EGE
MCID: ESN005
MIFTS: 50

Eosinophilic Gastroenteritis (EGE) malady

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Eosinophilic Gastroenteritis

Aliases & Descriptions for Eosinophilic Gastroenteritis:

Name: Eosinophilic Gastroenteritis 12 56 52 14 69
Eosinophilic Gastroenterocolitis 56
Eosinophilic Enteropathy 69
Eosinophilic Enteritis 56
Ege 56

Characteristics:

Orphanet epidemiological data:

56
eosinophilic gastroenteritis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:



External Ids:

Disease Ontology 12 DOID:4031
ICD9CM 35 558.41
MeSH 42 C535952
NCIt 47 C35330
Orphanet 56 ORPHA2070
UMLS via Orphanet 70 C1262481
ICD10 via Orphanet 34 K52.8
MESH via Orphanet 43 C535952
UMLS 69 C1262481

Summaries for Eosinophilic Gastroenteritis

MalaCards based summary : Eosinophilic Gastroenteritis, also known as eosinophilic gastroenterocolitis, is related to eosinophilic enteropathy and gastroenteritis, and has symptoms including edema, abdominal pain and vomiting. An important gene associated with Eosinophilic Gastroenteritis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. The drugs Budesonide and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and t cells.

Wikipedia : 71 Eosinophilic gastroenteritis (EG) is a rare and heterogeneous condition characterized by patchy or... more...

Related Diseases for Eosinophilic Gastroenteritis

Diseases related to Eosinophilic Gastroenteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
id Related Disease Score Top Affiliating Genes
1 eosinophilic enteropathy 11.2
2 gastroenteritis 10.9
3 exercise-induced anaphylaxis 10.8
4 kahrizi syndrome 10.2 IL3 IL5
5 peptidic growth factors deficiency 10.2 CCL11 IL5
6 natural killer cell leukemia 10.2 CCL11 IL5
7 thelaziasis 10.2 CCL11 IL5
8 lymphoblastic leukemia 10.2 CCL11 IL5
9 spastic diplegia 10.2 CCL11 IL5
10 restrictive cardiomyopathy 10.2 IL5 RNASE3
11 duodenitis 10.2
12 marasmus 10.2 IL5 RNASE3
13 renal hypertension 10.2 IL5 RNASE3
14 disordered steroidogenesis due to cytochrome p450 oxidoreductase 10.2 CCL11 IL5
15 lens-induced iridocyclitis 10.2 IL5 RNASE3
16 brown shrimp allergy 10.2 IL5 RNASE3
17 cutaneous fibrous histiocytoma 10.2 CCL11 IL5
18 esophagitis 10.2
19 luminal breast carcinoma 10.2 IL5 RNASE3
20 benign meningioma 10.2 IL5 RNASE3
21 infectious anterior uveitis 10.1 IL5 RNASE3
22 pancreatitis 10.1
23 anterior dislocation of lens 10.1 CCL11 RNASE3
24 bile duct signet ring cell carcinoma 10.1 IL5 RNASE3
25 small intestine lymphoma 10.1 IL5 RNASE3
26 orbit alveolar rhabdomyosarcoma 10.1 IL5 RNASE3
27 endotheliitis 10.1
28 astrocytoma 10.1 IL5 RNASE3
29 protein-losing enteropathy 10.1
30 wilkes stevenson syndrome 10.1 IL5 RNASE3
31 dissociated nystagmus 10.1 EPX IL5
32 amelogenesis imperfecta 1j 10.1 EPX RNASE3
33 mansonelliasis 10.1 ALB IL5
34 actinic keratosis 10.1 IL5 RNASE3
35 appendix carcinoid tumor 10.1 EPX RNASE3
36 lymphocytic gastritis 10.1 CCL11 IL3 IL5
37 conjunctival concretion 10.1 CCL11 IL5
38 cytokine receptor deficiency 10.1 CSF2 IL3
39 febrile seizures, familial, 2 10.1 CSF2 IL3
40 chemical colitis 10.0 EPX RNASE3
41 mental retardation, autosomal dominant 37 10.0 CSF2 IL3
42 scalp dermatosis 10.0 EPX RNASE3
43 multiple epiphyseal dysplasia due to collagen 9 anomaly 10.0 IL3 IL5 RNASE3
44 scleroderma, familial progressive 10.0 CSF2 IL3
45 lactose intolerance 10.0 CSF2 IL5
46 latent syphilis 10.0 CCL11 IL5 RNASE3
47 cerebral primitive neuroectodermal tumor 10.0 CCL11 IL5 RNASE3
48 apricot allergy 10.0 CCL11 IL5 RNASE3
49 trachea leiomyoma 10.0 CCL11 IL5 RNASE3
50 visceral steatosis 10.0 CCL11 IL5 RNASE3

Graphical network of the top 20 diseases related to Eosinophilic Gastroenteritis:



Diseases related to Eosinophilic Gastroenteritis

Symptoms & Phenotypes for Eosinophilic Gastroenteritis

Human phenotypes related to Eosinophilic Gastroenteritis:

56 32 (show all 19)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 edema 56 32 Occasional (29-5%) HP:0000969
2 abdominal pain 56 32 Frequent (79-30%) HP:0002027
3 vomiting 56 32 Frequent (79-30%) HP:0002013
4 dysphagia 56 32 Frequent (79-30%) HP:0002015
5 ascites 56 32 Occasional (29-5%) HP:0001541
6 anemia 56 32 Frequent (79-30%) HP:0001903
7 weight loss 56 32 Occasional (29-5%) HP:0001824
8 asthma 56 32 Occasional (29-5%) HP:0002099
9 leukocytosis 56 32 Frequent (79-30%) HP:0001974
10 hematochezia 56 32 Occasional (29-5%) HP:0002573
11 elevated c-reactive protein level 56 32 Frequent (79-30%) HP:0011227
12 elevated erythrocyte sedimentation rate 56 32 Occasional (29-5%) HP:0003565
13 hypoalbuminemia 56 32 Frequent (79-30%) HP:0003073
14 protein-losing enteropathy 56 32 Occasional (29-5%) HP:0002243
15 steatorrhea 56 32 Frequent (79-30%) HP:0002570
16 allergic rhinitis 56 32 Frequent (79-30%) HP:0003193
17 atopic dermatitis 56 32 Occasional (29-5%) HP:0001047
18 diarrhea 56 Frequent (79-30%)
19 malabsorption 56 Frequent (79-30%)

Drugs & Therapeutics for Eosinophilic Gastroenteritis

Drugs for Eosinophilic Gastroenteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Budesonide Approved Phase 4,Phase 3,Phase 2 51333-22-3 63006 5281004
2
Lansoprazole Approved, Investigational Phase 4,Phase 2,Phase 1 103577-45-3 3883
3
Menthol Approved Phase 4 2216-51-5 16666
4 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
5 Cromolyn Sodium Phase 4
6 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
8 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Autonomic Agents Phase 4,Phase 3,Phase 2
10 Bronchodilator Agents Phase 4,Phase 3,Phase 2
11 Dermatologic Agents Phase 4,Phase 3,Phase 2
12
Fluticasone Phase 4,Phase 3,Phase 2 90566-53-3, 80474-14-2 62924 22833648
13 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
14 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
15 Hormones Phase 4,Phase 3,Phase 2,Phase 1
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
17 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
18 Antacids Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
19 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
20
Dexlansoprazole Phase 4,Phase 2,Phase 1 138530-94-6, 103577-45-3 9578005
21 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
22
Proton pump inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
23 Olive Nutraceutical Phase 4
24 Soy Bean Nutraceutical Phase 4,Phase 2,Phase 3,Early Phase 1
25
Montelukast Approved Phase 3,Phase 1 158966-92-8 5281040
26
Esomeprazole Approved, Investigational Phase 2, Phase 3 161796-78-7, 119141-88-7 4594 9579578
27 Leukotriene Antagonists Phase 3,Phase 1
28 Bone Density Conservation Agents Phase 3
29 Calcium, Dietary Phase 3
30
Omalizumab Approved, Investigational Phase 2,Phase 1 242138-07-4
31
Infliximab Approved Phase 2 170277-31-3
32
Losartan Approved Phase 2 114798-26-4 3961
33
Bethanechol Approved Phase 2 674-38-4 2370
34 Antibodies Phase 2,Phase 1
35 Antibodies, Monoclonal Phase 2,Phase 1
36 Immunoglobulins Phase 2,Phase 1
37 Indoleacetic Acids Phase 2
38 Antirheumatic Agents Phase 2
39 interferons Phase 1, Phase 2
40 Analgesics Phase 2
41 Analgesics, Non-Narcotic Phase 2
42 Anti-Inflammatory Agents, Non-Steroidal Phase 2
43 Mesalamine Phase 2 89-57-6
44 Cholinergic Agents Phase 2
45 Neurotransmitter Agents Phase 2
46 Pharmaceutical Solutions Phase 2
47
Angiotensin II Phase 2 68521-88-0, 11128-99-7 65143 172198
48 Angiotensin II Type 1 Receptor Blockers Phase 2
49 Angiotensin Receptor Antagonists Phase 2
50 Angiotensinogen Phase 2

Interventional clinical trials:

(show top 50) (show all 116)
id Name Status NCT ID Phase
1 Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis Unknown status NCT02371941 Phase 4
2 Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis Unknown status NCT01846962 Phase 4
3 The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors Terminated NCT01404832 Phase 4
4 Open-Label Extension Study of Reslizumab in Pediatric Subjects With Eosinophilic Esophagitis Completed NCT00635089 Phase 3
5 Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years Completed NCT00538434 Phase 2, Phase 3
6 Budesonide Orodispersible Tablet vs. Placebo in Active Eosinophilic Esophagitis Completed NCT02434029 Phase 3
7 A Study Comparing Swallowed Flovent and Placebo in Patients With Eosinophilic Disorders Completed NCT00266578 Phase 3
8 The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis Completed NCT00728481 Phase 2, Phase 3
9 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3
10 Maintenance of Remission With Budesonide Orodispersible Tablets vs. Placebo in Eosinophilic Esophagitis Recruiting NCT02493335 Phase 3
11 A Placebo- Controlled Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved Recruiting NCT02605837 Phase 3
12 An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) Recruiting NCT02736409 Phase 3
13 Eosinophilic Esophagitis (EoE) Intervention Trial-Randomized 1 Food Elimination vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids Recruiting NCT02610816 Phase 2, Phase 3
14 SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study Recruiting NCT02778867 Phase 2, Phase 3
15 Eosinophilic Esophagitis Treatment: Montelukast vs Fluticasone Active, not recruiting NCT01702701 Phase 3
16 Safety and Efficacy of Three Doses of Oral Fluticasone Propionate in Adults With Eosinophilic Esophagitis Not yet recruiting NCT02873468 Phase 2, Phase 3
17 A Study of Flovent in Patients With Eosinophilic Esophagitis Completed NCT00426283 Phase 2
18 Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis Completed NCT00762073 Phase 2
19 Budesonide for Eosinophilic Esophagitis Completed NCT00271349 Phase 2
20 Topical Steroid Treatment for Eosinophilic Esophagitis Completed NCT00275561 Phase 2
21 Omalizumab to Treat Eosinophilic Gastroenteritis Completed NCT00084097 Phase 2
22 Use of Topical Budesonide in the Treatment of Eosinophilic Esophagitis Completed NCT00638456 Phase 2
23 Proof of Concept Study of OC000459 in Eosinophilic Esophagitis Completed NCT01056783 Phase 2
24 Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis Completed NCT02098473 Phase 2
25 Budesonide Effervescent Tablets vs. Viscous Budesonide Suspension vs. Placebo in Eosinophilic Esophagitis Completed NCT02280616 Phase 2
26 Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic Esophagitis Completed NCT01386112 Phase 1, Phase 2
27 Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis Completed NCT01022970 Phase 2
28 A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab Completed NCT00123630 Phase 2
29 Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis Completed NCT00123656 Phase 2
30 Off Label Use of Infliximab in Adult Patients With Severe Eosinophilic Esophagitis Completed NCT00523354 Phase 2
31 OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension Completed NCT01642212 Phase 2
32 An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Oesophagitis In Adult Patients Completed NCT00274703 Phase 2
33 Intravenous Mepolizumab In Children With Eosinophilic Esophagitis Completed NCT00358449 Phase 2
34 Anti-Interleukin-5 Antibody to Treat Hypereosinophilic Syndrome Completed NCT00017862 Phase 2
35 Anti-Interleukin-5 (IL-5) Study for Hypereosinophilic Syndrome Completed NCT00266565 Phase 1, Phase 2
36 Mesalazine Treatment in IBS (The MIBS Study) Completed NCT01699438 Phase 2
37 Eosinophilic Esophagitis Clinical Therapy Comparison Trial Recruiting NCT01821898 Phase 2
38 An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE) Recruiting NCT03029091 Phase 2
39 Milk Patch for Eosinophilic Esophagitis Active, not recruiting NCT02579876 Phase 2
40 Study of Dupilumab in Adult Patients With Active Eosinophilic Esophagitis (EoE) Active, not recruiting NCT02379052 Phase 2
41 Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD Active, not recruiting NCT01808196 Phase 2
42 Mometasone-furoate for Treatment of Eosinophilic Esophagitis - a Randomized Placebo Controlled Study. Enrolling by invitation NCT02113267 Phase 2
43 Bethanechol for Eosinophilic Esophagitis Terminated NCT02058537 Phase 2
44 Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Withdrawn NCT01479231 Phase 1, Phase 2
45 Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD Withdrawn NCT01025739 Phase 2
46 Observational Field Study of Acute Esophageal Food Bolus Impaction by Mean Esophageal Manometry and 24h-pH-monitoring Unknown status NCT01447823 Phase 1
47 Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients Completed NCT01641913 Phase 1
48 Identifying Responders to Xolair (Omalizumab) Using Eosinophilic Esophagitis as a Disease Model Completed NCT01040598 Phase 1
49 Trial of Montelukast in Eosinophilic Esophagitis Completed NCT00511316 Phase 1
50 A Randomized Double Blind Placebo Controlled Study of the Effect of Swallowed Beclomethasone Dipropionate on Inflammatory Markers in Adult Patients With Eosinophilic Esophagitis Completed NCT01016223 Phase 1

Search NIH Clinical Center for Eosinophilic Gastroenteritis

Genetic Tests for Eosinophilic Gastroenteritis

Anatomical Context for Eosinophilic Gastroenteritis

MalaCards organs/tissues related to Eosinophilic Gastroenteritis:

39
Colon, Small Intestine, T Cells, Liver, Thyroid, Pancreas, Pituitary

Publications for Eosinophilic Gastroenteritis

Articles related to Eosinophilic Gastroenteritis:

(show top 50) (show all 380)
id Title Authors Year
1
Post-partum eosinophilic gastroenteritis: A case report. ( 28081983 )
2017
2
Eosinophilic gastroenteritis: three clinical cases with different presentations. ( 28063615 )
2017
3
Lack of Knowledge and Low Readiness for Healthcare Transition in Eosinophilic Esophagitis and Eosinophilic Gastroenteritis. ( 27657884 )
2016
4
Eosinophilic gastroenteritis: A state-of-the-art review. ( 27253425 )
2016
5
Eosinophilic gastroenteritis in a patient with Bruton's tyrosine kinase deficiency. ( 26840762 )
2016
6
Eosinophilic gastroenteritis: Approach to diagnosis and management. ( 27867684 )
2016
7
Eosinophilic gastroenteritis: a challenge to diagnose and treat. ( 27613263 )
2016
8
Eosinophilic gastroenteritis in an 18-year-old male with prolonged nephrotic syndrome. ( 28018451 )
2016
9
Eosinophilic gastroenteritis in a woman with multiple sclerosis on dimethyl fumarate. ( 27466473 )
2016
10
Eosinophilic Gastroenteritis: An Underdiagnosed Condition. ( 27234270 )
2016
11
Eosinophilic Gastroenteritis as a Rare Cause of Recurrent Epigastric Pain. ( 27274524 )
2016
12
Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels. ( 26948075 )
2016
13
Severe eosinophilic gastroenteritis. ( 26802190 )
2016
14
A Case of Eosinophilic Gastroenteritis Forming a Rigid Chamber Mimicking Giant Duodenal Ulcer on Computed Tomography Imaging. ( 27086704 )
2016
15
Severe Eosinophilic Gastroenteritis in a Crohn's Disease Patient Treated With Infliximab and Adalimumab. ( 27018120 )
2016
16
A Case of Proton Pump Inhibitor-Resistant Multiple Gastric Ulcers Caused by Eosinophilic Gastroenteritis. ( 26272422 )
2015
17
Eosinophilic gastroenteritis due to rhus ingestion presenting with gastrointestinal hemorrhage. ( 25844348 )
2015
18
Differences in Features and Course of Mucosal Type Eosinophilic Gastroenteritis between Korean Infants and Children. ( 26240491 )
2015
19
The management of eosinophilic gastroenteritis. ( 26027839 )
2015
20
Perforated duodenal ulcer: An unusual manifestation of allergic eosinophilic gastroenteritis. ( 26640348 )
2015
21
Systematic Review: The Efficacy of Dietary Treatment for Inducing Disease Remission in Eosinophilic Gastroenteritis. ( 25699593 )
2015
22
A Case of Eosinophilic Gastroenteritis with Ascites. ( 26819619 )
2015
23
Eosinophilic gastroenteritis as an unusual manifestation of multiple mesenteric lymph node enlargements and recurrent diarrheas. ( 26006212 )
2015
24
A case of a teenage boy with eosinophilic gastroenteritis with esophageal involvement developing a hemorrhagic duodenal ulcer. ( 26037474 )
2015
25
Eosinophilic gastroenteritis: Clinical profiles and treatment outcomes, a retrospective study of 18 adult patients in a Singapore Tertiary Hospital. ( 26358020 )
2015
26
Eosinophilic Gastroenteritis: Case Report and Review in Search for Diagnostic Key Points. ( 26075112 )
2015
27
Allergic Bronchopulmonary Aspergillosis Associated With Eosinophilic Gastroenteritis. ( 26727774 )
2015
28
Proton pump inhibitor treatment decreased duodenal and esophageal eosinophilia in a case of eosinophilic gastroenteritis. ( 26344087 )
2015
29
Eosinophilic gastroenteritis associated with eosinophilic cystitis: Computed tomography and magnetic resonance imaging findings. ( 25780317 )
2015
30
Eosinophilic gastroenteritis and bowel obstruction. Can surgery be avoided? ( 25733047 )
2015
31
An Atypical Case of Eosinophilic Gastroenteritis Presenting as Hypovolemic Shock. ( 26078733 )
2015
32
Eosinophilic gastroenteritis due to egg allergy presenting as acute pancreatitis. ( 25668683 )
2015
33
Obstructive eosinophilic gastroenteritis in a patient with rheumatoid arthritis. ( 26264946 )
2015
34
Eosinophilic gastroenteritis after allogeneic bone marrow transplantation. ( 25913480 )
2015
35
Milk-sensitive eosinophilic gastroenteritis in a 2-month-old boy. ( 26272958 )
2015
36
Eosinophilic gastroenteritis mimicking as a malignant gastric ulcer with lymphadenopathy as shown by computed tomography and endoscopic ultrasound. ( 25789292 )
2015
37
Eosinophilic Gastroenteritis with Ascites in a Child. ( 26388635 )
2015
38
Eosinophilic Gastroenteritis and Colitis: a Comprehensive Review. ( 26054822 )
2015
39
Clinical Manifestations and Treatment Outcomes of Eosinophilic Gastroenteritis in Children. ( 26770900 )
2015
40
Clinical characteristics, treatment outcomes, and resource utilization in children and adults with eosinophilic gastroenteritis. ( 25547198 )
2015
41
Eosinophilic gastroenteritis cured with Helicobacter pylori eradication: case report and review of literature. ( 24650300 )
2014
42
Eosinophilic gastroenteritis complicated with Helicobacter pylori infection unresponsive to eradication therapy. ( 25224188 )
2014
43
Eosinophilic gastroenteritis treated with a multiple-food elimination diet. ( 24809376 )
2014
44
Eosinophilic gastroenteritis with involvement of the urinary bladder. ( 24839141 )
2014
45
A patient with eosinophilic gastroenteritis presenting with acute pancreatitis and ascites. ( 24672666 )
2014
46
Eosinophilic gastroenteritis associated with allergic asthma and atopic eczema. ( 24384450 )
2014
47
Eosinophilic gastroenteritis: the new imitator. ( 25254543 )
2014
48
Author's reply to the comment titled "Eosinophilic gastroenteritis: the new imitator". ( 25417636 )
2014
49
Eosinophilic gastroenteritis and related eosinophilic disorders. ( 24813518 )
2014
50
A case of eosinophilic gastroenteritis with perforative peritonitis. ( 24390261 )
2014

Variations for Eosinophilic Gastroenteritis

Expression for Eosinophilic Gastroenteritis

Search GEO for disease gene expression data for Eosinophilic Gastroenteritis.

Pathways for Eosinophilic Gastroenteritis

Pathways related to Eosinophilic Gastroenteritis according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 CCL11 CSF2 EPX IL3 IL5 RNASE3
2
Show member pathways
12.95 ALB CSF2 IL3 IL5
3
Show member pathways
12.92 CCL11 CSF2 IL3 IL5
4
Show member pathways
12.23 CSF2 IL3 IL5
5
Show member pathways
12.09 CCL11 EPX IL3 IL5 RNASE3
6
Show member pathways
12 CCL11 CSF2 IL5
7
Show member pathways
11.89 CSF2 IL3 IL5
8
Show member pathways
11.82 CSF2 IL3 IL5
9 11.68 CSF2 IL3 IL5
10 11.57 CSF2 IL3 IL5
11 11.49 CSF2 IL5
12
Show member pathways
11.43 CSF2 IL3 IL5
13 11.35 CCL11 IL5
14 11.3 CCL11 CSF2 IL5
15 11.18 CCL11 IL5
16 11.11 CSF2 IL3 IL5
17 10.69 CCL11 CSF2 IL3 IL5
18 10.28 CSF2 IL3 IL5

GO Terms for Eosinophilic Gastroenteritis

Cellular components related to Eosinophilic Gastroenteritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 ALB CCL11 CSF2 EPX IL3 IL5
2 extracellular space GO:0005615 9.17 ALB CCL11 CSF2 EPX IL3 IL5

Biological processes related to Eosinophilic Gastroenteritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of GTPase activity GO:0043547 9.62 CCL11 CSF2 IL3 IL5
2 MAPK cascade GO:0000165 9.54 CSF2 IL3 IL5
3 cellular oxidant detoxification GO:0098869 9.46 ALB EPX
4 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.43 CSF2 IL3
5 peptidyl-tyrosine phosphorylation GO:0018108 9.43 CSF2 IL3 IL5
6 positive regulation of DNA replication GO:0045740 9.4 CSF2 IL3
7 immune response GO:0006955 9.26 CCL11 CSF2 IL3 IL5
8 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.16 CSF2 IL3
9 positive regulation of podosome assembly GO:0071803 8.62 CSF2 IL5

Molecular functions related to Eosinophilic Gastroenteritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.43 CSF2 IL3 IL5
2 growth factor activity GO:0008083 9.33 CSF2 IL3 IL5
3 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.13 CSF2 IL3 IL5
4 cytokine activity GO:0005125 8.92 CCL11 CSF2 IL3 IL5

Sources for Eosinophilic Gastroenteritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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