neurofibromatosis type-1. ( 26903735 )
2015
24
Acquired enophthalmos with systemic lupus erythematosus. ( 26306741 )
2015
25
Posttraumatic Delayed Enophthalmos: Analogies with Silent Sinus Syndrome? Case Report and Literature Review. ( 26269736 )
2015
26
Retracting Globe: Enophthalmos and Retraction Due to an Accessory Extraocular Muscle. ( 25714085 )
2015
27
Hyaluronic Acid Gel Re-Injection for Enophthalmos Correction in Silent Sinus Syndrome. ( 26516690 )
2015
28
Association of Titanium Mesh and Bovine Pericardium Membrane in the Treatment of Severe Enophthalmos. ( 26468837 )
2015
29
Silent sinus syndrome as a recognised cause of unilateral painless enophthalmos. ( 24859556 )
2014
30
The temporoparietal adipofascial flap for the correction of recurrent idiopathic enophthalmos. ( 24621720 )
2014
31
Isolated enophthalmos: an uncommon gateway to orbital tumors in pediatrics: 9 month-old female presenting with isolated enophthalmos as the unique sign of a metastatic orbital tumor: a case report. ( 25248293 )
2014
32
Titanium screw entered into maxillary sinus: a rare incident during rigid fixation of the porous polyethylene implant in enophthalmos correction. ( 25006927 )
2014
33
Intra-operative navigation for orbital reconstruction to correct diplopia and enophthalmos with endoscopic assisted technique: first case report in Thailand. ( 25536718 )
2014
34
Correction of severe enophthalmos by simultaneous fat grafting and anatomic orbital reconstruction. ( 25203579 )
2014
35
Retroseptal lipotransfer to correct enophthalmos in the postraumatic amaurotic eye. ( 25415124 )
2014
36
Swelling of the inferior rectus muscle and enophthalmos in orbital floor fracture. ( 23524790 )
2013
37
Secondary repair of acquired enophthalmos. ( 24138742 )
2013
38
Measurement of fracture size using the picture archiving communication system in an outpatient clinic for factors that influence postoperative enophthalmos in adult inferior orbital wall fractures. ( 24036755 )
2013
39
Enophthalmos as a sign of metastatic breast carcinoma. ( 23460637 )
2013
40
Pulsating enophthalmos in neurofibromatosis 1. ( 23478791 )
2013
41
The Correlation between the Degree of Enophthalmos and the Extent of Fracture in Medial Orbital Wall Fracture Left Untreated for Over Six Months: A Retrospective Analysis of 81 Cases at a Single Institution. ( 23898428 )
2013
42
The coming age of enophthalmos. ( 23872815 )
2013
43
Surgical management of enophthalmos in Duane syndrome. ( 23524730 )
2013
44
Diplopia and enophthalmos in blowout fractures. ( 22777445 )
2012
45
A paradigm shift in correcting medial orbital fracture-related enophthalmos: volumetric augmentation through a lateral approach. ( 22565899 )
2012
46
Orbitozygomatic fractures with enophthalmos: analysis of 64 cases treated late. ( 21752509 )
2012
47
Correction of posttraumatic enophthalmos. ( 22783485 )
2012
48
Frontoethmoidal mucocele presenting as progressive enophthalmos. ( 22670079 )
2012
49
Development and demonstration of a novel computer planning solution for predefined correction of enophthalmos in anophthalmic patients using prebended 3D titanium-meshes--a technical note. ( 23078825 )
2012
50
Surgical treatment of enophthalmos using an endoscope and T-shaped porous polyethylene fabricated with a mirror image. ( 22858345 )
2012

Variations for Enophthalmos

Expression for Enophthalmos

Search GEO for disease gene expression data for Enophthalmos.

Pathways for Enophthalmos

GO Terms for Enophthalmos

Sources for Enophthalmos

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
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59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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