MCID: ESN006
MIFTS: 32

Eosinophilic Meningitis malady

Category: Neuronal diseases

Aliases & Classifications for Eosinophilic Meningitis

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Aliases & Descriptions for Eosinophilic Meningitis:

Name: Eosinophilic Meningitis 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:10361
SNOMED-CT62 25671008
ICD9CM32 322.1

Summaries for Eosinophilic Meningitis

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MalaCards based summary: Eosinophilic Meningitis is related to gnathomiasis and meningitis. An important gene associated with Eosinophilic Meningitis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are IgA-Producing B Cells in the Intestine and Inflammatory Response Pathway. Affiliated tissues include brain and endothelial, and related mouse phenotypes are digestive/alimentary and reproductive system.

Related Diseases for Eosinophilic Meningitis

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Diseases related to Eosinophilic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 125)
idRelated DiseaseScoreTop Affiliating Genes
1gnathomiasis10.9
2meningitis10.7
3mechanical ectropion10.3IL4, MMP9
4keratoconjunctivitis10.3IL4, IL5
5chronic pulmonary heart disease10.3IL4, IL5
6myositis fibrosa10.3IL4, IL5
7thomsen and becker disease10.3IL4, IL5
8acute conjunctivitis10.3IL4, IL5
9cytoplasmic body myopathy10.3IL13, IL5
10giant ganglionic hyperplasia10.3CCL11, IL5
11aortic arch interruption10.3IL13, IL5
12toxic diffuse goiter10.3IL13, IL5
13benign fibrous mesothelioma10.3IL4, IL5
14african histoplasmosis10.3IL4, IL5
15spermatic cord cancer10.3IL4, IL5
16fungal gastritis10.3CCL11, IL5
17cherry allergy10.2IL13, IL5
18multiple system atrophy, cerebellar type10.2IL4, IL5
19benign mammary dysplasia10.2CCL11, IL5
20peanut allergy10.2IL4, IL5
21papillary conjunctivitis10.2CCL11, IL4
22philophthalmiasis10.2IL4, IL5
23anterior dislocation of lens10.2CCL11, IL4
24skin disease10.2IL13, IL5
25retinal vascular disease10.2CCL11, IL4
26goat milk allergy10.2IL13, IL4
27urinary bladder small cell neuroendocrine carcinoma10.2IL13, IL5
28polyradiculoneuropathy10.2IL13, IL5
29cow milk allergy10.2IL13, IL4
30progressive relapsing multiple sclerosis10.2IL4, MMP9
31gonococcal keratitis10.2IL4, IL5
32abdominal tuberculosis10.2IL13, IL4
33autoimmune neuropathy10.2IL13, IL5
34pediatric germ cell cancer10.1IL13, IL5
35nervous system cancer10.1IL4, MMP9
36wissler's syndrome10.1IL4, IL5
37x-linked intellectual disability, siderius type10.1IL13, IL5
38juvenile dermatitis herpetiformis10.1CCL11, IL4
39lung sarcoma10.1IL4, IL5
40gonococcal synovitis10.1IL4, IL5, MMP9
41peritonitis10.1MMP9, PLAU
42angiostrongyliasis10.1
43subcorneal pustular dermatosis10.0IL4, IL5
44palmoplantar keratosis10.0IL4, MMP9
45variola minor10.0IL13, IL4
46deafness, autosomal recessive 6210.0IL4, IL5
47intracranial hypertension10.0CCL11, IL4, MMP9
48vibrio vulnificus infection9.9CCL11, IL4, IL5
49papillary squamous carcinoma9.9IL13, IL4, IL5
50glucose intolerance9.9IL13, IL4, IL5

Graphical network of the top 20 diseases related to Eosinophilic Meningitis:



Diseases related to eosinophilic meningitis

Symptoms & Phenotypes for Eosinophilic Meningitis

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MGI Mouse Phenotypes related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5IL13, IL4, IL5, MMP9, PLAU
2MP:00053898.4IL13, IL4, IL5, MMP9, PLAU
3MP:00053978.1CCL11, IL13, IL4, IL5, MMP9, PLAU
4MP:00053878.0CCL11, IL13, IL4, IL5, MMP9, PLAU
5MP:00053887.3CCL11, IL13, IL4, IL5, MMP9, PLAU

Drugs & Therapeutics for Eosinophilic Meningitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Eosinophilic Meningitis

Genetic Tests for Eosinophilic Meningitis

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Anatomical Context for Eosinophilic Meningitis

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MalaCards organs/tissues related to Eosinophilic Meningitis:

36
Brain, Endothelial

Publications for Eosinophilic Meningitis

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Articles related to Eosinophilic Meningitis:

(show top 50)    (show all 216)
idTitleAuthorsYear
1
Comparative pathogenesis of eosinophilic meningitis caused by Angiostrongylus mackerrasae and Angiostrongylus cantonensis in murine and guinea pig models of human infection. (27278827)
2016
2
An epidemiological study of A. cantonensis in Jamaica subsequent to an outbreak of human cases of eosinophilic meningitis in 2000. (27350332)
2016
3
Eosinophilic meningitis caused by Angiostrongylus cantonensis mimicking embolic stroke. (27185606)
2016
4
Dexamethasone inhibits brain apoptosis in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection. (25890054)
2015
5
Evaluation of dot immunogold filtration assay (DIGFA) for rapid serodiagnosis of eosinophilic meningitis due to Angio-strongylus cantonensis (Nematoda: Metastrongyloidea). (25801261)
2015
6
Corticosteroids for parasitic eosinophilic meningitis. (25687750)
2015
7
Fibronectin changes in eosinophilic meningitis with blood-CSF barrier disruption. (25660199)
2015
8
Cryptococcal eosinophilic meningitis in a patient with sarcoidosis. (26682840)
2015
9
Draft genome of neurotropic nematode parasite Angiostrongylus cantonensis, causative agent of human eosinophilic meningitis. (25910624)
2015
10
Real-Time Polymerase Chain Reaction Detection of Angiostrongylus cantonensis DNA in Cerebrospinal Fluid from Patients with Eosinophilic Meningitis. (26526920)
2015
11
Eosinophilic meningitis: a case series and review of literature of Angiostrongylus cantonensis and Gnathostoma spinigerum. (25560024)
2015
12
Eosinophilic meningitis caused by Angiostrongylus cantonensis: an emergent disease in Brazil. (25075779)
2014
13
MicroRNA expressions associated with eosinophilic meningitis caused by Angiostrongylus cantonensis infection in a mouse model. (24682888)
2014
14
A rare case of Ibuprofen-induced eosinophilic meningitis in a 13-year-old girl. (24596473)
2014
15
Communicating hydrocephalus following eosinophilic meningitis is pathogenic for chronic Viliuisk encephalomyelitis in Northeastern Siberia. (24586232)
2014
16
Eosinophilic Meningitis After Bovine Dural Graft Placement in a 5-Year-Old Male. (24803627)
2014
17
Acute eosinophilic meningitis and orbital inflammation from presumed angiostrongyliasis. (24862785)
2014
18
14-3-3I^ protein expression in eosinophilic meningitis caused by Angiostrongylus cantonensis infection. (24555778)
2014
19
Eosinophilic meningitis: what's the "diff"? (24060328)
2014
20
Angiostrongylus cantonensis eosinophilic meningitis: a clinical study of 42 consecutive cases in French Polynesia. (24583335)
2014
21
Unusual Larva in the CSF and Unique MRI Findings in a Case of Eosinophilic Meningitis. (25806134)
2014
22
Eosinophilic meningitis due to Angiostrongylus cantonensis with confirmed finding of intrathecal parasite. (24676451)
2014
23
Expect the unexpected: a case of isolated eosinophilic meningitis in toxocariasis. (25535488)
2014
24
Eosinophilic meningitis caused by Angiostrongylus cantonensis - a neglected disease with escalating importance. (25776582)
2014
25
Eosinophilic meningitis caused by Angiostrongylus cantonensis in an adolescent with mental retardation and pica disorder. (23445744)
2013
26
Eosinophilic meningitis in a previously healthy 13-year-old child. (23328824)
2013
27
Medical management of eosinophilic meningitis following bovine graft duraplasty for Chiari malformation Type I repair: case report. (23909615)
2013
28
The use of albendazole and diammonium glycyrrhizinate in the treatment of eosinophilic meningitis in mice infected with Angiostrongylus cantonensis. (22152396)
2013
29
Eosinophilic meningitis secondary to intravenous vancomycin. (22842500)
2013
30
Guest Editor's message: Eosinophilic meningitis caused by Angiostrongylus cantonensis, the rat lungworm: biology, distribution, epidemiology, detection, diagnosis, treatment, and management. (23901370)
2013
31
Eosinophilic meningitis caused by primary angiitis of the central nervous system. (23774554)
2013
32
First case of neurognathostomiasis in Taiwan-A Thai laborer presenting with eosinophilic meningitis and intracranial hemorrhage. (23969044)
2013
33
Clinical aspects of eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis, the rat lungworm. (23901382)
2013
34
Severe eosinophilic meningitis owing to Angiostrongylus cantonensis in young Jamaican children: case report and literature review. (24199629)
2013
35
Eosinophilic meningitis. (23829911)
2013
36
Eosinophilic meningitis in a 10-year old nigerian boy: a case report. (24381722)
2013
37
Dexamethasone downregulated the expression of CSF 14-3-3I^ protein in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection. (24361722)
2013
38
An 8-week Brain MRI Follow-up Analysis of Rat Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection. (24207053)
2013
39
Genetic diversity of the rat lungworm, Angiostrongylus cantonensis, the major cause of eosinophilic meningitis. (23901375)
2013
40
Clinical manifestations of Eosinophilic meningitis due to infection with Angiostrongylus cantonensis in children. (24516281)
2013
41
An interesting case of eosinophilic meningitis. (23730662)
2013
42
A severe case of Angiostrongylus eosinophilic meningitis with encephalitis and neurologic sequelae in Hawa'i. (23901383)
2013
43
Molecular diagnosis of eosinophilic meningitis due to Angiostrongylus cantonensis (Nematoda: Metastrongyloidea) by polymerase chain reaction-DNA sequencing of cerebrospinal fluids of patients. (23440126)
2013
44
The first case of Angiostrongylus cantonensis eosinophilic meningitis diagnosed in the city of SALo Paulo, Brazil. (23563769)
2013
45
Curcumin alleviates eosinophilic meningitis through reduction of eosinophil count following albendazole treatment against Angiostrongylus cantonensis in mice. (22053741)
2012
46
Corticosteroids for parasitic eosinophilic meningitis. (23076953)
2012
47
Eosinophilic meningitis without peripheral eosinophilia. (22414697)
2012
48
Clinical manifestations of eosinophilic meningitis caused by Angiostrongylus cantonensis: 18 years' experience in a medical center in southern Taiwan. (21524976)
2011
49
Eosinophilic meningitis risk associated with raw Ampullarium canaliculatus snails consumption. (21527185)
2011
50
Matrix metalloproteinase-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis. (21856305)
2011

Variations for Eosinophilic Meningitis

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Expression for genes affiliated with Eosinophilic Meningitis

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Search GEO for disease gene expression data for Eosinophilic Meningitis.

Pathways for genes affiliated with Eosinophilic Meningitis

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Pathways related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 24)
idSuper pathwaysScoreTop Affiliating Genes
19.5IL4, IL5
29.5IL4, IL5
39.5MMP9, PLAU
4
Show member pathways
9.5MMP9, PLAU
59.5MMP9, PLAU
69.5MMP9, PLAU
79.5MMP9, PLAU
89.5MMP9, PLAU
99.1CCL11, IL4, IL5
10
Show member pathways
9.0CCL11, IL4, YWHAB
11
Show member pathways
8.7IL13, IL5, YWHAB
128.7IL13, IL4, IL5
138.7IL13, IL4, IL5
148.7IL13, IL4, IL5
15
Show member pathways
8.7IL13, IL4, IL5
16
Show member pathways
8.7IL13, IL4, IL5
178.7IL13, IL4, IL5
188.7IL13, IL4, IL5
198.3CCL11, IL13, IL4, IL5
208.3CCL11, IL13, IL4, IL5
21
Show member pathways
8.3CCL11, IL13, IL4, IL5
22
Show member pathways
8.3CCL11, IL13, IL4, IL5
23
Show member pathways
8.3CCL11, IL13, IL4, IL5
24
Show member pathways
7.7CCL11, IL13, IL4, IL5, YWHAB

GO Terms for genes affiliated with Eosinophilic Meningitis

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Cellular components related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.5CCL11, IL13, IL5, MMP9, PLAU
2extracellular spaceGO:00056157.3CCL11, IL13, IL4, IL5, MMP9, PLAU

Biological processes related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1embryo implantationGO:000756610.2MMP9, PLAU
2microglial cell activationGO:00017749.6IL13, IL4
3negative regulation of complement-dependent cytotoxicityGO:19036609.6IL13, IL4
4chemotaxisGO:00069359.6CCL11, IL4, PLAU
5negative regulation of endothelial cell apoptotic processGO:20003529.6IL13, IL4
6positive regulation of immunoglobulin productionGO:00026399.4IL13, IL4
7immune responseGO:00069559.3IL13, IL4, IL5
8inflammatory responseGO:00069549.3CCL11, IL13, IL5
9positive regulation of mast cell degranulationGO:00433069.2IL13, IL4
10regulation of proton transportGO:00101559.1IL13, IL4
11positive regulation of B cell proliferationGO:00308909.0IL13, IL4, IL5

Molecular functions related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.7IL13, IL4, IL5

Sources for Eosinophilic Meningitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet