EATL
MCID: ENT008
MIFTS: 37

Enteropathy-Associated T-Cell Lymphoma (EATL) malady

Rare diseases, Cancer diseases, Gastrointestinal diseases, Blood diseases, Immune diseases categories
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Summaries for Enteropathy-Associated T-Cell Lymphoma

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MalaCards: Enteropathy-Associated T-Cell Lymphoma, also known as high-grade pleomorphic peripheral t-cell lymphoma, is related to celiac disease and refractory celiac disease. An important gene associated with Enteropathy-Associated T-Cell Lymphoma is CD3G (CD3g molecule, gamma (CD3-TCR complex)), and among its related pathways are ERK Signaling and PEDF Induced Signaling. The compounds threonine and prednisolone have been mentioned in the context of this disorder. Affiliated tissues include t cells, colon and brain, and related mouse phenotypes are immune system and hematopoietic system.

Aliases & Classifications for Enteropathy-Associated T-Cell Lymphoma

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43NIH Rare Diseases, 49Orphanet, 62UMLS, 36MESH via Orphanet, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 25ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

49

Aliases & Descriptions:

enteropathy-associated t-cell lymphoma 43 49 62
high-grade pleomorphic peripheral t-cell lymphoma 43
enteropathy-type t-cell lymphoma 49
intestinal t-cell lymphoma 49
eatcl 43
ettl 49
eatl 49


External Ids:

MESH via Orphanet36 D058527
ICD10 via Orphanet26 C84.4
SNOMED-CT via Orphanet59 103686008, 277654008
UMLS via Orphanet63 C0456889
ICD1025 C86.2

Related Diseases for Enteropathy-Associated T-Cell Lymphoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Enteropathy-Associated T-Cell Lymphoma:



Diseases related to enteropathy-associated t-cell lymphoma

Symptoms for Enteropathy-Associated T-Cell Lymphoma

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Drugs & Therapeutics for Enteropathy-Associated T-Cell Lymphoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Enteropathy-Associated T-Cell Lymphoma

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Anatomical Context for Enteropathy-Associated T-Cell Lymphoma

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33MalaCards
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MalaCards organs/tissues related to Enteropathy-Associated T-Cell Lymphoma:

33
T cells, Colon, Brain, Lymph node, Nk cells, B cells, Small intestine

Animal Models for Enteropathy-Associated T-Cell Lymphoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Enteropathy-Associated T-Cell Lymphoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.5CD3G, CCL11, TIA1
2MP:00053978.2CD3G, CCL11, TIA1

Publications for Enteropathy-Associated T-Cell Lymphoma

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52PubMed
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Articles related to Enteropathy-Associated T-Cell Lymphoma:

(show top 50)    (show all 92)
idTitleAuthorsYear
1
Enteropathy-associated T-cell lymphoma diagnosed and followed-up by using double-balloon enteroscopy. (23541443)
2013
2
Classic versus type II enteropathy-associated T-cell lymphoma: diagnostic considerations. (23991736)
2013
3
Enteropathy associated T cell lymphoma in celiac disease: a large retrospective study. (23313469)
2013
4
Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT. (23361910)
2013
5
Brentuximab in the treatment of CD30-positive enteropathy-associated T-cell lymphoma. (23411380)
2013
6
Challenges in the diagnosis of enteropathy-associated T cell lymphoma. (23964351)
2013
7
Clinically undiagnosed enteropathy associated T-cell lymphoma type II presenting with prolonged lower gastrointestinal tract symptoms: report of an autopsy case and review of diagnostic challenges and clinicopathological correlation. (23450273)
2013
8
Type II enteropathy-associated T-cell lymphoma: a multicenter analysis from the Asia Lymphoma Study Group. (22641357)
2012
9
High frequency of fatal haemophagocytic lymphohistiocytosis syndrome in enteropathy-associated T cell lymphoma. (22100722)
2012
10
How I treat enteropathy-associated T-cell lymphoma. (22271451)
2012
11
Enteropathy-associated T-cell lymphoma, lacking MHC class II, with immune-privileged site recurrence, presenting as bilateral ocular vitreous humour involvement - a case report. (22963578)
2012
12
Second line chemotherapy in patients with enteropathy-associated T cell lymphoma: a retrospective single center analysis. (21520002)
2012
13
An unusual enteropathy-associated T-cell lymphoma with MYC translocation arising in a Japanese patient: a case report. (22654438)
2012
14
Supratentorial metastatic enteropathy-associated T-cell lymphoma: A case report and literature review. (23230525)
2012
15
Enteropathy-associated T-cell lymphoma: epidemiology, clinical features, and current treatment strategies. (21912848)
2011
16
Type II enteropathy-associated T-cell lymphoma: a distinct aggressive lymphoma with frequent I^I' T-cell receptor expression. (21921780)
2011
17
A case of enteropathy-associated T-cell lymphoma: diagnosis by flow cytometric immunophenotyping and genome analysis using ascitic fluid. (21604213)
2011
18
Pathological and immunohistological findings and genetic aberrations of intestinal enteropathy-associated T cell lymphoma in Japan. (21323966)
2011
19
Enteropathy-associated T-cell lymphoma: clinical and histological findings from the international peripheral T-cell lymphoma project. (21566094)
2011
20
Phenotypic and genomic analysis of an exceptional case of enteropathy associated T-cell lymphoma. (20226524)
2010
21
Enteropathy-associated T-cell lymphoma: a review on clinical presentation, diagnosis, therapeutic strategies and perspectives. (21050687)
2010
22
Enteropathy associated T-cell lymphoma resulting in restrictive cardiomyopathy and mimicking myocardial infarction. (22767479)
2010
23
Enteropathy associated T-cell lymphoma and its precursor lesions. (20206108)
2010
24
Enteropathy-associated T cell lymphoma of the jejunum associated with colonic lymphocytosis with aberrant phenotype. (20671042)
2010
25
Enteropathy associated T cell lymphoma: common in coeliac disease. (21686880)
2009
26
Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach. (20740143)
2009
27
The phenotype of intraepithelial lymphocytes in Taiwanese enteropathy-associated T-cell lymphoma is distinct from that of the West. (18518903)
2008
28
Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease. (17934841)
2008
29
Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor-CD3 expression in enteropathy-associated T-cell lymphoma. (18815285)
2008
30
Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: retrospective evaluation of single-centre experience. (17470479)
2007
31
Indigo carmine chromoendoscopic appearances of enteropathy-associated T-cell lymphoma during double-balloon endoscopy in a patient with celiac disease. (17614075)
2007
32
Abdominal computed tomography in refractory coeliac disease and enteropathy associated T-cell lymphoma. (17461472)
2007
33
Disappointing outcome of autologous stem cell transplantation for enteropathy-associated T-cell lymphoma. (17531561)
2007
34
Successful treatment of enteropathy-associated T cell lymphoma with autologous stem cell transplant. (16865575)
2006
35
Lymphomatous infiltration of the peripheral nervous system in enteropathy-associated T-cell lymphoma. (15804227)
2005
36
Obstructive jaundice caused by enteropathy-associated T-cell lymphoma in a patient with celiac sprue. (15580407)
2004
37
Enteropathy-associated T-cell lymphoma with initial manifestation in the CNS. (12771280)
2003
38
High-dose therapy supported by autologous stem cell transplantation in patients with enteropathy-associated T-cell lymphoma. (14959866)
2003
39
Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group. (10963198)
2000
40
Refractory coeliac disease: a window between coeliac disease and enteropathy associated T cell lymphoma. (11232488)
2000
41
Enteropathy-associated T-cell lymphoma and its immunocarcinogenic correlates: case report and review of the literature. (9754448)
1998
42
Enteropathy-associated T-cell lymphomas have a cytotoxic T-cell phenotype. (9363445)
1997
43
Enteropathy-associated T-cell lymphoma: a case report with radiographic and computed tomography appearance. (9179268)
1997
44
Molecular analysis of T-cell clonality in ulcerative jejunitis and enteropathy-associated T-cell lymphoma. (9250161)
1997
45
HLA antigen expression in enteropathy associated T cell lymphoma. (8813950)
1996
46
Demonstration of the oligoclonality of an enteropathy associated T-cell lymphoma by monoclonal antibodies and PCR analysis of the T-cell receptor V-beta repertoire on fixed tissue. (8621191)
1996
47
Enteropathy-associated T-cell lymphoma in the West of Ireland: low-frequency of Epstein-Barr virus in these tumors. (8539233)
1995
48
Epstein-Barr virus (EBV) in enteropathy-associated T-cell lymphoma (EATL). (8393922)
1993
49
Low-grade intestinal lymphoma of intraepithelial T lymphocytes with concomitant enteropathy-associated T cell lymphoma: case report suggesting a possible histogenetic relationship. (2789173)
1989
50
Enteropathy-associated T cell lymphoma (malignant histiocytosis of the intestine) is recognized by a monoclonal antibody (HML-1) that defines a membrane molecule on human mucosal lymphocytes. (3260750)
1988

Variations for Enteropathy-Associated T-Cell Lymphoma

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Expression for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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Pathways for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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50PathCards, 53QIAGEN, 30KEGG, 38NCBI BioSystems Database
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Compounds for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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45Novoseek, 29IUPHAR, 11DrugBank
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Compounds related to Enteropathy-Associated T-Cell Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1threonine459.1CCL11, TIA1
2prednisolone45 29 1110.8CCL11, TIA1

GO Terms for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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Products for genes affiliated with Enteropathy-Associated T-Cell Lymphoma

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Sources for Enteropathy-Associated T-Cell Lymphoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet