MCID: EPD015
MIFTS: 29

Epidemic Typhus malady

Infectious diseases category

Summaries for Epidemic Typhus

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A typhus that has material basis in rickettsia prowazekii, which is transmitted by human body louse (pediculus humanus corporis). the infection has symptom high fever, has symptom cough, has symptom rash, has symptom severe muscle pain, has symptom chills, has symptom falling blood pressure, has symptom stupor, has symptom sensitivity to light, and has symptom delirium.

MalaCards: Epidemic Typhus, also known as typhus, epidemic louse-borne, is related to typhus and brill-zinsser disease, and has symptoms including delirium, sensitivity to light and stupor. An important gene associated with Epidemic Typhus is GPT (glutamic-pyruvate transaminase (alanine aminotransferase)). Affiliated tissues include bone.

Wikipedia:63 Epidemic typhus (also called \"camp fever\", \"jail fever\", \"hospital fever\", \"ship fever\",... more...

Aliases & Classifications for Epidemic Typhus

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Sources:
8Disease Ontology, 48Orphanet, 60UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
epidemic typhus:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Any age


Aliases & Descriptions:

epidemic typhus 8 48
typhus, epidemic louse-borne 60
sylvatic typhus 8


External Ids:

Disease Ontology8 DOID:0050480
MESH via Orphanet35 D014438
ICD10 via Orphanet26 A75.0
SNOMED-CT via Orphanet57 39111003
UMLS via Orphanet61 C0041473

Related Diseases for Epidemic Typhus

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Epidemic Typhus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1typhus11.1
2brill-zinsser disease10.4
3spotted fever10.3
4endemic typhus10.2
5trench fever10.2
6rocky mountain spotted fever10.2
7relapsing fever10.2
8relapsing epidemic typhus10.2
9pediculus humanus corporis infestation10.1
10louse-borne relapsing fever10.1
11q fever10.1
12japanese encephalitis10.1
13dysentery10.1
14encephalitis10.1
15meningitis10.1

Graphical network of diseases related to Epidemic Typhus:



Diseases related to epidemic typhus

Clinical Features for Epidemic Typhus

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8Disease Ontology
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Symptoms:

8 (show all 9)
  • delirium
  • sensitivity to light
  • stupor
  • falling blood pressure
  • chills
  • severe muscle pain
  • rash
  • cough
  • high fever

Drugs & Therapeutics for Epidemic Typhus

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Epidemic Typhus

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Anatomical Context for Epidemic Typhus

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32MalaCards
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MalaCards organs/tissues related to Epidemic Typhus:

32
Bone

Animal Models for Epidemic Typhus or affiliated genes

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Publications for Epidemic Typhus

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Sources:
50PubMed
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Articles related to Epidemic Typhus:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Genome Sequencing of Four Strains of Rickettsia prowazekii, the Causative Agent of Epidemic Typhus, Including One Flying Squirrel Isolate. (23814035)
2013
2
Environmental risk factors for epidemic typhus in the United States: wintertime is typhus time. (22533108)
2012
3
Brill-Zinsser disease in a patient following infection with sylvatic epidemic typhus associated with flying squirrels. (20687836)
2010
4
A community-based case-control study of behavioral factors associated with scrub typhus during the autumn epidemic season in South Korea. (19270296)
2009
5
Epidemic typhus. (18582834)
2008
6
Follow-up analysis on the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, China. (17877223)
2007
7
Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China. (17711736)
2007
8
A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. (17537665)
2007
9
Autochthonous epidemic typhus associated with Bartonella quintana bacteremia in a homeless person. (15891141)
2005
10
Reemerging threat of epidemic typhus in Algeria. (15297561)
2004
11
Serological differentiation of murine typhus and epidemic typhus using cross-adsorption and Western blotting. (10882661)
2000
12
Imported epidemic typhus. (9853468)
1998
13
Outbreak of epidemic typhus associated with trench fever in Burundi. (9717922)
1998
14
Jail fever (epidemic typhus) outbreak in Burundi. (9284381)
1997
15
Epidemic typhus in a prison in Burundi. (9196749)
1997
16
Epidemic typhus risk in Rwandan refugee camps. (7947074)
1994
17
Epidemic typhus fever and hearing loss: a histological study (Hallpike collection of temporal bone sections). (8320509)
1993
18
Flying squirrels and their ectoparasites: disseminators of epidemic typhus. (15462918)
1987
19
Flying squirrel-associated Rickettsia prowazekii (epidemic typhus rickettsiae) characterized by a specific DNA fragment produced by restriction endonuclease digestion. (3009528)
1986
20
Detection and characterization of mouse monoclonal antibodies to epidemic typhus rickettsiae. (6415092)
1983
21
Epidemic typhus infection in cynomolgus monkeys (Macaca fascicularis). (7439974)
1980
22
Forecasting the onset of a scrub typhus epidemic in the Pescadores Islands of Taiwan using daily maximum temperatures. (542987)
1979
23
Prescription and devotion: the Reverend Doctor Donne and the learned Doctor Mayerne--two seventeenth-century records of epidemic typhus fever. (362088)
1978
24
Single-dose doxycycline treatment of louse-borne relapsing fever and epidemic typhus. (4143011)
1974
25
A search for the epidemic typhus agent in Ethiopian ticks. (4204491)
1973
26
Evidence for extra-human epidemic typhus in the wild animals of Egypt. (5752388)
1968
27
Domestic animals and their role in epidemic typhus. (5736440)
1968
28
Serologic response in man to varying amounts of inactivated epidemic typhus vaccine. (15938324)
1967
29
EPIDEMIC TYPHUS FEVER AND HISTORY. (14298162)
1965
30
Outbreak of epidemic typhus in the northern region of Saudi Arabia. (13933690)
1963
31
Determination of serological immunity to epidemic typhus by response to vaccine. (13727014)
1961
32
The specificity of antibody response in typhus fever. Its alteration during murine typhus infection as a result of previous exposure to epidemic typhus antigen. (13848369)
1959
33
Brill's disease (recrudescent epidemic typhus) in Australia. (13838802)
1959
34
An evaluation of tetracycline-oleandomycin in the treatment of epidemic typhus. (13637752)
1958-1959
35
A review of experience with an avirulent strain of R. prowazeki (strain E) as a living agent for immunizing man against epidemic typhus. (13238649)
1955
36
Studies on the interepidemic survival of louse borne epidemic typhus fever. (13233179)
1955
37
Infection of man with avirulent rickettsiae of epidemic typhus (strain E). (13124325)
1954
38
Studies of human body lice Pediculus humanus corporis. II. Quantitative comparisons of the susceptibility of human body lice and cotton rats to experimental infection with epidemic typhus rickettsiae. (13080260)
1953
39
Antibody response of human subjects to epidemic typhus vaccine three to eight years after previous immunization. (14927925)
1952
40
Epidemic typhus vaccine; antibody response to a single dose among persons previously vaccinated. (14867044)
1951
41
Terramycin in epidemic typhus, amebic dysentery, and typhoid. (14880440)
1951
42
Studies on commercial typhus vaccines. I. The antigenic constituents of commercial epidemic typhus vaccine. (14794908)
1950
43
Aureomycin therapy of recrudescent epidemic typhus. (18123175)
1949
44
Treatment of epidemic typhus with chloromycetin. (18912182)
1948
45
Serologic studies in typhus-vaccinated individuals; Weil-Felix and complement-fixation findings in epidemic typhus fever occurring in the vaccinated. (20985787)
1946
46
A method for increasing the infectivity of yolk-sac cultures of the rickettsiae of epidemic and murine typhus, and South African tick-bite fever. (20282007)
1946
47
Serological relationships in the epidemic-endemic typhus group as determined by complement fixation. (21065206)
1946
48
The Antibody Response of Guinea Pigs to Epidemic Typhus Vaccines of Various Antigenicities. (16560995)
1945
49
TYPHUS FEVER AMONG RECENT IMMIGRANTS : EXPERIMENTAL DEMONSTRATION OF THE IDENTITY OF THIS DISEASE WITH EUROPEAN EPIDEMIC TYPHUS FEVER. (19868563)
1921
50
The Serbian Epidemics of Typhus and Relapsing Fever in 1915: Their Origin, Course, and Preventive Measures employed for their Arrest : (An A8tiological and Preventive Study based on Records of British Military Sanitary Mission to Serbia, 1915.). (20905688)
1920

Genetic Variations for Epidemic Typhus

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Expression for genes affiliated with Epidemic Typhus

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidemic Typhus

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Pathways for genes affiliated with Epidemic Typhus

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Compounds for genes affiliated with Epidemic Typhus

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GO Terms for genes affiliated with Epidemic Typhus

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Products for genes affiliated with Epidemic Typhus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidemic Typhus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet