MCID: EPD015
MIFTS: 29

Epidemic Typhus malady

Infectious diseases category

Summaries for Epidemic Typhus

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A typhus that has material basis in rickettsia prowazekii, which is transmitted by human body louse (pediculus humanus corporis). the infection has symptom high fever, has symptom cough, has symptom rash, has symptom severe muscle pain, has symptom chills, has symptom falling blood pressure, has symptom stupor, has symptom sensitivity to light, and has symptom delirium.

MalaCards: Epidemic Typhus, also known as typhus, epidemic louse-borne, is related to typhus and brill-zinsser disease, and has symptoms including delirium, sensitivity to light and stupor. An important gene associated with Epidemic Typhus is GPT (glutamic-pyruvate transaminase (alanine aminotransferase)). Affiliated tissues include bone.

Wikipedia:63 Epidemic typhus (also called \"camp fever\", \"jail fever\", \"hospital fever\", \"ship fever\",... more...

Aliases & Classifications for Epidemic Typhus

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Sources:
8Disease Ontology, 48Orphanet, 60UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
epidemic typhus:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Any age


Aliases & Descriptions:

epidemic typhus 8 48
typhus, epidemic louse-borne 60
sylvatic typhus 8


External Ids:

Disease Ontology8 DOID:0050480
MESH via Orphanet35 D014438
ICD10 via Orphanet26 A75.0
SNOMED-CT via Orphanet57 39111003
UMLS via Orphanet61 C0041473

Related Diseases for Epidemic Typhus

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Epidemic Typhus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1typhus11.1
2brill-zinsser disease10.4
3spotted fever10.3
4endemic typhus10.2
5trench fever10.2
6rocky mountain spotted fever10.2
7relapsing fever10.2
8relapsing epidemic typhus10.2
9pediculus humanus corporis infestation10.1
10louse-borne relapsing fever10.1
11q fever10.1
12japanese encephalitis10.1
13dysentery10.1
14encephalitis10.1
15meningitis10.1

Graphical network of diseases related to Epidemic Typhus:



Diseases related to epidemic typhus

Clinical Features for Epidemic Typhus

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8Disease Ontology
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Symptoms:

8 (show all 9)
  • delirium
  • sensitivity to light
  • stupor
  • falling blood pressure
  • chills
  • severe muscle pain
  • rash
  • cough
  • high fever

Drugs & Therapeutics for Epidemic Typhus

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Epidemic Typhus

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Genetic Tests for Epidemic Typhus

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Anatomical Context for Epidemic Typhus

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Sources:
32MalaCards
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MalaCards organs/tissues related to Epidemic Typhus:

32
Bone

Animal Models for Epidemic Typhus or affiliated genes

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Publications for Epidemic Typhus

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Sources:
50PubMed
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Articles related to Epidemic Typhus:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Genome Sequencing of Four Strains of Rickettsia prowazekii, the Causative Agent of Epidemic Typhus, Including One Flying Squirrel Isolate. (23814035)
2013
2
Typhus syncopalis: an epidemic in Connecticut in 1823. (23155676)
2012
3
Cluster of sylvatic epidemic typhus cases associated with flying squirrels, 2004-2006. (19624912)
2009
4
Epidemic typhus. (18582834)
2008
5
Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China. (18541778)
2008
6
A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. (17537665)
2007
7
Autochthonous epidemic typhus associated with Bartonella quintana bacteremia in a homeless person. (15891141)
2005
8
Epidemic typhus meningitis in the southwestern United States. (11247722)
2001
9
Imported epidemic typhus. (9853468)
1998
10
Outbreak of epidemic typhus associated with trench fever in Burundi. (9717922)
1998
11
Jail fever (epidemic typhus) outbreak in Burundi. (9284381)
1997
12
Epidemic typhus in a prison in Burundi. (9196749)
1997
13
How Charles Nicolle of the Pasteur Institute discovered that epidemic typhus is transmitted by lice: reminiscences from my years at the Pasteur Institute in Paris. (8855211)
1996
14
Epidemic typhus risk in Rwandan refugee camps. (7947074)
1994
15
Epidemic typhus fever and hearing loss: a histological study (Hallpike collection of temporal bone sections). (8320509)
1993
16
Epidemic typhus--Georgia. (6436662)
1984
17
Epidemic typhus in the United States associated with flying squirrels. (6785459)
1981
18
Suspected Rocky Mountain spotted fever in the winter--epidemic typhus? (7312012)
1981
19
Epidemic typhus infection in cynomolgus monkeys (Macaca fascicularis). (7439974)
1980
20
Serologic diagnosis of epidemic typhus fever. (403761)
1977
21
Treatment of epidemic typhus. A comparative study of chloramphenicol, trimethoprim-sulphamethoxazole and doxycycline. (4591783)
1973
22
A search for the epidemic typhus agent in Ethiopian ticks. (4204491)
1973
23
Evidence for extra-human epidemic typhus in the wild animals of Egypt. (5752388)
1968
24
Serologic response in man to varying amounts of inactivated epidemic typhus vaccine. (15938324)
1967
25
Inactivated epidemic typhus vaccine. Observations on potency assay methods. (6083233)
1967
26
SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). II. DIFFERENCES IN IMMUNOELECTROPHORETIC PATTERNS, RESPONSE TO 2-MERCAPTOETHANOL AND RELATIONSHIPS TO 19 S AND 7 S ANTIBODIES. (14296294)
1965
27
Outbreak of epidemic typhus in the northern region of Saudi Arabia. (13933690)
1963
28
The specificity of antibody response in typhus fever. Its alteration during murine typhus infection as a result of previous exposure to epidemic typhus antigen. (13848369)
1959
29
Fluorescent antibody methods in the differentiation of murine and epidemic typhus sera; specificity changes resulting from previous immunization. (13641671)
1959
30
Ecologic studies on the interepidemic survival of louse-borne epidemic typhus fever. (13520704)
1958
31
The incidence of epidemic typhus antibodies in individuals born in Eastern Europe. (14377231)
1955
32
Studies on the interepidemic survival of louse borne epidemic typhus fever. (13233179)
1955
33
Infection of man with avirulent rickettsiae of epidemic typhus (strain E). (13124325)
1954
34
Quantitative comparison of responses of cotton rats and albino mice to measured doses of epidemic typhus rickettsiae. (13201754)
1954
35
PATHOLOGY of epidemic typhus; report of fatal cases studied by United States of America Typhus Commission in Cairo, Egypt, during 1943-1945. (13091587)
1953
36
Studies of human body lice Pediculus humanus corporis. II. Quantitative comparisons of the susceptibility of human body lice and cotton rats to experimental infection with epidemic typhus rickettsiae. (13080260)
1953
37
Antibody response of human subjects to epidemic typhus vaccine three to eight years after previous immunization. (14927925)
1952
38
Epidemic typhus vaccine; antibody response to a single dose among persons previously vaccinated. (14867044)
1951
39
Typhus at Belsen. II. Clinical course of epidemic typhus in persons who had received Craigie typhus vaccine. (14800216)
1951
40
Terramycin in epidemic typhus, amebic dysentery, and typhoid. (14880440)
1951
41
Studies on commercial typhus vaccines. I. The antigenic constituents of commercial epidemic typhus vaccine. (14794908)
1950
42
Studies on commercial typhus vaccines. II. The antigenic fractions of disrupted epidemic typhus rickettsiae. (14794909)
1950
43
Epidemic typhus in southwestern Arabia. (18145866)
1949
44
Treatment of epidemic typhus with chloromycetin. (18912182)
1948
45
Epidemic typhus in Garhwal district. (20266956)
1947
46
Serologic studies in typhus-vaccinated individuals; Weil-Felix and complement-fixation findings in epidemic typhus fever occurring in the vaccinated. (20985787)
1946
47
A method for increasing the infectivity of yolk-sac cultures of the rickettsiae of epidemic and murine typhus, and South African tick-bite fever. (20282007)
1946
48
Serological relationships in the epidemic-endemic typhus group as determined by complement fixation. (21065206)
1946
49
The Antibody Response of Guinea Pigs to Epidemic Typhus Vaccines of Various Antigenicities. (16560995)
1945
50
The Serbian Epidemics of Typhus and Relapsing Fever in 1915: Their Origin, Course, and Preventive Measures employed for their Arrest : (An A8tiological and Preventive Study based on Records of British Military Sanitary Mission to Serbia, 1915.). (20905688)
1920

Genetic Variations for Epidemic Typhus

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Expression for genes affiliated with Epidemic Typhus

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidemic Typhus

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Pathways for genes affiliated with Epidemic Typhus

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Compounds for genes affiliated with Epidemic Typhus

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GO Terms for genes affiliated with Epidemic Typhus

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Products for genes affiliated with Epidemic Typhus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidemic Typhus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet