MCID: EPT008
MIFTS: 25

Epithelioid Malignant Peripheral Nerve Sheath Tumor malady

Neuronal, Cancer categories

Summaries for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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33MalaCards
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MalaCards: Epithelioid Malignant Peripheral Nerve Sheath Tumor, also known as malignant epithelioid neoplasm of the peripheral nerve sheath, is related to papillary carcinoma and angiosarcoma. An important gene associated with Epithelioid Malignant Peripheral Nerve Sheath Tumor is S100B (S100 calcium binding protein B). The compounds s 100 and l-amino acid have been mentioned in the context of this disorder. Affiliated tissues include thyroid.

Aliases & Classifications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
8Disease Ontology, 61UMLS, 40NCIt, 57SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Neuronal


Aliases & Descriptions:

epithelioid malignant peripheral nerve sheath tumor 8 61
malignant epithelioid neoplasm of the peripheral nerve sheath 8
epithelioid mpnst 8


External Ids:

Disease Ontology8 DOID:8353
SNOMED-CT57 19897006
NCIt40 C6561

Related Diseases for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1papillary carcinoma10.4
2angiosarcoma10.4
3esophagitis10.0PRG2
4granular cell tumor10.0S100B
5rhinitis10.0PRG2
6chondrosarcoma10.0S100B
7ganglioneuroblastoma10.0S100B
8neuroblastoma10.0NGFR
9thymoma10.0NGFR
10stomach cancer10.0NGFR
11deficiency anemia10.0CSF3
12phaeochromocytoma10.0CHGA
13neuroendocrine tumor10.0CHGA
14malignant glioma10.0NGFR
15adenoma10.0CHGA
16pituitary adenoma10.0CHGA
17amyotrophic lateral sclerosis10.0NGFR
18epithelioid sarcoma10.0SMARCB1
19rhabdoid tumor10.0SMARCB1
20neurilemmoma10.0SMARCB1
21collecting duct carcinoma10.0SMARCB1
22schizophrenia10.0S100B
23chordoma10.0S100B
24wilms tumor10.0SMARCB1
25asthma10.0NGFR, PRG2
26ependymoma10.0NGFR, S100B
27malignant peripheral nerve sheath tumor10.0S100B, NGFR
28multiple sclerosis10.0NGFR, PRG2
29ganglioglioma10.0CHGA, S100B
30neurofibromatosis10.0NGFR, S100B
31pineocytoma10.0S100B, CHGA
32hemangiopericytoma10.0NGFR, S100B
33intraocular melanoma10.0S100B, NGFR
34neuroendocrine carcinoma10.0S100B, CHGA
35neurofibroma10.0S100B, NGFR
36factor vii deficiency10.0CHGA, CSF3
37pheochromocytoma10.0NGFR, CHGA
38sarcoma10.0S100B, SMARCB1
39leiomyosarcoma10.0SMARCB1, S100B
40meningioma10.0SMARCB1, S100B
41retinoblastoma10.0SMARCB1, NGFR
42merkel cell carcinoma10.0CHGA
43pancreatic cancer10.0NGFR, CHGA
44peripheral primitive neuroectodermal tumor10.0S100B, CHGA
45astrocytoma10.0NGFR, PRG2, S100B
46melanoma10.0NGFR, PRG2, S100B
47breast cancer10.0NGFR, PRG2, CSF3
48prolactinoma10.0CHGA, NGFR
49ganglioneuroma10.0S100B, CHGA, NGFR
50acute leukemia10.0SMARCB1, CSF3

Graphical network of the top 20 diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:



Diseases related to epithelioid malignant peripheral nerve sheath tumor

Clinical Features for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Drugs & Therapeutics for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Anatomical Context for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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33MalaCards
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MalaCards organs/tissues related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

33
Thyroid

Animal Models for Epithelioid Malignant Peripheral Nerve Sheath Tumor or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
51PubMed
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Articles related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

(show all 20)
idTitleAuthorsYear
1
Rapidly progressive epithelioid malignant peripheral nerve sheath tumor of the vestibular nerve. (23988994)
2013
2
Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. (22082606)
2012
3
Advanced epithelioid malignant peripheral nerve sheath tumor showing complete response to combined surgery and chemotherapy: a case report. (22606446)
2011
4
Epithelioid malignant peripheral nerve sheath tumor of the uterine corpus. (20952276)
2011
5
Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. (17972308)
2008
6
Intraosseous malignant peripheral nerve sheath tumor with focal epithelioid differentiation of the thoracic spine. (17272904)
2007
7
Epithelioid malignant peripheral nerve sheath tumor in the infraorbital nerve. (16550070)
2006
8
Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration. (15991844)
2005
9
Epithelioid malignant peripheral nerve sheath tumor involving maxillary sinus. (16382783)
2005
10
Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. (15592781)
2004
11
Expression of protein gene product 9.5 in epithelioid and conventional malignant peripheral nerve sheath tumors. (11570907)
2001
12
Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. (11145248)
2001
13
Epithelioid variant of malignant peripheral nerve sheath tumor (malignant schwannoma) of the urinary bladder. (10556478)
1999
14
Intraosseous epithelioid malignant peripheral nerve sheath tumor of the phalanx. Case report. (10230694)
1999
15
Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma). (9285192)
1997
16
Purely epithelioid malignant peripheral nerve sheath tumor of the vulva. (9142667)
1997
17
Epithelioid variant of malignant peripheral nerve sheath tumor]. (9388863)
1996
18
Epithelioid variant of malignant peripheral nerve sheath tumor (malignant epithelioid schwannoma). (1746681)
1991
19
Malignant epithelioid peripheral nerve sheath tumor arising in a benign schwannoma. (3686324)
1987
20
The purely epithelioid malignant peripheral nerve sheath tumor. (2425646)
1986

Genetic Variations for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Expression for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search GEO for disease gene expression data for Epithelioid Malignant Peripheral Nerve Sheath Tumor.

Pathways for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Compounds for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 24HMDB, 60Tocris Bioscience, 50PharmGKB
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Compounds related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

(show all 41)
idCompoundScoreTop Affiliating Genes
1s 100459.9S100B, CHGA
2l-amino acid459.9CHGA, S100B
3b 723459.8CHGA, S100B
4dacarbazine45 1110.8CHGA, CSF3
5dopamine45 29 11 2412.7NGFR, CHGA
6c3bot (154-182)609.7S100B, PRG2
7ono 2506609.7S100B, PRG2
8nogo-66 (1-40)609.7S100B, PRG2
9mog (35-55)609.7S100B, PRG2
10plp (139-151)609.6S100B, PRG2
11anti-fungal459.6CSF3, CHGA
12estracyt459.6CHGA, PRG2
13estramustine phosphate459.5CHGA, PRG2
14estramustine45 1110.5PRG2, CHGA
15catecholamine459.5S100B, CHGA, NGFR
16gaba459.4NGFR, CHGA, S100B
17etoposide45 50 60 1112.4S100B, CSF3, CHGA
18paraffin459.4S100B, CHGA, NGFR
19forskolin45 50 1111.3NGFR, CHGA, S100B
20carboplatin45 50 1111.3CSF3, CHGA
21paclitaxel45 50 1111.3S100B, CSF3, CHGA
22dbc-amp459.3S100B, NGFR
23thymidine45 2410.2S100B, CSF3, NGFR
24hematoxylin459.2CHGA, PRG2, S100B
25cyclic amp45 2410.1NGFR, CHGA, S100B
26progesterone45 60 29 11 2413.1NGFR, CHGA, S100B
27nadph45 2410.0NGFR, PRG2, S100B
28histamine45 29 2411.0NGFR, CHGA, PRG2
29dexamethasone45 50 29 1111.9S100B, CSF3, CHGA, NGFR
30vegf458.9NGFR, CHGA, CSF3, S100B
31leucine458.9NGFR, PRG2, S100B
32superoxide45 249.8NGFR, PRG2, CSF3
33acetylcholine45 50 29 11 2412.7NGFR, CHGA, PRG2, S100B
34zinc45 249.6NGFR, CHGA, PRG2, S100B
35nitric oxide45 11 2410.6S100B, PRG2, CHGA, NGFR
36oxygen45 249.6NGFR, CHGA, PRG2, S100B
37estrogen458.6S100B, PRG2, CHGA, NGFR
38cysteine458.6NGFR, CHGA, PRG2, S100B
39lipid458.5S100B, PRG2, CHGA, NGFR
40retinoic acid45 249.2S100B, CSF3, PRG2, CHGA, NGFR
41tyrosine458.1NGFR, CHGA, PRG2, CSF3, S100B

GO Terms for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources:
16Gene Ontology
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Cellular components related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.3NGFR, CHGA, PRG2, S100B

Products for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epithelioid Malignant Peripheral Nerve Sheath Tumor

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet