Aliases & Classifications for Enthesopathy

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Summaries for Enthesopathy

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Wikipedia:69 In medicine, an enthesopathy refers to a disorder involving the attachment of a tendon or ligament to a... more...

MalaCards based summary: Enthesopathy, also known as rheumatic diseases, is related to hyperostosis and diffuse idiopathic skeletal hyperostosis, and has symptoms including metatarsalgia, tenalgia and tendon discomfort. An important gene associated with Enthesopathy is PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked). Affiliated tissues include bone and skin, and related mouse phenotype growth/size/body region.

Related Diseases for Enthesopathy

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Diseases related to Enthesopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1hyperostosis26.0DMP1, FGF23, H19, MEFV, MRAP, PHB2
2diffuse idiopathic skeletal hyperostosis10.6
3epicondylitis10.6
4jacobsen syndrome10.4FGF23, PHEX
5familial wilms tumor 210.3FGF23, PHEX
6peroxisome biogenesis disorder 2a10.3FGF23, PHEX
7atelosteogenesis10.3FGF23, PHEX
8arthropathy10.2
9prostate cancer, hereditary, x-linked 210.2FGF23, PHEX
10arthritis10.2
11colorectal cancer, hereditary nonpolyposis, type 410.2DMP1, FGF23
12spondylitis10.2
13psoriasis10.2
14louse-borne relapsing fever10.2MRAP, PHB2
15nephrosclerosis10.2MEFV, MRAP
16osteoarthritis10.2
17acute diffuse nephritis10.2MRAP, PHB2
18loeys-dietz syndrome10.1FGF23, PHEX
19glanders10.1MRAP, PHB2
20psoriatic arthritis10.1
21spondyloarthropathy10.1
22astrakhan spotted fever10.1FGF23, PHEX
23benign vaginal carcinosarcoma10.0MRAP, PHB2
24hypophosphatemia10.0
25tendinitis10.0
26patellar tendinitis10.0
27heel spur10.0
28periarthritis10.0
29tendinopathy10.0
30bone deterioration disease10.0FGF23, PHEX
31onychotrichodysplasia and neutropenia9.9DMP1, FGF23, PHEX
32spastic ataxia9.9DMP1, FGF23, PHEX
33sensory peripheral neuropathy9.9DMP1, FGF23, PHEX
34brugada syndrome9.9DMP1, FGF23, PHEX
35commensal bacterial infectious disease9.9DMP1, FGF23, PHEX
36tuberous sclerosis-19.9DMP1, FGF23, PHEX
37synovitis9.9
38fasciitis9.9
39plantar fasciitis9.9
40spondylarthropathy9.9
41xanthomatosis9.9MRAP, PHB2
42leukodystrophy9.9DMP1, FGF23, PHEX
43achilles bursitis9.9
44protein-losing enteropathy9.9DMP1, FGF23, PHEX
45renal artery obstruction9.8PHB2, SERPINI2
46status epilepticus9.8FGF23, PHEX
47leprosy9.7
48acne9.7
49primary biliary cirrhosis9.7
50gout9.7

Comorbidity relations with Enthesopathy via Phenotypic Disease Network (PDN):


Hypertension, EssentialAcute Cystitis

Graphical network of the top 20 diseases related to Enthesopathy:



Diseases related to enthesopathy

Symptoms for Enthesopathy

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UMLS symptoms related to Enthesopathy:


metatarsalgia, tenalgia, tendon discomfort

Drugs & Therapeutics for Enthesopathy

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Drugs for Enthesopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LidocainePhase 2, Phase 3, Phase 11168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
2
ThalidomidePhase 3106050-35-15426
Synonyms:
( inverted question mark)-Thalidomide
(+)-Thalidomide
(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide
(+-)-Thalidomide
(+/-)-THALIDOMIDE
(?)-Thalidomide
(±)-N-(2,6-dioxo-3-piperidyl)phthalimide
(±)-thalidomide
.alpha.-(N-Phthalimido)glutarimide
.alpha.-N-Phthalylglutaramide
.alpha.-Phthalimidoglutarimide
1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline
14088-68-7
2,6-Dioxo-3-phthalimidopiperidine
2,6-dioxo-3-phthalimidopiperidine
3-Phthalimidoglutarimide
50-35-1
731-40-8
AB00052362
AC-917
AC1L1KBZ
AC1Q6FJA
AI3-50606
Algosediv
Asidon 3
Asmadion
Asmaval
BPBio1_000159
BRD-A93255169-001-06-9
BRN 0030233
BSPBio_000143
BSPBio_001156
BSPBio_003330
Bio1_000387
Bio1_000876
Bio1_001365
Bio2_000418
Bio2_000898
Bonbrain
Bonbrrin
C07910
C13H10N2O4
CCRIS 8148
CHEBI:105028
CHEMBL468
CID5426
CPD000058524
Calmore
Calmorex
Celgene Brand of Thalidomide
Contergan
Corronarobetin
D00754
D013792
DB01041
Distaval
Distaxal
Distoval
DivK1c_000051
E-217
EINECS 200-031-1
ENMD 0995
EU-0101224
Ectiluran
Enterosediv
Gastrinide
Glupan
Glutanon
Grippex
HMS1362J17
HMS1568H05
HMS1792J17
HMS1922E12
HMS1990J17
HMS2090O05
HMS2093G15
HMS500C13
HSDB 3586
Hippuzon
I06-0197
IDI1_000051
IDI1_002173
IN1061
Imida-Lab
Imida-lab
Imidan
Imidan (peyta)
Imidene
Isomin
K 17
K-17
KBio1_000051
KBio2_000496
KBio2_002322
KBio2_003064
KBio2_004890
KBio2_005632
KBio2_007458
KBio3_000911
KBio3_000912
KBio3_002550
KBio3_002802
KBioGR_000496
KBioGR_001474
KBioGR_002322
KBioSS_000496
KBioSS_002324
Kedavon
Kevadon
LS-109463
LS-140
Lopac0_001224
Lulamin
MLS000069353
MolPort-003-665-582
N-(2,6-Dioxo-3-piperidyl)phthalimide
N-(2,6-dioxo-3-piperidyl)phthalimide
N-Phthalimidoglutamic acid imide
N-Phthaloylglutamimide
N-Phthalyl-glutaminsaeure-imid
N-Phthalyl-glutaminsaeure-imid [German]
N-Phthalylglutamic acid imide
NCGC00015989-03
NCGC00015989-13
NCGC00024708-02
 
NCGC00024708-03
NCGC00024708-04
NCGC00024708-05
NCGC00024708-06
NCGC00024708-07
NCGC00024708-08
NCGC00024708-09
NCI60_023904
NCIOpen2_003188
NINDS_000051
NSC 527179
NSC-66847
NSC527179
NSC66847
NSC91729
NSC91730
Neaufatin
Neo
Neosedyn
Neosydyn
Nerosedyn
Neufatin
Neurodyn
Neurosedin
Neurosedym
Neurosedyn
Nevrodyn
Nibrol
Noctosediv
Noxodyn
Pangul
Pantosediv
Poly-Giron
Polygripan
Predni-Sediv
Prestwick0_000192
Prestwick1_000192
Prestwick2_000192
Prestwick3_000192
Prestwick_463
Pro-Bam M
Pro-ban M
Profarmil
Psycholiquid
Psychotablets
Quetimid
Quietoplex
S1193_Selleck
SAM002564245
SMR000058524
SPBio_000893
SPBio_002064
SPECTRUM1503607
ST51039042
Sandormin
Sedalis
Sedalis sedi-lab
Sedimide
Sedin
Sedisperil
Sedoval
Shin-naito S
Shinnibrol
Sleepan
Slipro
Softenil
Softenon
Spectrum2_000707
Spectrum3_001715
Spectrum4_001087
Spectrum5_001791
Synovir
T144_SIGMA
T150_SIGMA
T151_SIGMA
THALIDOMIDE (AIDS INITIATIVE)
Talargan
Talidomida
Talidomida [INN-Spanish]
Talidomide
Talidomide [DCIT]
Talimol
Talismol
Talizer
Telagan
Telargan
Telargean
Tensival
Thaled
Thaled (TN)
Thalidomide
Thalidomide (+ and -)
Thalidomide (JAN/USP/INN)
Thalidomide (soluble form)
Thalidomide Celgene
Thalidomide Pharmion
Thalidomide [USAN:INN:BAN]
Thalidomidum
Thalidomidum [INN-Latin]
Thalidomine USP26
Thalin
Thalinette
Thalomid
Thalomid (TM)
Thalomid (TN)
Thalomid, Thalidomide
Thalomide
Theophilcholine
UNII-4Z8R6ORS6L
UPCMLD-DP139
UPCMLD-DP139:001
Valgis
Valgraine
WLN: T56 BVNVJ C- DT6VMVTJ
WLN: T56 BVNVJ C- DT6VMVTJ -D
WLN: T56 BVNVJ C- DT6VMVTJ -L
Yodomin
alpha-(N-Phthalimido)glutarimide
alpha-N-Phthalylglutaramide
alpha-Phthalimidoglutarimide
alpha-phthalimidoglutarimide
cMAP_000022
thalidomide
α-(N-phthalimido)glutarimide
α-N-phthalylglutaramide
α-phthalimidoglutarimide
3
ApremilastPhase 360608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
Apremilastum
Aprémilast
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
4
Iodine5167553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
5cadexomer iodine484

Interventional clinical trials:

idNameStatusNCT IDPhase
1Treatment for Achilles TendinopathyActive, not recruitingNCT00835939Phase 2, Phase 3
2Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis (PsA)Active, not recruitingNCT01307423Phase 3
3Effectiveness of Dextrose Injection for Osgood-Schlatter DiseaseCompletedNCT01300754Phase 1, Phase 2
4Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the ShoulderCompletedNCT02677103
5Distal Erosions and Nail PsoriasisRecruitingNCT02813720
6Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich PlasmaRecruitingNCT01406821
7Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) InjectionsRecruitingNCT01200875

Search NIH Clinical Center for Enthesopathy


Cochrane evidence based reviews: rheumatic diseases

Genetic Tests for Enthesopathy

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Anatomical Context for Enthesopathy

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MalaCards organs/tissues related to Enthesopathy:

34
Bone, Skin

Animal Models for Enthesopathy or affiliated genes

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MGI Mouse Phenotypes related to Enthesopathy:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053787.5DMP1, FGF23, MEFV, PHB2, PHEX, SERPINI2

Publications for Enthesopathy

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Articles related to Enthesopathy:

(show top 50)    (show all 143)
idTitleAuthorsYear
1
Factors associated with operative treatment of enthesopathy of the extensor carpi radialis brevis origin. (26995457)
2016
2
A Meta-Analysis of the Effect of Corticosteroid Injection for Enthesopathy of the Extensor Carpi Radialis Brevis Origin. (27546443)
2016
3
Investigation of Enthesopathy with Ultrasonography and Comparison with Skin Findings in Asymptomatic Psoriatic Patients. (27028326)
2016
4
Pelvic enthesopathy on CT is significantly more prevalent in patients with diffuse idiopathic skeletal hyperostosis (DISH) compared with matched control patients. (26686367)
2015
5
Conventional Therapy in Adults With XLH Improves Dental Manifestations, But Not Enthesopathy. (26439151)
2015
6
Enthesopathy of the pectoralis major tendon mimicking osteoid osteoma. A case report with an unfortunate series of events. (26605199)
2015
7
Enthesopathy of the lateral cord of the plantar fascia. (25154957)
2014
8
The enthesopathy of celiac patients: effects of gluten-free diet. (24567238)
2014
9
The use of the HiSPECT bone scan in canine flexor enthesopathy and coronoid pathology. (23375664)
2013
10
Transcatheter arterial embolization using imipenem/cilastatin sodium for tendinopathy and enthesopathy refractory to nonsurgical management. (23707086)
2013
11
MAGNETIC RESONANCE IMAGING OF PRIMARY AND CONCOMITANT FLEXOR ENTHESOPATHY IN THE CANINE ELBOW. (24033814)
2013
12
Enthesopathy and desmitis of the medial collateral ligament of the cubital joint in 4 horses. (23547681)
2013
13
COMPUTED TOMOGRAPHY OF CANINE ELBOW JOINTS AFFECTED BY PRIMARY AND CONCOMITANT FLEXOR ENTHESOPATHY. (24033837)
2013
14
Assessment of enthesopathy in patients with fibromyalgia by using new sonographic enthesitis index. (24217664)
2013
15
Arthroscopic features of primary and concomitant flexor enthesopathy in the canine elbow. (23708890)
2013
16
Primary and concomitant flexor enthesopathy of the canine elbow. (23801308)
2013
17
Ultrasonographic assessment of nail in psoriatic disease shows a link between onychopathy and distal interphalangeal joint extensor tendon enthesopathy. (23128597)
2012
18
Bone scan in enthesopathy involving tendo Achilles. (22228344)
2012
19
Lipopolysaccharide treatment suppresses spontaneously developing ankylosing enthesopathy in B10.BR male mice: the potential role of interleukin-10. (22721554)
2012
20
Prevalence of subclinical enthesopathy in patients with spondyloarthropathy: an ultrasound study. (21169854)
2011
21
Preliminary evidence that subclinical enthesopathy may predict psoriatic arthritis in patients with psoriasis. (22134799)
2011
22
Images in rheumatology. Heel enthesopathy of diffuse idiopathic skeletal hyperostosis resembling enthesitis of spondyloarthritis. (20040638)
2010
23
Ultrasound of enthesopathy in rheumatic diseases. (19002749)
2009
24
Enthesopathy of the bicipital tuberosity of the radius causing painful forearm rotation. (19046644)
2009
25
Commensal intestinal bacterial strains trigger ankylosing enthesopathy of the ankle in inbred B10.BR (H-2(k)) male mice. (18840492)
2008
26
Increased enthesopathy among BehAset's syndrome patients with acne and arthritis: an ultrasonography study. (18438817)
2008
27
Varied presentations of enthesopathy. (17350676)
2007
28
Therapies for psoriatic enthesopathy. A systematic review. (16724370)
2006
29
Achilles tendon enthesopathy in ochronosis. (16534167)
2006
30
Ultrasonography in the early diagnosis of psoriasis-associated enthesopathy. (16440579)
2005
31
High prevalence of symptomatic enthesopathy of the shoulder in ankylosing spondylitis: deltoid origin involvement constitutes a hallmark of disease. (15478149)
2004
32
Enthesopathy: clinical recognition and significance. (11396326)
2001
33
A rare case of enthesopathy of the bicipital tuberositas of the radius. (11110146)
2000
34
Grouped caging predisposes male mice to ankylosing enthesopathy. (8882137)
1996
35
Enthesopathy in leprosy. (8782134)
1996
36
The absence of human beta 2-microglobulin increases the occurrence of ankylosing enthesopathy in HLA-B27 transgenic mice. (8835498)
1996
37
Solitary caging protects mice from ankylosing enthesopathy. (8835499)
1996
38
Selective IgA deficiency in seronegative enthesopathy and arthropathy syndrome. (8574636)
1995
39
A rare enthesopathy in psoriatic oligoarthritis. (8073846)
1994
40
Enthesopathy of the patellar tendon insertion associated with isotretinoin therapy. (8441038)
1993
41
Retro runner with ischial tuberosity enthesopathy. (8467344)
1993
42
The significance of enthesopathy as a skeletal phenomenon. (8403585)
1993
43
Low frequency of axial involvement in Caucasian pediatric patients with seronegative enthesopathy and arthropathy syndrome after 5 years of disease. (1578464)
1992
44
"Tumoral" enthesopathy: a juxtacortical osteosarcoma simulation. (1765994)
1991
45
Tc-99m MDP bone imaging in inflammatory enthesopathy. (2311317)
1990
46
From ankylosing spondylitis to Forestier's disease: ossifying enthesopathy, a unifying concept. (2117661)
1990
47
Axial involvement in the seronegative enthesopathy and arthropathy syndrome and its progression to ankylosing spondylitis. (2526221)
1989
48
Enthesopathy of the hip joint. (3924467)
1985
49
Enthesopathy of the heels in juvenile onset seronegative B-27 positive spondyloarthropathy. (3875722)
1985
50
HLA-B27-associated spondyloarthritis and enthesopathy in childhood: clinical, pathologic, and radiographic observations in 58 patients. (6977633)
1982

Variations for Enthesopathy

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Expression for genes affiliated with Enthesopathy

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Search GEO for disease gene expression data for Enthesopathy.

Pathways for genes affiliated with Enthesopathy

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GO Terms for genes affiliated with Enthesopathy

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Sources for Enthesopathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet