EBA
MCID: EPD006
MIFTS: 63

Epidermolysis Bullosa Acquisita (EBA) malady

Rare diseases, Skin diseases categories
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Summaries for Epidermolysis Bullosa Acquisita

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43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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Fully expand this MalaCard
NIH Rare Diseases:43 Epidermolysis bullosa acquisita (eba) is a rare autoimmune disorder that causes the skin to blister in response to minor injury. common areas of blistering include the hands, feet, knees, elbows, and buttocks. it can also affect the mouth, nose, and eyes. some affected people have other health problems such as crohn's disease, systemic lupus erythematosus, amyloidosis, or multiple myeloma. eba is not inherited and usually occurs in adulthood. treatment aims to protect the skin, stop the formation of blisters, and promote healing. immunosuppressive drugs may be used to reduce the body's autoimmune response. last updated: 2/27/2014

MalaCards: Epidermolysis Bullosa Acquisita, also known as acquired epidermolysis bullosa, is related to epidermolysis bullosa and bullous pemphigoid, and has symptoms including acute abdominal pain/colic, intestinal/colonic anomaly and enanthema/aphtosa/aphta/leukoplakia. An important gene associated with Epidermolysis Bullosa Acquisita is LAD1 (ladinin 1), and among its related pathways are a6b1 and a6b4 Integrin signaling and Inflammatory Response Pathway. The compounds mizoribine and lentinan have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and colon, and related mouse phenotypes are respiratory system and renal/urinary system.

Wikipedia:65 Epidermolysis bullosa acquisita is a chronic subepidermal blistering disease associated with... more...

Aliases & Classifications for Epidermolysis Bullosa Acquisita

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8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 49Orphanet, 62UMLS, 58SNOMED-CT, 40NCIt, 35MeSH, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases
Orphanet: 49 
Rare skin diseases


Characteristics (Orphanet epidemiological data):

49
epidermolysis bullosa acquisita:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

epidermolysis bullosa acquisita 8 43 10 45 49 62
acquired epidermolysis bullosa 8 43 49
eb acquisita 43
eba 43


External Ids:

Disease Ontology8 DOID:4313
NCIt40 C84690
MeSH35 D016107
SNOMED-CT58 2772003, 200911009
ICD10 via Orphanet26 L12.3
SNOMED-CT via Orphanet59 2772003
ICD1025 L12.3

Related Diseases for Epidermolysis Bullosa Acquisita

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17GeneCards, 18GeneDecks
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Diseases related to Epidermolysis Bullosa Acquisita via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1epidermolysis bullosa32.4COL17A1, LAMA3, LAMC2, DST, ITGB4, COL7A1
2bullous pemphigoid31.7COL17A1, COL7A1, DST
3cicatricial pemphigoid31.4COL17A1, COL7A1
4systemic lupus erythematosus31.0CD79A, IL2RB, IL2RA, SERPINH1, HLA-DRB1
5relapsing polychondritis30.9MATN1
6dermatitis30.7CD79A, CSF2, DSG1
7ulcerative colitis30.7CD79A, IL2RA, LAMC2, HLA-DRB1
8dermatitis herpetiformis30.6CD79A, IL2RB
9eosinophilia30.5IL2RA, IL2RB, CSF2, CD79A
10hepatitis30.5HLA-DRB1, TGFB1, IL2RB
11pneumonia30.4TGFB1, IL2RB, CSF2, CD79A
12graft versus host disease30.4HLA-DRB1, IL2RA, IL2RB, CSF2
13lupus erythematosus10.8
14crohn's disease10.8
15amyloidosis10.6
16esophagitis10.6
17inflammatory bowel disease10.6
18multiple myeloma10.6
19myeloma10.6
20psoriasis10.6
21mucous membrane pemphigoid10.6
22bullous systemic lupus erythematosus10.6
23laryngitis10.5
24blindness10.5
25hepatitis c10.3
26pulmonary tuberculosis10.3
27cryoglobulinemia10.3
28porphyria cutanea tarda10.3
29cutaneous lupus erythematosus10.3
30factor viii deficiency10.3
31vitiligo10.3
32graves' disease10.3
33epidermolysis bullosa dystrophica10.3
34conjunctivitis10.3
35cystitis10.3
36nephrotic syndrome10.3
37pancreatic cancer10.3
38pancreatitis10.3
39periodontitis10.3
40porphyria10.3
41tuberculosis10.3
42linear iga disease10.3
43toxic epidermal necrolysis10.3
44cytomegalovirus infection10.3
45dysphagia10.3
46subacute cutaneous lupus erythematosus10.3
47benign schwannoma10.3
48ocular cicatricial pemphigoid10.1ITGB4
49giardiasis10.1CD79A
50junctional epidermolysis bullosa, non-herlitz type10.1ITGB4, COL17A1

Graphical network of the top 20 diseases related to Epidermolysis Bullosa Acquisita:



Diseases related to epidermolysis bullosa acquisita

Symptoms for Epidermolysis Bullosa Acquisita

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49Orphanet
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Symptoms:

49 (show all 11)
  • acute abdominal pain/colic
  • intestinal/colonic anomaly
  • enanthema/aphtosa/aphta/leukoplakia
  • hair and scalp anomalies
  • follicular/erythematous/edematous papules/milium
  • nails anomalies
  • abnormal scarring/cheloids/hypertrophic scars
  • urticaria
  • pruritus/itching
  • thick skin/pachydermia/orange skin
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment

Drugs & Therapeutics for Epidermolysis Bullosa Acquisita

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Epidermolysis Bullosa Acquisita

Search NIH Clinical Center for Epidermolysis Bullosa Acquisita

Genetic Tests for Epidermolysis Bullosa Acquisita

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Anatomical Context for Epidermolysis Bullosa Acquisita

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33MalaCards
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MalaCards organs/tissues related to Epidermolysis Bullosa Acquisita:

33
Skin, Eye, Colon, Lymph node, B cells, Testes, T cells, Lung, Bone, Bone marrow

Animal Models for Epidermolysis Bullosa Acquisita or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Epidermolysis Bullosa Acquisita:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.3CSF2, ITGB4, SERPINH1, TGFB1, LAMC2
2MP:00053678.0LAMC2, TGFB1, DST, ITGB4, CSF2, CD79A
3MP:00053827.9LAMA3, LAMC2, TGFB1, SERPINH1, ITGB4, COL7A1
4MP:00053817.8LAMA3, LAMC2, TGFB1, SERPINH1, DST, ITGB4
5MP:00107717.4CSF2, LAMA3, LAMC2, TGFB1, DST, ITGB4
6MP:00053977.2FCGRT, TGFB1, DST, IL2RA, IL2RB, CSF2
7MP:00053877.1FCGRT, LAMC2, TGFB1, ITGB4, IL2RA, IL2RB
8MP:00053786.9LAMA3, TGFB1, SERPINH1, DST, IL2RA, IL2RB
9MP:00107686.6LAMA3, LAMC2, TGFB1, SERPINH1, DST, ITGB4

Publications for Epidermolysis Bullosa Acquisita

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52PubMed
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Articles related to Epidermolysis Bullosa Acquisita:

(show top 50)    (show all 345)
idTitleAuthorsYear
1
Metabolite analysis distinguishes between mice with epidermolysis bullosa acquisita and healthy mice. (23800341)
2013
2
Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita. (23956869)
2013
3
Epidermolysis bullosa acquisita and inflammatory bowel disease: a review of the literature. (23517353)
2013
4
Images in clinical medicine. Epidermolysis bullosa acquisita. (23534583)
2013
5
B cells, dendritic cells, and macrophages are required to induce an autoreactive CD4 helper T cell response in experimental epidermolysis bullosa acquisita. (23960233)
2013
6
Retrospective study of the clinical, histologic, and immunologic features of epidermolysis bullosa acquisita in 9 patients. (23895729)
2013
7
Peristomal Epidermolysis Bullosa Acquisita in a Patient with Crohn's Disease. (24322876)
2013
8
Epidermolysis bullosa acquisita. (23368767)
2013
9
Sensitivity of different assays for the serological diagnosis of epidermolysis bullosa acquisita: analysis of a cohort of 24 Italian patients. (24321031)
2013
10
Detection of collagen VII autoantibodies to NC1 and NC2 domains of collagen VII by ELISA in suspected epidermolysis bullosa acquisita and bullous lupus erythematosus patients. (22225828)
2012
11
Accuracy of indirect immunofluorescence on sodium chloride-split skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. (22016274)
2011
12
Current concepts in the treatment of epidermolysis bullosa acquisita. (21254861)
2011
13
Could cytomegalovirus infection play a causative role in epidermolysis bullosa acquisita? (21659069)
2011
14
Epidermolysis bullosa acquisita with moderately severe Dysphagia due to esophageal strictures. (21716557)
2011
15
Metal sensitization precipitates skin blistering in epidermolysis bullosa acquisita. (20507396)
2010
16
Epidermolysis bullosa acquisita: what's new? (20507385)
2010
17
Severe acral contractures and nail loss in a patient with mechano-bullous Epidermolysis bullosa acquisita. (20522419)
2010
18
Inflammatory epidermolysis bullosa acquisita mimicking toxic epidermal necrolysis and dermatitis herpetiformis. (19663858)
2009
19
Periorbital papulovesicular eruption in an elderly man. Localized periorbital epidermolysis bullosa acquisita (EBA). (19451507)
2009
20
Crohn's disease, relapsing polychondritis and epidermolysis bullosa acquisita: an immune-mediated inflammatory syndrome. (18238795)
2008
21
A quick and simple serum test to differentiate bullous pemphigoid, epidermolysis bullosa acquisita, and anti-epiligrin cicatricial pemphigoid. (18718187)
2008
22
Clinical response of severe mechanobullous epidermolysis bullosa acquisita to combined treatment with immunoadsorption and rituximab (anti-CD20 monoclonal antibodies). (17309999)
2007
23
A case of epidermolysis bullosa acquisita with autoantibody to anti-p200 pemphigoid antigen and exfoliative esophagitis. (16707891)
2006
24
Epidermolysis bullosa acquisita: diagnosis by fluorescence overlay antigen mapping and clinical response to high-dose intravenous immunoglobulin. (16309488)
2006
25
Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid. (15538734)
2004
26
Childhood epidermolysis bullosa acquisita with autoantibodies against all 3 structural domains of type VII collagen. (14988700)
2004
27
A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading. (15243536)
2004
28
Anti-epiligrin cicatricial pemphigoid and epidermolysis bullosa acquisita: differentiation by use of indirect immunofluorescence microscopy. (12664017)
2003
29
Epidermolysis bullosa acquisita in childhood. (12692360)
2003
30
Novel localised variant of canine epidermolysis bullosa acquisita. (10718593)
2000
31
Treatment of epidermolysis bullosa acquisita with mycophenolate mofetil and autologous keratinocyte grafting. (10583185)
1999
32
Epidermolysis bullosa acquisita exacerbated by systemic estrogen and progesterone treatment and pregnancy. (9146549)
1997
33
Linear IgA disease with clinical and immunopathological features of epidermolysis bullosa acquisita. (9263315)
1997
34
Bullous pemphigoid and epidermolysis bullosa acquisita. Differentiation by fluorescence overlay antigen mapping. (8629822)
1996
35
Epidermolysis bullosa acquisita: report of a case with comparison of immunogold electron microscopy using pre- and postembedding labelling. (8745903)
1996
36
Successful treatment of epidermolysis bullosa acquisita using intravenous immunoglobulins. (7772494)
1995
37
Laryngeal manifestations of epidermolysis bullosa acquisita. (7646856)
1995
38
Epidermolysis bullosa acquisita with oesophageal stenosis. (1390148)
1992
39
Epidermolysis bullosa acquisita and associated symptomatic esophageal webs. (1998368)
1991
40
Direct immunofluorescence studies of sodium chloride-separated skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. (2180996)
1990
41
The presence of intra-lamina lucida blister formation in epidermolysis bullosa acquisita: possible role of leukocytes. (2642510)
1989
42
Epidermolysis bullosa acquisita in childhood. Differentiation from hereditary epidermolysis bullosa. (2662910)
1989
43
Epidermal basement membrane alterations in epidermolysis bullosa acquisita. (3074092)
1988
44
Epidermolysis bullosa acquisita antigen: relationship between the collagenase-sensitive and -insensitive domains. (2828479)
1988
45
Severe ocular involvement in a patient with epidermolysis bullosa acquisita. (3819091)
1987
46
Ultrastructural and immuno-electron microscopic study in a case of epidermolysis bullosa acquisita. (7336921)
1981
47
Acidic glycosaminoglycans in cultured skin fibroblasts of a patient with epidermolysis bullosa acquisita. (7404577)
1980
48
Epidermolysis bullosa acquisita: a clinical disorder of varied etiologies. Two cases and a review of immunologic and other reported findings. (7005274)
1980
49
Vitamin E treatment of epidermolysis bullosa acquisita. (1022216)
1976
50
Epidermolysis bullosa acquisita. Report of three cases and review of all published cases. (4321800)
1971

Variations for Epidermolysis Bullosa Acquisita

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Expression for genes affiliated with Epidermolysis Bullosa Acquisita

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidermolysis Bullosa Acquisita

Search GEO for disease gene expression data for Epidermolysis Bullosa Acquisita.

Pathways for genes affiliated with Epidermolysis Bullosa Acquisita

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Sources:
50PathCards, 38NCBI BioSystems Database, 5Cell Signaling Technology, 55Reactome, 30KEGG, 60Thomson Reuters, 53QIAGEN, 54R&D Systems
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Pathways related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0COL17A1, ITGB4
29.5IL2RB, IL2RA, LAMC2
39.4CD79A, IL2RB, IL2RA
4
Show member pathways
9.2LAMA3, LAMC2, DST, ITGB4, COL17A1
5
Show member pathways
9.2LAMA3, LAMC2, DST, ITGB4, COL17A1
6
Show member pathways
9.2CSF2, IL2RB, IL2RA
7
Show member pathways
Type III interferon signaling38
9.2IL2RA, IL2RB, CSF2
8
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.1HLA-DRB1, IL2RA, IL2RB
9
Show member pathways
9.1IL2RB, IL2RA, HLA-DRB1
10
Show member pathways
Immune response IL 22 signaling pathway60
G protein signaling N RAS regulation pathway60
9.1IL2RB, IL2RA, HLA-DRB1
118.9LAMA3, LAMC2, ITGB4, IL2RA, IL2RB
128.9HLA-DRB1, IL2RA, CSF2
13
Show member pathways
Proteogylcan syndecan-mediated signaling events38
8.9ITGB4, TGFB1, LAMC2, LAMA3
14
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
8.9CD79A, CSF2, TGFB1
158.9TGFB1, IL2RA, IL2RB
168.8LAMA3, TGFB1, CSF2
178.8MATN1, TGFB1, LAMA3
18
Show member pathways
8.8HLA-DRB1, IL2RA, IL2RB, CD79A
19
Show member pathways
8.7IL2RB, IL2RA, ITGB4, TGFB1
208.6HLA-DRB1, TGFB1, IL2RA
218.6LAMA3, LAMC2, TGFB1, CSF2
22
Show member pathways
8.6LAMA3, LAMC2, SERPINH1, DST, ITGB4, COL7A1
23
Show member pathways
8.5CSF2, IL2RB, IL2RA, HLA-DRB1
248.5CSF2, TGFB1, HLA-DRB1
258.5CSF2, TGFB1, HLA-DRB1
26
Show member pathways
8.5HLA-DRB1, LAMA3, LAMC2, TGFB1
27
Show member pathways
8.4LAMA3, LAMC2, TGFB1, ITGB4, COL7A1, COL17A1
28
Show member pathways
8.3TGFB1, IL2RA, IL2RB, CSF2
29
Show member pathways
8.1CD79A, IL2RA, ITGB4, TGFB1, HLA-DRB1
30
Show member pathways
8.1TGFB1, ITGB4, IL2RA, IL2RB, CSF2
317.7HLA-DRB1, TGFB1, IL2RA, IL2RB, CSF2
32
Show member pathways
7.7LAMA3, LAMC2, TGFB1, ITGB4, IL2RA, COL7A1
33
Show member pathways
7.2MATN1, LAMA3, LAMC2, TGFB1, SERPINH1, DST
34
Show member pathways
7.1LAMA3, LAMC2, TGFB1, ITGB4, IL2RA, IL2RB

Compounds for genes affiliated with Epidermolysis Bullosa Acquisita

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Sources:
45Novoseek, 51PharmGKB, 11DrugBank, 3BitterDB, 29IUPHAR, 24HMDB, 61Tocris Bioscience
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Compounds related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show top 50)    (show all 79)
idCompoundScoreTop Affiliating Genes
1mizoribine4510.1CD79A, IL2RA
2lentinan4510.1IL2RB, IL2RA
3mycophenolate4510.1IL2RB, IL2RA
4thymoglobulin4510.0IL2RB, IL2RA
5gluten4510.0IL2RA, CD79A
6denileukin diftitox45 51 1112.0IL2RA, IL2RB
7kalinin459.9LAMA3, LAMC2, DST, ITGB4
8con a459.8IL2RA, IL2RB, CD79A
9mycophenolate mofetil45 51 1111.8CD79A, IL2RB, IL2RA
10gold459.8LAMC2, DST, IL2RB, COL17A1
11delta9-tetrahydrocannabinol459.6IL2RB, IL2RA
12azathioprine45 3 51 1112.6IL2RA, IL2RB, CD79A
13pentoxifylline45 1110.5CSF2, IL2RB, IL2RA
14ifn-alpha459.5IL2RA, IL2RB, CSF2
15okt3459.4CD79A, CSF2, IL2RB, IL2RA
16neopterin459.3IL2RA, IL2RB, CSF2, CD79A
17betacarotene459.3TGFB1, IL2RA, CD79A
18pmma459.3CD79A, CSF2, TGFB1
19theophylline45 29 24 1112.3CD79A, IL2RA, TGFB1
20alginate459.3CD79A, MATN1, TGFB1
21erythromycin45 3 51 1112.2TGFB1, IL2RA, IL2RB
22prednisolone45 29 1111.1IL2RA, IL2RB, CD79A
23norepinephrine45 24 1111.1CD79A, CSF2, IL2RB, IL2RA
24procollagen459.0MATN1, SERPINH1, TGFB1
25tacrolimus45 51 1111.0TGFB1, IL2RA, IL2RB, CD79A
26bleomycin45 1110.0TGFB1, IL2RA, CSF2
27methacholine45 51 1110.9TGFB1, IL2RB, CSF2, CD79A
28verapamil45 29 51 24 1112.9IL2RB, IL2RA, TGFB1
291,25 dihydroxy vitamin d3458.8CSF2, IL2RB, TGFB1
3012-o-tetradecanoylphorbol 13-acetate458.8CSF2, IL2RB, DST, TGFB1
31il 10458.8TGFB1, IL2RA, IL2RB, CSF2
32nifedipine45 29 51 1111.8TGFB1, IL2RA, IL2RB, CSF2
33vitamin d458.7TGFB1, IL2RA, CSF2, CD79A
34paraffin458.7TGFB1, DST, IL2RA, CD79A
35rantes458.7TGFB1, IL2RA, IL2RB, CSF2
36arginine458.7CD79A, COL7A1, IL2RB, IL2RA, HLA-DRB1
37cycloheximide458.6TGFB1, DST, IL2RB, COL17A1, CSF2
38ivig458.6CD79A, CSF2, IL2RB, IL2RA, DSG1, FCGRT
39aspirin45 51 29 2411.5TGFB1, IL2RA, IL2RB, CSF2, CD79A
40polysaccharide458.5TGFB1, IL2RA, IL2RB, CSF2, CD79A
41histamine45 29 2410.5TGFB1, IL2RA, IL2RB, CSF2, CD79A
42pge2458.5TGFB1, IL2RA, IL2RB, CSF2, CD79A
43rituximab45 51 1110.5TGFB1, DSG1, IL2RA, CSF2, CD79A
44methotrexate51 45 1110.4CD79A, IL2RB, IL2RA, TGFB1, HLA-DRB1
45dexamethasone45 51 29 1111.3TGFB1, IL2RA, IL2RB, CSF2, CD79A
46cyclosporin a45 29 6110.2TGFB1, SERPINH1, IL2RA, IL2RB, CSF2, CD79A
47vegf458.2TGFB1, SERPINH1, IL2RA, IL2RB, CSF2, CD79A
48serine458.1TGFB1, SERPINH1, DSG1, ITGB4, IL2RB, COL7A1
49tyrosine458.1HLA-DRB1, SERPINH1, ITGB4, IL2RA, IL2RB, COL17A1
50retinoic acid45 248.7TGFB1, DSG1, ITGB4, IL2RB, MATN1, CSF2

GO Terms for genes affiliated with Epidermolysis Bullosa Acquisita

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16Gene Ontology
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Cellular components related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1laminin-5 complexGO:00561010.1LAMA3, LAMC2
2basal plasma membraneGO:00992510.0ITGB4, DST
3hemidesmosomeGO:03005610.0DST, ITGB4, COL17A1
4cell leading edgeGO:0312529.7ITGB4, DST
5endoplasmic reticulum lumenGO:0057889.5COL17A1, COL7A1, SERPINH1
6basement membraneGO:0056049.2COL17A1, COL7A1, ITGB4, DST, LAD1, LAMA3
7external side of plasma membraneGO:0098979.0CD79A, IL2RB, IL2RA, HLA-DRB1
8extracellular spaceGO:0056158.2LAMC2, TGFB1, SERPINH1, COL7A1, CSF2
9extracellular regionGO:0055767.7LAMA3, LAMC2, TGFB1, COL7A1, COL17A1, MATN1
10plasma membraneGO:0058866.8HLA-DRB1, FCGRT, TGFB1, DSG1, ITGB4, IL2RA

Biological processes related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1cell motilityGO:0488709.9DST, ITGB4
2cell junction assemblyGO:0343299.8COL17A1, ITGB4, LAMC2, LAMA3
3epidermis developmentGO:0085449.7LAMA3, LAMC2, COL7A1, COL17A1
4extracellular matrix disassemblyGO:0226179.6LAMA3, LAMC2, COL7A1, COL17A1
5hemidesmosome assemblyGO:0315819.5LAMA3, LAMC2, DST, ITGB4, COL17A1
6inflammatory response to antigenic stimulusGO:0024379.4IL2RA, HLA-DRB1
7cell adhesionGO:0071559.3LAMA3, LAMC2, DST, ITGB4, COL7A1
8response to woundingGO:0096119.3ITGB4, DST, TGFB1
9negative regulation of immune responseGO:0507779.3IL2RA, TGFB1
10response to progesteroneGO:0325709.2DSG1, TGFB1
11myeloid dendritic cell differentiationGO:0430118.8CSF2, TGFB1
12negative regulation of T cell proliferationGO:0421308.8IL2RA, TGFB1, HLA-DRB1
13immune responseGO:0069558.7HLA-DRB1, FCGRT, IL2RA, CSF2
14extracellular matrix organizationGO:0301987.5MATN1, LAMA3, LAMC2, TGFB1, SERPINH1, DST

Molecular functions related to Epidermolysis Bullosa Acquisita according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1interleukin-2 bindingGO:0199769.7IL2RB, IL2RA
2interleukin-2 receptor activityGO:0049119.4IL2RB, IL2RA

Products for genes affiliated with Epidermolysis Bullosa Acquisita

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Sources for Epidermolysis Bullosa Acquisita

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet