MCID: EPD001
MIFTS: 48

Epidermodysplasia Verruciformis malady

Categories: Genetic diseases, Rare diseases, Skin diseases, Blood diseases

Aliases & Classifications for Epidermodysplasia Verruciformis

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Sources:
50OMIM, 11Disease Ontology, 46NIH Rare Diseases, 23GeneTests, 13DISEASES, 52Orphanet, 68UniProtKB/Swiss-Prot, 25GTR, 12diseasecard, 48Novoseek, 37MeSH, 66UMLS, 38MESH via Orphanet, 67UMLS via Orphanet, 29ICD10 via Orphanet, 35MedGen, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Epidermodysplasia Verruciformis:

Name: Epidermodysplasia Verruciformis 50 11 46 23 13 52 68 25 12 48 37 66
Lutz-Lewandowsky Epidermodysplasia Verruciformis 46 52
 
Lewandowsky-Lutz Syndrome 46 52
Ev 68

Characteristics:

Orphanet epidemiological data:

52
epidermodysplasia verruciformis:
Inheritance: Autosomal recessive; Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

OMIM50 226400
Disease Ontology11 DOID:13777
MeSH37 D004819
Orphanet52 ORPHA302
SNOMED-CT60 19138001
MESH via Orphanet38 D004819
UMLS via Orphanet67 C0014522
ICD10 via Orphanet29 B07
MedGen35 C0014522

Summaries for Epidermodysplasia Verruciformis

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OMIM:50 Epidermodysplasia verruciformis (EV) is a rare genodermatosis associated with a high risk of skin cancer (Ramoz et al.,... (226400) more...

MalaCards based summary: Epidermodysplasia Verruciformis, also known as lutz-lewandowsky epidermodysplasia verruciformis, is related to t-cell immunodeficiency with epidermodysplasia verruciformis and acute diarrhea, and has symptoms including seborrheic dermatitis, pustule and skin ulcer. An important gene associated with Epidermodysplasia Verruciformis is TMC6 (Transmembrane Channel Like 6), and among its related pathways is Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include skin, skin and t cells.

Disease Ontology:11 An autosomal recessive disease that results in skin squamous cell carcinoma located in skin, associated with a high risk of carcinoma. it is characterized by abnormal susceptibility to human papillomaviruses of the skin and has symptom lesions on the body.

UniProtKB/Swiss-Prot:68 Epidermodysplasia verruciformis: Rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions.

Wikipedia:69 Epidermodysplasia verruciformis (EV, also called Lewandowsky-Lutz dysplasia), colloquially known as tree... more...

Related Diseases for Epidermodysplasia Verruciformis

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Diseases related to Epidermodysplasia Verruciformis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1t-cell immunodeficiency with epidermodysplasia verruciformis12.2
2acute diarrhea10.6TMC6, TMC8
3leishmaniasis10.6TMC6, TMC8
4papilloma10.5
5keratosis10.4
6lymphoma10.4
7ichthyosis histrix, curth-macklin type10.3KRT10, KRT16
8craniodiaphyseal dysplasia, autosomal dominant10.3KRT10, KRT16
9systemic lupus erythematosus10.3
10melanoma10.3
11merkel cell carcinoma10.3
12lupus erythematosus10.3
13psoriasis10.3
14lipomatosis10.3KRT10, KRT16
15bullous keratopathy10.2KRT10, KRT16
16leprosy10.2
17lung sarcoma10.2IL10, KRT16
18distal arthrogryposis10.2KRT10, KRT16
19subacute monocytic leukemia10.1KRT10, KRT16
20common variable immunodeficiency10.1
21hepatitis10.1
22hepatitis b10.1
23leukemia10.1
24tuberculoid leprosy10.1
25acanthoma10.1
26cervicitis10.1
27rhabdomyosarcoma10.1
28molluscum contagiosum10.1
29lissencephaly10.1KRT10, KRT16
3012p12.1 microdeletion syndrome10.0CDH1, IL10
31ichthyosis, cyclic, with epidermolytic hyperkeratosis10.0KRT10, KRT16
32epidermolysis bullosa simplex, dowling-meara type10.0KRT10, KRT16, KRT4
33hypertrophic or verrucous lupus erythematosus10.0IL10, KRT10, KRT16
34asthma10.0
35hepatocellular carcinoma10.0
36myelodysplastic syndrome10.0
37acrokeratosis verruciformis10.0
38neurofibromatosis, type 110.0
39adult t-cell leukemia10.0
40autosomal recessive disease10.0
41artemis deficiency10.0
42cutaneous t cell lymphoma10.0
43lepromatous leprosy10.0
44sarcoma10.0
45common wart10.0
46cryptococcosis10.0
47plantar wart10.0
48vaginitis10.0
49dermatitis10.0
50dyskeratosis congenita10.0

Graphical network of the top 20 diseases related to Epidermodysplasia Verruciformis:



Diseases related to epidermodysplasia verruciformis

Symptoms for Epidermodysplasia Verruciformis

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Symptoms by clinical synopsis from OMIM:

226400

Clinical features from OMIM:

226400

Symptoms:

 11 52 (show all 12)
  • l
  • seborrheic dermatitis
  • hypopigmented skin patches
  • recurrent skin infections
  • abnormality of the immune system
  • squamous cell carcinoma
  • multiple cafe-au-lait spots
  • teleangiectasia of the skin
  • papule
  • skin plaque
  • pustule
  • verrucae

HPO human phenotypes related to Epidermodysplasia Verruciformis:

(show all 10)
id Description Frequency HPO Source Accession
1 seborrheic dermatitis hallmark (90%) HP:0001051
2 pustule hallmark (90%) HP:0200039
3 skin ulcer hallmark (90%) HP:0200042
4 verrucae hallmark (90%) HP:0200043
5 cafe-au-lait spot typical (50%) HP:0000957
6 hypopigmented skin patches typical (50%) HP:0001053
7 telangiectasia of the skin occasional (7.5%) HP:0100585
8 abnormality of metabolism/homeostasis HP:0001939
9 basal cell carcinoma HP:0002671
10 verrucae HP:0200043

UMLS symptoms related to Epidermodysplasia Verruciformis:


penile warts

Drugs & Therapeutics for Epidermodysplasia Verruciformis

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Drugs for Epidermodysplasia Verruciformis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Ethanol197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2
Glycolic acid1379-14-1757
Synonyms:
2-Hydroxyacetate
2-Hydroxyacetic acid
GlyPure
GlyPure 70
Glycocide
Glycolate
Glycolic acid
Glycollate
Glycollic acid
 
Hydroxyacetate
Hydroxyacetic acid
Hydroxyethanoate
Hydroxyethanoic Acid
Hydroxyethanoic acid
Sodium glycolate
a-Hydroxyacetate
a-Hydroxyacetic acid
alpha-Hydroxyacetate
alpha-Hydroxyacetic acid

Interventional clinical trials:

idNameStatusNCT IDPhase
1Acquired Epidermodysplasia Verruciformis (EV) Syndrome in HIV-infected Pediatric PatientsCompletedNCT01289171
2Evaluation of the Effectiveness of an Alcohol Based Hand Gel for the Reduction of Warts on the HandsCompletedNCT00973856

Search NIH Clinical Center for Epidermodysplasia Verruciformis


Cochrane evidence based reviews: epidermodysplasia verruciformis

Genetic Tests for Epidermodysplasia Verruciformis

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Genetic tests related to Epidermodysplasia Verruciformis:

id Genetic test Affiliating Genes
1 Epidermodysplasia Verruciformis25 23 TMC6, TMC8

Anatomical Context for Epidermodysplasia Verruciformis

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MalaCards organs/tissues related to Epidermodysplasia Verruciformis:

34
Skin, T cells, Myeloid, Testes, Eye, Brain

FMA organs/tissues related to Epidermodysplasia Verruciformis:

17
Skin

Animal Models for Epidermodysplasia Verruciformis or affiliated genes

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Publications for Epidermodysplasia Verruciformis

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Articles related to Epidermodysplasia Verruciformis:

(show top 50)    (show all 388)
idTitleAuthorsYear
1
Remission of an epidermodysplasia verruciformis-like eruption in an HIV-positive man long after immune restoration. (26243233)
2015
2
Human immunodeficiency virus (HIV)-associated epidermodysplasia verruciformis eradicated after interferon-I+ and ribavirin treatment. (24527965)
2014
3
Conjunctival squamous cell carcinoma with intraocular invasion after radiotherapy in epidermodysplasia verruciformis. (24767238)
2014
4
Efficacy of oral zinc therapy in epidermodysplasia verruciformis with squamous cell carcinoma. (24616858)
2014
5
The transmembrane channel-like protein family and human papillomaviruses: Insights into epidermodysplasia verruciformis and progression to squamous cell carcinoma. (24800179)
2014
6
Epidermodysplasia Verruciformis-like Skin Eruption in an HIV-positive Patient. (25589883)
2014
7
Cutaneous Granulomas and Epidermodysplasia Verruciformis in Early Onset Combined Immunodeficiency Syndrome. (24247584)
2013
8
Epidermodysplasia Verruciformis in Lipoid Proteinosis: Case Report and Discussion of Pathophysiology. (23534907)
2013
9
Multiple Low-Grade Sarcomas of Fibroblastic Type in the Setting of HIV and Acquired Epidermodysplasia Verruciformis. (23759878)
2013
10
Characterization of beta papillomavirus E4 expression in tumours from Epidermodysplasia Verruciformis patients and in experimental models. (22217391)
2012
11
Acquired Epidermodysplasia Verruciformis in a Child with Atopic Dermatitis. (22938530)
2012
12
Merkel cell carcinoma presenting in a young patient as a forme fruste of variant epidermodysplasia verruciformis. (21839331)
2011
13
Epidermodysplasia verruciformis in human immunodeficiency virus-infected patients: a marker of human papillomavirus-related disorders not affected by antiretroviral therapy. (21242344)
2011
14
Seroreactivity of 38 human papillomavirus types in epidermodysplasia verruciformis patients, relatives, and controls. (19924140)
2010
15
Merkel cell polyomavirus in Merkel cell carcinoma from a Brazilian epidermodysplasia verruciformis patient. (20398819)
2010
16
Epidermodysplasia verruciformis-like syndrome in association with systemic lupus erythematosus. (19178492)
2009
17
High beta-HPV DNA loads and strong seroreactivity are present in epidermodysplasia verruciformis. (18923444)
2009
18
Epidermodysplasia verruciformis-associated and genital-mucosal high-risk human papillomavirus DNA are prevalent in nevus sebaceus of Jadassohn. (18638629)
2008
19
Dermoscopy in epidermodysplasia verruciformis. (16393609)
2006
20
A homozygous nonsense mutation in the EVER2 gene leads to epidermodysplasia verruciformis. (16045695)
2005
21
Epidermodysplasia verruciformis-like eruption associated with HIV infection. (15115519)
2004
22
Epidermodysplasia verruciformis. (12938792)
2003
23
Do epidermodysplasia verruciformis human papillomaviruses contribute to malignant and benign epidermal proliferations? (12020228)
2002
24
Groin eruption in an HIV-positive man: epidermodysplasia verruciformis (EDV). (11939816)
2002
25
HPV5b variant in a neoplastic lesion of an Italian patient affected by epidermodysplasia verruciformis. (11701412)
2001
26
Distinctive distribution of human papillomavirus type 16 and type 20 DNA in the tonsillar and the skin carcinomas of a patient with epidermodysplasia verruciformis. (11069510)
2000
27
A novel human papillomavirus DNA sequence related to epidermodysplasia verruciformis-associated types isolated from recurrent scar carcinoma. (10376716)
1999
28
Human papillomavirus DNA in non-melanoma skin cancers of a renal transplant recipient: detection of a new sequence related to epidermodysplasia verruciformis associated types. (8980287)
1997
29
Skin autografts in epidermodysplasia verruciformis: human papillomavirus-associated cutaneous changes need over 20 years for malignant conversion. (9331078)
1997
30
P53 expression and human papillomavirus infection in transplant recipients and in patients with epidermodysplasia verruciformis. (8746364)
1996
31
Spiny hyperkeratosis of the fingers as an unusual sign of epidermodysplasia verruciformis. (7868732)
1995
32
p53 protein expression in viral warts from patients with epidermodysplasia verruciformis. (7748739)
1995
33
Involvement of human papillomavirus type 20 in epidermodysplasia verruciformis skin carcinogenesis. (8027315)
1994
34
Unique topography of DNA-protein interactions in the non-coding region of epidermodysplasia verruciformis-associated human papillomaviruses. (1662691)
1991
35
Epidermodysplasia verruciformis-associated papillomavirus infection complicating human immunodeficiency virus disease. (1847068)
1991
36
The heterogeneity of tumours associated with epidermodysplasia verruciformis. (2436421)
1987
37
Epidermodysplasia verruciformis-associated human papillomavirus 8: genomic sequence and comparative analysis. (3009874)
1986
38
Identification of HLA antigens in familial and non-familial epidermodysplasia verruciformis. (3856540)
1985
39
Characterization of two HPV-3 related papillomaviruses from common warts that are distinct clinically from flat warts or epidermodysplasia verruciformis. (6302170)
1983
40
Regression of the lesions of epidermodysplasia verruciformis. (7104203)
1982
41
Human papillomavirus DNA in cutaneous primary and metastasized squamous cell carcinomas from patients with epidermodysplasia verruciformis. (6280194)
1982
42
Epidermodysplasia verruciformis (Lewandowsky-Lutz): the revived report of a case seen in 1944. (7451006)
1980
43
UV-induced DNA repair synthesis in patients with epidermodysplasia verruciformis. (6244993)
1980
44
Epidermodysplasia verruciformis: viral particles in early malignant lesions. (701842)
1978
45
The virus of epidermodysplasia verruciformis: electron microscopic and fluorescent antibody studies. (808576)
1975
46
Epidermodysplasia verruciformis. 3. Ultraviolet micro-irradiation of cells in culture. (4840892)
1974
47
Epidermodysplasia verruciformis as a model in studies on the role of papovaviruses in oncogenesis. (5061309)
1972
48
The ultrastructure of transitional states to Bowen's disease and invasive Bowen's carcinoma in epidermodysplasia verruciformis. (5414361)
1970
49
Epidermodysplasia verruciformis and epidermoid carcinoma. Electron microscopic observations. (4291940)
1967
50
Case for diagnosis: epidermodysplasia verruciformis. (14848416)
1951

Variations for Epidermodysplasia Verruciformis

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Clinvar genetic disease variations for Epidermodysplasia Verruciformis:

5
id Gene Variation Type Significance SNP ID Assembly Location
1TMC8TMC8, 1-BP DEL, 754TdeletionPathogenic
2TMC8NM_152468.4(TMC8): c.1084G> T (p.Glu362Ter)single nucleotide variantPathogenicrs121908330GRCh37Chr 17, 76131047: 76131047
3TMC6NM_007267.7(TMC6): c.280C> T (p.Arg94Ter)single nucleotide variantPathogenicrs121908327GRCh37Chr 17, 76121957: 76121957
4TMC6NM_007267.7(TMC6): c.1726G> T (p.Glu576Ter)single nucleotide variantPathogenicrs121908328GRCh37Chr 17, 76115463: 76115463
5TMC6NM_007267.7(TMC6): c.744C> A (p.Tyr248Ter)single nucleotide variantPathogenicrs121908329GRCh37Chr 17, 76120752: 76120752
6TMC6NM_007267.7(TMC6): c.892-2A> Tsingle nucleotide variantPathogenicrs769471844GRCh37Chr 17, 76120262: 76120262

Expression for genes affiliated with Epidermodysplasia Verruciformis

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Search GEO for disease gene expression data for Epidermodysplasia Verruciformis.

Pathways for genes affiliated with Epidermodysplasia Verruciformis

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Pathways related to Epidermodysplasia Verruciformis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
18.5CD1A, CDH1, IL10

GO Terms for genes affiliated with Epidermodysplasia Verruciformis

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Cellular components related to Epidermodysplasia Verruciformis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cortical actin cytoskeletonGO:003086410.1CDH1, CORO1A
2intermediate filamentGO:00058829.6KRT10, KRT16, KRT4
3extracellular exosomeGO:00700628.0CDH1, CORO1A, ECM1, KRT10, KRT16, TMC6

Biological processes related to Epidermodysplasia Verruciformis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1leukocyte chemotaxisGO:00305959.6CORO1A, IL10
2ion transportGO:00068119.4TMC3, TMC6, TMC8

Sources for Epidermodysplasia Verruciformis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet