MCID: EPD004
MIFTS: 30

Epidermolytic Acanthoma malady

Cancer diseases, Skin diseases categories
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Summaries for Epidermolytic Acanthoma

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Epidermolytic acanthomas are a cutaneous condition characterized by discrete keratotic papules in adults. more...

MalaCards: Epidermolytic Acanthoma is related to acanthoma and porokeratosis. An important gene associated with Epidermolytic Acanthoma is KRT10 (keratin 10), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds tazarotene and isoleucine have been mentioned in the context of this disorder. Related mouse phenotypes are growth/size/body and integument.

Aliases & Classifications for Epidermolytic Acanthoma

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8Disease Ontology, 10DISEASES, 62UMLS, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases


Aliases & Descriptions:

epidermolytic acanthoma 8 10 62


External Ids:

Disease Ontology8 DOID:4323
NCIt40 C27516

Related Diseases for Epidermolytic Acanthoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Epidermolytic Acanthoma:



Diseases related to epidermolytic acanthoma

Symptoms for Epidermolytic Acanthoma

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Drugs & Therapeutics for Epidermolytic Acanthoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Epidermolytic Acanthoma

Genetic Tests for Epidermolytic Acanthoma

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Anatomical Context for Epidermolytic Acanthoma

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Animal Models for Epidermolytic Acanthoma or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Epidermolytic Acanthoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.5KRT16, KRT1, KRT10
2MP:00107718.2KRT16, KRT1, KRT10

Publications for Epidermolytic Acanthoma

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52PubMed
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Articles related to Epidermolytic Acanthoma:

(show all 20)
idTitleAuthorsYear
1
Disseminated epidermolytic acanthoma with partial response to calcipotriol ointment. (23083445)
2013
2
Solitary epidermolytic acanthoma. (23710687)
2013
3
Isolated epidermolytic acanthoma in a renal transplant recipient. (21909223)
2011
4
Solitary epidermolytic acanthoma: a clinical and histopathological study. (20553361)
2011
5
Epidermolytic acanthoma of the scrotum: A rare mimicker of condyloma acuminatum. (21272497)
2011
6
Linear epidermolytic acanthoma of vulva: an unusual presentation. (20061731)
2010
7
Linear epidermolytic acanthoma or adult-onset verrucous epidermal nevus? (20827001)
2010
8
Verruciform xanthoma in close association with isolated epidermolytic acanthoma: a case report and review of the Japanese dermatological literature. (16043921)
2005
9
Disseminated epidermolytic acanthoma probably related to trauma. (10583127)
1999
10
Epidermolytic acanthomas: clinical characteristics and immunohistochemical features. (9185908)
1997
11
Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient. (8537558)
1995
12
Isolated dyskeratotic acanthoma. A variant of isolated epidermolytic acanthoma. (7695013)
1995
13
Disseminated epidermolytic acanthoma. (8434736)
1993
14
Epidermolytic acanthoma does not contain human papillomavirus DNA. (1649846)
1991
15
Vulvar localisation of epidermolytic acanthoma. A light- and electron-microscopic study. (3743846)
1986
16
Disseminated epidermolytic acanthoma revealed by PUVA. (3770261)
1986
17
Disseminated epidermolytic acanthoma. (500873)
1979
18
Isolated epidermolytic acanthoma. A histological study. (478041)
1979
19
Disseminated epidermolytic acanthoma. Nonsystematized multiple verrucoid lesions showing granular degeneration. (4127475)
1973
20
Isolated epidermolytic acanthoma. A solitary tumor showing granular degeneration. (5413257)
1970

Variations for Epidermolytic Acanthoma

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Expression for genes affiliated with Epidermolytic Acanthoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epidermolytic Acanthoma

Search GEO for disease gene expression data for Epidermolytic Acanthoma.

Pathways for genes affiliated with Epidermolytic Acanthoma

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50PathCards, 60Thomson Reuters
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Pathways related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT16, KRT1

Compounds for genes affiliated with Epidermolytic Acanthoma

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Sources:
45Novoseek, 11DrugBank, 61Tocris Bioscience, 29IUPHAR, 24HMDB
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Compounds related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1tazarotene45 1110.6KRT10, KRT1
2isoleucine459.5KRT1, KRT10
3hematoxylin459.5KRT1, KRT10
4dithranol459.3KRT16, KRT10
5calcipotriol45 61 29 1112.3KRT16, KRT10
6bromodeoxyuridine459.2KRT1, KRT10
7sodium dodecylsulfate459.2KRT1, KRT16
81,25 dihydroxy vitamin d3459.0KRT16, KRT10
9calcitriol45 61 24 1112.0KRT16, KRT10
10isotretinoin45 119.8KRT16, KRT1, KRT10
11retinoid458.8KRT16, KRT1, KRT10
12paraffin458.8KRT16, KRT1, KRT10
13proline458.7KRT10, KRT1, KRT16
14steroid458.7KRT10, KRT1, KRT16
15retinoic acid45 249.6KRT16, KRT1, KRT10
16serine458.2KRT10, KRT1, KRT16

GO Terms for genes affiliated with Epidermolytic Acanthoma

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16Gene Ontology
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Cellular components related to Epidermolytic Acanthoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.2KRT1, KRT10
2intermediate filamentGO:0058828.7KRT16, KRT10
3extracellular vesicular exosomeGO:0700628.5KRT16, KRT1, KRT10

Products for genes affiliated with Epidermolytic Acanthoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epidermolytic Acanthoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet