MCID: EPN002
MIFTS: 62

Ependymoma malady

Genetic diseases, Rare diseases, Neuronal diseases, Cancer diseases categories
Download this MalaCard

Summaries for Ependymoma

About this section
Sources:
65Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard
Wikipedia:65 Ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in... more...

MalaCards: Ependymoma, also known as tanycytic ependymoma, is related to myxopapillary ependymoma and anaplastic ependymoma. An important gene associated with Ependymoma is RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A), and among its related pathways are Epstein-Barr virus infection and IL-9 Signaling Pathways. The drug carmustine and the compounds eosin and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related mouse phenotypes are respiratory system and limbs/digits/tail.

Aliases & Classifications for Ependymoma

About this section
Sources:
43NIH Rare Diseases, 62UMLS, 45Novoseek, 49Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases, Cancer diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

49
ependymoma:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

ependymoma 43 45 49 62
tanycytic ependymoma 43 62
papillary ependymoma 43 62
cellular ependymoma 43 62
clear cell ependymoma 43
ependymoma, familial 43


External Ids:

SNOMED-CT via Orphanet59 443643007
UMLS via Orphanet63 C0014474

Related Diseases for Ependymoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Ependymoma family:

Malignant Adult Ependymoma Benign Ependymoma
Malignant Ependymoma

Diseases related to Ependymoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 227)
idRelated DiseaseScoreTop Affiliating Genes
1myxopapillary ependymoma31.6GFAP, S100B
2anaplastic ependymoma31.2GFAP, PTEN, MUC1, S100B, NF2, MDM2
3spinal cord ependymoma31.2NF2, HOXB13
4tanycytic ependymoma31.1GFAP, NF2
5clear cell ependymoma31.1VIM, MUC1
6malignant ependymoma30.9GFAP, NF2
7papillary ependymoma30.8GFAP, SYP, S100B
8choroid plexus papilloma30.5GFAP
9oligodendroglioma30.5PTEN, GFAP, MGMT
10medulloblastoma30.5MGMT, GFAP, NGFR, SYP, S100B, NCAM1
11neurofibromatosis30.4S100B, MEN1, NGFR, NF2
12meningioma30.3NF2, MKI67, GFAP, PTEN, VIM, MUC1
13astrocytoma30.3GFAP, NGFR, PTEN, VIM, SYP, S100B
14hemangioblastoma30.3GFAP, MUC1, SYP, S100B
15gliosarcoma30.1GFAP, PTEN
16multiple endocrine neoplasia30.1NF2, MEN1
17chordoma30.1GFAP, VIM, MUC1, S100B, NCAM1
18paraganglioma30.0GFAP, MEN1, SYP, S100B, NCAM1
19lipoma30.0C11orf95, PTEN, MEN1, MDM2
20pilocytic astrocytoma30.0MGMT, GFAP, PTEN, SYP, S100B
21astroblastoma30.0VIM, GFAP
22ganglioglioma29.9S100B, SYP, GFAP
23chondrosarcoma29.9MDM2, S100B, MUC1, VIM
24neuroendocrine tumor29.8MKI67, MEN1, SYP, NCAM1
25sarcoma29.8MKI67, VIM, MUC1, S100B, NF2, MDM2
26neurofibroma29.8NGFR, VIM, MUC1, SYP, S100B, NF2
27malignant glioma29.7MGMT, GFAP, NGFR, PTEN, SYP, NF2
28adenocarcinoma29.3MUC1, VIM, PTEN, NGFR, MKI67, MGMT
29pediatric ependymoma10.6
30cervicitis10.5
31choroiditis10.4
32cerebritis10.3
33hydrocephalus10.3
34cellular ependymoma10.3
35pediatric supratentorial ependymoma10.3
36siderosis10.3
37subependymoma10.3
38syringomyelia10.2
39pediatric infratentorial ependymoma10.2
40brain ependymoma10.2
41papilloma10.2
42superficial siderosis10.2
43brain stem ependymoma10.2
44back pain10.2
45headache10.2
46mixed glioma10.1GFAP
47dysembryoplastic neuroepithelial tumor10.1SYP
48melanotic neuroectodermal tumor10.1SYP
49hidradenoma10.1MUC1
50dermatofibrosarcoma10.1MDM2

Graphical network of the top 20 diseases related to Ependymoma:



Diseases related to ependymoma

Symptoms for Ependymoma

About this section

Drugs & Therapeutics for Ependymoma

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Ependymoma

Search NIH Clinical Center for Ependymoma

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Ependymoma

About this section

Anatomical Context for Ependymoma

About this section
Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Ependymoma:

33
Spinal cord, Brain, Bone, Pituitary, Medulla oblongata, Temporal lobe, Cerebellum, Liver, Lung, Ovary, Endothelial, Pineal, Olfactory bulb, Prostate, Lymph node, Cortex, Retina, Skin

Animal Models for Ependymoma or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Ependymoma:

37 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.7NF2, RELA, VIM, PTEN, NGFR
2MP:00053718.6HOXB13, NGFR, PTEN, RELA, MDM2
3MP:00053828.4NGFR, PTEN, MEN1, NF2, MDM2
4MP:00053818.4GFAP, NGFR, PTEN, MUC1, RELA, MEN1
5MP:00053708.4NGFR, PTEN, MUC1, RELA, MEN1, NF2
6MP:00020068.3MGMT, PTEN, MUC1, MEN1, NF2, MDM2
7MP:00053698.3GFAP, NGFR, PTEN, VIM, RELA, MEN1
8MP:00053808.3HOXB13, PTEN, VIM, RELA, MEN1, NF2
9MP:00107718.1HOXB13, NGFR, PTEN, MUC1, RELA, S100B
10MP:00053858.1GFAP, NGFR, PTEN, VIM, RELA, MEN1
11MP:00028738.1GFAP, NGFR, PTEN, MUC1, RELA, SYP
12MP:00053798.1HOXB13, MGMT, PTEN, MUC1, RELA, MEN1
13MP:00053898.0HOXB13, PTEN, VIM, MEN1, NF2, MDM2
14MP:00053877.9GFAP, NGFR, PTEN, VIM, RELA, MEN1
15MP:00053917.7GFAP, NGFR, PTEN, VIM, MUC1, RELA
16MP:00053767.3MGMT, GFAP, NGFR, PTEN, VIM, MUC1
17MP:00053867.2HOXB13, GFAP, NGFR, PTEN, VIM, S100B
18MP:00053787.2GFAP, NGFR, PTEN, VIM, RELA, MEN1
19MP:00053847.1HOXB13, GFAP, NGFR, PTEN, VIM, RELA
20MP:00107686.6MGMT, GFAP, NGFR, PTEN, VIM, RELA
21MP:00036316.5MDM2, HOXB13, GFAP, NGFR, PTEN, VIM

Publications for Ependymoma

About this section
Sources:
52PubMed
See all sources

Articles related to Ependymoma:

(show top 50)    (show all 749)
idTitleAuthorsYear
1
Treatment of Ovarian Anaplastic Ependymoma by an Aromatase Inhibitor. (24413241)
2014
2
Tanycytic ependymoma of the filum terminale associated with multiple endocrine neoplasia type 1: first reported case. (23562332)
2013
3
Peroxiredoxins and their expression in ependymomas. (23076395)
2013
4
Resection of filum terminale ependymoma. (23417748)
2013
5
Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression. (23371454)
2013
6
Myxopapillary ependymoma in the third ventricle area and sacral canal: dropped or retrograde metastasis? (23615415)
2013
7
A cortical cystic epileptogenic lesion: tanycytic ependymoma. (23160807)
2013
8
Management of pediatric myxopapillary ependymoma: the role of adjuvant radiation. (22713833)
2013
9
Subcutaneous sacrococcygeal myxopapillary ependymoma in asian female:a case report. (22383930)
2012
10
Metronomic cyclophosphamide with cisplatin and bevacizumab: a new chemotherapeutic regimen for refractory anaplastic ependymoma. (23155280)
2012
11
Pediatric infratentorial ependymoma: prognostic significance of anaplastic histology. (21863401)
2012
12
Evaluating the incidence and utility of microscopic metastatic dissemination as diagnosed by lumbar cerebro-spinal fluid (CSF) samples in children with newly diagnosed intracranial ependymoma. (21038109)
2011
13
Supratentorial clear cell ependymoma mimicking oligodendroglioma : case report and review of the literature. (22102956)
2011
14
Molecular genetics of ependymoma. (21959044)
2011
15
Intracranial ependymoma associated with multiple endocrine neoplasia type 1. (20142633)
2010
16
Proton beam therapy following resection for childhood ependymoma. (20024657)
2010
17
Utility of cerebrospinal fluid cytology in newly diagnosed childhood ependymoma. (20463607)
2010
18
Pigmented ependymoma with signet-ring cells and Rosenthal fibers: a rare variant of ependymoma. (19508348)
2010
19
Conus ependymoma with holocord syringomyelia. (19587487)
2009
20
Survival following treatment for intracranial ependymoma: a review. (19387655)
2009
21
Expression of leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins in human ependymoma relates to tumor location, WHO grade, and patient age. (19216216)
2009
22
Evolution of neurological impairment in pediatric infratentorial ependymoma patients. (19330288)
2009
23
Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. (19274783)
2009
24
Cytokine and growth factor responses after radiotherapy for localized ependymoma. (19019565)
2009
25
Recurrent ependymoma with cartilaginous metaplasia in an adult: report of a rare case and review of literature. (19353841)
2009
26
Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningioma. (19521276)
2009
27
Giant cell ependymoma of the thoracic spine: pathology case report. (19240583)
2009
28
Sacral myxopapillary ependymoma with extensive osteolysis. (17952371)
2008
29
Conus ependymoma with holocord syringohydromyelia and syringobulbia. (17660060)
2007
30
Case report: primary subcutaneous sacrococcygeal ependymoma: a case report and review of the literature. (16632628)
2006
31
Intradural extramedullary spinal anaplastic ependymoma. Case illustration. (17120902)
2006
32
Myxopapillary ependymoma with intracranial metastases. (16455546)
2005
33
Extra-axial ependymoma of posterior fossa extending to the Meckel's cave. (15885395)
2005
34
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. (16215459)
2005
35
Stromal cells in hemangioblastoma: neuroectodermal differentiation and morphological similarities to ependymoma. (15982211)
2005
36
Large supratentorial ectopic ependymoma with massive calcification and cyst formation--case report. (15508351)
2004
37
Light microscopic demonstration of the microlumen of ependymoma: a study of the usefulness of antigen retrieval for epithelial membrane antigen (EMA) immunostaining. (15696964)
2004
38
Distribution of the extracellular matrix glycoproteins in ependymomas--an immunohistochemical study with follow-up analysis. (15254676)
2004
39
Experience with tamoxifen/etoposide in the treatment of a child with myxopapillary ependymoma. (11466729)
2001
40
Tanycytic ependymoma in association with neurofibromatosis type 2. (11430494)
2001
41
Neuroradiology case of the day. Myxopapillary ependymoma of the conus medullaris or filum terminale resulting in superficial siderosis and dissemination of tumor along CSF pathways. (9599402)
1998
42
Anaplastic ependymoma: treatment of pediatric patients with or without craniospinal radiation therapy. (9171172)
1997
43
Efficacy and feasibility of stereotactic radiosurgery in the primary management of unfavorable pediatric ependymoma. (9215786)
1997
44
Tanycytic ependymoma. (9090024)
1997
45
Expression of platelet-derived growth factor transcripts in medulloblastomas and ependymomas. (8841077)
1996
46
TGF beta 1 and TGF beta 2 are potential growth regulators for medulloblastomas, primitive neuroectodermal tumors, and ependymomas: evidence in support of an autocrine hypothesis. (8200640)
1994
47
Intramedullary abscess associated with a spinal cord ependymoma: case report. (1738441)
1992
48
Mixed ependymoma-astrocytoma (subependymoma?) of the cerebral cortex. (3201927)
1988
49
Case report 435: Myxopapillary ependymoma of filum terminale with massive bone destruction of sacrum. (3659996)
1987
50
Myxopapillary ependymoma of the lateral ventricle. A study on the mechanism of its stromal myxoid change. (6359815)
1983

Variations for Ependymoma

About this section

Expression for genes affiliated with Ependymoma

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Ependymoma

Search GEO for disease gene expression data for Ependymoma.

Pathways for genes affiliated with Ependymoma

About this section
Sources:
50PathCards, 30KEGG, 54R&D Systems, 38NCBI BioSystems Database, 60Thomson Reuters, 53QIAGEN, 61Tocris Bioscience, 12EMD Millipore, 5Cell Signaling Technology, 55Reactome
See all sources

Pathways related to Ependymoma according to GeneCards/GeneDecks:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6MDM2, RELA, VIM
2
Show member pathways
IL-9 Signaling Pathway38
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway38
Immune response IL 9 signaling pathway60
9.5RELA, MUC1, PTEN
3
Show member pathways
9.5NGFR, RELA, MDM2
49.5GFAP, NGFR, VIM
5
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
9.4PTEN, VIM, RELA
6
Show member pathways
Signaling Pathways in Glioblastoma38
9.4MDM2, RELA, PTEN
7
Show member pathways
Immune response IL 4 signaling pathway60
Signal transduction AKT signaling60
9.4MDM2, RELA, PTEN
8
Show member pathways
Signal transduction PTEN pathway60
9.4MDM2, RELA, PTEN
99.4PTEN, RELA, MDM2
10
Show member pathways
Translation Non genomic rapid action of Androgen Receptor60
9.4MDM2, RELA, PTEN
11
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor38
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
9.3NGFR, PTEN, RELA
129.3MEN1, RELA, MGMT
139.1NGFR, RELA, MEN1, MDM2
149.0NCAM1, RELA, NGFR
159.0NGFR, PTEN, RELA, MDM2
16
Show member pathways
9.0NGFR, PTEN, RELA, MDM2
17
Show member pathways
8.9GFAP, PTEN, RELA, S100B, MDM2
188.7MDM2, NF2, PTEN, MGMT
19
Show member pathways
8.4GFAP, NGFR, PTEN, VIM, MUC1, MDM2
20
Show member pathways
8.1GFAP, NGFR, PTEN, RELA, MEN1, S100B
217.5NF2, NCAM1, S100B, SYP, NGFR, GFAP

Compounds for genes affiliated with Ependymoma

About this section
Sources:
45Novoseek, 24HMDB, 11DrugBank, 51PharmGKB, 61Tocris Bioscience, 29IUPHAR, 3BitterDB
See all sources

Compounds related to Ependymoma according to GeneCards/GeneDecks:

(show top 50)    (show all 123)
idCompoundScoreTop Affiliating Genes
1eosin459.8S100B, GFAP, VIM, MUC1
2mucicarmine459.6SYP, S100B, MUC1, VIM
3b 723459.5SYP, S100B, VIM, MUC1
4s 100459.4VIM, GFAP, S100B, MUC1, SYP
5reticulin459.4GFAP, MUC1, SYP, S100B, VIM
6dutp459.2MKI67, GFAP, MDM2, SYP
7streptozotocin459.1SYP, MGMT, GFAP, VIM
8choline45 24 1111.0GFAP, SYP, NGFR, VIM, S100B
9forskolin45 51 1110.8GFAP, SYP, S100B, MUC1, VIM, NGFR
10bromodeoxyuridine458.6GFAP, VIM, NCAM1, S100B, MKI67
11ganglioside458.6GFAP, NGFR, SYP, NCAM1, VIM
12methotrexate51 45 1110.5MGMT, MDM2, VIM, MUC1, MKI67
13agar458.5MUC1, NF2, VIM, GFAP, NGFR, MDM2
14matrigel458.4GFAP, NGFR, VIM, MUC1, NCAM1
15dbc-amp458.4NCAM1, GFAP, NGFR, VIM, SYP, S100B
16etoposide45 51 61 1111.4PTEN, VIM, S100B, MGMT, MDM2, SYP
17gaba458.3S100B, VIM, GFAP, NCAM1, SYP, NGFR
18formaldehyde45 249.3S100B, SYP, MUC1, VIM, GFAP, MKI67
19acetylcholine45 51 29 24 1112.3SYP, GFAP, NGFR, VIM, S100B, NCAM1
20estradiol45 24 1110.3MUC1, SYP, PTEN, MDM2, GFAP, MKI67
21genistein45 29 61 3 24 1113.3PTEN, SYP, MGMT, MDM2, VIM, GFAP
225fluorouracil458.2MDM2, MUC1, MGMT, MKI67, PTEN
23creatinine458.1GFAP, VIM, MUC1, SYP, S100B, NCAM1
24cyclic amp45 249.1GFAP, MDM2, S100B, SYP, MUC1, VIM
25glycogen45 249.1MDM2, S100B, MUC1, MKI67, VIM, GFAP
26paclitaxel45 51 1110.0VIM, MDM2, S100B, MGMT, MKI67, GFAP
27oxygen45 249.0MKI67, GFAP, PTEN, MUC1, RELA, NGFR
28leucine458.0GFAP, NGFR, PTEN, VIM, SYP, S100B
29cisplatin45 51 61 1110.9SYP, MDM2, MUC1, GFAP, MKI67, MGMT
30lactate457.8MGMT, S100B, NCAM1, MKI67, GFAP, VIM
31thymidine45 248.8MKI67, GFAP, MUC1, MEN1, S100B, MDM2
32glutamate457.8MDM2, NCAM1, S100B, SYP, NGFR, GFAP
33vincristine45 51 119.7MGMT, PTEN, VIM, NCAM1, MDM2, MKI67
34doxorubicin45 51 119.6MDM2, MKI67, VIM, MGMT, NCAM1, PTEN
35ethanol45 51 24 1110.4MKI67, NGFR, PTEN, MUC1, SYP, GFAP
36dexamethasone45 51 29 1110.2SYP, MUC1, VIM, MGMT, S100B, NCAM1
37threonine457.2NGFR, MUC1, S100B, GFAP, NF2, MDM2
38hematoxylin457.1MKI67, NCAM1, S100B, SYP, MUC1, VIM
39testosterone45 61 24 1110.0MKI67, GFAP, PTEN, MUC1, RELA, SYP
40lipid457.0MKI67, MUC1, SYP, NCAM1, NGFR, PTEN
41nitric oxide45 24 118.7NCAM1, MGMT, MKI67, NGFR, MDM2, S100B
42retinoic acid45 247.5SYP, MGMT, NCAM1, S100B, MUC1, VIM
43cysteine456.4SYP, MGMT, S100B, MDM2, NF2, NCAM1
44tyrosine456.4MKI67, GFAP, NGFR, PTEN, MUC1, S100B
45serine455.9NF2, GFAP, MEN1, MUC1, VIM, SYP
46progesterone45 29 61 24 119.9GFAP, MKI67, MGMT, MDM2, NF2, NCAM1
47calcium45 51 24 118.8MDM2, SYP, NCAM1, MEN1, RELA, MUC1
48estrogen455.8S100B, NCAM1, MDM2, SYP, MEN1, MUC1
49vegf455.8NGFR, PTEN, VIM, MUC1, MEN1, SYP
50paraffin455.7VIM, MGMT, NCAM1, NF2, S100B, PTEN

GO Terms for genes affiliated with Ependymoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Ependymoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.5MEN1, RELA, NGFR, MGMT, MDM2
2cytosolGO:0058298.0GFAP, MDM2, MEN1, RELA, VIM, PTEN
3nucleolusGO:0057307.8MKI67, HOXB13, MDM2, NF2, MEN1, PTEN
4nucleusGO:0056346.9MDM2, NF2, S100B, MEN1, RELA, PTEN
5cytoplasmGO:0057376.4PTEN, MUC1, GFAP, MKI67, RELA, MEN1

Biological processes related to Ependymoma according to GeneCards/GeneDecks:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:06002010.3VIM, GFAP
2astrocyte developmentGO:01400210.2GFAP, VIM
3intermediate filament organizationGO:04510910.2VIM, GFAP
4regulation of neuronal synaptic plasticityGO:04816810.0S100B, SYP
5membrane protein intracellular domain proteolysisGO:03129310.0NGFR, RELA
6response to morphineGO:0432789.9MDM2, RELA
7negative regulation of organ growthGO:0466219.9PTEN, MEN1
8long-term synaptic potentiationGO:0602919.8S100B, PTEN, GFAP
9negative regulation of neuron projection developmentGO:0109779.6VIM, GFAP
10regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0432819.6NGFR, MGMT
11negative regulation of axonogenesisGO:0507719.6PTEN, NGFR
12positive regulation of apoptotic signaling pathwayGO:20012359.5PTEN, NGFR
13central nervous system developmentGO:0074179.5NGFR, PTEN, S100B
14Fc-epsilon receptor signaling pathwayGO:0380959.3PTEN, RELA, MDM2
15positive regulation of cell proliferationGO:0082849.3MDM2, S100B, RELA, PTEN
16neurotrophin TRK receptor signaling pathwayGO:0480119.3NGFR, PTEN, RELA, MDM2
17positive regulation of apoptotic processGO:0430659.2NGFR, PTEN, MEN1, S100B
18response to drugGO:0424939.1MDM2, RELA, PTEN, MGMT
19negative regulation of apoptotic processGO:0430669.1NGFR, PTEN, RELA, MDM2

Molecular functions related to Ependymoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:0971109.9MDM2, VIM
2ubiquitin protein ligase bindingGO:0316259.2NGFR, RELA, MDM2
3identical protein bindingGO:0428028.1S100B, NCAM1, MDM2, SYP, RELA, VIM
4protein bindingGO:0055156.9MKI67, NGFR, PTEN, VIM, MUC1, RELA

Products for genes affiliated with Ependymoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ependymoma

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet