MCID: EPT008
MIFTS: 34

Epithelioid Malignant Peripheral Nerve Sheath Tumor malady

Neuronal diseases, Cancer diseases categories

Summaries for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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34MalaCards
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MalaCards: Epithelioid Malignant Peripheral Nerve Sheath Tumor, also known as malignant epithelioid neoplasm of the peripheral nerve sheath, is related to malignant peripheral nerve sheath tumor and neuroblastoma. An important gene associated with Epithelioid Malignant Peripheral Nerve Sheath Tumor is S100B (S100 calcium binding protein B), and among its related pathways is PEDF Induced Signaling. The compounds s 100 and l-amino acid have been mentioned in the context of this disorder. Affiliated tissues include thyroid, and related mouse phenotype hematopoietic system.

Aliases & Classifications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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9Disease Ontology, 63UMLS, 41NCIt, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

epithelioid malignant peripheral nerve sheath tumor 9 63
malignant epithelioid neoplasm of the peripheral nerve sheath 9
epithelioid mpnst 9


External Ids:

Disease Ontology9 DOID:8353
SNOMED-CT59 19897006
NCIt41 C6561

Related Diseases for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:



Diseases related to epithelioid malignant peripheral nerve sheath tumor

Symptoms for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Drugs & Therapeutics for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Anatomical Context for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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34MalaCards
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MalaCards organs/tissues related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

34
Thyroid

Animal Models for Epithelioid Malignant Peripheral Nerve Sheath Tumor or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.1CSF3, PRG2, NGFR, SMARCB1

Publications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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53PubMed
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Articles related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

(show all 14)
idTitleAuthorsYear
1
Rapidly progressive epithelioid malignant peripheral nerve sheath tumor of the vestibular nerve. (23988994)
2013
2
Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. (22082606)
2012
3
Advanced epithelioid malignant peripheral nerve sheath tumor showing complete response to combined surgery and chemotherapy: a case report. (22606446)
2011
4
Epithelioid malignant peripheral nerve sheath tumor of the uterine corpus. (20952276)
2011
5
Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. (17972308)
2008
6
Epithelioid malignant peripheral nerve sheath tumor in the infraorbital nerve. (16550070)
2006
7
Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration. (15991844)
2005
8
Epithelioid malignant peripheral nerve sheath tumor involving maxillary sinus. (16382783)
2005
9
Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. (15592781)
2004
10
Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. (11145248)
2001
11
Intraosseous epithelioid malignant peripheral nerve sheath tumor of the phalanx. Case report. (10230694)
1999
12
Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma). (9285192)
1997
13
Purely epithelioid malignant peripheral nerve sheath tumor of the vulva. (9142667)
1997
14
The purely epithelioid malignant peripheral nerve sheath tumor. (2425646)
1986

Variations for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Expression for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search GEO for disease gene expression data for Epithelioid Malignant Peripheral Nerve Sheath Tumor.

Pathways for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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51PathCards, 54QIAGEN, 31KEGG
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Compounds for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Sources:
46Novoseek, 12DrugBank, 62Tocris Bioscience, 52PharmGKB, 30IUPHAR, 25HMDB
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Compounds related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
1s 1004610.0CHGA, S100B
2l-amino acid469.9CHGA, S100B
3b 723469.9S100B, CHGA
4dbc-amp469.9S100B, NGFR
5dacarbazine46 1210.8CSF3, CHGA
6anti-fungal469.7CSF3, CHGA
7p003469.7CHGA, S100B
8c3bot (154-182)629.7PRG2, S100B
9ono 2506629.7PRG2, S100B
10nogo-66 (1-40)629.7PRG2, S100B
11mog (35-55)629.7PRG2, S100B
12plp (139-151)629.7PRG2, S100B
13carboplatin46 52 1211.7CHGA, CSF3
14estracyt469.6PRG2, CHGA
15phorbol469.6CHGA, NGFR
16estramustine phosphate469.6CHGA, PRG2
17bromodeoxyuridine469.5S100B, CHGA
18estramustine46 1210.5CHGA, PRG2
19catecholamine469.5NGFR, CHGA, S100B
20gaba469.5S100B, CHGA, NGFR
21paraffin469.4NGFR, CHGA, S100B
22forskolin46 52 1211.4S100B, CHGA, NGFR
23etoposide46 52 62 1212.4S100B, CSF3, CHGA
24dopamine46 30 25 1212.4NGFR, CHGA, S100B
25paclitaxel46 52 1211.4S100B, CSF3, CHGA
26thymidine46 2510.4NGFR, CSF3, S100B
27cyclic amp46 2510.4S100B, CHGA, NGFR
28progesterone46 30 62 25 1213.3NGFR, CHGA, S100B
29steroid469.3S100B, CHGA, NGFR
30citrate469.2S100B, CHGA
31nadph46 2510.1S100B, PRG2, NGFR
32leucine469.1NGFR, PRG2, S100B
33histamine46 30 2511.0PRG2, CHGA, NGFR
34glutamate469.0S100B, CHGA, NGFR
35superoxide46 2510.0CSF3, PRG2, NGFR
36dexamethasone46 52 30 1212.0S100B, CSF3, CHGA, NGFR
37vegf469.0NGFR, CHGA, CSF3, S100B
38oligonucleotide468.9PRG2, CHGA, NGFR
39arginine468.8S100B, PRG2, CHGA
40hematoxylin468.7S100B, PRG2, CHGA, NGFR
41acetylcholine46 52 30 25 1212.7NGFR, CHGA, PRG2, S100B
42zinc46 259.7NGFR, CHGA, PRG2, S100B
43nitric oxide46 25 1210.7S100B, PRG2, CHGA, NGFR
44oxygen46 259.7NGFR, CHGA, PRG2, S100B
45estrogen468.7NGFR, CHGA, PRG2, S100B
46cysteine468.6NGFR, CHGA, PRG2, S100B
47lipid468.6S100B, PRG2, CHGA, NGFR
48calcium46 52 25 1211.3NGFR, CHGA, PRG2, S100B
49retinoic acid46 259.2NGFR, CHGA, PRG2, CSF3, S100B
50tyrosine468.2S100B, CSF3, PRG2, CHGA, NGFR

GO Terms for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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17Gene Ontology
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Cellular components related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.3S100B, PRG2, CHGA, NGFR

Biological processes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1central nervous system developmentGO:0074179.6S100B, NGFR

Products for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Sources for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet