MCID: EPT008
MIFTS: 32

Epithelioid Malignant Peripheral Nerve Sheath Tumor malady

Neuronal diseases, Cancer diseases categories

Summaries for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Epithelioid Malignant Peripheral Nerve Sheath Tumor, also known as malignant epithelioid neoplasm of the peripheral nerve sheath, is related to malignant peripheral nerve sheath tumor and neuroblastoma. An important gene associated with Epithelioid Malignant Peripheral Nerve Sheath Tumor is S100B (S100 calcium binding protein B). The compounds s 100 and l-amino acid have been mentioned in the context of this disorder. Affiliated tissues include thyroid.

Aliases & Classifications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
8Disease Ontology, 60UMLS, 39NCIt, 56SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

epithelioid malignant peripheral nerve sheath tumor 8 60
malignant epithelioid neoplasm of the peripheral nerve sheath 8
epithelioid mpnst 8


External Ids:

Disease Ontology8 DOID:8353
SNOMED-CT56 19897006
NCIt39 C6561

Related Diseases for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1malignant peripheral nerve sheath tumor31.4S100B, NGFR
2neuroblastoma30.6NGFR
3peripheral nerve schwannoma10.6
4papillary carcinoma10.4
5angiosarcoma10.4
6papillary thyroid carcinoma10.4
7thyroiditis10.4
8esophagitis10.0PRG2
9granular cell tumor10.0S100B
10rhinitis10.0PRG2
11chondrosarcoma10.0S100B
12ganglioneuroblastoma10.0S100B
13thymoma10.0NGFR
14stomach cancer10.0NGFR
15deficiency anemia10.0CSF3
16phaeochromocytoma10.0CHGA
17neuroendocrine tumor10.0CHGA
18malignant glioma10.0NGFR
19adenoma10.0CHGA
20pituitary adenoma10.0CHGA
21amyotrophic lateral sclerosis10.0NGFR
22epithelioid sarcoma10.0SMARCB1
23rhabdoid tumor10.0SMARCB1
24neurilemmoma10.0SMARCB1
25collecting duct carcinoma10.0SMARCB1
26schizophrenia10.0S100B
27chordoma10.0S100B
28wilms tumor10.0SMARCB1
29asthma10.0NGFR, PRG2
30ependymoma10.0NGFR, S100B
31multiple sclerosis10.0NGFR, PRG2
32ganglioglioma10.0CHGA, S100B
33neurofibromatosis10.0NGFR, S100B
34pineocytoma10.0S100B, CHGA
35hemangiopericytoma10.0NGFR, S100B
36intraocular melanoma10.0S100B, NGFR
37neuroendocrine carcinoma10.0S100B, CHGA
38neurofibroma10.0S100B, NGFR
39factor vii deficiency10.0CHGA, CSF3
40pheochromocytoma10.0NGFR, CHGA
41sarcoma10.0S100B, SMARCB1
42leiomyosarcoma10.0SMARCB1, S100B
43meningioma10.0SMARCB1, S100B
44retinoblastoma10.0SMARCB1, NGFR
45merkel cell carcinoma10.0CHGA
46pancreatic cancer10.0NGFR, CHGA
47peripheral primitive neuroectodermal tumor10.0S100B, CHGA
48astrocytoma10.0NGFR, PRG2, S100B
49melanoma10.0NGFR, PRG2, S100B
50breast cancer10.0NGFR, PRG2, CSF3

Graphical network of the top 20 diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:



Diseases related to epithelioid malignant peripheral nerve sheath tumor

Clinical Features for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section

Drugs & Therapeutics for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Drug clinical trials:

Search ClinicalTrials for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search NIH Clinical Center for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search CenterWatch for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Genetic Tests for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section

Anatomical Context for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

32
Thyroid

Animal Models for Epithelioid Malignant Peripheral Nerve Sheath Tumor or affiliated genes

About this section

Publications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
50PubMed
See all sources

Articles related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

(show all 20)
idTitleAuthorsYear
1
Rapidly progressive epithelioid malignant peripheral nerve sheath tumor of the vestibular nerve. (23988994)
2013
2
Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. (22082606)
2012
3
Advanced epithelioid malignant peripheral nerve sheath tumor showing complete response to combined surgery and chemotherapy: a case report. (22606446)
2011
4
Epithelioid malignant peripheral nerve sheath tumor of the uterine corpus. (20952276)
2011
5
Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. (17972308)
2008
6
Intraosseous malignant peripheral nerve sheath tumor with focal epithelioid differentiation of the thoracic spine. (17272904)
2007
7
Epithelioid malignant peripheral nerve sheath tumor in the infraorbital nerve. (16550070)
2006
8
Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration. (15991844)
2005
9
Epithelioid malignant peripheral nerve sheath tumor involving maxillary sinus. (16382783)
2005
10
Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. (15592781)
2004
11
Expression of protein gene product 9.5 in epithelioid and conventional malignant peripheral nerve sheath tumors. (11570907)
2001
12
Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. (11145248)
2001
13
Epithelioid variant of malignant peripheral nerve sheath tumor (malignant schwannoma) of the urinary bladder. (10556478)
1999
14
Intraosseous epithelioid malignant peripheral nerve sheath tumor of the phalanx. Case report. (10230694)
1999
15
Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma). (9285192)
1997
16
Purely epithelioid malignant peripheral nerve sheath tumor of the vulva. (9142667)
1997
17
Epithelioid variant of malignant peripheral nerve sheath tumor]. (9388863)
1996
18
Epithelioid variant of malignant peripheral nerve sheath tumor (malignant epithelioid schwannoma). (1746681)
1991
19
Malignant epithelioid peripheral nerve sheath tumor arising in a benign schwannoma. (3686324)
1987
20
The purely epithelioid malignant peripheral nerve sheath tumor. (2425646)
1986

Genetic Variations for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section

Expression for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search GEO for disease gene expression data for Epithelioid Malignant Peripheral Nerve Sheath Tumor.

Pathways for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section

Compounds for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 24HMDB, 59Tocris Bioscience, 49PharmGKB
See all sources

Compounds related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

(show all 41)
idCompoundScoreTop Affiliating Genes
1s 100449.9S100B, CHGA
2l-amino acid449.9CHGA, S100B
3b 723449.8CHGA, S100B
4dacarbazine44 1110.8CHGA, CSF3
5dopamine44 28 11 2412.7NGFR, CHGA
6c3bot (154-182)599.7S100B, PRG2
7ono 2506599.7S100B, PRG2
8nogo-66 (1-40)599.7S100B, PRG2
9mog (35-55)599.7S100B, PRG2
10plp (139-151)599.6S100B, PRG2
11anti-fungal449.6CSF3, CHGA
12estracyt449.6CHGA, PRG2
13estramustine phosphate449.5CHGA, PRG2
14estramustine44 1110.5PRG2, CHGA
15catecholamine449.5S100B, CHGA, NGFR
16gaba449.4NGFR, CHGA, S100B
17etoposide44 49 59 1112.4S100B, CSF3, CHGA
18paraffin449.4S100B, CHGA, NGFR
19forskolin44 49 1111.3NGFR, CHGA, S100B
20carboplatin44 49 1111.3CSF3, CHGA
21paclitaxel44 49 1111.3S100B, CSF3, CHGA
22dbc-amp449.3S100B, NGFR
23thymidine44 2410.2S100B, CSF3, NGFR
24hematoxylin449.2CHGA, PRG2, S100B
25cyclic amp44 2410.1NGFR, CHGA, S100B
26progesterone44 59 28 11 2413.1NGFR, CHGA, S100B
27nadph44 2410.0NGFR, PRG2, S100B
28histamine44 28 2411.0NGFR, CHGA, PRG2
29dexamethasone44 49 28 1111.9S100B, CSF3, CHGA, NGFR
30vegf448.9NGFR, CHGA, CSF3, S100B
31leucine448.9NGFR, PRG2, S100B
32superoxide44 249.8NGFR, PRG2, CSF3
33acetylcholine44 49 28 11 2412.7NGFR, CHGA, PRG2, S100B
34zinc44 249.6NGFR, CHGA, PRG2, S100B
35nitric oxide44 11 2410.6S100B, PRG2, CHGA, NGFR
36oxygen44 249.6NGFR, CHGA, PRG2, S100B
37estrogen448.6S100B, PRG2, CHGA, NGFR
38cysteine448.6NGFR, CHGA, PRG2, S100B
39lipid448.5S100B, PRG2, CHGA, NGFR
40retinoic acid44 249.2S100B, CSF3, PRG2, CHGA, NGFR
41tyrosine448.1NGFR, CHGA, PRG2, CSF3, S100B

GO Terms for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.3NGFR, CHGA, PRG2, S100B

Products for genes affiliated with Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Epithelioid Malignant Peripheral Nerve Sheath Tumor

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet