MCID: EPD004
MIFTS: 30

Epidermolytic Acanthoma malady

Cancer diseases, Skin diseases categories

Summaries for Epidermolytic Acanthoma

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66Wikipedia, 34MalaCards
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Wikipedia:66 Epidermolytic acanthomas are a cutaneous condition characterized by discrete keratotic papules in adults. more...

MalaCards: Epidermolytic Acanthoma is related to acanthoma and porokeratosis. An important gene associated with Epidermolytic Acanthoma is KRT10 (keratin 10), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds tazarotene and isoleucine have been mentioned in the context of this disorder. Related mouse phenotypes are growth/size/body and integument.

Aliases & Classifications for Epidermolytic Acanthoma

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases


Aliases & Descriptions:

epidermolytic acanthoma 9 11 63


External Ids:

Disease Ontology9 DOID:4323
NCIt41 C27516

Related Diseases for Epidermolytic Acanthoma

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Epidermolytic Acanthoma:



Diseases related to epidermolytic acanthoma

Symptoms for Epidermolytic Acanthoma

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Drugs & Therapeutics for Epidermolytic Acanthoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Epidermolytic Acanthoma

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Anatomical Context for Epidermolytic Acanthoma

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Animal Models for Epidermolytic Acanthoma or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Epidermolytic Acanthoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.5KRT16, KRT1, KRT10
2MP:00107718.2KRT16, KRT1, KRT10

Publications for Epidermolytic Acanthoma

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53PubMed
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Articles related to Epidermolytic Acanthoma:

(show all 20)
idTitleAuthorsYear
1
Disseminated epidermolytic acanthoma with partial response to calcipotriol ointment. (23083445)
2013
2
Solitary epidermolytic acanthoma. (23710687)
2013
3
Isolated epidermolytic acanthoma in a renal transplant recipient. (21909223)
2011
4
Solitary epidermolytic acanthoma: a clinical and histopathological study. (20553361)
2011
5
Epidermolytic acanthoma of the scrotum: A rare mimicker of condyloma acuminatum. (21272497)
2011
6
Linear epidermolytic acanthoma of vulva: an unusual presentation. (20061731)
2010
7
Linear epidermolytic acanthoma or adult-onset verrucous epidermal nevus? (20827001)
2010
8
Verruciform xanthoma in close association with isolated epidermolytic acanthoma: a case report and review of the Japanese dermatological literature. (16043921)
2005
9
Disseminated epidermolytic acanthoma probably related to trauma. (10583127)
1999
10
Epidermolytic acanthomas: clinical characteristics and immunohistochemical features. (9185908)
1997
11
Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient. (8537558)
1995
12
Isolated dyskeratotic acanthoma. A variant of isolated epidermolytic acanthoma. (7695013)
1995
13
Disseminated epidermolytic acanthoma. (8434736)
1993
14
Epidermolytic acanthoma does not contain human papillomavirus DNA. (1649846)
1991
15
Vulvar localisation of epidermolytic acanthoma. A light- and electron-microscopic study. (3743846)
1986
16
Disseminated epidermolytic acanthoma revealed by PUVA. (3770261)
1986
17
Disseminated epidermolytic acanthoma. (500873)
1979
18
Isolated epidermolytic acanthoma. A histological study. (478041)
1979
19
Disseminated epidermolytic acanthoma. Nonsystematized multiple verrucoid lesions showing granular degeneration. (4127475)
1973
20
Isolated epidermolytic acanthoma. A solitary tumor showing granular degeneration. (5413257)
1970

Variations for Epidermolytic Acanthoma

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Expression for genes affiliated with Epidermolytic Acanthoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidermolytic Acanthoma

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Pathways for genes affiliated with Epidermolytic Acanthoma

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51PathCards, 61Thomson Reuters
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Pathways related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT16, KRT1

Compounds for genes affiliated with Epidermolytic Acanthoma

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Sources:
46Novoseek, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 25HMDB
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Compounds related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1tazarotene46 1210.6KRT10, KRT1
2isoleucine469.5KRT1, KRT10
3hematoxylin469.5KRT1, KRT10
4dithranol469.3KRT16, KRT10
5calcipotriol46 62 30 1212.3KRT16, KRT10
6bromodeoxyuridine469.2KRT1, KRT10
7sodium dodecylsulfate469.2KRT1, KRT16
81,25 dihydroxy vitamin d3469.0KRT16, KRT10
9calcitriol46 62 25 1212.0KRT16, KRT10
10isotretinoin46 129.8KRT16, KRT1, KRT10
11retinoid468.8KRT16, KRT1, KRT10
12paraffin468.8KRT16, KRT1, KRT10
13proline468.7KRT10, KRT1, KRT16
14steroid468.7KRT10, KRT1, KRT16
15retinoic acid46 259.6KRT16, KRT1, KRT10
16serine468.2KRT10, KRT1, KRT16

GO Terms for genes affiliated with Epidermolytic Acanthoma

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17Gene Ontology
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Cellular components related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.2KRT1, KRT10
2intermediate filamentGO:0058828.7KRT16, KRT10
3extracellular vesicular exosomeGO:0700628.5KRT16, KRT1, KRT10

Products for genes affiliated with Epidermolytic Acanthoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidermolytic Acanthoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet