MCID: EPL164
MIFTS: 65

Epilepsy

Categories: Neuronal diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Epilepsy

MalaCards integrated aliases for Epilepsy:

Name: Epilepsy 12 24 51 52 41 3 42 14 69
Epileptic Syndrome 12
Epilepsy Syndrome 12

Classifications:



Summaries for Epilepsy

NINDS : 51 The epilepsies are a spectrum of brain disorders ranging from severe, life-threatening and disabling, to ones that are much more benign. In epilepsy, the normal pattern of neuronal activity becomes disturbed, causing strange sensations, emotions, and behavior or sometimes convulsions, muscle spasms, and loss of consciousness. The epilepsies have many possible causes and there are several types of seizures. Anything that disturbs the normal pattern of neuron activity—from illness to brain damage to abnormal brain development—can lead to seizures. Epilepsy may develop because of an abnormality in brain wiring, an imbalance of nerve signaling chemicals called neurotransmitters, changes in important features of brain cells called channels, or some combination of these and other factors. Having a single seizure as the result of a high fever (called febrile seizure) or head injury does not necessarily mean that a person has epilepsy. Only when a person has had two or more seizures is he or she considered to have epilepsy. A measurement of electrical activity in the brain and brain scans such as magnetic resonance imaging or computed tomography are common diagnostic tests for epilepsy.

MalaCards based summary : Epilepsy, also known as epileptic syndrome, is related to epilepsy, juvenile absence 1 and idiopathic generalized epilepsy, and has symptoms including back pain, headache and pain. An important gene associated with Epilepsy is EPM2A (EPM2A, Laforin Glucan Phosphatase), and among its related pathways/superpathways are Circadian entrainment and Transmission across Chemical Synapses. The drugs Lamotrigine and Valproic Acid have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and testes, and related phenotypes are Resistant to vaccinia virus (VACV-A4L) infection and behavior/neurological

Disease Ontology : 12 A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.

MedlinePlus : 41 epilepsy is a brain disorder that causes people to have recurring seizures. the seizures happen when clusters of nerve cells, or neurons, in the brain send out the wrong signals. people may have strange sensations and emotions or behave strangely. they may have violent muscle spasms or lose consciousness. epilepsy has many possible causes, including illness, brain injury, and abnormal brain development. in many cases, the cause is unknown. doctors use brain scans and other tests to diagnose epilepsy. it is important to start treatment right away. there is no cure for epilepsy, but medicines can control seizures for most people. when medicines are not working well, surgery or implanted devices such as vagus nerve stimulators may help. special diets can help some children with epilepsy. nih: national institute of neurological disorders and stroke

Wikipedia : 72 Epilepsy is a group of neurological disorders characterized by epileptic seizures. Epileptic seizures... more...

Related Diseases for Epilepsy

Diseases in the Epilepsy family:

Benign Familial Infantile Epilepsy Depdc5-Related Epilepsy

Diseases related to Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 977)
id Related Disease Score Top Affiliating Genes
1 epilepsy, juvenile absence 1 34.3 CACNB4 EFHC1
2 idiopathic generalized epilepsy 34.0 LGI1 POLG SCN1A
3 epilepsy, nocturnal frontal lobe, 3 34.0 CHRNA4 CHRNB2
4 epilepsy, generalized, with febrile seizures plus, type 5 33.5 CACNB4 CHRNA4 CSTB EFHC1 GABRA1 GABRB3
5 early onset absence epilepsy 33.2 CACNA1H EFHC1 GABRA1 GABRB3 GABRG2 GRIN2A
6 headache 31.0 CHRNA4 GABRG2 SCN1A SCN1B
7 neuronal migration disorders 30.9 CSTB EPM2A NHLRC1 SLC2A1
8 hyperekplexia 30.2 CHRNA2 CHRNA4 CHRNB2
9 personality disorder 30.2 CHRNA4 GRIN2A RELN
10 gingival overgrowth 30.1 CHRNA4 CSTB EPM2A GABRG2 SCN1A SCN1B
11 benign epilepsy with centrotemporal spikes 12.2
12 generalized epilepsy with febrile seizures plus 12.1
13 childhood absence epilepsy 12.1
14 epilepsy-aphasia spectrum 12.1
15 epilepsy, progressive myoclonic 2b 12.1
16 photosensitive epilepsy 12.1
17 epilepsy, pyridoxine-dependent 12.1
18 temporal lobe epilepsy 12.1
19 benign familial neonatal epilepsy 12.0
20 epilepsy, focal, with speech disorder and with or without mental retardation 12.0
21 progressive myoclonus epilepsy 12.0
22 autosomal dominant nocturnal frontal lobe epilepsy 12.0
23 focal epilepsy 12.0
24 epilepsy, progressive myoclonic 3, with or without intracellular inclusions 12.0
25 benign familial infantile epilepsy 12.0
26 myoclonic epilepsy associated with ragged-red fibers 12.0
27 ceroid lipofuscinosis, neuronal, 8, northern epilepsy variant 12.0
28 myoclonic astatic epilepsy 12.0
29 juvenile absence epilepsy 12.0
30 autosomal dominant partial epilepsy with auditory features 12.0
31 spinal muscular atrophy with progressive myoclonic epilepsy 12.0
32 progressive myoclonus epilepsy, lafora type 12.0
33 epilepsy, juvenile myoclonic 5 12.0
34 epilepsy, progressive myoclonic 7 12.0
35 epilepsy, idiopathic generalized 11 12.0
36 epilepsy, familial focal, with variable foci 1 11.9
37 prickle1-related progressive myoclonus epilepsy with ataxia 11.9
38 myoclonic epilepsy, infantile, familial 11.9
39 epilepsy, progressive myoclonic 6 11.9
40 epilepsy, progressive myoclonic, 9 11.9
41 epilepsy, progressive myoclonic, 8 11.9
42 epilepsy, familial temporal lobe, 1 11.9
43 centrotemporal epilepsy 11.9
44 pyridoxal 5'-phosphate-dependent epilepsy 11.9
45 epilepsy, familial temporal lobe, 2 11.9
46 febrile infection-related epilepsy syndrome 11.9
47 epilepsy, childhood absence 6 11.9
48 myoclonic-atonic epilepsy 11.9
49 epilepsy, idiopathic generalized 9 11.9
50 epilepsy, nocturnal frontal lobe, 1 11.9

Graphical network of the top 20 diseases related to Epilepsy:



Diseases related to Epilepsy

Symptoms & Phenotypes for Epilepsy

UMLS symptoms related to Epilepsy:


back pain, headache, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, non-epileptic convulsion, seizures, focal, sleeplessness

GenomeRNAi Phenotypes related to Epilepsy according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Resistant to vaccinia virus (VACV-A4L) infection GR00351-A-1 9.23 CACNB4 CSTB EFHC1 GABRA1 GRIN2A NHLRC1

MGI Mouse Phenotypes related to Epilepsy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.36 CACNA1H CACNB4 CHRNA4 CHRNB2 CLN8 CSTB
2 growth/size/body region MP:0005378 10.21 CACNA1H CACNB4 CHRNB2 CSTB EPM2A GABRA1
3 mortality/aging MP:0010768 10.17 GABRG2 LGI1 POLG RELN SCN1A SCN1B
4 nervous system MP:0003631 10.16 LGI1 NHLRC1 POLG RELN SCN1A SCN1B
5 muscle MP:0005369 9.96 CSTB EFHC1 EPM2A GABRA1 NHLRC1 POLG
6 no phenotypic analysis MP:0003012 9.56 CHRNA4 CSTB GABRA1 GABRB3 NHLRC1 POLG
7 reproductive system MP:0005389 9.23 CACNB4 CLN8 GABRA1 GABRB3 GABRG2 POLG

Drugs & Therapeutics for Epilepsy

Drugs for Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 542)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lamotrigine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 84057-84-1 3878
2
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 99-66-1 3121
3
Topiramate Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 97240-79-4 5284627
4
Acetazolamide Approved, Vet_approved Phase 4,Phase 2,Phase 3 59-66-5 1986
5
Carbamazepine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 298-46-4 2554
6
Clobazam Approved, Illicit Phase 4,Phase 3,Phase 2 22316-47-8 2789
7
Clonazepam Approved, Illicit Phase 4,Phase 3,Phase 2 1622-61-3 2802
8
Ethosuximide Approved Phase 4,Phase 3 77-67-8 3291
9
Felbamate Approved Phase 4 25451-15-4 3331
10
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 60142-96-3 3446
11
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
12
Nitrazepam Approved Phase 4,Phase 2 146-22-5 4506
13
Oxcarbazepine Approved Phase 4,Phase 3,Phase 2,Phase 1 28721-07-5 34312
14
Phenobarbital Approved Phase 4,Phase 3,Phase 2,Phase 1 50-06-6 4763
15
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-41-0 1775
16
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
17
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1 148553-50-8 5486971
18
Tiagabine Approved Phase 4,Phase 1 115103-54-3 60648
19
Vigabatrin Approved Phase 4,Phase 3,Phase 2 68506-86-5, 60643-86-9 5665
20
Zonisamide Approved, Investigational Phase 4,Phase 3 68291-97-4 5734
21 Piracetam Approved Phase 4,Phase 3,Phase 2,Phase 1 7491-74-9
22
Milnacipran Approved Phase 4 92623-85-3 65833
23
Lacosamide Approved Phase 4,Phase 3,Phase 2,Phase 1 860352-01-8, 175481-36-4 219078
24
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
25
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 57-27-2 5288826
26
Benzocaine Approved Phase 4,Phase 2,Phase 3 1994-09-7, 94-09-7 2337
27
Eslicarbazepine acetate Approved Phase 4,Phase 3,Phase 2,Phase 1 75970-99-9, 236395-14-5 123618
28
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 2078-54-8 4943
29
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
30
Acetylcholine Approved Phase 4,Phase 2 51-84-3 187
31
Lorazepam Approved Phase 4,Phase 3,Phase 2,Phase 1 846-49-1 3958
32
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
33
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 159351-69-6 6442177
34
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
35
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53123-88-9 5284616 6436030 46835353
36
Amitriptyline Approved Phase 4,Phase 3 50-48-6 2160
37
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
38
Levonorgestrel Approved, Investigational Phase 4,Phase 1 797-63-7, 17489-40-6 13109
39
Citalopram Approved Phase 4 59729-33-8 2771
40
Clevidipine Approved Phase 4 167221-71-8
41
Hydralazine Approved Phase 4 86-54-4 3637
42
Labetalol Approved Phase 4 36894-69-6 3869
43
Sertraline Approved Phase 4,Phase 3 79617-96-2 68617
44
Acetaminophen Approved Phase 4 103-90-2 1983
45
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
46
Ibuprofen Approved Phase 4 15687-27-1 3672
47
Fosphenytoin Approved Phase 4,Phase 3,Phase 2,Phase 1 93390-81-9 56339
48
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
49
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
50
Bupropion Approved Phase 4,Phase 3 34841-39-9, 34911-55-2 444

Interventional clinical trials:

(show top 50) (show all 1539)

id Name Status NCT ID Phase Drugs
1 The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy Unknown status NCT00647322 Phase 4
2 Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy Unknown status NCT00454935 Phase 4
3 Hormone Profiles in Adults With Newly Diagnosed Epilepsy Unknown status NCT00137709 Phase 4 Sodium valproate;Lamotrigine
4 Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational Study Unknown status NCT00956696 Phase 4 topiramate
5 Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy Unknown status NCT00552526 Phase 4 Antiepileptic drug (AED)
6 Study to Improve the Treatment of Epilepsy (SITE) Unknown status NCT00133081 Phase 4 All registered antiepileptic drugs
7 BEEP Follow Up: Evaluation of Repeatability of Lamotrigine Pharmacokinetics in Epileptic Patients Unknown status NCT02404168 Phase 4 lamotrigine (brand Lamictal);lamotrigine (generic Teva)
8 Compare Tolerability of an Overnight Switch to Gradual Switch Between Two Different Forms of Depakote Unknown status NCT00312676 Phase 4
9 Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients Unknown status NCT00132223 Phase 4 Contrast agent
10 A Trial of Generic Substitution of Antiepileptic Drugs Unknown status NCT02429596 Phase 4 Experimental
11 Levetiracetam Treatment of Children With Subclinical Sleep-Activated Epileptiform Activity (SSEA) Unknown status NCT00393614 Phase 4 levetiracetam
12 Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects Unknown status NCT01370486 Phase 4 melatonin;placebo
13 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
14 Clinical Study of Xingnaojing for the Treatment of Convulsive Diseases Unknown status NCT00796380 Phase 4 Xingnaojing
15 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4 Use of prophylactic anticonvulsants (valproate, clonazepam);Control group
16 Preventive Treatment of Episodic and Chronic Migraine Unknown status NCT01319825 Phase 4 milnacipran
17 Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old. Unknown status NCT01478035 Phase 4 Phenytoin;placebo
18 Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage - Pilot Study Unknown status NCT01935908 Phase 4 levetiracetam
19 Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies Completed NCT00896987 Phase 4 lamotrigine (Lamictal);Carbamazepine (Tegretol)
20 Study on Migraine and Headache in Epileptic Patients Completed NCT00642564 Phase 4
21 Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Single-Dose 6-Period Replicate Design (EQUIGEN Single-Dose Study) Completed NCT01733394 Phase 4 Lamotrigine Generic "A" Lamotrigine Generic "B" Lamotrigine "Brand";lamotrigine
22 Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Chronic-Dose 4-Period Replicate Design Completed NCT01713777 Phase 4 Lamotrigine Generic "A";Lamotrigine generic "B"
23 Standardized Educational Plan for Epilepsy Patients With Comorbidities Completed NCT01804322 Phase 4
24 RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy Completed NCT00564915 Phase 4
25 Cognitive and Behavioral Effects of Lacosamide Completed NCT01175954 Phase 4 Lacosamide;Lacosamide
26 Valproate Dose Reduction and Its Clinical Evaluation by Introducing Lamotrigine in Japanese Women With Epilepsy - Single Arm, Multicenter, and Open-label Study - Completed NCT02100644 Phase 4 Lamotrigine tablets 25/100 mg
27 Levetiracetam for Benign Rolandic Epilepsy Completed NCT00181116 Phase 4 Levetiracetam
28 Measurement Of Serum Levels Of Two Antiepileptic Drugs During Conversion In Patients With Epilepsy Completed NCT00043914 Phase 4 lamotrigine
29 Safety and Efficacy of Topamax Versus Carbamazepine in Benign Rolandic Epilepsy Completed NCT00216567 Phase 4 topamax
30 Compliance With Once-Daily Divalproex Extended-Release Tablets (Depakote-ER) Versus Multiple-Daily Dose Valproic Acid Capsules (Depakene) in Epilepsy: Completed NCT00356018 Phase 4
31 Methylphenidate Treatment of Attention Deficits in Epilepsy Completed NCT02178995 Phase 4 Methylphenidate
32 Determine Effects of Adjunctive Levetiracetam on Sleep Architecture in Adults With Partial Onset Epilepsy. Completed NCT00245713 Phase 4 levetiracetam
33 Heart Rate Changes During Normal Activity, Exercise, and Seizures in Subjects With Epilepsy Completed NCT01214707 Phase 4
34 An Observational Study to Evaluate Long-term Retention Rate of Topiramate in Participants With Epilepsy Completed NCT01682681 Phase 4 Topiramate
35 Open-label, Multi-center Trial of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy Completed NCT01140867 Phase 4 zonisamide
36 Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal Epilepsy Completed NCT01190098 Phase 4 Lacosamide;Placebo
37 Spanish Validation Of Quality of Life Questionnaire (QOLIE-10) For Epilepsy Completed NCT00264680 Phase 4 lamotrigine;valproic acid
38 A Study to Assess Tolerability and Efficacy of Topiramate Monotherapy in Recently Diagnosed Patients With Epilepsy Completed NCT01689649 Phase 4 Topiramate
39 Women With Epilepsy: a Pilot Study of PK and PD Anti-epileptic Drug Effects in Levonorgestrel Intrauterine System Users Completed NCT02362373 Phase 4 levonorgestrel IUS
40 Quality of Life and Adverse Effects in Epilepsy Patients (EPIKA) Completed NCT00302991 Phase 4
41 Open Label Study of Zonisamide in the Treatment of Epilepsy in Patients With Mental Retardation Completed NCT00298818 Phase 4
42 Non-Interventional Study With LYRICA (Pregabalin) In Patients With Epilepsy As Adjunctive Therapy Of Partial Seizures To Reduce Seizure Frequency Completed NCT00684424 Phase 4
43 S.K.A.T.E.: Safety of Keppra as Adjunctive Therapy in Epilepsy Completed NCT00630968 Phase 4 Levetiracetam (Keppra)
44 Study of Valproate in Young Patients Suffering From Epilepsy Completed NCT00385411 Phase 4 valproate microgranules
45 Effect of Three Different Doses of Oral Cholecalciferol on 25-Hydroxyvitamin D Changes Among Epilepsy Patients With Hypovitaminosis D Completed NCT02890823 Phase 4 Cholecalciferol
46 Levetiracetam Versus Oxcarbazepine as Monotherapy to Evaluate Efficacy and Safety in Subjects With Newly or Recently Diagnosed Partial Epilepsy Completed NCT01498822 Phase 4 Levetiracetam;Oxcarbazepine
47 Open Label Safety and Efficacy Study of Levetiracetam in Patients With Epilepsy Completed NCT00160654 Phase 4 Levetiracetam
48 A Cross-sectional Study to Investigate the Effect of Topiramate on Bone and Mineral Metabolism in Female Participants With Epilepsy Completed NCT01030094 Phase 4 Topiramate;Carbamazepine;Valproic acid;Normal control
49 Methylphenidate for Treating Attention Deficit Hyperactivity Disorder in Children With Both ADHD and Epilepsy Completed NCT00323947 Phase 4 Extended Release Methylphenidate (OROS-Methylphenidate)
50 A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of Epilepsy Completed NCT00266604 Phase 4 Topiramate

Search NIH Clinical Center for Epilepsy

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: epilepsy

Genetic Tests for Epilepsy

Genetic tests related to Epilepsy:

id Genetic test Affiliating Genes
1 Epilepsy 24

Anatomical Context for Epilepsy

MalaCards organs/tissues related to Epilepsy:

39
Temporal Lobe, Brain, Testes, Cortex, Bone, Heart, Thalamus

Publications for Epilepsy

Articles related to Epilepsy:

(show top 50) (show all 6643)
id Title Authors Year
1
Epilepsy in fragile-X-syndrome mimicking panayiotopoulos syndrome: Description of three patients. ( 28815953 )
2017
2
Hamartia in hippocampal sclerosis-associated mesial temporal lobe epilepsy. ( 28888331 )
2017
3
Myoclonus epilepsy and ataxia due to KCNC1 mutation: Analysis of 20 cases and K(+) channel properties. ( 28380698 )
2017
4
Whole-transcriptome sequencing in blood provides a diagnosis of spinal muscular atrophy with progressive myoclonic epilepsy. ( 28251733 )
2017
5
Disease-modifying effect of atipamezole in a model of post-traumatic epilepsy. ( 28753497 )
2017
6
Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients. ( 28884208 )
2017
7
Navigation-assisted trans-inferotemporal cortex selective amygdalohippocampectomy for mesial temporal lobe epilepsy; preserving the temporal stem. ( 28067149 )
2017
8
Historical perspective on the medical use of cannabis for epilepsy: Ancient times to the 1980s. ( 28089286 )
2017
9
Patterns of Gray Matter Abnormalities in Idiopathic Generalized Epilepsy: A Meta-Analysis of Voxel-Based Morphology Studies. ( 28060866 )
2017
10
Epilepsy surgery for epileptic encephalopathy as a sequela of herpes simplex encephalitis: case report. ( 28452654 )
2017
11
Association of a synonymous SCN1B variant affecting splicing efficiency with Benign Familial Infantile Epilepsy (BFIE). ( 28566192 )
2017
12
Hemimegalencephaly with intractable epilepsy: A case report. ( 28924292 )
2017
13
Prognostic factors in patients with refractory idiopathic generalized epilepsy. ( 28157601 )
2017
14
Corrigendum to 'Cost-Utility of Video-Electroencephalography Monitoring Followed by Surgery in Adults with Drug-Resistant Focal Epilepsy in Thailand' [World Neurosurgery 98 (2017) 750-760]. ( 28633983 )
2017
15
Asystole in focal epilepsy complicating a traumatic subdural hematoma. ( 28765766 )
2017
16
Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology. ( 27966542 )
2017
17
Risk of post-traumatic epilepsy after severe head injury in patients with at least one seizure. ( 28919762 )
2017
18
The preclinical discovery and development of brivaracetam for the treatment of focal epilepsy. ( 28829199 )
2017
19
Pharmacists' knowledge of issues in pharmacotherapy of epilepsy using antiepileptic drugs: A cross-sectional study in Palestinian pharmacy practice. ( 28088050 )
2017
20
Multi-modal imaging and photosensitive epilepsy: a link between resting brain rhythms and seizure genesis. ( 28375460 )
2017
21
A career in epilepsy. ( 28089367 )
2017
22
Cognition in patients with benign epilepsy with centrotemporal spikes: A study with long-term VEEG and RS-fMRI. ( 28882722 )
2017
23
Dengue fever triggering hemiconvulsion hemiplegia epilepsy in a child. ( 28488637 )
2017
24
TRIF contributes to epileptogenesis in temporal lobe epilepsy during TLR4 activation. ( 28867282 )
2017
25
Seizures Induced by Exiting Water: A Unique Form of Reflex Epilepsy. ( 28859025 )
2017
26
Association of CYP2C9, CYP2A6, ACSM2A, and CPT1A gene polymorphisms with adverse effects of valproic acid in Chinese patients with epilepsy. ( 28315807 )
2017
27
Bimodal coupling of ripples and slower oscillations during sleep in patients with focal epilepsy. ( 28948998 )
2017
28
Combined electroencephalography-functional magnetic resonance imaging and electrical source imaging improves localization of pediatric focal epilepsy. ( 28749544 )
2017
29
Frequency of CNKSR2 mutation in the X-linked epilepsy-aphasia spectrum. ( 28098945 )
2017
30
Nodding syndrome, other forms of epilepsy, and the Nakalanga syndrome most likely directly or indirectly caused by Onchocerca volvulus. ( 27745691 )
2017
31
New SMARCA2 mutation in a patient with Nicolaides-Baraitser syndrome and myoclonic astatic epilepsy. ( 27665729 )
2017
32
Pretreatment behavior and subsequent medication effects in childhood absence epilepsy. ( 28916534 )
2017
33
Arachnoid Cysts And Adult Onset Epilepsy. ( 28246242 )
2017
34
Hemiconvulsion-hemiplegia-epilepsy syndrome in a child with pre-existing cerebral pathology. ( 28652222 )
2017
35
Pretreatment seizure semiology in childhood absence epilepsy. ( 28724582 )
2017
36
Altered functional connectivity in mesial temporal lobe epilepsy. ( 28923408 )
2017
37
Phosphoglycerate dehydrogenase (PHGDH) deficiency without epilepsy mimicking primary microcephaly. ( 28440900 )
2017
38
Diagnostic targeted resequencing in 349 patients with drug-resistant pediatric epilepsies identifies causative mutations in 30 different genes. ( 27864847 )
2017
39
Psychogenic nonepileptic seizures in patients with surgically treated temporal lobe epilepsy: Presurgical and de novo postsurgical occurrence. ( 28867568 )
2017
40
A critical assessment of the association between postnatal toxoplasmosis and epilepsy in immune-competent patients. ( 28083719 )
2017
41
Identification of two mutations in cis in the SCN1A gene in a family showing genetic epilepsy with febrile seizures plus (GEFS+) and idiopathic generalized epilepsy (IGE). ( 28951233 )
2017
42
Reduced steroidogenesis in patients with PCDH19-female limited epilepsy. ( 28471529 )
2017
43
Features of stimulus-specific seizures in dogs with reflex epilepsy: 43 cases (2000-2014). ( 28001116 )
2017
44
"Atypical forms" of benign epilepsy with centrotemporal spikes (BECTS): How to diagnose and guide these children. A practical/scientific approach. ( 28866336 )
2017
45
Low glycemic index treatment for seizure control in Angelman syndrome: A case series from the Center for Dietary Therapy of Epilepsy at the Massachusetts General Hospital. ( 28109989 )
2017
46
Rabies Tracing of Birthdated Dentate Granule Cells in Rat Temporal Lobe Epilepsy. ( 28470680 )
2017
47
Epilepsy and sleep disorders improve in adolescents and adults with Angelman syndrome: A multicenter study on 46 patients. ( 28827041 )
2017
48
Clinical stabilisation with lacosamide of mood disorder comorbid with PTSD and fronto-temporal epilepsy. ( 28845834 )
2017
49
Obstructive Hydrocephalus in Pyridoxine-Dependent Epilepsy: An Uncommon Complication. ( 28216032 )
2017
50
Deep brain stimulation for refractory temporal lobe epilepsy: a systematic review and meta-analysis with an emphasis on alleviation of seizure frequency outcome. ( 28921161 )
2017

Variations for Epilepsy

Copy number variations for Epilepsy from CNVD:

7 (show top 50) (show all 613)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 13367 1 1 16700000 Deletion Epilepsy
2 17286 1 142400000 148000000 Deletion Epilepsy
3 17377 1 142600000 147000000 Deletion Epilepsy
4 18328 1 145000000 145900000 Deletion GJA8 Epilepsy
5 33187 1 43391045 43424847 Deletion SLC2A1 Epilepsy
6 36112 1 72040000 72150000 Deletion NEGR1 Epilepsy
7 41452 10 18271821 21110683 Deletion Epilepsy
8 43051 10 43288081 55324785 Duplication Epilepsy
9 43386 10 46384979 512