MCID: EPD015
MIFTS: 26

Epidemic Typhus malady

Infectious category

Summaries for Epidemic Typhus

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A typhus that has material basis in rickettsia prowazekii, which is transmitted by human body louse (pediculus humanus corporis). the infection has symptom high fever, has symptom cough, has symptom rash, has symptom severe muscle pain, has symptom chills, has symptom falling blood pressure, has symptom stupor, has symptom sensitivity to light, and has symptom delirium.

MalaCards: Epidemic Typhus, also known as typhus, epidemic louse-borne, is related to typhus and brill-zinsser disease, and has symptoms including cough, chills and rash. An important gene associated with Epidemic Typhus is GPT (glutamic-pyruvate transaminase (alanine aminotransferase)).

Wikipedia:64 Epidemic typhus (also called \"camp fever\", \"jail fever\", \"hospital fever\", \"ship fever\",... more...

Aliases & Classifications for Epidemic Typhus

Sources:
8Disease Ontology, 49Orphanet, 61UMLS, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Characteristics (Orphanet epidemiological data):

49
epidemic typhus:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Any age


Aliases & Descriptions:

epidemic typhus 8 49
typhus, epidemic louse-borne 61
sylvatic typhus 8


External Ids:

Disease Ontology8 DOID:0050480
MESH via Orphanet36 D014438
ICD10 via Orphanet26 A75.0
SNOMED-CT via Orphanet58 39111003
UMLS via Orphanet62 C0041473

Related Diseases for Epidemic Typhus

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Epidemic Typhus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1typhus11.1
2brill-zinsser disease10.4
3relapsing epidemic typhus10.4
4spotted fever10.4
5endemic typhus10.3
6trench fever10.3
7rocky mountain spotted fever10.3
8pediculus humanus corporis infestation10.1
9louse-borne relapsing fever10.1
10japanese encephalitis10.1
11bacteremia10.1

Graphical network of diseases related to Epidemic Typhus:



Diseases related to epidemic typhus

Clinical Features for Epidemic Typhus

Sources:
8Disease Ontology
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Symptoms:

8 (show all 9)
  • cough
  • chills
  • rash
  • delirium
  • high fever
  • stupor
  • severe muscle pain
  • falling blood pressure
  • sensitivity to light

Drugs & Therapeutics for Epidemic Typhus

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Epidemic Typhus

Drug clinical trials:

Search ClinicalTrials for Epidemic Typhus

Search NIH Clinical Center for Epidemic Typhus

Search CenterWatch for Epidemic Typhus

Genetic Tests for Epidemic Typhus

Anatomical Context for Epidemic Typhus

Animal Models for Epidemic Typhus or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Epidemic Typhus

Sources:
51PubMed
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Articles related to Epidemic Typhus:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Typhus syncopalis: an epidemic in Connecticut in 1823. (23155676)
2012
2
Report on the typhus epidemic in Upper Silesia. 1848. (17123938)
2006
3
Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus. (16145131)
2005
4
The history of epidemic typhus. (15081509)
2004
5
Jakub Penson and his studies on acute renal failure during typhus epidemics in Warsaw Ghetto. (15151276)
2004
6
Epidemic typhus meningitis in the southwestern United States. (11247722)
2001
7
Epidemic typhus imported from Algeria. (10511530)
1999
8
Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever. (10476755)
1999
9
Outbreak of epidemic typhus in Russia. (9798622)
1998
10
A clinico-epidemiological study of epidemic typhus in Africa. (1600020)
1992
11
Cardiovascular and pulmonary complications of epidemic typhus. (2763350)
1989
12
Rickettsial vaccines with emphasis on epidemic typhus. Initial report of an old vaccine trial. (3095934)
1986
13
Epidemic typhus acquired in Wisconsin. (3976245)
1985
14
Epidemic typhus--Georgia. (6436662)
1984
15
Murine and epidemic typhus rickettsiae: how close is their relationship? (6817526)
1982
16
Epidemic typhus associated with flying squirrels--United States. (6817059)
1982
17
Epidemic typhus in the United States associated with flying squirrels. (6785459)
1981
18
Indigenous acquisition of epidemic typhus in the eastern United States. (6781073)
1981
19
Epidemic typhus (Rickettsia prowazekii) in Massachusetts: evidence of infection. (6783902)
1981
20
Epizootiology of epidemic typhus (Rickettsia prowazekii) in flying squirrels. (646026)
1978
21
A reference, inactivated, epidemic typhus vaccine: clinical trials in man. (820697)
1976
22
John Donne's Devotions: an early record of epidemic typhus. (791999)
1976
23
Epidemic typhus rickettsiae isolated from flying squirrels. (806809)
1975
24
Treatment of epidemic typhus. A comparative study of chloramphenicol, trimethoprim-sulphamethoxazole and doxycycline. (4591783)
1973
25
Single-dose treatment of epidemic typhus with doxycyline. (4580526)
1973
26
Epidemic typhus and other rickettsioses in domestic animals and their ticks. (5752745)
1968
27
Inactivated epidemic typhus vaccine. Requirements for primary sensitization and booster response in man. (6081381)
1967
28
Electroencephalographic pattern in epidemic typhus. (4165016)
1967
29
Combined epidemic typhus and Q-fever vaccine: adjuvant effect of Coxiella burneti. (6042428)
1967
30
SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). I. DIFFERENCES IN COMPLEMENT-FIXING ANTIBODIES: HIGH ANTIGEN REQUIREMENT AND HEAT LABILITY. (14296293)
1965
31
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki strain E. IV. Persistence of immunity and a note as to differing complement-fixation antigen requirements in post-infection and post-vaccination sera. (13481387)
1957
32
Immunization against epidemic typhus; a brief general review and a description of the status of living, avirulent R. prowazeki (strain E) as an immunizing agent. (13327181)
1956
33
The therapy of epidemic typhus with the newer antibiotics. (13295774)
1955
34
A survey of sero-immunity against epidemic typhus among certain population groups in Peru. (13268416)
1955
35
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki (strain E); observations as to post-vaccination reactions, the relation of serologic response to size and route of infecting dose, and the resistance to challenge with virulent typhus strains. (13124326)
1954
36
Quantitative comparison of responses of cotton rats and albino mice to measured doses of epidemic typhus rickettsiae. (13201754)
1954
37
PATHOLOGY of epidemic typhus; report of fatal cases studied by United States of America Typhus Commission in Cairo, Egypt, during 1943-1945. (13091597)
1953
38
Survey of epidemic typhus antibody levels in bloods of individuals born in Eastern and Central Europe and the United States. (14914753)
1952
39
Simultaneous cultivation of epidemic typhus rickettsia and Japanese B encephalitis virus in the developing chick embryos. (14928403)
1952
40
Brill's diseases; recrudescent epidemic typhus fever; its occurrence in South Africa. (12984187)
1952
41
Treatment of endemic and epidemic typhus with antibiotics. (13139178)
1952
42
Epidemic-typhus antibodies in human subjects in Boston, Massachusetts. (14899644)
1952
43
Studies on commercial typhus vaccines. II. The antigenic fractions of disrupted epidemic typhus rickettsiae. (14794909)
1950
44
The relative infectibility of laboratory animals and chick embryos with rickettsiae of murine or of epidemic typhus. (18121211)
1949
45
Aureomycin, a new antibiotic with antirickettsial properties; its effect on experimental spotted fever and epidemic typhus. (18112236)
1948
46
EPIDEMIC typhus fever. (18863132)
1948
47
Epidemic typhus in Garhwal district. (20266956)
1947
48
Diagnostic antigens for epidemic typhus, murine typhus and Rocky Mountain spotted fever. (20261082)
1947
49
The constitution of that rickettsia and soluble rickettsial antigen derived from the epidemic typhus vaccine. (21066650)
1946
50
The antibody response of guinea pigs to epidemic typhus vaccines of various antigenicities. (21005558)
1945

Genetic Variations for Epidemic Typhus

Expression for genes affiliated with Epidemic Typhus

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidemic Typhus

Search GEO for disease gene expression data for Epidemic Typhus.

Pathways for genes affiliated with Epidemic Typhus

Compounds for genes affiliated with Epidemic Typhus

GO Terms for genes affiliated with Epidemic Typhus

Products for genes affiliated with Epidemic Typhus

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidemic Typhus

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet