MCID: EPS001
MIFTS: 29

Epstein-Barr Virus Hepatitis malady

Categories: Gastrointestinal diseases, Skin diseases

Aliases & Classifications for Epstein-Barr Virus Hepatitis

Aliases & Descriptions for Epstein-Barr Virus Hepatitis:

Name: Epstein-Barr Virus Hepatitis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0050204

Summaries for Epstein-Barr Virus Hepatitis

Disease Ontology : 12 A viral hepatitis that results_in inflammation, located in liver, has material basis in Human herpesvirus 4 and has symptom headache, has symptom fatigue, has symptom fever, has symptom abdominal pain, has symptom nausea, and has symptom jaundice.

MalaCards based summary : Epstein-Barr Virus Hepatitis is related to hepatitis and tubular adenocarcinoma, and has symptoms including headache, fatigue and fever. An important gene associated with Epstein-Barr Virus Hepatitis is AHSG (Alpha 2-HS Glycoprotein), and among its related pathways/superpathways is Response to elevated platelet cytosolic Ca2+. The drugs Tenofovir and rituximab have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and b cells.

Related Diseases for Epstein-Barr Virus Hepatitis

Graphical network of the top 20 diseases related to Epstein-Barr Virus Hepatitis:



Diseases related to Epstein-Barr Virus Hepatitis

Symptoms & Phenotypes for Epstein-Barr Virus Hepatitis

Symptoms:

12
  • headache
  • fatigue
  • fever
  • abdominal pain
  • nausea
  • jaundice

Drugs & Therapeutics for Epstein-Barr Virus Hepatitis

Drugs for Epstein-Barr Virus Hepatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tenofovir Approved, Investigational Phase 4 147127-20-6 464205
2
rituximab Approved Phase 4 174722-31-7 10201696
3 Nucleic Acid Synthesis Inhibitors Phase 4
4 Anti-HIV Agents Phase 4
5 Anti-Infective Agents Phase 4
6 Anti-Retroviral Agents Phase 4
7 Reverse Transcriptase Inhibitors Phase 4
8 Antiviral Agents Phase 4
9
Niacin Approved, Investigational, Nutraceutical Phase 2, Phase 3 59-67-6 938
10
Riboflavin Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 83-88-5 493570
11
Nicotinamide Approved, Nutraceutical Phase 2, Phase 3 98-92-0 936
12
Thiamine Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-43-8 1130
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
14 Nicotinic Acids Phase 2, Phase 3
15 Trace Elements Phase 2, Phase 3
16 Vitamin B Complex Phase 2, Phase 3
17 Vitamins Phase 2, Phase 3
18 Protective Agents Phase 2, Phase 3
19 Micronutrients Phase 2, Phase 3
20 Antioxidants Phase 2, Phase 3
21 silymarin Nutraceutical Phase 2, Phase 3
22 Folate Nutraceutical Phase 2, Phase 3
23 Vitamin B3 Nutraceutical Phase 2, Phase 3
24 Vitamin B2 Nutraceutical Phase 2, Phase 3
25 Vitamin B9 Nutraceutical Phase 2, Phase 3
26 Thiamin Nutraceutical Phase 2, Phase 3
27 Milk Thistle Nutraceutical Phase 2, Phase 3
28 Vaccines
29 Immunoglobulin G
30 Immunoglobulins
31 Antibodies
32 Autoantibodies
33 Yellow Dock Nutraceutical

Interventional clinical trials:


id Name Status NCT ID Phase
1 To Compare the Efficacy of a Prophylactic Use of Tenofovir by Duration for the Non-Hodgkin's Lymphoma Recruiting NCT02585947 Phase 4
2 Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis Terminated NCT00755950 Phase 2, Phase 3
3 Prospective Study of Possible Infectious Disease - Associated Antigen Drive in Previously Untreated Indolent Lymphoma Completed NCT00582270
4 Study of Transfusion-Transmitted Infections Recruiting NCT00023023
5 Transfusion-related EBV Infection Among Allogeneic Stem Cell Transplant Pediatric Recipients Recruiting NCT02505789
6 Apheresis of Patients With Immunodeficiency Recruiting NCT01212055
7 Cohort of HIV Associated Lymphomas Active, not recruiting NCT01164436
8 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875

Search NIH Clinical Center for Epstein-Barr Virus Hepatitis

Genetic Tests for Epstein-Barr Virus Hepatitis

Anatomical Context for Epstein-Barr Virus Hepatitis

MalaCards organs/tissues related to Epstein-Barr Virus Hepatitis:

39
Liver, Skin, B Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Epstein-Barr Virus Hepatitis:

18
Liver

Publications for Epstein-Barr Virus Hepatitis

Articles related to Epstein-Barr Virus Hepatitis:

(show all 16)
id Title Authors Year
1
Anti-tumour necrosis factor treatment of severe psoriasis complicated by Epstein-Barr Virus hepatitis and subsequently by chronic hepatitis. ( 26278774 )
2015
2
Clinical Characteristics of Primary Epstein Barr Virus Hepatitis with Elevation of Alkaline Phosphatase and I^-Glutamyltransferase in Children. ( 24339294 )
2014
3
Unusual presentation of Epstein-Barr virus hepatitis treated successfully with valganciclovir. ( 24115018 )
2014
4
A population-based study of 135 lymphomas after solid organ transplantation: The role of Epstein-Barr virus, hepatitis C and diffuse large B-cell lymphoma subtype in clinical presentation and survival. ( 24164103 )
2013
5
Characteristics of Epstein-Barr virus hepatitis among patients with jaundice or acute hepatitis. ( 22554291 )
2012
6
Epstein Barr virus hepatitis. ( 21238898 )
2011
7
Epstein-Barr virus hepatitis: diagnostic value of in situ hybridization, polymerase chain reaction, and immunohistochemistry on liver biopsy from immunocompetent patients. ( 17721196 )
2007
8
Epstein Barr virus hepatitis: case series and review. ( 16711324 )
2006
9
[Epstein-Barr virus hepatitis associated with icterus--a case report]. ( 17066593 )
2006
10
Ganciclovir and the treatment of Epstein-Barr virus hepatitis. ( 16984606 )
2006
11
Primary Epstein-Barr virus hepatitis complicated by ascites with epstein-barr virus reactivation during primary cytomegalovirus infection. ( 12827012 )
2003
12
Brief report: Pediatric Burkitt lymphoma with concurrent chronic Epstein-Barr virus hepatitis. ( 10398194 )
1999
13
Comparison between sporadic cytomegalovirus hepatitis and Epstein-Barr virus hepatitis in previously healthy adults. ( 9138274 )
1997
14
Epstein-Barr virus hepatitis after liver transplantation. ( 8017367 )
1994
15
The spectrum of Epstein-Barr virus hepatitis in children. ( 3024140 )
1986
16
Near-fatal coagulopathy associated with Epstein-Barr virus hepatitis. ( 3012886 )
1986

Variations for Epstein-Barr Virus Hepatitis

Expression for Epstein-Barr Virus Hepatitis

Search GEO for disease gene expression data for Epstein-Barr Virus Hepatitis.

Pathways for Epstein-Barr Virus Hepatitis

Pathways related to Epstein-Barr Virus Hepatitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.88 AHSG F2 TF

GO Terms for Epstein-Barr Virus Hepatitis

Cellular components related to Epstein-Barr Virus Hepatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 AHSG F2 TF
2 extracellular space GO:0005615 9.43 AHSG F2 TF
3 secretory granule lumen GO:0034774 9.16 AHSG TF
4 endoplasmic reticulum lumen GO:0005788 9.13 AHSG F2 TF
5 blood microparticle GO:0072562 8.8 AHSG F2 TF

Biological processes related to Epstein-Barr Virus Hepatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.26 AHSG TF
2 platelet degranulation GO:0002576 9.16 AHSG TF
3 acute-phase response GO:0006953 8.96 AHSG F2
4 cellular protein metabolic process GO:0044267 8.8 AHSG F2 TF

Sources for Epstein-Barr Virus Hepatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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