MCID: ESN006
MIFTS: 33

Eosinophilic Meningitis malady

Neuronal diseases category

Aliases & Classifications for Eosinophilic Meningitis

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Aliases & Descriptions for Eosinophilic Meningitis:

Name: Eosinophilic Meningitis 10 12 65


Classifications:



External Ids:

Disease Ontology10 DOID:10361
SNOMED-CT59 25671008
ICD9CM29 322.1

Summaries for Eosinophilic Meningitis

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MalaCards based summary: Eosinophilic Meningitis is related to spotted fever and meningitis. An important gene associated with Eosinophilic Meningitis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways are Osteopontin-mediated events and Osteopontin Signaling. Affiliated tissues include brain and endothelial, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Related Diseases for Eosinophilic Meningitis

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Diseases related to Eosinophilic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 139)
idRelated DiseaseScoreTop Affiliating Genes
1spotted fever30.3IL2, IL4
2meningitis11.2
3angiostrongyliasis10.6
4meningoencephalitis10.4
5trench fever10.2IL4, IL5
6epithelioid cell melanoma10.2IL4, IL5
7mixed eosinophil-basophil adenoma10.2IL4, IL5
8status asthmaticus10.2IL4, IL5
9morgagni cataract10.2IL4, IL5
10hydrocephalus10.2
11toxocariasis10.2
12headache10.2
13hughes-stovin syndrome10.2IL4, IL5
14mechanical entropion10.2IL2, IL5
15visceral neuropathy familial10.2IL2, IL4
16epithelioid malignant peripheral nerve sheath tumor10.2IL4, IL5
17chondrocalcinosis10.2IL4, IL5
18blastomycosis10.2IL4, IL5
19cd45 deficiency10.2IL2, IL4
20microsporidiosis10.2IL2, IL4
21wells-jankovic syndrome10.2IL2, IL5
22colitis10.2IL2, IL4
23benign prostate phyllodes tumor10.1IL4, MMP9
24acute leukemia of ambiguous lineage10.1IL2, IL4
25blepharoconjunctivitis10.1IL4, MMP9
26cytokine receptor deficiency10.1IL13, IL5
27refractory hairy cell leukemia10.1IL2, IL4
28aorta atresia10.1IL13, IL5
29myxoid liposarcoma of the ovary10.1IL13, IL5
30steatorrhea10.1IL13, IL5
31alopecia areata10.1IL4, IL5
32bubonic plague10.1IL2, IL4
33synovial angioma10.1MMP9, PLAU
34soft palate cancer10.1IL2, IL4
35optic nerve sheath meningioma10.1IL13, IL5
36splenic sequestration10.1IL2, IL4
37glycogen storage disease ix10.1IL13, IL4
38de quervain disease10.1IL2, IL4
39focal chorioretinitis10.1IL2, IL5
40proximal symphalangism10.1IL4, MMP9
41clear cell renal cell carcinoma10.1IL13, IL4
42paratesticular lipoma10.1IL2, IL4
43pemphigus and fogo selvagem10.1CCL11, IL5
44limbic encephalitis with ncmags antibodies10.1IL2, IL4, IL5
45mast-cell sarcoma10.1IL2, MMP9
46sebaceous adenoma10.0IL2, IL4, IL5
47anthrax disease10.0IL2, IL4, IL5
48prostate stromal sarcoma10.0IL2, IL4
49alternating esotropia10.0IL2, IL4, IL5
50leukemia10.0

Graphical network of the top 20 diseases related to Eosinophilic Meningitis:



Diseases related to eosinophilic meningitis

Symptoms for Eosinophilic Meningitis

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Drugs & Therapeutics for Eosinophilic Meningitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Eosinophilic Meningitis

Genetic Tests for Eosinophilic Meningitis

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Anatomical Context for Eosinophilic Meningitis

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MalaCards organs/tissues related to Eosinophilic Meningitis:

33
Brain, Endothelial

Animal Models for Eosinophilic Meningitis or affiliated genes

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MGI Mouse Phenotypes related to Eosinophilic Meningitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6IL2, IL5, MMP9, PLAU
2MP:00053708.4IL2, IL4, IL5, PLAU
3MP:00053817.5IL13, IL2, IL4, IL5, MMP9, PLAU
4MP:00053787.4IL13, IL2, IL4, IL5, MMP9, PLAU
5MP:00053767.2IL13, IL2, IL4, IL5, MMP9, PLAU
6MP:00053897.2IL13, IL2, IL4, IL5, MMP9, PLAU
7MP:00053886.9CCL11, IL13, IL2, IL4, IL5, MMP9
8MP:00053876.6CCL11, IL13, IL2, IL4, IL5, MMP9
9MP:00053976.4CCL11, IL13, IL2, IL4, IL5, MMP9

Publications for Eosinophilic Meningitis

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Articles related to Eosinophilic Meningitis:

(show top 50)    (show all 211)
idTitleAuthorsYear
1
Corticosteroids for parasitic eosinophilic meningitis. (25687750)
2015
2
Eosinophilic meningitis caused by Angiostrongylus cantonensis: an emergent disease in Brazil. (25075779)
2014
3
Angiostrongylus cantonensis eosinophilic meningitis: a clinical study of 42 consecutive cases in French Polynesia. (24583335)
2014
4
MicroRNA expressions associated with eosinophilic meningitis caused by Angiostrongylus cantonensis infection in a mouse model. (24682888)
2014
5
Unusual Larva in the CSF and Unique MRI Findings in a Case of Eosinophilic Meningitis. (25806134)
2014
6
Eosinophilic meningitis caused by Angiostrongylus cantonensis in an adolescent with mental retardation and pica disorder. (23445744)
2013
7
Eosinophilic meningitis. (23829911)
2013
8
Eosinophilic meningitis in a 10-year old nigerian boy: a case report. (24381722)
2013
9
Eosinophilic meningitis in a previously healthy 13-year-old child. (23328824)
2013
10
Medical management of eosinophilic meningitis following bovine graft duraplasty for Chiari malformation Type I repair: case report. (23909615)
2013
11
Corticosteroids for parasitic eosinophilic meningitis. (23076953)
2012
12
A case report on eosinophilic meningitis caused by Angiostrongylus cantonensis. (21897764)
2011
13
Sacral myeloradiculitis (Elsberg syndrome) secondary to eosinophilic meningitis caused by Angiostrongylus cantonensis. (21811516)
2009
14
Comparison of prednisolone plus albendazole with prednisolone alone for treatment of patients with eosinophilic meningitis. (19706911)
2009
15
Eosinophilic meningitis - an immunophenotyping recording of a very rare clinical entity - brief Report. (19649744)
2009
16
Cluster of eosinophilic meningitis attributable to Angiostrongylus cantonensis infection in French policemen troop returning from the Pacific Islands. (18760253)
2008
17
A case of eosinophilic meningitis in Germany. (18481034)
2008
18
Helminthic eosinophilic meningitis: emerging zoonotic diseases in the South. (19283982)
2008
19
Detection of circulating antibody of Parastrongylus cantonensis in sera with eosinophilic meningitis by dot-blot ELISA. (18839849)
2008
20
Multi-immunodot for rapid differential diagnosis of eosinophilic meningitis due to parasitic infections. (16923267)
2006
21
Chinese herbal medicine Yin-Chen-Extract as an adjunct to anthelmintic albendazole used against Angiostrongylus cantonensis-induced eosinophilic meningitis or meningoencephalitis. (16968941)
2006
22
Upregulation of MMP-9/TIMP-1 enzymatic system in eosinophilic meningitis caused by Angiostrongylus cantonensis. (15810979)
2005
23
Multilevel intramedullary spinal neurocysticercosis with eosinophilic meningitis. (15148157)
2004
24
Combined treatment with interleukin-12 and mebendazole lessens the severity of experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice. (12819081)
2003
25
Enzootic Angiostrongylus cantonensis in rats and snails after an outbreak of human eosinophilic meningitis, Jamaica. (11927033)
2002
26
Angiostrongylus cantonensis eosinophilic meningitis. (10460929)
1999
27
Eosinophilic meningitis in a newborn with group B streptococcal infection. (8265296)
1993
28
Eosinophilic meningitis. (8356350)
1993
29
Eosinophilic meningitis. (8279176)
1993
30
Eosinophilic meningitis beyond the Pacific Basin: the global dispersal of a peridomestic zoonosis caused by Angiostrongylus cantonensis, the nematode lungworm of rats. (1738873)
1992
31
Eosinophilic meningitis in Thailand. Clinical and epidemiological characteristics of 162 patients with myeloencephalitis probably caused by Gnathostoma spinigerum. (2376755)
1990
32
Eosinophilic meningitis--a case report and literature review. (2133754)
1990
33
Eosinophilic meningitis and radiculomyelitis in Thailand, caused by CNS invasion of Gnathostoma spinigerum and Angiostrongylus cantonensis. (3351533)
1988
34
Differential diagnosis of eosinophilic meningitis. (15463120)
1988
35
Eosinophilic meningitis preceding meningeal relapse in a child with acute lymphoblastic leukemia: abnormal nucleotide content of eosinophils. (3152930)
1987
36
Leptomeningeal carcinomatosis presenting as eosinophilic meningitis. (3456181)
1986
37
The chronic and severe forms of eosinophilic meningitis. (6591910)
1984
38
Eosinophilic meningitis. (6636755)
1983
39
Eosinophilic meningitis and hydrocephalus in an infant. (7092618)
1982
40
Eosinophilic meningitis in Hodgkin disease. (7195513)
1981
41
Eosinophilic meningitis. (294917)
1979
42
Eosinophilic meningitis in Hodgkin's disease. (517907)
1979
43
Nidality of eosinophilic meningitis with special reference to Angiostrongylus cantonensis. (632707)
1978
44
Clinical observations on eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis on Taiwan. (1259085)
1976
45
Case of ocular angiostrongyliasis associated with eosinophilic meningitis. (5102754)
1971
46
Lesions of the brain in eosinophilic meningitis. (5410412)
1970
47
Eosinophilic meningitis in Thailand. Epidemiologic studies of 484 typical cases and the etiologic role of Angiostrongylus cantonensis. (5531201)
1970
48
Studies on eosinophilic meningitis. V. Molluscan hosts of Angiostrongylus cantonensis on Pacific Islands. (5777734)
1969
49
Eosinophilic meningitis in Hodgkin's disease. (5348868)
1969
50
Studies on eosinophilic meningitis. IV. Experimental infection of fresh-water and marine fish with Angiostrongylus cantonensis. (6025084)
1967

Variations for Eosinophilic Meningitis

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Expression for genes affiliated with Eosinophilic Meningitis

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Search GEO for disease gene expression data for Eosinophilic Meningitis.

Pathways for genes affiliated with Eosinophilic Meningitis

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Pathways related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 25)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MMP9, PLAU
29.5MMP9, PLAU
39.5MMP9, PLAU
49.5MMP9, PLAU
59.5MMP9, PLAU
69.5MMP9, PLAU
79.4IL13, IL2
8
Show member pathways
9.0IL13, IL2, IL5
9
Show member pathways
9.0IL13, IL2, IL5
108.8CCL11, IL4, IL5
118.8IL2, IL4, MMP9
128.7IL13, IL4, IL5
13
Show member pathways
8.7IL13, IL4, IL5
14
Show member pathways
8.7IL2, IL4, IL5
15
B cell receptor signaling pathway (KEGG)
Show member pathways
8.7IL2, IL4, IL5
168.7IL2, IL4, IL5
178.2IL13, IL2, IL4, IL5
188.2IL13, IL2, IL4, IL5
19
Show member pathways
8.2IL13, IL2, IL4, IL5
208.2IL13, IL2, IL4, IL5
21
Show member pathways
8.2IL13, IL2, IL4, IL5
22
Show member pathways
7.7CCL11, IL13, IL2, IL4, IL5
23
Show member pathways
7.7CCL11, IL13, IL2, IL4, IL5
24
Show member pathways
7.7CCL11, IL13, IL2, IL4, IL5
25
Show member pathways
7.7CCL11, IL13, IL2, IL4, IL5

GO Terms for genes affiliated with Eosinophilic Meningitis

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Cellular components related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056156.7CCL11, IL13, IL2, IL4, IL5, MMP9
2extracellular regionGO:00055766.4CCL11, IL13, IL2, IL4, IL5, MMP9

Biological processes related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of immunoglobulin secretionGO:005102410.2IL2, IL5
2negative regulation of complement-dependent cytotoxicityGO:19036609.8IL13, IL4
3regulation of proton transportGO:00101559.8IL13, IL4
4positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.8IL2, IL4
5microglial cell activationGO:00017749.7IL13, IL4
6negative regulation of endothelial cell apoptotic processGO:20003529.7IL13, IL4
7extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.7IL2, IL4
8positive regulation of activated T cell proliferationGO:00421049.7IL2, IL4
9positive regulation of isotype switching to IgG isotypesGO:00483049.7IL2, IL4
10positive regulation of T cell differentiationGO:00455829.7IL2, IL4
11positive regulation of immunoglobulin productionGO:00026399.6IL13, IL4
12positive regulation of mast cell degranulationGO:00433069.6IL13, IL4
13embryo implantationGO:00075669.5MMP9, PLAU
14inflammatory responseGO:00069549.3CCL11, IL13, IL5
15positive regulation of protein phosphorylationGO:00019349.2IL2, IL4, MMP9
16positive regulation of T cell proliferationGO:00421028.8IL2, IL4
17positive regulation of B cell proliferationGO:00308908.7IL13, IL2, IL4, IL5
18chemotaxisGO:00069358.7CCL11, IL4, PLAU
19positive regulation of cell proliferationGO:00082848.1IL2, IL4, IL5, PLAU
20immune responseGO:00069557.8CCL11, IL13, IL2, IL4, IL5

Molecular functions related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine receptor bindingGO:00051269.6IL13, IL4
2growth factor activityGO:00080838.7IL2, IL4, IL5
3cytokine activityGO:00051258.2IL13, IL2, IL4, IL5

Sources for Eosinophilic Meningitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet