MCID: EPD010
MIFTS: 18

Epidermal Appendage Tumor

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Epidermal Appendage Tumor

MalaCards integrated aliases for Epidermal Appendage Tumor:

Name: Epidermal Appendage Tumor 12 14
Neoplasm of Skin with Adnexal Differentiation 12 69
Neoplasm of the Skin Appendage 12
Skin Appendage Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2433
NCIt 46 C4463
SNOMED-CT 64 126489007 55681005
UMLS 69 C0345988

Summaries for Epidermal Appendage Tumor

MalaCards based summary : Epidermal Appendage Tumor, also known as neoplasm of skin with adnexal differentiation, is related to chronic salpingitis and spiradenoma. An important gene associated with Epidermal Appendage Tumor is CYLD (CYLD Lysine 63 Deubiquitinase). The drug Dermatologic Agents has been mentioned in the context of this disorder. Affiliated tissues include skin.

Related Diseases for Epidermal Appendage Tumor

Diseases related to Epidermal Appendage Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 chronic salpingitis 9.6 CLEC2A TP53
2 spiradenoma 9.6 CYLD TP53
3 integumentary system cancer 9.5 CLEC2A TP53
4 basal cell carcinoma 9.3 CYLD TP53

Symptoms & Phenotypes for Epidermal Appendage Tumor

Drugs & Therapeutics for Epidermal Appendage Tumor

Drugs for Epidermal Appendage Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Dermatologic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 French National Database of Rare Dermatological Cancers Recruiting NCT03210935
2 Extracolonic Findings on Computed Tomography (CT) Colonography Enrolling by invitation NCT01465425

Search NIH Clinical Center for Epidermal Appendage Tumor

Genetic Tests for Epidermal Appendage Tumor

Anatomical Context for Epidermal Appendage Tumor

MalaCards organs/tissues related to Epidermal Appendage Tumor:

38
Skin

Publications for Epidermal Appendage Tumor

Articles related to Epidermal Appendage Tumor:

# Title Authors Year
1
CYLD mutations in familial skin appendage tumours. ( 18234730 )
2008

Variations for Epidermal Appendage Tumor

Expression for Epidermal Appendage Tumor

Search GEO for disease gene expression data for Epidermal Appendage Tumor.

Pathways for Epidermal Appendage Tumor

GO Terms for Epidermal Appendage Tumor

Biological processes related to Epidermal Appendage Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein deubiquitination GO:0016579 8.62 CYLD TP53

Molecular functions related to Epidermal Appendage Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 8.62 CYLD TP53

Sources for Epidermal Appendage Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....