MCID: ENT001
MIFTS: 31

Enterocele

Categories: Gastrointestinal diseases, Reproductive diseases

Aliases & Classifications for Enterocele

Summaries for Enterocele

MalaCards based summary : Enterocele, also known as vaginal enterocele, is related to congenital diaphragmatic hernia and hiatus hernia. An important gene associated with Enterocele is CD9 (CD9 Molecule). The drugs Cefuroxime and Menthol have been mentioned in the context of this disorder. Affiliated tissues include small intestine and colon, and related phenotype is Decreased HIV-LTR-beta-galactosidase protein expression.

Wikipedia : 72 An enterocele or enterocoele is a protrusion of the small intestines and peritoneum into the vaginal... more...

Related Diseases for Enterocele

Diseases related to Enterocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
id Related Disease Score Top Affiliating Genes
1 congenital diaphragmatic hernia 12.4
2 hiatus hernia 12.3
3 inguinal hernia 12.3
4 umbilical hernia 12.2
5 diaphragmatic hernia 3 12.0
6 hernia of ovary and fallopian tube 11.8
7 acromegaloid features, overgrowth, cleft palate, and hernia 11.7
8 microspherophakia with hernia 11.7
9 dih1-related congenital diaphragmatic hernia 11.7
10 spigelian hernia-cryptorchidism syndrome 11.7
11 marfanoid habitus-inguinal hernia-advanced bone age syndrome 11.7
12 lethal hydranencephaly-diaphragmatic hernia syndrome 11.7
13 diverticulosis of bowel, hernia, and retinal detachment 11.7
14 arthrogryposis multiplex with deafness, inguinal hernias, and early death 11.7
15 dandy-walker malformation with nasopharyngeal teratoma and diaphragmatic hernia 11.7
16 diaphragmatic hernia exomphalos corpus callosum agenesis 11.7
17 diaphragmatic hernia upper limb defects 11.7
18 hydrocephaly corpus callosum agenesis diaphragmatic hernia 11.7
19 donnai-barrow syndrome 11.6
20 fryns syndrome 11.6
21 shprintzen-goldberg syndrome 11.5
22 galloway-mowat syndrome 11.5
23 short syndrome 11.5
24 abdominal wall defect 11.4
25 persistent mullerian duct syndrome 11.4
26 microphthalmia, syndromic 12 11.4
27 pagod syndrome 11.3
28 lambert syndrome 11.3
29 smith-kingsmore syndrome 11.3
30 chromosome 8p23.1 deletion 11.0
31 displacement of cardia through esophageal hiatus 11.0
32 hydrocele 11.0
33 vaginitis 10.5
34 bleeding disorder, platelet-type, 16, autosomal dominant 10.2 CD9 F2
35 autonomic neuropathy 10.1 F2 PVR
36 prostate malignant phyllodes tumor 9.9 F2 PVR
37 cervicitis 9.8
38 intestinal obstruction 9.8
39 intussusception 9.8
40 rectal prolapse 9.8
41 cystitis 9.7
42 endometriosis 9.7
43 solitary rectal ulcer syndrome 9.7
44 peritonitis 9.7
45 lymphoma 9.7
46 interstitial cystitis 9.7
47 rectal disease 6.6 BRD2 CD9 CMKLR1 ENSG00000278815 F2 PPAN
48 thyroid crisis 5.9 BRD2 CD9 CMKLR1 ENSG00000278815 F2 IDUA

Graphical network of the top 20 diseases related to Enterocele:



Diseases related to Enterocele

Symptoms & Phenotypes for Enterocele

GenomeRNAi Phenotypes related to Enterocele according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased HIV-LTR-beta-galactosidase protein expression GR00224-A-1 8.8 CMKLR1 F2 MMP13

Drugs & Therapeutics for Enterocele

Drugs for Enterocele (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefuroxime Approved 55268-75-2 5361202 5479529
2
Menthol Approved 2216-51-5 16666
3 Anti-Bacterial Agents
4 Antibiotics, Antitubercular
5 Anti-Infective Agents
6 cefuroxime axetil

Interventional clinical trials:

(show all 12)

id Name Status NCT ID Phase Drugs
1 Clinical Outcomes and Urodynamic Effects After Vaginal Tailored Mesh Surgery for Pelvic Organ Prolapse Completed NCT02178735 Phase 4
2 Clinical Performance of the GYNECARE PROLIFT + M* Pelvic Floor Repair System as a Device for Pelvic Organ Prolapse Completed NCT00833001 Phase 2, Phase 3
3 Prophylactic Antibiotic Treatment During Vaginal Repair Unknown status NCT00162604 Cefuroxime
4 Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year Completed NCT00774215
5 Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients Completed NCT02239302
6 Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products Completed NCT00388947
7 Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse Completed NCT00223106
8 SCP vs HUSLS for Pelvic Organ Prolapse Repair Recruiting NCT02800512
9 Restorelle® Mesh Versus Native Tissue Repair for Prolapse Recruiting NCT02162615
10 Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse Active, not recruiting NCT01097200
11 Anterior Versus Posterior Laparoscopic Mesh Rectopexy For Rectal Prolapse; a Randomized Controlled Trial. Not yet recruiting NCT03026738
12 Exair® Versus Native Tissue Repair for Prolapse Terminated NCT02162628

Search NIH Clinical Center for Enterocele

Cochrane evidence based reviews: hernia

Genetic Tests for Enterocele

Anatomical Context for Enterocele

MalaCards organs/tissues related to Enterocele:

39
Small Intestine, Colon

Publications for Enterocele

Articles related to Enterocele:

(show top 50) (show all 132)
id Title Authors Year
1
Rectal axis and enterocele on proctogram may predict laparoscopic ventral mesh rectopexy outcomes for rectal intussusception. ( 28674947 )
2017
2
Temporary successful results of ventral rectopexy for enterocele surgical correction, about 138 patients. ( 28803377 )
2017
3
Robot-assisted versus laparoscopic ventral rectopexy for external, internal rectal prolapse and enterocele: a randomised controlled trial. ( 26919191 )
2016
4
The Manchester-Fothergill and the Elevate PosteriorAr technique for the correction of a cervical elongation and large enterocele in a patient with bladder exstrophy and multiple surgeries. ( 25578871 )
2015
5
Aggressive angiomyxoma of rectovaginal septum, mimicking a huge recto-enterocele: a rare case report. ( 24757344 )
2014
6
Urogynecological prolapse and enterocele are predictive of poor functional outcome after failed or complicated STARR procedures. ( 24691768 )
2014
7
Laparoscopic repair of recurrent lateral enterocele and rectocele. ( 25224146 )
2014
8
Entero-colpo-defecography vs supine entero-MRI: which one is the best tool in the differentiation of enterocele, elytrocele and edrocele? ( 24152850 )
2013
9
[Enterocele containing cecum and terminal ileum at labium majus level]. ( 24094927 )
2013
10
The TRAM dam design: a new method for treatment of an enterocele. ( 22124762 )
2012
11
Symptomatic vaginal enterocele associated with malfunctioning ventriculoperitoneal shunt and cerebrospinal ascites. ( 21487828 )
2011
12
Enterocele is not a contraindication to stapled transanal surgery for outlet obstruction: an analysis of 170 patients. ( 21564465 )
2011
13
Laparoscopic correction of enterocele associated to stapled transanal rectal resection for obstructed defecation syndrome. ( 19921222 )
2010
14
Role of enterocele in the obstructed defecation syndrome (ODS): a new radiological point of view. ( 19788492 )
2010
15
Small bowel incarceration associated with posthysterectomy enterocele. ( 19855912 )
2010
16
Rare cause of intestinal obstruction - Vaginal enterocele. ( 23133218 )
2010
17
Enterocele--diagnosis and treatment. ( 19200673 )
2009
18
Transvaginal pelvic organ prolapse repair of anterior enterocele following cystectomy in females. ( 19089305 )
2009
19
Rectal prolapse, rectal intussusception, rectocele, solitary rectal ulcer syndrome, and enterocele. ( 18794001 )
2008
20
Symptomatic enterocele. An unusual presentation of chylous ascites and lymphoma. ( 18239020 )
2008
21
A comparison of dynamic transperineal ultrasound (DTP-US) with dynamic evacuation proctography (DEP) in the diagnosis of cul de sac hernia (enterocele) in patients with evacuatory dysfunction. ( 18256847 )
2008
22
Enterocele repair by abdominal obliteration of the pelvic inlet: long-term outcome on obstructed defaecation and symptoms of pelvic discomfort. ( 17608820 )
2007
23
Anatomy of the sigmoid colon, rectum, and the rectovaginal pouch in women with enterocele and anterior rectal wall procidentia. ( 16287126 )
2006
24
Laparoscopic vaginal vault suspension and enterocele repair. ( 16920116 )
2006
25
Transvaginal repair of enterocele and vaginal vault prolapse using autologous fascia lata graft. ( 16817089 )
2006
26
Enterocele: what is the clinical implication? ( 17106819 )
2006
27
Obliteration of the pelvic inlet by prophylene mesh and omentoplasty for enterocele. ( 16969606 )
2006
28
Stapled transanal rectal resection under laparoscopic surveillance for rectocele and concomitant enterocele. ( 16583290 )
2006
29
Enterocele associated with rectocele revealed by dynamic pelvic CT. ( 15803223 )
2005
30
Metastatic colon carcinoma found within an enterocele sac: a case report. ( 15647967 )
2005
31
Bilateral iliococcygeal fixation for vaginal vault prolapse and enterocele repair using a new suturing device--the digital needle driver. ( 16045532 )
2005
32
Posterior compartment prolapse on two-dimensional and three-dimensional pelvic floor ultrasound: the distinction between true rectocele, perineal hypermobility and enterocele. ( 15973648 )
2005
33
Transection of a colonic diverticulum during enterocele repair. ( 15663145 )
2004
34
Severe intra-abdominal bleeding following stapled mucosectomy due to enterocele: report of a case. ( 15057589 )
2004
35
The pathophysiology of an enterocele and its management. ( 15203582 )
2004
36
Anterior enterocele: a report of three cases. ( 15278250 )
2004
37
Laparoscopic treatment of enterocele: a 3-year evaluation. ( 15089832 )
2004
38
Commentary on: "Posterior culdeplasty: surgical correction of enterocele during vaginal hysterectomy: A preliminary report". 1957. ( 12681861 )
2003
39
Diagnosis of posterior enterocele: comparison of rectal ultrasonography with intraoperative diagnosis. ( 11934095 )
2002
40
Treatment of enterocele by abdominal colporectosacropexy - efficacy on pelvic pressure. ( 12780575 )
2002
41
Enterocele: is there a histologic defect? ( 11576580 )
2001
42
High uterosacral vaginal vault suspension with fascial reconstruction for vaginal repair of enterocele and vaginal vault prolapse. ( 11744906 )
2001
43
Vaginal vault suspension and enterocele repair by Richardson-Saye laparoscopic technique: description of training technique and results. ( 11303992 )
2001
44
Functional and anatomic follow-up of enterocele repairs. ( 11506843 )
2001
45
Vaginal vault fixation and prevention of enterocele recurrence by high midline levator myorraphy: physical examination and questionnaire-based follow-up. ( 11805411 )
2001
46
Combined abdominoperineal repair of enterocele and rectocele. ( 11862573 )
2001
47
Repair of enterocele and vault prolapse: transvaginal culdosuspension. ( 11383993 )
2001
48
Enterocele repair and vaginal vault suspension. ( 10954154 )
2000
49
Treatment of enterocele by obliteration of the pelvic inlet. ( 10813137 )
2000
50
Clinical presentation of enterocele. ( 11004366 )
2000

Variations for Enterocele

Expression for Enterocele

Search GEO for disease gene expression data for Enterocele.

Pathways for Enterocele

GO Terms for Enterocele

Biological processes related to Enterocele according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of fat cell differentiation GO:0045600 8.62 CMKLR1 WDFY2

Sources for Enterocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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