MCID: EPC002
MIFTS: 41

Epicondylitis malady

Summaries for Epicondylitis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 Epicondylitis is a type of musculoskeletal disorder that refers to an inflammation of an epicondyle. more...

MalaCards: Epicondylitis, also known as lateral epicondylitis, is related to tendinopathy and ulnar neuropathy. An important gene associated with Epicondylitis is CHAT (choline O-acetyltransferase), and among its related pathways are Sympathetic Nerve Pathway (Pre- and Post- Ganglionic Junction) and Regulation of thyroid hormone activity. The compounds ibotenic acid and homovanillic acid have been mentioned in the context of this disorder. Affiliated tissues include epicondyle, bone and whole blood.

Disease Ontology:8 A bone inflammation disease that results in inflammation located in epicondyle.

Aliases & Classifications for Epicondylitis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt, 25ICD10
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Classifications:



Aliases & Descriptions:

epicondylitis 8 10 60
lateral epicondylitis 8
medial epicondylitis 8
andrel epicondylitis 8
golfer's elbow 8
archer's elbow 8
hockey elbow 8


External Ids:

Disease Ontology8 DOID:14087
NCIt39 C34589
ICD1025 M77.0, M77.1

Related Diseases for Epicondylitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Epicondylitis:



Diseases related to epicondylitis

Clinical Features for Epicondylitis

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Drugs & Therapeutics for Epicondylitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Epicondylitis

Drug clinical trials:

Search ClinicalTrials for Epicondylitis

Search NIH Clinical Center for Epicondylitis

Search CenterWatch for Epicondylitis

Genetic Tests for Epicondylitis

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Anatomical Context for Epicondylitis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Epicondylitis:

32
Bone, Whole blood, Skin

FMA organs/tissues related to Epicondylitis:

14
Epicondyle

Animal Models for Epicondylitis or affiliated genes

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Publications for Epicondylitis

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50PubMed
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Articles related to Epicondylitis:

(show top 50)    (show all 408)
idTitleAuthorsYear
1
MR Imaging of Patients with Lateral Epicondylitis of the Elbow: Is the Common Extensor Tendon an Isolated Lesion? (24244512)
2013
2
Risk factors in lateral epicondylitis (tennis elbow): a case-control study. (22490998)
2013
3
Platelet-rich plasma for the treatment of lateral epicondylitis: sonographic assessment of tendon morphology and vascularity (pilot study). (23001116)
2013
4
Ganglion cyst of radiocapitellar joint mimicking lateral epicondylitis: role of ultrasonography. (22377826)
2013
5
The effectiveness of therapeutic class IV (10 W) laser treatment for epicondylitis. (23733499)
2013
6
Ultra sonographic findings for chronic lateral epicondylitis. (22764657)
2012
7
Pain management of chronic lateral epicondylitis: emerging new therapeutic options. (22494401)
2012
8
Effectiveness of initial extracorporeal shock wave therapy on the newly diagnosed lateral or medial epicondylitis. (23185733)
2012
9
Ultrasonographic detection of a metastatic elbow lesion mimicking epicondylitis. (21464675)
2011
10
Extracorporeal shock wave therapy for the treatment of lateral epicondylitis. (21210588)
2011
11
Clinical and ultrasonographic results of ultrasonographically guided percutaneous radiofrequency lesioning in the treatment of recalcitrant lateral epicondylitis. (21836121)
2011
12
Grip strength measurements at two different wrist extension positions in chronic lateral epicondylitis-comparison of involved vs. uninvolved side in athletes and non athletes: a case-control study. (20822520)
2010
13
A single botulinum toxin injection at a precise anatomic point on the forearm reduces pain at rest, compared to placebo injection in patients with chronic refractory lateral epicondylitis. (20699407)
2010
14
Effectiveness of corticosteroid injections compared with physiotherapeutic interventions for lateral epicondylitis: a systematic review. (19892089)
2009
15
Functional outcome of arthroscopic extensor carpi radialis brevis tendon release in chronic lateral epicondylitis. (19410988)
2009
16
Effectiveness of physical therapy treatments on lateral epicondylitis. (18515912)
2008
17
Early-stage tuberculous arthritis of the elbow presenting as lateral epicondylitis: diagnosis with sonography. (18204022)
2008
18
Anatomical study of arthroscopic surgery for lateral epicondylitis. (19054839)
2008
19
Conservative treatment of lateral epicondylitis: comparison of two different orthotic devices. (18365136)
2008
20
Decreased intramuscular blood flow in patients with lateral epicondylitis. (16805786)
2007
21
Effects of low-level laser and plyometric exercises in the treatment of lateral epicondylitis. (17603862)
2007
22
Short- and long-term improvement in lateral epicondylitis. (17993800)
2007
23
Comparison of effects of Cyriax physiotherapy, a supervised exercise programme and polarized polychromatic non-coherent light (Bioptron light) for the treatment of lateral epicondylitis. (16502745)
2006
24
Prevalence and determinants of lateral and medial epicondylitis: a population study. (16968862)
2006
25
Pulsed low-intensity ultrasound therapy for chronic lateral epicondylitis: a randomized controlled trial. (16303817)
2006
26
Treatment of lateral epicondylitis with botulinum toxin: a randomized, double-blind, placebo-controlled trial. (16330790)
2005
27
Anconeus muscle transposition for chronic lateral epicondylitis, recurrences, and complications. (16201252)
2005
28
Long-term effectiveness of extracorporeal shockwave therapy in the treatment of previously untreated lateral epicondylitis. (16162988)
2005
29
Lateral epicondylitis. (15474229)
2004
30
Cyriax physiotherapy for tennis elbow/lateral epicondylitis. (15562158)
2004
31
Litigants' epicondylitis. (12954257)
2003
32
Lateral epicondylitis of the elbow. (16518219)
2003
33
Interobserver reproducibility of the assessment of severity of complaints, grip strength, and pressure pain threshold in patients with lateral epicondylitis. (12161838)
2002
34
Comparison of sonography and MRI for diagnosing epicondylitis. (11981928)
2002
35
Chronic medial and lateral epicondylitis: a comparison of pain, disability, and function. (11887110)
2002
36
Surgical treatment of resistant lateral epicondylitis. Follow-up study of 19 patients after excision, release and repair of proximal common extensor tendon origin. (12483332)
2002
37
Low intensity Nd:YAG laser irradiation for lateral epicondylitis. (11871356)
2002
38
Conservative chiropractic care of lateral epicondylitis. (11145803)
2000
39
MR imaging findings of lateral ulnar collateral ligament abnormalities in patients with lateral epicondylitis. (10541124)
1999
40
Wrist extensor muscle pathology in lateral epicondylitis. (10372771)
1999
41
Bilateral epicondylitis in a karate instructor. (9832884)
1998
42
Ulnar nerve injury at the elbow after steroid injection for medial epicondylitis. (9061530)
1997
43
The efficacy of an injection of steroids for medial epicondylitis. A prospective study of sixty elbows. (9384424)
1997
44
Endoscopic therapy in epicondylitis radialis humeri. (8679041)
1995
45
Spray bottle epicondylitis. Diagnosing and treating workers in pain. (8130679)
1994
46
Lateral epicondylitis (tennis elbow): a review. (1490023)
1992
47
The surgical treatment of chronic lateral humeral epicondylitis by common extensor release. (3402125)
1988
48
Nerve conduction studies in lateral epicondylitis. (6697078)
1984
49
The etiology and treatment of epicondylitis. (5685146)
1968
50
Lateral epicondylitis of the elbow treated by fasciotomy. (13298976)
1956

Genetic Variations for Epicondylitis

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Expression for genes affiliated with Epicondylitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epicondylitis

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Pathways for genes affiliated with Epicondylitis

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Sources:
49PharmGKB, 53Reactome, 37NCBI BioSystems Database
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Pathways related to Epicondylitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8TH, CHAT
2
Hide members
9.8TH, CHAT
39.1TH, TAC1, CHAT

Compounds for genes affiliated with Epicondylitis

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Sources:
44Novoseek, 24HMDB, 28IUPHAR, 11DrugBank, 49PharmGKB, 2BitterDB, 59Tocris Bioscience
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Compounds related to Epicondylitis according to GeneCards/GeneDecks:

(show all 25)
idCompoundScoreTop Affiliating Genes
1ibotenic acid4410.1TH, CHAT
2homovanillic acid44 2411.1TH, CHAT
3l-amino acid4410.0TH, CHAT
4apomorphine44 28 1112.0TH, CHAT
5methamphetamine44 49 1112.0CHAT, TH
6scopolamine44 28 11 2412.8TAC1, CHAT
7amphetamine44 1110.7TH, TAC1
8mptp449.7TH, TAC1
9atropine44 28 1111.5TH, TAC1
106-hydroxydopamine449.5TH, TAC1, CHAT
11haloperidol44 28 2 49 1113.5CHAT, TAC1, TH
12kainate44 2810.5TH, TAC1, CHAT
13tetrodotoxin44 59 2811.5TH, TAC1
14sodium nitroprusside449.5TH, TAC1, CHAT
155-hydroxytryptamine449.5CHAT, TAC1, TH
16nicotine44 49 28 1112.5TH, TAC1, CHAT
17gaba449.4CHAT, TAC1, TH
18nmda44 2810.4CHAT, TAC1, TH
19norepinephrine44 11 2411.4TH, TAC1, CHAT
20opiate449.4TAC1, TH
21acetylcholine44 49 28 11 2413.4TH, TAC1, CHAT
22forskolin44 49 1111.3CHAT, TAC1, TH
23aspartate449.1TH, TAC1, CHAT
24dopamine44 28 11 2411.8TH, TAC1, CHAT
25glutamine448.8TH, TAC1, MED15

GO Terms for genes affiliated with Epicondylitis

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16Gene Ontology
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Biological processes related to Epicondylitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurotransmitter biosynthetic processGO:0421369.8TH, CHAT

Products for genes affiliated with Epicondylitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epicondylitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet