MCID: EPD015
MIFTS: 29

Epidemic Typhus malady

Infectious diseases category

Summaries for Epidemic Typhus

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A typhus that has material basis in rickettsia prowazekii, which is transmitted by human body louse (pediculus humanus corporis). the infection has symptom high fever, has symptom cough, has symptom rash, has symptom severe muscle pain, has symptom chills, has symptom falling blood pressure, has symptom stupor, has symptom sensitivity to light, and has symptom delirium.

MalaCards: Epidemic Typhus, also known as typhus, epidemic louse-borne, is related to typhus and brill-zinsser disease, and has symptoms including sensitivity to light, falling blood pressure and severe muscle pain. An important gene associated with Epidemic Typhus is GPT (glutamic-pyruvate transaminase (alanine aminotransferase)). Affiliated tissues include bone.

Wikipedia:63 Epidemic typhus (also called \"camp fever\", \"jail fever\", \"hospital fever\", \"ship fever\",... more...

Aliases & Classifications for Epidemic Typhus

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Sources:
8Disease Ontology, 48Orphanet, 60UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Characteristics (Orphanet epidemiological data):

48
epidemic typhus:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Any age


Aliases & Descriptions:

epidemic typhus 8 48
typhus, epidemic louse-borne 60
sylvatic typhus 8


External Ids:

Disease Ontology8 DOID:0050480
MESH via Orphanet35 D014438
ICD10 via Orphanet26 A75.0
SNOMED-CT via Orphanet57 39111003
UMLS via Orphanet61 C0041473

Related Diseases for Epidemic Typhus

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Epidemic Typhus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1typhus11.1
2brill-zinsser disease10.4
3spotted fever10.3
4endemic typhus10.2
5trench fever10.2
6rocky mountain spotted fever10.2
7relapsing fever10.2
8relapsing epidemic typhus10.2
9pediculus humanus corporis infestation10.1
10louse-borne relapsing fever10.1
11q fever10.1
12japanese encephalitis10.1
13dysentery10.1
14encephalitis10.1
15meningitis10.1

Graphical network of diseases related to Epidemic Typhus:



Diseases related to epidemic typhus

Clinical Features for Epidemic Typhus

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8Disease Ontology
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Symptoms:

8 (show all 9)
  • sensitivity to light
  • falling blood pressure
  • severe muscle pain
  • stupor
  • high fever
  • delirium
  • rash
  • chills
  • cough

Drugs & Therapeutics for Epidemic Typhus

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Epidemic Typhus

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Genetic Tests for Epidemic Typhus

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Anatomical Context for Epidemic Typhus

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Sources:
32MalaCards
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MalaCards organs/tissues related to Epidemic Typhus:

32
Bone

Animal Models for Epidemic Typhus or affiliated genes

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Publications for Epidemic Typhus

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Sources:
50PubMed
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Articles related to Epidemic Typhus:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Typhus syncopalis: an epidemic in Connecticut in 1823. (23155676)
2012
2
Cluster of sylvatic epidemic typhus cases associated with flying squirrels, 2004-2006. (19624912)
2009
3
Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China. (18541778)
2008
4
Report on the typhus epidemic in Upper Silesia. 1848. (17123938)
2006
5
Jakub Penson and his studies on acute renal failure during typhus epidemics in Warsaw Ghetto. (15151276)
2004
6
Epidemic typhus meningitis in the southwestern United States. (11247722)
2001
7
Epidemic typhus imported from Algeria. (10511530)
1999
8
Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever. (10476755)
1999
9
Outbreak of epidemic typhus in Russia. (9798622)
1998
10
Epidemic typhus in a prison in Burundi. (9196749)
1997
11
How Charles Nicolle of the Pasteur Institute discovered that epidemic typhus is transmitted by lice: reminiscences from my years at the Pasteur Institute in Paris. (8855211)
1996
12
Cardiovascular and pulmonary complications of epidemic typhus. (2763350)
1989
13
Epidemic typhus--Georgia. (6436662)
1984
14
Epidemic typhus associated with flying squirrels--United States. (6817059)
1982
15
Epidemic typhus in the United States associated with flying squirrels. (6785459)
1981
16
Indigenous acquisition of epidemic typhus in the eastern United States. (6781073)
1981
17
Epidemic typhus (Rickettsia prowazekii) in Massachusetts: evidence of infection. (6783902)
1981
18
Suspected Rocky Mountain spotted fever in the winter--epidemic typhus? (7312012)
1981
19
Epizootiology of epidemic typhus (Rickettsia prowazekii) in flying squirrels. (646026)
1978
20
Serologic diagnosis of epidemic typhus fever. (403761)
1977
21
A reference, inactivated, epidemic typhus vaccine: clinical trials in man. (820697)
1976
22
John Donne's Devotions: an early record of epidemic typhus. (791999)
1976
23
Epidemic typhus rickettsiae isolated from flying squirrels. (806809)
1975
24
Treatment of epidemic typhus. A comparative study of chloramphenicol, trimethoprim-sulphamethoxazole and doxycycline. (4591783)
1973
25
Single-dose treatment of epidemic typhus with doxycyline. (4580526)
1973
26
Inactivated epidemic typhus vaccine. Requirements for primary sensitization and booster response in man. (6081381)
1967
27
Serologic response in man to varying amounts of inactivated epidemic typhus vaccine. (15938324)
1967
28
Electroencephalographic pattern in epidemic typhus. (4165016)
1967
29
Inactivated epidemic typhus vaccine. Observations on potency assay methods. (6083233)
1967
30
SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). II. DIFFERENCES IN IMMUNOELECTROPHORETIC PATTERNS, RESPONSE TO 2-MERCAPTOETHANOL AND RELATIONSHIPS TO 19 S AND 7 S ANTIBODIES. (14296294)
1965
31
Fluorescent antibody methods in the differentiation of murine and epidemic typhus sera; specificity changes resulting from previous immunization. (13641671)
1959
32
Ecologic studies on the interepidemic survival of louse-borne epidemic typhus fever. (13520704)
1958
33
Immunization against epidemic typhus; a brief general review and a description of the status of living, avirulent R. prowazeki (strain E) as an immunizing agent. (13327181)
1956
34
The incidence of epidemic typhus antibodies in individuals born in Eastern Europe. (14377231)
1955
35
Studies on the interepidemic survival of louse borne epidemic typhus fever. (13233179)
1955
36
Infection of man with avirulent rickettsiae of epidemic typhus (strain E). (13124325)
1954
37
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki (strain E); observations as to post-vaccination reactions, the relation of serologic response to size and route of infecting dose, and the resistance to challenge with virulent typhus strains. (13124326)
1954
38
Quantitative comparison of responses of cotton rats and albino mice to measured doses of epidemic typhus rickettsiae. (13201754)
1954
39
PATHOLOGY of epidemic typhus; report of fatal cases studied by United States of America Typhus Commission in Cairo, Egypt, during 1943-1945. (13091587)
1953
40
Studies of human body lice Pediculus humanus corporis. II. Quantitative comparisons of the susceptibility of human body lice and cotton rats to experimental infection with epidemic typhus rickettsiae. (13080260)
1953
41
Simultaneous cultivation of epidemic typhus rickettsia and Japanese B encephalitis virus in the developing chick embryos. (14928403)
1952
42
Antibody response of human subjects to epidemic typhus vaccine three to eight years after previous immunization. (14927925)
1952
43
Epidemic-typhus antibodies in human subjects in Boston, Massachusetts. (14899644)
1952
44
Typhus at Belsen. II. Clinical course of epidemic typhus in persons who had received Craigie typhus vaccine. (14800216)
1951
45
Studies on commercial typhus vaccines. I. The antigenic constituents of commercial epidemic typhus vaccine. (14794908)
1950
46
Studies on commercial typhus vaccines. II. The antigenic fractions of disrupted epidemic typhus rickettsiae. (14794909)
1950
47
Epidemic typhus in southwestern Arabia. (18145866)
1949
48
Epidemic typhus in Garhwal district. (20266956)
1947
49
The constitution of that rickettsia and soluble rickettsial antigen derived from the epidemic typhus vaccine. (21066650)
1946
50
The Antibody Response of Guinea Pigs to Epidemic Typhus Vaccines of Various Antigenicities. (16560995)
1945

Genetic Variations for Epidemic Typhus

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Expression for genes affiliated with Epidemic Typhus

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidemic Typhus

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Pathways for genes affiliated with Epidemic Typhus

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Compounds for genes affiliated with Epidemic Typhus

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GO Terms for genes affiliated with Epidemic Typhus

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Products for genes affiliated with Epidemic Typhus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidemic Typhus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet