MCID: EPD004
MIFTS: 23

Epidermolytic Acanthoma malady

Skin category

Summaries for Epidermolytic Acanthoma

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Epidermolytic acanthomas are a cutaneous condition characterized by discrete keratotic papules in adults. more...

MalaCards: Epidermolytic Acanthoma is related to acanthoma and porokeratosis. An important gene associated with Epidermolytic Acanthoma is KRT1 (keratin 1), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds dithranol and sodium dodecylsulfate have been mentioned in the context of this disorder. Related mouse phenotype integument.

Aliases & Classifications for Epidermolytic Acanthoma

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 40NCIt
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Aliases & Descriptions:

epidermolytic acanthoma 8 10 61


External Ids:

Disease Ontology8 DOID:4323
NCIt40 C27516

Related Diseases for Epidermolytic Acanthoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Epidermolytic Acanthoma:



Diseases related to epidermolytic acanthoma

Clinical Features for Epidermolytic Acanthoma

Drugs & Therapeutics for Epidermolytic Acanthoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Epidermolytic Acanthoma

Drug clinical trials:

Search ClinicalTrials for Epidermolytic Acanthoma

Search NIH Clinical Center for Epidermolytic Acanthoma

Search CenterWatch for Epidermolytic Acanthoma

Genetic Tests for Epidermolytic Acanthoma

Anatomical Context for Epidermolytic Acanthoma

Animal Models for Epidermolytic Acanthoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Epidermolytic Acanthoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.5KRT10, KRT1, KRT16

Publications for Epidermolytic Acanthoma

Sources:
51PubMed
See all sources

Articles related to Epidermolytic Acanthoma:

(show all 20)
idTitleAuthorsYear
1
Disseminated epidermolytic acanthoma with partial response to calcipotriol ointment. (23083445)
2013
2
Solitary epidermolytic acanthoma. (23710687)
2013
3
Isolated epidermolytic acanthoma in a renal transplant recipient. (21909223)
2011
4
Solitary epidermolytic acanthoma: a clinical and histopathological study. (20553361)
2011
5
Epidermolytic acanthoma of the scrotum: A rare mimicker of condyloma acuminatum. (21272497)
2011
6
Linear epidermolytic acanthoma of vulva: an unusual presentation. (20061731)
2010
7
Linear epidermolytic acanthoma or adult-onset verrucous epidermal nevus? (20827001)
2010
8
Verruciform xanthoma in close association with isolated epidermolytic acanthoma: a case report and review of the Japanese dermatological literature. (16043921)
2005
9
Disseminated epidermolytic acanthoma probably related to trauma. (10583127)
1999
10
Epidermolytic acanthomas: clinical characteristics and immunohistochemical features. (9185908)
1997
11
Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient. (8537558)
1995
12
Isolated dyskeratotic acanthoma. A variant of isolated epidermolytic acanthoma. (7695013)
1995
13
Disseminated epidermolytic acanthoma. (8434736)
1993
14
Epidermolytic acanthoma does not contain human papillomavirus DNA. (1649846)
1991
15
Vulvar localisation of epidermolytic acanthoma. A light- and electron-microscopic study. (3743846)
1986
16
Disseminated epidermolytic acanthoma revealed by PUVA. (3770261)
1986
17
Disseminated epidermolytic acanthoma. (500873)
1979
18
Isolated epidermolytic acanthoma. A histological study. (478041)
1979
19
Disseminated epidermolytic acanthoma. Nonsystematized multiple verrucoid lesions showing granular degeneration. (4127475)
1973
20
Isolated epidermolytic acanthoma. A solitary tumor showing granular degeneration. (5413257)
1970

Genetic Variations for Epidermolytic Acanthoma

Expression for genes affiliated with Epidermolytic Acanthoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Epidermolytic Acanthoma

Search GEO for disease gene expression data for Epidermolytic Acanthoma.

Pathways for genes affiliated with Epidermolytic Acanthoma

Sources:
12EMD Millipore
See all sources

Pathways related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3KRT1, KRT16

Compounds for genes affiliated with Epidermolytic Acanthoma

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB
See all sources

Compounds related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1dithranol459.4KRT10, KRT16
2sodium dodecylsulfate459.4KRT16, KRT1
3calcipotriol45 60 29 1112.4KRT10, KRT16
4tazarotene45 1110.3KRT1, KRT10
5isoleucine459.2KRT10, KRT1
6hematoxylin459.2KRT10, KRT1
71,25 dihydroxy vitamin d3459.1KRT10, KRT16
8bromodeoxyuridine458.9KRT10, KRT1
9calcitriol45 60 11 2411.8KRT16, KRT10
10isotretinoin45 119.8KRT10, KRT1, KRT16
11retinoid458.8KRT10, KRT1, KRT16
12paraffin458.7KRT16, KRT1, KRT10
13proline458.7KRT10, KRT1, KRT16
14steroid458.7KRT16, KRT1, KRT10
15retinoic acid45 249.6KRT10, KRT1, KRT16
16serine458.5KRT10, KRT1, KRT16

GO Terms for genes affiliated with Epidermolytic Acanthoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.1KRT10, KRT16
2keratin filamentGO:0450958.7KRT10, KRT1

Products for genes affiliated with Epidermolytic Acanthoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidermolytic Acanthoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet