MCID: EPT008
MIFTS: 34

Epithelioid Malignant Peripheral Nerve Sheath Tumor malady

Neuronal diseases, Cancer diseases categories
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Summaries for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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MalaCards: Epithelioid Malignant Peripheral Nerve Sheath Tumor, also known as malignant epithelioid neoplasm of the peripheral nerve sheath, is related to malignant peripheral nerve sheath tumor and neuroblastoma. An important gene associated with Epithelioid Malignant Peripheral Nerve Sheath Tumor is S100B (S100 calcium binding protein B), and among its related pathways is PEDF Induced Signaling. The compounds s 100 and l-amino acid have been mentioned in the context of this disorder. Affiliated tissues include thyroid, and related mouse phenotype hematopoietic system.

Aliases & Classifications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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8Disease Ontology, 62UMLS, 40NCIt, 58SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

epithelioid malignant peripheral nerve sheath tumor 8 62
malignant epithelioid neoplasm of the peripheral nerve sheath 8
epithelioid mpnst 8


External Ids:

Disease Ontology8 DOID:8353
SNOMED-CT58 19897006
NCIt40 C6561

Related Diseases for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:



Diseases related to epithelioid malignant peripheral nerve sheath tumor

Symptoms for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Drugs & Therapeutics for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Anatomical Context for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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33MalaCards
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MalaCards organs/tissues related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

33
Thyroid

Animal Models for Epithelioid Malignant Peripheral Nerve Sheath Tumor or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.1CSF3, PRG2, NGFR, SMARCB1

Publications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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52PubMed
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Articles related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

(show all 14)
idTitleAuthorsYear
1
Rapidly progressive epithelioid malignant peripheral nerve sheath tumor of the vestibular nerve. (23988994)
2013
2
Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. (22082606)
2012
3
Advanced epithelioid malignant peripheral nerve sheath tumor showing complete response to combined surgery and chemotherapy: a case report. (22606446)
2011
4
Epithelioid malignant peripheral nerve sheath tumor of the uterine corpus. (20952276)
2011
5
Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. (17972308)
2008
6
Epithelioid malignant peripheral nerve sheath tumor in the infraorbital nerve. (16550070)
2006
7
Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration. (15991844)
2005
8
Epithelioid malignant peripheral nerve sheath tumor involving maxillary sinus. (16382783)
2005
9
Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. (15592781)
2004
10
Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. (11145248)
2001
11
Intraosseous epithelioid malignant peripheral nerve sheath tumor of the phalanx. Case report. (10230694)
1999
12
Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma). (9285192)
1997
13
Purely epithelioid malignant peripheral nerve sheath tumor of the vulva. (9142667)
1997
14
The purely epithelioid malignant peripheral nerve sheath tumor. (2425646)
1986

Variations for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Expression for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search GEO for disease gene expression data for Epithelioid Malignant Peripheral Nerve Sheath Tumor.

Pathways for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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50PathCards, 53QIAGEN, 30KEGG
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Compounds for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Sources:
45Novoseek, 11DrugBank, 61Tocris Bioscience, 51PharmGKB, 29IUPHAR, 24HMDB
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Compounds related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
1s 1004510.0CHGA, S100B
2l-amino acid459.9CHGA, S100B
3b 723459.9S100B, CHGA
4dbc-amp459.9S100B, NGFR
5dacarbazine45 1110.8CSF3, CHGA
6anti-fungal459.7CSF3, CHGA
7p003459.7CHGA, S100B
8c3bot (154-182)619.7PRG2, S100B
9ono 2506619.7PRG2, S100B
10nogo-66 (1-40)619.7PRG2, S100B
11mog (35-55)619.7PRG2, S100B
12plp (139-151)619.7PRG2, S100B
13carboplatin45 51 1111.7CHGA, CSF3
14estracyt459.6PRG2, CHGA
15phorbol459.6CHGA, NGFR
16estramustine phosphate459.6CHGA, PRG2
17bromodeoxyuridine459.5S100B, CHGA
18estramustine45 1110.5CHGA, PRG2
19catecholamine459.5NGFR, CHGA, S100B
20gaba459.5S100B, CHGA, NGFR
21paraffin459.4NGFR, CHGA, S100B
22forskolin45 51 1111.4S100B, CHGA, NGFR
23etoposide45 51 61 1112.4S100B, CSF3, CHGA
24dopamine45 29 24 1112.4NGFR, CHGA, S100B
25paclitaxel45 51 1111.4S100B, CSF3, CHGA
26thymidine45 2410.4NGFR, CSF3, S100B
27cyclic amp45 2410.4S100B, CHGA, NGFR
28progesterone45 29 61 24 1113.3NGFR, CHGA, S100B
29steroid459.3S100B, CHGA, NGFR
30citrate459.2S100B, CHGA
31nadph45 2410.1S100B, PRG2, NGFR
32leucine459.1NGFR, PRG2, S100B
33histamine45 29 2411.0PRG2, CHGA, NGFR
34glutamate459.0S100B, CHGA, NGFR
35superoxide45 2410.0CSF3, PRG2, NGFR
36dexamethasone45 51 29 1112.0S100B, CSF3, CHGA, NGFR
37vegf459.0NGFR, CHGA, CSF3, S100B
38oligonucleotide458.9PRG2, CHGA, NGFR
39arginine458.8S100B, PRG2, CHGA
40hematoxylin458.7S100B, PRG2, CHGA, NGFR
41acetylcholine45 51 29 24 1112.7NGFR, CHGA, PRG2, S100B
42zinc45 249.7NGFR, CHGA, PRG2, S100B
43nitric oxide45 24 1110.7S100B, PRG2, CHGA, NGFR
44oxygen45 249.7NGFR, CHGA, PRG2, S100B
45estrogen458.7NGFR, CHGA, PRG2, S100B
46cysteine458.6NGFR, CHGA, PRG2, S100B
47lipid458.6S100B, PRG2, CHGA, NGFR
48calcium45 51 24 1111.3NGFR, CHGA, PRG2, S100B
49retinoic acid45 249.2NGFR, CHGA, PRG2, CSF3, S100B
50tyrosine458.2S100B, CSF3, PRG2, CHGA, NGFR

GO Terms for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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16Gene Ontology
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Cellular components related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.3S100B, PRG2, CHGA, NGFR

Biological processes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1central nervous system developmentGO:0074179.6S100B, NGFR

Products for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Sources for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet