Aliases & Classifications for Eosinophilic Meningitis

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Aliases & Descriptions for Eosinophilic Meningitis:

Name: Eosinophilic Meningitis 8 61


External Ids:

Disease Ontology8 DOID:10361
SNOMED-CT56 25671008
ICD9CM27 322.1

Summaries for Eosinophilic Meningitis

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MalaCards based summary: Eosinophilic Meningitis is related to meningitis and angiostrongyliasis. An important gene associated with Eosinophilic Meningitis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are Selected targets of GCR alpha and Syndecan-1-mediated signaling events. The compounds omalizumab and ovomucoid have been mentioned in the context of this disorder. Affiliated tissues include brain and endothelial, and related mouse phenotypes are tumorigenesis and no phenotypic analysis.

Related Diseases for Eosinophilic Meningitis

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Diseases related to Eosinophilic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 119)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis32.2MMP9
2angiostrongyliasis31.4MMP9
3sinusitis30.8IL5
4glioblastoma29.8PLAU, IL13, HGF, MMP9
5eosinophilia29.2IL10, CCL24, IL4, IL2, IL5, IL13
6eosinophilic fasciitis10.5IL5
7kimura disease10.5IL5
8esophagitis, eosinophilic, 110.5IL5
9malaria10.4IL10
10intraocular lymphoma10.4IL10
11periapical granuloma10.4IL4
12keratoconjunctivitis10.4IL5, IL13
13filariasis10.4IL13, IL5
14schistosomiasis10.4IL5, IL13
15parasitic helminthiasis infectious disease10.4IL5, IL13
16eosinophilic pneumonia10.3IL13, IL5
17leprosy10.3IL2
18esophagitis10.3IL5, IL13
19mastocytosis10.3IL5, IL13
20bronchiolitis10.3IL13, IL5
21egg allergy10.3IL5, IL4
22intrinsic asthma10.3IL5, IL4
23allergic bronchopulmonary aspergillosis10.3IL5, IL4
24meningoencephalitis10.3
25omenn syndrome10.3IL4, IL5
26alcoholic hepatitis10.3HGF, IL10
27dermatitis10.2IL4, IL13
28selective iga deficiency disease10.2IL4, IL10
29visceral leishmaniasis10.2IL10, IL4
30hydrocephalus10.2
31toxocariasis10.2
32headache10.2
33conjunctivochalasis10.2MMP9, PLAU
34bullous pemphigoid10.2IL5, IL13, PLAU
35abdominal aortic aneurysm10.1PLAU, MMP9
36diabetes mellitus, insulin-dependent10.1IL10, IL4
37atopic dermatitis10.1IL13, IL4
38allergic conjunctivitis10.1IL4, IL5, IL13
39asthma10.1IL13, IL5, IL4
40pulmonary eosinophilia10.1IL13, IL4, IL5
41allergic rhinitis10.1IL13, IL4, IL5
42food allergy10.1IL13, IL5, IL4
43rhinitis10.1IL4, IL5, IL13
44relapsing-remitting multiple sclerosis10.1IL10, MMP9
45bone cancer10.1MMP9, PLAU
46microvascular complications of diabetes 110.1HGF, MMP9
47pneumonia10.1IL5, IL10, IL13
48agammaglobulinemia10.1IL2, IL4
49pulmonary fibrosis, idiopathic10.1HGF, MMP9, IL13
50mycosis fungoides10.0IL2, IL5

Graphical network of the top 20 diseases related to Eosinophilic Meningitis:



Diseases related to eosinophilic meningitis

Symptoms for Eosinophilic Meningitis

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Drugs & Therapeutics for Eosinophilic Meningitis

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Drug clinical trials:

Search ClinicalTrials for Eosinophilic Meningitis

Search NIH Clinical Center for Eosinophilic Meningitis

Genetic Tests for Eosinophilic Meningitis

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Anatomical Context for Eosinophilic Meningitis

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MalaCards organs/tissues related to Eosinophilic Meningitis:

31
Brain, Endothelial

Animal Models for Eosinophilic Meningitis or affiliated genes

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MGI Mouse Phenotypes related to Eosinophilic Meningitis:

35 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020067.9PLAU, IL10, IL5, IL2, MMP9
2MP:00030127.9IL2, IL10, IL13, IL4, HGF
3MP:00053857.7IL10, IL2, MMP9, HGF, PLAU
4MP:00053707.6IL2, IL5, IL10, PLAU, HGF, IL4
5MP:00053797.5IL13, IL4, IL10, IL2, PLAU
6MP:00053817.2IL4, IL2, IL5, IL10, MMP9, PLAU
7MP:00053897.2MMP9, IL4, IL2, IL5, IL10, IL13
8MP:00053847.1MMP9, IL4, IL2, IL10, IL13, PLAU
9MP:00053767.0MMP9, IL4, IL2, IL5, IL10, IL13
10MP:00107686.8IL4, HGF, MMP9, PLAU, IL13, IL10
11MP:00053786.8MMP9, HGF, PLAU, IL13, IL10, IL5
12MP:00053886.7IL10, IL5, CCL24, IL13, PLAU, IL2
13MP:00053876.7PLAU, IL13, IL10, IL5, IL2, IL4
14MP:00053976.3CCL24, IL4, IL5, IL10, MMP9, IL13

Publications for Eosinophilic Meningitis

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Articles related to Eosinophilic Meningitis:

(show top 50)    (show all 206)
idTitleAuthorsYear
1
Corticosteroids for parasitic eosinophilic meningitis. (25687750)
2015
2
Eosinophilic meningitis caused by Angiostrongylus cantonensis: an emergent disease in Brazil. (25075779)
2014
3
Angiostrongylus cantonensis eosinophilic meningitis: a clinical study of 42 consecutive cases in French Polynesia. (24583335)
2014
4
MicroRNA expressions associated with eosinophilic meningitis caused by Angiostrongylus cantonensis infection in a mouse model. (24682888)
2014
5
Unusual Larva in the CSF and Unique MRI Findings in a Case of Eosinophilic Meningitis. (25806134)
2014
6
Eosinophilic meningitis caused by Angiostrongylus cantonensis in an adolescent with mental retardation and pica disorder. (23445744)
2013
7
Eosinophilic meningitis. (23829911)
2013
8
Eosinophilic meningitis in a 10-year old nigerian boy: a case report. (24381722)
2013
9
Eosinophilic meningitis in a previously healthy 13-year-old child. (23328824)
2013
10
Medical management of eosinophilic meningitis following bovine graft duraplasty for Chiari malformation Type I repair: case report. (23909615)
2013
11
The use of albendazole and diammonium glycyrrhizinate in the treatment of eosinophilic meningitis in mice infected with Angiostrongylus cantonensis. (22152396)
2013
12
Corticosteroids for parasitic eosinophilic meningitis. (23076953)
2012
13
A case report on eosinophilic meningitis caused by Angiostrongylus cantonensis. (21897764)
2011
14
Sacral myeloradiculitis (Elsberg syndrome) secondary to eosinophilic meningitis caused by Angiostrongylus cantonensis. (21811516)
2009
15
Comparison of prednisolone plus albendazole with prednisolone alone for treatment of patients with eosinophilic meningitis. (19706911)
2009
16
Eosinophilic meningitis - an immunophenotyping recording of a very rare clinical entity - brief Report. (19649744)
2009
17
Cluster of eosinophilic meningitis attributable to Angiostrongylus cantonensis infection in French policemen troop returning from the Pacific Islands. (18760253)
2008
18
A case of eosinophilic meningitis in Germany. (18481034)
2008
19
Helminthic eosinophilic meningitis: emerging zoonotic diseases in the South. (19283982)
2008
20
Detection of circulating antibody of Parastrongylus cantonensis in sera with eosinophilic meningitis by dot-blot ELISA. (18839849)
2008
21
Multi-immunodot for rapid differential diagnosis of eosinophilic meningitis due to parasitic infections. (16923267)
2006
22
Chinese herbal medicine Yin-Chen-Extract as an adjunct to anthelmintic albendazole used against Angiostrongylus cantonensis-induced eosinophilic meningitis or meningoencephalitis. (16968941)
2006
23
Upregulation of MMP-9/TIMP-1 enzymatic system in eosinophilic meningitis caused by Angiostrongylus cantonensis. (15810979)
2005
24
Multilevel intramedullary spinal neurocysticercosis with eosinophilic meningitis. (15148157)
2004
25
Combined treatment with interleukin-12 and mebendazole lessens the severity of experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice. (12819081)
2003
26
Enzootic Angiostrongylus cantonensis in rats and snails after an outbreak of human eosinophilic meningitis, Jamaica. (11927033)
2002
27
Angiostrongylus cantonensis eosinophilic meningitis. (10460929)
1999
28
Eosinophilic meningitis in a newborn with group B streptococcal infection. (8265296)
1993
29
Eosinophilic meningitis. (8356350)
1993
30
Eosinophilic meningitis. (8279176)
1993
31
Eosinophilic meningitis beyond the Pacific Basin: the global dispersal of a peridomestic zoonosis caused by Angiostrongylus cantonensis, the nematode lungworm of rats. (1738873)
1992
32
Eosinophilic meningitis in Thailand. Clinical and epidemiological characteristics of 162 patients with myeloencephalitis probably caused by Gnathostoma spinigerum. (2376755)
1990
33
Eosinophilic meningitis--a case report and literature review. (2133754)
1990
34
Eosinophilic meningitis and radiculomyelitis in Thailand, caused by CNS invasion of Gnathostoma spinigerum and Angiostrongylus cantonensis. (3351533)
1988
35
Differential diagnosis of eosinophilic meningitis. (15463120)
1988
36
Eosinophilic meningitis preceding meningeal relapse in a child with acute lymphoblastic leukemia: abnormal nucleotide content of eosinophils. (3152930)
1987
37
Leptomeningeal carcinomatosis presenting as eosinophilic meningitis. (3456181)
1986
38
The chronic and severe forms of eosinophilic meningitis. (6591910)
1984
39
Eosinophilic meningitis. (6636755)
1983
40
Eosinophilic meningitis and hydrocephalus in an infant. (7092618)
1982
41
Eosinophilic meningitis in Hodgkin disease. (7195513)
1981
42
Eosinophilic meningitis. (294917)
1979
43
Eosinophilic meningitis in Hodgkin's disease. (517907)
1979
44
Nidality of eosinophilic meningitis with special reference to Angiostrongylus cantonensis. (632707)
1978
45
Case of ocular angiostrongyliasis associated with eosinophilic meningitis. (5102754)
1971
46
Lesions of the brain in eosinophilic meningitis. (5410412)
1970
47
Eosinophilic meningitis in Thailand. Epidemiologic studies of 484 typical cases and the etiologic role of Angiostrongylus cantonensis. (5531201)
1970
48
Studies on eosinophilic meningitis. V. Molluscan hosts of Angiostrongylus cantonensis on Pacific Islands. (5777734)
1969
49
Eosinophilic meningitis in Hodgkin's disease. (5348868)
1969
50
Studies on eosinophilic meningitis. IV. Experimental infection of fresh-water and marine fish with Angiostrongylus cantonensis. (6025084)
1967

Variations for Eosinophilic Meningitis

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Expression for genes affiliated with Eosinophilic Meningitis

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Search GEO for disease gene expression data for Eosinophilic Meningitis.

Pathways for genes affiliated with Eosinophilic Meningitis

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Pathways related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 42)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6MMP9, HGF
29.5PLAU, MMP9
39.5PLAU, MMP9
49.5PLAU, MMP9
59.5MMP9, PLAU
69.5IL13, IL2
7
Show member pathways
IL2 signaling events mediated by STAT536
9.4IL2, IL4
8
Show member pathways
Immune response BCR pathway59
Fc-epsilon receptor I signaling in mast cells36
9.4IL13, IL5, IL4
99.4IL5, IL13, IL4
109.3HGF, IL10
11
Show member pathways
9.2IL5, IL13, IL2
12
Show member pathways
9.2IL2, IL5, IL13
139.2MMP9, HGF, PLAU
149.2MMP9, PLAU, HGF
15
Show member pathways
9.2IL2, HGF, IL5
16
Show member pathways
9.2IL5, HGF, IL2
17
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.1IL4, IL5, IL2
189.1IL5, IL2, IL4
19
Show member pathways
9.1IL4, IL13, IL2
20
Show member pathways
9.0IL2, IL10
21
Show member pathways
IL27-mediated signaling events36
9.0IL10, IL2
229.0HGF, IL4, IL2
23
Show member pathways
9.0IL4, IL2, HGF
248.9IL5, IL4, IL10
258.9MMP9, IL2, IL4
268.7IL4, IL2, IL5, IL13
278.6IL4, IL2, IL10
28
Show member pathways
8.5HGF, PLAU, IL2, MMP9
29
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.5IL10, MMP9, IL2
30
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.3IL2, IL5, IL10, IL4
317.9IL13, IL10, IL4, IL5, IL2
32
Show member pathways
Type III interferon signaling36
7.9IL10, IL13, IL2, IL4, IL5
337.9IL13, IL10, IL5, IL2, IL4
347.9IL10, IL4, IL2, IL5, IL13
35
Show member pathways
7.9IL10, IL13, IL5, IL2, IL4
36
Show member pathways
7.9IL4, IL2, IL5, IL10, IL13
37
Show member pathways
7.0CCL24, IL4, IL2, IL5, IL10, IL13
38
Show member pathways
7.0IL13, IL10, IL5, CCL24, IL2, IL4
39
Show member pathways
7.0IL10, IL5, IL4, IL2, IL13, HGF
40
Show member pathways
7.0IL5, HGF, IL13, IL10, IL2, IL4
41
Show member pathways
7.0IL10, CCL24, IL4, IL2, IL5, HGF

Compounds for genes affiliated with Eosinophilic Meningitis

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Compounds related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 186)
idCompoundScoreTop Affiliating Genes
1omalizumab44 1110.6IL13, IL5, IL4
2ovomucoid449.4IL13, IL4, IL5
3fluticasone propionate44 50 60 1112.1IL13, MMP9, IL5, IL4
4salmeterol44 50 28 1112.1IL4, IL2, IL13, IL5
5praziquantel44 119.9IL4, IL13, IL5, IL10
6montelukast44 50 28 1111.9IL13, IL10, IL5, IL4
7bleomycin44 119.8IL13, HGF, MMP9, IL4, IL5
8mip 1alpha448.8IL4, IL10, IL13, PLAU
9rolipram44 60 2810.8IL4, IL10, IL13, IL5
10doxycycline44 119.8MMP9, IL5, IL13, PLAU
11as 10144 609.7IL2, IL5, IL10, IL13
12interferon gamma448.7IL10, IL2, IL4
13alpha-galactosylceramide448.6IL2, IL10, IL4, IL13
14acetaldehyde28 44 2410.6HGF, PLAU, IL10, IL4
15con a448.6IL2, IL10, IL4, IL5
16polyinosinic-polycytidylic acid448.5IL4, IL2, IL5, IL10
17ivig448.5IL10, IL5, IL4, MMP9
18tarc448.4CCL24, IL4, IL5, IL10, IL13
19thalidomide44 50 60 1111.4IL10, IL2, IL5, IL13, HGF
20glatiramer acetate44 119.4IL4, IL13, IL10, IL5, IL2
21il-12448.3IL13, IL10, IL5, IL2, IL4
22gm-csf44 289.3IL10, IL5, IL2, IL4, IL13
23prednisolone44 28 1110.3IL2, HGF, IL5, IL10, IL13
24tgf beta1448.3PLAU, IL13, IL10, MMP9, HGF
25indomethacin44 28 60 1111.3HGF, IL13, IL5, PLAU, IL2, IL4
26il 10448.3IL5, IL13, IL10, IL2, IL4
27pentoxifylline44 119.3IL2, IL4, IL13, IL10
28adenylate448.3HGF, IL13, IL4, IL5, PLAU, MMP9
29ccl344 289.3IL13, MMP9, CCL24, IL10
30allergens448.2IL13, IL10, IL5, IL4
31ionomycin448.2IL13, IL2, IL10, IL5, IL4
32ribavirin44 50 1110.2MMP9, IL10, IL4, IL2
33dmso448.2IL2, HGF, IL5, IL10, PLAU
34herbimycin a44 609.2MMP9, IL4, IL2, HGF, PLAU, IL5
35calcitriol44 60 24 1111.1IL10, IL2, IL13, PLAU, IL4
36tacrolimus44 50 119.9IL2, HGF, IL13, IL10, IL5, IL4
37paraffin447.9HGF, PLAU, IL10, IL4, MMP9, IL5
38cyclophosphamide44 50 119.7IL13, HGF, MMP9, IL4, IL2, IL10
39sb 20358044 608.7IL10, IL13, PLAU, HGF, IL4, MMP9
40ly294002447.7PLAU, MMP9, HGF, IL13, IL10, IL5
41actinomycin d447.6IL4, PLAU, HGF, MMP9, CCL24, IL2
42hydrocortisone44 1 60 1110.6IL13, IL4, IL2, IL5, IL10, PLAU
43thymidine44 248.5IL13, PLAU, IL10, HGF, IL4, IL2
44cyclosporin a44 28 609.4HGF, IL13, IL10, IL5, IL2, IL4
45dexamethasone44 50 28 1110.4MMP9, IL4, IL2, IL5, IL10, IL13
46rantes447.3CCL24, IL4, IL2, IL5, IL13, IL10
47histamine44 28 249.1IL4, CCL24, HGF, IL2, IL5, IL10
48pge2447.1PLAU, IL13, HGF, IL10, IL5, IL2
49cycloheximide447.0IL2, MMP9, IL4, HGF, PLAU, IL13
50vegf447.0IL13, MMP9, IL4, IL10, HGF, IL2

GO Terms for genes affiliated with Eosinophilic Meningitis

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Cellular components related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.9IL2, IL5, IL13, PLAU, HGF, MMP9
2extracellular spaceGO:00056155.8HGF, MMP9, CCL24, IL4, IL2, IL5

Biological processes related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1regulation of proton transportGO:001015510.0IL4, IL13
2positive regulation of immunoglobulin secretionGO:00510249.8IL2, IL5
3positive regulation of isotype switching to IgG isotypesGO:00483049.7IL4, IL2
4positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.5IL4, IL2
5regulation of isotype switchingGO:00451919.5IL10, IL4
6type 2 immune responseGO:00420929.5IL4, IL10
7positive regulation of activated T cell proliferationGO:00421049.5IL2, IL4
8positive regulation of MHC class II biosynthetic processGO:00453489.4IL10, IL4
9negative regulation of nitric oxide biosynthetic processGO:00450199.4IL10, IL4
10extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.3IL2, IL4
11chemotaxisGO:00069359.3CCL24, IL4, PLAU
12proteolysisGO:00065089.3PLAU, HGF, MMP9
13B cell differentiationGO:00301839.2IL10, IL4
14positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.1IL10, IL4, IL5
15positive regulation of B cell proliferationGO:00308909.1IL13, IL4, IL2, IL5
16positive regulation of inflammatory responseGO:00507299.0CCL24, IL2
17inflammatory responseGO:00069548.8CCL24, IL5, IL10, IL13
18immune responseGO:00069558.5IL5, IL4, CCL24, IL13, IL2
19cell-cell signalingGO:00072678.5IL2, IL10, IL13, CCL24
20negative regulation of apoptotic processGO:00430668.4IL10, HGF, IL4, IL2
21positive regulation of transcription from RNA polymerase II promoterGO:00459448.2IL4, IL2, IL10, HGF

Molecular functions related to Eosinophilic Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051257.9IL2, IL5, IL10, IL13, IL4
2growth factor activityGO:00080837.6HGF, IL10, IL5, IL2, IL4

Sources for Eosinophilic Meningitis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet