MCID: EPD015
MIFTS: 29

Epidemic Typhus malady

Infectious diseases, Rare diseases categories

Summaries for Epidemic Typhus

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Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A typhus that has material basis in rickettsia prowazekii, which is transmitted by human body louse (pediculus humanus corporis). the infection has symptom high fever, has symptom cough, has symptom rash, has symptom severe muscle pain, has symptom chills, has symptom falling blood pressure, has symptom stupor, has symptom sensitivity to light, and has symptom delirium.

MalaCards: Epidemic Typhus, also known as typhus, epidemic louse-borne, is related to typhus and brill-zinsser disease, and has symptoms including sensitivity to light, falling blood pressure and severe muscle pain. Affiliated tissues include bone.

Wikipedia:66 Epidemic typhus (also called \"camp fever\", \"jail fever\", \"hospital fever\", \"ship fever\",... more...

Aliases & Classifications for Epidemic Typhus

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9Disease Ontology, 50Orphanet, 63UMLS, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases, Rare diseases


Characteristics (Orphanet epidemiological data):

50
epidemic typhus:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Any age


Aliases & Descriptions:

epidemic typhus 9 50
typhus, epidemic louse-borne 63
sylvatic typhus 9


External Ids:

Disease Ontology9 DOID:0050480
MESH via Orphanet37 D014438
ICD10 via Orphanet27 A75.0
SNOMED-CT via Orphanet60 39111003
UMLS via Orphanet64 C0041473

Related Diseases for Epidemic Typhus

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Epidemic Typhus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1typhus11.1
2brill-zinsser disease10.4
3spotted fever10.4
4rocky mountain spotted fever10.3
5trench fever10.3
6relapsing fever10.3
7relapsing epidemic typhus10.3
8pediculus humanus corporis infestation10.1
9endemic typhus10.1
10q fever10.1
11louse-borne relapsing fever10.1
12dysentery10.1
13encephalitis10.1
14meningitis10.1
15bacteremia10.1

Graphical network of diseases related to Epidemic Typhus:



Diseases related to epidemic typhus

Symptoms for Epidemic Typhus

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9Disease Ontology
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Symptoms:

9 (show all 9)
  • sensitivity to light
  • falling blood pressure
  • severe muscle pain
  • delirium
  • rash
  • stupor
  • high fever
  • chills
  • cough

Drugs & Therapeutics for Epidemic Typhus

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Epidemic Typhus

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Anatomical Context for Epidemic Typhus

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34MalaCards
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MalaCards organs/tissues related to Epidemic Typhus:

34
Bone

Animal Models for Epidemic Typhus or affiliated genes

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Publications for Epidemic Typhus

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53PubMed
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Articles related to Epidemic Typhus:

(show top 50)    (show all 103)
idTitleAuthorsYear
1
Genome Sequencing of Four Strains of Rickettsia prowazekii, the Causative Agent of Epidemic Typhus, Including One Flying Squirrel Isolate. (23814035)
2013
2
Epidemic typhus. (18582834)
2008
3
Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus. (16145131)
2005
4
Autochthonous epidemic typhus associated with Bartonella quintana bacteremia in a homeless person. (15891141)
2005
5
The history of epidemic typhus. (15081509)
2004
6
Epidemic typhus meningitis in the southwestern United States. (11247722)
2001
7
Epidemic typhus imported from Algeria. (10511530)
1999
8
Imported epidemic typhus. (9853468)
1998
9
Outbreak of epidemic typhus in Russia. (9798622)
1998
10
Epidemic typhus risk in Rwandan refugee camps. (7947074)
1994
11
Flying squirrels and their ectoparasites: disseminators of epidemic typhus. (15462918)
1987
12
Flying squirrel-associated Rickettsia prowazekii (epidemic typhus rickettsiae) characterized by a specific DNA fragment produced by restriction endonuclease digestion. (3009528)
1986
13
Epidemic typhus acquired in Wisconsin. (3976245)
1985
14
Murine and epidemic typhus rickettsiae: how close is their relationship? (6817526)
1982
15
Epidemic typhus in the United States associated with flying squirrels. (6785459)
1981
16
Prescription and devotion: the Reverend Doctor Donne and the learned Doctor Mayerne--two seventeenth-century records of epidemic typhus fever. (362088)
1978
17
Serologic diagnosis of epidemic typhus fever. (403761)
1977
18
A reference, inactivated, epidemic typhus vaccine: clinical trials in man. (820697)
1976
19
John Donne's Devotions: an early record of epidemic typhus. (791999)
1976
20
Epidemic typhus rickettsiae isolated from flying squirrels. (806809)
1975
21
Single-dose doxycycline treatment of louse-borne relapsing fever and epidemic typhus. (4143011)
1974
22
Treatment of epidemic typhus. A comparative study of chloramphenicol, trimethoprim-sulphamethoxazole and doxycycline. (4591783)
1973
23
Evidence for extra-human epidemic typhus in the wild animals of Egypt. (5752388)
1968
24
Epidemic typhus and other rickettsioses in domestic animals and their ticks. (5752745)
1968
25
Inactivated epidemic typhus vaccine. Requirements for primary sensitization and booster response in man. (6081381)
1967
26
Serologic response in man to varying amounts of inactivated epidemic typhus vaccine. (15938324)
1967
27
SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). I. DIFFERENCES IN COMPLEMENT-FIXING ANTIBODIES: HIGH ANTIGEN REQUIREMENT AND HEAT LABILITY. (14296293)
1965
28
SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). II. DIFFERENCES IN IMMUNOELECTROPHORETIC PATTERNS, RESPONSE TO 2-MERCAPTOETHANOL AND RELATIONSHIPS TO 19 S AND 7 S ANTIBODIES. (14296294)
1965
29
Determination of serological immunity to epidemic typhus by response to vaccine. (13727014)
1961
30
The specificity of antibody response in typhus fever. Its alteration during murine typhus infection as a result of previous exposure to epidemic typhus antigen. (13848369)
1959
31
Brill's disease (recrudescent epidemic typhus) in Australia. (13838802)
1959
32
Immunization against epidemic typhus; a brief general review and a description of the status of living, avirulent R. prowazeki (strain E) as an immunizing agent. (13327181)
1956
33
The therapy of epidemic typhus with the newer antibiotics. (13295774)
1955
34
The incidence of epidemic typhus antibodies in individuals born in Eastern Europe. (14377231)
1955
35
Infection of man with avirulent rickettsiae of epidemic typhus (strain E). (13124325)
1954
36
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki (strain E); observations as to post-vaccination reactions, the relation of serologic response to size and route of infecting dose, and the resistance to challenge with virulent typhus strains. (13124326)
1954
37
PATHOLOGY of epidemic typhus; report of fatal cases studied by United States of America Typhus Commission in Cairo, Egypt, during 1943-1945. (13091587)
1953
38
Survey of epidemic typhus antibody levels in bloods of individuals born in Eastern and Central Europe and the United States. (14914753)
1952
39
Simultaneous cultivation of epidemic typhus rickettsia and Japanese B encephalitis virus in the developing chick embryos. (14928403)
1952
40
Antibody response of human subjects to epidemic typhus vaccine three to eight years after previous immunization. (14927925)
1952
41
Brill's diseases; recrudescent epidemic typhus fever; its occurrence in South Africa. (12984187)
1952
42
Treatment of endemic and epidemic typhus with antibiotics. (13139178)
1952
43
Epidemic typhus vaccine; antibody response to a single dose among persons previously vaccinated. (14867044)
1951
44
Studies on commercial typhus vaccines. I. The antigenic constituents of commercial epidemic typhus vaccine. (14794908)
1950
45
Aureomycin therapy of recrudescent epidemic typhus. (18123175)
1949
46
The relative infectibility of laboratory animals and chick embryos with rickettsiae of murine or of epidemic typhus. (18121211)
1949
47
Epidemic typhus in Garhwal district. (20266956)
1947
48
Diagnostic antigens for epidemic typhus, murine typhus and Rocky Mountain spotted fever. (20261082)
1947
49
Serologic studies in typhus-vaccinated individuals; Weil-Felix and complement-fixation findings in epidemic typhus fever occurring in the vaccinated. (20985787)
1946
50
TYPHUS FEVER AMONG RECENT IMMIGRANTS : EXPERIMENTAL DEMONSTRATION OF THE IDENTITY OF THIS DISEASE WITH EUROPEAN EPIDEMIC TYPHUS FEVER. (19868563)
1921

Variations for Epidemic Typhus

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Expression for genes affiliated with Epidemic Typhus

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16Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Epidemic Typhus.

Pathways for genes affiliated with Epidemic Typhus

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Compounds for genes affiliated with Epidemic Typhus

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GO Terms for genes affiliated with Epidemic Typhus

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Products for genes affiliated with Epidemic Typhus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidemic Typhus

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet