MCID: ESN016
MIFTS: 28

Eosinophilic Pustular Folliculitis malady

Category: Rare diseases

Aliases & Classifications for Eosinophilic Pustular Folliculitis

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Aliases & Descriptions for Eosinophilic Pustular Folliculitis:

Name: Eosinophilic Pustular Folliculitis 48 68
Eosinophilic Folliculitis 48 68
Eosinophilic Folliculitis, Pustular 48
 
Ofuji's Disease 48
Ofuji Disease 48
Epf 48

Classifications:



Summaries for Eosinophilic Pustular Folliculitis

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NIH Rare Diseases:48 Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females. There are several variants of EPF including classic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known. Several treatments have been described with variable results, including various oral or topical medications and phototherapy. In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition. Last updated: 12/5/2016

MalaCards based summary: Eosinophilic Pustular Folliculitis, also known as eosinophilic folliculitis, is related to folliculitis and lymphoma, and has symptoms including dry skin, warm skin and burning sensation of skin. An important gene associated with Eosinophilic Pustular Folliculitis is IFNG (Interferon Gamma), and among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Lymphoid Cell Differentiation Pathways. Affiliated tissues include skin, breast and testes.

Wikipedia:71 Eosinophilic folliculitis (also known as \"Eosinophilic pustular folliculitis\" and \"Sterile... more...

Related Diseases for Eosinophilic Pustular Folliculitis

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Diseases related to Eosinophilic Pustular Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1folliculitis11.0
2lymphoma10.0
3cellulitis10.0
4follicular mucinosis10.0
5eosinophilia10.0
6hodgkin lymphoma9.9
7hepatitis c virus9.9
8myelodysplastic syndrome9.9
9mycosis fungoides9.9
10hepatitis9.9
11hepatitis c9.9
12basal cell carcinoma9.9
13neuronitis9.9
14polycythemia9.9
15pulmonary eosinophilia9.9
16eosinophilic mastitis9.6IFNG, PTGDR2
17cervix melanoma9.5IFNG, PTGDR2
18asthma9.5IFNG, PTGDR2
19buphthalmos9.5IFNG, PTGDR2
20blind hypotensive eye9.3IFNG, PTGDR2

Graphical network of diseases related to Eosinophilic Pustular Folliculitis:



Diseases related to eosinophilic pustular folliculitis

Symptoms & Phenotypes for Eosinophilic Pustular Folliculitis

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UMLS symptoms related to Eosinophilic Pustular Folliculitis:


dry skin, warm skin, burning sensation of skin, pain of skin, macule, peau d'orange surface of breast, macerated skin (finding), yellow complexion, skin discomfort, painful scar, application site papules, eyelid margin crusting, eyelid pain, injection site dryness, eyelid skin dryness, pathergy reaction

Drugs & Therapeutics for Eosinophilic Pustular Folliculitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Eosinophilic Pustular Folliculitis

Genetic Tests for Eosinophilic Pustular Folliculitis

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Anatomical Context for Eosinophilic Pustular Folliculitis

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MalaCards organs/tissues related to Eosinophilic Pustular Folliculitis:

36
Skin, Breast, Testes, Bone marrow, Bone, Neutrophil, B cells

Publications for Eosinophilic Pustular Folliculitis

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Articles related to Eosinophilic Pustular Folliculitis:

(show top 50)    (show all 159)
idTitleAuthorsYear
1
Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms. (27028427)
2016
2
Pilosebaceous Targeting by Isotretenoin Loaded Invasomal Gel for the Treatment of Eosinophilic Pustular Folliculitis: Optimization, efficacy and cellular analysis. (27649797)
2016
3
Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness. (26875627)
2016
4
Eosinophilic pustular folliculitis: Trends in therapeutic options. (26876326)
2016
5
Case of generalized eosinophilic pustular folliculitis induced by allopurinol. (26666426)
2016
6
Eosinophilic pustular folliculitis in a patient with mycosis fungoides. (25678045)
2015
7
Eosinophilic Pustular Folliculitis Post Chemotherapy in a Patient of Non-Hogkins Lymphoma: A Case Report. (26538725)
2015
8
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature. (26362415)
2015
9
Eosinophilic pustular folliculitis: The transition in sex differences and interracial characteristics between 1965 and 2013. (25675987)
2015
10
Clinical epidemiology of eosinophilic pustular folliculitis: results from a nationwide survey in Japan. (25503295)
2015
11
Vesicles and pustules on the fingers as an initial manifestation of eosinophilic pustular folliculitis. (26011016)
2015
12
Generalized Eosinophilic Pustular Folliculitis of Infancy Responding to Hydroxyzine. (26273169)
2015
13
Two cases of eosinophilic pustular folliculitis associated with pregnancy. (26499866)
2015
14
Widespread eosinophilic pustular folliculitis in a nonimmunocompromised patient. (24751524)
2014
15
Eosinophilic pustular folliculitis: association with long-term immunosuppressant use in a solid organ transplant recipient. (25143686)
2014
16
Eosinophilic pustular folliculitis associated with SAczary syndrome. (24708187)
2014
17
Induction of CD163+ M2 Macrophages in the Lesional Skin of Eosinophilic Pustular Folliculitis. (23604082)
2014
18
Eosinophilic pustular folliculitis with extensive distribution: correlation of serum TARC levels and peripheral blood eosinophil numbers. (24697527)
2014
19
Infantile case of eosinophilic pustular folliculitis successfully treated with topical indomethacin. (24433329)
2014
20
Hyperimmunoglobulin E syndrome presenting as eosinophilic pustular folliculitis: a case report. (24739054)
2014
21
Refractory eosinophilic pustular folliculitis resistant to oral indomethacin successfully treated with adjuvant topical indomethacin. (25182296)
2014
22
Eosinophilic Pustular Folliculitis Clinically Presenting as Orofacial Granuloma: Successful Treatment with Indomethacin, But Not Ibuprofen. (24979363)
2014
23
Eosinophilic pustular folliculitis: a review of the Japanese published works. (23083212)
2013
24
Facial and Extra-facial Eosinophilic Pustular Folliculitis: A Clinical and Histopathological Comparative Study. (24341854)
2013
25
Eosinophilic pustular folliculitis involving labial mucosa, which improved with naproxen. (23463836)
2013
26
Evaluation of the Effectiveness of Antibiotics against Eosinophilic Pustular Folliculitis. (23741214)
2013
27
Indomethacin for refractory infantile eosinophilic pustular folliculitis. (23552848)
2013
28
Extended eosinophilic pustular folliculitis with reactive bone marrow hypereosinophilia responsive to combined treatment with indomethacin, dapsone, and narrow-band UVB phototherapy. (24238194)
2013
29
Indomethacin inhibits eosinophil migration to prostaglandin D2 : therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis. (23582181)
2013
30
Acrosyringeal involvement of palmoplantar lesions of eosinophilic pustular folliculitis. (22504923)
2013
31
Immunosuppression-associated eosinophilic pustular folliculitis (IS-EPF) developing after Highly Active Anti-Retroviral Therapy (HAART): the possible mechanisms through CD163+ M2 macrophages. (24213586)
2013
32
Eosinophilic pustular folliculitis of infancy: a series of 15 cases and review of the literature. (22819356)
2013
33
Transdermal nicotine patches for eosinophilic pustular folliculitis. (23802575)
2013
34
Intractable erythematous plaques on the hands: palmoplantar eosinophilic pustular folliculitis. (24073908)
2013
35
Clinical and histopathological differential diagnosis of eosinophilic pustular folliculitis. (23488969)
2013
36
Atypical clinical appearance of eosinophilic pustular folliculitis of seborrheic areas of the face. (22940757)
2012
37
A case of eosinophilic pustular folliculitis with response to infliximab. (22980264)
2012
38
Cover quizlet: recurrent pustules on the scalp of an infant. Eosinophilic pustular folliculitis. (22905683)
2012
39
Eosinophilic pustular folliculitis in infancy: report of a new case. (23122013)
2012
40
Eosinophilic pustular folliculitis (Ofuji's disease) without macroscopic pustules. (21790551)
2012
41
PGD2 induces eotaxin-3 via PPARI^ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis. (22206772)
2012
42
Successful treatment of eosinophilic pustular folliculitis with topical tacrolimus 0.1 percent ointment. (22398231)
2012
43
Comparison of basophil infiltration into the skin between eosinophilic pustular folliculitis and neutrophilic folliculitis. (21521381)
2012
44
Recalcitrant eosinophilic pustular folliculitis of Ofuji with palmoplantar pustulosis: dramatic response to narrowband UVB phototherapy. (23017177)
2012
45
Basophils infiltrate skin lesions of eosinophilic pustular folliculitis (Ofuji's disease). (21279304)
2011
46
Case of eosinophilic pustular folliculitis associated with pregnancy. (21545495)
2011
47
Dermacase. Can you identify this condition? Eosinophilic pustular folliculitis. (21673217)
2011
48
Eosinophilic pustular folliculitis: case report and review of the literature. (21140927)
2010
49
Erythematous and edematous eruption of the face. Eosinophilic pustular folliculitis. (20883260)
2010
50
Treatment of eosinophilic pustular folliculitis with ciclosporin: suppression of mRNA expression of IL-4 and IL-13. (20384684)
2010

Variations for Eosinophilic Pustular Folliculitis

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Expression for genes affiliated with Eosinophilic Pustular Folliculitis

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Search GEO for disease gene expression data for Eosinophilic Pustular Folliculitis.

Pathways for genes affiliated with Eosinophilic Pustular Folliculitis

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Pathways related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1IFNG, PTGDR2
29.1IFNG, PTGDR2

GO Terms for genes affiliated with Eosinophilic Pustular Folliculitis

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Cellular components related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intracellularGO:00056229.8IFNG, PTGDR2
2neuron projectionGO:00430059.1IFNG, PTGDR2

Sources for Eosinophilic Pustular Folliculitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet