MCID: ENT007
MIFTS: 26

Enteropathica malady

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Enteropathica

About this section

Aliases & Descriptions for Enteropathica:

Name: Enteropathica 48

Classifications:



Summaries for Enteropathica

About this section
MalaCards based summary: Enteropathica is related to acrodermatitis enteropathica and acrodermatitis. An important gene associated with Enteropathica is SLC39A4 (Solute Carrier Family 39 Member 4). Affiliated tissues include breast, skin and eye, and related mouse phenotypes are obsolete other and liver/biliary system.

Related Diseases for Enteropathica

About this section

Graphical network of the top 20 diseases related to Enteropathica:



Diseases related to enteropathica

Symptoms & Phenotypes for Enteropathica

About this section

MGI Mouse Phenotypes related to Enteropathica according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.5SLC30A4, SLC39A4
2MP:00053708.5ALB, OTC, PLIN2, SLC39A4
3MP:00053798.3ALB, OTC, PLIN2, SLC30A4, SLC39A4
4MP:00053768.2ALB, OTC, PLIN2, SLC30A4, SLC39A4

Drugs & Therapeutics for Enteropathica

About this section

Drugs for Enteropathica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Zincapproved22317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+

Interventional clinical trials:

idNameStatusNCT IDPhase
1Genetic Study of Severe Zinc DeficienciesCompletedNCT02870166

Search NIH Clinical Center for Enteropathica

Genetic Tests for Enteropathica

About this section

Anatomical Context for Enteropathica

About this section

MalaCards organs/tissues related to Enteropathica:

36
Breast, Skin, Eye, Liver, Colon, Pancreas

Publications for Enteropathica

About this section

Articles related to Enteropathica:

(show top 50)    (show all 361)
idTitleAuthorsYear
1
Sustained Need for High-Dose Zinc Supplementation in Children With Acrodermatitis Enteropathica. (28056538)
2017
2
Acquired acrodermatitis enteropathica as a presenting sign of celiac disease. (27222886)
2016
3
Isoleucine Deficiency in a Neonate Treated for Maple Syrup Urine Disease Masquerading as Acrodermatitis Enteropathica. (27567652)
2016
4
Acrodermatitis enteropathica: A novel mutation of the SLC39A4 gene in a Turkish boy. (26916651)
2016
5
Severe acquired acrodermatitis enteropathica caused by anorexia nervosa. (26661624)
2016
6
An acrodermatitis enteropathica-associated Zn transporter, ZIP4, regulates human epidermal homeostasis. (27940220)
2016
7
Acrodermatitis Enteropathica: A Case Report. (27196457)
2016
8
Bullous acrodermatitis enteropathica: case report of a unique clinical presentation and review of the literature. (25933075)
2015
9
Celiac Disease Presenting With Acquired Acrodermatitis Enteropathica. (26465901)
2015
10
Phrynoderma and acquired acrodermatitis enteropathica in breastfeeding women after bariatric surgery. (26513075)
2015
11
Phrynoderm und erworbene Acrodermatitis enteropathica bei stillenden Frauen nach bariatrischer Chirurgie. (26513074)
2015
12
Acrodermatitis Enteropathica: A Novel SLC39A4 Gene Mutation in a Patient with Normal Zinc Levels. (25780817)
2015
13
Acrodermatitis enteropathica and other nutritional diseases of the folds (intertriginous areas). (26051055)
2015
14
Acrodermatitis enteropathica in an adult. (26244999)
2015
15
Clinical utility gene card for: acrodermatitis enteropathica - update 2015. (26443269)
2015
16
Acrodermatitis enteropathica in an infant with normal zinc levels. (25566908)
2015
17
Genetic causes and genea89nutrient interactions in mammalian zinc deficiencies: acrodermatitis enteropathica and transient neonatal zinc deficiency as examples. (25468189)
2015
18
Identification of a Novel Mutation in the SLC39A4 Gene in a Case of Acrodermatitis Enteropathica. (26351177)
2015
19
One recurrent homozygous mutation of SLC39A4 in a girl with acrodermatitis enteropathica from southwestern China. (24962159)
2014
20
Secondary acrodermatitis enteropathica-like lesions in a child with newly diagnosed coeliac disease. (25540873)
2014
21
Images in clinical medicine. Acquired acrodermatitis enteropathica. (24988559)
2014
22
Development of a plasma zinc concentration cutoff to identify individuals with severe zinc deficiency based on results from adults undergoing experimental severe dietary zinc restriction and individuals with acrodermatitis enteropathica. (24850624)
2014
23
Cow's Milk Protein Allergy Mimicking Acrodermatitis Enteropathica. (24783119)
2014
24
Acrodermatitis enteropathica-like skin lesions in a neonate. (23814231)
2013
25
Acrodermatitis enteropathica in three siblings. (23442482)
2013
26
Transient symptomatic zinc deficiency resembling acrodermatitis enteropathica in a breast-fed premature infant: case report and brief review of the literature. (24442054)
2013
27
Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica. (24015258)
2013
28
Periorificial dermatitis and erosive inguinal plaques in a 57-year-old woman. Acquired zinc deficiency acrodermatitis enteropathica (ADE). (23552816)
2013
29
Images in emergency medicine. Child with diarrhea and rash. Acrodermatitis enteropathica. (24054094)
2013
30
A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity. (22737083)
2012
31
Acrodermatitis enteropathica during adequate enteral nutrition. (22038206)
2012
32
A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene. (23430849)
2012
33
Acrodermatitis enteropathica. (22486149)
2012
34
Clinical utility gene card for: acrodermatitis enteropathica. (22166942)
2012
35
Think zinc deficiency: acquired acrodermatitis enteropathica due to poor diet and common medications. (22911205)
2012
36
Two compound heterozygous novel SLC39A4 mutations in generalized eczematoid acrodermatitis enteropathica. (23228939)
2012
37
Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis. (21424670)
2011
38
Acrodermatitis enteropathica in a 9 month old infant. (21598821)
2011
39
Development of Bullous Acrodermatitis Enteropathica during the Course of Chemotherapy for Acute Lymphocytic Leukemia. (22346269)
2011
40
Acrodermatitis enteropathica: an uncommon differential diagnosis in childhood - first description of a new sequence variant. (21762381)
2011
41
Novel SLC39A4 mutation in acrodermatitis enteropathica. (22082465)
2011
42
Acrodermatitis enteropathica variant with borderline plasma zinc concentrations. (21502834)
2011
43
A case of acrodermatitis enteropathica localized on the hands and feet with a normal serum zinc level. (22028583)
2011
44
Acrodermatitis enteropathica: a novel SLC39A4 gene mutation found in a patient with an early-onset. (21906148)
2011
45
Acrodermatitis enteropathica: a review of 29 Tunisian cases. (20883266)
2010
46
A diagnostic challenge: a case of acrodermatitis enteropathica without hypozincemia and with maternal milk of low zinc level. (20807356)
2010
47
Clinical versus pathologic diagnosis: acrodermatitis enteropathica. (20853573)
2010
48
Symmetrical erythematous and hyperkeratotic plaques. Diagnosis: Acrodermatitis enteropathica (AE). (20653862)
2010
49
One novel homozygous mutation of SLC39A4 gene in a Chinese patient with acrodermatitis enteropathica. (20300938)
2010
50
Acrodermatitis enteropathica with anorexia nervosa. (20649716)
2010

Variations for Enteropathica

About this section

Expression for genes affiliated with Enteropathica

About this section
Search GEO for disease gene expression data for Enteropathica.

Pathways for genes affiliated with Enteropathica

About this section

GO Terms for genes affiliated with Enteropathica

About this section

Cellular components related to Enteropathica according to GeneCards Suite gene sharing:

   (show less)
idNameGO IDTop Affiliating Genes

Biological processes related to Enteropathica according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to zinc ionGO:00100439.3OTC, SLC30A4

Molecular functions related to Enteropathica according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1zinc ion transmembrane transporter activityGO:00053859.5SLC30A4, SLC39A4

Sources for Enteropathica

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet