EBA
MCID: EPD006
MIFTS: 63

Epidermolysis Bullosa Acquisita (EBA) malady

Rare diseases, Skin diseases categories
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Summaries for Epidermolysis Bullosa Acquisita

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NIH Rare Diseases:42 Epidermolysis bullosa acquisita (eba) is a rare autoimmune disorder that causes the skin to blister in response to minor injury. common areas of blistering include the hands, feet, knees, elbows, and buttocks. it can also affect the mouth, nose, and eyes. some affected people have other health problems such as crohn's disease, systemic lupus erythematosus, amyloidosis, or multiple myeloma. eba is not inherited and usually occurs in adulthood. treatment aims to protect the skin, stop the formation of blisters, and promote healing. immunosuppressive drugs may be used to reduce the body's autoimmune response. last updated: 2/27/2014

MalaCards based summary: Epidermolysis Bullosa Acquisita, also known as acquired epidermolysis bullosa, is related to epidermolysis bullosa and bullous pemphigoid, and has symptoms including vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment, enanthema/aphtosa/aphta/leukoplakia and hair and scalp anomalies. An important gene associated with Epidermolysis Bullosa Acquisita is LAD1 (ladinin 1), and among its related pathways are a6b1 and a6b4 Integrin signaling and Inflammatory Response Pathway. The compounds mizoribine and lentinan have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and colon, and related mouse phenotypes are respiratory system and renal/urinary system.

Wikipedia:65 Epidermolysis bullosa acquisita is a chronic subepidermal blistering disease associated with... more...

Aliases & Classifications for Epidermolysis Bullosa Acquisita

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH, 26ICD10 via Orphanet, 25ICD10
See all sources

Epidermolysis Bullosa Acquisita, Aliases & Descriptions:

Name: Epidermolysis Bullosa Acquisita 8 42 10 44 48 62
Acquired Epidermolysis Bullosa 8 42 48
 
Eb Acquisita 42
Eba 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases
Orphanet: 48 
Rare skin diseases


Characteristics (Orphanet epidemiological data):

48
epidermolysis bullosa acquisita:
Inheritance: Sporadic; Age of onset: Adulthood


External Ids:

Disease Ontology8 DOID:4313
NCIt39 C84690
MeSH34 D016107
SNOMED-CT57 200911009, 2772003
ICD10 via Orphanet26 L12.3
ICD1025 L12.3

Related Diseases for Epidermolysis Bullosa Acquisita

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Diseases related to Epidermolysis Bullosa Acquisita via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1epidermolysis bullosa32.4COL17A1, ITGB4, DST, LAMC2, LAMA3, COL7A1
2bullous pemphigoid32.1COL7A1, COL17A1, DST
3relapsing polychondritis31.5MATN1
4dermatitis herpetiformis31.0CD79A, IL2RB
5dermatitis30.8CD79A, CSF2, DSG1
6mucous membrane pemphigoid30.7COL17A1, CD79A, ITGB4, DST, LAMA3, LAMC2
7systemic lupus erythematosus30.7SERPINH1, IL2RB, CD79A, IL2RA, HLA-DRB1
8ulcerative colitis30.5LAMC2, CD79A, IL2RA, HLA-DRB1
9eosinophilia30.4IL2RA, CSF2, IL2RB, CD79A
10hepatitis30.3HLA-DRB1, IL2RB, TGFB1
11pneumonia30.3IL2RB, CSF2, TGFB1, CD79A
12graft versus host disease30.0IL2RB, CSF2, HLA-DRB1, IL2RA
13cicatricial pemphigoid10.9
14lupus erythematosus10.9
15crohn's disease10.8
16esophagitis10.7
17amyloidosis10.6
18multiple myeloma10.6
19laryngitis10.6
20myeloma10.6
21psoriasis10.6
22inflammatory bowel disease10.6
23bullous systemic lupus erythematosus10.6
24ocular cicatricial pemphigoid10.6ITGB4
25giardiasis10.5CD79A
26colitis10.5
27blindness10.5
28junctional epidermolysis bullosa, non-herlitz type10.4COL17A1, ITGB4
29herpes gestationis10.4DST, COL17A1
30kindler syndrome10.4COL7A1, ITGB4
31junctional epidermolysis bullosa, herlitz type10.4LAMC2, LAMA3
32immunoglobulin g deficiency10.4FCGRT, CD79A
33epidermolysis bullosa dystrophica10.3
34pancreatic cancer10.3
35vitiligo10.3
36wilson disease10.3
37pulmonary tuberculosis10.3
38cryoglobulinemia10.3
39hepatitis c10.3
40cutaneous lupus erythematosus10.3
41factor viii deficiency10.3
42graves' disease10.3
43porphyria cutanea tarda10.3
44conjunctivitis10.3
45cystitis10.3
46nephrotic syndrome10.3
47pancreatitis10.3
48periodontitis10.3
49porphyria10.3
50tuberculosis10.3

Graphical network of the top 20 diseases related to Epidermolysis Bullosa Acquisita:



Diseases related to epidermolysis bullosa acquisita

Symptoms for Epidermolysis Bullosa Acquisita

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Symptoms:

48 (show all 11)
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • enanthema/aphtosa/aphta/leukoplakia
  • hair and scalp anomalies
  • follicular/erythematous/edematous papules/milium
  • nails anomalies
  • abnormal scarring/cheloids/hypertrophic scars
  • urticaria
  • pruritus/itching
  • thick skin/pachydermia/orange skin
  • intestinal/colonic anomaly
  • acute abdominal pain/colic

HPO human phenotypes related to Epidermolysis Bullosa Acquisita:

(show all 9)
id Description Frequency HPO Source Accession
1 abnormality of the oral cavity hallmark (90%) HP:0000163
2 abnormal blistering of the skin hallmark (90%) HP:0008066
3 abnormality of the nail typical (50%) HP:0001597
4 atypical scarring of skin occasional (7.5%) HP:0000987
5 pruritus occasional (7.5%) HP:0000989
6 urticaria occasional (7.5%) HP:0001025
7 thickened skin occasional (7.5%) HP:0001072
8 abdominal pain occasional (7.5%) HP:0002027
9 abnormality of the intestine occasional (7.5%) HP:0002242

Drugs & Therapeutics for Epidermolysis Bullosa Acquisita

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Drug clinical trials:

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Genetic Tests for Epidermolysis Bullosa Acquisita

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Anatomical Context for Epidermolysis Bullosa Acquisita

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MalaCards organs/tissues related to Epidermolysis Bullosa Acquisita:

32
Skin, Eye, Colon, Lymph node, Testes, T cells, B cells, Bone marrow, Bone, Lung, Neutrophil

Animal Models for Epidermolysis Bullosa Acquisita or affiliated genes

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MGI Mouse Phenotypes related to Epidermolysis Bullosa Acquisita:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.3TGFB1, ITGB4, SERPINH1, LAMC2, CSF2
2MP:00053678.0CSF2, ITGB4, DST, TGFB1, CD79A, LAMC2
3MP:00053827.9TGFB1, LAMC2, CSF2, COL7A1, ITGB4, SERPINH1
4MP:00053817.8IL2RA, ITGB4, DST, SERPINH1, TGFB1, LAMC2
5MP:00107717.4LAMA3, IL2RB, CSF2, COL17A1, COL7A1, ITGB4
6MP:00053977.2CSF2, IL2RB, IL2RA, DST, TGFB1, CD79A
7MP:00053877.1FCGRT, CSF2, ITGB4, LAMC2, CD79A, COL17A1
8MP:00053786.9TGFB1, IL2RA, DST, LAMA3, IL2RB, COL7A1
9MP:00107686.6TGFB1, IL2RB, LAMA3, LAMC2, CSF2, COL17A1

Publications for Epidermolysis Bullosa Acquisita

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Articles related to Epidermolysis Bullosa Acquisita:

(show top 50)    (show all 352)
idTitleAuthorsYear
1
Recombinant Soluble CD32 Suppresses Disease Progression in Experimental Epidermolysis Bullosa Acquisita. (25330298)
2014
2
Metabolite analysis distinguishes between mice with epidermolysis bullosa acquisita and healthy mice. (23800341)
2013
3
Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita. (23956869)
2013
4
Epidermolysis bullosa acquisita and inflammatory bowel disease: a review of the literature. (23517353)
2013
5
Images in clinical medicine. Epidermolysis bullosa acquisita. (23534583)
2013
6
B cells, dendritic cells, and macrophages are required to induce an autoreactive CD4 helper T cell response in experimental epidermolysis bullosa acquisita. (23960233)
2013
7
Retrospective study of the clinical, histologic, and immunologic features of epidermolysis bullosa acquisita in 9 patients. (23895729)
2013
8
Peristomal Epidermolysis Bullosa Acquisita in a Patient with Crohn's Disease. (24322876)
2013
9
Epidermolysis bullosa acquisita. (23368767)
2013
10
Sensitivity of different assays for the serological diagnosis of epidermolysis bullosa acquisita: analysis of a cohort of 24 Italian patients. (24321031)
2013
11
A case of epidermolysis bullosa acquisita associated with laryngeal stenosis. (22215014)
2012
12
Detection of collagen VII autoantibodies to NC1 and NC2 domains of collagen VII by ELISA in suspected epidermolysis bullosa acquisita and bullous lupus erythematosus patients. (22225828)
2012
13
Accuracy of indirect immunofluorescence on sodium chloride-split skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. (22016274)
2011
14
Current concepts in the treatment of epidermolysis bullosa acquisita. (21254861)
2011
15
Could cytomegalovirus infection play a causative role in epidermolysis bullosa acquisita? (21659069)
2011
16
Epidermolysis bullosa acquisita with moderately severe Dysphagia due to esophageal strictures. (21716557)
2011
17
Metal sensitization precipitates skin blistering in epidermolysis bullosa acquisita. (20507396)
2010
18
Epidermolysis bullosa acquisita: what's new? (20507385)
2010
19
Severe acral contractures and nail loss in a patient with mechano-bullous Epidermolysis bullosa acquisita. (20522419)
2010
20
Inflammatory epidermolysis bullosa acquisita mimicking toxic epidermal necrolysis and dermatitis herpetiformis. (19663858)
2009
21
Crohn's disease, relapsing polychondritis and epidermolysis bullosa acquisita: an immune-mediated inflammatory syndrome. (18238795)
2008
22
A quick and simple serum test to differentiate bullous pemphigoid, epidermolysis bullosa acquisita, and anti-epiligrin cicatricial pemphigoid. (18718187)
2008
23
Clinical response of severe mechanobullous epidermolysis bullosa acquisita to combined treatment with immunoadsorption and rituximab (anti-CD20 monoclonal antibodies). (17309999)
2007
24
A case of epidermolysis bullosa acquisita with autoantibody to anti-p200 pemphigoid antigen and exfoliative esophagitis. (16707891)
2006
25
Epidermolysis bullosa acquisita: diagnosis by fluorescence overlay antigen mapping and clinical response to high-dose intravenous immunoglobulin. (16309488)
2006
26
Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid. (15538734)
2004
27
Childhood epidermolysis bullosa acquisita with autoantibodies against all 3 structural domains of type VII collagen. (14988700)
2004
28
A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading. (15243536)
2004
29
Anti-epiligrin cicatricial pemphigoid and epidermolysis bullosa acquisita: differentiation by use of indirect immunofluorescence microscopy. (12664017)
2003
30
Epidermolysis bullosa acquisita in childhood. (12692360)
2003
31
Novel localised variant of canine epidermolysis bullosa acquisita. (10718593)
2000
32
Treatment of epidermolysis bullosa acquisita with mycophenolate mofetil and autologous keratinocyte grafting. (10583185)
1999
33
Epidermolysis bullosa acquisita exacerbated by systemic estrogen and progesterone treatment and pregnancy. (9146549)
1997
34
Linear IgA disease with clinical and immunopathological features of epidermolysis bullosa acquisita. (9263315)
1997
35
Bullous pemphigoid and epidermolysis bullosa acquisita. Differentiation by fluorescence overlay antigen mapping. (8629822)
1996
36
Epidermolysis bullosa acquisita: report of a case with comparison of immunogold electron microscopy using pre- and postembedding labelling. (8745903)
1996
37
Successful treatment of epidermolysis bullosa acquisita using intravenous immunoglobulins. (7772494)
1995
38
Laryngeal manifestations of epidermolysis bullosa acquisita. (7646856)
1995
39
Epidermolysis bullosa acquisita with oesophageal stenosis. (1390148)
1992
40
Epidermolysis bullosa acquisita and associated symptomatic esophageal webs. (1998368)
1991
41
Direct immunofluorescence studies of sodium chloride-separated skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. (2180996)
1990
42
The presence of intra-lamina lucida blister formation in epidermolysis bullosa acquisita: possible role of leukocytes. (2642510)
1989
43
Epidermolysis bullosa acquisita in childhood. Differentiation from hereditary epidermolysis bullosa. (2662910)
1989
44
Epidermal basement membrane alterations in epidermolysis bullosa acquisita. (3074092)
1988
45
Epidermolysis bullosa acquisita antigen: relationship between the collagenase-sensitive and -insensitive domains. (2828479)
1988
46
Severe ocular involvement in a patient with epidermolysis bullosa acquisita. (3819091)
1987
47
Acidic glycosaminoglycans in cultured skin fibroblasts of a patient with epidermolysis bullosa acquisita. (7404577)
1980
48
Epidermolysis bullosa acquisita: a clinical disorder of varied etiologies. Two cases and a review of immunologic and other reported findings. (7005274)
1980
49
Vitamin E treatment of epidermolysis bullosa acquisita. (1022216)
1976
50
Epidermolysis bullosa acquisita. Report of three cases and review of all published cases. (4321800)
1971

Variations for Epidermolysis Bullosa Acquisita

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Expression for genes affiliated with Epidermolysis Bullosa Acquisita

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Expression patterns in normal tissues for genes affiliated with Epidermolysis Bullosa Acquisita

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Pathways for genes affiliated with Epidermolysis Bullosa Acquisita

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Pathways related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0COL17A1, ITGB4
29.5IL2RB, IL2RA, LAMC2
39.4IL2RA, IL2RB, CD79A
4
Show member pathways
9.2LAMC2, COL17A1, LAMA3, DST, ITGB4
5
Show member pathways
9.2LAMC2, LAMA3, ITGB4, DST, COL17A1
6
Show member pathways
Type III interferon signaling37
9.2CSF2, IL2RA, IL2RB
7
Show member pathways
9.2IL2RB, CSF2, IL2RA
8
Show member pathways
9.1HLA-DRB1, IL2RA, IL2RB
9
Show member pathways
Immune response IL 22 signaling pathway60
G protein signaling N RAS regulation pathway60
9.1HLA-DRB1, IL2RA, IL2RB
10
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.1HLA-DRB1, IL2RB, IL2RA
118.9LAMA3, IL2RA, LAMC2, IL2RB, ITGB4
128.9CSF2, IL2RA, HLA-DRB1
13
Show member pathways
Proteogylcan syndecan-mediated signaling events37
8.9ITGB4, TGFB1, LAMC2, LAMA3
14
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
8.9CD79A, CSF2, TGFB1
158.9IL2RB, IL2RA, TGFB1
168.8TGFB1, CSF2, LAMA3
178.8TGFB1, MATN1, LAMA3
18
Show member pathways
8.8HLA-DRB1, IL2RA, IL2RB, CD79A
19
Show member pathways
8.7IL2RA, IL2RB, ITGB4, TGFB1
208.6IL2RA, TGFB1, HLA-DRB1
218.6TGFB1, LAMC2, LAMA3, CSF2
22
Show member pathways
8.6ITGB4, SERPINH1, LAMC2, LAMA3, DST, COL17A1
23
Show member pathways
8.5IL2RB, CSF2, IL2RA, HLA-DRB1
248.5CSF2, TGFB1, HLA-DRB1
258.5CSF2, TGFB1, HLA-DRB1
26
Show member pathways
8.5TGFB1, LAMA3, HLA-DRB1, LAMC2
27
Show member pathways
8.4COL7A1, ITGB4, TGFB1, LAMC2, LAMA3, COL17A1
28
Show member pathways
8.3IL2RA, TGFB1, IL2RB, CSF2
29
Show member pathways
8.1HLA-DRB1, CD79A, TGFB1, ITGB4, IL2RA
30
Show member pathways
8.1IL2RB, IL2RA, CSF2, ITGB4, TGFB1
317.7HLA-DRB1, TGFB1, IL2RB, CSF2, IL2RA
32
Show member pathways
7.7IL2RA, COL7A1, LAMA3, COL17A1, LAMC2, CD79A
33
Show member pathways
7.2LAMA3, MATN1, COL17A1, COL7A1, ITGB4, DST
34
Show member pathways
7.1ITGB4, COL17A1, IL2RB, CSF2, COL7A1, IL2RA

Compounds for genes affiliated with Epidermolysis Bullosa Acquisita

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Compounds related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show top 50)    (show all 79)
idCompoundScoreTop Affiliating Genes
1mizoribine4410.1IL2RA, CD79A
2lentinan4410.1IL2RB, IL2RA
3mycophenolate4410.1IL2RB, IL2RA
4thymoglobulin4410.0IL2RA, IL2RB
5gluten4410.0IL2RA, CD79A
6denileukin diftitox44 50 1112.0IL2RA, IL2RB
7kalinin449.9LAMC2, ITGB4, DST, LAMA3
8con a449.8IL2RA, IL2RB, CD79A
9mycophenolate mofetil44 50 1111.8CD79A, IL2RB, IL2RA
10gold449.8DST, IL2RB, COL17A1, LAMC2
11delta9-tetrahydrocannabinol449.6IL2RA, IL2RB
12azathioprine44 2 50 1112.6IL2RA, CD79A, IL2RB
13pentoxifylline44 1110.5CSF2, IL2RB, IL2RA
14ifn-alpha449.5IL2RA, IL2RB, CSF2
15okt3449.4IL2RA, CD79A, IL2RB, CSF2
16neopterin449.3IL2RA, CD79A, CSF2, IL2RB
17betacarotene449.3IL2RA, CD79A, TGFB1
18pmma449.3CD79A, CSF2, TGFB1
19theophylline44 28 24 1112.3IL2RA, CD79A, TGFB1
20alginate449.3TGFB1, MATN1, CD79A
21erythromycin44 2 50 1112.2IL2RB, IL2RA, TGFB1
22prednisolone44 28 1111.1IL2RA, IL2RB, CD79A
23norepinephrine44 24 1111.1CD79A, IL2RB, IL2RA, CSF2
24procollagen449.0TGFB1, SERPINH1, MATN1
25tacrolimus44 50 1111.0IL2RB, TGFB1, IL2RA, CD79A
26bleomycin44 1110.0CSF2, IL2RA, TGFB1
27methacholine44 50 1110.9CD79A, CSF2, IL2RB, TGFB1
28verapamil44 28 50 24 1112.9IL2RB, TGFB1, IL2RA
291,25 dihydroxy vitamin d3448.8IL2RB, TGFB1, CSF2
3012-o-tetradecanoylphorbol 13-acetate448.8IL2RB, CSF2, TGFB1, DST
31il 10448.8CSF2, TGFB1, IL2RA, IL2RB
32nifedipine44 28 50 1111.8CSF2, IL2RB, IL2RA, TGFB1
33vitamin d448.7CD79A, IL2RA, CSF2, TGFB1
34paraffin448.7IL2RA, DST, TGFB1, CD79A
35rantes448.7IL2RA, TGFB1, CSF2, IL2RB
36arginine448.7CD79A, HLA-DRB1, IL2RB, IL2RA, COL7A1
37cycloheximide448.6TGFB1, DST, CSF2, COL17A1, IL2RB
38ivig448.6IL2RB, IL2RA, DSG1, FCGRT, CSF2, CD79A
39aspirin44 50 28 2411.5IL2RA, IL2RB, CSF2, CD79A, TGFB1
40polysaccharide448.5CSF2, IL2RB, IL2RA, TGFB1, CD79A
41histamine44 28 2410.5TGFB1, IL2RA, IL2RB, CD79A, CSF2
42pge2448.5CD79A, IL2RB, IL2RA, TGFB1, CSF2
43rituximab44 50 1110.5TGFB1, CD79A, CSF2, IL2RA, DSG1
44methotrexate50 44 1110.4CD79A, TGFB1, IL2RA, IL2RB, HLA-DRB1
45dexamethasone44 50 28 1111.3IL2RB, CD79A, TGFB1, IL2RA, CSF2
46cyclosporin a44 28 6110.2CD79A, TGFB1, CSF2, IL2RB, SERPINH1, IL2RA
47vegf448.2IL2RA, CD79A, TGFB1, SERPINH1, IL2RB, CSF2
48serine448.1SERPINH1, TGFB1, ITGB4, IL2RB, COL7A1, COL17A1
49tyrosine448.1IL2RA, ITGB4, SERPINH1, HLA-DRB1, COL17A1, CSF2
50retinoic acid44 248.7MATN1, CSF2, CD79A, TGFB1, DSG1, ITGB4

GO Terms for genes affiliated with Epidermolysis Bullosa Acquisita

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Cellular components related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1laminin-5 complexGO:00561010.1LAMA3, LAMC2
2basal plasma membraneGO:00992510.0ITGB4, DST
3hemidesmosomeGO:03005610.0COL17A1, ITGB4, DST
4cell leading edgeGO:0312529.7ITGB4, DST
5endoplasmic reticulum lumenGO:0057889.5COL7A1, SERPINH1, COL17A1
6basement membraneGO:0056049.2DST, LAMA3, LAD1, ITGB4, COL17A1, COL7A1
7external side of plasma membraneGO:0098979.0CD79A, IL2RA, IL2RB, HLA-DRB1
8extracellular spaceGO:0056158.2COL7A1, LAMC2, CSF2, TGFB1, SERPINH1
9extracellular regionGO:0055767.7LAMA3, COL17A1, COL7A1, MATN1, TGFB1, LAMC2
10plasma membraneGO:0058866.8IL2RA, TGFB1, DSG1, ITGB4, HLA-DRB1, IL2RB

Biological processes related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1cell motilityGO:0488709.9DST, ITGB4
2cell junction assemblyGO:0343299.8COL17A1, ITGB4, LAMC2, LAMA3
3epidermis developmentGO:0085449.7LAMA3, LAMC2, COL7A1, COL17A1
4extracellular matrix disassemblyGO:0226179.6LAMA3, LAMC2, COL7A1, COL17A1
5hemidesmosome assemblyGO:0315819.5LAMA3, LAMC2, DST, ITGB4, COL17A1
6inflammatory response to antigenic stimulusGO:0024379.4IL2RA, HLA-DRB1
7cell adhesionGO:0071559.3LAMA3, LAMC2, DST, ITGB4, COL7A1
8response to woundingGO:0096119.3ITGB4, DST, TGFB1
9negative regulation of immune responseGO:0507779.3IL2RA, TGFB1
10response to progesteroneGO:0325709.2DSG1, TGFB1
11myeloid dendritic cell differentiationGO:0430118.8CSF2, TGFB1
12negative regulation of T cell proliferationGO:0421308.8IL2RA, TGFB1, HLA-DRB1
13immune responseGO:0069558.7HLA-DRB1, FCGRT, IL2RA, CSF2
14extracellular matrix organizationGO:0301987.5MATN1, LAMA3, LAMC2, TGFB1, SERPINH1, DST

Molecular functions related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1interleukin-2 bindingGO:0199769.7IL2RB, IL2RA
2interleukin-2 receptor activityGO:0049119.4IL2RB, IL2RA

Products for genes affiliated with Epidermolysis Bullosa Acquisita

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Sources for Epidermolysis Bullosa Acquisita

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet